keyword
MENU ▼
Read by QxMD icon Read
search

Zebra fish

keyword
https://www.readbyqxmd.com/read/28616013/corrigendum-zebra-fish-lacking-adaptive-immunity-acquire-an-antiviral-alert-state-characterized-by-upregulated-gene-expression-of-apoptosis-multigene-families-and-interferon-related-genes
#1
Pablo García-Valtanen, Alicia Martínez-López, Azucena López-Muñoz, Melissa Bello-Perez, Regla M Medina-Gali, María Del Mar Ortega-Villaizán, Monica Varela, Antonio Figueras, Víctoriano Mulero, Beatriz Novoa, Amparo Estepa, Julio Coll
[This corrects the article on p. 121 in vol. 8, PMID: 28243233.].
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28608678/new-insights-into-the-stability-of-silver-sulfide-nanoparticles-in-surface-water-dissolution-through-hypochlorite-oxidation
#2
Lingxiangyu Li, Zhenlan Xu, Andreas Wimmer, Qinghua Tian, Xin Ping Wang
Silver sulfide nanoparticles (Ag2SNPs) are considered to be stable in the environment due to the extreme low solubility of Ag2S (Ksp: 6.3×10-50). Little is known about the stability of Ag2SNPs in surface water disinfected with aqueous chlorine, one of the globally most used disinfectants. Our results suggested that both uncoated and polyvinylpyrrolidone (PVP)-coated Ag2SNPs (100 μg/L) underwent dissolution in surface water disinfected with aqueous chlorine at a dose of 4 mg/L, showing the highest dissolved silver ion concentrations of 22...
June 13, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28558981/natural-lipids-based-nlc-containing-lidocaine-from-pre-formulation-to-in-vivo-studies
#3
Lígia N M Ribeiro, Márcia C Breitkreitz, Viviane A Guilherme, Gustavo H R da Silva, Verônica M Couto, Simone R Castro, Bárbara O de Paula, Daisy Machado, Eneida de Paula
In a nanotechnological approach we have investigated the use of natural lipids in the preparation of nanostructured lipid carriers (NLC). Three different NLC composed of copaiba oil and beeswax, sweet almond oil and shea butter, and sesame oil and cocoa butter as structural matrices were optimized using factorial analysis; Pluronic® 68 and lidocaine (LDC) were used as the colloidal stabilizer and model encapsulated drug, respectively. The optimal formulations were characterized by different techniques (IR-ATR, DSC, and TEM), and their safety and efficacy were also tested...
May 27, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28528958/investigation-of-calcium-dependent-activity-and-conformational-dynamics-of-zebra-fish-12-lipoxygenase
#4
Monica Mittal, Mahmudul Hasan, Navisraj Balagunaseelan, Alexander Fauland, Craig Wheelock, Olof Rådmark, Jesper Z Haeggström, Agnes Rinaldo-Matthis
BACKGROUND: A 12-lipoxygenase in zebra fish (zf12-LOX) was found to be required for normal embryonic development and LOXs are of great interest for targeted drug designing. In this study, we investigate the structural-functional aspects of zf12-LOX in response to calcium. METHODS: A soluble version of zf12-LOX was created by mutagenesis. Based on multiple sequence alignment, we mutated the putative calcium-responsive amino acids in N-PLAT domain of soluble zf12-LOX...
August 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28515779/higher-resource-level-promotes-virulence-in-an-environmentally-transmitted-bacterial-fish-pathogen
#5
Hanna Kinnula, Johanna Mappes, Janne K Valkonen, Katja Pulkkinen, Lotta-Riina Sundberg
Diseases have become a primary constraint to sustainable aquaculture, but remarkably little attention has been paid to a broad class of pathogens: the opportunists. Opportunists often persist in the environment outside the host, and their pathogenic features are influenced by changes in the environment. To test how environmental nutrient levels influence virulence, we used strains of Flavobacterium columnare, an environmentally transmitted fish pathogen, to infect rainbow trout and zebra fish in two different nutrient concentrations...
June 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/28437728/is-a-a-o-process-effective-in-toxicity-removal-case-study-with-coking-wastewater
#6
Liu Shi, Dong Wang, Di Cao, Chunhong Na, Xie Quan, Ying Zhang
The anaerobic-anoxic-oxic (A/A/O) process is the commonly used biological wastewater treatment process, especially for the coking wastewater. However, limit is known about its ability in bio-toxicity removal from wastewater. In this study, we evaluated the performance of A/A/O process in bio-toxicity removal from the coking wastewater, using two test species (i.e. crustacean (Daphnia magna) and zebra fish (Danio rerio)) in respect of acute toxicity, oxidative damage and genotoxicity. Our results showed that the acute toxicity of raw influent was reduced gradually along with A/A/O process and the effluent presented no acute toxicity to Daphnia magna (D...
August 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28422363/the-occhiolino-occ-mutant-zebrafish-a-model-for-development-of-the-optical-function-in-the-biological-lens
#7
Masamoto Aose, Tor H Linbo, Owen Lawrence, Tadashi Senoo, David W Raible, John I Clark
BACKGROUND: Zebrafish visual function depends on quality optics. An F3 screen for developmental mutations in the Zebrafish nervous system was conducted in wild-type (wt) AB Zebrafish exposed to 3 mM of N-ethyl-N-nitrosourea (ENU). RESULTS: Mutant offspring, identified in an F3 screen, were characterized by a small pupil, resulting from retinal hypertrophy or hyperplasia and a small lens. Deficits in visual function made feeding difficult after hatching at approximately 5-6 days postfertilization (dpf)...
April 19, 2017: Developmental Dynamics: An Official Publication of the American Association of Anatomists
https://www.readbyqxmd.com/read/28369860/broad-shifts-in-the-resource-use-of-a-commercially-harvested-fish-following-the-invasion-of-dreissenid-mussels
#8
Shannon A Fera, Michael D Rennie, Erin S Dunlop
Dreissenid mussels, including the zebra (Dreissena polymorpha) and quagga (Dreissena rostiformus bugensis) mussel, are invasive species known for their capacity to act as ecosystem engineers. They have caused significant changes in the many freshwater systems they have invaded by increasing water clarity, reducing primary productivity, and altering zooplankton and benthic invertebrate assemblages. What is less clear is how their ecosystem engineering effects manifest up the food web to impact higher trophic levels, including fish...
June 2017: Ecology
https://www.readbyqxmd.com/read/28344476/effect-of-pelargonidin-isolated-from-ficus-benghalensis-l-on-phenotypic-changes-in-zebrafish-danio-rerio-embryos
#9
Uday Kundap, Yogini Jaiswal, Rachana Sarawade, Leonard Williams, Mohd Farooq Shaikh
In the present study, the extraction and isolation of Pelargonidin, an anthocyanin compound from stem bark of Ficus benghalensis are described. The study also involves evaluation of the effect of Pelargonidin on phenotypic variations in zebra fish embryos. Extraction and isolation of Pelargonidin were carried out by employing liquid-liquid extraction technique, phytochemical tests, column chromatography, UV and FT-IR. In the zebra fish embryo model, Paclitaxel was employed as a negative control. A series of phenotypic changes in different stages of embryonic development were studied with treatment concentrations of Pelargonidin between 3...
February 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28320082/rosmarinic-acid-plays-a-protective-role-in-the-embryogenesis-of-zebrafish-exposed-to-food-colours-through-its-influence-on-aurora-kinase-a-level
#10
Y Swarnalatha, I S Jerrine Joseph, Tippabathani Jayakrishna
OBJECTIVE: To evaluate the protective nature of the rosmarinic acid from Sphaeranthus amaranthoides during zebra fish embryogenesis. METHODS: Rosmarinic acid was isolated from the S. amaranthoides. An accurate, sensitive and simple LC-MS analysis was performed to determine the rosmarinic acid from S. amaranthoides. In the present study, zebrafish embryos were exposed to crimson red and sunset yellow at a concentration of 0.1 and 0.5mg/l and the effect of these food colours on the levels of aurora kinase A was studied individually...
May 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28288561/coinfection-outcome-in-an-opportunistic-pathogen-depends-on-the-inter-strain-interactions
#11
Hanna Kinnula, Johanna Mappes, Lotta-Riina Sundberg
BACKGROUND: In nature, organisms are commonly coinfected by two or more parasite strains, which has been shown to influence disease virulence. Yet, the effects of coinfections of environmental opportunistic pathogens on disease outcome are still poorly known, although as host-generalists they are highly likely to participate in coinfections. We asked whether coinfection with conspecific opportunistic strains leads to changes in virulence, and if these changes are associated with bacterial growth or interference competition...
March 14, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28254818/e-prostanoid-3-receptor-mediates-sprouting-angiogenesis-through-suppression-of-the-protein-kinase-a-%C3%AE-catenin-notch-pathway
#12
Di Chen, Juan Tang, Qiangyou Wan, Jian Zhang, Kai Wang, Yujun Shen, Ying Yu
OBJECTIVE: Angiogenesis is a hallmark of embryonic development and various ischemic and inflammatory diseases. Prostaglandin E2 receptor subtype 3 (EP3) plays an important role in pathophysiologic angiogenesis; however, the precise mechanisms remain unknown. Here, we investigated the role of EP3 in zebra fish embryo and mouse retina angiogenesis and evaluated the underlying mechanisms. APPROACH AND RESULTS: The EP3 receptor was highly expressed in the vasculature in both zebra fish embryos and murine fetal retinas...
May 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28249594/enhancement-of-scutellarin-oral-delivery-efficacy-by-vitamin-b12-modified-amphiphilic-chitosan-derivatives-to-treat-type-ii-diabetes-induced-retinopathy
#13
Jingnan Wang, Jiayun Tan, Jiahao Luo, Peilin Huang, Wuyi Zhou, Luming Chen, Lingli Long, Li-Ming Zhang, Banghao Zhu, Liqun Yang, David Y B Deng
BACKGROUND: Diabetic retinopathy is the most common complication in diabetic patients relates to high expression of VEGF and microaneurysms. Scutellarin (Scu) turned out to be effective against diabetes related vascular endothelial cell dysfunction. However, its clinical applications have been limited by its low bioavailability. In this study, we formulated and characterized a novel intestinal target nanoparticle carrier based on amphiphilic chitosan derivatives (Chit-DC-VB12) loaded with scutellarin to enhance its bioavailability and then evaluated its therapeutic effect in experimental diabetic retinopathy model...
March 1, 2017: Journal of Nanobiotechnology
https://www.readbyqxmd.com/read/28243233/zebra-fish-lacking-adaptive-immunity-acquire-an-antiviral-alert-state-characterized-by-upregulated-gene-expression-of-apoptosis-multigene-families-and-interferon-related-genes
#14
Pablo García-Valtanen, Alicia Martínez-López, Azucena López-Muñoz, Melissa Bello-Perez, Regla M Medina-Gali, María Del Mar Ortega-Villaizán, Monica Varela, Antonio Figueras, Víctoriano Mulero, Beatriz Novoa, Amparo Estepa, Julio Coll
To investigate fish innate immunity, we have conducted organ and cell immune-related transcriptomic as well as immunohistologic analysis in mutant zebra fish (Danio rerio) lacking adaptive immunity (rag1(-/-)) at different developmental stages (egg, larvae, and adult), before and after infection with spring viremia carp virus (SVCV). The results revealed that, compared to immunocompetent zebra fish (rag1(+/+) ), rag1(-/-) acquired increased resistance to SVCV with age, correlating with elevated transcript levels of immune genes in skin/fins and lymphoid organs (head kidney and spleen)...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28192999/intracellular-and-in-vivo-cyanide-mapping-via-surface-plasmon-spectroscopy-of-single-au-ag-nanoboxes
#15
Peiyuan Wang, Yujie Bai, Chi Yao, Xiaomin Li, Lei Zhou, Wenxing Wang, Ahmed Mohamed El-Toni, Jian Zi, Dongyuan Zhao, Lei Shi, Fan Zhang
Cyanide is extremely toxic to organisms but difficult to detect in living biological specimens. Here, we report a new CN(-) sensing platform based on unmodified Au-Ag alloy nanoboxes that etch in the presence of this analyte, yielding a shift in plasmon frequency that correlates with the analyte concentration. Significantly, when combined with dark field microscopy, these particle probes can be used to measure CN(-) concentrations in HeLa cells and in vivo in Zebra fish embryos. The limit of detection (LOD) of the novel method is 1 nM (below the acceptable limit defined by the World Health Organization), and finite-difference time-domain (FDTD) calculations are used to understand the CN(-) induced spectral shifts...
February 8, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28170238/dual-site-fluorescent-probe-for-visualizing-the-metabolism-of-cys-in-living-cells
#16
Yongkang Yue, Fangjun Huo, Peng Ning, Yongbin Zhang, Jianbin Chao, Xiangming Meng, Caixia Yin
Fluorescent probes, as noninvasive tools for visualizing the metabolism of biomolecules, hold great potential to explore their physiological and pathological processes. For cysteine (Cys), however, none of the reported fluorescent probes could image the metabolic processes in living cells. To achieve this goal, we developed a coumarin derivative based on rational design of the dual recognition sites for Cys and its metabolite, SO2. The probe displayed distinct two channels with turn-on fluorescent emission toward Cys and SO2, which were successfully applied for imaging both A549 cells and zebrafish...
February 15, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28156042/double-strand-dna-breaks-induced-by-paracyclophane-gold-i-complexes
#17
Sebastian Bestgen, Carmen Seidl, Thomas Wiesner, Andreas Zimmer, Martina Falk, Beate Köberle, Martina Austeri, Jan Paradies, Stefan Bräse, Ute Schepers, Peter W Roesky
Gold(I) complexes of ClickPhos [2.2]paracyclophane ligands were synthesized in excellent yields and fully characterized by spectroscopic methods as well as X-ray crystallography. The complexes exhibit a rigid ligand backbone and a triazolyl moiety and were systematically studied with respect to their cytotoxic properties. In combination with the ionic complex [(GemPhos)Au(tht)][ClO4 ] (tht=tetrahydrothiophene), in which the gold(I) atom exhibits a distorted trigonal coordination sphere of two phosphines and a labile tht ligand, their efficiency in cytotoxicity was investigated in HeLa, MCF7, and HCT116 cells as well as in a zebrafish model...
February 3, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28129381/comparative-cytogenetics-between-two-important-songbird-models-the-zebra-finch-and-the-canary
#18
Michelly da Silva Dos Santos, Rafael Kretschmer, Carolina Frankl-Vilches, Antje Bakker, Manfred Gahr, Patricia C M O Brien, Malcolm A Ferguson-Smith, Edivaldo H C de Oliveira
Songbird species (order Passeriformes, suborder Oscines) are important models in various experimental fields spanning behavioural genomics to neurobiology. Although the genomes of some songbird species were sequenced recently, the chromosomal organization of these species is mostly unknown. Here we focused on the two most studied songbird species in neuroscience, the zebra finch (Taeniopygia guttata) and the canary (Serinus canaria). In order to clarify these issues and also to integrate chromosome data with their assembled genomes, we used classical and molecular cytogenetics in both zebra finch and canary to define their chromosomal homology, localization of heterochromatic blocks and distribution of rDNA clusters...
2017: PloS One
https://www.readbyqxmd.com/read/28091617/switch-from-sexual-to-parthenogenetic-reproduction-in-a-zebra-shark
#19
Christine L Dudgeon, Laura Coulton, Ren Bone, Jennifer R Ovenden, Severine Thomas
Parthenogenesis is a natural form of asexual reproduction in which embryos develop in the absence of fertilisation. Most commonly found in plants and invertebrate organisms, an increasing number of vertebrate species have recently been reported employing this reproductive strategy. Here we use DNA genotyping to report the first demonstration of an intra-individual switch from sexual to parthenogenetic reproduction in a shark species, the zebra shark Stegostoma fasciatum. A co-housed, sexually produced daughter zebra shark also commenced parthenogenetic reproduction at the onset of maturity without any prior mating...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28075531/three-dimensional-imaging-flow-cytometry-through-light-sheet-fluorescence-microscopy
#20
REVIEW
Emilio J Gualda, Hugo Pereira, Gabriel G Martins, Rui Gardner, Nuno Moreno
Flow cytometry is the tool of choice for high-speed acquisition and analysis of large cell populations, with the tradeoff of lacking intracellular spatial information. Although in the last decades flow cytometry systems that can actually acquire two-dimensional spatial information were developed, some of the limitations remained though, namely constrains related to sample size and lack of depth or dynamic information. The combination of fluidics and light-sheet illumination has the potential to address these limitations...
February 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
keyword
keyword
80318
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"