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Shared Governance

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https://www.readbyqxmd.com/read/27913312/crossborder-travel-and-multidrugresistant-tuberculosis-mdrtb-in-europe
#1
Alberto Matteelli, Rosella Centis, Giorgia Sulis, Marina Tadolini
The number of international migrants worldwide has continued to grow rapidly over the past fifteen years and the trend is expected to continue, making the health matters associated with migration a crucial public health challenges faced by governments and societies. Multidrug-resistant tuberculosis is a paradigm of transmissible diseases that do not respect borders and poses a multifaceted and complex challenge on migrant health. The guiding principles for the health response are the respect of equity and human rights as well as the accurate analysis of epidemiological trends and determinants of TB in migrants...
November 29, 2016: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/27909261/measuring-nutrition-governance-an-analysis-of-commitment-capability-and-collaboration-in-nepal
#2
Patrick Webb, Shibani Ghosh, Robin Shrestha, Grace Namirembe, Sabi Gurung, Diplav Sapkota, Winnie Fay Bell, Dale Davis, Eileen Kennedy, Shailes Neupane, Swetha Manohar, Kedar Baral
BACKGROUND: Global commitments to nutrition have supported calls for better evidence to support effective investments at national level. However, too little attention has so far been paid to the role of governance in achieving impacts. OBJECTIVE: This article explores the ways by which the commitment and capabilities of policy implementers affect collaborative efforts for achieving nutrition goals. METHODS: Over 1370 structured interviews were held with government and nongovernment officials over 3 years in 21 districts...
December 2016: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/27904818/the-government-s-role-in-regulating-coordinating-and-standardizing-the-response-to-alzheimer-s-disease-anticipated-international-cooperation-in-the-area-of-intractable-and-rare-diseases
#3
REVIEW
Qi Tang, Peipei Song, Lingzhong Xu
The World Health Organization (WHO) has emphasized that aging of the population is inextricably linked to many other global public health issues, such as universal health coverage, non-communicable diseases, and disability. However, Alzheimer's Disease International (ADI) estimates that 46.8 million elderly people worldwide were living with dementia in 2015. Alzheimer's disease (AD), the most common form of dementia, is one of the most common neurodegenerative diseases and is the main cause of cognitive impairment...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27903828/staff-nurse-decisional-involvement-in-the-united-states-and-turkey
#4
Esra Ugur, Cindy A Scherb, Janet P Specht, Sevim Sen, Lydia K Lazzara
: The purpose of this descriptive comparative study is to compare the levels of decisional involvement of staff nurses between one Midwestern health care system in the United States with a nongovernmental University hospital in Turkey. The Decisional Involvement Scale was used for data collection. U.S. (n = 163) and Turkey (n = 50) staff nurses were included in the study. Both samples preferred more decisional involvement than they currently experienced. However, Turkish nurses experienced and preferred lower levels of decisional involvement than the U...
November 30, 2016: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/27900659/territorial-rights-and-carbon-sinks
#5
Steve Vanderheiden
Scholars concerned with abuses of the "resource privilege" by the governments of developing states sometimes call for national sovereignty over the natural resources that lie within its borders. While such claims may resist a key driver of the "resource curse" when applied to mineral resources in the ground, and are often recognized as among a people's territorial rights, their implications differ in the context of climate change, where they are invoked on behalf of a right to extract and combust fossil fuels that is set in opposition to global climate change mitigation imperatives...
November 29, 2016: Science and Engineering Ethics
https://www.readbyqxmd.com/read/27899599/pubchem-bioassay-2017-update
#6
Yanli Wang, Stephen H Bryant, Tiejun Cheng, Jiyao Wang, Asta Gindulyte, Benjamin A Shoemaker, Paul A Thiessen, Siqian He, Jian Zhang
PubChem's BioAssay database (https://pubchem.ncbi.nlm.nih.gov) has served as a public repository for small-molecule and RNAi screening data since 2004 providing open access of its data content to the community. PubChem accepts data submission from worldwide researchers at academia, industry and government agencies. PubChem also collaborates with other chemical biology database stakeholders with data exchange. With over a decade's development effort, it becomes an important information resource supporting drug discovery and chemical biology research...
November 29, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27894307/regional-health-workforce-monitoring-as-governance-innovation-a-german-model-to-coordinate-sectoral-demand-skill-mix-and-mobility
#7
E Kuhlmann, O Lauxen, C Larsen
BACKGROUND: As health workforce policy is gaining momentum, data sources and monitoring systems have significantly improved in the European Union and internationally. Yet data remain poorly connected to policy-making and implementation and often do not adequately support integrated approaches. This brings the importance of governance and the need for innovation into play. CASE: The present case study introduces a regional health workforce monitor in the German Federal State of Rhineland-Palatinate and seeks to explore the capacity of monitoring to innovate health workforce governance...
November 28, 2016: Human Resources for Health
https://www.readbyqxmd.com/read/27889225/cost-estimate-and-proposal-for-a-development-impact-bond-for-canine-rabies-elimination-by-mass-vaccination-in-chad
#8
Franziska Anyiam, Monique Lechenne, Rolande Mindekem, Assandi Oussigéré, Service Naissengar, Idriss Oumar Alfaroukh, Celine Mbilo, Daugla Doumagoum Moto, Paul G Coleman, Nicole Probst-Hensch, Jakob Zinsstag
Close to 960,000 humans humans die of rabies each year, most of them in Africa and Asia. Clinical rabies can be prevented by post-exposure prophylaxis (PEP). However, PEP is commonly not available or not affordable in developing countries. Another strategy besides treating exposed humans is the vaccination of vector species. In developing countries, 8.36 vector is the domestic canine, that, once infected, is a serious threat to humans. After a successful mass vaccination of 70% of the dogs in N'Djaména, we report here a cost-estimate for a national rabies elimination campaign for Chad...
November 23, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27886527/universal-health-coverage-at-the-macro-level-synthetic-control-evidence-from-thailand
#9
Matthias Rieger, Natascha Wagner, Arjun S Bedi
As more and more countries are moving towards Universal Health Coverage (UHC), it is important to understand the macro level or aggregate impacts of such a policy. We use synthetic control methods to study the impact of UHC, introduced in Thailand in 2001, on various macroeconomic and health outcomes. Thailand is compared to a weighted average of control countries in terms of aggregate health financing indicators, aggregate health outcomes and economic performance, over the period 1995 to 2012. Our results suggest that UHC helps alleviate the financial consequences of illnesses...
November 17, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/27881091/conducting-a-large-multi-site-survey-about-patients-views-on-broad-consent-challenges-and-solutions
#10
Maureen E Smith, Saskia C Sanderson, Kyle B Brothers, Melanie F Myers, Jennifer McCormick, Sharon Aufox, Martha J Shrubsole, Nanibaá A Garrison, Nathaniel D Mercaldo, Jonathan S Schildcrout, Ellen Wright Clayton, Armand H Matheny Antommaria, Melissa Basford, Murray Brilliant, John J Connolly, Stephanie M Fullerton, Carol R Horowitz, Gail P Jarvik, Dave Kaufman, Terri Kitchner, Rongling Li, Evette J Ludman, Catherine McCarty, Valerie McManus, Sarah Stallings, Janet L Williams, Ingrid A Holm
BACKGROUND: As biobanks play an increasing role in the genomic research that will lead to precision medicine, input from diverse and large populations of patients in a variety of health care settings will be important in order to successfully carry out such studies. One important topic is participants' views towards consent and data sharing, especially since the 2011 Advanced Notice of Proposed Rulemaking (ANPRM), and subsequently the 2015 Notice of Proposed Rulemaking (NPRM) were issued by the Department of Health and Human Services (HHS) and Office of Science and Technology Policy (OSTP)...
November 24, 2016: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/27881085/the-ebola-outbreak-catalyzing-a-shift-in-global-health-governance
#11
Tim K Mackey
BACKGROUND: As the 2014 Ebola virus disease outbreak (EVD) transitions to its post-endemic phase, its impact on the future of global public health, particularly the World Health Organization (WHO), is the subject of continued debate. Criticism of WHO's performance grew louder in the outbreak's wake, placing this international health UN-specialized agency in the difficult position of navigating a complex series of reform recommendations put forth by different stakeholders. Decisions on WHO governance reform and the broader role of the United Nations could very well shape the future landscape of 21st century global health and how the international community responds to health emergencies...
November 24, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27879186/-to-reimburse-or-not-evaluating-expensive-drugs-differently
#12
J Stolk
Health insurance organisations grant reimbursement for drug treatment on the basis of results of placebo-controlled randomised clinical trials showing a clinically meaningful and statistically significant effect over placebo. This often proves problematic in rare diseases as well as in many chronic diseases that are difficult to treat. Clinical scientists may address the issue by testing the drug on surrogate outcome parameters and ask for post-marketing studies conducted by expert reference centres as expediency research, using budgets provided by the government to show that the drug really works in terms of real-life patient experience...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27878692/medical-employment-growth-unemployment-and-the-opportunity-cost-of-health-care
#13
Mark Pauly, Vivek Nimgaonkar
This policy note examines the relationship between the growth in the share of the workforce in medical care and the shares of workers who are unemployed, working in services or government employment, or working elsewhere in the economy. These changes provide measures of the opportunity cost of higher medical care spending, the majority of which is on labor. Using state data over the period 1990-2010, we find that, in years of high economy-wide unemployment, growth in medical employment in a state reduces the unemployment rate significantly; it does not appear to displace employment in other services or government employment...
December 2016: Int J Health Econ Manag
https://www.readbyqxmd.com/read/27876690/-mommy-blogs-and-the-vaccination-exemption-narrative-results-from-a-machine-learning-approach-for-story-aggregation-on-parenting-social-media-sites
#14
Timothy R Tangherlini, Vwani Roychowdhury, Beth Glenn, Catherine M Crespi, Roja Bandari, Akshay Wadia, Misagh Falahi, Ehsan Ebrahimzadeh, Roshan Bastani
BACKGROUND: Social media offer an unprecedented opportunity to explore how people talk about health care at a very large scale. Numerous studies have shown the importance of websites with user forums for people seeking information related to health. Parents turn to some of these sites, colloquially referred to as "mommy blogs," to share concerns about children's health care, including vaccination. Although substantial work has considered the role of social media, particularly Twitter, in discussions of vaccination and other health care-related issues, there has been little work on describing the underlying structure of these discussions and the role of persuasive storytelling, particularly on sites with no limits on post length...
November 22, 2016: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/27876457/providers-perspectives-on-inbound-medical-tourism-in-central-america-and-the-caribbean-factors-driving-and-inhibiting-sector-development-and-their-health-equity-implications
#15
Rory Johnston, Valorie A Crooks, Alejandro Cerón, Ronald Labonté, Jeremy Snyder, Emanuel O Núñez, Walter G Flores
BACKGROUND: Many governments and health care providers worldwide are enthusiastic to develop medical tourism as a service export. Despite the popularity of this policy uptake, there is relatively little known about the specific local factors prospectively motivating and informing development of this sector. OBJECTIVE: To identify common social, economic, and health system factors shaping the development of medical tourism in three Central American and Caribbean countries and their health equity implications...
2016: Global Health Action
https://www.readbyqxmd.com/read/27867504/short-rotation-plantations-policy-history-in-europe-lessons-from-the-past-and-recommendations-for-the-future
#16
REVIEW
Kevin N Lindegaard, Paul W R Adams, Martin Holley, Annette Lamley, Annika Henriksson, Stig Larsson, Hans-Georg von Engelbrechten, Gonzalo Esteban Lopez, Marcin Pisarek
Short rotation plantations (SRPs) are fast-growing trees (such as willow (Salix spp.), poplar (Populus spp.) and Eucalyptus) grown closely together and harvested in periods of 2-20 years. There are around 50,000 hectares of SRPs in Europe, a relatively small area considering that there have been supportive policy measures in many countries for 30 years. This paper looks at the effect that the policy measures used in different EU countries have had, and how other external factors have impacted on the development of the industry...
August 2016: Food and energy security
https://www.readbyqxmd.com/read/27866945/a-global-call-from-five-countries-to-collaborate-in-antibiotic-stewardship-united-we-succeed-divided-we-might-fail
#17
REVIEW
Debra A Goff, Ravina Kullar, Ellie J C Goldstein, Mark Gilchrist, Dilip Nathwani, Allen C Cheng, Kelly A Cairns, Kevin Escandón-Vargas, Maria Virginia Villegas, Adrian Brink, Dena van den Bergh, Marc Mendelson
In February, 2016, WHO released a report for the development of national action plans to address the threat of antibiotic resistance, the catastrophic consequences of inaction, and the need for antibiotic stewardship. Antibiotic stewardship combined with infection prevention comprises a collaborative, multidisciplinary approach to optimise use of antibiotics. Efforts to mitigate overuse will be unsustainable without learning and coordinating activities globally. In this Personal View, we provide examples of international collaborations to address optimal prescribing, focusing on five countries that have developed different approaches to antibiotic stewardship-the USA, South Africa, Colombia, Australia, and the UK...
November 17, 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27856299/als-and-ftd-linked-ggggcc-repeat-containing-dna-oligonucleotide-folds-into-two-distinct-g-quadruplexes
#18
Jasna Brčić, Janez Plavec
BACKGROUND: The most common genetic cause of neurological disorders ALS and FTD is a largely increased number of GGGGCC repeats in C9orf72 gene. Non-canonical structures including G-quadruplexes adopted by expanded repeats are hypothesized to be crucial in pathogenesis. Recently, we have shown that structural polymorphism of oligonucleotide d(G4C2)3G4 is reduced by dG to 8Br-dG substitution. High-resolution structure of one of the two major G-quadruplexes adopts antiparallel topology comprising of four G-quartets...
November 14, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27855099/cluster-randomised-feasibility-trial-to-improve-the-control-of-hypertension-in-rural-india-chiri-a-study-protocol
#19
Michaela A Riddell, Rohina Joshi, Brian Oldenburg, Clara Chow, K R Thankappan, Ajay Mahal, Nihal Thomas, Velandai K Srikanth, Roger G Evans, Kartik Kalyanram, Kamakshi Kartik, Pallab K Maulik, Simin Arabshahi, R P Varma, Rama K Guggilla, Oduru Suresh, G K Mini, Fabrizio D'Esposito, Thirunavukkarasu Sathish, Mohammed Alim, Amanda G Thrift
INTRODUCTION: Hypertension is emerging in rural populations of India. Barriers to diagnosis and treatment of hypertension may differ regionally according to economic development. Our main objectives are to estimate the prevalence, awareness, treatment and control of hypertension in 3 diverse regions of rural India; identify barriers to diagnosis and treatment in each setting and evaluate the feasibility of a community-based intervention to improve control of hypertension. METHODS AND ANALYSIS: This study includes 4 main activities: (1) assessment of risk factors, quality of life, socioeconomic position and barriers to changes in lifestyle behaviours in ∼14 500 participants; (2) focus group discussions with individuals with hypertension and indepth interviews with healthcare providers, to identify barriers to control of hypertension; (3) use of a medicines-availability survey to determine the availability, affordability and accessibility of medicines and (4) trial of an intervention provided by Accredited Social Health Activists (ASHAs), comprising group-based education and support for individuals with hypertension to self-manage blood pressure...
October 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/27851941/antimicrobial-peptides-share-a-common-interaction-driven-by-membrane-line-tension-reduction
#20
J Michael Henderson, Alan J Waring, Frances Separovic, Ka Yee C Lee
Antimicrobial peptides (AMPs) are a class of host-defense molecules that neutralize a broad range of pathogens. Their membrane-permeabilizing behavior has been commonly attributed to the formation of pores; however, with the continuing discovery of AMPs, many are uncharacterized and their exact mechanism remains unknown. Using atomic force microscopy, we previously characterized the disruption of model membranes by protegrin-1 (PG-1), a cationic AMP from pig leukocytes. When incubated with zwitterionic membranes of dimyristoylphosphocholine, PG-1 first induced edge instability at low concentrations, then porous defects at intermediate concentrations, and finally worm-like micelle structures at high concentrations...
November 15, 2016: Biophysical Journal
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