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association of vitamin d with gestational diabetes

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https://www.readbyqxmd.com/read/29235559/body-size-modifies-the-relationship-between-maternal-serum-25-hydroxyvitamin-d-concentrations-and-gestational-diabetes-in-high-risk-women
#1
Anita J Valkama, Jelena M Meinilä, Saila B Koivusalo, Jaana Lindström, Kristiina Rönö, Aila E Tiitinen, Beata Stach-Lempinen, Hannu J Kautiainen, Heli Viljakainen, Sture Andersson, Johan G Eriksson
Obesity increases the risk of low 25-hydroxyvitamin D (25(OH)D) concentrations and gestational diabetes (GDM). We explored whether the association between GDM and change in 25(OH)D concentrations measured in the first (7-18 wk) and second (20-27 wk) trimesters of pregnancy is dependent on maternal BMI. The study was a prospective study of 219 women with BMI of ≥30 kg/m2, a history of GDM, or both. The participants were stratified by first-trimester BMI: BMI of <25.0, 25.0-29.9, 30.0-34.9, and ≥35 kg/m2...
November 6, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29202779/correlates-of-poor-mental-health-in-early-pregnancy-in-obese-european-women
#2
Matteo C Sattler, Judith G M Jelsma, Annick Bogaerts, David Simmons, Gernot Desoye, Rosa Corcoy, Juan M Adelantado, Alexandra Kautzky-Willer, Jürgen Harreiter, Frans A van Assche, Roland Devlieger, Goele Jans, Sander Galjaard, David Hill, Peter Damm, Elisabeth R Mathiesen, Ewa Wender-Ozegowska, Agnieszka Zawiejska, Kinga Blumska, Annunziata Lapolla, Maria G Dalfrà, Alessandra Bertolotto, Fidelma Dunne, Dorte M Jensen, Lise Lotte T Andersen, Frank J Snoek, Mireille N M van Poppel
BACKGROUND: Depression during pregnancy is associated with higher maternal morbidity and mortality, and subsequent possible adverse effects on the cognitive, emotional and behavioral development of the child. The aim of the study was to identify maternal characteristics associated with poor mental health, in a group of overweight/obese pregnant women in nine European countries, and thus, to contribute to better recognition and intervention for maternal depression. METHODS: In this cross-sectional observational study, baseline data from early pregnancy (< 20 weeks) of the DALI (Vitamin D and Lifestyle Intervention for gestational diabetes mellitus prevention) study were analyzed...
December 4, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29169993/impact-of-vitamin-d-on-pregnancy-related-disorders-and-on-offspring-outcome
#3
REVIEW
Karoline von Websky, Ahmed Abdallah Hasan, Christoph Reichetzeder, Oleg Tsuprykov, Berthold Hocher
Observational studies from all over the world continue to find high prevalence rates of vitamin D insufficiency and deficiency in many populations, including pregnant women. Beyond its classical function as a regulator of calcium and phosphate metabolism, vitamin D elicits numerous effects in the human body. Current evidence highlights a vital role of vitamin D in mammalian gestation. During pregnancy, adaptations in maternal vitamin D metabolism lead to a physiologic increase of vitamin D levels, mainly because of an increased renal production, although other potential sources like the placenta are being discussed...
November 21, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29159790/vitamin-d-supplementation-in-pregnancy-a-survey-of-compliance-with-recommendations
#4
C M Windrim, D A Crosby, K Mitchell, C Brophy, R Mahony, M Higgins
BACKGROUND: Vitamin D deficiency in pregnancy has important maternal and fetal implications, with increased risk of developing gestational diabetes, preeclampsia, preterm birth and small for gestational age birthweight. It is recommended that every pregnant woman should take 5 μg (200 IU) of vitamin D per day during pregnancy and lactation. AIMS: This study aimed to determine the prevalence of women taking vitamin D supplementation and to identify the reasons for patients not taking supplementation within women attending an antenatal clinic in Dublin...
November 20, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29132457/-relationship-between-serum-25-oh-d-levels-at-birth-and-respiratory-distress-syndrome-in-preterm-infants
#5
Ren-Qiang Yu, Dao-Zhen Chen, Xiao-Qing Hao, Shi-Hong Jiang, Guang-Dong Fang, Qin Zhou
OBJECTIVE: To investigate the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels at birth and respiratory distress syndrome (RDS) in preterm infants. METHODS: This retrospective study recruited preterm infants with gestational age of below 34 weeks who were born between January 2014 and December 2016. These preterm infants were divided into two groups: RDS (n=72) and control (n=40). Clinical data of the two groups were collected, including gestational age, birth weight, gender, delivery mode, Apgar scores at 1 minute and 5 minutes, incidence of maternal gestational diabetes mellitus, and use of prenatal steroid hormone...
November 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29128634/vitamin-d-receptor-vdr-polymorphisms-are-associated-to-spontaneous-preterm-birth-and-maternal-aspects
#6
N R Javorski, C A D Lima, L V C Silva, S Crovella, J de Azêvedo Silva
Preterm birth (PTB) is featured by less than 37weeks of gestational age or fewer than 259days since the first day from the last menstrual period. Complications of PTB are the major cause of neonatal deaths, several factors are linked to PTB increased risk including immunological and genetics. Vitamin D plays an important role in immune response modulation and its action occurs through the vitamin D receptor (VDR), which recently has been described as overexpressed in human placenta during the pregnancy. Herein we assessed two single nucleotide polymorphisms (SNPs) FokI (rs2228570 A>G) and Cdx-2 (rs11568820 T>C), within VDR, using TaqMan fluorogenic probes, and differential susceptibility to SPTB...
November 8, 2017: Gene
https://www.readbyqxmd.com/read/29058058/maternal-early-pregnancy-plasma-concentration-of-25-hydroxyvitamin-d-and-risk-of-gestational-diabetes-mellitus
#7
Changen Xu, He-Hong Ma, Yao Wang
We examined whether 25-Hydroxyvitamin D [25(OH) D] concentrations, measured at the first prenatal visit, would be associated with risk of gestational diabetes mellitus (GDM). From July 2015 to June 2016, consecutive women who admitted to the two-obstetrics center in china were included. Relevant data were collected between 24 and 28 weeks of gestation, including fasting plasma glucose (FPG) and 25(OH) D concentrations at the first prenatal visit and the one-step GDM screened with 75-g oral glucose tolerance test (OGTT)...
October 22, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28989883/status-of-serum-vitamin-d-and-calcium-levels-in-women-of-reproductive-age-in-national-capital-territory-of-india
#8
Nighat Yaseen Sofi, Monika Jain, Umesh Kapil, Vuthaluru Seenu, Lakshmy Ramakrishnan, Chander Prakash Yadav, Ravindra Mohan Pandey
CONTEXT: In India, Vitamin D deficiency is a major public health problem, associated with lack of sunlight exposure in spite of abundant sunshine usually accompanied by reduced dietary intake. In women of reproductive age, Vitamin D deficiency in pregnancy has been associated with an increased risk of gestational diabetes mellitus, preeclampsia, maternal and perinatal morbidity and mortality. AIMS: The aim of the present cross-sectional study was to evaluate the levels of serum Vitamin D 25(OH) D and calcium in women of reproductive age from India...
September 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28976079/pre-pregnancy-habitual-intake-of-vitamin-d-from-diet-and-supplements-in-relation-to-risk-of-gestational-diabetes-mellitus-a-prospective-cohort-study
#9
Wei Bao, Yiqing Song, Kimberly A Bertrand, Deirdre K Tobias, Sjurdur F Olsen, Jorge E Chavarro, James L Mills, Frank B Hu, Cuilin Zhang
BACKGROUND: Vitamin D may play a pivotal role in regulating insulin secretion and insulin sensitivity. However, the impact of vitamin D intake either from diet or from supplements on the development of gestational diabetes mellitus (GDM) remains unknown. We prospectively examined the association of pre-pregnancy habitual intake of vitamin D from diet and supplements with risk of incident GDM in a well-established cohort. METHODS: We included 21,356 singleton pregnancies from 15,225 women in the Nurses' Health Study II cohort...
October 4, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28901336/vitamin-d-and-probiotics-supplement-use-in-young-children-with-genetic-risk-for-type-1-diabetes
#10
J Yang, R N Tamura, U M Uusitalo, C A Aronsson, K Silvis, A Riikonen, N Frank, G Joslowski, C Winkler, J M Norris, S M Virtanen
BACKGROUND/OBJECTIVES: Vitamin D and probiotics are nutrients of interest in the context of type 1 diabetes (T1D). We assessed the prevalence of and factors associated with vitamin D and probiotic supplementations among young children with genetic risk of T1D. SUBJECTS/METHODS: Use of supplements during the first 2 years of life was collected prospectively from 8674 children in The Environmental Determinants of Diabetes in the Young (TEDDY) study. RESULTS: Single and/or multivitamin/mineral (MVM) supplements were reported by 81% of the children...
September 13, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28882133/is-a-motivational-interviewing-based-lifestyle-intervention-for-obese-pregnant-women-across-europe-implemented-as-planned-process-evaluation-of-the-dali-study
#11
Judith G M Jelsma, David Simmons, Nina Gobat, Stephen Rollnick, Kinga Blumska, Goele Jans, Sander Galjaard, Gernot Desoye, Rosa Corcoy, Fabiola Juarez, Alexandra Kautzky-Willer, Jürgen Harreiter, Andre van Assche, Roland Devlieger, Dirk Timmerman, David Hill, Peter Damm, Elisabeth R Mathiesen, Ewa Wender-Ożegowska, Agnieszka Zawiejska, Annunziata Lapolla, Maria G Dalfrà, Stefano Del Prato, Alessandra Bertolotto, Fidelma Dunne, Dorte M Jensen, Liselotte Andersen, Frank J Snoek, Mireille N M van Poppel
BACKGROUND: Process evaluation is an essential part of designing and assessing complex interventions. The vitamin D and lifestyle intervention study (DALI) study is testing different strategies to prevent development of gestational diabetes mellitus among European obese pregnant women with a body mass index ≥29 kg/m(2). The intervention includes guidance on physical activity and/or healthy eating by a lifestyle coach trained in motivational interviewing (MI). The aim of this study was to assess the process elements: reach, dose delivered, fidelity and satisfaction and to investigate whether these process elements were associated with changes in gestational weight gain (GWG)...
September 7, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28741856/relationship-between-vitamin-d-and-gestational-diabetes-in-overweight-or-obese-pregnant-women-may-be-mediated-by-adiponectin
#12
Aya Mousa, Sally K Abell, Soulmaz Shorakae, Cheryce L Harrison, Negar Naderpoor, Danielle Hiam, Alba Moreno-Asso, Nigel K Stepto, Helena J Teede, Barbora de Courten
SCOPE: Maternal vitamin D deficiency has been implicated in adverse pregnancy outcomes. However, the association between vitamin D and inflammation, particularly adipokines, remains unexplored in pregnancy. METHODS AND RESULTS: In 102 overweight or obese pregnant women at high-risk of gestational diabetes mellitus (GDM), we investigated relationships between maternal 25-hydroxyvitamin D (25(OH)D) concentrations at 12-15 wk gestation (baseline) and serum lipids, inflammatory markers, novel adipokines (omentin-1, visfatin, high molecular weight (HMW) adiponectin), and subsequent pregnancy outcomes (GDM, preeclampsia, preterm birth [PTB])...
July 25, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28702810/epidemiology-of-gestational-diabetes-mellitus-according-to-iadpsg-who-2013-criteria-among-obese-pregnant-women-in-europe
#13
Aoife M Egan, Akke Vellinga, Jürgen Harreiter, David Simmons, Gernot Desoye, Rosa Corcoy, Juan M Adelantado, Roland Devlieger, Andre Van Assche, Sander Galjaard, Peter Damm, Elisabeth R Mathiesen, Dorte M Jensen, Liselotte Andersen, Annuziata Lapolla, Maria G Dalfrà, Alessandra Bertolotto, Urszula Mantaj, Ewa Wender-Ozegowska, Agnieszka Zawiejska, David Hill, Judith G M Jelsma, Frank J Snoek, Christof Worda, Dagmar Bancher-Todesca, Mireille N M van Poppel, Alexandra Kautzky-Willer, Fidelma P Dunne
AIMS/HYPOTHESIS: Accurate prevalence estimates for gestational diabetes mellitus (GDM) among pregnant women in Europe are lacking owing to the use of a multitude of diagnostic criteria and screening strategies in both high-risk women and the general pregnant population. Our aims were to report important risk factors for GDM development and calculate the prevalence of GDM in a cohort of women with BMI ≥29 kg/m(2) across 11 centres in Europe using the International Association of the Diabetes and Pregnancy Study Groups (IADPSG)/WHO 2013 diagnostic criteria...
October 2017: Diabetologia
https://www.readbyqxmd.com/read/28674684/effect-of-fetal-sex-on-maternal-and-obstetric-outcomes
#14
REVIEW
Mohammed Al-Qaraghouli, Yu Ming Victor Fang
Fetal sex plays an important role in modifying the course and complications related to pregnancy and may also have an impact on maternal health and well-being both during and after pregnancy. The goal of this article is to review and summarize the findings from published research on physiologic and pathologic changes that may be affected by fetal sex and the effect of these changes on the maternal and obstetrical outcomes. This will help create awareness that fetal sex is not just a random chance event but an interactive process between the mother, the placenta, and the fetus...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28625206/organic-food-consumption-during-pregnancy-and-its-association-with-health-related-characteristics-the-koala-birth-cohort-study
#15
Ana Paula Simões-Wüst, Carolina Moltó-Puigmartí, Eugene Hjm Jansen, Martien Cjm van Dongen, Pieter C Dagnelie, Carel Thijs
OBJECTIVE: To investigate the associations of organic food consumption with maternal pre-pregnancy BMI, hypertension and diabetes in pregnancy, and several blood biomarkers of pregnant women. DESIGN: Prospective cohort study. SETTING: Pregnant women were recruited at midwives' practices and through channels related to consumption of food from organic origin. SUBJECTS: Pregnant women who filled in FFQ and donated a blood sample (n 1339)...
August 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28593917/vitamin-d-deficiency-in-pregnancy-at-term-risk-factors-and-pregnancy-outcomes
#16
Chui Ling Lee, Beng Kwang Ng, Loo Ling Wu, Fook Choe Cheah, Hanita Othman, Nor Azlin Mohamed Ismail
Background Vitamin D deficiency during pregnancy is a worldwide epidemic. The aim of this study was to determine the prevalence of vitamin D deficiency, its predictive factors and the association with pregnancy outcomes. Materials and methods This was a prospective observational study in a tertiary teaching hospital over 2-years' duration from August 2013 to August 2015. A total of 680 women who completed 37 weeks of pregnancy were recruited. Results Five hundred and seventy-five patients were enrolled in the final analysis for pregnancy outcomes (response rate of 84...
May 26, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28590451/environmental-factors-associated-with-type-1-diabetes-development-a-case-control-study-in-egypt
#17
Nabil J Awadalla, Amal A Hegazy, Manal Abd El-Salam, Marwa Elhady
Uncertainty still exists regarding the role of some environmental risk in the development of type 1 diabetes mellitus (T1DM) both globally and in Egypt. The objective here was to explore the potential environmental risk factors associated with the development of T1DM among children in Egypt. A case-controlled study of 204 T1DM children and an equal number of age and sex-matched controls was conducted in Assiut, Egypt. Data regarding the parental, gestational, neonatal, and childhood possible risk factors for T1DM were evaluated...
June 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28555324/low-maternal-circulating-levels-of-vitamin-d-as-potential-determinant-in-the-development-of-gestational-diabetes-mellitus
#18
REVIEW
S Triunfo, A Lanzone, P G Lindqvist
Gestational diabetes mellitus (GDM), defined as any glucose intolerance with the onset or first recognition during pregnancy, is characterized by rising incidence, fostered by the worldwide increase of pathological nutritional status from young age. Clinical research has intended to identify potential risk factors, suggested improvements in screening strategies, and recommended the combination between promotion of an appropriate lifestyle before and during pregnancy and selected therapeutic approaches. Preventing pathological hyperglycemia could have several benefits, ranging from clinical side (reduction in the risk of adverse perinatal and long-term sequelae) to financial side (cost reduction to healthcare systems)...
October 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28276579/glucose-homeostasis-beta-cell-function-and-insulin-resistance-in-relation-to-vitamin-d-status-after-gestational-diabetes-mellitus
#19
Nael Shaat, Claes Ignell, Anastasia Katsarou, Kerstin Berntorp
INTRODUCTION: We wanted to determine vitamin D status after gestational diabetes mellitus (GDM) and to evaluate whether levels of 25-hydroxyvitamin D3 (25OHD3 ) are associated with beta cell function, insulin resistance or a diagnosis of diabetes after GDM. MATERIAL AND METHODS: Glucose homeostasis was assessed during a 75-g oral glucose tolerance test one to two years after delivery in 376 women with previous GDM (287 European and 78 non-European, including 33 Arab and 35 Asian women)...
July 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28244707/serum-25-hydroxyvitamin-d-in-pregnant-women-during-preterm-labor
#20
Nalina Bhupornvivat, Vorapong Phupong
BACKGROUND AND OBJECTIVES: Pregnancy complications hypothesized to be related to vitamin D include preeclampsia, gestational diabetes, low birth weight, preterm delivery, Cesarean section and infectious disease. There have been a few studies which have demonstrated maternal serum vitamin D to be associated with preterm labor. The objective was to evaluate the serum vitamin D concentrations in Thai pregnant women with and without preterm labor and to find the prevalence of vitamin D deficiency and insufficiency in both groups...
March 2017: Asia Pacific Journal of Clinical Nutrition
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