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https://www.readbyqxmd.com/read/28341464/reproductive-effects-of-oestrogenic-endocrine-disrupting-chemicals-in-astyanax-rivularis-inhabiting-headwaters-of-the-velhas-river-brazil
#1
André Alberto Weber, Davidson Peruci Moreira, Rafael Magno Costa Melo, Augusto Bicalho Cruz Vieira, Paula Suzanna Prado, Mirra Angelina Neres da Silva, Nilo Bazzoli, Elizete Rizzo
The Velhas River is the most polluted river in the state of Minas Gerais, south-eastern Brazil. Due to its historical and environmental relevance, the aim of this study was to evaluate the effects of oestrogenic endocrine disruptors on the reproduction of the lambari Astyanax rivularis, a small-sized species found in headwaters of the São Francisco River basin. Quarterly field samplings were carried out during a reproductive cycle in three streams of the upper Velhas River: S1 (reference site) and S2 and S3 (sites contaminated by untreated sewage)...
March 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28334719/meta-analysis-of-paediatric-patients-with-central-precocious-puberty-treated-with-intramuscular-triptorelin-11-25-mg-3-month-prolonged-release-formulation%C3%A2
#2
Adélaïde Durand, Maithé Tauber, Bharat Patel, Pascale Dutailly
BACKGROUND/AIMS: A meta-analysis was undertaken to assess the effect of triptorelin 11.25 mg 3-month prolonged-release formulation in central precocious puberty (CPP). METHODS: All available clinical studies with triptorelin 11.25 mg were included. The primary outcome was the proportion of children with suppressed luteinising hormone (LH) response (peak LH ≤3 IU/L) to the gonadotrophin-releasing hormone (GnRH) test 3 months after triptorelin 11.25 mg injection...
March 23, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28333356/the-safety-and-efficacy-of-controlled-ovarian-hyperstimulation-for-fertility-preservation-in-women-with-early-breast-cancer-a-systematic-review
#3
Rachael J Rodgers, Geoffrey D Reid, Juliette Koch, Rebecca Deans, William L Ledger, Michael Friedlander, Robert B Gilchrist, Kirsty A Walters, Jason A Abbott
STUDY QUESTION: Can controlled ovarian hyperstimulation (COH) for fertility preservation be effectively conducted in women with breast cancer without worsening their prognosis? SUMMARY ANSWER: COH with co-administration of letrozole suppresses oestradiol levels without significantly impacting oocyte yield or decreasing disease-free survival rates. WHAT IS KNOWN ALREADY: Oestradiol has the capacity to stimulate the proliferation of breast cancer cells...
February 27, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28333292/a-randomized-double-blinded-controlled-trial-of-hcg-as-luteal-phase-support-in-natural-cycle-frozen-embryo-transfer
#4
Vivian Chi Yan Lee, Raymond Hang Wun Li, William Shu Biu Yeung, H O Pak Chung, Ernest Hung Yu Ng
STUDY QUESTION: Does the use of hCG as luteal phase support in natural cycle frozen embryo transfer (FET) increase the ongoing pregnancy rate? STUDY ANSWER: The use of hCG in natural cycle FET did not improve the ongoing pregnancy rate. WHAT IS KNOWN ALREADY: The use of luteal phase support in stimulated cycles has been associated with higher live-birth rates and the results are similar when using hCG or progesterone. STUDY DESIGN SIZE, DURATION: This is a randomized double-blinded controlled trial of 450 women recruited between August 2013 and October 2015...
March 8, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28325095/concomitant-use-of-fsh-and-low-dose-recombinant-hcg-during-the-late-follicular-phase-versus-conventional-controlled-ovarian-stimulation-for-intracytoplasmic-sperm-injection-cycles
#5
Carla Andrade Rebello Iaconelli, Amanda Souza Setti, Daniela Paes Almeida Ferreira Braga, Luiz Guilherme Louzada Maldonado, Assumpto Iaconelli, Edson Borges, Tsutomu Aoki
The objective of this study was to investigate the effects of low-dose hCG supplementation on ICSI outcomes and controlled ovarian stimulation (COS) cost. Three hundred and thirty patients undergoing ICSI were split into groups according to the COS protocol: (i) control group (n = 178), including patients undergoing conventional COS treatment; and (ii) low-dose hCG group (n = 152), including patients undergoing COS with low-dose hCG supplementation. Lower mean total doses of FSH administered and higher mean oestradiol level and mature oocyte rates were observed in the low-dose hCG group...
March 22, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28321875/zygoparity-and-sex-steroid-hormone-profiles-in-bluemouth-helicolenus-dactylopterus
#6
V Sequeira, E Couto, A Neves, A R Vieira, R B Paiva, A V M Canario, L S Gordo
Two hundred and seven individuals (103 females and 104 males) of bluemouth Helicolenus dactylopterus (Scorpaeniformes, Sebastidae), a commercially important deep-water species with an unusual reproductive strategy, from the eastern Atlantic Ocean ranging from 13·9 to 37·5 cm total length (LT ) were analysed from September 2011 to October 2012. The analysis included gonad maturity phases and blood-plasma levels of oestradiol-17β (E2 ), 11-ketotestosterone (11-KT) and 17,20β-dihydroxypregn-4-en-3-one (17,20β-P)...
March 21, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28318602/metals-hormones-and-sexual-maturation-in-flemish-adolescents-in-three-cross-sectional-studies-2002-2015
#7
Sam De Craemer, Kim Croes, Nicolas van Larebeke, Stefaan De Henauw, Greet Schoeters, Eva Govarts, Ilse Loots, Tim Nawrot, Vera Nelen, Elly Den Hond, Liesbeth Bruckers, Yue Gao, Willy Baeyens
Sex hormone levels and timing of sexual maturation are considered important markers for health status of adolescents in puberty, and previous research suggests they might be influenced by metal exposure. In three campaigns of the Flemish Environment and Health Study (FLEHS I 2002-2006; FLEHS II 2007-2011 and FLEHS III 2012-2015), data were collected on internal exposure to metals (Cd, Cu, Pb, Cr, Mn, Tl, Ni, Sb, Hg, As and As species) and sexual maturation in 2671 14-15years old adolescents. All metals were measured in blood and/or urine, except total- and methylmercury which were measured in hair samples...
March 17, 2017: Environment International
https://www.readbyqxmd.com/read/28317410/sex-hormone-binding-globulin-and-antithrombin-iii-activity-in-women-with-oral-ultra-low-dose-estradiol
#8
Sumika Matsui, Toshiyuki Yasui, Kana Kasai, Kaoru Keyama, Kanako Yoshida, Takeshi Kato, Hirokazu Uemura, Akira Kuwahara, Toshiya Matsuzaki, Minoru Irahara
Oral oestrogen increases the risk of venous thromboembolism (VTE) and increases production of sex hormone-binding globulin (SHBG) in a dose-dependent manner. SHBG has been suggested to be involved in venous thromboembolism. We examined the effects of oral ultra-low-dose oestradiol on circulating levels of SHBG and coagulation parameters, and we compared the effects to those of transdermal oestradiol. Twenty women received oral oestradiol (500 μg) every day (oral ultra-low-dose group) and 20 women received a transdermal patch (50 μg) as a transdermal group...
March 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28296530/early-post-haemorrhagic-stroke-testosterone-and-oestradiol-levels-and-long-term-risk-of-death
#9
Jing Cai, Jingbo Li, Shuda Chen, Jing Meng, Reng Ren, Min Li
OBJECTIVE: The influence of oestrogen and testosterone replacement on stroke risk has been examined, as well as mechanisms by which oestrogen may protect from post-stroke damage. However, whether testosterone levels in the early time period after haemorrhagic stroke influence long-term mortality has not previously been investigated. We examined whether these concentrations were predictive of risk of death. SETTING: University hospital. DESIGN: Prospective study...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28295702/effect-of-steroid-hormones-on-the-innate-immune-response-induced-by-staphylococcus-aureus-in-the-goat-mammary-gland
#10
K Kuwahara, Y Yoshimura, N Isobe
The objective of this study was to compare the dynamics of innate immune components after intramammary infusion of Staphylococcus aureus (SA) under conditions of high oestrogen and high progesterone in goats. In one group ("E-group"), controlled internal drug release (CIDR) devices were inserted intravaginally from days -11 to -4. Prostaglandin F2α was administered immediately after removal of the CIDR device at day -3, and then oestradiol benzoate (E) was injected intramuscularly once a day from days -2 to 3...
March 12, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28290259/synergistic-attenuation-of-ovariectomy-induced-bone-loss-by-combined-use-of-fish-oil-and-17%C3%AE-oestradiol
#11
Youri Jin, Myoungsook Lee, Yongsoon Park
Oestrogen and n-3 PUFA, especially EPA and DHA, have been reported to have beneficial effects on bone loss. Thus, the purpose of the present study was to investigate the synergistic bone-protective mechanism of combined treatments of EPA+DHA supplementation and oestrogen injection in ovariectomised rats. Rats were fed a modified American Institute of Nutrition-93G diet with 0 %, 1 % or 2 % n-3 PUFA (EPA+DHA) relative to the total energy intake for 12 weeks. Rats were surgically ovariectomised at week 8, and after a 1-week recovery period rats were injected with either 17β-oestradiol-3-benzoate (E2) or maize oil for the last 3 weeks...
March 14, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28276200/vasomotor-symptoms-due-to-natural-menopause-systematic-review-and-network-meta-analysis-nma-of-treatment-effects-from-the-nice-menopause-guideline
#12
Grammati Sarri, Hugo Pedder, Sofia Dias, Yelan Guo, Mary Ann Lumsden
BACKGROUND: Vasomotor symptoms (VMS) are the hallmarks of menopause, occurring in approximately 75% of postmenopausal women in the UK and are severe in 25%. OBJECTIVES: To identify which treatments are most clinically effective for the relief of VMS for non-hysterectomized women in natural menopause. SEARCH STRATEGY: English publications in MEDLINE, Embase and The Cochrane Library up to 13(th) January 2015 were searched. SELECTION CRITERIA: Randomized trials (RCTs) of treatments for women with a uterus for the outcomes of frequency of VMS (up to 26 weeks), vaginal bleeding and discontinuation...
March 9, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28257559/non-contraceptive-oestrogen-containing-preparations-for-controlling-symptoms-of-premenstrual-syndrome
#13
REVIEW
Bushra Naheed, Jan Herman Kuiper, Olalekan A Uthman, Fidelma O'Mahony, Patrick Michael Shaughn O'Brien
BACKGROUND: Premenstrual syndrome (PMS) is a psychological and somatic disorder of unknown aetiology, with symptoms typically including irritability, depression, mood swings, bloating, breast tenderness and sleep disturbances. About 3% to 10% of women who experience these symptoms may also meet criteria for premenstrual dysphoric disorder (PMDD). PMS symptoms recur during the luteal phase of the menstrual cycle and reduce by the end of menstruation. PMS results from ovulation and may be due to ovarian steroid interactions relating to neurotransmitter dysfunction...
March 3, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28244646/17%C3%AE-oestradiol-promotes-differentiation-of-human-embryonic-stem-cells-into-dopamine-neurons-via-cross-talk-between-insulin-like-growth-factors-1-and-oestrogen-receptor-%C3%AE
#14
Hong Li, Chenyue Ding, Zhi-Liang Ding, Mingfa Ling, Ting Wang, Wei Wang, Boxian Huang
Human embryonic stem cells (hESCs) can self-renew and differentiate into all cell lineages. E2 is known to exhibit positive effects on embryo development. Although the importance of E2 in many physiological processes has been reported, to date few researchers have investigated the effects of E2 on hESCs differentiation. We studied the effects of E2 on dopamine (DA) neuron induction of hESCs and its related signalling pathways using the three-stage protocol. In our study, 0.1 μM E2 were applied to hESCs-derived human embryoid bodies (hEBs) and effects of E2 on neural cells differentiation were investigated...
February 28, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28239742/the-role-of-the-sdf-1-cxcr7-axis-on-the-growth-and-invasion-ability-of-endometrial-cancer-cells
#15
Hong-Qin Gu, Zhen-Bo Zhang, Jia-Wen Zhang, Qian-Qian Wang, Xiao-Wei Xi, Yin-Yan He
PURPOSE: Stroma-derived factor-1 (SDF-1) and its receptor C-X-C chemokine receptor-4 (CXCR4) are involved in human endometrial carcinoma (EC) progression. CXCR7 is another important receptor of SDF-1 and has a higher affinity with SDF-1 compared with that of CXCR4. This paper aims to study the effects of the SDF-1/CXCR7 axis on the growth and invasion ability of EC cells. METHODS: CXCR7 expression was evaluated by quantitative RT-PCR, immunohistochemistry, immunocytochemistry and Western blotting in EC cell lines and 30 cases of primary EC tissue from patients...
February 27, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28228430/atypical-case-of-preterm-ovarian-hyperstimulation-syndrome
#16
Michelle A Durst, Brandy Wicklow, Michael Narvey
Preterm ovarian hyperstimulation syndrome is a rare syndrome in which preterm infant girls have hypogastric, upper leg and labial swelling accompanied by elevated serum oestradiol levels and ovarian follicular cysts on ultrasound. Our case is an infant born at 23 weeks gestational age who at 30 weeks postconceptional age (PCA) developed elevated 17-hydroxyprogesterone on her newborn screen with associated clitoromegaly and a ventral groove on the inferior aspect of the erectile tissue. An initial pelvic ultrasound at 32 weeks PCA demonstrated a normal appearing uterus, but the ovaries were not visualised...
February 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28197932/effect-of-gnrha-ovulation-trigger-dose-on-follicular-fluid-characteristics-and-granulosa-cell-gene-expression-profiles
#17
Thi Ngoc Lan Vuong, M T Ho, T Q Ha, M Brehm Jensen, C Yding Andersen, P Humaidan
PURPOSE: A recent dose-finding study showed no significant differences in number of mature oocytes, embryos and top-quality embryos when triptorelin doses of 0.2, 0.3 or 0.4 mg were used to trigger final oocyte maturation in oocyte donors co-treated with a gonadotropin-releasing hormone (GnRH) antagonist. This analysis investigated whether triptorelin dosing for triggering final oocyte maturation in oocyte donors induced differences in follicular fluid (FF) hormone levels and granulosa cell gene expression...
February 14, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28195504/postponement-of-puberty-in-queens-treated-with-deslorelin
#18
Marta Cecchetto, Paola Salata, Anna Baldan, Chiara Milani, Antonio Mollo, Christelle Fontaine, Hasan Sontas, Donatella Gelli, Giulia De Benedictis, Calogero Stelletta, Stefano Romagnoli
Objectives The purpose of this study was to assess efficacy of deslorelin, a gonadotropin-releasing hormone (GnRH) agonist marketed in Europe for the control of male dog reproduction, for the postponement of puberty in queens. Methods Nine prepubertal queens aged 3-9 months were selected for this study; their general and reproductive health was checked through clinical, haematological, vaginal cytology and hormonal tests. Following treatment with a 4.7 mg deslorelin implant each cat received a monthly clinical examination and blood was collected for hormonal assay every third month...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28187961/a-retrospective-analysis-of-ovarian-stimulation-with-letrozole-in-women-undergoing-artificial-insemination-by-donor
#19
X J Sun, L Jiang, L C Ji, R Nie, H Chen, L Jin, G J Zhu, K Qian
The aim of this retrospective study was to determine the clinical pregnancy rate in women undergoing letrozole ovarian stimulation and artificial insemination by donor (AID). Between 2012 and 2015, 130 natural cycles, 939 letrozole cycles and 130 letrozole plus gonadotrophin cycles were conducted. Letrozole cycles were divided into three groups according to LH concentration on the day of HCG administration (LH <10 mIU/ml and follicle size ≥18 cm; LH ≤10 to <20 mIU/ml; and LH ≥20 mIU/ml). Pregnancy rates were 17...
January 25, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28187384/study-on-the-removal-of-organic-micropollutants-from-aqueous-and-ethanol-solutions-by-hap-membranes-with-tunable-hydrophilicity-and-hydrophobicity
#20
Junyong He, Yulian Li, Xingguo Cai, Kai Chen, Hejing Zheng, Chengming Wang, Kaisheng Zhang, Dongyue Lin, Lingtao Kong, Jinhuai Liu
A biocompatible and uniquely defined hydroxyapatite (HAP) adsorption membrane with a sandwich structure was developed for the removal of organic micropollutants for the first time. Both the adsorption and membrane technique were used for the removal of organic micropollutants. The hydrophilicity and hydrophobicity of the HAP adsorbent and membrane were tunable by controlling the surface structure of HAP. The adsorption of organic micropollutants on the HAP adsorbent was studied in batch experiments. The adsorption process was fit with the Freundlich model, while the adsorption kinetics followed the pseudo-second-order model...
May 2017: Chemosphere
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