keyword
https://read.qxmd.com/read/38282759/impact-of-a-mobile-health-intervention-based-on-multi-theory-model-of-health-behavior-change-on-self-management-in-patients-with-differentiated-thyroid-cancer-protocol-for-a-randomized-controlled-trial
#21
JOURNAL ARTICLE
Yang Jiang, Xiangju Sun, Maomin Jiang, Hewei Min, Jing Wang, Xinghua Fu, Jiale Qi, Zhenjie Yu, Xiaomei Zhu, Yibo Wu
INTRODUCTION: Theoretical models of health behavior are important guides for disease prevention and detection, treatment and rehabilitation, and promotion and maintenance of physical and mental health, but there are no intervention studies related to differentiated thyroid cancer (DTC) that use theoretical models of health as a guide. In this study, we used a microblogging platform as an intervention vehicle and mobile patient-doctor interactive health education as a means of intervention, with the aim of improving the health behaviors of DTC patients as well as the corresponding clinical outcomes...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38281222/glis3-expression-in-the-thyroid-gland-in-relation-to-tsh-signaling-and-regulation-of-gene-expression
#22
JOURNAL ARTICLE
Hong Soon Kang, Sara A Grimm, Xiao-Hui Liao, Anton M Jetten
Loss of GLI-Similar 3 (GLIS3) function in mice and humans causes congenital hypothyroidism (CH). In this study, we demonstrate that GLIS3 protein is first detectable at E15.5 of murine thyroid development, a time at which GLIS3 target genes, such as Slc5a5 (Nis), become expressed. This, together with observations showing that ubiquitous Glis3KO mice do not display major changes in prenatal thyroid gland morphology, indicated that CH in Glis3KO mice is due to dyshormonogenesis rather than thyroid dysgenesis...
January 28, 2024: Cellular and Molecular Life Sciences: CMLS
https://read.qxmd.com/read/38278171/hyperthyroidism
#23
REVIEW
Layal Chaker, David S Cooper, John P Walsh, Robin P Peeters
Thyrotoxicosis causes a variety of symptoms and adverse health outcomes. Hyperthyroidism refers to increased thyroid hormone synthesis and secretion, most commonly from Graves' disease or toxic nodular goitre, whereas thyroiditis (typically autoimmune, viral, or drug induced) causes thyrotoxicosis without hyperthyroidism. The diagnosis is based on suppressed serum concentrations of thyroid-stimulating hormone (TSH), accompanied by free thyroxine and total or free tri-iodothyronine concentrations, which are raised (overt hyperthyroidism) or within range (subclinical hyperthyroidism)...
January 23, 2024: Lancet
https://read.qxmd.com/read/38277114/factors-predicting-remission-in-hyperthyroid-patients-after-low-dose-i-131-therapy-20%C3%A2-years-retrospective-study-from-a-tertiary-care-hospital
#24
JOURNAL ARTICLE
Shrinivas Yuvan S, Subramanyam Padma, Palaniswamy Shanmuga Sundaram
OBJECTIVE: To assess the therapeutic outcome and factors predicting remission in hyperthyroid patients treated with low-dose I-131 (radioactive iodine) from a tertiary care hospital in South India. METHODS: This 20-year single-institutional retrospective study was carried out on 3891 hyperthyroid adult patients. Only those patients with complete clinical records were audited. Selection criteria were based on patients with scintigraphic diagnosis of either Graves' disease (GD), toxic multinodular goitre (TMNG) or autonomous toxic nodule (ATN) and the records of those who received low-dose I-131 therapy (LDT) between March 2000 and 2020 at Amrita Institute, Cochin were analysed...
January 26, 2024: Annals of Nuclear Medicine
https://read.qxmd.com/read/38271814/the-hypothalamic-pituitary-thyroid-axis-is-intact-in-male-insulin-receptor-substrate-4-knockout-mice
#25
JOURNAL ARTICLE
Emilie Brûlé, Xiang Zhou, Ying Wang, Evan R S Buddle, Luisina Ongaro, Mary Loka, Anita Boelen, Daniel Bernard
OBJECTIVE: Loss of function mutations in the insulin receptor substrate 4 (IRS4) gene cause a rare form of X-linked congenital central hypothyroidism in boys and men. Affected individuals show decreased thyroid-stimulation hormone (TSH) secretion. Members of the IRS family canonically act as scaffold proteins between tyrosine kinase receptors and downstream effectors. How loss of IRS4 affects TSH synthesis or secretion is unresolved. We therefore assessed IRS4's role in the hypothalamic-pituitary-thyroid axis of Irs4 knockout mice...
January 1, 2024: European Thyroid Journal
https://read.qxmd.com/read/38271262/comparison-of-recombinant-human-thyroid-stimulating-hormone-and-thyroid-hormone-withdrawal-for-131-i-therapy-in-patients-with-intermediate-to-high-risk-thyroid-cancer-a-systematic-review-and-meta-analysis
#26
JOURNAL ARTICLE
Sohyun Park, Ji-In Bang, Keunyoung Kim, Youngduk Seo, Ari Chong, Chae Moon Hong, Dong-Eun Lee, Miyoung Choi, Sang-Woo Lee, So Won Oh
BACKGROUND: This meta-analysis and systematic review aimed to evaluate the therapeutic efficacy and advantages associated with the use of recombinant human thyroid-stimulating hormone (rhTSH) for radioactive iodine (RAI) therapy in patients with intermediate- to high-risk differentiated thyroid cancer. PATIENTS AND METHODS: MEDLINE, EMBASE, and Cochrane databases were searched to identify relevant articles reporting clinical outcomes of rhTSH compared with thyroid hormone withdrawal (THW) in patients with intermediate- to high-risk differentiated thyroid cancer published between January 2012 and June 2023...
March 1, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38269223/evaluating-the-effectiveness-of-triiodothyronine-suppression-and-withdrawal-versus-thyrogen-injections-in-thyroid-cancer-assessments
#27
JOURNAL ARTICLE
Nada M Abdulhameed, Mazin A Janabi
Objective This study aimed to evaluate the specificity and effectiveness of triiodothyronine (T3) suppression and withdrawal, as compared to the conventional diagnostic approach using Thyrogen recombinant thyroid-stimulating hormone (TSH) injections, in the assessment of thyroid cancer patients post-thyroidectomy. Methods In this retrospective study, 18 patients diagnosed with thyroid cancer at a tertiary care hospital (Mediclinic City Hospital) in Dubai were included. The patients underwent total thyroidectomy, iodine ablation, and neck ultrasound...
December 2023: Curēus
https://read.qxmd.com/read/38256549/thyroid-disorders-in-systemic-sclerosis-a-comprehensive-review
#28
REVIEW
Aifer Cherim, Răzvan-Cosmin Petca, Mihai-Cristian Dumitrascu, Aida Petca, Elisabeta Candrea, Florica Sandru
Systemic sclerosis, also referred to as scleroderma, is a chronic autoimmune disease that affects both internal organs and the skin. Systemic sclerosis predominantly affects female patients and can coexist with other disorders, including those affecting the thyroid gland. Common symptoms such as fatigue and weight changes can be attributed to either systemic sclerosis or thyroid disease. In this comprehensive review, an extensive analysis is conducted using research from 2002 to 2022, sourced from PubMed. The main focus of this exploration is to understand the intricate relationship between thyroid disorders and systemic sclerosis...
January 11, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38254799/integrated-diagnostics-of-thyroid-nodules
#29
REVIEW
Luca Giovanella, Alfredo Campennì, Murat Tuncel, Petra Petranović Ovčariček
Thyroid nodules are common findings, particularly in iodine-deficient regions. Our paper aims to revise different diagnostic tools available in clinical thyroidology and propose their rational integration. We will elaborate on the pros and cons of thyroid ultrasound (US) and its scoring systems, thyroid scintigraphy, fine-needle aspiration cytology (FNAC), molecular imaging, and artificial intelligence (AI). Ultrasonographic scoring systems can help differentiate between benign and malignant nodules. Depending on the constellation or number of suspicious ultrasound features, a FNAC is recommended...
January 11, 2024: Cancers
https://read.qxmd.com/read/38243784/selenium-supplementation-in-patients-with-hashimoto-thyroiditis-a-systematic-review-and-meta-analysis-of-randomized-clinical-trials
#30
JOURNAL ARTICLE
Valentina Viola Huwiler, Stephanie Maissen-Abgottspon, Zeno Stanga, Stefan Muehlebach, Roman Trepp, Lia Bally, Arjola Bano
BACKGROUND: Hashimoto thyroiditis (HT) is the most common cause of hypothyroidism in iodine-sufficient areas. Selenium is an essential trace element required for thyroid hormone synthesis and exerts antioxidant effects. Therefore, it may be of relevance in the management of HT. METHODS: We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the effect of selenium supplementation on thyroid function (thyroid-stimulating hormones [TSH], free and total thyroxine [fT4, T4], free and total triiodothyronine [fT3, T3]), thyroid antibodies (thyroid peroxidase [TPOAb], thyroglobulin [TGAb], thyrotropin receptor [TRAb]), ultrasound findings (echogenicity, thyroid volume), immune markers, patient-reported outcomes, and adverse events in HT...
January 20, 2024: Thyroid: Official Journal of the American Thyroid Association
https://read.qxmd.com/read/38237505/fluoride-exposure-and-thyroid-hormone-levels-in-pregnancy-the-mirec-cohort
#31
JOURNAL ARTICLE
Meaghan Hall, Rick Hornung, Jonathan Chevrier, Pierre Ayotte, Bruce Lanphear, Christine Till
BACKGROUND: Fluoride exposure may increase the risk of hypothyroidism, but results from previous studies are inconsistent at low-level fluoride exposure (i.e., ≤0.7 mg/L). Human studies of fluoride and thyroid hormone levels in pregnancy are scarce. OBJECTIVES: We examined associations between fluoride exposure and maternal thyroid hormone levels in a Canadian pregnancy cohort, with consideration for fetal sex-specific effects. METHODS: We measured fluoride concentrations in drinking water and spot urine samples collected during each trimester from 1876 pregnant women enrolled in the Maternal-Infant Research on Environmental Chemicals (MIREC) study...
January 12, 2024: Environment International
https://read.qxmd.com/read/38234357/thyroid-storm-triggered-by-thyroid-nodule-fine-needle-aspiration-biopsy-a-case-report
#32
Tiffany A Eatz, Paola Rios, Carlos A Penaherrera Oviedo, Violet Lagari
BACKGROUND: Thyroid storm is a potentially fatal thyrotoxicosis triggered by an event, such as manipulation of the thyroid gland, acute iodine load, trauma, or infection. Prior to deciding on fine needle aspiration (FNA) biopsy, patients who have been diagnosed with hyperthyroidism or low thyroid stimulating hormone and multinodular goiter (MNG) should be imaged via radionuclide thyroid scan. CASE DESCRIPTION: We present a case of a 62-year-old female patient with history of MNG, who had thyrotoxicosis on presentation due to medication noncompliance and was found to have Graves' disease...
2024: AME Case Reports
https://read.qxmd.com/read/38221821/study-of-iodine-transport-and-thyroid-hormone-levels-in-the-human-placenta-under-different-iodine-nutritional-status
#33
JOURNAL ARTICLE
Min Fu, Zhiyuan Ren, Yuanpeng Gao, Haixia Zhang, Wenxing Guo, Wanqi Zhang
Iodine and thyroid hormones (THs) transport in the placenta are essential for fetal growth and development, but there is little research focus on the human placenta. The research aimed to investigate iodine and THs transport mechanisms in the human placenta. The placenta was collected from 60 healthy pregnant women. Urinary iodine concentration (UIC), serum iodine concentration (SIC), placenta iodine storage (PIS), and the concentration of serum and placenta THs were examined. 5 pregnant women were selected as insufficient intake (II), adequate intake (AI), and above requirements intake (ARI) groups respectively...
January 15, 2024: British Journal of Nutrition
https://read.qxmd.com/read/38212512/retrospective-case-control-study-examining-the-relationship-between-recurrence-free-survival-and-changes-in-pre-and-post-radioiodine-therapy-serum-thyroglobulin-levels-in-patients-with-differentiated-thyroid-cancer
#34
JOURNAL ARTICLE
Ken Watanabe, Takao Igarashi, Mayuki Uchiyama, Takayuki Ishigaki, Hiroya Ojiri
PURPOSE: Thyroglobulin assay is important to assess the residual or recurrence of differentiated thyroid cancer (DTC). Patients with positive serum thyroglobulin levels after radioactive iodine (RAI) adjuvant therapy could achieve long-term recurrence-free survival (RFS). The patient's prognosis could not be confidently estimated based solely on the evaluation of thyroglobulin levels. We investigated the recurrence rate and RFS of patients who received adjuvant RAI therapy after surgery for DTC to clarify the relationship between changes in pre- and post-therapy serum thyroglobulin levels and RFS...
January 12, 2024: Japanese Journal of Radiology
https://read.qxmd.com/read/38206745/effects-of-vitamin-d-supplementation-on-autoantibodies-and-thyroid-function-in-patients-with-hashimoto-s-thyroiditis-a-systematic-review-and-meta-analysis
#35
JOURNAL ARTICLE
Jiahao Tang, Shuanghong Shan, Fangping Li, Peng Yun
BACKGROUND: Hashimoto's thyroiditis (HT) is the prevailing form of autoimmune thyroiditis and the leading cause of hypothyroidism in iodine-sufficient regions worldwide. This study aims to evaluate the efficacy of vitamin D supplementation on HT through a meta-analysis of randomized controlled trials (RCTs). METHODS: The databases searched included PubMed, and others. We included RCTs that the treatment group received vitamin D, while the control group received either a placebo or no treatment...
December 29, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/38191240/antenatal-screening-for-thyroid-dysfunction-pre-term-birth-low-birth-weight-and-growth-restriction
#36
JOURNAL ARTICLE
Ishraq Dhaifalah, Jana Havalova, Dagmar Langova, Howard Cuckle
OBJECTIVE: To assess pre-term birth, low birth-weight and growth restriction according to maternal thyroid screening results and subsequent treatment. METHODS: This is a nonintervention nested case-control study derived from 10,052 asymptomatic women previously screened during the first trimester marker with anti-thyroid peroxidase antibodies, serum thyroid stimulating hormone, and free thyroxine. Screening results had been classified as positive with one or more markers outside the normal range and referred to an endocrinologist...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38182855/clinical-use-of-thyroglobulin-not-only-thyroid-cancer
#37
REVIEW
Berlińska Agata, Świątkowska-Stodulska Renata
Thyroglobulin (TG) is a dimeric glycoprotein produced exclusively by mature thyroid tissue and stored within the follicular lumen. It is essential for the organification of iodine and the production of thyroid hormones. The concentration of TG in the bloodstream varies between individuals and depends on factors such as thyroid mass, stimulation of the gland by thyrotropin or autoantibodies, and tissue destruction. TG is essential to monitor patients with differentiated thyroid cancer; however, its use is not limited only to this clinical entity...
January 6, 2024: Endocrine
https://read.qxmd.com/read/38167020/effects-of-altitude-on-thyroid-disorders-according-to-chinese-three-rung-ladder-like-topography-national-cross-sectional-study
#38
JOURNAL ARTICLE
Boshen Gong, Youmin Wang, Jin-An Zhang, Qiao Zhang, Jiajun Zhao, Jiashu Li, Xichang Wang, Yutong Han, Ziwei Yu, Chenyu Zhang, Bingcong Peng, Yumin Xing, Qiuxian Li, Ping Wang, Yongze Li, Weiping Teng, Zhongyan Shan
BACKGROUND: Chinese topography appears a three-rung ladder-like distribution of decreasing elevation from northwest to southeast, which is divided by two sloping edges. Previous studies have reported that prevalence of thyroid diseases differed by altitude, and geographical factors were associated with thyroid disorders. To explore the association between three-rung ladder-like regions and thyroid disorders according to unique Chinese topographic features, we conducted an epidemiological cross-sectional study from 2015-2017 that covered all 31 mainland Chinese provinces...
January 2, 2024: BMC Public Health
https://read.qxmd.com/read/38164565/diagnostic-performance-of-18-f-tfb-pet-ct-compared-with-therapeutic-activity-131-i-iodine-spect-ct-and-18-f-fdg-pet-ct-in-recurrent-differentiated-thyroid-carcinoma
#39
JOURNAL ARTICLE
David Ventura, Matthias Dittmann, Florian Büther, Michael Schäfers, Kambiz Rahbar, Daniel Hescheler, Michael Claesener, Philipp Schindler, Burkhard Riemann, Robert Seifert, Wolfgang Roll
[18 F]tetrafluoroborate ([18 F]TFB) is an emerging PET tracer with excellent properties for human sodium iodide symporter (NIS)-based imaging in patients with differentiated thyroid cancer (DTC). The aim of this study was to compare [18 F]TFB PET with high-activity posttherapeutic [131 I]iodine whole-body scintigraphy and SPECT/CT in recurrent DTC and with [18 F]FDG PET/CT in suspected dedifferentiation. Methods: Twenty-six patients treated with high-activity radioactive [131 I]iodine therapy (range, 5.00-10...
December 21, 2023: Journal of Nuclear Medicine
https://read.qxmd.com/read/38141138/iodine-intake-in-the-swiss-population-100%C3%A2-years-after-the-introduction-of-iodised-salt-a-cross-sectional-national-study-in-children-and-pregnant-women
#40
JOURNAL ARTICLE
Lena Fischer, Maria Andersson, Christian Braegger, Isabelle Herter-Aeberli
PURPOSE: The Swiss voluntary salt iodisation programme has successfully prevented iodine deficiency for 100 years, but dietary habits are changing and today only one-third of processed foods contain iodised salt. We aimed to monitor the current iodine status in children and pregnant women. METHODS: We conducted a nationwide cross-sectional study in children (6-12 years) and pregnant women and measured the urinary iodine concentration (UIC) in spot urine samples...
December 23, 2023: European Journal of Nutrition
keyword
keyword
80229
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.