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https://www.readbyqxmd.com/read/28432981/hidden-markov-model-and-chapman-kolmogrov-for-protein-structures-prediction-from-images
#1
Md Sarwar Kamal, Linkon Chowdhury, Mohammad Ibrahim Khan, Amira S Ashour, João Manuel R S Tavares, Nilanjan Dey
Protein structure prediction and analysis are more significant for living organs to perfect asses the living organ functionalities. Several protein structure prediction methods use neural network (NN). However, the Hidden Markov model is more interpretable and effective for more biological data analysis compared to the NN. It employs statistical data analysis to enhance the prediction accuracy. The current work proposed a protein prediction approach from protein images based on Hidden Markov Model and Chapman Kolmogrov equation...
April 13, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28432681/retrospective-single-center-study-of-the-efficacy-of-large-spot-532%C3%A2-nm-laser-for-the-treatment-of-facial-capillary-malformations-in-44-patients-with-the-use-of-three-dimensional-image-analysis
#2
Bartłomiej Kwiek, Michał Rożalski, Cezary Kowalewski, Marcin Ambroziak
OBJECTIVE: We wanted to asses the efficacy of large spot 532 nm laser for the treatment of facial capillary malformations with the use of three-dimensional (3D) image analysis. STUDY DESIGN AND METHODS: Retrospective single center study on previously non-treated patients with facial capillary malformations (CM) was performed. A total of 44 consecutive Caucasian patients aged 5-66 were included. Patients had 3D photography performed before and after and had at least one single session of treatment with 532 nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser with contact cooling, fluencies ranging from 8 to 11...
April 22, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28427741/management-of-biliary-anastomotic-strictures-after-liver-transplantation
#3
REVIEW
Aydin Seref Koksal, Ahmet Tarik Eminler, Erkan Parlak, Ahmet Gurakar
Biliary strictures constitute 40% to 60% of the biliary complications after liver transplantation. They are more common after living donor related liver transplantation (LDLT) than orthotopic liver transplantation (OLT). Balloon dilation followed by multiple plastic stent insertion leads to a mean resolution rate of 84% in the treatment of ASs after OLT. Endoscopic treatment of ASs after LDLT is more difficult because of the small size of the ASs, their multiple number and peripheral location. Balloon dilation followed by multiple plastic stent insertion had a mean resolution rate of 53%...
March 30, 2017: Transplantation Reviews
https://www.readbyqxmd.com/read/28422966/taming-the-late-quaternary-phylogeography-of-the-eurasiatic-wild-ass-through-ancient-and-modern-dna
#4
E Andrew Bennett, Sophie Champlot, Joris Peters, Benjamin S Arbuckle, Silvia Guimaraes, Mélanie Pruvost, Shirli Bar-David, Simon J M Davis, Mathieu Gautier, Petra Kaczensky, Ralph Kuehn, Marjan Mashkour, Arturo Morales-Muñiz, Erich Pucher, Jean-François Tournepiche, Hans-Peter Uerpmann, Adrian Bălăşescu, Mietje Germonpré, Can Y Gündem, Mahmoud-Reza Hemami, Pierre-Elie Moullé, Aliye Ötzan, Margarete Uerpmann, Chris Walzer, Thierry Grange, Eva-Maria Geigl
Taxonomic over-splitting of extinct or endangered taxa, due to an incomplete knowledge of both skeletal morphological variability and the geographical ranges of past populations, continues to confuse the link between isolated extant populations and their ancestors. This is particularly problematic with the genus Equus. To more reliably determine the evolution and phylogeographic history of the endangered Asiatic wild ass, we studied the genetic diversity and inter-relationships of both extinct and extant populations over the last 100,000 years, including samples throughout its previous range from Western Europe to Southwest and East Asia...
2017: PloS One
https://www.readbyqxmd.com/read/28418335/evaluation-of-dynamic-disulphide-thiol-homeostasis-in-silica-exposed-workers
#5
Meşide Gündüzöz, Ceylan Bal, Murat Büyükşekerci, Salim Neşelioğlu, Türkan Nadir Öziş, Servet İritaş, Halil Kara, Özcan Erel
BACKGROUND: Oxidative stress is implicated as one of the main molecular mechanism underlying silicosis. AIMS: In this study, our aim was to asses the redox status in occupationally silica-exposed workers, by evaluating the dynamic thiol-disulphide homeostasis. STUDY DESIGN: Case-control study. METHODS: Thirty-six male workers occupationally exposed to silica particles and 30 healthy volunteers, working as office workers were included to the study...
April 5, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28412276/the-influence-of-hypertension-on-daytime-sleepiness-in-obstructive-sleep-apnea
#6
Helena Martynowicz, Robert Skomro, Paweł Gać, Grzegorz Mazur, Irena Porębska, Agnieszka Bryłka, Wojciech Nowak, Michał Zieliński, Anna Wojakowska, Rafał Poręba
Daytime sleepiness is a common symptom among hypertensive patients. The aim of this study was to determine subjective sleepiness assessed by Epworth Sleepiness Scale (ESS) and to asses sleep architecture in 304 patients with arterial hypertension. All patients underwent a standardized diagnostic overnight, polysomnography. The control group consisted of 67 normotensives. The hypertensive patients had a decreased sleep efficiency, mean and minimum oxygen saturation levels, and increased apnea/hypopnea index and oxygen desaturation index compared with normotensive patients...
March 27, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28397344/a-comparison-of-the-diagnostic-accuracy-of-magnetic-resonance-imaging-to-axillary-ultrasound-in-the-detection-of-axillary-nodal-metastases-in-newly-diagnosed-breast-cancer
#7
Matthew A Assing, Bhavika K Patel, Neel Karamsadkar, Jared Weinfurtner, Omar Usmani, John V Kiluk, Jennifer S Drukteinis
Patients with a diagnosis of invasive breast cancer are increasingly undergoing breast magnetic resonance imaging (MRI) for preoperative staging including evaluation of axillary lymph node metastases (ALNM). This retrospective study aims to evaluate the utility of adding axillary ultrasound (AUS) in the preoperative setting when an MRI is planned or has already been performed. This IRB approved, HIPAA compliant study reviewed a total of 271 patients with a new diagnosis of invasive breast cancer at a single institution, between June 1, 2010 and June 30, 2013...
April 10, 2017: Breast Journal
https://www.readbyqxmd.com/read/28393009/a-case-of-anti-aminoacyl-trna-synthetase-ars-antibody-positive-polymyositis-pm-dermatomyositis-dm-associated-interstitial-pneumonia-ip-successfully-controlled-with-bosentan-therapy
#8
Tomoyuki Naito, Yosuke Tanaka, Mitsunori Hino, Akihiko Gemma
A 72-year-old woman was admitted to our hospital and was diagnosed with interstitial pneumonia (IP) associated with amyopathic dermatomyositis (ADM). The patient experienced three acute IP exacerbations in the 7 years that followed, which were each treated and resolved with steroid pulse therapy. The patient was closely examined for respiratory failure with right heart catheterization (RHC), which demonstrated that she had a mean pulmonary artery pressure (mPAP) of 34 mmHg. The patient was thus diagnosed as having pulmonary hypertension (PH) associated with anti-synthetase syndrome (ASS) and was started on bosentan therapy, which led to improvements in mPAP as well as in subjective symptoms over time...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28371186/quantum-mechanics-approach-to-hydration-energies-and-structures-in-alanine-and-dialanine
#9
Giuseppe Lanza, Maria Assunta Chiacchio
A systematic approach to the phenomena related to hydration of biomolecules is reported at the state of art of electronic structure methods. Large scale CCSD(T), MP4-SDQ, MP2 and DFT(M06-2X) calculations for some hydrated complexes of alanine and dialanine (Ala.13H2O, Ala2H+.18H2O and Ala2.18H2O) are compared with experimental data and other elaborate modeling to asses the reliability of a simple bottom-up approach. The inclusion of a minimal number of water molecules for microhydration of the polar groups together with the polarizable continuum model are sufficient to reproduce the relative bulk thermodynamic functions of the considered biomolecules...
April 2, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28364306/-antipyretics-in-intensive-care-patients
#10
A Simon, A Leffler
BACKGROUND: Antipyretics are among the most widely prescribed drugs in German hospitals. Despite this widespread use, their role for treatment of critically ill patients still remains unclear. In particular, the questionable positive effects of reducing fever are discussed. OBJECTIVES: In this review we aimed to summarize and discuss current study results covering the use of antipyretics in critically ill patients. Suspected effects with regard to fever reduction and lethality should be considered...
March 31, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28348720/the-optimum-study-emdr-therapy-in-pregnant-women-with-posttraumatic-stress-disorder-after-previous-childbirth-and-pregnant-women-with-fear-of-childbirth-design-of-a-multicentre-randomized-controlled-trial
#11
M A M Baas, C A I Stramrood, L M Dijksman, A de Jongh, M G van Pampus
Background: Approximately 3% of women develop posttraumatic stress disorder (PTSD) after giving birth, and 7.5% of pregnant women show a pathological fear of childbirth (FoC). FoC or childbirth-related PTSD during (a subsequent) pregnancy can lead to a request for an elective caesarean section as well as adverse obstetrical and neonatal outcomes. For PTSD in general, and several subtypes of specific phobia, eye movement desensitization and reprocessing (EMDR) therapy has been proven effective, but little is known about the effects of applying EMDR during pregnancy...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/28347133/antimony-and-arsenic-behavior-during-fe-ii-induced-transformation-of-jarosite
#12
Niloofar Karimian, Scott G Johnston, Edward D Burton
Jarosite can be an important scavenger for arsenic (As) and antimony (Sb) in acid mine drainage (AMD) and acid sulfate soil (ASS) environments. When subjected to reducing conditions, jarosite may undergo reductive dissolution, thereby releasing As, Sb, and Fe(2+) coincident with a rise in pH. These conditions can also trigger the Fe(2+)-induced transformation of jarosite to more stable Fe(III) minerals, such as goethite. However, the consequences of this transformation process for As and Sb are yet to be methodically examined...
April 5, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28346510/study-on-the-biodegradation-of-crude-oil-by-free-and-immobilized-bacterial-consortium-in-marine-environment
#13
Qingguo Chen, Jingjing Li, Mei Liu, Huiling Sun, Mutai Bao
Five strains of bacteria, namely, Exiguobacterium sp. ASW-1, Pseudomonas aeruginosa strain ASW-2, Alcaligenes sp. ASW-3, Alcaligenes sp. ASS-1, and Bacillus sp. ASS-2, were isolated from the Zhejiang coast in China. The mixed flora of the five strains performed well with degrading 75.1% crude oil (1%, w/v) in 7 days. The calcium alginate-activated carbon embedding carrier was used to immobilize bacterial consortium. Immobilized cells performed better than free ones in variations of environmental factors containing incubated temperature, initial pH, salinity of the medium and crude oil concentration...
2017: PloS One
https://www.readbyqxmd.com/read/28343232/genetic-polymorphisms-in-defb1-and-mirna202-are-involved-in-salivary-human-%C3%AE-defensin-1-levels-and-caries-experience-in-children
#14
Andrea Lips, Leonardo Santos Antunes, Lívia Azeredo Antunes, Júlia Guimarães Barcellos de Abreu, Driely Barreiros, Daniela Silva Barroso de Oliveira, Ana Carolina Batista, Paulo Nelson-Filho, Léa Assed Bezerra da Silva, Raquel Assed Bezerra da Silva, Gutemberg Gomes Alves, Erika Calvano Küchler
The antimicrobial peptides human β-defensins (hBDs) are encoded by β-defensin genes (DEFBs) and are possibly involved in caries susceptibility. In this study we aimed (1) to investigate the relationship between salivary hBDs and caries and (2) to evaluate the association of genetic polymorphisms in DEFB1 and microRNA202 (miRNA202) with salivary levels of hBDs and caries experience. Two data sets were available for this study, totalizing 678 Brazilian children. Dental examination and saliva collection were performed in all included children...
March 25, 2017: Caries Research
https://www.readbyqxmd.com/read/28340202/validity-and-reproducibility-of-the-start-back-tool-dutch-version-in-patients-with-low-back-pain-in-primary-care-settings
#15
Jasper D Bier, Raymond W J G Ostelo, Miranda L van Hooff, Bart W Koes, Arianne P Verhagen
Objective: To translate, and to investigate the reliability and validity of the STarT Back screening tool (SBT) in the primary care setting among patients with non-specific low back pain (LBP). Methods: The SBT was formally translated in Dutch following a multistep approach for forward and backward translation. General practitioners and physiotherapists included patients with LBP. Patients completed a baseline a questionnaire and a follow-up at three days and three months...
March 9, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28333830/minimal-variation-in-anti-a-and-b-titers-among-healthy-volunteers-over-time-implications-for-the-use-of-out-of-group-blood-components
#16
Ulrik Sprogøe, Mark Yazer, Mads Hvidkjær Rasmussen, Berit Antonsen, Claus Bistrup, Kristian Assing
BACKGROUND: Using potentially out-of-group blood components, like low titer A plasma and O whole blood, in the resuscitation of trauma patients is becoming increasingly popular. However, very little is known whether the donors' anti-A and/or -B titers change over time and whether repeated titer measurements on the same donor are required to ensure that each donation produces a low titer product. METHODS: The anti-A and/or -B titers were measured on 56 healthy adult volunteers (47 blood donors; 9 blood center personnel) every three months for 12 consecutive months using an automated solid phase analyzer...
March 22, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28327267/a-modified-nance-palatal-arch-for-the-treatment-of-ectopically-erupting-permanent-first-molars
#17
Fábio Lourenço Romano, Juliana Arid, Alexandra Mussolino de Queiroz, Raquel Assed Bezerra Segato, Paulo Nelson Filho
Permanent teeth that remain impacted could lead to the early loss of primary teeth and cause space problems in dental arches. We present two cases of ectopic eruption of the permanent maxillary first molars treated with soft distal movements using a modified Nance palatal arch (NPAm). The wire was soldered to the band and positioned distally to serve as support for the elastic chain, which was attached to a bonded button on the occlusal surface. After a few months, the ectopic eruption was corrected, preserving the adjacent primary teeth and restoring the occlusion...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327265/association-between-body-mass-index-and-caries-experience-in-brazilian-children-and-adolescents
#18
Raquel Assed Bezerra da Silva, Driely Barreiros, Sara Oliveira, Lea Assed Bezerra da Silva, Paulo Nelson-Filho, Erika Calvano Küchler
PURPOSE: The purpose of this study was to evaluate the association between caries and body mass index (BMI) deviations in Brazilian schoolchildren and adolescents. METHODS: A total of 237 three- to 15-year-old children, all undergoing treatment in a university pediatric dental clinic, was evaluated. Caretakers answered a questionnaire on sociodemographic, ethnicity, oral hygiene, and dietary information. The children's height was measured in centimeters, the weight in kilograms, and BMIs were calculated...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28320415/the-development-of-integrated-diabetes-care-in-the-netherlands-a-multiplayer-self-assessment-analysis
#19
Nick Zonneveld, Lidewij E Vat, Hans Vlek, Mirella M N Minkman
BACKGROUND: Since recent years Dutch diabetes care has increasingly focused on improving the quality of care by introducing the concept of care groups (in Dutch: 'zorggroepen'), care pathways and improving cooperation with involved care professionals and patients. This study examined how participating actors in care groups assess the development of their diabetes services and the differences and similarities between different stakeholder groups. METHODS: A self-evaluation study was performed within 36 diabetes care groups in the Netherlands...
March 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28319567/treatment-of-biliary-stricture-after-live-donor-liver-transplantation-with-combined-metal-and-plastic-stent-%C3%A4-nsertion-a-feasibility-and-safety-study
#20
Erkan Parlak, Aydin Seref Koksal, Ahmet Tarik Eminler, Bilal Toka, Mustafa Ihsan Uslan
BACKGROUND: Fully covered-self expandable metal stents (Fc-SEMSs) have a challenging use in the treatment of anastomosis strictures (ASs) after live donor liver transplantation (LDLT) because they can occlude secondary branch biliary ducts when placed above the biliary bifurcation. In this study we evaluated the technical feasibility and safety of combining Fc-SEMSs with plastic stent(s) inserted to the secondary branch biliary ducts for the treatment of ASs after LDLT. METHODS: The study group included 22 patients (12 men, aged 51±11 years) with anastomotic biliary stricture after LDLT...
March 18, 2017: Transplantation
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