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Attention deficit / hyperactivity disorders

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https://www.readbyqxmd.com/read/29332109/prevalence-of-attention-deficit-hyperactivity-disorder-and-comorbid-psychiatric-and-behavioral-problems-among-primary-school-students-in-western-saudi-arabia
#1
Faten N AlZaben, Mohammad G Sehlo, Waleed A Alghamdi, Haythum O Tayeb, Doaa A Khalifa, Abdulrahman T Mira, Abdulaziz M Alshuaibi, Mosab A Alguthmi, Ahmad A Derham, Harold G Koenig
To determine the prevalence of attention deficit hyperactivity disorder (ADHD), subtypes of ADHD, and psychiatric, academic, and behavioral comorbidity in public primary school students in Jeddah, Saudi Arabia.  Methods: This is a cross-sectional study. A simple random sample of 6 primary government schools in Jeddah, Saudi Arabia, was identified (3 male, 3 female), and a random sample of classes in each of grades 1-6 were selected. Between July and November 2016, teachers in these classes were asked to complete the Vanderbilt ADHD scale on all students in their classes...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29332099/association-between-the-intron-8-vntr-polymorphism-of-the-dat1-gene-and-crack-cocaine-addiction
#2
Anderson R Stolf, Diana Müller, Jaqueline B Schuch, Gláucia C Akutagava-Martins, Luciano S P Guimaraes, Claudia M Szobot, Ricardo Halpern, Felix H P Kessler, Flavio Pechansky, Tatiana Roman
BACKGROUND: This study aims to compare allele and genotype frequencies of a 30-bp variable number of tandem repeats (VNTR) polymorphism of the DAT1 gene, located at intron 8, between adult crack cocaine users and nonaddicted individuals. Due to its involvement in drug addiction, this gene is a good candidate for molecular studies. METHODS: A cross-sectional sample of 239 current adult crack abusers or dependents from in- and outpatient clinics and 211 control individuals was collected in Brazil...
January 12, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29331354/specificity-in-etiology-of-subtypes-of-bipolar-disorder-evidence-from-a-swedish-population-based-family-study
#3
Jie Song, Ralf Kuja-Halkola, Arvid Sjölander, Sarah E Bergen, Henrik Larsson, Mikael Landén, Paul Lichtenstein
BACKGROUND: Uncertainty remains whether bipolar I disorder (BDI) and bipolar II disorder (BDII) differ etiologically. We used a population-based family sample to examine the etiological boundaries between BDI and BDII by assessing their familial aggregation/coaggregation and by assessing the coaggregation between them and schizophrenia, depression, attention-deficit/hyperactivity disorder, eating disorders, autism spectrum disorder, substance use disorders, anxiety disorders, and personality disorders...
November 20, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29325848/a-genetic-investigation-of-sex-bias-in-the-prevalence-of-attention-deficit-hyperactivity-disorder
#4
Joanna Martin, Raymond K Walters, Ditte Demontis, Manuel Mattheisen, S Hong Lee, Elise Robinson, Isabell Brikell, Laura Ghirardi, Henrik Larsson, Paul Lichtenstein, Nicholas Eriksson, Thomas Werge, Preben Bo Mortensen, Marianne Giørtz Pedersen, Ole Mors, Merete Nordentoft, David M Hougaard, Jonas Bybjerg-Grauholm, Naomi R Wray, Barbara Franke, Stephen V Faraone, Michael C O'Donovan, Anita Thapar, Anders D Børglum, Benjamin M Neale
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) shows substantial heritability and is two to seven times more common in male individuals than in female individuals. We examined two putative genetic mechanisms underlying this sex bias: sex-specific heterogeneity and higher burden of risk in female cases. METHODS: We analyzed genome-wide autosomal common variants from the Psychiatric Genomics Consortium and iPSYCH Project (n = 20,183 cases, n = 35,191 controls) and Swedish population register data (n = 77,905 cases, n = 1,874,637 population controls)...
December 2, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29325731/pharmacogenomic-testing-in-child-and-adolescent-psychiatry-an-evidence-based-review
#5
Anna M Wehry, Laura Ramsey, Shane E Dulemba, Sarah A Mossman, Jeffrey R Strawn
Significant advances have been made in the application of pharmacogenomic testing for the treatment of patients with psychiatric disorders. Over the past decade, a number of studies have evaluated the utility of pharmacogenomic testing in pediatric patients with psychiatric disorders. The evidence base for pharmacogenomic testing in youth with depressive and anxiety disorders as well as attention/deficit hyperactivity disorder (ADHD) is reviewed in this article. General pharmacogenomic principles are summarized and functional polymorphisms in P450 enzymes (and associated metabolizer phenotypes), the serotonin transporter promoter polymorphisms, serotonin 2 A receptor genes (e...
January 8, 2018: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/29325223/maternal-thyroid-hormone-insufficiency-during-pregnancy-and-risk-of-neurodevelopmental-disorders-in-offspring-a-systematic-review-and-meta-analysis
#6
William Thompson, Ginny Russell, Genevieve Baragwanath, Justin Matthews, Bijay Vaidya, Jo Thompson-Coon
BACKGROUND: In the last two decades, several studies have examined the association between maternal thyroid hormone insufficiency during pregnancy and neurodevelopmental disorders in children and shown conflicting results. AIM: This systematic review aimed to assess the evidence for an association between maternal thyroid hormone insufficiency during pregnancy and neurodevelopmental disorders in children. We also sought to assess whether levothyroxine treatment for maternal thyroid hormone insufficiency improves child neurodevelopment outcomes...
January 11, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29324475/bilateral-cochlear-implants-maximizing-expected-outcomes
#7
Kate E Willis, Nathan J Blum, Stephanie A Waryasz, Marilyn Augustyn
Sonia is a 4 1/12-year-old girl with Waardenburg syndrome and bilateral sensorineural hearing loss who had bilateral cochlear implants at 2 7/12 years of age. She is referred to Developmental-Behavioral Pediatrics by her speech/language pathologist because of concerns that her language skills are not progressing as expected after the cochlear implant. At the time of the implant, she communicated using approximately 20 signs and 1 spoken word (mama). At the time of the evaluation (18 months after the implant) she had approximately 70 spoken words (English and Spanish) and innumerable signs that she used to communicate...
January 10, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29324397/serum-levels-of-cortisol-dehydroepiandrosterone-and-oxytocin-in-children-with-attention-deficit-hyperactivity-disorder-combined-presentation-with-and-without-comorbid-conduct-disorder
#8
Ümit Işık, Ayhan Bilgiç, Aysun Toker, Ibrahim Kılınç
The present study aimed to investigate serum cortisol, dehydroepiandrosterone (DHEA), and oxytocin levels of children with attention-deficit/hyperactivity disorder (ADHD) combined presentation and those diagnosed with ADHD combined presentation and coexisting conduct disorder. A total of 74 drug-naive children with ADHD combined presentation alone, 32 children with ADHD combined presentation + conduct disorder, and 42 healthy controls were included. The severities of ADHD and conduct disorder symptoms were assessed via parent- and teacher-rated questionnaires...
January 2, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29323926/investigating-effects-of-sex-differences-and-prior-concussions-on-symptom-reporting-and-cognition-among-adolescent-soccer-players
#9
Brian L Brooks, Noah Silverberg, Bruce Maxwell, Rebekah Mannix, Ross Zafonte, Paul D Berkner, Grant L Iverson
BACKGROUND: There has been increasing concern regarding the possible effect of multiple concussions on the developing brain, especially for adolescent females. Hypothesis/Purpose: The objectives were to determine if there are differences in cognitive functioning, symptom reporting, and/or sex effects from prior concussions. In a very large sample of youth soccer players, it was hypothesized that (1) there would be no differences in cognitive test performance between those with and without prior concussions, (2) baseline preseason symptoms would be better predicted by noninjury factors than concussion history, and (3) males and females with prior concussions would not have differences in cognition or symptoms...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29323553/revealing-the-structural-neural-circuitry-of-attention-deficit-hyperactivity-disorder-with-diffusion-mri-implications-for-future-diagnosis-and-treatment
#10
Vitria Adisetiyo
OBJECTIVE: Rates of attention deficit hyperactivity disorder (ADHD) diagnosis and psychostimulant prescriptions continue to rise, yet there are no clear diagnostic tests or biomarkers for the disorder. The purpose of this article is to highlight the role of diffusion MRI in bolstering a neurobiologic conceptualization of ADHD and how this holds promise for optimizing future diagnosis. CONCLUSION: Diffusion MRI is a powerful neuroimaging tool for noninvasive assessment of the structural neural circuitry underlying brain function and behavior...
January 11, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29321993/sansoninto-a-traditional-herbal-medicine-ameliorates-behavioral-abnormalities-and-down-regulation-of-early-growth-response-1-expression-in-mice-exposed-to-social-isolation-stress
#11
Hironori Fujiwara, Ryohei Tsushima, Ryo Okada, Suresh Awale, Ryota Araki, Takeshi Yabe, Kinzo Matsumoto
Social isolation (SI) mice exhibit behavioral abnormalities such as impairments of sociability- and attention-like behaviors, offering an animal model of neurodevelopmental disorders such as attention-deficit/hyperactivity disorder (ADHD). This study aimed to identify the effects of Sansoninto (SST; suān zǎo rén tāng) on the psychiatric symptoms related to ADHD using SI mice. Four-week-old mice were socially isolated during the experimental period, and SST administration (800 or 2400 mg/kg, p.o.) was started at 2 weeks after starting SI...
January 2018: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29321705/attention-deficit-hyperactivity-disorder-and-nicotine-dependence-in-adults
#12
Bülent Bilgi, Umut Mert Aksoy, Özge Şahmelikoğlu Onur, Ayşe Fulya Maner
Introduction: The aim of this study is to assess clinical characteristics and smoking profiles of individuals diagnosed with attention-deficit/hyperactivity disorder (ADHD) and compare their nicotine dependence status with healthy controls for better understanding the mutual and complex relationship between ADHD and smoking. Methods: We included the following participants in the study: 40 adults with the diagnosis of ADHD, 40 participants who visited the smoking cessation polyclinic without any psychiatric disorders, and 40 healthy controls...
December 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/29320782/thyroid-hormone-status-in-overweight-children-with-attention-deficit-hyperactivity-disorder
#13
Christian Langrock, Johannes Hebebrand, Katharina Radowksi, Eckard Hamelmann, Thomas Lücke, Martin Holtmann, Tanja Legenbauer, Börge Schmidt, Mirjam Frank, Karl-Heinz Jöckel, Thomas Reinehr
BACKGROUND: There is an ongoing discussion whether thyroid hormones are involved in the development and course of attention deficit/hyperactivity disorder (ADHD). Since obesity is associated with both higher thyroid-stimulating hormone (TSH) and free triiodothyronine (fT3) concentrations and increased rates of ADHD, we hypothesized that overweight children with ADHD show higher TSH and fT3 concentrations compared to overweight children without ADHD. METHODS: TSH, fT3, fT4, and leptin levels were analyzed in 230 children (60...
January 10, 2018: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29320768/attention-deficit-hyperactivity-disorder-symptoms-are-common-in-patients-in-opioid-maintenance-treatment
#14
Kristine Fiksdal Abel, Edle Ravndal, Thomas Clausen, Jørgen G Bramness
INTRODUCTION AND AIMS: Knowledge of attention deficit hyperactivity disorder (ADHD) symptoms among patients in opioid maintenance treatment (OMT) is important for treatment optimization and yet limited. We investigated the prevalence of ADHD symptoms, and factors associated with high ADHD symptom burden in a group of Norwegian OMT patients. METHODS: We interviewed individuals entering OMT across Norway in 2 steps between 2012 and 2016. ADHD symptoms were measured by the Adult ADHD Self-Report Scale (ASRS; n = 175)...
January 10, 2018: European Addiction Research
https://www.readbyqxmd.com/read/29318132/the-effectiveness-of-mhealth-apps-in-the-rehabilitation-of-children-with-attention-deficit-hyperactivity-disorder
#15
Azadeh Bashiri, Marjan Ghazisaeedi
No abstract text is available yet for this article.
January 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29317844/a-survey-of-adult-referrals-to-specialist-attention-deficit-hyperactivity-disorder-clinics-in-canada
#16
Larry J Klassen, C Matthew Blackwood, Christopher J Reaume, Samuel Schaffer, James G Burns
Background: Canadian guidelines encourage family physicians to diagnose/manage adults with uncomplicated attention-deficit/hyperactivity disorder (ADHD); specialist referral is recommended only for complex cases. This retrospective case review investigated adults referred to Canadian ADHD clinics. Methods: Adult ADHD specialists reviewed referral letters/charts of patients (aged ≥18 years and no family history/known/expressed childhood ADHD) from family physicians/psychiatrists over 2 years...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29317442/maternal-adhd-symptoms-child-adhd-symptoms-and-broader-child-outcomes
#17
Daryl Efron, Kirsten Furley, Alisha Gulenc, Emma Sciberras
OBJECTIVE: This study investigated the associations between maternal symptoms of attention deficit hyperactivity disorder (ADHD) and child functional outcomes in a community-based sample of children with and without ADHD. DESIGN AND SETTING: In this cohort study, children with ADHD and healthy controls were recruited through schools in Melbourne, Australia, using a combined screening (Conners 3 ADHD Index) and case confirmation (Diagnostic Interview Schedule for Children Version IV) procedure...
January 9, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29317441/chronic-tic-disorders-in-children-with-adhd
#18
William Poh, Jonathan M Payne, Alisha Gulenc, Daryl Efron
OBJECTIVE: To examine in a community-based cohort: (1) the prevalence of chronic tic disorder (CTD) in children with attention-deficit/hyperactivity disorder (ADHD) compared with non-ADHD controls at ages 7 and 10; and (2) the additional psychiatric and functional burden of CTD in children with ADHD. METHODS: Children aged 6-8 years with ADHD (n=179) and controls (n=212) were recruited through 43 Victorian schools using parent and teacher screening surveys (Conners 3 ADHD Index), followed by case confirmation (Diagnostic Interview Schedule for Children-IV (DISC-IV))...
January 9, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29316800/pro-dopamine-regulator-kb220z-attenuates-hoarding-and-shopping-behavior-in-a-female-diagnosed-with-sud-and-adhd
#19
Thomas McLaughlin, Kenneth Blum, Bruce Steinberg, Edward J Modestino, Lyle Fried, David Baron, David Siwicki, Eric R Braverman, Rajendra D Badgaiyan
Background Addictive-like behaviors (e.g., hoarding and shopping) may be the result of the cumulative effects of dopaminergic and other neurotransmitter genetic variants as well as elevated stress levels. We, therefore, propose that dopamine homeostasis may be the preferred goal in combating such challenging and unwanted behaviors, when simple dopaminergic activation through potent agonists may not provide any resolution. Case presentation C.J. is a 38-year-old, single, female, living with her mother. She has a history of substance use disorder as well as attention deficit hyperactivity disorder, inattentive type...
January 10, 2018: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29316105/antidepressant-use-during-pregnancy-and-adhd-risk-in-children-current-knowledge
#20
Takoua Boukhris
Antidepressants (ADs) are among the most frequently used medications in pregnancy. ADs can cross the placental barrier (Rampono et al. Pharmacopsychiatry 2009;42(3):95-100, Loughhead et al. Biol Psychiatry 2006;59(3):287-90), resulting in a dysfunction of the serotonergic and norepinephrine systems, which could cause inattention or hyperactivity-impulsivity behaviors as exhibited in ADHD. Several epidemiological studies have investigated the potential link between AD exposure during pregnancy and the risk of attention deficit disorder with/without hyperactivity (ADHD) in children...
January 9, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
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