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https://www.readbyqxmd.com/read/29690935/combination-therapy-involving-radiofrequency-ablation-and-targeted-chemotherapy-with-bevacizumab-plus-paclitaxel-and-cisplatin-in-a-rabbit-vx2-lung-tumor-model
#1
Ai Ueki, Tomohisa Okuma, Shinichi Hamamoto, Ken Kageyama, Kazuki Murai, Yukio Miki
OBJECTIVE: Radiofrequency ablation (RFA) is less effective for large tumors > 3 cm in diameter. Various studies of combination therapy using RFA and other treatments have been conducted to improve the results of RFA treatment of lung tumors, survival was extended in a tumor model when RFA was followed by concomitant use of systemic chemotherapy. Bevacizumab (BCM) is a one of molecular target drugs. Numerous clinical trials and reports have shown BCM's effect when used in combination with cisplatin (CDDP) in lung tumor...
April 24, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29689761/rf-ablation-thermal-simulation-model-parameter-sensitivity-analysis
#2
Xiaoru Wang, Hongjian Gao, Shuicai Wu, Yanping Bai, Zhuhuang Zhou
OBJECTIVE: The aim of the research is to obtain the relative influences of some critical electro-thermal parameters on the ablation temperature and lesion volume during temperature-controlled radiofrequency ablation (RFA) of liver tumor by parameter sensitivity analysis. METHODS: The finite element method (FEM) has been used to establish the simulation model of RFA temperature field, and the sensitivity of the tissue parameters has been analyzed. The effects of six parameters have been taken into account, including the thermal specific capacity (Cp), the thermal conductivity (k), the electrical conductivity (Sigma), the density (rho), the dielectric constant (Epsilon) and the resistance (R)...
April 10, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29689573/systematic-review-and-meta-analysis-of-the-effectiveness-of-radiofrequency-ablation-in-low-grade-dysplastic-barrett-s-esophagus
#3
Gargi Pandey, Mubashir Mulla, Wyn G Lewis, Antonio Foliaki, David S Y Chan
BACKGROUND:  Barrett's esophagus (BE) is a premalignant condition characterized by replacement of the esophageal lining with metastatic columnar epithelium, and its management when complicated by low grade dysplasia (LGD) is controversial. This systematic review and meta-analysis aimed to determine the efficacy of radiofrequency ablation (RFA) in patients with LGD. METHODS:  MEDLINE, EMBASE, and Web of Science were searched for studies including patients with BE-associated LGD receiving RFA (January 1990 to May 2017)...
April 24, 2018: Endoscopy
https://www.readbyqxmd.com/read/29688199/-radiofrequency-ablation-in-comprehensive-surgical-treatment-of-patients-with-varicose-veins-of-lower-limbs
#4
M D Dibirov, A I Shimanko, R U Gadzhimuradov, A S Volkov, D S Tiurin, A Kh Magdiev
Analysed herein are the results of using radiofrequency ablation (RFA) in comprehensive surgical treatment of patients presenting with varicose veins of the lower extremities. The study included a series of ninety-eight 28-to-60-year-old patients (with a total of 105 operations performed) suffering from varicose veins of the lower limbs. Of these, there were 10 men (10.3%) and 88 women (89.7%). Venous disease of clinical class C2 according to the CEAP classification was diagnosed in 80 patients, that of class C3 in 17, and that of class C4a in 1 patient...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29688153/medium-or-large-hepatocellular-carcinoma-sorafenib-combined-with-transarterial-chemoembolization-and-radiofrequency-ablation
#5
Kangshun Zhu, Jingjun Huang, Lisha Lai, Wensou Huang, Mingyue Cai, Jingwen Zhou, Yongjian Guo, Junwei Chen
Purpose To determine the safety and efficacy of sorafenib combined with transarterial chemoembolization (TACE) and radiofrequency ablation (RFA) (hereafter, S-TACE-RFA) in patients with medium or large (range, 3.1-7.0 cm in diameter) hepatocellular carcinoma (HCC). Materials and Methods This retrospective study evaluated the medical records of consecutive patients with medium or large HCC who underwent S-TACE-RFA or combined TACE and RFA (hereafter, TACE-RFA) from January 2010 to December 2014. Sorafenib was started 3-5 days after TACE, and RFA was performed 1-2 weeks after TACE...
April 24, 2018: Radiology
https://www.readbyqxmd.com/read/29687416/mrecist-criteria-to-assess-recurrent-thyroid-carcinoma-treatment-response-after-radiofrequency-ablation-a-prospective-study
#6
S Mazzeo, R Cervelli, R Elisei, G Tarantini, C Cappelli, E Molinaro, D Galleri, L De Napoli, C Comite, R Cioni, P Vitti, D Caramella
PURPOSE: Surgical removal is recommended for recurrent thyroid carcinomas (RTCs) unable to uptake radioiodine and/or not responsive to chemotherapy. However, repeated neck dissection is difficult for surgeons. Thus, radiofrequency ablation (RFA) was proposed for RTCs. The aim of this prospective study is to assess RTC treatment response after RFA, according to well-established criteria. METHODS: Sixteen lesions in 13 patients were treated by RFA. All patients refused/were excluded from repeated surgery or other conventional therapy...
April 23, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29685588/effect-of-microbubble-enhanced-ultrasound-on-radiofrequency-ablation-of-rabbit-liver
#7
Zhong Chen, Hongzhi Zhao, Xueyan Qiao, Cuo Yi, Shunji Gao, Wenhong Gao, Zheng Liu
Microbubble-enhanced ultrasound (MEUS) can non-invasively disrupt and block liver blood perfusion. It may potentially overcome the heat sink effect during a thermal ablation and consequently enhance radiofrequency ablation (RFA) of the liver. We propose a new strategy combining RFA with MEUS. For ultrasound treatment, an 831-kHz air-backed focused transducer directed 400-cycle bursts at 4.3 MPa to the liver at a 9-Hz rate. The treatment was nucleated by a lipids microbubble forming MEUS. Eighteen surgically exposed rabbit livers were treated using MEUS combined with RFA; the other 32 livers were treated using MEUS (n = 14) or RFA (n = 18) alone and served as the controls...
April 20, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29683893/resonance-frequency-analysis-of-dental-implants-with-2-types-of-surface-treatment-submitted-to-immediate-loading-a-prospective-clinical-study
#8
Rafael Amorim Cavalcanti Siqueira, Ivete Aparecida de Mattias Sartori, Paulo Gustavo Freitas Santos, Márcio John Thiesen, Mylene Cassia Gonçalves, Flávia Noemy Gasparini Kiatake Fontão
BACKGROUND: Characteristics of the implant surface may benefit osseointegration, and the knowledge of this process in diverse clinical situations may play a role in implant dentistry practice. PURPOSE: The aim of the present study was to compare the stability of dental implants with different types of surface treatment. MATERIALS AND METHODS: Fifty-five implants were placed in the mandibles of 11 fully edentulous patients. Group 1 (G1) consisted of 27 implants with a hydrophilic surface...
April 20, 2018: Implant Dentistry
https://www.readbyqxmd.com/read/29683022/transarterial-chemoembolization-plus-multi-imaging-guided-radiofrequency-ablation-for-elimination-of-hepatocellular-carcinoma-nodules-measuring-3-1-to-5-0-cm-a-single-center-study
#9
Wang Haochen, Wang Jian, Song Li, Lv Tianshi, Tong Xiaoqiang, Zou Yinghua
Objective This study was performed to determine whether transarterial chemoembolization (TACE) plus multi-imaging-guided radiofrequency ablation (MIG-RFA) can completely eliminate 3.1- to 5.0-cm hepatocellular carcinoma (HCC) nodules and identify factors that may influence the complete elimination rate (CER) of this therapy. Methods Patients who underwent TACE+MIG-RFA for initial treatment of HCC from January 2008 to January 2016 were retrospectively reviewed. In total, 162 patients with 216 HCC nodules (3...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29678784/feasibility-safety-and-efficacy-of-a-novel-pre-shaped-nitinol-esophageal-deviator-to-successfully-deflect-the-esophagus-and-ablate-left-atrium-without-esophageal-temperature-rise-during-atrial-fibrillation-ablation-the-deflect-gut-study
#10
Valay Parikh, Vijay Swarup, Jacob Hantla, Venkat Vuddanda, Tawseef Dar, Bharath Yarlagadda, Luigi Di Biase, Amin Al-Ahmad, Andrea Natale, Dhanunjaya Lakkireddy
BACKGROUND: Esophageal thermal injury is a feared complication of radiofrequency ablation (RFA) for atrial fibrillation (AF). Rise in luminal esophageal temperature (LET) limits the ability to deliver RF energy on posterior wall of LA. OBJECTIVE: The aim of this registry was to evaluate feasibility, safety and efficacy of a mechanical esophageal deviation (ED) tool during AF ablation. METHODS: We evaluated 687 patients who underwent RFA for AF...
April 17, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29678685/success-rate-and-factors-predictive-of-redo-radiofrequency-ablation-of-perforator-veins
#11
Afsha Aurshina, Enrico Ascher, Lauren Mount, Amrit Hingorani, Natalie Marks, Anil Hingorani
OBJECTIVE: Radiofrequency ablation (RFA) is increasingly being employed for treatment of perforator vein insufficiency and venous ulcer healing. Previous studies have shown a closure rate of 60% to 80% in incompetent perforator veins (IPVs) with RFA. The purpose of the study was to determine the utility of a redo RFA for symptomatic recanalized perforators and to predict factors associated with recanalization. METHODS: A retrospective analysis of 642 procedures in 256 patients with venous insufficiency due to IPVs from 2009 to 2015 was conducted...
April 17, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29675904/risk-factors-for-fetal-death-after-radiofrequency-ablation-for-complicated-monochorionic-twin-pregnancies
#12
Luming Sun, Gang Zou, Yingjun Yang, Fenhe Zhou, Duan Tao
OBJECTIVE: Radiofrequency ablation (RFA) is a management alternative for complicated monochorionic twin pregnancies. The purpose of this study is to evaluate risk factors for fetal death after RFA. METHODS: An observational study was performed to document the perinatal outcomes of all cases undergoing fetal reduction using RFA from 2010 to 2016 at the Shanghai First Maternity and Infant Hospital. A multiple regression model was built to identify predictors of the death of the remaining fetus after RFA...
April 19, 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29675772/phase-i-ii-study-of-radiofrequency-ablation-for-painful-bone-metastases-japan-interventional-radiology-in-oncology-study-group-0208
#13
Noboru Tanigawa, Yasuaki Arai, Koichiro Yamakado, Takeshi Aramaki, Yoshitaka Inaba, Susumu Kanazawa, Osamu Matsui, Masaya Miyazaki, Yoshihisa Kodama, Hiroshi Anai, Akihiro Hamanaka
PURPOSE: A prospective multicenter phase I/II trial was performed to evaluate the clinical safety and efficacy of radiofrequency ablation (RFA) for metastatic bone tumors. MATERIALS AND METHODS: Thirty-three patients (27 men, 6 women, mean age 61 years) with metastatic bone tumors were enrolled. In phase I, nine patients were enrolled, and the safety of RFA was evaluated. In phase II, 23 patients were included, and an intent-to-treat analysis was performed. The primary endpoint was to evaluate the treatment's safety...
April 12, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29671157/natural-history-of-the-post-ablation-esophagus
#14
REVIEW
Craig C Reed, Nicholas J Shaheen
Endoscopic ablative therapy including radiofrequency ablation (RFA) represents the preferred management strategy for dysplastic Barrett's esophagus (BE) and appears to diminish the risk of developing esophageal adenocarcinoma (EAC). Limited data describe the natural history of the post-ablation esophagus. Recent findings demonstrate that recurrent intestinal metaplasia (IM) following RFA is relatively frequent. However, dysplastic BE and EAC subsequent to the complete eradication of intestinal metaplasia (CEIM) are uncommon...
April 18, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29670382/clinical-outcomes-and-health-care-utilization-pre-and-post-laparoscopic-radiofrequency-ablation-of-symptomatic-fibroids-and-laparoscopic-myomectomy-a-randomized-trial-of-uterine-sparing-techniques-trust-in-canada
#15
Darrien D Rattray, Laura Weins, Lexy C Regush, James M Bowen, Daria O'Reilly, John A Thiel
Objective: The objective of this study was to compare laparoscopic ultrasound-guided radiofrequency ablation of fibroids (Lap-RFA) and laparoscopic myomectomy in terms of 1) health care utilization and 2) serious complication rates. The secondary objectives were comparison of subject responses to validated symptom and quality-of-life questionnaires. We hypothesized that Lap-RFA health care utilization and clinical outcomes would not be worse than those of laparoscopic myomectomy in the aggregate...
2018: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29666906/radiofrequency-and-microwave-ablation-compared-to-systemic-chemotherapy-and-to-partial-hepatectomy-in-the-treatment-of-colorectal-liver-metastases-a-systematic-review-and-meta-analysis
#16
Martijn R Meijerink, Robbert S Puijk, Aukje A J M van Tilborg, Kirsten Holdt Henningsen, Llenalia Garcia Fernandez, Mattias Neyt, Juanita Heymans, Jacqueline S Frankema, Koert P de Jong, Dick J Richel, Warner Prevoo, Joan Vlayen
PURPOSE: To assess safety and outcome of radiofrequency ablation (RFA) and microwave ablation (MWA) as compared to systemic chemotherapy and partial hepatectomy (PH) in the treatment of colorectal liver metastases (CRLM). METHODS: MEDLINE, Embase and the Cochrane Library were searched. Randomized trials and comparative observational studies with multivariate analysis and/or matching were included. Guidelines from National Guideline Clearinghouse and Guidelines International Network were assessed using the AGREE II instrument...
April 17, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29665588/current-technique-and-application-of-percutaneous-cryotherapy
#17
Andreas H Mahnken, Alexander Marc König, Jens Holger Figiel
PURPOSE:  Local ablative therapies have become an established treatment option in interventional oncology. Radiofrequency ablation (RFA) and microwave ablation (MWA) are a standard of care in the treatment of hepatocellular carcinoma (HCC). Currently, there is an increasing interest in cryotherapy, one of the oldest ablation techniques. It has some unique characteristics with regard to technology and mechanism of action. MATERIALS AND METHODS:  A systematic literature search using the terms cryotherapy, cryosurgery and cryoablation was performed...
April 17, 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29662834/liver-stiffness-measured-by-two-dimensional-shear-wave-elastography-prognostic-value-after-radiofrequency-ablation-for-hepatocellular-carcinoma
#18
Dong Ho Lee, Jeong Min Lee, Jung-Hwan Yoon, Yoon Jun Kim, Jeong-Hoon Lee, Su Jong Yu, Joon Koo Han
Purpose: To evaluate the prognostic value of liver stiffness (LS) measured using two-dimensional (2D) shear-wave elastography (SWE) in patients with hepatocellular carcinoma (HCC) treated by radiofrequency ablation (RFA). Methods: The Institutional Review Board approved this retrospective study and informed consent was obtained from all patients. A total of 134 patients with up to 3 HCCs ≤5 cm who had undergone pre-procedural 2D-SWE prior to RFA treatment between January 2012 and December 2013 were enrolled...
March 2018: Liver Cancer
https://www.readbyqxmd.com/read/29660322/efficacy-and-safety-of-endobiliary-radiofrequency-ablation-for-the-eradication-of-residual-neoplasia-after-endoscopic-papillectomy-a-multicenter-prospective-study
#19
Marine Camus, Bertrand Napoléon, Ariane Vienne, Marc Le Rhun, Sarah Leblanc, Maximilien Barret, Stanislas Chaussade, Françoise Robin, Nadira Kaddour, Frederic Prat
BACKGROUND: and study aims: Endobiliary dysplasia may persist after endoscopic papillectomy. Intraductal radiofrequency ablation (ID-RFA) is a potential alternative to complementary surgery. The aim of the study was to evaluate the efficacy and safety of ID-RFA for the treatment of adenomatous intraductal residue after endoscopic papillectomy. PATIENTS AND METHODS: A prospective open-label multicenter study included patients with histologically proven endobiliary adenoma remnant (ductal extent <20 mm), after endoscopic papillectomy for ampullary tumor...
April 13, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29655833/development-of-evidence-based-surveillance-intervals-following-radiofrequency-ablation-of-barrett-s-esophagus
#20
Cary C Cotton, Rehan Haidry, Aaron P Thrift, Laurence Lovat, Nicholas J Shaheen
BACKGROUND AND AIMS: Barrett's esophagus (BE) recurs in 25% or more of patients treated successfully with radiofrequency ablation (RFA), so surveillance endoscopy is recommended after complete eradication of intestinal metaplasia (CEIM). The frequency of surveillance is informed only by expert opinion. We aimed to model the incidence of neoplastic recurrence, validate the model in an independent cohort, and propose evidence-based surveillance intervals. METHODS: We collected data from the United States Radiofrequency Ablation Registry (US RFA, 2004-2013) and the United Kingdom National Halo Registry (UK NHR, 2007-2015) to build and validate models to predict the incidence of neoplasia recurrence following initially successful RFA...
April 12, 2018: Gastroenterology
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