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goal heart rate in fibrilation

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https://www.readbyqxmd.com/read/28795299/adherence-to-optimal-heart-rate-control-in-heart-failure-with-reduced-ejection-fraction-insight-from-a-survey-of-heart-rate-in-heart-failure-in-sweden-hr-hf-study
#1
M Fu, U Ahrenmark, S Berglund, C J Lindholm, A Lehto, A Månsson Broberg, G Tasevska-Dinevska, G Wikstrom, A Ågard, B Andersson
INTRODUCTION: Despite that heart rate (HR) control is one of the guideline-recommended treatment goals for heart failure (HF) patients, implementation has been painstakingly slow. Therefore, it would be important to identify patients who have not yet achieved their target heart rates and assess possible underlying reasons as to why the target rates are not met. MATERIALS AND METHODS: The survey of HR in patients with HF in Sweden (HR-HF survey) is an investigator-initiated, prospective, multicenter, observational longitudinal study designed to investigate the state of the art in the control of HR in HF and to explore potential underlying mechanisms for suboptimal HR control with focus on awareness of and adherence to guidelines for HR control among physicians who focus on the contributing role of beta-blockers (BBs)...
August 9, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28645513/atrial-fibrillation-current-therapies
#2
REVIEW
Romain Pariaut
A rate control or a rhythm control strategy can be applied to the management of atrial fibrillation. Rate control of atrial fibrillation consists of decreasing the ventricular response rate by limiting the number of supraventricular impulses that can travel through the atrioventricular node. The goal of decreasing heart rate in dogs with atrial fibrillation is usually achieved with a combination of the calcium channel blocker diltiazem and digoxin. Rhythm control of atrial fibrillation encompasses pharmacologic and nonpharmacologic methods to terminate the arrhythmia and restore sinus rhythm...
June 20, 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28624123/population-pharmacokinetic-pharmacodynamics-modeling-of-ibutilide-in-chinese-healthy-volunteers-and-patients-with-atrial-fibrillation-af-and-or-atrial-flutter-afl
#3
Zhijun Zeng, Li Wang, Lu Hua, Juanjuan Jiang, Huimin Pang, Yiling Huang, Yishi Li, Lei Tian
PURPOSE: The goal of this study was to develop a population pharmacokinetic (PK) and PK/pharmacodynamics (PD) model for ibutilide, to evaluate the time course of its effect on QT interval in Chinese. METHODS: The population PK and PK/PD model were developed using data from 40 Chinese healthy volunteers using nonlinear mixed-effects modeling, and the final population PK/PD model was applied on 100 patients with atrial fibrillation (AF) and/or atrial flutter (AFL)...
July 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28386917/epidemiology-and-one-year-outcomes-in-patients-with-chronic-heart-failure-and-preserved-mid-range-and-reduced-ejection-fraction-an-analysis-of-the-esc-heart-failure-long-term-registry
#4
Ovidiu Chioncel, Mitja Lainscak, Petar M Seferovic, Stefan D Anker, Maria G Crespo-Leiro, Veli-Pekka Harjola, John Parissis, Cecile Laroche, Massimo Francesco Piepoli, Candida Fonseca, Alexandre Mebazaa, Lars Lund, Giuseppe A Ambrosio, Andrew J Coats, Roberto Ferrari, Frank Ruschitzka, Aldo P Maggioni, Gerasimos Filippatos
AIMS: The objectives of the present study were to describe epidemiology and outcomes in ambulatory heart failure (HF) patients stratified by left ventricular ejection fraction (LVEF) and to identify predictors for mortality at 1 year in each group. METHODS AND RESULTS: The European Society of Cardiology Heart Failure Long-Term Registry is a prospective, observational study collecting epidemiological information and 1-year follow-up data in 9134 HF patients. Patients were classified according to baseline LVEF into HF with reduced EF [EF <40% (HFrEF)], mid-range EF [EF 40-50% (HFmrEF)] and preserved EF [EF >50% (HFpEF)]...
April 6, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28385080/blood-pressure-control-in-anticoagulated-patients-with-hypertension-and-atrial-fibrillation
#5
Vivencio Barrios, Carlos Escobar, Luis Prieto Valiente, Jose María Lobos, Diego Vargas-Ortega, Jose Polo, Nuria Marin Montañés
OBJECTIVE: To determine the clinical profile and blood pressure (BP) control rates of anticoagulated patients with hypertension and atrial fibrillation (AF). METHODS: The PAULA study was a multicenter cross-sectional/retrospective observational study conducted throughout Spain. The study included patients with nonvalvular AF who were receiving vitamin K antagonist therapy during the past year and were attended at primary care setting. Adequate BP control was defined according to 2013 ESC/ESH guidelines...
April 7, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28138764/-ablation-for-atrial-fibrillation-in-the-elderly
#6
Clemens Jilek, Thorsten Lewalter
Atrial fibrillation is mainly an arrhythmia among the elderly. The current ESC guideline determines that there is no justification to deny atrial fibrillation ablation to any age group; however, the guideline does not provide specific scientific data. Thus, the goal of this article is to summarize the data on efficacy and safety of atrial fibrillation ablation among elderly people and give treatment recommendations: (1) The success of atrial fibrillation ablation is the same between elderly and younger patients...
January 30, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/27993408/antithrombotic-treatment-and-characteristics-of-elderly-patients-with-non-valvular-atrial-fibrillation-hospitalized-at-internal-medicine-departments-nonavasc-registry
#7
Alejandra Gullón, Carmen Suárez, Jesús Díez-Manglano, Francesc Formiga, José María Cepeda, Antonio Pose, Miguel Camafort, Jesús Castiella, Eduardo Rovira, José María Mostaza
BACKGROUND AND OBJETIVES: The prevalence of non-valvular atrial fibrillation (NVAF) increases with the patient's age and is associated with high morbi-mortality rates. The main goal of this study was to describe the characteristics of hospitalized elderly patients with NVAF and to identify the clinical and functional factors which determine the use of different antithrombotic strategies. PATIENTS AND METHODS: Observational, prospective, multicentre study carried out on patients with NVAF over the age of 75, who had been admitted for any medical condition to Internal Medicine departments...
March 3, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/27892888/early-de-novo-atrial-fibrillation-after-coronary-artery-bypass-grafting-facts-and-features
#8
Ameeta Yaksh, Charles Kik, Paul Knops, Maarten J B van Ettinger, Ad J J C Bogers, Natasja M S de Groot
Knowledge of the mechanism underlying post-operative atrial fibrillation (PoAF) is essential for development of preventive measures. The incidence and characteristics of both PoAF and supraventricular premature beats triggering PoAF, their interrelationship and alterations over time have never been examined. The goal of this study is therefore to examine the correlation between the incidence and characteristics of supraventricular premature beats (SVPBs) and PoAF episodes in patients undergoing CABG in the first five post-operative days...
February 2017: American Heart Journal
https://www.readbyqxmd.com/read/27855640/long-term-secondary-prevention-of-acute-myocardial-infarction-sepat-guidelines-adherence-and-outcome
#9
Constantinos Ergatoudes, Erik Thunström, Annika Rosengren, Lena Björck, Kristina Bengtsson Boström, Kristin Falk, Michael Fu
BACKGROUND: A number of registry studies have reported suboptimal adherence to guidelines for cardiovascular prevention during the first year after acute myocardial infarction (AMI). However, only a few studies have addressed long-term secondary prevention after AMI. This study evaluates prevention guideline adherence and outcome of guideline-directed secondary prevention in patients surviving 2 years after AMI. METHODS: Patients aged 18-85 years at the time of their index AMI were consecutively identified from hospital discharge records between July 2010 and December 2011 in Gothenburg, Sweden...
November 17, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27807759/p-wave-dispersion-in-patients-with-guillain-barr%C3%A3-syndrome
#10
Seden Demirci, Akif Arslan, Vedat Ali Yürekli, Süleyman Kutluhan, Hasan Rifat Koyuncuoğlu, Serpil Demirci
Cardiac autonomic dysfunction assessed by the presence of arrhythmia, by the methods, such as heart rate variability or blood pressure variability, and by the electrocardiographic abnormalities is common in Guillain-Barré syndrome (GBS). The goal of present study was to analyze the P-wave dispersion (PWD), which is the non-invasive marker of atrial arrhythmia, in GBS patients and to compare those with healthy individuals. Thirty-five patients with GBS (mean age 53.6 ± 15.5 years) and 35 healthy controls (mean age 49...
March 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/27737407/anticoagulation-quality-and-complications-of-using-vitamin-k-antagonists-in-the-cardiac-surgery-outpatient-clinic
#11
Mário Augusto Cray da Costa, Lucas Kraeski Krum, Juliana da Silva Geraldino, Marcelo Derbli Schafranski, Ricardo Zanetti Gomes, Elise Souza Dos Santos Reis
Introduction: In patients with mechanical prosthetic heart valves or atrial fibrillation requiring anticoagulation to prevent thromboembolic events, several factors influence adherence and anticoagulation complications. Objective: To evaluate the factors that interfere with the quality and complications of anticoagulation with vitamin K antagonists. Methods: A retrospective cohort study of 100 patients, in the period from 2011 to 2014, was performed...
May 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27718051/are-all-people-with-diabetes-and-cardiovascular-risk-factors-or-microvascular-complications-at-very-high-risk-findings-from-the-risk-and-prevention-study
#12
Irene Marzona, Fausto Avanzini, Giuseppe Lucisano, Mauro Tettamanti, Marta Baviera, Antonio Nicolucci, Maria Carla Roncaglioni
AIMS: To verify whether it is possible, in people with diabetes mellitus (DM) considered at very high cardiovascular (CV) risk, stratify this risk better and identify significant modifiable risk factor (including lifestyle habits) to help patients and clinicians improve CV prevention. METHODS: People with DM and microvascular diseases or one or more CV risk factors (hypertension, hyperlipidemia, smoking, poor dietary habits, overweight, physical inactivity) included in the Risk and Prevention study were selected...
February 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/27455121/reducing-false-arrhythmia-alarms-in-the-icu-using-multimodal-signals-and-robust-qrs-detection
#13
Nadi Sadr, Jacqueline Huvanandana, Doan Trang Nguyen, Chandan Kalra, Alistair McEwan, Philip de Chazal
This study developed algorithms to decrease the arrhythmia false alarms in the ICU by processing multimodal signals of photoplethysmography (PPG), arterial blood pressure (ABP), and two ECG signals. The goal was to detect the five critical arrhythmias comprising asystole (ASY), extreme bradycardia (EBR), extreme tachycardia (ETC), ventricular tachycardia (VTA), and ventricular flutter or fibrillation (VFB). The different characteristics of the arrhythmias suggested the application of individual signal processing for each alarm and the combination of the algorithms to enhance false alarm detection...
August 2016: Physiological Measurement
https://www.readbyqxmd.com/read/27170002/activation-of-n-methyl-d-aspartate-receptors-reduces-heart-rate-variability-and-facilitates-atrial-fibrillation-in-rats
#14
Shaobo Shi, Tao Liu, Dandan Wang, Yan Zhang, Jinjun Liang, Bo Yang, Dan Hu
Aims: The goal of this study was to assess the effects of N-methyl-d-aspartate (NMDA) receptors activation on heart rate variability (HRV) and susceptibility to atrial fibrillation (AF). Methods and results: Rats were randomized for treatment with saline, NMDA (agonist of NMDA receptors), or NMDA plus MK-801 (antagonist of NMDA receptors) for 2 weeks. Heart rate variability was evaluated by using implantable electrocardiogram telemeters. Atrial fibrillation susceptibility was assessed with programmed stimulation in isolated hearts...
July 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27076563/atrial-fibrillation-and-atrial-flutter-in-pregnant-women-a-population-based-study
#15
Ming-Sum Lee, Wansu Chen, Zilu Zhang, Lewei Duan, Angie Ng, Hillard T Spencer, Damon M Kwan, Albert Y-J Shen
BACKGROUND: The goal of this study was to determine the prevalence of atrial fibrillation and atrial flutter (AF) in pregnant women and to examine the impact of AF on maternal and fetal outcomes. METHODS AND RESULTS: Between January 1, 2003 and December 31, 2013, there were 264 730 qualifying pregnancies (in 210 356 women) in the Kaiser Permanente Southern California hospitals, among whom AF was noted in 157 pregnancies (129 women; 61.3 per 100 000 women, or 59...
April 13, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/26974002/heart-failure-update-inpatient-management
#16
Ravi Korabathina
Acute decompensated heart failure (HF) is one of most common reasons for hospitalization among individuals older than 65 years. A thorough evaluation, including history, physical examination, and laboratory assessment, is required to optimize care of these patients. In uncertain cases, serum brain-type natriuretic peptide (BNP) or N-terminal proBNP level, stress testing, and/or invasive coronary angiography may be helpful in establishing the diagnosis. The hospital setting provides an opportunity to identify etiologies and stabilize the patient...
March 2016: FP Essentials
https://www.readbyqxmd.com/read/26968666/antiarrhythmic-drug-therapy-for-atrial-fibrillation
#17
REVIEW
Muhammad Rizwan Sardar, Wajeeha Saeed, Peter R Kowey
Atrial fibrillation (AF) is the most frequently encountered arrhythmia. Prevalence increases with advancing age and so as its associated comorbidities, like heart failure. Choice of pharmacologic therapy depends on whether the goal of treatment is maintaining sinus rhythm or tolerating AF with adequate control of ventricular rates. Antiarrhythmic therapy and conversion of AF into sinus rhythm comes with the side effect profile, and we should select best antiarrhythmic therapy, individualized to the patient...
April 2016: Heart Failure Clinics
https://www.readbyqxmd.com/read/26877443/co-10-are-hospitalised-patients-aged-90-years-and-over-treated-well-for-hypertension-lessons-from-a-prospective-survey
#18
J Bohlender, J Nussberger, B Bohlender
BACKGROUND: Hypertension increases dramatically with age. In clinically stable nonagenarians, ESH guidelines would recommend lowering blood pressure (BP) to 140-150mmHg systolic (SBP) and <90mmHg diastolic (DBP) if it is higher, but it is not clear if all of the oldest old comply with or need these goals. We prospectively analysed antihypertensive treatment decisions and BP outcome in a rural primary care hospital. METHODS: All patients aged >89 years with BP medication admitted to the medical ward were prospectively included over 12 months...
December 2015: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/26839043/meta-analysis-of-ivabradine-in-patients-with-stable-coronary-artery-disease-with-and-without-left-ventricular-dysfunction
#19
REVIEW
Carolyn Cammarano, Matthew Silva, Morgan Comee, Jennifer L Donovan, Michael J Malloy
PURPOSE: Ivabradine is a novel If-channel antagonist that controls heart rate and may be helpful in treating patients with left ventricular dysfunction (LVD) who are unable to tolerate β-blockers or achieve a heart rate of 70 beats/min with standard therapy. Three landmark trials were used for the approval of ivabradine in the United States. These trials tested ivabradine in addition to a standard of care (including β-blockers) in patients with stable coronary artery disease (CAD) and found modest benefit in those with established LVD unable to tolerate β-blockers...
February 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/26564592/target-organ-complications-and-cardiovascular-events-associated-with-masked-hypertension-and-white-coat-hypertension-analysis-from-the-dallas-heart-study
#20
Danielle Tientcheu, Colby Ayers, Sandeep R Das, Darren K McGuire, James A de Lemos, Amit Khera, Norman Kaplan, Ronald Victor, Wanpen Vongpatanasin
BACKGROUND: Multiple epidemiological studies from Europe and Asia have demonstrated increased cardiovascular risks associated with isolated elevation of home blood pressure (BP) or masked hypertension (MH). Previous studies have not addressed cardiovascular outcomes associated with MH and white-coat hypertension (WCH) in the general population in the United States. OBJECTIVES: The goal of this study was to determine hypertensive target organ damage and adverse cardiovascular outcomes associated with WCH (high clinic BP, ≥140/90 mm Hg; normal home BP, <135/85 mm Hg), MH (high home BP, ≥135/85 mm Hg; normal clinic BP, <140/90 mm Hg), and sustained hypertension (high home and clinic BP) in the DHS (Dallas Heart Study), a large, multiethnic, probability-based population cohort...
November 17, 2015: Journal of the American College of Cardiology
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