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https://www.readbyqxmd.com/read/28530486/y-balance-test-performance-following-a-competitive-field-hockey-season-a-pretest-posttest-study
#1
Matthew C Hoch, Lauren A Welsch, Emily M Hartley, Cameron J Powden, Johanna M Hoch
CONTEXT: The Y-Balance Test (YBT) is a dynamic balance assessment used as a preseason musculoskeletal screen to determine injury risk. While the YBT has demonstrated excellent test-retest reliability, it is unknown if YBT performance changes following participation in a competitive athletic season. OBJECTIVE: Determine if a competitive athletic season affects YBT performance in field hockey players. DESIGN: Pretest-posttest. SETTING: Laboratory...
May 22, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28525340/detection-of-bordetella-avium-by-taqman-real-time-pcr-in-tracheal-swabs-from-wildlife-birds
#2
T Stenzel, D Pestka, B Tykałowski, M Śmiałek, A Koncicki, A Bancerz-Kisiel
Bordetella avium, the causing agent of bordetellosis, a highly contagious infection of the respiratory tract in young poultry, causes significant losses in poultry farming throughout the world. Wildlife birds can be a reservoir of various pathogens that infect farm animals. For this reason the studies were conducted to estimate the prevalence of Bordetella avium in wildlife birds in Poland. Tracheal swab samples were collected from 650 birds representing 27 species. The bacterial DNA was isolated directly from the swabs and screened for Bordetella avium by TaqMan real-time PCR...
March 28, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28515975/prospective-functional-performance-testing-and-relationship-to-lower-extremity-injury-incidence-in-adolescent-sports-participants
#3
Joseph Smith, Nick DePhillipo, Iris Kimura, Morgan Kocher, Ronald Hetzler
BACKGROUND: Due to the high number of adolescent athletes and subsequent lower extremity injuries, improvements of injury prevention strategies with emphasis on clinic-based and practical assessments are warranted. PURPOSE: The purpose of this study was to prospectively investigate if a battery of functional performance tests (FPT) could be used as a preseason-screening tool to identify adolescent athletes at risk for sports-related acute lower extremity injury via comparison of injured and uninjured subjects...
April 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28515725/application-of-zebrafish-models-in-inflammatory-bowel-disease
#4
REVIEW
Li Hanyang, Liu Xuanzhe, Chen Xuyang, Qiu Yujia, Fu Jiarong, Shen Jun, Ran Zhihua
Inflammatory bowel disease (IBD) is a chronic, recurrent, and remitting inflammatory disease with unclear etiology. As a clinically frequent disease, it can affect individuals throughout their lives, with multiple complications. Unfortunately, traditional murine models are not efficient for the further study of IBD. Thus, effective and convenient animal models are needed. Zebrafish have been used as model organisms to investigate IBD because of their suggested highly genetic similarity to humans and their superiority as laboratory models...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28515302/transposon-mutagenesis-of-the-zika-virus-genome-highlights-regions-essential-for-rna-replication-and-restricted-for-immune-evasion
#5
Benjamin O Fulton, David Sachs, Megan C Schwarz, Peter Palese, Matthew J Evans
The molecular constraints affecting Zika virus (ZIKV) evolution are not well understood. To investigate ZIKV genetic flexibility, we used transposon mutagenesis to add 15-nucleotide insertions throughout the MR766 ZIKV genome and subsequently deep sequenced the viable mutants. Few ZIKV insertion mutants replicated, which likely reflects a high degree of functional constraints on the genome. The NS1 gene exhibited distinct mutational tolerances at different stages of the screen. This result may define regions of the NS1 protein that are required for the different stages of the viral life cycle...
May 17, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28515108/a-comparison-of-the-natural-history-of-hpv-infection-and-cervical-abnormalities-among-hiv-positive-and-hiv-negative-women-in-senegal-africa
#6
Hilary K Whitham, Stephen E Hawes, Haitao Chu, J Michael Oakes, Alan R Lifson, Nancy B Kiviat, Papa Salif Sow, Geoffrey S Gottlieb, Selly Ba, Marie P Sy, Shalini L Kulasingam
Background: There is evidence of an interaction between HIV and human papillomavirus (HPV) resulting in increased HPV-associated morbidity and cancer mortality among HIV-positive women. This study aims to determine how the natural history of cervical HPV infection differs by HIV status.Methods: A total of 1,320 women (47% were positive for HIV-1 and/or HIV-2) were followed for an average of two years in Senegal, West Africa between 1994 and 2010. Cytology (with a sub-sample of histology) and HPV DNA testing were performed at approximately 4-month intervals yielding data from over 7,900 clinic visits...
May 17, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28514994/active-syphilis-and-its-association-with-hiv-and-sexual-risk-behaviours-in-a-multicity-sample-of-men-who-have-sex-with-men-and-transgender-women-in-peru
#7
Lia N Pizzicato, Panagiotis Vagenas, Pedro Gonzales, Javier R Lama, Monica Pun, Jorge Sanchez, Frederick L Altice
Background: Syphilis in Peru is heavily concentrated in men who have sex with men (MSM) and transgender women (TGW). The aim of the present study was to understand the risk factors for active syphilis infection among MSM and TGW in Peru. Methods: Independent correlates suggestive of active syphilis infection were examined to better understand risk factors for syphilis in MSM and TGW, with separate analyses conducted based on location and among TGW. In 2011, 5101 MSM and TGW completed both self-report surveys and HIV and syphilis testing in five Peruvian cities...
May 18, 2017: Sexual Health
https://www.readbyqxmd.com/read/28511454/the-factor-structure-and-psychometric-properties-of-the-persian-version-of-the-revised-prenatal-coping-inventory-nu-pci
#8
Mahbobeh Faramarzi, Hajar Pasha, Sorayya Khafri, Shima Heidary
INTRODUCTION: Familiarity with coping strategies is essential for stress management during pregnancy. The Revised Prenatal Coping Inventory (Nu-PCI) was developed to assess coping strategies during pregnancy. AIM: This study aimed to assess the factor structure and psychometric properties of the Persian version of the Nu-PCI. MATERIALS AND METHODS: After forward-backward translation, the Nu-PCI was administered to 210 pregnant women who were enrolled in two teaching referral clinics in the North of the Islamic Republic of Iran (Babol)...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28505345/cardio-oncology-a-multidisciplinary-approach-for-detection-prevention-and-management-of-cardiac-dysfunction-in-cancer-patients
#9
Kazuko Tajiri, Kazutaka Aonuma, Ikuo Sekine
Cardiac dysfunction that develops during or after completion of cancer therapy is a growing health concern that should be addressed in a multidisciplinary setting. Cardio-oncology is a new discipline that focuses on screening, monitoring and treating cardiovascular disease during and after cancer treatment. A baseline cardiovascular risk assessment is essential. For high-risk patients, a tailored and detailed plan for cardiovascular management throughout treatment and beyond should also be established. Anthracycline and/or trastuzumab-containing chemotherapy and chest-directed radiation therapy are well known cardiotoxic cancer therapies...
May 15, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28502793/salt-mediated-oligomerization-of-the-mouse-prion-protein-monitored-by-real-time-nmr
#10
Ishita Sengupta, Suhas H Bhate, Ranabir Das, Jayant B Udgaonkar
The prion protein forms ß-rich soluble oligomers in vitro at pH4 in the presence of physiological concentrations of salt. In the absence of salt, oligomerization and misfolding does not take place in an experimentally tractable timescale. While it is well established that a lowering of pH facilitates misfolding and oligomerization of this protein, the role of salt remains poorly understood. Here, solution-state NMR was used to probe perturbations in the monomeric mouse prion protein moPrP) structure immediately upon salt-addition, prior to the commencement of the oligomerization reaction...
May 11, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28500978/novel-polyglycerol-dioleate-based-cubosomal-dispersion-with-tailored-physical-characteristics-for-controlled-delivery-of-ondansetron
#11
M Mansour, A O Kamel, S Mansour, N D Mortada
In this study different amphiphilic lipids viz. glycerylmonooleate (GMO), Glycerylmonolinoleate (GML), Plurol(®) (polyglycerol 3-dioleate), Soya phosphatidylcholine (Soya PC), Dipalmitoyl-phosphatidylcholine (DPPC) and Dipalmitoyl- phosphatidylglycerol (DPPG) were screened for their ability to form cubosomes and the formed particles were optimized for controlled delivery using ondansetron as a model drug. Polarized optical microscopy and high resolution transmission electron microscopy were performed to investigate the morphology of the prepared particles...
April 26, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28497697/synthetic-protein-scaffolds-for-biosynthetic-pathway-colocalization-on-lipid-droplet-membranes
#12
Jyun-Liang Lin, Jie Zhu, Ian Wheeldon
Eukaryotic biochemistry is organized throughout the cell in and on membrane-bound organelles. When engineering metabolic pathways this organization is often lost, resulting in flux imbalance and a loss of kinetic advantages from enzyme colocalization and substrate channeling. Here, we develop a protein-based scaffold for colocalizing multienzyme pathways on the membranes of intracellular lipid droplets. Scaffolds based on the plant lipid droplet protein oleosin and cohesin-dockerin interaction pairs recruited upstream enzymes in yeast ester biosynthesis to the native localization of the terminal reaction step, alcohol-O-acetyltransferase (Atf1)...
May 23, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28491121/development-of-a-new-heat-tolerance-assay-system-for-rice-spikelet-sterility
#13
Makoto Hakata, Hiroshi Wada, Chisato Masumoto-Kubo, Ryo Tanaka, Hiroyuki Sato, Satoshi Morita
BACKGROUND: Reduction in rice yield caused by high temperature-induced spikelet sterility has been a serious concern in rice production. To date, several screening methods have been used, although their reproducibility is sometimes poor due to artifacts mainly caused by varietal differences in heading dates and panicle heights (i.e., the distance from the lamps). METHODS: We have developed a novel assay system for heat-induced spikelet sterility by using artificial rice paddies in phytotrons to conduct a highly reproducible assay throughout a year...
2017: Plant Methods
https://www.readbyqxmd.com/read/28488858/development-of-a-high-throughput-ion-exchange-resin-characterization-workflow
#14
Chun Liu, Daniel Dermody, Keith Harris, Thomas Boomgaard, Jeff Sweeney, Daryl Gisch, Bob Goltz
A novel high-throughout (HTR) ion-exchange (IEX) resin workflow has been developed for characterizing ion exchange equilibrium of commercial and experimental IEX resins against a range of different applications where water environment differs from site to site. Because of its much higher throughput, design of experiment (DOE) methodology can be easily applied for studying the effects of multiple factors on resin performance. Two case studies will be presented to illustrate the efficacy of the combined HTR workflow and DOE method...
May 18, 2017: ACS Combinatorial Science
https://www.readbyqxmd.com/read/28487711/in-silico-identification-of-mimicking-molecules-as-defense-inducers-triggering-jasmonic-acid-mediated-immunity-against-alternaria-blight-disease-in-brassica-species
#15
Rajesh K Pathak, Mamta Baunthiyal, Rohit Shukla, Dinesh Pandey, Gohar Taj, Anil Kumar
Alternaria brassicae and Alternaria brassicicola are two major phytopathogenic fungi which cause Alternaria blight, a recalcitrant disease on Brassica crops throughout the world, which is highly destructive and responsible for significant yield losses. Since no resistant source is available against Alternaria blight, therefore, efforts have been made in the present study to identify defense inducer molecules which can induce jasmonic acid (JA) mediated defense against the disease. It is believed that JA triggered defense response will prevent necrotrophic mode of colonization of Alternaria brassicae fungus...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28486502/mir-376c-promotes-carcinogenesis-and-serves-as-a-plasma-marker-for-gastric-carcinoma
#16
Pei-Shih Hung, Chin-Yau Chen, Wei-Ting Chen, Chen-Yu Kuo, Wen-Liang Fang, Kuo-Hung Huang, Peng-Chih Chiu, Su-Shun Lo
Gastric carcinoma is highly prevalent throughout the world. Understanding the pathogenesis of this disease will benefit diagnosis and resolution. Studies show that miRNAs are involved in the tumorigenesis of gastric carcinoma. An initial screening followed by subsequent validation identified that miR-376c is up-regulated in gastric carcinoma tissue and the plasma of patients with the disease. In addition, the urinary level of miR-376c is also significantly increased in gastric carcinoma patients. The plasma miR-376c level was validated as a biomarker for gastric carcinoma, including early stage tumors...
2017: PloS One
https://www.readbyqxmd.com/read/28483308/travel-times-for-screening-mammography-impact-of-geographic-expansion-by-a-large-academic-health-system
#17
Andrew B Rosenkrantz, Yu Liang, Richard Duszak, Michael P Recht
RATIONALE AND OBJECTIVES: This study aims to assess the impact of off-campus facility expansion by a large academic health system on patient travel times for screening mammography. MATERIALS AND METHODS: Screening mammograms performed from 2013 to 2015 and associated patient demographics were identified using the NYU Langone Medical Center Enterprise Data Warehouse. During this time, the system's number of mammography facilities increased from 6 to 19, reflecting expansion beyond Manhattan throughout the New York metropolitan region...
May 5, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28482828/health-beliefs-illness-perceptions-and-determinants-of-breast-screening-uptake-in-malta-a-cross-sectional-survey
#18
Danika Marmarà, Vincent Marmarà, Gill Hubbard
BACKGROUND: Women's beliefs and representations of breast cancer (BC) and breast screening (BS) are salient predictors for BS practices. This study utilized the health belief model (HBM) and common-sense model (CSM) of illness self-regulation to explore factors associated with BS uptake in Malta and subsequently, to identify the most important predictors to first screening uptake. METHODS: This cross-sectional survey enrolled Maltese women (n = 404) ages 50 to 60 at the time of their first screening invitation, invited to the National Breast Screening Programme by stratified random sampling, with no personal history of BC...
May 8, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28476101/community-based-randomized-controlled-trial-of-diabetes-prevention-study-for-high-risk-individuals-of-type-2-diabetes-lifestyle-intervention-using-web-based-system
#19
Seon-Ah Cha, Sun-Young Lim, Kook-Rye Kim, Eun-Young Lee, Borami Kang, Yoon-Hee Choi, Kun-Ho Yoon, Yu-Bae Ahn, Jin-Hee Lee, Seung-Hyun Ko
BACKGROUND: The trend of increasing numbers of patients with type 2 diabetes emphasizes the need for active screening of high-risk individuals and intensive lifestyle modification (LSM). METHODS/DESIGN: The community-based Korean Diabetes Prevention Study (C-KDPS) is a randomized controlled clinical trial to prevent type 2 diabetes by intensive LSM using a web-based program. The two public healthcare centers in Korea are involved, and 420 subjects are being recruited for 6 months and will be followed up for 22 months...
May 5, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28466563/immunohistochemical-profiling-of-the-ultimobranchial-remnants-in-the-rat-postnatal-thyroid-gland
#20
Victoria Vázquez-Román, José C Utrilla, José M Fernández-Santos, Inés Martín-Lacave
Ultimobranchial (UB) remnants are a constant presence in the thyroid throughout rat postnatal life; however, the difficulty in identifying the most immature forms from the surrounding thyroid tissue prompted us to search for a specific marker. With that objective, we applied a panel of antibodies reported to be specific for their human counterpart, solid cell nests (SCNs), using double immunohistochemistry and immunofluorescence. Our results demonstrated that cytokeratin 34βE12 and p63 are highly sensitive markers for the immunohistologic screening of UB-remnants, independently of their maturity or size...
May 2, 2017: Journal of Morphology
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