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https://www.readbyqxmd.com/read/29356274/purpose-built-national-burns-center-the-israeli-experience
#1
Hagit Ofir, Hadas Shefler, Rachel Kornhaber, Michelle Cleary, Moti Harats, Josef Haik
The opening of the National Burns Center (NBC) in Sheba Medical Center (SMC) in 2014 was a keystone point in the development of specialized burns trauma services for Israel to ensure burn care and disaster planning at international standards. The NBC is a purpose-built, level 1 burns trauma center that receives patients from Israel, Gaza, West Bank, and abroad. Hosting six intensive care and four step-down burns beds, the center serves as a referral center for patients in other health-care facilities with indication for hospitalization...
January 22, 2018: Nursing & Health Sciences
https://www.readbyqxmd.com/read/29356140/clinicopathological-features-and-course-of-cutaneous-protothecosis
#2
Han-Chi Tseng, Chun-Bing Chen, Ji-Chen Ho, Yu-Wen Cheng, Hsin-Wei Huang, Pei-Lun Sun, Chih-Hung Lee
BACKGROUND: Protothecosis is an uncommon infection caused by the achlorophyllic algae found more commonly in tropical areas. Only a limited number of cases have been reported. OBJECTIVE: We aimed to evaluate the clinicopathological features and treatment outcomes of cutaneous protothecosis. METHODS: We retrospectively identified 20 pathology-confirmed cases of cutaneous protothecosis based on skin biopsies in two tertiary medical centers in Taiwan from 1997 to 2015...
January 22, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29356123/serum-cytokine-profiling-in-cats-with-acute-idiopathic-cystitis
#3
M Parys, V Yuzbasiyan-Gurkan, J M Kruger
BACKGROUND: Feline idiopathic cystitis (FIC) is a common lower urinary tract disorder of domestic cats that resembles interstitial cystitis/painful bladder syndrome (IC/PBS) in humans. Diagnosis of FIC is based on clinical signs and exclusion of other disorders because of a lack of specific pathologic findings or other objective biomarkers. Cytokines are potential noninvasive biomarkers to define the presence, severity, and progression of disease, and response to treatment. OBJECTIVES: The objective of this pilot study was to determine concentrations of selected cytokines in serum from healthy cats and cats with acute FIC...
January 22, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29356061/cohort-study-from-11-european-countries-highlighted-differences-in-the-use-and-efficacy-of-hypothermia-prevention-strategies-after-very-preterm-birth
#4
Emilija Wilson, Jennifer Zeitlin, Aurélie Piedvache, Bjoern Misselwitz, Kyllike Christensson, Rolf F Maier, Mikael Norman, Anna-Karin Edstedt Bonamy
AIM: This study investigated the different strategies used in 11 European countries to prevent hypothermia, which continues to affect a large proportion of preterm births in the region. METHODS: We examined the association between the reported use of hypothermia prevention strategies in delivery rooms and body temperatures on admission to neonatal intensive care units (NICUs) in 5,861 infants born at 22+0 - 31+6 weeks of gestation. The use of plastic bags, wraps, caps, exothermic heat and mattresses was investigated...
January 21, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29355796/clinical-utility-of-serum-procalcitonin-level-and-infection-in-the-neurosurgical-intensive-care-unit
#5
Lauren E Rotman, Bonita S Agee, Gustavo Chagoya, Matthew C Davis, James M Markert
OBJECTIVE: Procalcitonin, a blood stream inflammatory biomarker, has shown to be useful in the diagnosis of sepsis in critically ill patients treated in medical and surgical intensive care units. This study aims to further our understanding of procalcitonin levels in Neuroscience Intensive Care Unit (NICU) patients. METHODS: Neurosurgical patients who underwent procalcitonin assay in the NICU over a two-year period were included. Procalcitonin equal to or above 0...
January 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29355747/proximal-linear-extension-of-skin-hypopigmentation-after-ultrasound-guided-corticosteroid-injection-for-de-quervain-tenosynovitis-a-case-report
#6
Carlo Milani, Cindy Lin
De Quervain tenosynovitis is a stenosing tenosynovitis of the first dorsal compartment of the wrist that can lead to painful functional impairment of the upper limb. This case report describes a rare adverse effect of corticosteroid injection which is local skin atrophy and hypopigmentation with proximal linear extension. In this case, hypopigmentation developed from the wrist to beyond the elbow after corticosteroid injection with ultrasound guidance and targeted placement of the injectate in the extensor tendon sheath of the first dorsal compartment...
January 17, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29355214/informed-consent-in-field-trials-of-gene-drive-mosquitoes
#7
Pamela A Kolopack, James V Lavery
The US National Academies' (NAS) recent report 'Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public Values' examines the requirements of responsible conduct in research involving gene drives in non-human organisms. Many of the complex ethical issues raised by the introduction of gene drive technologies for mosquito population control have been anticipated during the development and field-testing of earlier-generation genetic engineering approaches with mosquitoes...
December 11, 2017: Gates Open Res
https://www.readbyqxmd.com/read/29355173/paradigms-of-acute-kidney-injury-in-the-intensive-care-setting
#8
REVIEW
John A Kellum, John R Prowle
Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies, variable pathogenesis and diverse outcomes. However, these heterogeneities are not reflected in current approaches to the diagnosis and, to some degree, treatment of AKI. For example, congestive heart failure and dehydration can produce identical changes in serum creatinine level and urine output (parameters that are used to define AKI); however, they differ vastly in their physiological contexts and demand completely opposite treatments...
January 22, 2018: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29355141/an-observational-study-of-incidence-risk-factors-outcome-of-systemic-inflammatory-response-organ-dysfunction-following-major-trauma
#9
Satish Balkrishna Dharap, Sanket Vishnu Ekhande
BACKGROUND & OBJECTIVES: Trauma is known to lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS), which is often a cause of late deaths after injury. SIRS and MODS have been objectively measured using scoring systems. This prospective observational study was carried out in a tertiary care hospital in India to evaluate SIRS and MODS following trauma in terms of their incidence, the associated risk factors and the effect on the outcome. METHODS: All adult patients with major life- and limb-threatening trauma were included...
September 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29354777/isolation-and-molecular-characterization-of-cryptococcus-species-isolated-from-pigeon-nests-and-eucalyptus-trees
#10
A Kamari, A Sepahvand, R Mohammadi
Background and Purpose: Cryptococcus species are pathogenic and non-pathogenic basidiomycete yeasts that are found widely in the environment. Based on phenotypic methods, this genus has many species; however, its taxonomy is presently being re-evaluated by modern techniques. The Cryptococcus species complex includes two sibling taxa of Cryptococcus neoformans and Cryptococcus gattii. We aimed to investigate the possible distribution of Cryptococcus species in pigeon nests and Eucalyptus trees in Ilam, Iran, using molecular techniques...
June 2017: Advances in Medical Mycology (Iran)
https://www.readbyqxmd.com/read/29354626/intraoperative-vascular-surgical-consultation-during-non-vascular-surgeries-in-tertiary-centers-by-vascular-surgeon
#11
Sung-Bin Park, Keun-Myoung Park, Yong Sun Jeon, Soon Gu Cho, Kee Chun Hong
Purpose: There are many types of intraoperative consultations by vascular surgeons during non-vascular surgery. Therefore, we examined the current state of intraoperative consultations during non-vascular surgery in a single center. Materials and Methods: From January 2014 to December 2015, we reviewed records of 40 patients (0.3%) who received an intraoperative consultation from a vascular surgeon for 10,734 non-vascular surgeries in Inha University Hospital. We examined patient characteristics, operative details, and clinical results...
December 2017: Vascular Specialist International
https://www.readbyqxmd.com/read/29354572/association-of-post-extubation-dysphagia-with-tongue-weakness-and-somatosensory-disturbance-in-non-neurologic-critically-ill-patients
#12
Hee Seon Park, Jung Hoi Koo, Sun Hong Song
Objective: To prospectively assess the association between impoverished sensorimotor integration of the tongue and lips and post-extubation dysphagia (PED). Methods: This cross-sectional study included non-neurologic critically ill adult patients who required endotracheal intubation and underwent videofluoroscopic swallowing study (VFSS) between October and December 2016. Participants underwent evaluation for tongue and lip performance, and oral somatosensory function...
December 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29354497/current-markers-and-their-value-in-the-era-of-immuno-oncology
#13
REVIEW
Friedrich-Carl von Rundstedt, Andrea Necchi
Immunotherapy in urothelial cancer is a quickly evolving field as new agents are being investigated in multiple clinical trials and various clinical settings. The purpose of this review is to provide an insight into the mechanism of these treatments, potential targets to evaluate treatment response and to give an update on the current status of clinical trials. Urothelial cancer is a polyclonal disease with a substantial tumor heterogeneity and a high mutational load which may be beneficial as this may trigger a stronger T-cell mediated immune response...
December 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29354396/epidemiological-study-on-candida-species-in-patients-with-cancer-in-the-intensive-care-unit
#14
Young-Ju Choi, Byeongyeo Lee, Sun-A Park
Objectives: Although cancer survival rates have increased, serious infection complications can arise in cancer patients. Candida can occur in various tissues and has significant effects on the prognosis of patients with cancer. Thus, we conducted an epidemiological study on Candida infections in patients with cancer admitted to the intensive care unit. Methods: A retrospective study was conducted in adult patients with cancer admitted to the intensive care unit between January 1, 2013, and December 31, 2015...
December 2017: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/29354239/comparative-analysis-of-spontaneous-infectious-spondylitis-pyogenic-versus-tuberculous
#15
Yangwon Lee, Bum-Joon Kim, Se-Hoon Kim, Seung-Hwan Lee, Won-Hyung Kim, Sung-Won Jin
Objective: Spondylitis is often chemotherapy resistant and requires long-term treatment. Without adequate chemotherapy, the outcome can be fatal or result in severe neurologic damage. Therefore, differentiating the etiology of spondylitis is very important, particularly in spontaneous cases. As the prevalence of tuberculosis in Korea has decreased in recent years, updated clinical research about spondylitis is warranted. Methods: From April 2010 to March 2016, data from spondylitis patients were collected retrospectively...
January 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29354178/the-role-of-extracorporeal-membrane-oxygenation-in-patients-after-irreversible-cardiac-arrest-as-potential-organ-donors
#16
REVIEW
Tomasz Kłosiewicz, Mateusz Puślecki, Marcin Zieliński, Michał Mandecki, Marcin Ligowski, Sebastian Stefaniak, Marek Dąbrowski, Marek Karczewski, Łukasz Gąsiorowski, Maciej Sip, Agata Dąbrowska, Wojciech Telec, Bartłomiej Perek, Marek Jemielity
The number of people waiting for a kidney or liver transplant is growing systematically. Due to the latest advances in transplantation, persons after irreversible cardiac arrest and confirmation of death have become potential organ donors. It is estimated that they may increase the number of donations by more than 40%. However, without good organization and communication between pre-hospital care providers, emergency departments, intensive care units and transplantation units, it is almost impossible to save the organs of potential donors in good condition...
December 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29354174/prometheus-therapy-for-the-treatment-of-acute-liver-failure-in-patients-after-cardiac-surgery
#17
Ekaterina Komardina, Michael Yaroustovsky, Marina Abramyan, Marina Plyushch
Introduction: Acute liver failure usually develops in multiple organ dysfunction syndrome and significantly increases the mortality risk in patients after cardiac surgery. Aim: To assess the safety and efficacy of extracorporeal liver support in patients with acute liver failure after cardiac surgery. Material and methods: We studied 39 adult patients with multiple organ dysfunction syndrome and acute liver failure as postoperative complication, treated with Prometheus therapy...
December 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29354009/assessing-the-blood-supply-status-of-the-focal-ground-glass-opacity-in-lungs-using-spectral-computed-tomography
#18
Guanfu Liu, Mengying Li, Guosheng Li, Zhiyong Li, Ailian Liu, Renwang Pu, Huizhi Cao, Yijun Liu
Objective: To exploit material decomposition analysis in dual-energy spectral computed tomography (CT) to assess the blood supply status of the ground-glass opacity (GGO) in lungs. Materials and Methods: This retrospective study included 48 patients with lung adenocarcinoma, who underwent a contrast-enhanced dual-energy spectral CT scan before treatment (53 GGOs in total). The iodine concentration (IC) and water content (WC) of the GGO, the contralateral and ipsilateral normal lung tissues were measured in the arterial phase (AP) and their differences were analyzed...
January 2018: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29353893/organ-dysfunctions-among-deaths-in-critically-ill-patients
#19
Leison Maharjan, Aarzoo Shah, Udaya Bajracharya, Gambhir Shrestha
BACKGROUND: Multiple organ failure is recognized as the final pathway preceding majority of deaths in intensive care unit. This study aims to find out the prevalence of organ dysfunctions/ failures in patients at the time of their demise irrespective of the underlying diseases in a tertiary care hospital. METHODS: This study was done in medical intensive care unit of Blue Cross Hospital. Medical records of all deceased patients in two years period were thoroughly reviewed retrospectively...
January 1, 2018: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/29353710/prevalence-and-predictors-of-difficulty-accessing-the-mouths-of-intubated-critically-ill-adults-to-deliver-oral-care-an-observational-study
#20
Craig M Dale, Orla Smith, Lisa Burry, Louise Rose
BACKGROUND: Oral care of intubated patients is essential to the prevention of infection and patient discomfort. However, barriers to oral access and delivery of oral care have received little attention. OBJECTIVE: To determine prevalence and predictors of oral access difficulty. DESIGN: A prospective, observational, multi-center study. SETTINGS: Four intensive care units in Toronto, Canada. PARTICIPANTS: Adult patients orally intubated for ≥48 h...
December 28, 2017: International Journal of Nursing Studies
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