keyword
MENU ▼
Read by QxMD icon Read
search

Herv

keyword
https://www.readbyqxmd.com/read/29135905/unsuccessful-suicide-attempt-with-tiapride
#1
Sylvain Couderc, Hervé Mourou, Caroline Monchaud, Franck Saint-Marcoux
To the best of our knowledge, no case has been published in the literature that reports an overdose of tiapride, either alone or in combination with other drugs. We report a self-poisoning case in an 18-year-old girl, with approximately 10 times the usual daily dose (ie, 2.5 g). Although the blood concentration was 20/30-fold higher than usually observed after therapeutic drug intakes (17,300 mcg/L), the patient remained almost asymptomatic.
December 2017: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/29135797/use-of-a-threshold-of-interleukin-10-and-il-10-il-6-ratio-in-ocular-samples-for-the-screening-of-vitreoretinal-lymphoma
#2
Celine Pochat-Cotilloux, Jacques Bienvenu, Anh-Minh Nguyen, Robin Ohanessian, Hervé Ghesquières, Pascal Sève, Lorna Garnier, Laurent Kodjikian
PURPOSE: To determine a threshold for interleukin (IL)-10 and IL-10/IL-6 ratio in the aqueous humor (AH) and the vitreous for the screening of vitreoretinal lymphoma (VRL). METHODS: One hundred nineteen patients for whom IL-10 and IL-6 in the AH and/or vitreous had been measured were included: 16 patients with a final diagnosis of VRL and 103 patients with final diagnosis of uveitis. Groups were compared according to IL-10 and IL-6 levels and demographic data. RESULTS: In patients with VRL (Group 1), mean IL-10 values were 5,636 pg/mL, and in patients with uveitis (Group 2), 6...
November 10, 2017: Retina
https://www.readbyqxmd.com/read/29134568/%C3%AE-2-adrenergic-stimulation-of-dendritic-cells-favors-il-10-secretion-by-cd4-t-cells
#3
Julie Hervé, Karine Haurogné, Elodie Bacou, Sylvie Pogu, Marie Allard, Grégoire Mignot, Jean-Marie Bach, Blandine Lieubeau
Adrenergic receptor agonists and antagonists are extensively used as drugs in medicine for a broad spectrum of indications. We examined the consequences of β2-adrenergic stimulation of murine dendritic cells (DCs) on CD4(+) T cell activation. We demonstrated in vitro that treatment of LPS-matured DCs with the β2-agonist salbutamol reduced their ability to trigger OT-II T cell proliferation specific for ovalbumin antigen. Salbutamol also induced a decrease in MHC class II molecule expression by DC through Gi protein activation...
November 14, 2017: Immunologic Research
https://www.readbyqxmd.com/read/29133198/study-of-the-mechanical-reliability-of-an-s-shaped-adjustable-osteosynthesis-plate-for-bilateral-sagittal-split-osteotomies-study-on-15-consecutive-cases
#4
Alexis Veyssiere, Nicols Leprovost, Béatrice Ambroise, Raphaelle Prévost, Anne Chatellier, Hervé Bénateau
INTRODUCTION: The main challenge during the osteosynthesis of a bilateral sagittal split osteotomy (BSSO) is to take into account the correct position of the condyle. Adjustable plates can be used to fine-tune the final occlusion without changing the osteosynthesis. A new type of adjustable plate is presented in this article. The aim is to assess the mechanical reliability of this system during the surgery and during the healing period, thanks to a preliminary prospective on 15 consecutive cases...
November 10, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29133025/perivalvular-mitral-abscess-fistulised-to-the-pericardial-cavity-revealing-staphylococcal-endocarditis
#5
Paul Desaint, Anthony Chauvat, Thomas Garaud, Olivier Andremont, Gaëtan Plantefève, Hervé Mentec, Damien Contou
BACKGROUND: Fistula to the pericardial cavity is a very rare complication of perivalvular abscess during infective endocarditis, with Staphylococcus aureus being the most commonly associated microorganism. METHODS: We report a fatal septic shock due to a mitral endocarditis revealed by a myocardial abscess fistulised toward the pericardial cavity. RESULTS: A 66-year-old female without previous valvular disease was admitted to intensive care for severe sepsis...
October 31, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29129434/mutational-landscape-of-ddr2-gene-in-lung-squamous-cell-carcinoma-using-next-generation-sequencing
#6
Charles Ricordel, Alexandra Lespagnol, Francisco Llamas-Gutierrez, Marie de Tayrac, Mallorie Kerjouan, Alice Fievet, Houda Hamdi-Rozé, Amyrat Aliouat, Benoit Desrues, Jean Mosser, Hervé Léna
BACKGROUND: Lung cancer represents the leading cause of cancer-related death worldwide. Despite great advances in lung cancer management with the recent emergence of molecular targeted therapies for non-squamous non-small-cell lung cancer, no dramatic improvements have been achieved in lung squamous cell carcinoma (SCC). Mutations in discoidin domain receptor 2 (DDR2) gene were recently identified as promising molecular targets in this histology. The aim of this study is to describe the DDR2 mutational landscape of lung SCC and investigate the associated clinical factors...
October 19, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/29127624/evidence-from-the-gut-microbiota-of-swarming-alates-of-a-vertical-transmission-of-the-bacterial-symbionts-in-nasutitermes-arborum-termitidae-nasutitermitinae
#7
Michel Diouf, Vincent Hervé, Philippe Mora, Alain Robert, Sophie Frechault, Corinne Rouland-Lefèvre, Edouard Miambi
Studies on termite symbiosis have revealed that significant symbiont lineages are maintained across generations. However, most studies have focused only on the worker caste. Little is known about the gut microbiota of reproductives, the most probable vectors for transmitting these lineages to offspring. Using 16S rRNA gene-based Illumina MiSeq sequencing, we compared the gut microbiota of swarming alates of the higher termite Nasutitermes arborum with those of their nestmates from the parental colony. The OTU-based alpha diversity indices showed that the gut microbiota of the alates was at least as diverse as those of non-reproductive adults...
November 10, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29125089/the-development-of-determiners-in-the-context-of-french-english-bilingualism-a-study-of-cross-linguistic-influence
#8
Coralie Hervé, Ludovica Serratrice
This paper reports the preliminary results of a study examining the role of structural overlap, language exposure, and language use on cross-linguistic influence (CLI) in bilingual first language acquisition. We focus on the longitudinal development of determiners in a corpus of two French-English children between the ages of 2;4 and 3;7. The results display bi-directional CLI in the rate of development, i.e., accelerated development in English and a minor delay in French. Unidirectional CLI from English to French was instead observed in the significantly higher rate of ungrammatical determiner omissions in plural and generic contexts than in singular specific contexts in French...
November 10, 2017: Journal of Child Language
https://www.readbyqxmd.com/read/29122847/human-airway-trypsin-like-protease-exerts-potent-antifibrotic-action-in-pulmonary-fibrosis
#9
Awen Menou, Pauline Flajolet, JanWillem Duitman, Aurélien Justet, Sophie Moog, Madeleine Jaillet, Laure Tabèze, Brigitte Solhonne, Marc Garnier, Hervé Mal, Pierre Mordant, Yves Castier, Aurélie Cazes, Jean-Michel Sallenave, Arnaud A Mailleux, Bruno Crestani
Idiopathic pulmonary fibrosis (IPF) is characterized by the deposition of excessive extracellular matrix and the destruction of lung parenchyma, resulting from an aberrant wound-healing response. Although IPF is often associated with an imbalance in protease activity, the mechanisms underlying the sustained repair mechanisms are not fully understood. Here, we addressed the role of the recently identified, membrane-anchored serine protease human airway trypsin-like protease (HAT). In the present study, we show that both HAT expression and activity were up-regulated in human IPF specimens...
November 9, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29121397/virtual-phantom-magnetic-resonance-imaging-vip-mri-on-a-clinical-mri-platform
#10
Hervé Saint-Jalmes, Alejandro Bordelois, Giulio Gambarota
PURPOSE: To implement Virtual Phantom Magnetic Resonance Imaging (ViP MRI), a technique that allows for generating reference signals in MR images using radiofrequency (RF) signals, on a clinical MR system and to test newly designed virtual phantoms. METHODS: MRI experiments were conducted on a 1.5 T MRI scanner. Electromagnetic modelling of the ViP system was done using the Principle of Reciprocity. The ViP RF signals were generated using a compact waveform generator (dimensions of 26cm x 18cm x 16cm), connected to a home-built 25mm-diameter RF coil...
November 9, 2017: Medical Physics
https://www.readbyqxmd.com/read/29120974/plasma-7-hydroxymethotrexate-levels-versus-methotrexate-to-predict-delayed-elimination-in-children-receiving-high-dose-methotrexate
#11
Nicolas Fabresse, Bénédicte Devictor, Christel Pissier, Hervé Chambost, Bruno Lacarelle, Gérard Michel, Caroline Solas
BACKGROUND: The aim of this study was to investigate the correlation between 7-hydroxymethotrexate (7-OHMTX) and creatinine and to evaluate the predictive value of 7-OHMTX levels on delayed elimination at 24 and 48 hours. In addition, differences in methotrexate (MTX), 7-OHMTX levels, and MTX metabolism using the ratio MTX/7-OHMTX were determined according to age. METHODS: The authors included a total of 106 cycles, corresponding to 33 patients (mean age: 9.8 years, range: 2-18 years) suffering from acute lymphoblastic leukemia, non-Hodgkin lymphoma and osteosarcoma and receiving high-dose MTX (HD-MTX)...
November 8, 2017: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/29120620/on-the-limits-in-size-of-taylor-dispersion-analysis-representation-of-the-different-hydrodynamic-regimes-and-application-to-the-size-characterization-of-cubosomes
#12
Joseph Chamieh, Laurent Leclercq, Michel Martin, Sofia Slaoui, Henrik Jensen, Jesper Ostergaard, Hervé Cottet
Taylor Dispersion Analysis (TDA) is an absolute method (no calibration needed) for the determination of the molecular diffusion coefficient (D) based on the band broadening of a solute in a laminar flow. TDA is virtually applicable to any solute with size ranging from angstrom to sub-micron. The higher sizing limit is restricted by the occurrence of possibly two regimes: convective and hydrodynamic chromatography (HDC) regimes, which have different physical origins that should not be confused. This work aims at clearly defining the experimental conditions for which these two regimes can play a role, alone or concomitantly...
November 9, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29119060/intra-abdominal-hypertension-in-severe-burns-prevalence-incidence-and-mortality-in-a-sub-saharan-african-hospital
#13
Ronald Mbiine, Rose Alenyo, Olive Kobusingye, Job Kuteesa, Cephas Nakanwagi, Hervé Monka Lekuya, Olivia Kituuka, Moses Galukande
BACKGROUND: Severe burns have been shown to be a risk factor for developing intra-abdominal hypertension (IAH). Fluid resuscitation practices used in burns management further predispose patients to intra-abdominal hypertension. The mortality associated with IAH in severe burns is estimated to be more than 74.5% once organ dysfunction occurs. Despite 95% of all burns occurring in Low and Middle income countries (LMIC), there is paucity of published data on this topic in sub-Saharan Africa...
2017: International Journal of Burns and Trauma
https://www.readbyqxmd.com/read/29118853/identification-of-a-novel-herv-k-hml10-comprehensive-characterization-and-comparative-analysis-in-non-human-primates-provide-insights-about-hml10-proviruses-structure-and-diffusion
#14
Nicole Grandi, Marta Cadeddu, Maria Paola Pisano, Francesca Esposito, Jonas Blomberg, Enzo Tramontano
Background: About half of the human genome is constituted of transposable elements, including human endogenous retroviruses (HERV). HERV sequences represent the 8% of our genetic material, deriving from exogenous infections occurred millions of years ago in the germ line cells and being inherited by the offspring in a Mendelian fashion. HERV-K elements (classified as HML1-10) are among the most studied HERV groups, especially due to their possible correlation with human diseases. In particular, the HML10 group was reported to be upregulated in persistent HIV-1 infected cells as well as in tumor cells and samples, and proposed to have a role in the control of host genes expression...
2017: Mobile DNA
https://www.readbyqxmd.com/read/29118217/new-breakthroughs-in-understanding-the-role-of-functional-interactions-between-the-neocortex-and-the-claustrum
#15
Solange P Brown, Brian N Mathur, Shawn R Olsen, Pierre-Hervé Luppi, Martha E Bickford, Ami Citri
Almost all areas of the neocortex are connected with the claustrum, a nucleus located between the neocortex and the striatum, yet the functions of corticoclaustral and claustrocortical connections remain largely obscure. As major efforts to model the neocortex are currently underway, it has become increasingly important to incorporate the corticoclaustral system into theories of cortical function. This Mini-Symposium was motivated by a series of recent studies which have sparked new hypotheses regarding the function of claustral circuits...
November 8, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29114019/native-elongating-transcript-sequencing-reveals-global-anti-correlation-between-sense-and-antisense-nascent-transcription-in-fission-yeast
#16
Maxime Wery, Camille Gautier, Marc Descrimes, Mayuko Yoda, Hervé Vennin-Rendos, Valérie Migeot, Daniel Gautheret, Damien Hermand, Antonin Morillon
Antisense transcription can regulate sense gene expression. However, previous annotations of antisense transcription units have been based on detection of mature antisense long non-coding (aslnc)RNAs by RNA-Seq and/or micro-arrays, only giving a partial view of the antisense transcription landscape and incomplete molecular bases for antisense-mediated regulation. Here, we used Native Elongating Transcript sequencing to map genome-wide nascent antisense transcription in fission yeast. Strikingly, antisense transcription was detected for most protein-coding genes, correlating with low sense transcription, especially when overlapping the mRNA start site...
November 7, 2017: RNA
https://www.readbyqxmd.com/read/29113817/membrane-channels-formed-by-gap-junction-proteins
#17
EDITORIAL
Jean Claude Hervé
No abstract text is available yet for this article.
November 4, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29112540/aeromedical-transport-in-children-a-descriptive-analysis-of-96-cases
#18
Guillaume Mortamet, Karen Harrington, Hervé Raffin, Mehdi Oualha, Sylvain Renolleau
OBJECTIVE: Pediatric aeromedical transport (AT) is highly challenging. We aim to describe a series of 96 cases of children requiring medical transport in terms of the indication, modalities, and related adverse events. METHODS: In this single-center retrospective study, we included air-transported patients less than 18 years old. RESULTS: During the study period, 96 patients, with median age of 120 months (range, 0-204), were air transported...
November 6, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29110511/decision-algorithms-for-the-retreatment-with-viscosupplementation-in-patients-suffering-from-knee-osteoarthritis-recommendations-from-the-european-viscosupplementation-consensus-group-eurovisco
#19
Raghu Raman, Yves Henrotin, Xavier Chevalier, Alberto Migliore, Jörg Jerosch, Jordi Montfort, Hervé Bard, Dominique Baron, Pascal Richette, Thierry Conrozier
Background Viscosupplementation (VS) is a symptomatic treatment of knee osteoarthritis. Although systematic reviews of its repeat use showed favorable benefit/risk ratio, no study has focused on the indication of retreatment. Methods A task force was created to look at issues regarding retreatment with VS in knee osteoarthritis. An attempt was made to reach consensus on several issues: (1) to define treatment "success" and "failure," (2) to determine when to retreat patients successfully treated by a previous VS, (3) to determine how to retreat patients in whom VS failed, (4) to define what to do in case of adverse reaction following previous VS, and (5) to examine the interests of soluble biomarkers to manage retreatment...
February 1, 2017: Cartilage
https://www.readbyqxmd.com/read/29109175/the-streptococcus-agalactiae-stringent-response-enhances-virulence-and-persistence-in-human-blood
#20
Thomas A Hooven, Andrew J Catomeris, Maryam Bonakdar, Luke J Tallon, Ivette Santana-Cruz, Sandra Ott, Sean C Daugherty, Hervé Tettelin, Adam J Ratner
Streptococcus agalactiae (group B Streptococcus, GBS) causes serious infection in neonates. We previously reported a Tn-seq system for performing genome-wide assessment of gene fitness in GBS. In order to identify molecular mechanisms required for GBS to transition from a mucosal commensal lifestyle to bloodstream invasion, we performed Tn-seq on GBS coincubated with human whole blood. Our analysis identified 16 genes conditionally essential for GBS survival in blood, of which 75% were members of the capsular polysaccharide (cps) operon...
November 6, 2017: Infection and Immunity
keyword
keyword
80211
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"