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https://www.readbyqxmd.com/read/28645556/breast-cancer-liver-metastases-in-a-uk-tertiary-centre-outcomes-following-referral-to-tumour-board-meeting
#1
Hiba Abbas, Simon Erridge, Mikael H Sodergren, Michail Papoulas, Aamir Nawaz, Krishna Menon, Nigel D Heaton, Andreas A Prachalias, Parthi Srinivasan
INTRODUCTION: To assess the outcomes from multidisciplinary board meetings (MDM) for patients with breast cancer liver metastases (BCLM) and identify prognostic factors for survival. MATERIALS AND METHODS: A retrospective review of MDM records for patients referred with BCLM to a tertiary centre between 2005-2016. Patient demographics, clinicopathological factors and intervention type were analysed to find predictive factors for overall survival. RESULTS: 61 patients with BCLM were referred to the MDM...
June 20, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28643305/-interventional-therapy-of-colorectal-liver-metastasis
#2
Qi Zhang, Gaojun Teng
Colorectal liver metastasis (CRLM) is one of the most difficult and key points in the treatment of colorectal cancer. Approximately 50% to 60% of patients diagnosed as colorectal cancer develops metastasis, and 80% to 90% of CRLM is unresectable. Surgical resection is the first-line treatment for CRLM, while it is only suitable for about 15% patients. Systemic chemotherapy can prolong the survival of CRLM patients, however, a part of CRLM patients are resistant to chemotherapy. With the development of technology and the update of clinical evidence, individual therapy with target drugs and multidisciplinary treatment (MDT) have became a tendency, and minimally invasive interventional therapy has gained more acceptance in the MDT mode of the treatment for CRLM...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28640176/ultrasound-guided-percutaneous-radiofrequency-ablation-of-liver-metastasis-from-ovarian-cancer-a-single-center-initial-experience
#3
Baoxian Liu, Guangliang Huang, Chunlin Jiang, Ming Xu, Bowen Zhuang, Manxia Lin, Wenshuo Tian, Xiaohua Xie, Ming Kuang, Xiaoyan Xie
OBJECTIVE: The aim of this study was to evaluate the feasibility, effectiveness, and safety of ultrasound-guided percutaneous radiofrequency ablation (RFA) for the treatment of liver metastasis from ovarian cancer (OC). METHODS: A retrospective review was performed on 11 patients (mean age, 53.0 ± 10.1 years) with 22 liver metastases (mean diameter, 2.0 ± 0.8 cm) from OC undergone RFA. Radiofrequency ablation was carried out with Starburst XL electrodes (RITA Medical System, Mountain View, CA) or Cool-tip electrodes (Cool-tip Systems; Valleylab, Boulder, CO)...
July 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28635504/applying-rasch-model-analysis-in-the-development-of-the-cantonese-tone-identification-test-cantit
#4
Kathy Y S Lee, Joffee H S Lam, Kit T Y Chan, Charles Andrew van Hasselt, Michael C F Tong
OBJECTIVE: Applying Rasch analysis to evaluate the internal structure of a lexical tone perception test known as the Cantonese Tone Identification Test (CANTIT). DESIGN: A 75-item pool (CANTIT-75) with pictures and sound tracks was developed. Respondents were required to make a four-alternative forced choice on each item. A short version of 30 items (CANTIT-30) was developed based on fit statistics, difficulty estimates, and content evaluation. Internal structure was evaluated by fit statistics and Rasch Factor Analysis (RFA)...
March 1, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28628718/a-better-method-for-assessment-of-hepatic-function-in-hcc-patients-who-underwent-radiofrequency-ablation-usefulness-of-albumin-bilirubin-grade
#5
Atsushi Hiraoka, Takashi Kumada, Masashi Hirooka, Kunihiko Tsuji, Ei Itobayashi, Kazuya Kariyama, Toru Ishikawa, Kazuto Tajiri, Hirofumi Ochi, Toshifumi Tada, Hidenori Toyoda, Kazuhiro Nouso, Kouji Joko, Hideki Kawasaki, Yoichi Hiasa, Kojiro Michitaka
AIM/BACKGROUND: To evaluate the efficacy of the newly proposed albumin-bilirubin (ALBI)-grade for therapy selection, clinical features of patients treated with radiofrequency ablation (RFA) were elucidated. MATERIALS/METHODS: From 2000 to 2015, 1101 patients with HCC (<3 cm, ≤3 tumors) treated with RFA were enrolled [males 734, females 367; HCV:HBV:HCV&HBV:others=779:153:5:164; Child-Pugh classification (CP) A:B=842:259]. Liver damage classification (LD) using with ICG-R15 and ALBI-grade were compared in regard to the prognoses of those patients...
June 19, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/28623986/double-prepuncture-as-a-valuable-adjunctive-technique-for-complex-endovenous-ablation
#6
Scarlett Hao, Samantha Cox, Thomas S Monahan, Rajabrata Sarkar
OBJECTIVE: The objective of this study was to characterize the technique and to report the results of double prepuncture used during complex radiofrequency ablation (RFA) in cases of treating multiple incompetent veins or encountering focal obstruction to catheter advancement. METHODS: A double prepuncture technique was applied in patients requiring endovascular ablation of multiple veins and patients with great saphenous vein cannulation failure. We treated 13 limbs in 12 patients during a 24-month period with RFA in which the double prepuncture technique was used...
July 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28623296/iodine-125-brachytherapy-prophylaxis-after-radiofrequency-ablation-cannot-benefit-patients-in-high-risk-of-locoregional-hepatocellular-carcinoma-recurrence
#7
Jian-Fei Tu, Ya-Hui Ding, Li Chen, Xi-Hui Ying, Deng-Ke Zhang, Fa-Zong Wu, Zhong-Wei Zhao, Jian-Song Ji, Wang-Gang Zhang, Hai Zou
This study evaluated if iodine-125 brachytherapy prophylaxis after radiofrequency ablation (RFA) prolongs time to recurrence (TTR) and overall survival (OS) of patients in high risk of locoregional hepatocellular carcinoma (HCC) recurrence. 116 patients with total tumor necrosis after RFA were divided into iodine-125 brachytherapy prophylaxis treatment group and control group. The primary endpoint was TTR, and secondary endpoints were OS and treatment-related adverse events. There were no significant differences among the baseline characteristics of two subgroups patients...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28612670/optimal-approach-for-complete-liver-tumor-ablation-using-radiofrequency-ablation-a-simulation-study
#8
Sogol Givehchi, Yin How Wong, Chai Hong Yeong, Basri Johan Jeet Abdullah
PURPOSE: To investigate the effect of radiofrequency ablation (RFA) electrode trajectory on complete tumor ablation using computational simulation. MATERIAL AND METHODS: The RFA of a spherical tumor of 2.0 cm diameter along with 0.5 cm clinical safety margin was simulated using Finite Element Analysis software. A total of 86 points inside one-eighth of the tumor volume along the axial, sagittal and coronal planes were selected as the target sites for electrode-tip placement...
June 14, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28612019/thermal-ablation-in-the-management-of-colorectal-cancer-patients-with-oligometastatic-liver-disease
#9
REVIEW
Elena Nadia Petre, Constantinos Sofocleous
BACKGROUND: Surgical resection of limited colorectal liver disease improves long-term survival and can be curative in a subset of selected cases. Image-guided percutaneous ablation therapies have emerged as safe and effective alternative options for selected patients with unresectable colorectal liver metastases (CLM) that can be ablated with margins. Ablation causes focal destruction of tissue and has increasingly been shown to provide durable eradication of tumors. METHODS: A selective review of literature was conducted in PubMed, focusing on recent studies reporting on the safety, efficacy, and long-term outcomes of percutaneous ablation modalities in the treatment of CLM...
March 2017: Visceral Medicine
https://www.readbyqxmd.com/read/28605944/a-comparison-of-laser-with-radiofrequency-ablation-for-the-treatment-of-benign-thyroid-nodules-a-propensity-score-matching-analysis
#10
Claudio Maurizio Pacella, Giovanni Mauri, Roberto Cesareo, Valerio Paqualini, Roberto Cianni, Pierpaolo De Feo, Giovanni Gambelunghe, Bruno Raggiunti, Doris Tina, Maurilio Deandrea, Pier Paolo Limone, Alberto Mormile, Massimo Giusti, Silvia Oddo, Gaetano Achille, Enrico Di Stasio, Irene Misischi, Enrico Papini
PURPOSE: To compare technique efficacy and safety of laser ablation (LA) and radiofrequency ablation (RFA) in treatment of benign thyroid nodules. MATERIALS AND METHODS: Institutional review board approval was obtained, and patients' consent was waived. 601 nodules were treated from May 2009 to December 2014 at eight centres, 449 (309 females, age 57 ± 14 years) with LA and 152 (107 females, age 57 ± 14 years) with RFA. A matched cohort composed of 138 patients from each group was selected after adjustment with propensity score matching...
June 12, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28605745/current-standard-and-future-perspectives-in-non-surgical-therapy-for-hepatocellular-carcinoma
#11
Tobias Eggert, Tim F Greten
BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive liver tumor with a poor 5-year survival rate. Many HCCs are not amenable to surgical resection, because of tumor size, location, or because of the patient's poor liver function, a common obstacle to HCC therapy, because HCCs almost always develop in chronically inflamed livers. SUMMARY: In recent years, many efforts have been made to improve patient survival by conducting clinical trials investigating local and systemic treatment options for patients with unresectable tumors...
June 13, 2017: Digestion
https://www.readbyqxmd.com/read/28604580/solidification-and-biotoxicity-assessment-of-thermally-treated-municipal-solid-waste-incineration-mswi-fly-ash
#12
Bing Gong, Yi Deng, Yuanyi Yang, Swee Ngin Tan, Qianni Liu, Weizhong Yang
In the present work, thermal treatment was used to stabilize municipal solid waste incineration (MSWI) fly ash, which was considered hazardous waste. Toxicity characteristic leaching procedure (TCLP) results indicated that, after the thermal process, the leaching concentrations of Pb, Cu, and Zn decreased from 8.08 to 0.16 mg/L, 0.12 to 0.017 mg/L and 0.39 to 0.1 mg/L, respectively, which well met the limits in GB5085.3-2007 and GB16689-2008. Thermal treatment showed a negative effect on the leachability of Cr with concentrations increasing from 0...
June 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28601921/the-history-of-autonomy-in-medicine-from-antiquity-to-principlism
#13
Toni C Saad
Respect for Autonomy (RFA) has been a mainstay of medical ethics since its enshrinement as one of the four principles of biomedical ethics by Beauchamp and Childress' in the late 1970s. This paper traces the development of this modern concept from Antiquity to the present day, paying attention to its Enlightenment origins in Kant and Rousseau. The rapid C20th developments of bioethics and RFA are then considered in the context of the post-war period and American socio-political thought. The validity and utility of the RFA are discussed in light of this philosophical-historical account...
June 10, 2017: Medicine, Health Care, and Philosophy
https://www.readbyqxmd.com/read/28600235/semi-automatic-radiofrequency-ablation-planning-based-on-constrained-clustering-process-for-hepatic-tumors
#14
Rendong Chen, Tian'an Jiang, Fang Lu, Kaifeng Wang, Dexing Kong
Radiofrequency ablation (RFA) is currently one of the most effective methods for minimally invasive treatment of hepatic tumors. Planning the probe placements is an essential and challenging step in RFA treatment. To completely destroy the tumor with minimum amount of affected native tissue, a new RFA planning system is proposed in this paper. In the proposed planning system, the minimum number of ablations and a conical insertion region for each ablation session are determined automatically. Based on the geometric character of the tumor, a novel clustering algorithm is developed to allow a better layout of the overlapping ablations...
June 5, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28598835/efficacy-of-contrast-enhanced-ultrasound-for-immediate-assessment-of-ablation-status-after-intraoperative-radiofrequency-ablation-of-hepatic-malignancies
#15
N Platz Batista da Silva, L P Beyer, M C Hottenrott, C Hackl, H J Schlitt, C Stroszczynski, P Wiggermann, E M Jung
AIM: To evaluate the Efficacy of intraoperative contrast enhanced ultrasound (Io-CEUS) for assessment of radiofrequency ablation (RFA) during liver tumor surgery. MATERIAL AND METHODS: Retrospective analyis was performed on 18 patients who underwent combined liver tumor surgery and RFA of 27 hepatic tumors between 02/2011 and 12/2016. Io-CEUS was performed by bolus injections of up to 10 ml sulphur hexaflourid microbubbles for diagnostic purposes. To guide the RFA up to 20 ml microbubbles were applied to monitor the procedure and assess the ablation status finally...
June 3, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28597707/ct-guided-radiofrequency-ablation-of-spinal-osteoblastoma-treatment-and-long-term-follow-up
#16
Francesco Arrigoni, Antonio Barile, Luigi Zugaro, Eva Fascetti, Marcello Zappia, Luca Brunese, Carlo Masciocchi
OBJECTIVE: Osteoblastoma (OB) is a painful, rare, benign bone tumour usually observed in young populations, and this condition involves the spine in up to one-third of cases. We sought to focus on the minimally invasive treatment of spinal OB with radiofrequency ablation (RFA) under computed tomography (CT) guidance. When performed near the spinal cord, surgery can lead to instability of the spine, sometimes requiring additional interventions to stabilise the segments involved, and can cause the precocious onset of arthrosis or other degenerative diseases...
June 9, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28588677/comparative-study-of-conventional-us-contrast-enhanced-us-and-enhanced-mr-for-the-follow-up-of-prostatic-radiofrequency-ablation
#17
Chao Feng, Bin Hu, Bing Hu, Lei Chen, Jia Li, Jin Huang
The aim of the present study was to evaluate and compare the effectiveness of different imaging methods during follow-up of prostatic radiofrequency ablation. Prostatic radiofrequency ablation (RFA) was performed in 20 healthy beagle dogs. Various imaging examinations were used to monitor the results of RFA, including conventional ultrasound (US), contrast enhanced ultrasound (CEUS) and enhanced magnetic resonance (MR). Imaging exams were performed at five phases: Immediately following RFA, one week later, one month later, three months later and six months later...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28586250/pain-after-percutaneous-irreversible-electroporation-of-renal-tumors-is-not-dependent-on-tumor-location
#18
Igor Sorokin, Aaron H Lay, Nikitha K Reddy, Noah E Canvasser, Murthy Chamarthy, Jeffrey A Cadeddu
Introduction Irreversible electroporation (IRE) is a non-thermal minimally invasive technique to treat small renal masses (SRM). Prior work has demonstrated greater narcotic requirements after radiofrequency ablation (RFA) for tumors closer to body-wall musculature. We hypothesized that pain after IRE is not dependent on tumor location due to the athermal mechanistic action. Methods Retrospective review of 50 consecutive percutaneous IRE and RFA cases was performed from 2013 to 2014. Eight patients were excluded from analysis due to incomplete anesthesia record and/or multiple ablations per session leaving 21 patients in each group...
June 6, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28582848/curative-effect-of-transcatheter-arterial-chemoembolization-combined-with-radiofrequency-ablation-in-treating-hepatic-cell-carcinoma-and-its-effect-on-serum-markers
#19
Fu-Qiang Jiang, Wei Lu, Chao Yang, Peng Du, Jun-Peng Ma, Jian Yang, Peng Xie, Zhe Zhang
BACKGROUND: Hepatic cell carcinoma (HCC) is more common in clinical practice, and has high malignant degree. OBJECTIVE: This study aims to analyze the curative effect of transcatheter arterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) in treating hepatic cell carcinoma (HCC) and its effect on serum markers. METHODS: A total of 106 cases of patients with hepatic cell carcinoma treated in our hospital were randomly divided into two groups: observation group and control group...
May 26, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28581404/treatment-related-toxicity-in-patients-with-early-stage-non-small-cell-lung-cancer-and-coexisting-interstitial-lung-disease-a-systematic-review
#20
REVIEW
Hanbo Chen, Suresh Senan, Esther J Nossent, R Gabriel Boldt, Andrew Warner, David A Palma, Alexander V Louie
PURPOSE: Definitive treatment for patients with early-stage non-small cell lung cancer (ES-NSCLC) is usually well tolerated. Patients with ES-NSCLC and coexisting interstitial lung disease (ILD) are at increased risk of severe treatment-related toxicity after definitive therapy. The main objective of this systematic review is to provide a pooled estimation of treatment-related mortality and ILD-specific toxicity in this population of patients and to identify trends for further study. METHODS AND MATERIALS: The MEDLINE and Embase databases were queried from respective dates of inception to January 2016...
July 1, 2017: International Journal of Radiation Oncology, Biology, Physics
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