keyword
https://read.qxmd.com/read/37116038/chronic-liver-disease-secondary-to-chronic-budd-chiari-causing-osteomalacia-leading-to-pathological-fractures
#21
JOURNAL ARTICLE
Bhagyavardhan Singh, Gupta, N Hooda, S Baidya
INTRODUCTION: Metabolic disturbances of bone are common in patients of CLD manifesting as osteoporosis and osteopenia while osteomalacia is rare. MATERIALS: 34 years old lady with history of portal vein thrombosis and CLD since 2008 presented with complaints of anorexia, early satiety, nausea, vomiting weight loss for 8 months and syncopal attack followed by fall on ground leading to multiple fractures in both lower limbs and left upper limb. Investigations including hemogram, metabolic profile, X-rays, anemia workup, Vitamin D3, parathyroid hormone (PTH), hormone profile, CA-125, 24-hour urinary calcium, USG were planned...
January 2023: Journal of the Association of Physicians of India
https://read.qxmd.com/read/37105943/combined-levothyroxine-and-testosterone-treatment-for-restoring-erectile-dysfunction-in-propylthiouracil-induced-hypothyroid-rats
#22
JOURNAL ARTICLE
Fatma Nur Korkmaz, Didem Yilmaz-Oral, Heba Asker, Berna Guven, Damla Turkcan, Omer Faruk Kirlangic, Cetin Volkan Oztekin, Demet Çorapçıoğlu, Özgür Demir, Ilker Ates, Serap Gur
BACKGROUND: Sexual dysfunction may indicate severe endocrine diseases. Recent research has suggested a link between hypothyroidism, low testosterone (T) levels, and erectile dysfunction (ED); however, the exact cause is unknown. AIM: We sought to investigate possible beneficial effects of levothyroxine and T alone or in combination on ED in propylthiouracil (PTU)-induced hypothyroid rats. METHODS: Adult Wistar rats (n = 35) were divided into 5 groups: control, PTU-induced hypothyroidism, PTU + levothyroxine, PTU + Sustanon (a mixture of 4 types of T: propionate, phenylpropionate, isocaproate, and decanoate) and PTU + levothyroxine + Sustanon...
April 27, 2023: Journal of Sexual Medicine
https://read.qxmd.com/read/37104906/comparison-of-the-effect-of-quercetin-and-daidzein-on-production-performance-anti-oxidation-hormones-and-cecal-microflora-in-laying-hens-during-the-late-laying-period
#23
JOURNAL ARTICLE
Jiayan Liu, Yuxin Fu, Shuaishuai Zhou, Pengyu Zhao, Jian Zhao, Qinglin Yang, Hao Wu, Manyi Ding, Yao Li
This study aims to compare the effect of quercetin and daidzein on production performance, anti-oxidation, hormones, and cecal microflora in laying hens during the late laying period. A total of 360 53-week-old healthy Hyline brown laying hens were randomly divided into 3 groups (control, 0.05% quercetin, and 0.003% daidzein). Diets were fed for 10 wk, afterwards 1 bird per replicate (6 replicates) were euthanized for sampling blood, liver and cecal digesta. Compared with the control, quercetin significantly increased laying rate and decreased feed-to-egg weight ratio from wk 1 to 4, wk 5 to 10, and wk 1 to 10 (P < 0...
March 27, 2023: Poultry Science
https://read.qxmd.com/read/37002642/bps-induced-ovarian-dysfunction-protective-actions-of-melatonin-via-modulation-of-sirt-1-nrf2-nf%C3%A4-b-and-ir-pi3k-pakt-glut-4-expressions-in-adult-golden-hamster
#24
JOURNAL ARTICLE
Sriparna Pal, Aishwarya Sahu, Rakesh Verma, Chandana Haldar
Ever-increasing occurrence of plastic-manufacturing industries leads to environmental pollution that has been associated with declined human health and increased incidence of compromised reproductive health. Female subfertility/infertility is a complex phenomenon and environmental toxicants as well as lifestyle factors have a crucial role to play. Bisphenol S (BPS) was believed to be a "safer" replacement of bisphenol A (BPA) but recent data documented its neurotoxic, hepatotoxic, nephrotoxic, and reprotoxic attributes...
March 31, 2023: Journal of Pineal Research
https://read.qxmd.com/read/36848018/bone-mineral-density-vertebral-fractures-and-trabecular-bone-score-in-primary-ovarian-insufficiency
#25
JOURNAL ARTICLE
M Dhakate, D Goswami, R Goswami, S Saha, D Kandasamy, M Arora
PURPOSE: Bone health in primary ovarian insufficiency (POI) is under-investigated. We assessed patients with spontaneous POI for vertebral fractures (VFs) and related parameters of bone health. METHODS: 70 cases with spontaneous POI (age 32.5 ± 7.0 years) and an equal number of controls were assessed for BMD, TBS, and VFs. BMD at the lumbar-spine (L1-L4), left hip, non-dominant forearm, and TBS (iNsight software) were measured on a dual-energy X-ray absorptiometry (DXA) machine...
February 27, 2023: Journal of Endocrinological Investigation
https://read.qxmd.com/read/36843696/endocrine-abnormalities-in-children-with-traumatic-brain-injury-at-a-tertiary-care-center
#26
JOURNAL ARTICLE
Aaida Rao, Altaf Ali Laghari, Iman Bari, Muhammad Usman Khalid, Salman Kirmani, Muhammad Ehsan Bari
Objective Accidental traumatic brain injury (TBI) can lead to severe complications such as endocrine abnormalities and long-term morbidities and can negatively impact patient lives. These conditions are also associated with a high cost of treatment over a lifetime, a significant concern in low-to-middle-income countries (LMICs). In Pakistan, the prevalence of children with endocrine abnormalities secondary to TBI remains largely unexplored. We conducted a retrospective cross-sectional study to estimate the burden of endocrine abnormalities due to TBI among children in our population...
January 2023: Curēus
https://read.qxmd.com/read/36774403/cystic-versus-non-cystic-silent-corticotrophic-adenomas-clinical-and-histological-analysis-of-62-cases-after-microscopic-transsphenoidal-surgery-a-retrospective-single-center-study
#27
JOURNAL ARTICLE
Piotr Sumislawski, Torge Huckhagel, Kara Leigh Krajewski, Jens Aberle, Wolfgang Saeger, Jörg Flitsch, Roman Rotermund
Silent corticotrophic adenomas (SCAs) represent a rare group of non-functioning adenomas with a potentially aggressive clinical course. Cystic component is a very common finding among SCAs, but its clinical relevance has not yet been investigated. The aim of this study was to analyze clinical features of cystic and non-cystic SCAs, perioperative complications after microscopic transsphenoidal surgery, clinical outcome after first and repeat surgery along with risk factors for recurrence. We conducted a retrospective analysis of 62 silent corticotrophic adenomas treated at our university medical center via microscopic transsphenoidal surgery between January 2008 and July 2019...
February 11, 2023: Scientific Reports
https://read.qxmd.com/read/36762334/assessment-of-thyroid-function-tests-in-patients-with-chronic-obstructive-pulmonary-disease
#28
JOURNAL ARTICLE
Ali Hasan Ismaeel Alshamari, Falah Deli, Hesham Ibrahim Kadhum, Iman Jabar Kadhim
Chronic obstructive pulmonary disease (COPD), a group of diseases of distinct aetio-pathological consideration with different phenotypic presentations where smoking is the leading cause, all share the ultimate result of airflow limitation. This study aimed to evaluate thyroid function tests (TFT) in patients with COPD. Pulmonary function tests (PFT) were performed for 30 patients with obstructive lung disease and fifteen healthy control individuals. We measured SPO2 to confirm COPD and assess the severity of the disease and assessed TT3, TT4, and TSH using the ELISA test...
December 2022: Journal of Medicine and Life
https://read.qxmd.com/read/36640628/flaxseed-oil-modulates-testicular-biometrics-hormone-libido-antioxidant-and-semen-profiles-in-endangered-teressa-goat-of-andaman-and-nicobar-islands
#29
JOURNAL ARTICLE
P Perumal, Jai Sunder, A K De, R R Alyethodi, R Vikram, V R Upadhyay, S C Mayuri, D Bhattacharya
Teressa goat is a unique goat breed in Andaman and Nicobar Islands (ANI) of India. Effects of Flaxseed oil (FSO) supplementation in body weight (BW), scrotal circumference (SC), testicular volume (TV) and testicular weight (TW), endocrinological profiles, sex behavioural profiles (SBPs), oxidative stress markers and semen production and its quality profiles in rainy and dry summer season were studied in Teressa goat. Male goats (n = 12) of 3-4 years old were equally divided into control and treated groups...
January 12, 2023: Reproductive Biology
https://read.qxmd.com/read/36509348/acute-exposure-to-microcystins-affects-hypothalamic-pituitary-axes-of-male-rats
#30
JOURNAL ARTICLE
Ting Shi, Lin-Lin Xu, Liang Chen, Jun He, Ye-Ke Wang, Feng Chen, Yang Chen, John P Giesy, Yu-Ting Wang, Qian-Hui Wu, Wen-Li Xu, Jun Chen, Ping Xie
Microcystins (MCs) produced by some cyanobacteria can cause toxicity in animals and humans. In recent years, growing evidence suggests that MCs can act as endocrine disruptors. This research systematically investigated effects of microcystin-LR (MC-LR) on endocrine organs, biosynthesis of hormones and positive/negative feedback on the endocrine system in rats. Male, Sprague-Dawley rats were acutely administrated MC-LR by a single intraperitoneal injection at doses of 45, 67.5 or 90 μg MC-LR/kg body mass (bm), and then euthanized 24 h after exposure...
December 9, 2022: Environmental Pollution
https://read.qxmd.com/read/36504854/reproductive-performance-of-zi-goose-promoted-by-red-color-illumination
#31
JOURNAL ARTICLE
Manyu Li, Chen Liang, Xiuhua Zhao, Guojun Liu, Yuanliang Zhang, Shan Yue, Zhiqiang Zhang
The color of light affects the reproductive performance of poultry, but it is not clear what efficient illumination strategy could be adopted to improve the reproductive performance of Zi-goose. Red light can increase the average weekly egg production rate, egg production, and qualified production. It can increase the serum GnRH level and decrease the serum PRL, MT, and T4 levels. In our study, red light for 12 h increased the average weekly laying rate, average qualified egg production, and hatching rate of Zi-goose eggs, and increased the serum levels of FSH, LH, P4, E2, MT, T3, and T4...
2022: Frontiers in Veterinary Science
https://read.qxmd.com/read/36188647/comparative-characteristics-of-infertile-women-when-applying-melatonin-in-complex-preparation-for-assisted-reproductive-technologies
#32
JOURNAL ARTICLE
Viktoria Olexandrivna Yuzko, Olexandr Mykhailovych Yuzko, Tamara Anatoliivna Yuzko, Svitlana Hryhorivna Pryimak, Natalia Serhiivna Voloshynovych, Svitlana Ivanivna Chobaniuk
A retrospective analysis of medical records of infertile patients using assisted reproductive technologies and melatonin was performed. 76 infertile women were examined. Group 1 included 33 patients who received 3 mg of melatonin two weeks before and during ovulation induction, and group 2 included 43 patients who did not take melatonin. The average age of patients in the groups did not differ. The data of gynecological and ultrasound examinations, structure and thickness of the endometrium, antral follicle count, hormone levels: anti-mullerian, follicle-stimulating, luteinizing, progesterone, estradiol, prolactin, thyrotropin, and thyroxine were evaluated...
August 2022: Journal of Medicine and Life
https://read.qxmd.com/read/36187113/intrathyroidal-feedforward-and-feedback-network-regulating-thyroid-hormone-synthesis-and-secretion
#33
REVIEW
Li Jing, Qiang Zhang
Thyroid hormones (THs), including T4 and T3, are produced and released by the thyroid gland under the stimulation of thyroid-stimulating hormone (TSH). The homeostasis of THs is regulated via the coordination of the hypothalamic-pituitary-thyroid axis, plasma binding proteins, and local metabolism in tissues. TH synthesis and secretion in the thyrocytes-containing thyroid follicles are exquisitely regulated by an elaborate molecular network comprising enzymes, transporters, signal transduction machineries, and transcription factors...
2022: Frontiers in Endocrinology
https://read.qxmd.com/read/36185961/clinical-profile-and-molecular-genetic-analysis-of-prader-willi-syndrome-a-single-center-experience
#34
JOURNAL ARTICLE
Subbiah Sridhar, Roshan Nazirudeen, Suresh Ramasamy, Vasanthiy Natarajan, Kumanan Thiagarajan, Lakshmanan Nivethitha Karthika
AIM: The prevalence of childhood and adolescent obesity is increasing worldwide as well as in India. Prader--Willi syndrome (PWS) is one of the most common causes of syndromic obesity with varied clinical manifestations across different lifespan. Herewith, we describe clinical and molecular characteristics of eight PWS who were diagnosed in an obesity clinic of tertiary care hospital. MATERIALS AND METHODS: Clinically suspected cases of PWS were screened between January 2014 and January 2022...
2022: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/35975253/anti-thyroid-antibodies-and-the-gonadotrophins-profile-lh-fsh-in-euthyroid-polycystic-ovarian-syndrome-women
#35
EDITORIAL
M Sharma, A Modi, M Goyal, P Sharma, P Purohit
CONTEXT: The current study aimed to determine association of anti-TPO with LH/FSH in PCOS women. DESIGN: Current case control study included 33 diagnosed PCOS women and 32 age matched healthy women and were analysed for body mass index (BMI) and waist to hip ratio (WHR), fasting blood glucose (FBG), free T3 (FT3), free T4 (FT4), Thyroid stimulating hormone (TSH), dehydroepiandrostenedione (DHEA-S), total testosterone, follicular stimulating hormone (FSH), luteinizing hormone (LH) and anti thyroperoxidase antibodies (anti-TPO)...
2022: Acta endocrinologica: the international journal of the Romanian Society of Endocrinology
https://read.qxmd.com/read/35965323/evaluation-of-anti-m%C3%A3-llerian-hormone-in-pre-menopausal-women-stratified-according-to-thyroid-function-autoimmunity-and-age
#36
JOURNAL ARTICLE
Massimo Giusti, Miranda Mittica
BACKGROUND: AMH is a reliable index of ovarian reserve. It is not clear whether, or how much, thyroid function and/or thyroid autoimmunity can impair ovarian function and AMH secretion in the long term. AIM: This retrospective cross-sectional study compared AMH levels in pre-menopausal women with/without positive thyroid autoimmunity or hypofunction. METHODS: From January 2019 to May 2022, AMH was evaluated in 250 pre-menopausal women not undergoing assisted fertility procedures who were referred to a secondary endocrine centre...
August 15, 2022: Thyroid Research
https://read.qxmd.com/read/35544473/a-randomized-clinical-trial-demonstrating-cell-type-specific-effects-of-hyperlipidemia-and-hyperinsulinemia-on-pituitary-function
#37
JOURNAL ARTICLE
Rosemary McDonald, Katherine Kuhn, Thy B Nguyen, Andrew Tannous, Irene Schauer, Nanette Santoro, Andrew P Bradford
INTRODUCTION: Obesity is characterized by elevated lipids, insulin resistance and relative hypogonadotropic hypogonadism, reducing fertility and increasing risk of pregnancy complications and birth defects. We termed this phenotype 'Reprometabolic Syndrome' and showed that it can be recapitulated by acute infusions of lipid/insulin into healthy, normal weight, eumenorrheic women. Herein, we examined the broader impact of hyperlipidemia and euglycemic hyperinsulinemia on anterior pituitary trophic hormones and their targets...
2022: PloS One
https://read.qxmd.com/read/35468440/acute-nitrite-exposure-interferes-with-intestinal-thyroid-hormone-homeostasis-in-grass-carp-ctenopharyngodon-idellus
#38
JOURNAL ARTICLE
Xiao Liang, Yin Wang, Lu Liu, Xi Zhang, Li Li, Rong Tang, Dapeng Li
Nitrite in the aquatic environment potentially disturbs thyroid hormone (TH) homeostasis in peripheral tissues, but little is known about TH metabolism in the intestine. This study investigated the serum concentrations of THs and thyroid-stimulating hormone (TSH) as well as the activity of intestinal iodothyronine deiodinases (IDs) of grass carp (Ctenopharyngodon idellus) exposed to various concentrations of nitrite (0, 8, 25, or 50 mg/L) for 96 h. Acute nitrite exposure significantly altered the triiodothyronine (T3) levels and the morphology of thyroid follicles at 96 h...
April 22, 2022: Ecotoxicology and Environmental Safety
https://read.qxmd.com/read/34941101/slipped-capital-femoral-epiphysis-with-hypopituitarism-in-adults-a-case-report-and-literature-review
#39
JOURNAL ARTICLE
Zhixin Niu, Jinshuo Tang, Xianyue Shen, Shenghao Xu, Zhongsheng Zhou, Tong Liu, Jianlin Zuo
RATIONALE: Slipped capital femoral epiphysis (SCFE) is a common disease in pediatric orthopedics. Most research on SCFE has focused on high-risk groups or the whole population, and studies focusing on adult SCFE patients are rare. In the present study, we report the case of an adult patient with SCFE. PATIENT CONCERN: A 37-year-old man presented to our clinic with persistent pain that was poorly localized to both hips, groin regions, and thighs for more than 1 year...
December 23, 2021: Medicine (Baltimore)
https://read.qxmd.com/read/34815838/season-influence-on-serum-kisspeptin-level-and-its-association-with-hormonal-levels-and-semen-kinematics-of-buffalo-bulls-bubalus-bubalis
#40
JOURNAL ARTICLE
Muhammad Khurram Shahzad, Imtiaz Rabbani, Sayed Murtaza Hassan Andrabi, Hafsa Zaneb, Muhammad Shahbaz Yousaf, Khalid Abdul Majeed, Sajid Khan Tahir, Sohrab Ahmad, Habib Rehman
Kisspeptin has an important role in the stimulation of hypothalamic-pituitary-gonadal axis in term of pubertal development, release of reproductive and metabolic hormones and ultimately affecting the fertility. The aim of the present study was to evaluate the serum kisspeptin level and its correlation with semen quality and selected hormones in buffalo bulls during the summer and spring seasons. Semen and blood samples from eight Nili-Ravi buffalo bulls (age: 9.21 ± 1.02 years) were collected. Semen was analysed using computer-assisted semen analysis...
2021: Veterinary Research Forum
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