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S Y Choi, J Seok, H J Kwon, T R Kwon, B J Kim
Among the non-surgical treatment modalities, injection of hyaluronic acid (HA) filler has become the popular cosmetic procedure for reducing wrinkles.(1) The forehead wrinkles require larger volumes of HA filler than other areas of the face. In this randomized, placebo-controlled, clinical trial, we investigated the efficacy and safety of a pneumatic microjet device (Innojector(™) ; Amore Pacific, Seoul, Korea) that delivers hyaluronic acid (HA), (Restylene Skinboosters(®) ; Q-Medical, Uppsala, Sweden) into the dermis via pneumatic needleless or multi-needle injection in order to improve forehead wrinkles...
August 9, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Marina Landau, Steven Fagien
Loss of viscoelasticity is one of the primarily signs of skin aging, followed by appearance of visible wrinkles. Hyaluronic acid (HA)-based fillers are widely used to fill wrinkles and compensate for volume loss. Recent clinical observations demonstrate persistence of the filling effect longer than the biological availability of the filler. Stimulation of new collagen by cross-linked HA and up-regulation of elastin have been suggested as possible explanation to this observation and have been supported experimentally...
November 2015: Plastic and Reconstructive Surgery
Vince Bertucci, Carrie B Lynde
BACKGROUND: Soft-tissue augmentation with hyaluronic acid (HA) fillers has become one of the most popular cosmetic procedures performed. HA fillers represent safe and commonly used fillers. Several different HA fillers are available. The differences lie in the manufacturing process, allowing for tailored uses. A small-particle HA with lidocaine (SP-HAL; Restylane Silk; Galderma, Uppsala, Sweden) was approved by the US Food and Drug Administration in June 2014 but has been available for many years in Canada as Restylane Fine Lines and in Europe as Restylane Vital...
November 2015: Plastic and Reconstructive Surgery
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