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https://www.readbyqxmd.com/read/29656848/the-discipline-of-epidemiology-engaging-in-the-full-breadth-of-population-health-science
#1
Harold I Feldman
This address was delivered by Harold I. Feldman, MD, MSCE, at the Annual Meeting of the American College of Epidemiology in New Orleans, Louisiana, on September 26, 2017. Dr. Feldman is George S. Pepper Professor of Public Health and Preventive Medicine, Professor of Epidemiology and Medicine, and Chair, Department of Biostatistics, Epidemiology, and Informatics at the Perelman School of Medicine at the University of Pennsylvania. He is recognized nationally and internationally for his expertise in kidney disease epidemiology...
June 2018: Annals of Epidemiology
https://www.readbyqxmd.com/read/29529988/on-the-shoulders-of-giants-the-story-behind-the-pioneers-of-nephrology-project
#2
EDITORIAL
Giorgina B Piccoli, Bernard G Jaar, Hayley Henderson
This editorial introduces a series of interviews with the pioneers of Nephrology. It's a story that speaks by itself, given the thousands of people that are now alive thanks to the remarkable advances in renal replacement therapies such as dialysis, and kidney transplantation but also the many scientific advances in our understanding of the pathophysiology and treatment of kidney diseases worldwide.The interviews that we have selected for this series are, however, not dealing with their achievements, and their success; they try to pass on to future generations the idea of how they were, why they were passionate, what they loved, and, not last, where they found poetry in our profession...
March 12, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29479427/enhancing-outpatient-nephrology-experience-for-internal-medicine-residents
#3
Varun Agrawal, Kenar D Jhaveri, Hitesh H Shah
Interest in nephrology careers continues to remain low in the USA. Educational innovations that enhance interest in nephrology among medical trainees are being actively studied. While internal medicine (IM) residency programs commonly offer the inpatient nephrology elective to the resident, outpatient nephrology experience is lacking. Understanding the provision of care in outpatient and home dialysis and management of patients with glomerular diseases, chronic kidney disease and kidney transplantation are vital components of an outpatient nephrology rotation...
August 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29181500/perinatal-diagnosis-management-and-follow-up-of-cystic-renal-diseases-a-clinical-practice-recommendation-with-systematic-literature-reviews
#4
Charlotte Gimpel, Fred E Avni, Carsten Bergmann, Metin Cetiner, Sandra Habbig, Dieter Haffner, Jens König, Martin Konrad, Max C Liebau, Lars Pape, Georg Rellensmann, Andrea Titieni, Constantin von Kaisenberg, Stefanie Weber, Paul J D Winyard, Franz Schaefer
Importance: Prenatal and neonatal cystic kidney diseases are a group of rare disorders manifesting as single, multiple unilateral, or bilateral cysts or with increased echogenicity of the renal cortex without macroscopic cysts. They may be accompanied by grossly enlarged kidneys, renal oligohydramnios, pulmonary hypoplasia, extrarenal abnormalities, and neonatal kidney failure. The prognosis is extremely variable from trivial to very severe or even uniformly fatal, which poses significant challenges to prenatal counseling and management...
January 1, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/28435157/the-systemic-nature-of-ckd
#5
REVIEW
Carmine Zoccali, Raymond Vanholder, Ziad A Massy, Alberto Ortiz, Pantelis Sarafidis, Friedo W Dekker, Danilo Fliser, Denis Fouque, Gunnar H Heine, Kitty J Jager, Mehmet Kanbay, Francesca Mallamaci, Gianfranco Parati, Patrick Rossignol, Andrzej Wiecek, Gerard London
The accurate definition and staging of chronic kidney disease (CKD) is one of the major achievements of modern nephrology. Intensive research is now being undertaken to unravel the risk factors and pathophysiologic underpinnings of this disease. In particular, the relationships between the kidney and other organs have been comprehensively investigated in experimental and clinical studies in the last two decades. Owing to technological and analytical limitations, these links have been studied with a reductionist approach focusing on two organs at a time, such as the heart and the kidney or the bone and the kidney...
June 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/26709063/conservative-care-of-the-elderly-ckd-patient-a-practical-guide
#6
REVIEW
Divya Raghavan, Jean L Holley
Palliative care is a branch of medicine dedicated to the relief of symptoms experienced during the course of illness. Renal palliative medicine or kidney supportive care is an evolving branch of nephrology, which incorporates the principles of palliative care into the care of CKD and ESRD (dialysis, transplant, and conservatively managed) patients. Conservative (non-dialytic) management is a legitimate option for frail, elderly CKD patients in whom dialysis may not lead to an improvement in quality or duration of life...
January 2016: Advances in Chronic Kidney Disease
https://www.readbyqxmd.com/read/26430515/assessing-the-extent-to-which-current-clinical-research-is-consistent-with-patient-priorities-a-scoping-review-using-a-case-study-in-patients-on-or-nearing-dialysis
#7
Min Jun, Braden Manns, Andreas Laupacis, Liam Manns, Bhavdeep Rehal, Sally Crowe, Brenda R Hemmelgarn
PURPOSE OF REVIEW: There is growing acknowledgement that engaging patients to identify their research priorities is important. Using a case study of patients on or nearing dialysis, we sought to assess the extent to which recently completed and ongoing clinical research was consistent with priorities identified by patients, caregivers, and clinicians. SOURCES OF INFORMATION: Over a 4-year sampling frame (January 2010 to December 2013), we systematically searched the medical literature (top 5 nephrology and top 10 general medicine journals accessed through MEDLINE via Ovid), international randomized controlled trial (RCT) registries, and national government and kidney research funding organizations (Canada, U...
2015: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/26276141/nephrologists-as-educators-clarifying-roles-seizing-opportunities
#8
Kenar D Jhaveri, Mark A Perazella
Nephrologists play an important role in providing medical education in a variety of settings, including the medical school classroom, nephrology consult service, outpatient clinic, and dialysis unit. Therefore, nephrologists interact with a variety of learners. In this article the current state of published literature in medical education in nephrology is reviewed. Eight attending roles are identified of the nephrologist as a medical educator in the academic settings: inpatient internal medicine service, nephrology inpatient consult service, inpatient ESRD service, outpatient nephrology clinic, kidney transplantation, dialysis unit, classroom teacher, and research mentor...
January 7, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/26093884/complementary-and-alternative-medicine-use-among-patients-with-chronic-kidney-disease-and-kidney-transplant-recipients
#9
Noha A Osman, Safaa M Hassanein, Marwa M Leil, Mohamed M NasrAllah
OBJECTIVE: To explore and compare complementary and alternative medicine (CAM) practice among subsets of patients with chronic kidney disease (CKD) and renal allograft recipients. DESIGN: Cross-sectional survey questionnaire. SETTING: Three outpatient nephrology clinics and dialysis centers in Egypt. SUBJECTS: A total of 1005 subjects were included in the study (560 predialyis patients with CKD 3-4, 245 patients on hemodialysis, and 200 transplant recipients)...
November 2015: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/26012163/-treatment-of-anemia-in-chronic-kidney-disease-position-statement-of-the-croatian-society-for-nephrology-dialysis-and-transplantation-and-review-of-the-kdigo-and-erpb-guidelines
#10
Sanjin Rački, Nikolina Bašić-Jukić, Petar Kes, Dragan Ljutić, Vesna Lovčić, Ingrid Prkačin, Josipa Radić, Božidar Vujičić, Ivan Bubić, Marko Jakić, Žarko Belavić, Siniša Sefer, Mario Pehai, Dragan Klarić, Marijana Gulin
Renal anemia is the result of chronic kidney disease (CKD) and deteriorates with disease progression. Anemia may be the first sign of kidney disease. In all patients with anemia and CKD, diagnostic evaluation is required. Prior to diagnosing renal anemia, it is necessary to eliminate the other possible causes. Direct correlation between the concentration of hemoglobin and the stage of renal failure is well known. Early development of anemia is common in diabetic patients. Correction of anemia may slow the progression of CKD...
April 2014: Acta Medica Croatica: C̆asopis Hravatske Akademije Medicinskih Znanosti
https://www.readbyqxmd.com/read/26012162/-consensus-statement-of-the-croatian-society-for-nephrology-dialysis-and-transplantation-regarding-the-use-of-generic-immunosuppressive-drugs
#11
Nikolina Bašić-Jukić, Sanjin Rački, Mladen Knotek, Ljubica Bubić-Filipi, Ivan Bubić, Lada Zibar, Petar Kes
The use of generic immunosuppressive drugs may decrease the cost of immunosuppressive medication, although total cost sav- ings are still a matter of debate since patients need close monitoring after conversion from original to the generic formulation. A working group of the Croatian Society of Transplantation was established to develop recommendations on the use of generic immunosuppression in renal transplant recipients based on a review of the available data. Immunosuppressive drugs belong to the 'narrow therapeutic index' drugs, with huge pharmacokinetic variations secondary to the impact of food, other drugs, as well as of kidney and liver function...
April 2014: Acta Medica Croatica: C̆asopis Hravatske Akademije Medicinskih Znanosti
https://www.readbyqxmd.com/read/26012159/-how-to-prevent-protein-energy-wasting-in-patients-with-chronic-kidney-disease-position-statement-of-the-croatian-society-of-nephrology-dialysis-and-transplantation
#12
Nikolina Bašić-Jukić, Sanjin Rački, Petar Kes, Dragan Ljutić, Bozidar Vujičić, Vesna Lovčić, Lidija Orlić, Ingrid Prkačin, Josipa Radić, Marko Jakić, Dragan Klarić, Marijana Gulin
Protein-energy wasting (PEW) is a frequent problem in patients with end-stage renal disease, which is associated with adverse outcome. Risk factors for development of PEW in dialysis patients include anorexia, limitations in food intake due to problems with mineral metabolism (hyperphosphatemia, hyperkalemia). Prevention of PEW in dialysis population demands different therapeutic measures to correct abnormalities and to prevent loss of energy and proteins. Therapeutic approach should be individualized based on the specific problems of each patient in order to correct metabolic problems and to optimize food intake...
April 2014: Acta Medica Croatica: C̆asopis Hravatske Akademije Medicinskih Znanosti
https://www.readbyqxmd.com/read/25894169/the-role-of-a-single-center-experience-in-azerbaijan-s-nephrology-field
#13
Hikmet Ismayilov, Shahin Qadimov, Kamil Muslumov, Khanbaba Huseynov, Fariz Babayev
OBJECTIVES: There is a saying that, to evaluate the level of medicine in a country, one should pay attention to its level of uronephrology service - specifically, the level of renal replacement therapy, hemodialysis, peritoneal dialysis, and transplant. With the increasing number of patients requiring renal replacement therapy, it is the utmost duty of modern medicine to structure and organize it. Since its establishment in 2000, MedServis Private Medical Centre has dedicated its main services to hemodialysis, renal replacement therapy, health care in other branches of medicine, follow-ups, and preparing patients for transplant...
April 2015: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/25258667/renal-stem-cell-reprogramming-prospects-in-regenerative-medicine
#14
REVIEW
Elvin E Morales, Rebecca A Wingert
Stem cell therapy is a promising future enterprise for renal replacement in patients with acute and chronic kidney disease, conditions which affect millions worldwide and currently require patients to undergo lifelong medical treatments through dialysis and/or organ transplant. Reprogramming differentiated renal cells harvested from the patient back into a pluripotent state would decrease the risk of tissue rejection and provide a virtually unlimited supply of cells for regenerative medicine treatments, making it an exciting area of current research in nephrology...
September 26, 2014: World Journal of Stem Cells
https://www.readbyqxmd.com/read/25193732/telemedicine-as-an-ethics-teaching-tool-for-medical-students-within-the-nephrology-curriculum
#15
Katrina A Bramstedt, Melissa Prang, Sameer Dave, Paul Ng Hung Shin, Amani Savy, Richard A Fatica
A novel patient-centered approach was used to deliver ethics curriculum to medical students. Two medical school clinicians designed a telemedicine session linking their facilities (across 2 continents). The session, Exploring the Patient Experience Through Telemedicine: Dialysis and End-Stage Renal Disease, allowed second-year medical students to explore various parameters of quality of life experienced by dialysis patients. A panel of 4 medical students interviewed a dialysis patient via Skype video connection between the medical school and the hospital's dialysis unit...
September 2014: Progress in Transplantation
https://www.readbyqxmd.com/read/24569496/clinical-practice-guideline-on-diagnosis-and-treatment-of-hyponatraemia
#16
Goce Spasovski, Raymond Vanholder, Bruno Allolio, Djillali Annane, Steve Ball, Daniel Bichet, Guy Decaux, Wiebke Fenske, Ewout J Hoorn, Carole Ichai, Michael Joannidis, Alain Soupart, Robert Zietse, Maria Haller, Sabine van der Veer, Wim Van Biesen, Evi Nagler
Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms, from subtle to severe or even life threatening, and is associated with increased mortality, morbidity and length of hospital stay in patients presenting with a range of conditions. Despite this, the management of patients remains problematic. The prevalence of hyponatraemia in widely different conditions and the fact that hyponatraemia is managed by clinicians with a broad variety of backgrounds have fostered diverse institution- and speciality-based approaches to diagnosis and treatment...
April 2014: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/24569125/clinical-practice-guideline-on-diagnosis-and-treatment-of-hyponatraemia
#17
Goce Spasovski, Raymond Vanholder, Bruno Allolio, Djillali Annane, Steve Ball, Daniel Bichet, Guy Decaux, Wiebke Fenske, Ewout J Hoorn, Carole Ichai, Michael Joannidis, Alain Soupart, Robert Zietse, Maria Haller, Sabine van der Veer, Wim Van Biesen, Evi Nagler
Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms, from subtle to severe or even life threatening, and is associated with increased mortality, morbidity and length of hospital stay in patients presenting with a range of conditions. Despite this, the management of patients remains problematic. The prevalence of hyponatraemia in widely different conditions and the fact that hyponatraemia is managed by clinicians with a broad variety of backgrounds have fostered diverse institution- and speciality-based approaches to diagnosis and treatment...
March 2014: European Journal of Endocrinology
https://www.readbyqxmd.com/read/24552851/kdigo-clinical-practice-guideline-for-lipid-management-in-ckd-summary-of-recommendation-statements-and-clinical-approach-to-the-patient
#18
REVIEW
Christoph Wanner, Marcello Tonelli
The Kidney Disease: Improving Global Outcomes (KDIGO) organization developed clinical practice guidelines on lipid management for all adults and children with chronic kidney disease (CKD). Thirteen recommendations were obtained from the available evidence outlining a three-step management including assessment in all, treatment in many, and follow-up measurements in few. A key element is the recommendation of statin or statin/ezetimibe treatment in adults aged ⩾50 years with estimated glomerular filtration rate (eGFR) <60 ml/min per 1...
June 2014: Kidney International
https://www.readbyqxmd.com/read/24335189/beyond-linear-methods-of-data-analysis-time-series-analysis-and-its-applications-in-renal-research
#19
REVIEW
Ashwani K Gupta, Andreea Udrea
Analysis of temporal trends in medicine is needed to understand normal physiology and to study the evolution of disease processes. It is also useful for monitoring response to drugs and interventions, and for accountability and tracking of health care resources. In this review, we discuss what makes time series analysis unique for the purposes of renal research and its limitations. We also introduce nonlinear time series analysis methods and provide examples where these have advantages over linear methods. We review areas where these computational methods have found applications in nephrology ranging from basic physiology to health services research...
2013: Nephron. Physiology
https://www.readbyqxmd.com/read/24175235/what-is-the-purpose-of-launching-the-world-journal-of-nephrology
#20
Anil K Mandal
The launch of the World Journal of Nephrology (WJN) has distinct purposes. Its main purpose is to incorporate the fields of diabetes, hypertension, urology, cardiology and neurology, which are related to kidney disease, and to make all of our readers, contributors and allied health professionals feel at home with the WJN. The WJN aims to rapidly report new theories, methods and techniques for prevention, diagnosis, treatment, rehabilitation and nursing skill in the field of nephrology. The WJN will cover diagnostic imaging, disorders of kidney development, renal obstruction, atrophy and regeneration, kidney tumors, renal pharmacology and therapy, renal replacement therapies including transplantation, and Chinese herbal medicine...
February 6, 2012: World Journal of Nephrology
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