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https://www.readbyqxmd.com/read/28735815/intensive-lifestyle-intervention-is-particularly-advantageous-in-poorly-controlled-type-2-diabetes
#1
E Sbroma Tomaro, R Pippi, E Reginato, C Aiello, L Buratta, C Mazzeschi, C Perrone, C Ranucci, A Tirimagni, A Russo, C Fatone, C Fanelli, P De Feo
BACKGROUND AND AIMS: It is unknown whether lifestyle change is effective in people with type 2 diabetes with inadequate glucose control. The aim of this study was to asses, in a group of people with type 2 diabetes, the impact of baseline values of glycosylated haemoglobin (HbA1c) on the effects of an intensive lifestyle intervention on metabolic, clinical and strength parameters. METHODS AND RESULTS: 222 people with type 2 diabetes with mean ± standard deviation baseline HBA1c of 7...
June 21, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28733524/arginine-auxotrophic-gene-signature-in-paediatric-sarcomas-and-brain-tumours-provides-a-viable-target-for-arginine-depletion-therapies
#2
Ashley Vardon, Madhumita Dandapani, Daryl Cheng, Paul Cheng, Carmela De Santo, Francis Mussai
Paediatric sarcomas and brain tumours, remain cancers of significant unmet need, with a poor prognosis for patients with high risk disease or those who relapse, and significant morbidities from treatment for those that survive using standard treatment approaches. Novel treatment strategies, based on the underlying tumour biology, are needed to improve outcomes. Arginine is a semi-essential amino acid that is imported from the extracellular microenvironment or recycled from intracellular precursors through the combined expression of the enzymes ornithine transcarbamylase (OTC), argininosuccinate synthase (ASS) and argininosuccinate lyase (ASL) enzymes...
June 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28724827/angioid-streaks-in-a-case-of-camurati-engelmann-disease
#3
Bet L Tugcu, Taha Sezer, Ahmet Elbay, Hakan Özdemir
Camurati-Engelmann disease (CED) is a rare autosomal dominant disease with various phenotypic expressions. The hallmark of the disease is bilateral symmetric diaphyseal hyperostosis of the long bones with progressive involvement of the metaphysis. Ocular manifestations occur rarely and mainly result from bony overgrowth of the orbit and optic canal stenosis. We report a case of CED showing angioid streaks (ASs) in both fundi with no macular involvement and discuss the possible theories of the pathogenesis of AS in this disease...
July 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28723966/activated-carbon-a-useful-medium-to-bind-chlordecone-in-soil-and-limit-its-transfer-to-growing-goat-kids
#4
Sarah Yehya, Matthieu Delannoy, Agnès Fournier, Moomen Baroudi, Guido Rychen, Cyril Feidt
Chlordecone (Kepone) (CLD) is a highly persistent pesticide which was extensively used in the French West Indies; high levels of CLD can still currently be found in large agricultural areas. As CLD transfers from soil to animals mainly via involuntary ingestion, the consumption of foodstuffs derived from animals raised in contaminated areas may significantly contribute to exposure of humans to CLD. The present study was designed to test the efficacy of two different activated carbons (ACs) sources in limiting CLD transfer from soil to animal...
2017: PloS One
https://www.readbyqxmd.com/read/28717255/sequential-stable-isotope-analysis-reveals-differences-in-multi-year-dietary-history-of-three-sympatric-equid-species-in-sw-mongolia
#5
Martina Burnik Šturm, Oyunsaikhan Ganbaatar, Christian C Voigt, Petra Kaczensky
1. Competition among sympatric wild herbivores is reduced by different physiological, morphological, and behavioral traits resulting in different dietary niches. Wild equids are a rather uniform group of large herbivores which have dramatically declined in numbers and range. Correlative evidence suggests that pasture competition with livestock is one of the key factors for this decline, and the situation may be aggravated in areas where different equid species overlap. 2. The Dzungarian Gobi is currently the only place where two wild equid species coexist and share the range with the domesticated form of a third equid species...
August 2017: Journal of Applied Ecology
https://www.readbyqxmd.com/read/28715659/fetal-heart-rate-variation-after-corticosteroids-for-fetal-maturation
#6
Olga Knaven, Wessel Ganzevoort, Marjon de Boer, Hans Wolf
INTRODUCTION: Several studies report a decrease of fetal heart rate (FHR) short-term variation (STV) after corticosteroids for improvement of fetal maturity and advice not to deliver a fetus for low STV within 2-3days after corticosteroids. However, literature is not unanimous in this respect. This study intends to asses STV longitudinally after corticosteroid administration. MATERIAL AND METHODS: A retrospective cohort study in a tertiary perinatal centre from 2009 to 2015 included all women who had been treated with corticosteroids at gestational age of 26-34 weeks, had a computerized cardiotocography (cCTG) before and after medication and did not deliver within 48h...
June 29, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28714771/acute-effect-of-static-stretching-on-lower-limb-movement-performance-by-using-stabl-virtual-reality-system
#7
Mariam A Ameer, Qassim I Muaidi
CONTEXT: The effect of acute static stretch (ASS) on the lower limb RT has been recently questioned to decrease the risk of falling and injuries in situations requiring a rapid reaction, as in the cases of balance disturbance. OBJECTIVE: The main purpose of this study was to detect the effect of ASS on the lower limb RT by using virtual reality device. DESIGN: Two Group Control Group design. SETTING: Research laboratory...
July 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28699020/manipulation-under-anaesthetic-for-frozen-shoulder-using-codman-s-paradox-a-safe-and-early-return-of-function
#8
Oren Tsvieli, Ehud Atoun, Paolo Consigliere, Ioannis Polyzois, Joanna Walecka, Rajib Pradhan, Giorgio Ippolito, Ehud Rath, Ofer Levy
PURPOSE: Although previously frozen shoulder was thought to resolve by two to three years, recent studies demonstrated the symptoms can remain for much longer. Manipulation under anaesthetic (MUA) has been shown to be successful in relieving pain and restoring function. Yet, concerns have been raised regarding its safety and the risks of complications. We utilise Codman's paradox to manipulate the shoulder, avoiding rotational torque on the humerus. The aim of our study was to asses shoulder function in the early post MUA period...
July 11, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28698536/metformin-use-associated-with-lower-risk-of-cancer-in-patients-with-diabetes-mellitus-type-2
#9
Jasna Kusturica, Aida Kulo Ćesić, Edis Gušić, Sanita Maleškić, Maida Rakanović-Todić, Damir Šečić
Aim In order to increase the database related to the antineoplastic potential of metformin, association between the use of metformin and risk of cancer occurence in patients with diabetes mellitus type 2 (DM2) was investigated. Methods In this cross-sectional study, medical records of patients with DM2 were reviewed for cancer occurence. Data on age, body mass index (BMI), alcohol and nicotine consumption, glucose and HbA1c levels, duration of DM2, medication used in the treatment of DM2 and cancer occurence were collected and analyzed...
August 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28692927/coal-emissions-adverse-human-health-effects-associated-with-ultrafine-nano-particles-role-and-resultant-engineering-controls
#10
Marcos L S Oliveira, Orlando G Navarro, Tito J Crissien, Bernardo F Tutikian, Kátia da Boit, Elba C Teixeira, Juan J Cabello, Dayana M Agudelo-Castañeda, Luis F O Silva
There are multiple elements which enable coal geochemistry: (1) boiler and pollution control system design parameters, (2) temperature of flue gas at collection point, (3) feed coal and also other fuels like petroleum coke, tires and biomass geochemistry and (4) fuel feed particle size distribution homogeneity distribution, maintenance of pulverisers, etc. Even though there is a large number of hazardous element pollutants in the coal-processing industry, investigations on micrometer and nanometer-sized particles including their aqueous colloids formation reactions and their behaviour entering the environment are relatively few in numbers...
July 7, 2017: Environmental Research
https://www.readbyqxmd.com/read/28691452/bilateral-symmetry-of-anterior-maxillary-incisors-evaluation-of-a-community-based-population
#11
Z Ormianer, A L Solodukhin, D Lauritano, P Segal, D Lavi, F Carinci, J Block
The final outcome of dental treatment needs to be not only clinically sufficient, but also esthetically pleasing. Bilateral symmetry in the maxillary incisor teeth is of significant importance in esthetic dentistry. In restorative dentistry, symmetry refers to the appearance of balance around the dental midline. The purpose of this study was to measure and compare the maxillary incisor teeth dimensions from both sides of the dental midline, in order to asses if this symmetry occurs naturally. From the student community population at Tel Aviv University, 66 students between the ages of 20-35 (35 males, 31 females) were enrolled and gave consent...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28688654/thyroid-cancer-is-more-likely-to-be-detected-incidentally-on-imaging-in-private-hospital-patients
#12
Jonathan Zagzag, Alexander Kenigsberg, Kepal N Patel, Keith S Heller, Jennifer B Ogilvie
BACKGROUND: The incidence of well-differentiated thyroid cancer (WDTC) is increasing. Patients with higher socioeconomic status have higher rates of WDTC, possibly due to increased imaging and overdiagnosis. We compared methods of WDTC diagnosis in patients treated at a public and an adjacent private university hospital. MATERIALS AND METHODS: Patients with WDTC at the two hospitals between 2004 and 2010 were included. Patients were categorized into having their WDTC discovered on physical examination or on unrelated imaging...
July 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28686464/the-influence-of-liquids-on-the-mechanical-properties-of-allografts-in-bone-impaction-grafting
#13
David Putzer, Christoph Gert Ammann, Débora Coraça-Huber, Ricarda Lechner, Werner Schmölz, Michael Nogler
Allografts are used to compensate for bone defects resulting from revision surgery, tumor surgery, and reconstructive bone surgery. Although it is well known that the reduction of fat content of allografts increases mechanical properties, the content of liquids with a known grain size distribution has not been assessed so far. The aim of the study was to compare the mechanical properties of dried allografts (DA) with allografts mixed with a saline solution (ASS) and with allografts mixed with blood (AB) having a similar grain size distribution...
July 7, 2017: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/28686442/accuracy-of-frequencies-obtained-with-the-aid-of-explicitly-correlated-wave-function-based-methods
#14
Gunnar Schmitz, Ove Christiansen
We asses the basis set convergence of harmonic frequencies using different explicitly correlated wave function based methods. All commonly available CCSD(T) variants as well as MP2-F12 and MP4(F12*) are considered and a hierarchy of the different approaches is established. As for reaction and atomization energies CCSD(F12*)(T*) is a close approximation to CCSD(F12)(T*) and clearly superior to the other tested approximations. The used scaling for the triples correction enhances the accuracy relative to CCSD(F12*)(T) especially for small basis sets and is very attractive since no additional computational costs are added...
July 7, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28679936/knowledge-attitude-and-practice-tools-for-health-education-among-diabetic-patients
#15
Samantha Ismaile, Fuad Alhosban, Alyah Almoajel, Ahmed Albarrak, Mowafa Househ
Health education is an integral part of self-management programs and an important element for the control and effective management of any chronic disease including diabetes. Patient Knowledge, Awareness, and Practices (KAP) are considered to be the most important factors for assessing the results of health education in patients with diabetes. In order to develop such health education models, it is important to have a validated and reliable tools which asses a diabetic patient's knowledge, attitude and practice...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28677884/assessing-the-proposed-association-between-ded-and-gluten-free-diet-introduction-in-celiac-children
#16
Alexandra Mussolino de Queiroz, Juliana Arid, Fabrício Kitazono de Carvalho, Raquel Assed Bezerra da Silva, Erika Calvano Küchler, Regina Sawamura, Lea Assed Bezerra da Silva, Paulo Nelson-Filho
A strong association between celiac disease (CD) and dental enamel defects (DEDs) have been extensively reported, however, the nature of this relationship is still unclear. The aim of this study was to evaluate DEDs phenotype in CD individuals according to the time they were introduced to a gluten-free diet (GFD). Forty-five CD individuals were examined by a pediatric dentist. DEDs were classified according to the type of affected teeth. CD individuals were classified into two groups (with or without DEDs) and the differences between these groups were tested using chi-square or Fisher´s exact tests and t-test to compare differences between means...
July 2017: Special Care in Dentistry
https://www.readbyqxmd.com/read/28675883/mass-loading-of-typical-artificial-sweeteners-in-a-pig-farm-and-their-dissipation-and-uptake-by-plants-in-neighboring-farmland
#17
Ling Ma, Yarui Liu, Jiayao Xu, Hongwen Sun, Hao Chen, Yiming Yao, Peng Zhang, Fengju Shen, Aldredo C Alder
Pig farm is an important potential source for artificial sweeteners (ASs) in the environment due to their wide use as additives in pig feed. The objective of this study was to evaluate the fate of typical ASs in pig farm and neighboring farmland. For this purpose, the levels of four typical artificial ASs, i.e. saccharin (SAC), cyclamate (CYC), acesulfame (ACE) and sucralose (SUC), in pig feed and manure from a pig farm and water samples from an on-farm wastewater treatment plant (WWTP) in Tianjin, China were measured and the mass loadings and removal efficiencies were assessed...
July 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28674219/low-genetic-diversity-of-the-endangered-indian-wild-ass-equus-hemionus-khur-as-revealed-by-microsatellite-analyses
#18
Devendra Khaire, Ashwin Atkulwar, Sameera Farah, Mumtaz Baig
No abstract text is available yet for this article.
June 27, 2017: Journal of Genetics
https://www.readbyqxmd.com/read/28666535/effects-of-a-preschool-intervention-on-physical-activity-and-body-composition
#19
Kristi Bree Adamo, Niko Sebastian Wasenius, Kimberly Paige Grattan, Alysha Leila Jean Harvey, Patti-Jean Naylor, Nicolas James Barrowman, Gary Scott Goldfield
OBJECTIVE: To investigate the effect of a preschool physical activity intervention program delivered in licensed childcare settings, with or without a parent-facilitated home component, on children's daily physical activity, sedentary time, and body composition. STUDY DESIGN: For this cluster randomized controlled trial, 18 childcare centers were randomly allocated in equal numbers to the typical curriculum comparison group, childcare intervention alone (CC), or childcare intervention with parental involvement...
June 27, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28658303/critical-role-of-sik3-in-mediating-high-salt-and-il-17-synergy-leading-to-breast-cancer-cell-proliferation
#20
Suneetha Amara, Ciera Majors, Bipradas Roy, Salisha Hill, Kristie L Rose, Elbert L Myles, Venkataswarup Tiriveedhi
Chronic inflammation is a well-known precursor for cancer development and proliferation. We have recently demonstrated that high salt (NaCl) synergizes with sub-effective interleukin (IL)-17 to induce breast cancer cell proliferation. However, the exact molecular mechanisms mediating this effect are unclear. In our current study, we adopted a phosphoproteomic-based approach to identify salt modulated kinase-proteome specific molecular targets. The phosphoprotemics based binary comparison between heavy labelled MCF-7 cells treated with high salt (Δ0...
2017: PloS One
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