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https://www.readbyqxmd.com/read/29777908/breast-cancer-in-the-gcc-countries-a-focus-on-brca1-2-and-non-brca1-2-genes
#1
REVIEW
Sumaya Rahman, Hatem Zayed
The GCC is an economic alliance of six Arab countries, including Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates (UAE). The rate of endogamous marriage among the GCC countries is approaching 100%, with very high consanguineous marriage rates. Although breast cancer is on the rise in the GCC countries, there are dearth of studies reporting on the genetic epidemiology of breast cancer. In this study, we investigated the frequency of BRCA1/2 and non-BRCA1/2 mutations in breast cancer patients in the GCC countries...
May 16, 2018: Gene
https://www.readbyqxmd.com/read/29768370/a-case-report-of-neurological-complications-owing-to-lately-diagnosed-hyperargininemia-emphasizing-the-role-of-national-neonatal-screening-policies-in-the-kingdom-of-bahrain
#2
Moiz Bakhiet, Aminah M I AlAwadi, Maryam M AlHammadi, Maryam F Ali, Noora Butti
INTRODUCTION: Arginine is an essential amino acid that plays an important role in various body functions including cell division, wound healing, removal of ammonia, immune function, and release of hormones. Hyperargininemia, an autosomal recessive genetic disorder, is considered one of the least common urea cycle disorders. It rarely presents in the neonatal period but rather appears in children at the age between 2 and 4 years. CASE PRESENTATION: Herein, we demonstrate a case of a 14-year-old female who presented to the neurology clinic with several neurological complications, which were found to be a consequence of high levels of arginine discovered after performing a metabolic screening test...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29755807/assessing-the-prevalence-and-incidence-of-asthma-and-chronic-obstructive-pulmonary-disease-in-the-eastern-mediterranean-region
#3
Mohammadreza Masjedi, Elaheh Ainy, Faried Zayeri, Rogayeh Paydar
OBJECTIVES: This study conducted in 2016 aimed to assess the prevalence and incidence of asthma and chronic obstructive pulmonary disease (COPD) in the Eastern Mediterranean Region (EMR). MATERIAL AND METHODS: A meta-analysis to evaluate the published research relating to asthma and COPD was conducted using data from 23 EMR Office (EMRO) countries and searching using the web of science, PubMed, SciVerse Scopus, Google scholar, and MEDLINE databases. The keywords entered were all EMRO countries (Afghanistan, Bahrain, Djibouti, Egypt, Islamic republic Iran, Iraq, Jordan, Kuwait, Lebanon, Libyan Arab Jamahiriya, Morocco, Oman, Pakistan, Palestine, Qatar, Saudi Arab, Somalia, Sudan, Syrian Arab Republic, Tunisia, the United Arab Emirates, Yemen republic, and Cyprus) and asthma OR chronic obstructive pulmonary disease (COPD) OR (chronic bronchitis)...
April 2018: Turkish Thoracic Journal
https://www.readbyqxmd.com/read/29755305/a-cross-sectional-survey-study-to-assess-prevalence-and-attitudes-regarding-research-misconduct-among-investigators-in-the-middle-east
#4
Marwan Felaefel, Mohamed Salem, Rola Jaafar, Ghufran Jassim, Hillary Edwards, Fiza Rashid-Doubell, Reham Yousri, Nahed M Ali, Henry Silverman
Background: Recent studies from Western countries indicate significant levels of questionable research practices, but similar data from low and middle-income countries are limited. Our aims were to assess the prevalence of and attitudes regarding research misconduct among researchers in several universities in the Middle East and to identify factors that might account for our findings. Methods: We distributed an anonymous questionnaire to a convenience sample of investigators at several universities in Egypt, Lebanon, and Bahrain...
March 2018: Journal of Academic Ethics
https://www.readbyqxmd.com/read/29739473/undergraduate-medical-research-in-the-gulf-cooperation-council-gcc-countries-a-descriptive-study-of-the-students-perspective
#5
Zaid Sayedalamin, Taher Fawzy Halawa, Mukhtiar Baig, Osama Almutairi, Hassan Allam, Tahir Jameel, Zohair Jamil Gazzaz, Hazem Atta
OBJECTIVE: There is a lack of research-oriented physicians in several Arab countries and especially in Gulf region countries. In this context, it is important to explore medical students' perceptions and motivations towards research. The aim of the present study was to investigate research attitude, practices, and motivations among medical students from GCC countries. RESULTS: There were 228 students who participated in this study (male 88, females 140). Thirty-eight percent of the students were participating from Saudi Arabia, 20...
May 8, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29722635/recent-and-future-advances-in-anticancer-drug-delivery-an-interview-with-khaled-greish
#6
Khaled Greish
Khaled Greish speaks to Hannah Makin, Commissioning Editor: Khaled Greish is Associate Professor of Molecular Medicine, and head of the Nano-research unit, at Princes Al-Jawhara Center, Arabian Gulf University, Kingdom of Bahrain. His previous appointments included Senior lecturer of Pharmacology at the University of Otago, New Zealand, and Assistant Professor of Pharmaceutical Chemistry at University of Utah (UT, USA). He has published >70 peer reviewed papers, and ten book chapters in the field of targeted anticancer drug delivery...
May 1, 2018: Therapeutic Delivery
https://www.readbyqxmd.com/read/29718919/climate-change-impacts-on-marine-biodiversity-fisheries-and-society-in-the-arabian-gulf
#7
Colette C C Wabnitz, Vicky W Y Lam, Gabriel Reygondeau, Lydia C L Teh, Dalal Al-Abdulrazzak, Myriam Khalfallah, Daniel Pauly, Maria L Deng Palomares, Dirk Zeller, William W L Cheung
Climate change-reflected in significant environmental changes such as warming, sea level rise, shifts in salinity, oxygen and other ocean conditions-is expected to impact marine organisms and associated fisheries. This study provides an assessment of the potential impacts on, and the vulnerability of, marine biodiversity and fisheries catches in the Arabian Gulf under climate change. To this end, using three separate niche modelling approaches under a 'business-as-usual' climate change scenario, we projected the future habitat suitability of the Arabian Gulf (also known as the Persian Gulf) for 55 expert-identified priority species, including charismatic and non-fish species...
2018: PloS One
https://www.readbyqxmd.com/read/29666687/efficacy-of-ok-432-therapy-for-the-incisionless-treatment-of-head-and-neck-cystic-masses-case-series
#8
Hesham Y A Hasan, Muhammad A Rizwan
Head and neck masses can present in different pathologies that usually vary according to the age of the patient. We report five cases of benign head or neck masses occurring among patients of different ages who were managed at the Bahrain Defence Force Royal Medical Services Hospital, Ar-Rifaa, Bahrain, between 2005-2014. All of the patients were treated using the sclerotherapeutic agent OK-432. Although surgical removal is usually considered optimal treatment in the management of such cases, OK-432 appears to be a promising alternative...
February 2018: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29666684/item-analysis-of-multiple-choice-questions-at-the-department-of-paediatrics-arabian-gulf-university-manama-bahrain
#9
Deena Kheyami, Ahmed Jaradat, Tareq Al-Shibani, Fuad A Ali
Objectives: The current study aimed to carry out a post-validation item analysis of multiple choice questions (MCQs) in medical examinations in order to evaluate correlations between item difficulty, item discrimination and distraction effectiveness so as to determine whether questions should be included, modified or discarded. In addition, the optimal number of options per MCQ was analysed. Methods: This cross-sectional study was performed in the Department of Paediatrics, Arabian Gulf University, Manama, Bahrain...
February 2018: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29664716/identification-of-carbapenem-resistant-pseudomonas-aeruginosa-in-selected-hospitals-of-the-gulf-cooperation-council-states-dominance-of-high-risk-clones-in-the-region
#10
Hosam M Zowawi, Melanie W Syrmis, Timothy J Kidd, Hanan H Balkhy, Timothy R Walsh, Sameera M Al Johani, Reem Y Al Jindan, Mubarak Alfaresi, Emad Ibrahim, Amina Al-Jardani, Jameela Al Salman, Ali A Dashti, Hanna E Sidjabat, Omar Baz, Ella Trembizki, David M Whiley, David L Paterson
PURPOSE: The molecular epidemiology and resistance mechanisms of carbapenem-resistant Pseudomonas aeruginosa (CRPA) were determined in hospitals in the countries of the Gulf Cooperation Council (GCC), namely, Saudi Arabia, the United Arab Emirates, Oman, Qatar, Bahrain and Kuwait. METHODOLOGY: Isolates were screened for common carbapenem-resistance genes by PCR. Relatedness between isolates was assessed using previously described genotyping methods: an informative-single nucleotide polymorphism MassARRAY iPLEX assay (iPLEX20SNP) and the enterobacterial repetitive intergenic consensus (ERIC)-PCR assay, with selected isolates being subjected to multilocus sequence typing (MLST)...
April 17, 2018: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29658624/review-of-the-nutrition-situation-in-the-eastern-mediterranean-region
#11
REVIEW
Lara Nasreddine, Jennifer J Ayoub, Ayoub Al Jawaldeh
This situation analysis for the World Health Organization Eastern Mediterranean Region focuses on specific nutrition indicators, namely low birth weight, exclusive breastfeeding, under- and overnutrition (anthropometric indicators) and anaemia. The regional average prevalence of low birth weight and exclusive breastfeeding was estimated at 19.31% and 29.3%, respectively. Stunting, wasting and underweight had an average prevalence of 28%, 8.69% and 18%, respectively. Afghanistan, Djibouti, Pakistan, Sudan and Yemen had the highest burden of stunting (> 30%)...
April 5, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29658622/mpower-needs-and-challenges-trends-in-the-implementation-of-the-who-fctc-in-the-eastern-mediterranean-region
#12
REVIEW
Gholamreza Heydari, Ghazi Zaatari, Jawad A Al-Lawati, Fatimah El-Awa, Heba Fouad
Background: WHO MPOWER aims to help countries prioritize tobacco control measures in line with the WHO Framework Convention on Tobacco Control. Objectives: This paper assessed the progress and challenges in implementing the 6 priority policies of MPOWER in countries of the WHO Eastern Mediterranean Region since 2011. Methods: A checklist was developed and scores assigned based on the MPOWER indicators (maximum score 37). MPOWER data for the Region in the 2015 and 2017 tobacco control reports were extracted and scored...
April 5, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29541921/analyzing-the-psychometric-properties-of-the-short-form-36-quality-of-life-questionnaire-in-patients-with-obesity
#13
Rashed Al Amer, Khalid Al Khalifa, Safeyah Ali Alajlan, Ahmed Al Ansari
PURPOSE: The Short Form-36 (SF-36) questionnaire is a valuable and easy-to-use tool for the measurement of quality of life in patients with obesity. To become a widely used tool, the questionnaire must be validated in many different contexts. Thus, the present study aimed to evaluate the construct validity and reliability of the SF-36 questionnaire among patients with obesity in Bahrain. METHODOLOGY: The 36-item questionnaire was administered to a study cohort scheduled to undergo bariatric surgery at the Bahrain Defence Force Hospital in Bahrain...
March 14, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29541260/risk-stratification-and-in-hospital-morality-in-patients-presenting-with-acute-coronary-syndrome-acs-in-bahrain
#14
Taysir S Garadah, Khalid Bin Thani, Leena Sulibech, Ahmed A Jaradat, Mohamed E Al Alawi, Haytham Amin
Background: Risk factors and short-term mortality in patients presented with Acute Coronary Syndrome (ACS) in Bahrain has not been evaluated before. Aim: In this prospective observational study, we aim to determine the clinical risk profiles of patients with ACS in Bahrain and describe the incidence, pattern of presentation and predictors of in-hospital clinical outcomes after admission. Methods: Patients with ACS were prospectively enrolled over a 12 month period...
2018: Open Cardiovascular Medicine Journal
https://www.readbyqxmd.com/read/29528574/prevalence-of-vitamin-d-deficiency-in-adult-patients-with-systemic-lupus-erythematosus-in-kingdom-of-bahrain
#15
Eman Farid, Ahmed A Jaradat, Ola Al-Segai, Adla B Hassan
Vitamin D deficiency (VDD) has been implicated as an important factor in the development or aggravation of systemic lupus erythematous (SLE). Patients with SLE are especially prone to the development of VDD due to the nature of their illness and avoidance of sun exposure. The prevalence of VD status in Bahraini patients with SLE has not been studied. Our aim is to study the prevalence of VDD in Bahraini cohort with SLE. Fifty-eight Bahraini patients with SLE were included retrospectively in this study. Most of the patients were females 50/58...
June 2017: Egyptian Journal of Immunology
https://www.readbyqxmd.com/read/29528092/trend-and-seroprevalence-of-epstein-barr-virus-in-bahrain-2001-2015
#16
Eman Farid, Mohammed Al-Biltagi
In Bahrain, adequate epidemiological information is lacking concerning the rate of EBV infection, which could be helpful in order to develop measures to protect against EBV infections. The aim of this study, was to investigate the trend of EBV infection in Bahrain over a 15-year period, 2001-2015. The EBV serological results of 10 560 patients with possible EBV infection were evaluated. Samples taken at the Salmaniya Medical Complex during 2001-2015 were included. The presence or absence of EBV viral capsid antigen (VCA) IgG, VCA IgM and EBV nuclear antigen (EBNA) IgG antibodies was recorded...
March 5, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29508146/correction-to-emergency-medicine-in-the-kingdom-of-bahrain
#17
Feras Abuzeyad, Leena Alqasem, Mudhaffar I Al Farras, Shaikha S Al Jawder, Ghada Al Qasim, Salah Alghanem
Following the publication of the original article [1], it was brought to our attention that author Leena Alqasem was erroneously included as Leena Alqusem.
March 5, 2018: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29495011/potentially-inappropriate-prescribing-in-older-adults-with-hypertension-or-diabetes-mellitus-and-hypertension-at-primary-care-setting-in-bahrain
#18
Khalid Al Khaja, Husain Ahmed Isa, Sindhan Veeramuthu, Reginald P Sequeira
OBJECTIVES: The aims of the study were to evaluate: a) the prevalence and types of potentially inappropriate prescribing in older adults with hypertension or diabetes mellitus and hypertension; and b) whether or not the differences in training of primary care physicians was associated with the PIP. MATERIALS AND METHODS: Primary care prescriptions issued by family physicians and general practitioners were audited using Screening Tools of Older Person's Prescriptions criteria (version 1) with 18 out of 65 applicable criteria...
March 1, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29456449/international-comparison-of-five-herbal-medicine-registration-systems-to-inform-regulation-development-united-kingdom-germany-united-states-of-america-united-arab-emirates-and-kingdom-of-bahrain
#19
Azhar H Alostad, Douglas T Steinke, Ellen I Schafheutle
Background: Herbal medicine (HM) regulation is less developed than that of allopathic medicines, with some countries lacking specific regulations. Objective: For the purpose of informing a registration system for HMs in Kuwait, which does not manufacture but imports all HMs, this study compared the similarities and differences between the current HM registration systems of five countries. Methods: The five countries were selected as major source countries of HM in Kuwait (United Kingdom (UK), Germany and United States of America (USA)) or because of geographical proximity or size and approach (United Arab Emirates (UAE) and Kingdom of Bahrain)...
2018: Pharmaceutical Medicine
https://www.readbyqxmd.com/read/29445304/prevalence-of-medication-errors-in-primary-health-care-at-bahrain-defence-force-hospital-prescription-based-study
#20
Fatema Aljasmi, Fatema Almalood, Ahmed Al Ansari
Background: One of the important activities that physicians - particularly general practitioners - perform is prescribing. It occurs in most health care facilities and especially in primary health care (PHC) settings. Objectives: This study aims to determine what types of prescribing errors are made in PHC at Bahrain Defence Force (BDF) Hospital, and how common they are. Methods: This was a retrospective study of data from PHC at BDF Hospital...
2018: Drug, Healthcare and Patient Safety
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