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Abdominal wall reparation

Carmen Ciavarella, Enrico Gallitto, Francesca Ricci, Marina Buzzi, Andrea Stella, Gianandrea Pasquinelli
BACKGROUND: Human mesenchymal stem cells (MSCs) possess well-known reparative abilities, but any defect of the immunomodulatory activity and/or the differentiation process may determine the development of human diseases, including those affecting the vascular wall. MSCs residing within the human aortic wall represent a potential cell mediator of atherosclerotic aneurysm development. METHODS: MSCs isolated from healthy and aneurysm aortas were characterized by flow cytometer and tested for differentiation properties...
April 26, 2017: Stem Cell Research & Therapy
L Ressel, U Hetzel, E Ricci
Veterinary pathologists commonly encounter lesions of blunt trauma. The development of lesions is affected by the object's mass, velocity, size, shape, and angle of impact and by the plasticity and mobility of the impacted organ. Scrape, impact, and pattern abrasions cause localized epidermal loss and sometimes broken hairs and implanted foreign material. Contusions are best identified after reflecting the skin, and must be differentiated from coagulopathies and livor mortis. Lacerations-traumatic tissue tears-may have irregular margins, bridging by more resilient tissue, deviation of the wound tail, crushed hairs, and unilateral abrasion...
September 2016: Veterinary Pathology
Perla Ayala, Jeffrey Caves, Erbin Dai, Layla Siraj, Liying Liu, Ovijit Chaudhuri, Carolyn A Haller, David J Mooney, Elliot L Chaikof
UNLABELLED: A critical challenge in tissue regeneration is to develop constructs that effectively integrate with the host tissue. Here, we describe a composite, laser micromachined, collagen-alginate construct containing human mesenchymal stem cells (hMSCs) for tissue repair applications. Collagen type I was fashioned into laminated collagen sheets to form a mechanically robust fascia that was subsequently laser micropatterned with pores of defined dimension and spatial distribution as a means to modulate mechanical behavior and promote tissue integration...
October 2015: Acta Biomaterialia
Jessica W Crothers, Maryam Zenali
The term Neuromuscular and Vascular Hamartoma (NMVH) was initially coined by Fernando and McGovern in 1982 in their report of 2 cases. Whether this lesion is truly hamartomatous or represents a "burnt-out" phase of varying chronic pathologies has been debated since that time. Examples of NMVH-like proliferations have been reported in the setting of diaphragm disease, Crohn's disease, radiation, and ischemia. Herein we present the case of a 73-year-old female with partial small bowel obstruction and a past surgical history significant for cholecystectomy and abdominal hysterectomy...
December 2015: International Journal of Surgical Pathology
Salvatore Andrea Mastrolia, Edoardo Di Naro, Luca Maria Schonauer, Maria Teresa Loverro, Beatrice Indellicati, Mario Barnaba, Giuseppe Loverro
Vaginal cuff dehiscence is a rare, but potentially morbid, complication of total hysterectomy and refers to separation of the vaginal cuff closure. The term vaginal cuff dehiscence is frequently interchanged with the terms of cuff separation or cuff rupture. All denote the separation of a vaginal incision that was previously closed at time of total hysterectomy. After dehiscence of the vaginal cuff, abdominal or pelvic contents may prolapse through the vaginal opening. Bowel evisceration, outside the vulvar introitus, can lead to serious sequelae, including peritonitis, bowel injury and necrosis, or sepsis...
2014: Case Reports in Obstetrics and Gynecology
Pietro Caglià, Angelo Tracia, Laura Borzì, Luca Amodeo, Lucio Tracia, Massimiliano Veroux, Corrado Amodeo
OBJECTIVE: Ventral incisional hernia is a common complication of abdominal surgery. The marked improvements in medical technology and healthcare, lead to an increasing number of elderly patients to take advantage of even complex surgical procedures. The objective of this literature review was to analyze the risk factors for ventral incisional hernia in elderly patients and to identify measures that might decrease the incidence of this complication. MATERIALS AND METHODS: An analysis of the surgical literature was performed using the search engines EMBASE, Cochrane Library, and PubMed with particular reference to elderly patients using the keywords: abdominal hernia, wound dehiscence, incisional hernia, incidence, trocar site hernia, and hernia prevention...
2014: International Journal of Surgery
Samih S Salama
Cutaneous collagenous vasculopathy (CCV) is a rare distinct idiopathic microangiopathy of the superficial cutaneous vasculature. Seven new cases are reported (6 females and 1 male) ranging in age from 42 to 85 years, with some showing unusual clinical and histopathological findings. All presented with macular telangiectases starting on the lower extremities and spreading progressively in 5 cases and were suspected to have generalized essential telangiectasia. Two cases had a history of over 20 years. One case had lesions in the abdominal striae, and 1 was markedly ecchymotic...
May 2015: American Journal of Dermatopathology
F Podwojewski, M Otténio, P Beillas, G Guérin, F Turquier, D Mitton
The design of meshes for the treatment of incisional hernias could benefit from better knowledge of the mechanical response of the abdominal wall and how this response is affected by the implant. The aim of this study was to characterise the mechanical behaviour of the human abdominal wall. Abdominal walls were tested ex vivo in three states: intact, after creation of a defect simulating an incisional hernia, and after reparation with a mesh implanted intraperitonally. For each state, the abdominal wall was subjected to air pressure loading...
October 2014: Journal of the Mechanical Behavior of Biomedical Materials
Yu M Iriyanov, V F Chernov, S A Radchenko, A V Chernov
The results of clinical and experimental morphological studies of regenerates forming after replacement of large defects of the abdominal wall and tibia with implants from different materials (polytetrafluoroethylene, reperene, prolene, titanium, and titanium nickelide) are analyzed. Study of the regenerate histology and fibroarchitectonics has shown good prospects of mesh constructions from titanium nickelide for effective surgical repair of these defects. The use of this implant seems to be theoretically well-based and promising, particularly under conditions of suppurative infection and low individual reparative regenerative potential...
August 2013: Bulletin of Experimental Biology and Medicine
Pietro Gentile, Gianfranco Marcello Colicchia, Fabio Nicoli, Giulio Cervelli, Cristiano Beniamino Curcio, Lorenzo Brinci, Valerio Cervelli
Management of complex abdominal defects remains a significant challenge for many surgeons, especially in contaminated fields. Currently, available biosynthetic grafts include human cadaveric dermis (AlloDerm), porcine dermal (Permacol and Strattice), and submucosal (Surgisis) sources. All these grafts are composed of an acellular collagen scaffold to provide a bridge for tissue incorporation and neovascularization. The authors describe a case report of a woman who required dual mesh explantation and successive reparative surgery using a porcine dermal matrix for a complex and infected abdominal wound...
December 2013: Surgical Innovation
Bidyut Debnath, Sumitra Kumar Biswas
In cases of giant omphalocele anterior abdominal wall is so poorly developed that primary closure is not possible without excessive tension. The simplest of innovative strategies in such a situation is to provide epithellalisation of sac with secondary closure of ensuing ventral hernia at a later date. Postsurgical chylous ascites is a known entity and it usually responds with supportive therapy. Chylous ascites as a complication of reparative surgery of exomphalos is rare. Here a case of complete resolution of chylous ascites following conservative therapy who underwent a repair of ventral hernia as a sequela to non-operative treatment of giant omphalocele is reported...
August 2010: Journal of the Indian Medical Association
G Campanelli, F Catena, L Ansaloni
The use of nonabsorbable prosthetic materials such as polypropylene, polyester, and ePTFE, have expanded and are now widely used in reparative surgery for abdominal wall hernias.There are still difficulties to find correct indication for prosthetic implant in emergency hernia surgery: as a matter of fact there is still a great debate if to use non-absorbable prostheses in potentially or truly infected operating fields [e.g. after intestinal resections].All these problems can be avoided with the use of absorbable prosthetic materials such as those composed of lactic acid polymers or lactic and glycolic acid copolymers: however, the use of these absorbable prosthesis exposes the patient to a rapid and inevitable hernia recurrence...
2008: World Journal of Emergency Surgery: WJES
Jing Wen, Peiyi Wang, Sumona V Smith, Carolyn A Haller, Elliot L Chaikof
BACKGROUND: The syndecan family of cell surface proteoglycans can bind and modulate the activity of a diverse group of soluble and insoluble ligands, which have been shown to modulate events relevant to acute tissue repair and chronic injury responses. The expression of members of the syndecan family of heparan sulfate proteoglycans during the course of aortic aneurysm formation has not been previously investigated. In this investigation, the spatiotemporal expression of syndecan-1, -2, and -4 was characterized in a murine model of aneurysm formation...
November 2007: Journal of Vascular Surgery
Neusa Margarida Paulo, Flávia Gontijo de Lima, Juarez Távora de Siqueira Júnior, Luiz Fernando Froes Fleury, Fabiano José Ferreira de Sant' Ana, Alinne Cardoso Borges, Thalita da Costa Telles
PURPOSE: To compare seringueira latex membrane implant, with and without polylysine at 0.1% and marlex mesh on the repair of iatrogenic abdominal defects in rats. METHODS: A circular segment block of approximate three centimeters of diameter was sectioned out of the ventral abdominal muscle wall of 31 Wistar rats. The skin was preserved. The animals were divided into three experimental groups: only latex, latex and polylysine at 0.1%, and marlex mesh. Some rats underwent euthanasia at five and some at 120 days after surgery...
July 2005: Acta Cirúrgica Brasileira
R Argirović, I Likić-Ladjević, S Pantović
Investigation has been performed upon 29 patients of average age of 62.7 years who have undergone sacrospinous colpopexy because of different degree of uterovaginal prolapse (26 patients) and vaginal vault prolapse (3 patients) after having abdominal or vaginal hysterectomy. In patients with uterovaginal prolapse, 23 of them have vaginal hysterectomy with high ligation of the enterocele sac, anterior et posterior vaginal repair and sacrospinous colpopexy, while 3 patients had conservation of uterus following previous reparation of vaginal walls and cervicosacrocolpopexy...
2004: Acta Chirurgica Iugoslavica
A A Mehbod, J W Ogilvie, M R Pinto, J D Schwender, E E Transfeldt, K B Wood, J C Le Huec, T Dressel
OBJECTIVE: Vacuum-assisted wound closure (VAC) exposes the wound bed to negative pressure, resulting in removal of edema fluid, improvement of blood supply, and stimulation of cellular proliferation of reparative granulation tissue. It has been used to treat open wounds in the extremities, open sternal wounds, pressure ulcers, and abdominal wall wounds. This study retrospectively reviewed instrumented spine fusions complicated by surgical wound infection and managed by a protocol including the use of VAC in order to evaluate the efficacy of applying vacuum therapy on patients with deep spine infections and exposed instrumentation...
February 2005: Journal of Spinal Disorders & Techniques
D Stojiljković, M Visnjić, S Trenkić, Z Rancić, D Milić, G Stanojević, M Stojiljković, P Kovacević, M Stojanović, G Stevanović
Large defects of abdominal wall (greater than 8 cm in diameter) related to different cause, are still difficult problem of modern surgery. The best results in order to obtain safe and permanent anatomical and functional abdominal wall integrity are reached by autogenous dermal and synthetic grafts. Controversies concerning quality of these procedures are still presents. Our work is based on two equal experimental groups of 20 Vister rats each, with large artificial abdominal wall defects: one treated with autogenous dermal graft, another with synthetic Mersilene mesh graft...
2003: Acta Chirurgica Iugoslavica
Eric H Ledet, Allen L Carl, Darryl J DiRisio, Michael P Tymeson, Lucille B Andersen, Christine E Sheehan, Bhaskar Kallakury, Michael Slivka, Hassan Serhan
BACKGROUND CONTEXT: Destabilization of the lumbar spine results from sacrifice of the anterior longitudinal ligament and disc when removed for graft or cage placement. In a similar fashion, transection of the interspinous ligament during surgical approaches to the posterior spine may result in segmental instability. Such instability can cause abnormal motion or implant migration resulting in a higher incidence of pseudarthrosis. Small intestinal submucosa (SIS) is a naturally occurring extracellular collagen-based matrix, which is derived from porcine small intestine...
May 2002: Spine Journal: Official Journal of the North American Spine Society
N I Slepykh, A A Tret'iakov, A A Stadnikov, S V Petrov
Peculiarities of penetration of living bacterial cultures of Bacillus strain into the structures of the abdominal wall, their positive influence upon the reparative regeneration of surgical wounds were studied in experiments in 240 rats. It was found the living bacterial preparation to be expedient to use as an antagonist of pyogenic infection for purulent postoperative wounds and in order to prevent its development. The clinical antiinflammatory and stimulating the reparative process effects of sporobacterin were studied in 50 patients with infectious wound complications after urgent and scheduled operations...
2003: Vestnik Khirurgii Imeni I. I. Grekova
Koichi Sato, Takeo Maekawa, Kiyotaka Yabuki, Yoshihisa Tamasaki, Hiroshi Maekawa, Keizo Kudo, Hironobu Sengoku, Ikukyo Kawa, Ryo Wada, Michio Matsumoto
We report a 74-year-old man with triple synchronous cancers occurring in the gallbladder, common bile duct, and pancreas. The patient had consulted a nearby physician because of epigastralgia and icterus. On September 30, 1997, the patient was admitted to our department for further evaluation and treatment. Abdominal computed tomography (CT) showed dilatation of the common bile duct, cystic duct, and intrahepatic bile duct, and swelling of the gallbladder. On CT, the wall of the distal common bile duct was thick and a low-density mass was detected on the left side...
2003: Journal of Gastroenterology
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