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https://www.readbyqxmd.com/read/27910424/a-study-of-cr-39-plastic-charged-particle-detector-replacement-by-consumer-imaging-sensors
#1
K O Plaud-Ramos, M S Freeman, W Wei, E Guardincerri, J D Bacon, J Cowan, J M Durham, D Huang, J Gao, M A Hoffbauer, D J Morley, C L Morris, D C Poulson, Zhehui Wang
Consumer imaging sensors (CIS) are examined for real-time charged-particle detection and CR-39 plastic detector replacement. Removing cover glass from CIS is hard if not impossible, in particular for the latest inexpensive webcam models. We show that $10-class CIS are sensitive to MeV and higher energy protons and α-particles by using a (90)Sr β-source with its cover glass in place. Indirect, real-time, high-resolution detection is also feasible when combining CIS with a ZnS:Ag phosphor screen and optics...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27906470/retrospective-evaluation-of-whole-body-computed-tomography-for-tumor-staging-in-dogs-with-primary-appendicular-osteosarcoma
#2
Jessica L Talbott, Sarah E Boston, Rowan J Milner, Amandine Lejeune, Carlos H de M Souza, Kelvin Kow, Nicholas J Bacon, Jorge A Hernandez
OBJECTIVE: To evaluate whole body computed tomography (CT) for staging canine appendicular osteosarcoma. STUDY DESIGN: Retrospective case series. ANIMALS: Client-owned dogs diagnosed with appendicular osteosarcoma (n=39). METHODS: Medical records for client-owned dogs diagnosed with appendicular osteosarcoma from August 2008 to July 2014 were reviewed. Dogs were included if they had a confirmed diagnosis of appendicular osteosarcoma and were staged using whole body CT...
December 1, 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27899551/hispanic-americans-and-african-americans-with-multiple-sclerosis-have-more-severe-disease-course-than-caucasian-americans
#3
Rachel E Ventura, Ariel O Antezana, Tamar Bacon, Ilya Kister
Whether disease course in Hispanic Americans (HA) with multiple sclerosis (MS) is different from Caucasian Americans (CA) or African Americans (AA) is unknown. We compared MS severity in the three main ethnic populations in our tertiary MS clinics using disease duration-adjusted rank score of disability: Patient-Derived Multiple Sclerosis Severity Score (P-MSSS). The age- and gender-adjusted P-MSSS was significantly higher in HA (3.9 ± 2.6) and AA (4.5 ± 3.0) compared to CA (3.4 ± 2.6; p < 0...
November 29, 2016: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/27890054/results-of-the-2016-aorn-salary-and-compensation-survey
#4
Donald R Bacon, Kim A Stewart
AORN conducted its 14th annual compensation survey for perioperative nurses in June 2016. A multiple regression model was used to examine how several variables, including job title, education level, certification, experience, and geographic region, affect nurse compensation. Comparisons between the 2016 data and data from previous years are presented. The effects of other forms of compensation (eg, on-call compensation, overtime, bonuses, shift differentials, benefits) on base compensation rates also are examined...
December 2016: AORN Journal
https://www.readbyqxmd.com/read/27871338/mathematical-subtleties-and-scientific-knowledge-francis-bacon-and-mathematics-at-the-crossing-of-two-traditions
#5
Giuliano Mori
This article engages the much-debated role of mathematics in Bacon's philosophy and inductive method at large. The many references to mathematics in Bacon's works are considered in the context of the humanist reform of the curriculum studiorum and, in particular, through a comparison with the kinds of natural and intellectual subtlety as they are defined by many sixteenth-century authors, including Cardano, Scaliger and Montaigne. Additionally, this article gives a nuanced background to the 'subtlety' commonly thought to have been eschewed by Bacon and by Bacon's self-proclaimed followers in the Royal Society of London...
November 22, 2016: British Journal for the History of Science
https://www.readbyqxmd.com/read/27866872/commitment-issues-prep-adherence-in-injecting-drug-users
#6
Kimberly Page, Oliver Bacon
No abstract text is available yet for this article.
November 17, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27864481/meaningful-use-in-chronic-care-improved-diabetes-outcomes-using-a-primary-care-extension-center-model
#7
Samuel Cykert, Ann Lefebvre, Thomas Bacon, Warren Newton
BACKGROUND: The effect of practice facilitation that provides onsite quality improvement (QI) and electronic health record (EHR) coaching on chronic care outcomes is unclear. This study evaluates the effectiveness of such a program-similar to an agricultural extension center model-that provides these services. METHODS: Through the Health Information Technology for Economic and Clinical Health (HITECH) portion of the American Recovery and Reinvestment Act, the North Carolina Area Health Education Centers program became the Regional Extension Center for Health Information Technology (REC) for North Carolina...
November 2016: North Carolina Medical Journal
https://www.readbyqxmd.com/read/27861236/healthcare-access-and-prep-continuation-in-san-francisco-and-miami-following-the-u-s-prep-demo-project
#8
Susanne Doblecki-Lewis, Albert Liu, Daniel Feaster, Stephanie E Cohen, Gabriel Cardenas, Oliver Bacon, Erin Andrew, Michael A Kolber
Pre-exposure prophylaxis (PrEP) for prevention of HIV infection has demonstrated efficacy in randomized controlled trials as well as in demonstration projects. For PrEP implementation to result in significant reductions in HIV incidence for men who have sex with men (MSM) in the United States, sufficient access to PrEP care and continued engagement outside of demonstration projects is required. We report the results of a follow-up survey of 173 former participants from the Miami and San Francisco sites of the U...
November 14, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27857425/free-space-terahertz-radiation-from-a-lt-gaas-on-quartz-large-area-photoconductive-emitter
#9
David R Bacon, Andrew D Burnett, Matthew Swithenbank, Christopher Russell, Lianhe Li, Christopher D Wood, John Cunningham, Edmund H Linfield, A Giles Davies, Paul Dean, Joshua R Freeman
We report on large-area photoconductive terahertz (THz) emitters with a low-temperature-grown GaAs (LT-GaAs) active layer fabricated on quartz substrates using a lift-off transfer process. These devices are compared to the same LT-GaAs emitters when fabricated on the growth substrate. We find that the transferred devices show higher optical-to-THz conversion efficiencies and significantly larger breakdown fields, which we attribute to reduced parasitic current in the substrate. Through these improvements, we demonstrate a factor of ~8 increase in emitted THz field strength at the maximum operating voltage...
November 14, 2016: Optics Express
https://www.readbyqxmd.com/read/27807274/diverse-drug-resistant-subpopulations-of-mycobacterium-tuberculosis-are-sustained-in-continuous-culture
#10
Diepreye Ayabina, Charlotte Hendon-Dunn, Joanna Bacon, Caroline Colijn
Drug resistance to tuberculosis (TB) has become more widespread over the past decade. As such, understanding the emergence and fitness of antibiotic-resistant subpopulations is crucial for the development of new interventions. Here we use a simple mathematical model to explain the differences in the response to isoniazid (INH) of Mycobacterium tuberculosis cells cultured under two growth rates in a chemostat. We obtain posterior distributions of model parameters consistent with data using a Markov chain Monte Carlo (MCMC) method...
November 2016: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/27804265/hepatic-steatosis-is-common-in-adolescents-with-obesity-and-pcos-and-relates-to-de-novo-lipogenesis-but-not-insulin-resistance
#11
Melanie Cree-Green, Bryan C Bergman, Gregory V Coe, Lindsey Newnes, Amy D Baumgartner, Samantha Bacon, Ann Sherzinger, Laura Pyle, Kristen J Nadeau
OBJECTIVE: Increased liver fat and type 2 diabetes are prevalent in women with polycystic ovarian syndrome (PCOS) and cause excess mortality, yet little is known about their development during adolescence. The objective of this study was to measure hepatic steatosis and related metabolic contributors in girls with obesity, with and without PCOS. METHODS: Nondiabetic adolescents with obesity, 41 with PCOS (PCOS; age 15.0 [13.0-16.0] years, BMI 35.2 ± 0.61 kg/m(2) ) and 30 without PCOS (OB; age 14...
November 2016: Obesity
https://www.readbyqxmd.com/read/27802346/prevalence-recurrence-and-incidence-of-current-depressive-symptoms-among-people-living-with-hiv-in-ontario-canada-results-from-the-ontario-hiv-treatment-network-cohort-study
#12
Stephanie K Y Choi, Eleanor Boyle, John Cairney, Evan J Collins, Sandra Gardner, Jean Bacon, Sean B Rourke
INTRODUCTION: Current studies of depression among people living with HIV focus on describing its point prevalence. Given the fluctuating nature of depression and its profound impacts on clinical and quality-of-life outcomes, this study aimed to examine the prevalence, recurrence and incidence of current depressive symptoms and its underlying catalysts longitudinally and systematically among these individuals. METHODS: We conducted a prospective cohort study between October 1, 2007 and December 31, 2012 using longitudinal linked data sources...
2016: PloS One
https://www.readbyqxmd.com/read/27800021/efficacy-and-tolerability-of-dimethyl-fumarate-in-white-african-and-hispanic-americans-with-multiple-sclerosis
#13
Lana Zhovtis Ryerson, Rivka Green, Gladyne Confident, Krupa Pandey, Benjamin Richter, Tamar Bacon, Carrie Sammarco, Lisa Laing, Jennifer Kalina, Ilya Kister
BACKGROUND: Dimethyl fumarate (DMF) was approved by the US Food and Drug Administration (FDA) for treatment of relapsing-remitting multiple sclerosis (RRMS) based on two phase III randomized clinical trials (RCTs). There were not enough non-White patients enrolled in these RCTs to allow for subgroup analysis based on race. Efficacy and tolerability of DMF therapy across various racial groups is unknown. METHODS: Retrospective chart review was performed on all patients with RRMS who were started on DMF in two tertiary multiple sclerosis (MS) clinics...
November 2016: Therapeutic Advances in Neurological Disorders
https://www.readbyqxmd.com/read/27799909/neuromodulation-of-the-feedforward-dentate-gyrus-ca3-microcircuit
#14
REVIEW
Luke Y Prince, Travis J Bacon, Cezar M Tigaret, Jack R Mellor
The feedforward dentate gyrus-CA3 microcircuit in the hippocampus is thought to activate ensembles of CA3 pyramidal cells and interneurons to encode and retrieve episodic memories. The creation of these CA3 ensembles depends on neuromodulatory input and synaptic plasticity within this microcircuit. Here we review the mechanisms by which the neuromodulators aceylcholine, noradrenaline, dopamine, and serotonin reconfigure this microcircuit and thereby infer the net effect of these modulators on the processes of episodic memory encoding and retrieval...
2016: Frontiers in Synaptic Neuroscience
https://www.readbyqxmd.com/read/27779548/cervix-cancer-research-network-ccrn-improving-access-to-cervix-cancer-trials-on-a-global-scale
#15
David Gaffney, Bill Small, Henry Kitchener, Sang Young Ryu, Akila Viswanathan, Ted Trimble, Al Covens, Sarikapan Wilailak, Arb-Aroon Lertkhachonsuk, Chomporn Sitathanee, Umesh Mahantshetty, Brandon Fisher, Susan Springer, Thomas Pollatz, Antonius Spiller, Monica Bacon, Anuja Jhingran
Eighty-seven percent of cervix cancer occurs in less-developed regions of the world, and there is up to an 18-fold difference in mortality rate for cervix cancer depending on the region of the world. The Cervix Cancer Research Network (CCRN) was founded through the Gynecologic Cancer InterGroup with the aim of improving access to clinical trials in cervix cancer worldwide, and in so doing improving standards of care. The CCRN recently held its first international educational symposium in Bangkok. Sixty-two participants attended from 16 different countries including Pakistan, India, Bangladesh, Thailand, Malaysia, Singapore, Philippines, Taiwan, China, Vietnam, Korea, Japan, Columbia, Brazil, Canada, and the United States...
November 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27776760/types-of-control-in-acupuncture-clinical-trials-might-affect-the-conclusion-of-the-trials-a-review-of-acupuncture-on-pain-management
#16
Haiyong Chen, Zhipeng Ning, Wing Lok Lam, Wai-Yee Lam, Ying Ke Zhao, Jerry Wing Fai Yeung, Bacon Fung-Leung Ng, Eric Tat-Chi Ziea, Lixing Lao
Analgesic effects of acupuncture have been extensively studied in various clinical trials. However, the conclusion remains controversial, even among large scale randomized controlled trials. This study aimed to evaluate the association between the conclusion of the trials and the types of control used in those trials via systematic review. Published randomized controlled trials of acupuncture for pain were retrieved from electronic databases (Medline, AMED, Cochrane libraries, EMBASE, PsycINFO, Clinicaltrials...
October 2016: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/27774739/physician-agreement-regarding-the-expansion-of-pharmacist-professional-activities-in-the-management-of-patients-with-asthma
#17
Audrey Tilly-Gratton, Alexandrine Lamontagne, Lucie Blais, Simon L Bacon, Pierre Ernst, Roland Grad, Kim L Lavoie, Martha L McKinney, Eve Desplats, Francine M Ducharme
BACKGROUND: Asthma control remains suboptimal in Canada. Expansion of pharmacist's professional activities offers the opportunity to improve the interdisciplinary management of patients with asthma. OBJECTIVE: The aim of this study was to determine the level of agreement of physicians regarding the expansion of pharmacists' professional activities in the management of asthma patients. METHODS: We conducted a survey of randomly selected Quebec physicians in family medicine, paediatrics and emergency medicine...
October 24, 2016: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27756074/outcome-of-colorectal-cancer-patients-treated-with-combination-bevacizumab-therapy-a-pooled-retrospective-analysis-of-three-european-cohorts-from-the-angiopredict-initiative
#18
Johannes Betge, Ana Barat, Verena Murphy, Thomas Hielscher, Nicole C Van Grieken, Sebastian Belle, Tianzuo Zhan, Nicolai Härtel, Melanie Kripp, Orna Bacon, Martijn Cordes, Elaine W Kay, Henk M W Verheul, Maarten Neerincx, Bryan Hennessy, Ralf D Hofheinz, Timo Gaiser, Bauke Ylstra, Jochen H M Prehn, Diether Lambrechts, Annette T Byrne, Matthias P Ebert, Nadine Schulte
BACKGROUND/AIMS: This study is aimed at analyzing the survival rates and prognostic factors of stage IV colorectal cancer patients from 3 European cohorts undergoing combination chemotherapy with bevacizumab. METHODS: Progression free-survival (PFS) and overall survival (OS) were analyzed in 172 patients using the Kaplan-Meier method and uni- and multivariable Cox proportional hazards regression models. RESULTS: The median PFS was 9.7 and the median OS 27...
October 19, 2016: Digestion
https://www.readbyqxmd.com/read/27739464/nmr-based-serum-metabolomics-reveals-a-distinctive-signature-in-patients-with-lupus-nephritis
#19
Anupam Guleria, Avadhesh Pratap, Durgesh Dubey, Atul Rawat, Smriti Chaurasia, Edavalath Sukesh, Sanat Phatak, Sajal Ajmani, Umesh Kumar, Chunni Lal Khetrapal, Paul Bacon, Ramnath Misra, Dinesh Kumar
Management of patient with Lupus Nephritis (LN) continues to remain a challenge for the treating physicians because of considerable morbidity and even mortality. The search of biomarkers in serum and urine is a focus of researchers to unravel new targets for therapy. In the present study, the utility of NMR-based serum metabolomics has been evaluated for the first time in discriminating LN patients from non-nephritis lupus patients (SLE) and further to get new insights into the underlying disease processes for better clinical management...
October 14, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27730717/real-world-effectiveness-for-12-weeks-of-ledipasvir-sofosbuvir-for-genotype-1-hepatitis-c-the-trio-health-study
#20
E B Tapper, B R Bacon, M P Curry, D T Dieterich, S L Flamm, L E Guest, K V Kowdley, Y Lee, N C Tsai, Z M Younossi, N H Afdhal
Early data regarding the "real-world" experience with novel therapies for hepatitis C (HCV) are encouraging. Data are still limited, however, regarding real-world rates of sustained virologic response (SVR) for ledipasvir-sofosbuvir (LDV-SOF), particularly for patients with prior treatment failure. We performed a retrospective cohort study of 1597 patients with chronic genotype 1 HCV who were treated using 12 weeks of the following regimens LDV-SOF±ribavirin (RBV) (n=1521 without RBV, n=76 with RBV). The primary outcome was SVR-determined at 12 weeks in an intention-to-treat design...
October 11, 2016: Journal of Viral Hepatitis
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