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https://www.readbyqxmd.com/read/29345609/dietary-patterns-and-their-association-with-adiponectin-and-leptin-concentrations-throughout-pregnancy-a-prospective-cohort
#1
Nadya H Alves-Santos, Paula G Cocate, Ilana Eshriqui, Camila Benaim, Érica G Barros, Pauline M Emmett, Gilberto Kac
The aim of this study was to evaluate the association of dietary patterns (DP) with maternal adiposity indicators, leptin, adiponectin and insulin concentrations during pregnancy. A prospective cohort of pregnant women followed up at the 5th-13th, 20th -26th and 30th-36th gestational weeks and 30-40 d postpartum was conducted in Rio de Janeiro. A FFQ was administered in the third trimester (30th-36th gestational weeks). The reduced rank regression procedure was used to identify DP that explain response variables (dietary fibre and total fat) related to indicators of maternal adiposity (postpartum weight retention and gestational weight gain (GWG) adequacy), and plasma leptin, adiponectin and insulin concentrations...
January 18, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29344330/developments-in-rare-bone-diseases-and-mineral-disorders
#2
REVIEW
Siobhan Bacon, Rachel Crowley
In the last decade, there have been a number of significant advances made in the field of rare bone diseases. In this review, we discuss the expansion of the classification system for osteogenesis imperfecta (OI) and the resultant increase in therapeutic options available for management of OI. Bisphosphonates remain the most widely used intervention for OI, although the effect on fracture rate reduction is equivocal. We review the other therapies showing promising results, including denosumab, teriparatide, sclerostin, transforming growth factor β inhibition and gene targeted approaches...
January 2018: Therapeutic Advances in Chronic Disease
https://www.readbyqxmd.com/read/29339134/a-small-scale-process-for-predicting-donnan-and-volume-exclusion-effects-during-uf-df-process-development
#3
Jeff Abel, Andrew Kosky, Nicole Ball, Haley Bacon, Rahul Kaushik, Gerd R Kleemann
Achieving the desired final protein formulation using Ultrafiltration/Diafiltration (UF/DF) operations is an essential component of many protein purification processes. It is well documented that differences in the excipient and buffer concentrations exist between the diafiltration and retentate solutions when they have achieved equilibrium. Several publications have proposed ways to calculate these differences. However, the accuracy of these methods has been limited by the use of an estimated protein charge value...
January 12, 2018: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29322459/application-of-continuous-culture-for-assessing-antibiotic-activity-against-mycobacterium-tuberculosis
#4
Charlotte L Hendon-Dunn, Saba Anwar, Christopher Burton, Joanna Bacon
There is a proportion of the M. tuberculosis population that is refractory to the bactericidal action of antituberculosis antibiotics due to phenotypic tolerance. This tolerance can be impacted by environmental stimuli and the subsequent physiological state of the organism. It may be the result of preexisting populations of slow growing/non replicating bacteria that are protected from antibiotic action. It still remains unclear how the slow growth of M. tuberculosis contributes to antibiotic resistance and antibiotic tolerance...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29322458/a-flow-cytometry-method-for-assessing-m-tuberculosis-responses-to-antibiotics
#5
Charlotte L Hendon-Dunn, Stephen R Thomas, Stephen C Taylor, Joanna Bacon
Traditional drug susceptibility methods can take several days or weeks of incubation between drug exposure and confirmation of sensitivity or resistance. In addition, these methods do not capture information about viable organisms that are not immediately culturable after drug exposure. Here, we present a rapid fluorescence detection method for assessing the susceptibility of M. tuberculosis to antibiotics. Fluorescent markers Calcein violet-AM and SYTOX-green are used for measuring cell viability or cell death and to capture information about the susceptibility of the whole population and not just those bacteria that can grow in media postexposure...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29315683/the-emotional-resources-group-provisional-outcome-data-for-a-pilot-six-session-emotion-regulation-programme-for-secondary-care
#6
Thomas Bacon, Caitriona Doughty, Andrew Summers, Benjamin Wiffen, Zoe Stanley, Susan McAlpine
OBJECTIVE: To examine the effectiveness of a new, six-session emotion regulation group intervention designed for the secondary care setting: The Emotional Resources Group (ERG). METHOD: In this pilot study, participants were recruited by referral from secondary care mental health services. Forty-seven individuals participated in the study. Participants who attended the ERG were compared on measures of emotion regulation, well-being, and self-efficacy, pre- and post-intervention...
January 7, 2018: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29304190/enhancement-of-saltiness-perception-by-monosodium-glutamate-taste-and-soy-sauce-odor-a-near-infrared-spectroscopy-study
#7
Takuya Onuma, Hiroaki Maruyama, Nobuyuki Sakai
Previous studies have reported that the umami taste of monosodium L-glutamate (MSG) and salty-smelling odors (e.g., soy sauce, bacon, sardines) enhance the perception of saltiness. This study aimed to investigate the neural basis of the enhancement of saltiness in human participants using functional near-infrared spectroscopy (fNIRS). University students who had passed a taste panel test participated in this study. Sodium chloride solutions were presented with or without either 0.10% MSG or the odor of soy sauce...
January 3, 2018: Chemical Senses
https://www.readbyqxmd.com/read/29303301/reliable-channel-adapted-error-correction-bacon-shor-code-recovery-from-amplitude-damping
#8
Álvaro Piedrafita, Joseph M Renes
We construct two simple error correction schemes adapted to amplitude damping noise for Bacon-Shor codes and investigate their prospects for fault-tolerant implementation. Both consist solely of Clifford gates and require far fewer qubits, relative to the standard method, to achieve exact correction to a desired order in the damping rate. The first, employing one-bit teleportation and single-qubit measurements, needs only one-fourth as many physical qubits, while the second, using just stabilizer measurements and Pauli corrections, needs only half...
December 22, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29302875/sham-feeding-with-bacon-does-not-alter-transit-time-or-complete-examination-rate-during-small-bowel-capsule-endoscopy
#9
David Prichard, George Ou, Cherry Galorport, Robert Enns
BACKGROUND: During capsule endoscopy (CE) studies, the complete examination rate (CER) can be increased by prolonging capsule battery life or reducing gastric transit time (GTT) and/or small bowel transit time (SBTT). However, despite enhanced battery life, 10% of studies remain incomplete. Previously studied interventions to reduce SBTT and enhance CER have produced conflicting results. We hypothesize that this may be a consequence of an insufficiently potent stimulus of small bowel motility...
January 4, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29276716/lived-experiences-of-adolescent-athletes-following-sport-related-concussion
#10
Tamara C Valovich McLeod, Alyssa J Wagner, Cailee E Welch Bacon
Background: Previous studies have identified the effect of sport-related concussion on health-related quality of life through the use of patient-reported outcome measures. However, there has been little research exploring the underlying mechanisms that influence these perceptions of health-related quality of life among adolescent athletes who have sustained a sport-related concussion. Purpose: To explore the psychosocial aspects of concussion among adolescent athletes...
December 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29261687/engagement-of-vulnerable-youths-using-internet-platforms
#11
Melissa Chan, Tim M H Li, Yik Wa Law, Paul W C Wong, Michael Chau, Cecilia Cheng, King Wa Fu, John Bacon-Shone, Qijin Emily Cheng, Paul S F Yip
AIM: The aim of this study was to explore the online distress and help-seeking behavior of youths in Hong Kong. METHODS: A cross-sectional telephone-based survey was conducted among 1,010 young people in Hong Kong. Logistic regression analysis was then performed to identify the factors associated with those who reported expressing emotional distress online and the differences in help-seeking behavior among four groups of youths: (1) the non-distressed (reference) group; (2) "Did not seek help" group; (3) "Seek informal help" group; and (4) "Seek formal help" group...
2017: PloS One
https://www.readbyqxmd.com/read/29232472/harmonising-clinical-trials-within-the-gynecologic-cancer-intergroup-consensus-and-unmet-needs-from-the-fifth-ovarian-cancer-consensus-conference
#12
M A Bookman, A Okamoto, G Stuart, N Yanaihara, D Aoki, M Bacon, K Fujiwara, A González-Martín, P Harter, J W Kim, J Ledermann, E Pujade-Lauraine, M Quinn, K Ochiai
The Gynecologic Cancer InterGroup (GCIG) Fifth Ovarian Cancer Consensus Conference (OCCC) was held in Tokyo, Japan from 7 to 9 November 2015. It provided international consensus on 15 important questions in 4 topic areas, which were generated in accordance with the mission statement to establish 'International Consensus for Designing Better Clinical Trials'. The methodology for obtaining consensus was previously established and followed during the Fifth OCCC. All 29 clinical trial groups of GCIG participated in program development and deliberations...
November 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29178426/the-role-of-sentinel-lymph-node-mapping-in-small-animal-veterinary-medicine-a-comparison-with-current-approaches-in-human-medicine
#13
P Beer, A Pozzi, C Rohrer Bley, N Bacon, N S Pfammatter, C Venzin
The relevance of regional lymph node (LN) assessment to quantify the metastatic spread of cancer is well recognized in veterinary oncology. Evaluation of LNs is critical for tumour staging. However, sampling the correct LN may not be possible without sentinel lymph node (SLN) mapping. Methods for diagnostic imaging and intraoperative detection of SLNs are well established in human medicine, in particular, the combination of lymphoscintigraphy and intraoperative application of blue dyes. Nevertheless, alternative imaging techniques are available and have gained increasing interest...
November 27, 2017: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/29173373/results-of-the-2017-aorn-salary-and-compensation-survey
#14
Donald R Bacon, Kim A Stewart
AORN conducted its 15th annual compensation survey for perioperative nurses in June 2017. A multiple regression model was used to examine how several variables, including job title, educational level, certification, experience, and geographic region, affect nurse compensation. Comparisons between the 2017 data and data from previous years are presented. The effects of other forms of compensation (eg, on-call compensation, overtime, bonuses, shift differentials, benefits) on base compensation rates are examined...
December 2017: AORN Journal
https://www.readbyqxmd.com/read/29164756/survey-of-disability-related-content-in-australian-dietetics-programs
#15
Shannon Butler, Jane Kellett, Rachel Bacon, Annette Byron
AIM: Nutrition and dietetic services are an important component of healthcare for people living with a disability. The introduction of the National Disability Insurance Scheme (NDIS) in Australia is providing more opportunities for individuals to access these services from an Accredited Practising Dietitian (APD). The aim of this research was to identify how students in Australian tertiary dietetics programs are being prepared to provide these services to people with a disability. METHODS: A purpose-built questionnaire with eight open-ended questions was developed by the researchers to describe the disability-related content of university and professional placement learning opportunities and was distributed to all course conveners (or their nominated representative) of dietetics programs accredited by the Dietitians Association of Australia...
November 21, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29148874/managing-population-healthcare
#16
Muir Gray, Erica Pitini, Thomas Kelley, Neil Bacon
No abstract text is available yet for this article.
November 2017: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/29146316/comparative-evaluation-of-three-different-elisa-assays-and-hplc-esi-itms-ms-for-the-analysis-of-n-%C3%AE%C2%B5-carboxymethyl-lysine-in-food-samples
#17
Armando Gómez-Ojeda, Sarahi Jaramillo-Ortíz, Katarzyna Wrobel, Kazimierz Wrobel, Gloria Barbosa-Sabanero, Claudia Luevano-Contreras, Maria Pia de la Maza, Jaime Uribarri, Ma Dolores Del Castillo, Ma Eugenia Garay-Sevilla
N(ε)-carboxymethyl-lysine (CML) is measured in food, but there is a controversy concerning the most convenient yet reliable method(s) for this task. This work compares three different ELISA assays and HPLC-ESI-ITMS/MS for the analysis of CML in several food items. The four methods showed the same decreasing order of CML concentration: beef, bacon>chicken > fish>dairy products>grain products>fruits/vegetables. HPLC-ESI-ITMS/MS results highly correlated with those obtained by ELISA performed with monoclonal CML-antibody (β=0...
March 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29116955/patient-injury-assessment-and-treatment-characteristics-and-return-to-play-timelines-after-sport-related-concussion-an-investigation-from-the-athletic-training-practice-based-research-network
#18
Tamara C Valovich McLeod, Nicholas Kostishak, Barton E Anderson, Cailee E Welch Bacon, Kenneth C Lam
OBJECTIVE: To describe the patient, injury, assessment and treatment characteristics, as well as return-to-play timelines and clinical findings at discharge for adolescent patients after sport-related concussion. DESIGN: Retrospective analysis of electronic medical records. SETTING: Athletic training facilities of secondary school members of the Athletic Training Practice-Based Research Network (AT-PBRN). PATIENTS: In total, 1886 patient records were reviewed...
October 25, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29112956/hiv-1-persistence-following-extremely-early-initiation-of-antiretroviral-therapy-art-during-acute-hiv-1-infection-an-observational-study
#19
Timothy J Henrich, Hiroyu Hatano, Oliver Bacon, Louise E Hogan, Rachel Rutishauser, Alison Hill, Mary F Kearney, Elizabeth M Anderson, Susan P Buchbinder, Stephanie E Cohen, Mohamed Abdel-Mohsen, Christopher W Pohlmeyer, Remi Fromentin, Rebecca Hoh, Albert Y Liu, Joseph M McCune, Jonathan Spindler, Kelly Metcalf-Pate, Kristen S Hobbs, Cassandra Thanh, Erica A Gibson, Daniel R Kuritzkes, Robert F Siliciano, Richard W Price, Douglas D Richman, Nicolas Chomont, Janet D Siliciano, John W Mellors, Steven A Yukl, Joel N Blankson, Teri Liegler, Steven G Deeks
BACKGROUND: It is unknown if extremely early initiation of antiretroviral therapy (ART) may lead to long-term ART-free HIV remission or cure. As a result, we studied 2 individuals recruited from a pre-exposure prophylaxis (PrEP) program who started prophylactic ART an estimated 10 days (Participant A; 54-year-old male) and 12 days (Participant B; 31-year-old male) after infection with peak plasma HIV RNA of 220 copies/mL and 3,343 copies/mL, respectively. Extensive testing of blood and tissue for HIV persistence was performed, and PrEP Participant A underwent analytical treatment interruption (ATI) following 32 weeks of continuous ART...
November 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29110845/an-international-epidemiological-analysis-of-young-patients-with-non-small-cell-lung-cancer-adujov-clicap
#20
Luis Corrales-Rodríguez, Oscar Arrieta, Luis Mas, Renata Báez-Saldaña, Omar Castillo-Fernández, Normand Blais, Claudio Martín, Melissa Juárez, Priyanka Khanna, Allan Ramos-Esquivel, Ludwing Bacon, Leonardo Rojas, Beatriz Wills, George Oblitas, María Angelina Pérez, Mauricio Cuello, Andrés Felipe Cardona
BACKGROUND: A proportion of patients with NSCLC is diagnosed at 40 years or younger. These patients tend to be never-smokers, usually present with stage IV adenocarcinoma, and have somatic genomic alterations. Few studies have documented and analyzed epidemiological characteristics of this population. MATERIALS AND METHODS: We performed an international epidemiological analysis of 389 young patients with NSCLC. Data was collected from centers participating in the Latin American Consortium for Lung Cancer Research (AduJov-CLICaP)...
November 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
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