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https://www.readbyqxmd.com/read/29040990/non-hypervascular-hypointense-hepatic-nodules-during-the-hepatobiliary-phase-of-gadolinium-ethoxybenzyl-diethylenetriamine-pentaacetic-acid-enhanced-mri-as-a-risk-factor-of-intrahepatic-distant-recurrence-after-radiofrequency-ablation-of-hepatocellular-carcinoma
#1
Takayuki Iwamoto, Yasuharu Imai, Takumi Igura, Sachiyo Kogita, Yoshiyuki Sawai, Kazuto Fukuda, Yoshitaka Yamaguchi, Yasushi Matsumoto, Masanori Nakahara, Osakuni Morimoto, Hiroshi Ohashi, Norihiko Fujita, Masatoshi Kudo, Tetsuo Takehara
BACKGROUND: Non-hypervascular hypointense hepatic nodules during the hepatobiliary phase of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MRI have been reported to be associated with intrahepatic distant recurrence (IDR) after hepatectomy or radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). IDR is categorized into hypervascular transformation of non-hypervascular hypointense hepatic nodules and new intrahepatic recurrence. The aim of this study was to evaluate the relationship between non-hypervascular hypointense hepatic nodules on Gd-EOB-DTPA-enhanced MRI and IDR after RFA, focusing on new intrahepatic recurrence...
2017: Digestive Diseases
https://www.readbyqxmd.com/read/29037917/immunomodulation-after-radiofrequency-ablation-of-locally-advanced-pancreatic-cancer-by-monitoring-the-immune-response-in-10-patients
#2
Alessandro Giardino, Giulio Innamorati, Stefano Ugel, Omar Perbellini, Roberto Girelli, Isabella Frigerio, Paolo Regi, Filippo Scopelliti, Giovanni Butturini, Salvatore Paiella, Matilde Bacchion, Claudio Bassi
OBJECTIVE/BACKGROUND: RFA of pancreatic cancer has been demonstrated to be feasible and safe with a positive impact on survival. The aim was to investigate whether an immune reaction is activated after locally advanced pancreatic cancer (LAPC) ablation. METHODS: Peripheral Blood samples were obtained preoperatively and on post-operative days 3-30. Evaluated parameters were: cells [CD4(+), CD8(+) and activated subsets, T-Reg, Monocytes, myeloid and plasmocytoid Dendritic cells (mDC and pDC)] and cytokines [Interleukin (IL)-6, Stromal-cells derived factor (SDF)-1, IL-1β, Tumour-Necrosis Factor (TNF)-α, Interferon (IFN)-γ, Vascular Endothelial Growth Factor (VEGF), chemokine (C-C motif) ligand 5 (CCL-5), Transforming-Growth Factor (TGF)-β]...
September 27, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/29037353/shortened-protocol-for-radiofrequency-ablation-of-perforator%C3%A2-veins
#3
Afsha Aurshina, Anil Hingorani, Sheila Blumberg, Ahmad Alsheekh, Natalie Marks, Amrit Hingorani, Eleanor Iadagarova, Enrico Ascher
BACKGROUND: Routine radiofrequency ablation (RFA) of an incompetent perforator vein (IPV) using the standard treatment protocol at 85°C has a treatment time of 6 minutes. To make treatment time more efficient, we sought to determine the effect of a shortened protocol for radiofrequency stylet (RFS) ablation by comparing the early success using three different temperatures: 85°C, 90°C, and 95°C. METHODS: A retrospective study examined 642 procedures of IPV closures in 255 patients with varying degrees of venous insufficiency treated with RFA from 2009 to 2015...
November 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29037350/prospective-study-of-safety-and-effectiveness-in-the-use-of-radiofrequency-ablation-for-incompetent-great-saphenous-vein-%C3%A2-12%C3%A2-mm
#4
Maday Cabrero Fernandez, Isaac Martinez Lopez, Manuela Maria Hernandez Mateo, Pablo Marques de Marino, Iñaki Cernuda Artero, Francisco Javier Serrano Hernando
OBJECTIVE: The objective of this study was to assess the outcomes of radiofrequency ablation (RFA) in incompetent great saphenous vein (GSV) according to its diameter. METHODS: This was a prospective single-center study including all patients treated with RFA from September 2014 to December 2015. The sample was divided according to the maximum GSV diameter measured on duplex ultrasound scan (A, <12 mm; B, ≥12 mm). Second-generation catheters (ClosureFast; Covidien, Mansfield, Mass) and tumescent anesthesia were used...
November 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29036312/safety-and-efficacy-of-cryoablation-vs-radiofrequency-ablation-of-septal-accessory-pathways-systematic-review-of-the-literature-and-meta-analyses
#5
Loreto Bravo, Felipe Atienza, Gabriel Eidelman, Pablo Ávila, Mauricio Pelliza, Evaristo Castellanos, Gerard Loughlin, Tomás Datino, Esteban G Torrecilla, Jesús Almendral, Pedro Luis Sánchez, Ángel Arenal, Nieves Martínez-Alzamora, Francisco Fernández-Avilés
Aims: Radiofrequency ablation (RFA) of septal accessory pathways (APs) is associated with a significant rate of first procedure failures and complications. Cryoablation is an alternative energy source but there are no studies comparing both ablation techniques. We aimed to systematically review the literature and compare the efficacy and safety of cryoablation vs. RFA of septal APs. Methods and results: We conducted two separate meta-analysis of cryoablation and RFA of septal APs and calculated the global estimates of the efficacy and safety...
October 3, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29034691/combined-transarterial-chemoembolization-and-radiofrequency-ablation-for-small-treatment-na%C3%A3-ve-hepatocellular-carcinoma-infeasible-for-ultrasound-guided-radiofrequency-ablation-long-term-outcomes
#6
Dongho Hyun, Sung Ki Cho, Sung Wook Shin, Kwang Bo Park, Sang Yub Lee, Hong Suk Park, Young Soo Do
Background Ultrasound (US)-guided radiofrequency ablation (RFA) for small hepatocellular carcinoma (HCC) is often infeasible due to unfavorable location and poor conspicuity. Those small HCCs can be treated with combined transarterial chemoembolization (TACE) and RFA. Purpose To evaluate long-term outcomes of combined TACE and RFA for small treatment-naïve HCC infeasible for US-guided RFA. Material and Methods Between February 2009 and January 2014, 69 patients with small (≤3 cm) HCC infeasible for US-guided RFA received TACE and subsequent RFA in one session as a first-line treatment...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29033573/ten-year-outcome-of-intraoperative-treatment-of-atrial-fibrillation-using-radiofrequency-ablation
#7
Nour Boulad, Nicolas W Shammas, Gerald Early, Shauna Roberts, Gail A Shammas, Yuhning Linda Hu, Holly Park, Michael Jerin
BACKGROUND: Intraoperative radiofrequency ablation (RFA) has been advocated to treat atrial fibrillation (AF). This report examines the long-term effects of intraoperative RFA in the prevention of recurrence of AF when used as an adjunctive treatment in patients undergoing cardiac procedures for primary indications unrelated to their arrhythmia. METHODS: The study reviewed the records of patients from a tertiary medical center which had 2 cardiac surgeons performing an intraoperative adjunctive RFA procedure...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29031662/percutaneous-treatment-of-hepatocellular-carcinoma-state-of-the-art-and-innovations
#8
REVIEW
Jean-Charles Nault, Olivier Sutter, Pierre Nahon, Nathalie Ganne-Carrié, Olivier Séror
Percutaneous treatment of hepatocellular carcinoma (HCC) encompasses a vast range of techniques, including monopolar radiofrequency ablation (RFA), multibipolar RFA, microwave ablation, cryoablation and irreversible electroporation. RFA is considered to be one of the main curative treatments for HCC of less than 5 cm developing on cirrhosis, together with surgical resection and liver transplantation. However, controversies exist concerning the respective roles of ablation and liver resection for HCC of less than 3 to 5 cm on cirrhosis...
October 12, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/29029986/radiofrequency-ablation-for-colorectal-cancer-liver-metastases-initially-greater-than-25%C3%A2-mm-but-downsized-by-neo-adjuvant-chemotherapy-is-associated-with-increased-rate-of-local-tumor-progression
#9
Léonor Benhaim, Mostafa El Hajjam, Robert Malafosse, Jacques Sellier, Catherine Julie, Alain Beauchet, Bernard Nordlinger, Frédérique Peschaud
BACKGROUND: Radiofrequency ablation (RFA) is a valid treatment for liver metastases from colorectal cancer (CRLM) smaller than 25 mm and unsuitable for surgical resection. Tumor size is predictive for local tumor progression (LTP). The aim of this study was to evaluate whether RFA is indicated for lesions >25 mm at presentation but <25 mm after chemotherapy. METHOD: Patients who underwent RFA for CRLM after chemotherapy (January 2004-December 2012) were reviewed...
October 10, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29029497/kras-mutation-is-a-marker-of-worse-oncologic-outcomes-after-percutaneous-radiofrequency-ablation-of-colorectal-liver-metastases
#10
Waleed Shady, Elena N Petre, Efsevia Vakiani, Etay Ziv, Mithat Gonen, Karen T Brown, Nancy E Kemeny, Stephen B Solomon, David B Solit, Constantinos T Sofocleous
BACKGROUND: Kras mutation has been associated with shorter overall survival and time to disease recurrence after resection of colorectal liver metastases (CLM). This study evaluated the prognostic value of Kras mutation in patients with CLM treated by percutaneous radiofrequency ablation (RFA). METHODS: This is an IRB waived retrospective analysis of the impact of KRAS mutation status on oncologic outcomes after CLM RFA. The endpoints were overall survival (OS), local tumor progression (LTP) rates, and incidence of new liver, lung, and peritoneal metastases...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29020780/-selective-feticide-in-monochorionic-twin-pregnancies-with%C3%A2-discordant-fetal-anomalies-management-and-outcome
#11
J Vojtěch, L Hašlík, R Pock, K Běhávková, K Macková, P Hanulíková, H Heřman, L Krofta
OBJECTIVE: To analyze results and outcome after selective feticide for discordant anomalies in monochorionic twins. DESIGN: Prospective cohort study. SETTING: Fetal medicine center, Institute for the Care of Mother and Child, Praha. METHODS: Analysis of outcome of monochorionic pregnancies after intrauterine surgery for structural abnormalities between January 2013 and June 2016. RESULTS: We performed 13 intrauterine operations in monochorionic twins with structural anomalies during the period...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/29018051/phase-iii-heat-study-adding-lyso-thermosensitive-liposomal-doxorubicin-to-radiofrequency-ablation-in-patients-with-unresectable-hepatocellular-carcinoma-lesions
#12
Won Young Tak, Shi-Ming Lin, Yijun Wang, Jiasheng Zheng, Aldo Vecchione, Soo Young Park, Min Hua Chen, Stephen Wong, Ruocai Xu, Cheng-Yuan Peng, Yi-You Chiou, Guan-Tarn Huang, Jianqiang Cai, Basri Johan Abdullah, June Sung Lee, Jae Young Lee, Jong Young Choi, Julieta Gopez-Cervantes, Morris Sherman, Richard S Finn, Masao Omata, Michael O'Neal, Lukas Makris, Nicholas Borys, Ronnie Poon, Riccardo Lencioni
PURPOSE: Lyso-thermosensitive liposomal doxorubicin (LTLD) consists of doxorubicin contained within a heat-sensitive liposome. When heated to >=40ºC, LTLD locally releases a high concentration of doxorubicin. We aimed to determine whether adding LTLD improves the efficacy of radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) lesions with a maximum diameter (dmax) of 3 to 7 cm. PATIENTS AND METHODS: The HEAT Study was a randomized, double-blind, dummy-controlled trial of RFA +/- LTLD...
October 10, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28988913/surgical-treatment-strategy-for-hepatocellular-carcinoma-in-patients-with-impaired-liver-function-hepatic-resection-or-radiofrequency-ablation
#13
Takanobu Yamao, Katsunori Imai, Yo-Ichi Yamashita, Takayoshi Kaida, Shigeki Nakagawa, Kosuke Mima, Daisuke Hashimoto, Akira Chikamoto, Takatoshi Ishiko, Hideo Baba
BACKGROUND: To compare the survival impacts of radiofrequency ablation (RFA) as an initial treatment for hepatocellular carcinoma (HCC) in patients with impaired liver functional reserve compared to those of hepatic resection (HR). METHODS: In total, 104 patients with liver damage B as defined by the Liver Cancer Study Group of Japan underwent RFA (n = 33) or HR (n = 71) as an initial treatment for hepatocellular carcinoma. The overall survival (OS) and disease-free survival (DFS) rates were compared, and independent prognostic factors were identified...
October 5, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28983662/radiofrequency-ablation-for-locally-advanced-pancreatic-cancer-smad4-analysis-segregates-a-responsive-subgroup-of-patients
#14
Salvatore Paiella, Giuseppe Malleo, Ivana Cataldo, Clizia Gasparini, Matteo De Pastena, Giulia De Marchi, Giovanni Marchegiani, Borislav Rusev, Aldo Scarpa, Roberto Girelli, Alessandro Giardino, Isabella Frigerio, Mirko D'Onofrio, Erica Secchettin, Claudio Bassi, Roberto Salvia
PURPOSE: SMAD4 mutational status correlates with pancreatic ductal adenocarcinoma (PDAC) failure pattern. We investigated in a subset of locally advanced patients submitted to radiofrequency ablation (RFA) whether the assessment of SMAD4 status is a useful way to select the patients. METHODS: Clinical, radiological, and follow-up details of patients submitted to RFA for locally advanced pancreatic cancer (LAPC), in whom cytohistological material was available at our institution, were retrospectively retrieved...
October 5, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28981400/clinical-outcomes-of-radiofrequency-ablation-for-early-hypovascular-hcc-a-multicenter-retrospective-study
#15
Dong Ho Lee, Jeong Min Lee, Tae Wook Kang, Hyunchul Rhim, So Yeon Kim, Yong Moon Shin, Jung Wook Seo, Moon Hyung Choi, Kyung Bun Lee
Purpose To retrospectively evaluate the clinical outcomes of radiofrequency ablation (RFA) for early hypovascular hepatocellular carcinomas (HCCs) and to compare them with those of typical hypervascular HCCs. Materials and Methods This retrospective multicenter study received institutional review board approval, with a waiver of the need to obtain informed consent. A total of 56 patients (male-to-female ratio, 40:16; mean age, 61.8 years; age range, 33-87 years) with pathologically proven early HCCs that did not meet the noninvasive diagnosis criteria and who were initially treated with RFA at one of five university-affiliated hospitals between January 2009 and December 2013 comprised the study group...
October 5, 2017: Radiology
https://www.readbyqxmd.com/read/28978885/avoidance-of-platelet-transfusion-with-readministration-of-lusutrombopag-before-radiofrequency-ablation-in-hepatocellular-carcinoma-a-case-report
#16
Satoshi Kotani, Naruaki Kohge, Kousuke Tsukano, Sayaka Ogawa, Satoshi Yamanouchi, Ryusaku Kusunoki, Masahito Aimi, Youichi Miyaoka, Hirofumi Fujishiro
Platelet transfusions are generally administered to patients with liver cirrhosis and associated thrombocytopenia before radiofrequency ablation (RFA). Here, we describe a 77-year-old woman who was diagnosed with hepatitis C, liver cirrhosis, and hepatocellular carcinoma (HCC) in 2006. She underwent RFA in October 2014 and October 2015, with platelet transfusions. She was admitted to our hospital in July 2016 to receive RFA for recurrence of HCC. To avoid platelet transfusion before RFA, she was administered lusutrombopag...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28977910/evaluation-of-hepatectomy-and-palliative-local-treatments-for-gastric-cancer-patients-with-liver-metastases-a-propensity-score-matching-analysis
#17
Jiyang Li, Kecheng Zhang, Yunhe Gao, Hongqing Xi, Jianxin Cui, Wenquan Liang, Aizhen Cai, Bo Wei, Lin Chen
BACKGROUND: The optimal treatments for gastric cancer with liver metastases (GCLM) remain controversial. This study aimed to evaluate the efficacy of hepatectomy, RFA and TACE as local treatments for GCLM. METHODS: From 2001 to 2015, 119 consecutive patients who received multidisciplinary treatments based on curative gastrectomy and local treatments (hepatectomy, RFA and TACE) for liver metastases were enrolled in this retrospective cohort study. Patients were divided into Group A (46, hepatectomy) and Group B (73, either or both RFA and TACE)...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28976172/use-of-venoactive-drugs-after-surgery-for-varicose-veins-a-preliminary-study
#18
Daniela Mazzaccaro, Lorenzo Muzzarelli, Alfredo Modafferi, Paolo C Righini, Alberto M Settembrini, Giovanni Nano
BACKGROUND: To assess the use of VenoActive Drugs (VADs) after surgery for chronic venous disease in our Operative Unit in terms of patients' compliance to the therapy and a possible effect on the postoperative pain and QoL. METHODS: Data of consecutive patients who underwent surgery were retrospectively analyzed. All patients, through telephone interview 90 days after the operation, were asked about taking the VAD (either sulodexide or MPFF) which was recommended during the postoperative period...
October 2, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28975641/importance-of-anticoagulation-and-postablation-silent-cerebral-lesions-subanalyses-of-revolution-and-remarqable-studies
#19
Massimo Grimaldi, Vijay Swarup, Brian DeVille, Jonathan Sussman, Pierre Jaïs, Fiorenzo Gaita, Mattias Duytschaever, G Andre Ng, Emile Daoud, Dhanunjaya Dj Lakkireddy, Rodney Horton, Andrew Wickliffe, Christopher Ellis, Laszlo Geller
BACKGROUND: Silent cerebral lesions (SCLs) are a potential complication of left atrial radiofrequency ablation (RFA) procedures for paroxysmal atrial fibrillation (PAF). We aimed to compare the incidence of SCLs in patients treated with irrigated RFA multielectrode catheters (nMARQ® Catheter group) and irrigated focal RFA catheters (NAVISTAR® THERMOCOOL® Catheter; TC group) after PAF ablation from subpopulation neurological assessment (SNA) cohorts of the REVOLUTION and reMARQable studies...
October 4, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28975074/cooled-radiofrequency-ablation-of-genicular-nerves-for-knee-osteoarthritis-pain-a-protocol-for-patient-selection-and-case-series
#20
Rajiv D Reddy, Zachary L McCormick, Ben Marshall, Ryan Mattie, David R Walega
BACKGROUND: Chronic knee pain from osteoarthritis (OA) is common in the aging and the obese population. Radiofrequency ablation of the genicular nerves has been introduced as a potential surgery-sparing treatment for chronic knee pain from OA, yet only two outcome studies have been published and optimal patient selection for this procedure has not been established. OBJECTIVES: We describe a standardized protocol for selecting patients for cooled radiofrequency ablation (C-RFA) of the genicular nerves, as well as the clinical outcomes of four patients ages 63-65 years...
December 2016: Anesthesiology and Pain Medicine
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