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JOURNAL ARTICLE
Austin J Bordelon, Paige Wilson, Bailey Book, Carrie Baker, Bryan J Donald
Background Pharmacists can modify prescriptions from prescribers for clarity and patient understanding, provided the confines of the original order are met, yet the verbiage used by pharmacists is not standardized. Prescription directions for children, especially children eight years old and younger, should be written with the verb "give" instead of "take" as their parents or caregivers are expected to administer them. Errors in prescribing, dispensing, and administering medication comprise a significant portion of preventable medical errors in children...
March 2024: Curēus
#2
JOURNAL ARTICLE
Donald L Peden, Robert Rogers, Emma A Mitchell, Suzanne M Taylor, Stephen J Bailey, Richard A Ferguson
The asymptote (critical power; CP) and curvature constant (W') of the hyperbolic power-duration relationship can predict performance within the severe-intensity exercise domain. However, the extent to which these parameters relate to skeletal muscle mitochondrial content and respiratory function is not known. Fifteen males (peak O2 uptake, 52.2 ± 8.7 mL kg-1 min-1 ; peak work rate, 366 ± 40 W; and gas exchange threshold, 162 ± 41 W) performed three to five constant-load tests to task failure for the determination of CP (246 ± 44 W) and W' (18...
April 9, 2024: Experimental Physiology
#3
JOURNAL ARTICLE
Bailey A Martin-Giacalone, He Li, Michael E Scheurer, Dana L Casey, Shannon Dugan-Perez, Deborah A Marquez-Do, Donna Muzny, Richard A Gibbs, Donald A Barkauskas, David Hall, Douglas R Stewart, Joshua D Schiffman, Matthew T McEvoy, Javed Khan, David Malkin, Corinne M Linardic, Brian D Crompton, Jack F Shern, Stephen X Skapek, Rajkumar Venkatramani, Douglas S Hawkins, Aniko Sabo, Sharon E Plon, Philip J Lupo
IMPORTANCE: Determining the impact of germline cancer-predisposition variants (CPVs) on outcomes could inform novel approaches to testing and treating children with rhabdomyosarcoma. OBJECTIVE: To assess whether CPVs are associated with outcome among children with rhabdomyosarcoma. DESIGN, SETTING, AND PARTICIPANTS: In this cohort study, data were obtained for individuals, aged 0.01-23.23 years, newly diagnosed with rhabdomyosarcoma who were treated across 171 Children's Oncology Group sites from March 15, 1999, to December 8, 2017...
March 4, 2024: JAMA Network Open
#4
Marta I Mulawa, Sharron L Docherty, Donald E Bailey, Rosa M Gonzalez-Guarda, Isaac M Lipkus, Schenita D Randolph, Qing Yang, Wei Pan
No abstract text is available yet for this article.
March 27, 2024: Prevention Science: the Official Journal of the Society for Prevention Research
#5
JOURNAL ARTICLE
Sherry-Ann Brown, Craig Beavers, Brenton Bauer, Richard K Cheng, Generika Berman, Catherine H Marshall, Avirup Guha, Prantesh Jain, Austin Steward, Jeanne M DeCara, Iredia M Olaye, Kathryn Hansen, Jim Logan, Carmen Bergom, Carri Glide-Hurst, Irving Loh, John Alan Gambril, James MacLeod, Ragasnehith Maddula, Peter J McGranaghan, Akshee Batra, Courtney Campbell, Abdulaziz Hamid, Fatma Gunturkun, Robert Davis, John Jefferies, Michael Fradley, Katherine Albert, Anne Blaes, Indrajit Choudhuri, Arjun K Ghosh, Thomas D Ryan, Ogochukwu Ezeoke, Douglas J Leedy, Wadsworth Williams, Sebastian Roman, Lorenz Lehmann, Abdullah Sarkar, Diego Sadler, Elizabeth Polter, Kathryn J Ruddy, Neha Bansal, Eric Yang, Brijesh Patel, David Cho, Alison Bailey, Daniel Addison, Vijay Rao, Joshua E Levenson, Dipti Itchhaporia, Karol Watson, Martha Gulati, Kim Williams, Donald Lloyd-Jones, Erin Michos, Julie Gralow, Hugo Martinez
As cancer therapies increase in effectiveness and patients' life expectancies improve, balancing oncologic efficacy while reducing acute and long-term cardiovascular toxicities has become of paramount importance. To address this pressing need, the Cardiology Oncology Innovation Network (COIN) was formed to bring together domain experts with the overarching goal of collaboratively investigating, applying, and educating widely on various forms of innovation to improve the quality of life and cardiovascular healthcare of patients undergoing and surviving cancer therapies...
February 2024: American heart journal plus: cardiology research and practice
#6
JOURNAL ARTICLE
Elise V Voltura, Donald J Brightsmith, Juan Cornejo, Ian Tizard, Christopher A Bailey, J Jill Heatley
Inappropriate diets cause many of the health problems commonly reported in parrots by psittaculturists and veterinarians. The dietary management of captive parrots would benefit from information derived from studies of dietary habits of wild parrots; however, it is unclear how complete this body of knowledge is at this time. Documentation of parrots' dietary habits appears to have grown dramatically over the past century. Reports of parrots consuming a number of foodstuffs beyond the reproductive parts of plants (alternate foodstuffs) have increased...
January 2024: Journal of Avian Medicine and Surgery
#7
JOURNAL ARTICLE
Shefali S Verma, Harini V Gudiseva, Venkata R M Chavali, Rebecca J Salowe, Yuki Bradford, Lindsay Guare, Anastasia Lucas, David W Collins, Vrathasha Vrathasha, Rohini M Nair, Sonika Rathi, Bingxin Zhao, Jie He, Roy Lee, Selam Zenebe-Gete, Anita S Bowman, Caitlin P McHugh, Michael C Zody, Maxwell Pistilli, Naira Khachatryan, Ebenezer Daniel, Windell Murphy, Jeffrey Henderer, Tyler G Kinzy, Sudha K Iyengar, Neal S Peachey, Kent D Taylor, Xiuqing Guo, Yii-Der Ida Chen, Linda Zangwill, Christopher Girkin, Radha Ayyagari, Jeffrey Liebmann, Chimd M Chuka-Okosa, Susan E Williams, Stephen Akafo, Donald L Budenz, Olusola O Olawoye, Michele Ramsay, Adeyinka Ashaye, Onoja M Akpa, Tin Aung, Janey L Wiggs, Ahmara G Ross, Qi N Cui, Victoria Addis, Amanda Lehman, Eydie Miller-Ellis, Prithvi S Sankar, Scott M Williams, Gui-Shuang Ying, Jessica Cooke Bailey, Jerome I Rotter, Robert Weinreb, Chiea Chuen Khor, Michael A Hauser, Marylyn D Ritchie, Joan M O'Brien
Primary open-angle glaucoma (POAG), the leading cause of irreversible blindness worldwide, disproportionately affects individuals of African ancestry. We conducted a genome-wide association study (GWAS) for POAG in 11,275 individuals of African ancestry (6,003 cases; 5,272 controls). We detected 46 risk loci associated with POAG at genome-wide significance. Replication and post-GWAS analyses, including functionally informed fine-mapping, multiple trait co-localization, and in silico validation, implicated two previously undescribed variants (rs1666698 mapping to DBF4P2; rs34957764 mapping to ROCK1P1) and one previously associated variant (rs11824032 mapping to ARHGEF12) as likely causal...
January 18, 2024: Cell
#8
JOURNAL ARTICLE
Ashley Leak Bryant, Rachel Hirschey, Courtney E Caiola, Ya-Ning Chan, Youngmin Cho, Brenda L Plassman, Bei Wu, Ruth A Anderson, Donald E Bailey
Oral health declines in older adults with cognitive impairment. We aimed to improve oral hygiene outcomes for individuals with mild cognitive impairment (MCI) or mild dementia (MD) by fostering behavior changes among carepartners assisting them. We used qualitative data of verbatim transcripts of coaching sessions with carepartners (n = 17 dyads:10 dyads for MCI, 7 dyads for MD). Directed and emergent coding were used to understand behavior change techniques (BCTs). BCTs were compared with carepartners of participants with MCI and MD...
January 17, 2024: Geriatric Nursing
#9
JOURNAL ARTICLE
Marta I Mulawa, Sharron L Docherty, Donald E Bailey, Rosa M Gonzalez-Guarda, Isaac M Lipkus, Schenita D Randolph, Qing Yang, Wei Pan
Systemic racism is pervasive in US society and disproportionately limits opportunities for education, work, and health for historically marginalized and minoritized racial and ethnic groups, making it an urgent issue of social justice. Because systemic racism is a social determinant of health prevalent across multiple social and institutional structures, it requires multilevel intervention approaches using effective designs and analytic methods to measure and evaluate outcomes. Racism is a fundamental cause of poor health outcomes, including mental health outcomes; thus, mental health services and programs that address racism and discrimination are key to promoting positive mental health of racial and ethnic minority youth...
January 4, 2024: Prevention Science: the Official Journal of the Society for Prevention Research
#10
JOURNAL ARTICLE
Joey Ward, Laura M Lyall, Breda Cullen, Rona J Strawbridge, Xingxing Zhu, Ioana Stanciu, Alisha Aman, Claire L Niedzwiedz, Jana Anderson, Mark E S Bailey, Donald M Lyall, Jill P Pell
Happiness is a fundamental human affective trait, but its biological basis is not well understood. Using a novel approach, we construct LDpred-inf polygenic scores of a general happiness measure in 2 cohorts: the Adolescent Brain Cognitive Development (ABCD) cohort (N = 15,924, age range 9.23-11.8 years), the Add Health cohort (N = 9129, age range 24.5-34.7) to determine associations with several well-being and happiness measures. Additionally, we investigated associations between genetic scores for happiness and brain structure in ABCD (N = 9626, age range (8...
October 12, 2023: Scientific Reports
#11
JOURNAL ARTICLE
Rachel S Goodman, J Randall Patrinely, Cosby A Stone, Eli Zimmerman, Rebecca R Donald, Sam S Chang, Sean T Berkowitz, Avni P Finn, Eiman Jahangir, Elizabeth A Scoville, Tyler S Reese, Debra L Friedman, Julie A Bastarache, Yuri F van der Heijden, Jordan J Wright, Fei Ye, Nicholas Carter, Matthew R Alexander, Jennifer H Choe, Cody A Chastain, John A Zic, Sara N Horst, Isik Turker, Rajiv Agarwal, Evan Osmundson, Kamran Idrees, Colleen M Kiernan, Chandrasekhar Padmanabhan, Christina E Bailey, Cameron E Schlegel, Lola B Chambless, Michael K Gibson, Travis J Osterman, Lee E Wheless, Douglas B Johnson
IMPORTANCE: Natural language processing tools, such as ChatGPT (generative pretrained transformer, hereafter referred to as chatbot), have the potential to radically enhance the accessibility of medical information for health professionals and patients. Assessing the safety and efficacy of these tools in answering physician-generated questions is critical to determining their suitability in clinical settings, facilitating complex decision-making, and optimizing health care efficiency...
October 2, 2023: JAMA Network Open
#12
JOURNAL ARTICLE
Rachana Trivedi, Bailey Knopf, Sharlene Rakoczy, Gunjan D Manocha, Holly Brown-Borg, Donald A Jurivich
Brain aging is a major risk factor for cognitive diseases such as Alzheimer's disease (AD) and vascular dementia. The rate of aging and age-related pathology are modulated by stress responses and repair pathways that gradually decline with age. However, recent reports indicate that exceptional longevity sustains and may even enhance the stress response. Whether normal and exceptional aging result in either attenuated or enhanced stress responses across all organs is unknown. This question arises from our understanding that biological age differs from chronological age and evidence that the rate of aging varies between organs...
September 14, 2023: Biogerontology
#13
COMMENT
Donald B Bailey
No abstract text is available yet for this article.
October 1, 2023: JAMA Pediatrics
#14
JOURNAL ARTICLE
Robyn K Wojeck, Mitchell R Knisely, Donald E Bailey, Tamara J Somers, Linda Kwakkenbos, Marie-Eve Carrier, Warren R Nielson, Susan J Bartlett, Vanessa L Malcarne, Marie Hudson, Brooke Levis, Andrea Benedetti, Luc Mouthon, Brett D Thombs, Susan G Silva
BACKGROUND: Systemic sclerosis is a heterogenous disease in which little is known about patterns of patient-reported symptom clusters. We aimed to identify classes of individuals with similar anxiety, depression, fatigue, sleep disturbance, and pain symptoms and to evaluate associated sociodemographic and disease-related characteristics. METHODS: This multi-centre cross-sectional study used baseline data from Scleroderma Patient-centered Intervention Network Cohort participants enrolled from 2014 to 2020...
August 2023: EClinicalMedicine
#15
JOURNAL ARTICLE
Ravi B Patel, Vivek Y Reddy, Jan Komtebedde, Stephan W Wegerich, Jadranka Sekaric, Vijay Swarup, Antony Walton, Gabriel Laurent, Stanley Chetcuti, Matthias Rademann, Martin Bergmann, Scott McKenzie, Heiko Bugger, Raphael Romano Bruno, Howard C Herrmann, Ajith Nair, Deepak K Gupta, Scott Lim, Samir Kapadia, Robert Gordon, Marc Vanderheyden, Thomas Noel, Steven Bailey, Zachary M Gertz, Jean-Noël Trochu, Donald E Cutlip, Martin B Leon, Scott D Solomon, Dirk J van Veldhuisen, Angelo Auricchio, Sanjiv J Shah
BACKGROUND: Atrial fibrillation (AF) is a common comorbidity in patients with heart failure with preserved ejection fraction (HFpEF) and in heart failure with mildly reduced ejection fraction (HFmrEF). OBJECTIVES: This study sought to describe AF burden and its clinical impact among individuals with HFpEF and HFmrEF who participated in a randomized clinical trial of atrial shunt therapy (REDUCE LAP-HF II [A Study to Evaluate the Corvia Medical, Inc IASD System II to Reduce Elevated Left Atrial Pressure in Patients with Heart Failure]) and to evaluate the effect of atrial shunt therapy on AF burden...
July 10, 2023: JACC. Heart Failure
#16
JOURNAL ARTICLE
Elias Samuels, Donald Vereen, Patricia Piechowski, Athena McKay, E Hill De Loney, Sarah Bailey, Luther Evans, Bettina Campbell, Yvonne Lewis, Ella Greene-Moton, Kent Key, DeWaun Robinson, Arlene Sparks, Ellen Champagne, Susan Woolford
BACKGROUND/OBJECTIVE: In 2017, the Michigan Institute for Clinical and Health Research (MICHR) and community partners in Flint, Michigan collaborated to launch a research funding program and evaluate the dynamics of those research partnerships receiving funding. While validated assessments for community-engaged research (CEnR) partnerships were available, the study team found none sufficiently relevant to conducting CEnR in the context of the work. MICHR faculty and staff along with community partners living and working in Flint used a community-based participatory research (CBPR) approach to develop and administer a locally relevant assessment of CEnR partnerships that were active in Flint in 2019 and 2021...
2023: Journal of Clinical and Translational Science
#17
JOURNAL ARTICLE
Elizabeth Reynolds, Sheresa Blanchard, Elizabeth Jalazo, Pranesh Chakraborty, Donald B Bailey
OBJECTIVES: The purpose of this study is to explore which newborn screening (NBS) conditions are automatically eligible for early intervention (EI) across states and to determine the extent to which each disorder should automatically qualify for EI because of a high probability of developmental delay. METHODS: We examined each state's EI eligibility policy and reviewed the literature documenting developmental outcomes for each NBS condition. Using a novel matrix, we assessed the risk of developmental delay, medical complexity, and risk of episodic decompensation, revising the matrix iteratively until reaching consensus...
June 2023: Journal of Developmental and Behavioral Pediatrics: JDBP
#18
JOURNAL ARTICLE
Breda Cullen, Marc J Gameroff, Joey Ward, Mark E S Bailey, Donald M Lyall, Laura M Lyall, Niamh MacSweeney, Eleanor Murphy, Natasha Sangha, Xueyi Shen, Rona J Strawbridge, Milenna T van Dijk, Xingxing Zhu, Daniel J Smith, Ardesheer Talati, Heather C Whalley, Jonathan Cavanagh, Myrna M Weissman
IMPORTANCE: Cognitive impairment in depression is poorly understood. Family history of depression is a potentially useful risk marker for cognitive impairment, facilitating early identification and targeted intervention in those at highest risk, even if they do not themselves have depression. Several research cohorts have emerged recently that enable findings to be compared according to varying depths of family history phenotyping, in some cases also with genetic data, across the life span...
June 1, 2023: JAMA Psychiatry
#19
JOURNAL ARTICLE
Bailey A Martin-Giacalone, Melissa A Richard, Michael E Scheurer, Javed Khan, Pagna Sok, Priya B Shetty, Stephen J Chanock, Shengchao Alfred Li, Meredith Yeager, Deborah A Marquez-Do, Donald A Barkauskas, David Hall, Matthew T McEvoy, Austin L Brown, Aniko Sabo, Paul Scheet, Chad D Huff, Stephen X Skapek, Douglas S Hawkins, Rajkumar Venkatramani, Lisa Mirabello, Philip J Lupo
BACKGROUND: Relative to other pediatric cancers, survival for rhabdomyosarcoma has not improved in recent decades, suggesting the need to enhance risk stratification. Therefore, we conducted a genome-wide association study for event-free survival (EFS) and overall survival (OS) to identify genetic variants associated with outcomes in individuals with rhabdomyosarcoma. METHODS: The study included 920 individuals with newly diagnosed rhabdomyosarcoma who were enrolled on Children's Oncology Group protocols...
March 23, 2023: Journal of the National Cancer Institute
#20
Douglas Johnson, Rachel Goodman, J Patrinely, Cosby Stone, Eli Zimmerman, Rebecca Donald, Sam Chang, Sean Berkowitz, Avni Finn, Eiman Jahangir, Elizabeth Scoville, Tyler Reese, Debra Friedman, Julie Bastarache, Yuri van der Heijden, Jordan Wright, Nicholas Carter, Matthew Alexander, Jennifer Choe, Cody Chastain, John Zic, Sara Horst, Isik Turker, Rajiv Agarwal, Evan Osmundson, Kamran Idrees, Colleen Kieman, Chandrasekhar Padmanabhan, Christina Bailey, Cameron Schlegel, Lola Chambless, Mike Gibson, Travis Osterman, Lee Wheless
BACKGROUND: Natural language processing models such as ChatGPT can generate text-based content and are poised to become a major information source in medicine and beyond. The accuracy and completeness of ChatGPT for medical queries is not known. METHODS: Thirty-three physicians across 17 specialties generated 284 medical questions that they subjectively classified as easy, medium, or hard with either binary (yes/no) or descriptive answers. The physicians then graded ChatGPT-generated answers to these questions for accuracy (6-point Likert scale; range 1 - completely incorrect to 6 - completely correct) and completeness (3-point Likert scale; range 1 - incomplete to 3 - complete plus additional context)...
February 28, 2023: Research Square
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