keyword
https://read.qxmd.com/read/38443231/elderly-onset-rheumatoid-arthritis-receives-less-aggressive-therapies-than-young-onset-rheumatoid-arthritis-in-an-argentinian-cohort
#1
JOURNAL ARTICLE
Nicolás Pérez, María de Los Ángeles Gargiulo, Marina Khoury, Lorena Suárez, María de Los Ángeles Correa, Mariana Pera, Natali Saravia, Graciela Gómez
OBJECTIVES: When rheumatoid arthritis (RA) starts after the age of 60 it is called elderly-onset rheumatoid arthritis (EORA) and when it starts earlier, young-onset rheumatoid arthritis. (YORA). There are few Latin American studies that compared both groups. The objective of the study was to evaluate differences in the clinical characteristics, evolution and treatment among patients with RA with onset before or after 60 years of age. MATERIALS AND METHODS: Observational study of patients with RA attended consecutively in four centers in Argentina...
March 4, 2024: Reumatología clinica
https://read.qxmd.com/read/38443230/cardiovascular-event-in-a-cohort-of-rheumatoid-arthritis-patients-in-castilla-la-mancha-utility-of-carotid-ultrasound
#2
Marco Aurelio Ramírez Huaranga, David Velasco Sánchez, Luis Ángel Calvo Pascual, David Castro Corredor, María Dolores Mínguez Sánchez, Verónica Salas Manzanedo, Eva Revuelta Evrard, Rocío Arenal López, Joaquín Anino Fernández, Marina González Peñas, Lourdes Martin de la Sierra López, Laura María Jiménez Rodríguez, Alberto López Menchero Mora, Marcos Paulino Huertas
UNLABELLED: Rheumatoid Arthritis (RA) has a mortality rate 1,3 to 3 times higher than the general population, with cardiovascular mortality accounting for 40-50% of cases. Currently, cardiovascular disease is considered an extraarticular manifestation of RA (OR: 1,5-4,0). Ultrasound measurement of the intima-media thickness (IMT) of the common carotid artery and the presence of atherosclerotic plaques (AP) is a non-invasive method and a surrogate marker of subclinical arteriosclerosis...
March 4, 2024: Reumatología clinica
https://read.qxmd.com/read/38443229/ischiofemoral-impingement-syndrome-a-five-case-series-report
#3
Adrián Mayo-Juanatey, Luís García-Ferrer, Aránzazu Ballester-Suárez, Elia Valls-Pascual, Ignacio Vázquez-Gómez, Juan José Alegre-Sancho
Gluteal pain is a frequent cause of medical attention in the daily clinical practice. It can be caused by multiple pathologies, being ischiofemoral impingement syndrome among those included in its differential diagnosis. Encompassed within the deep gluteal syndromes, this entity occurs as a consequence of the entrapment of the neuromuscular structures between the lesser femoral trochanter and the ischial tuberosity, causing pain in the root of the lower limb, with irradiation towards the thigh or the gluteal region and poor tolerance to deambulation and sedestation...
March 4, 2024: Reumatología clinica
https://read.qxmd.com/read/38443228/pseudoseptic-arthritis-as-a-complication-of-intra-articular-infiltration-of-hyaluronic-acid-in-a-patient-with-rheumatoid-arthritis
#4
Chafik Chacur, Anastasia Mocritcaia, Raimon Sanmartí
Pseudoseptic arthritis is a rare complication of hyaluronic acid (HA) injections that often is difficult to differentiate from septic arthritis. Patients present acute pain, swelling and joint effusion normally around 24h after the second or third HA infiltration. We describe a female patient with seropositive rheumatoid arthritis and flare-ups of knee arthritis with pseudoseptic features in the past, who develops pseudoseptic arthritis of the knee following her first injection of hyaluronic acid.
March 4, 2024: Reumatología clinica
https://read.qxmd.com/read/38431489/usefulness-of-ultrasound-in-clinical-decision-making-in-rheumatology-clinical-practice-a-single-center-longitudinal-study
#5
Marta Serrano-Warleta, Aliuska Palomeque-Vargas, Rosa Manzo, Boris Blanco-Cáceres, Mónica Vazquez-Díaz, Carlos Guillen-Astete
OBJECTIVE: The purpose of the present study is to identify the extent to which it affects clinical decisions in a single-centre observational retrospective study. METHOD: The results of 801 requests and 1174 consecutive individual ultrasound examinations performed over 10 months were analysed. RESULTS: The most frequent indication was diagnostic assistance (39%) followed by assessment of inflammatory activity (34%). By topography, the hand was the most frequently studied region (51%), followed by the foot (18...
March 1, 2024: Reumatología clinica
https://read.qxmd.com/read/38395498/patient-journey-of-fibromyalgia-patients-a-scoping-review
#6
REVIEW
Teresa Otón, Loreto Carmona, Javier Rivera
BACKGROUND: Fibromyalgia (FM) is a chronic disease characterized by widespread pain. Although much is known about this disease, research has focused on diagnosis and treatment, leaving aside factors related to patient's experience and the relationship with healthcare system. OBJECTIVES: The aim was to analyze the available evidence on the experience of FM patients from the first symptoms to diagnosis, treatment, and follow-up. METHODS: A scoping review was carried out...
February 2024: Reumatología clinica
https://read.qxmd.com/read/38395497/clinical-features-of-patients-with-hands-arthralgia-referred-from-primary-care-physicians-to-rheumatologists-a-cohort-study
#7
JOURNAL ARTICLE
Gabriel Figueroa-Parra, Martha Mariana Castañeda-Martinez, Pablo Herrera-Sandate, Diana Daniela Castañeda-Martinez, Jorge Antonio Esquivel-Valerio, David Vega-Morales
PURPOSE: Early referral of patients with suspicious of rheumatoid arthritis (RA) has an impact on prognosis. Our study aimed to evaluate the clinical characteristics of patients with hands arthralgia who were referred from primary care physicians (PCP) to the rheumatologist. METHODS: A descriptive, observational, prospective cohort study was performed. We included patients who visited a PCP for the first time for hands arthralgia. Demographics and the European Alliance of Associations for Rheumatology criteria for arthralgia suspicious for progression to RA plus seven complementary questions, the time to referral, the pressure needed to provoke pain with an automatic squeeze test machine in the metacarpophalangeal joints of both hands, and the diagnoses established at the last review of medical charts from patients on follow-up were documented...
February 2024: Reumatología clinica
https://read.qxmd.com/read/38395496/quality-of-life-of-patients-with-rheumatic-diseases
#8
JOURNAL ARTICLE
Lourdes Villalobos-Sánchez, Boris Blanco-Cáceres, Javier Bachiller-Corral, María Teresa Rodríguez-Serrano, Mónica Vázquez-Díaz, Pablo Lázaro Y de Mercado
OBJECTIVE: Health-related quality of life (HRQoL) is an important indicator of population health and can measure the impact of medical actions. The main objective of this study was to determine the HRQoL of patients with rheumatic diseases (RD) and compare it with that of the general population. METHODS: Observational, cross-sectional, single-center study, with consecutive inclusion of outpatients over 18 years of age seen at a Rheumatology hospital-based outpatient clinic in Madrid...
February 2024: Reumatología clinica
https://read.qxmd.com/read/38395494/effect-of-combined-treatment-with-prednisone-and-methotrexate-versus-prednisone-alone-over-laboratory-parameters-in-giant-cell-arteritis
#9
RANDOMIZED CONTROLLED TRIAL
Ines Perez-Sancristobal, Paula Alvarez-Hernandez, Cristina Lajas-Petisco, Benjamin Fernandez-Gutierrez
OBJECTIVE: To compare the effect of combined treatment with prednisone and methotrexate (MTX) versus prednisone alone over laboratory parameters in giant cell arteritis (GCA). PATIENTS AND METHODS: We performed a double-blind, placebo-controlled, randomized clinical trial about usefulness of treatment with prednisone and MTX versus prednisone and placebo in GCA (Ann Intern Med 2001;134:106-114). As a part of follow-up of patients (n=42), we performed laboratory analysis in 20 time points during the two-year period of follow-up...
February 2024: Reumatología clinica
https://read.qxmd.com/read/38342740/health-personnel-perception-about-central-sensitivity-syndrome-fibromyalgia-patients
#10
JOURNAL ARTICLE
Gastón A Ghio, Angels Jaen Manzanera, Julia Torguet Carbonell, Camila Inés Donoso Isla, Alirio José Falcón Marchena, Silvia Martínez Pardo
BACKGROUND AND OBJECTIVES: Fibromyalgia is characterized by musculoskeletal pain and asthenia of chronic course. Fibromyalgia patients are often a challenge for the health care community as a whole. Existing studies are often limited to the opinion of rheumatologists or family physicians. With this study we seek to know what are the actions, perceptions and knowledge of health professionals as a whole when caring for patients with this disease. MATERIALS AND METHODS: Descriptive cross-sectional study, by means of a self-administered and anonymous survey...
February 10, 2024: Reumatología clinica
https://read.qxmd.com/read/38342739/the-activity-of-psoriatic-arthritis-with-axial-involvement-correlates-with-the-psaid12
#11
JOURNAL ARTICLE
Jose Antonio Pinto Tasende, Carlota Laura Iñiguez Ubiaga, Victor Eliseo Quevedo Vila, Luis Fernández Dominguez, Francisco Jose Maceiras Pan, Carlos García Porrúa
OBJECTIVE: To determine the impact of the disease in patients with PsA in daily clinical practice and to evaluate its relationship with its axial activity. METHODS: A cross-sectional study was conducted in consecutive patients attended from January 2021 to December 2021 who met the CASPAR criteria, with clinical of inflammatory back pain and positive axial imaging, with or without peripheral involvement. Demographic, clinical, analytical data, HAQ index, PsAID12 and activity index (BASDAI and ASDAS-PCR) were also collected...
February 10, 2024: Reumatología clinica
https://read.qxmd.com/read/38342738/comparison-of-plasma-inflammatory-biomarkers-between-mis-c-and-potentially-serious-infections-in-pediatric-patients
#12
JOURNAL ARTICLE
Núria Visa-Reñé, Adriana Rubio-Páez, Núria Mitjans-Rubies, Fernando Paredes-Carmona
BACKGROUND: Inflammatory biomarkers have been used for the diagnosis and management of multisystemic inflammatory syndrome in children (MIS-C). We aimed to compare the clinical and laboratory findings of MIS-C cases versus other febrile cases cataloged as potentially suspected bacterial infection (non-MIS-C). METHODS: Unicentric ambispective observational cohort study (June 2020-February 2022). We analyzed demographics, clinical symptoms and laboratory findings in MIS-C cases and in non-MIS-C cases with febrile processes of patients under 15 years of age admitted to hospital...
February 10, 2024: Reumatología clinica
https://read.qxmd.com/read/38290955/pleural-tuberculosis-and-endocarditis-as-complications-of-multifactorial-origin-in-granulomatosis-with-polyangiitis-clinical-case-report
#13
Jesús Anguamea-Maldonado, Eduardo Sanchez-Zazueta, Rene Vidal-Morales
We present the case of a 36-year-old woman with a history of granulomatosis with polyangiitis; chronic kidney disease; systemic arterial hypertension. Debut with dyspnea, weakness, and hemoptysis, she was suspected in atypical pneumonia, discarded, persisting with tachypnea, tachycardia, chest pain. The protocol for pulmonary tuberculosis was started with negative sputum samples, positive blood culture for S. haemolyticus, chest tomography with left pneumothorax and ipsilateral pleural effusion, exudate-type pleural fluid was obtained, acid-fast staining, negative PCR for M...
January 29, 2024: Reumatología clinica
https://read.qxmd.com/read/38290954/speciality-training-in-rheumatology-promotion-repetition-and-dropout-rates-in-the-city-of-buenos-aires
#14
Vanesa Laura Cosentino, Gustavo Casado, Carla Gobbi, Anastasia Secco, Félix Romanini, Gustavo Citera, Marcos Rosemffet, Silvia Papasidero, María Alejandra Medina, Juan Manuel Bande, Karen Roberts, Alejandro Brigante, Guillermo Pons Estel, María Celina de la Vega, Gabriel Sequeira, Eduardo Mario Kerzberg
OBJECTIVES: To evaluate the trajectory of students enrolled in the specialty training in rheumatology. METHODS: Retrospective analysis (2009-2016). Promotion, repetition, and dropout rates were determined. Analysis was performed to define variables associated with academic success. RESULTS: Out of 119 students, the actual promotion rate was 66.4%, 11.8% failed an exam (at least) and completed the course after the stipulated time, and the dropout rate was 7...
February 2024: Reumatología clinica
https://read.qxmd.com/read/38233011/osteoporosis-in-psoriatic-arthritis-risk-factors-insufficiency-fractures-and-its-association-with-the-disease-activity
#15
JOURNAL ARTICLE
María Paz Martínez-Vidal, Vega Jovani, José Raúl Noguera-Pons, Antonio Álvarez-Cienfuegos
OBJECTIVE: The prevalence of osteoporosis (OP) and insufficiency fractures in psoriatic arthritis (PsA) remains controversial. The aim of this study was to describe the prevalence of OP and insufficiency fractures in a representative cohort of patients with PsA, and to analyse its association with general risk factors and characteristics of the psoriatic disease in our geographical area. METHODS: Multi-centric, descriptive study of patients with PsA. We recorded clinical characteristics, as well as protective and risk factors for OP and insufficiency fractures...
January 2024: Reumatología clinica
https://read.qxmd.com/read/38233009/real-world-apremilast-use-in-biologic-na%C3%A3-ve-psoriatic-arthritis-patients-data-from-spanish-clinical-practice
#16
JOURNAL ARTICLE
Jordi Gratacós-Masmitja, Emma Beltrán Catalán, José Luis Álvarez Vega, Ana Urruticoechea-Arana, Concepción Fito, Francisco Maceiras, Joaquín María Belzunegui Otano, Julia Fernández Melón, Eugenio Chamizo Carmona, Miguel Ángel Abad Hernández, Inmaculada Ros Vilamajó, Sonia Castro Oreiro, Eva Pascual Alfonso, Juan Carlos Torre Alonso
INTRODUCTION: Apremilast is approved for treatment of psoriasis and psoriatic arthritis (PsA). Real-world evidence on apremilast effectiveness in clinical practice is limited. METHODS: Observational study enrolling adult patients, across 21 Spanish centres, who had initiated apremilast in the prior 6 (±1) months and were biologic naive. Data were collected at routine follow-up visits 6 and 12 months after apremilast initiation. Primary outcome was 6 and 12-month persistence to apremilast...
January 2024: Reumatología clinica
https://read.qxmd.com/read/38233008/dkk-1-in-psoriatic-arthritis-correlation-with-disease-activity-and-enthesopathy
#17
JOURNAL ARTICLE
Marian Aziz Wahba Abdo Wahba, Nagat Mohamed El-Gazzar, Radwa Mahmoud Elsharaby, Samar Abdalhamed Tabra
BACKGROUND: Psoriatic arthritis (PsA) is a complex inflammatory disease with varied clinical characteristics. A pathognomonic characteristic of PsA is enthesitis. Entheseal inflammation ultimately leads to the production of new bone (enthesophytes). Dickkopf-related protein-1 (DKK-1) is a wingless (Wnt) inhibitor that inhibits osteoblast function. OBJECTIVES: Assessment of the serum level of DKK-1 and its association with disease activity and enthesopathy in PsA patients...
January 2024: Reumatología clinica
https://read.qxmd.com/read/38233007/cxcl10-as-a-biomarker-of-interstitial-lung-disease-in-patients-with-rheumatoid-arthritis
#18
JOURNAL ARTICLE
Yasmine S Makarem, Elzahraa A Ahmed, Marwa Makboul, Shimaa Farghaly, Naima Mostafa, Randa A El Zohne, Samar H Goma
INTRODUCTION: Pulmonary involvement is a frequent and serious rheumatoid arthritis (RA) manifestation that affects 60%-80% of patients. CXCL10 is an inflammatory chemokine that regulates different biological responses, such as chemotaxis, angiogenesis, and inflammation. AIM: This study aimed to identify the role of CXCL10 as a peripheral blood marker of RA-ILD and its correlation with disease activity. PATIENTS AND METHODS: This cross-sectional study included 73 patients with RA (33 with ILD and 40 without ILD)...
January 2024: Reumatología clinica
https://read.qxmd.com/read/38182526/the-patient-journey-of-fibromyalgia-in-latin-america
#19
JOURNAL ARTICLE
Teresa Otón, Osvaldo Daniel Messina, Daniel G Fernández Ávila, Manuel Robles San Román, Darío Mata, Constanza Arguissain, Jorge Miguel Galindo Guzmán, Marina Pérez, Loreto Carmona
OBJECTIVES: To explore the patient journey of people with fibromyalgia (FM) in Latin American countries in order to identify problems in health care and other areas that may be resolvable. METHODS: Qualitative study with phenomenological and content analysis approach through focus groups and patient journey (Ux; User Experience) methodology. Nine virtual focus groups were conducted with FM patients and healthcare professionals in Argentina, Mexico and Colombia recruited from key informants and social networks...
January 4, 2024: Reumatología clinica
https://read.qxmd.com/read/38160120/vexas-syndrome-clinical-manifestations-diagnosis-and-treatment
#20
REVIEW
Michelle Patricia Loeza-Uribe, Andrea Hinojosa-Azaola, Beatriz E Sánchez-Hernández, José C Crispín, Elia Apodaca-Chávez, Marcela A Ferrada, Eduardo Martín-Nares
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) syndrome is an adult-onset autoinflammatory syndrome characterized by somatic mutations in the UBA1 gene and is considered the prototype of hematoinflammatory diseases. Patients with VEXAS syndrome exhibit inflammatory and hematological manifestations that can lead to clinical diagnoses such as relapsing polychondritis, polyarteritis nodosa, Sweet syndrome, and myelodysplastic syndrome. Diagnosis requires bone marrow evaluation to identify cytoplasmic vacuoles in myeloid and erythroid precursors...
December 29, 2023: Reumatología clinica
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