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https://www.readbyqxmd.com/read/28575260/social-support-social-strain-and-cognitive-function-among-community-dwelling-u-s-chinese-older-adults
#1
Shaoqing Ge, Bei Wu, Donald E Bailey, XinQi Dong
Background: Limited research is available on the relationship between social support, social strain, and cognitive function among community-dwelling U.S. Chinese older adults. This study aims to examine the associations between social support/strain and cognitive outcomes. Methods: Data were drawn from the Population-Based Study of Chinese Elderly (N = 3,159). Cognitive function was measured by a battery of tests including the East Boston Memory Test, the Digit Span Backwards assessment, and the Symbol Digit Modalities Test...
July 1, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28435479/a-novel-program-for-absn-students-to-generate-interest-in-geriatrics-and-geriatric-nursing-research
#2
Jennifer Mewshaw, Donald E Bailey, Amber L Anderson, Ruth A Anderson, Andrew L Burd, Cathleen Colón-Emeric, Kirsten N Corazzini
The current shortage of nurse researchers in geriatrics adversely affects the capacity of nurses to conduct research to advance the evidence-based care of older adults. In an effort to generate interest in geriatrics and geriatric nursing research, the Duke University School of Nursing designed a summer internship for four students enrolled in the accelerated baccalaureate nursing (ABSN) program. This paper describes the experience of these ABSN students and the staff and faculty who worked with them. The program design, staff and faculty experiences, benefits and challenges, as well as recommendations for future programs are discussed...
2017: Journal of Nursing Education and Practice
https://www.readbyqxmd.com/read/28362683/thrombin-generation-profiles-as-predictors-of-symptomatic-venous-thromboembolism-after-trauma-a-prospective-cohort-study
#3
Myung S Park, Grant M Spears, Kent R Bailey, Ailing Xue, Michael J Ferrara, Amy Headlee, Sabtir K Dhillon, Donald H Jenkins, Scott P Zietlow, William S Harmsen, Aneel A Ashrani, John A Heit
BACKGROUND: Reliable biomarkers predictive of venous thromboembolism (VTE) after acute trauma are uncertain. The objective of the study was to identify risk factors for symptomatic VTE after trauma, including individual plasma coagulome characteristics as reflected by thrombin generation. METHODS: In a prospective, case-cohort study, trauma patients were enrolled over the 4.5 year period, 2011-2015. Blood was collected by venipuncture into 3.2% trisodium citrate at 0, 6, 12, 24 and 72 hours after injury, and at hospital discharge...
March 30, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28277289/randomized-trial-of-an-uncertainty-self-management-telephone-intervention-for-patients-awaiting-liver-transplant
#4
Donald E Bailey, Cristina C Hendrix, Karen E Steinhauser, Karen M Stechuchak, Laura S Porter, Julie Hudson, Maren K Olsen, Andrew Muir, Sarah Lowman, Andrea DiMartini, Laurel Williams Salonen, James A Tulsky
OBJECTIVE: We tested an uncertainty self-management telephone intervention (SMI) with patients awaiting liver transplant and their caregivers. METHODS: Participants were recruited from four transplant centers and completed questionnaires at baseline, 10, and 12 weeks from baseline (generally two and four weeks after intervention delivery, respectively). Dyads were randomized to either SMI (n=56) or liver disease education (LDE; n=59), both of which involved six weekly telephone sessions...
March 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28251931/sleep-characteristics-modify-the-association-of-genetic-predisposition-with-obesity-and-anthropometric-measurements-in-119-679-uk-biobank-participants
#5
Carlos Celis-Morales, Donald M Lyall, Yibing Guo, Lewis Steell, Daniel Llanas, Joey Ward, Daniel F Mackay, Stephany M Biello, Mark Es Bailey, Jill P Pell, Jason Mr Gill
Background: Obesity is a multifactorial condition influenced by genetics, lifestyle, and environment.Objective: We investigated whether the association of a validated genetic profile risk score for obesity (GPRS-obesity) with body mass index (BMI) and waist circumference (WC) was modified by sleep characteristics.Design: This study included cross-sectional data from 119,859 white European adults, aged 37-73 y, participating in the UK Biobank. Interactions of GPRS-obesity and sleep characteristics (sleep duration, chronotype, day napping, and shift work) with their effects on BMI and WC were investigated...
April 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28237927/efficient-hardware-implementation-for-fingerprint-image-enhancement-using-anisotropic-gaussian-filter
#6
Tariq Mahmood Khan, Donald G Bailey, Mohammad A U Khan, Yinan Kong
A real-time image filtering technique is proposed which could result in faster implementation for fingerprint image enhancement. One major hurdle associated with fingerprint filtering techniques is the expensive nature of their hardware implementations. To circumvent this, a modified anisotropic Gaussian filter is efficiently adopted in hardware by decomposing the filter into two orthogonal Gaussians and an oriented line Gaussian. An architecture is developed for dynamically controlling the orientation of the line Gaussian filter...
May 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28231416/feasibility-of-combining-common-data-elements-across-studies-to-test-a-hypothesis
#7
Elizabeth J Corwin, Shirley M Moore, Andrea Plotsky, Margaret M Heitkemper, Susan G Dorsey, Drenna Waldrop-Valverde, Donald E Bailey, Sharron L Docherty, Joanne D Whitney, Carol M Musil, Cynthia M Dougherty, Donna J McCloskey, Joan K Austin, Patricia A Grady
PURPOSE: The purpose of this article is to describe the outcomes of a collaborative initiative to share data across five schools of nursing in order to evaluate the feasibility of collecting common data elements (CDEs) and developing a common data repository to test hypotheses of interest to nursing scientists. This initiative extended work already completed by the National Institute of Nursing Research CDE Working Group that successfully identified CDEs related to symptoms and self-management, with the goal of supporting more complex, reproducible, and patient-focused research...
May 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28096516/newborn-sequencing-in-genomic-medicine-and-public-health
#8
Jonathan S Berg, Pankaj B Agrawal, Donald B Bailey, Alan H Beggs, Steven E Brenner, Amy M Brower, Julie A Cakici, Ozge Ceyhan-Birsoy, Kee Chan, Flavia Chen, Robert J Currier, Dmitry Dukhovny, Robert C Green, Julie Harris-Wai, Ingrid A Holm, Brenda Iglesias, Galen Joseph, Stephen F Kingsmore, Barbara A Koenig, Pui-Yan Kwok, John Lantos, Steven J Leeder, Megan A Lewis, Amy L McGuire, Laura V Milko, Sean D Mooney, Richard B Parad, Stacey Pereira, Joshua Petrikin, Bradford C Powell, Cynthia M Powell, Jennifer M Puck, Heidi L Rehm, Neil Risch, Myra Roche, Joseph T Shieh, Narayanan Veeraraghavan, Michael S Watson, Laurel Willig, Timothy W Yu, Tiina Urv, Anastasia L Wise
The rapid development of genomic sequencing technologies has decreased the cost of genetic analysis to the extent that it seems plausible that genome-scale sequencing could have widespread availability in pediatric care. Genomic sequencing provides a powerful diagnostic modality for patients who manifest symptoms of monogenic disease and an opportunity to detect health conditions before their development. However, many technical, clinical, ethical, and societal challenges should be addressed before such technology is widely deployed in pediatric practice...
February 2017: Pediatrics
https://www.readbyqxmd.com/read/28030809/genomic-regulation-of-invasion-by-stat3-in-triple-negative-breast-cancer
#9
Joy M McDaniel, Katherine E Varley, Jason Gertz, Daniel S Savic, Brian S Roberts, Sarah K Bailey, Lalita A Shevde, Ryne C Ramaker, Brittany N Lasseigne, Marie K Kirby, Kimberly M Newberry, E Christopher Partridge, Angela L Jones, Braden Boone, Shawn E Levy, Patsy G Oliver, Katherine C Sexton, William E Grizzle, Andres Forero, Donald J Buchsbaum, Sara J Cooper, Richard M Myers
Breast cancer is a heterogeneous disease comprised of four molecular subtypes defined by whether the tumor-originating cells are luminal or basal epithelial cells. Breast cancers arising from the luminal mammary duct often express estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth receptor 2 (HER2). Tumors expressing ER and/or PR are treated with anti-hormonal therapies, while tumors overexpressing HER2 are targeted with monoclonal antibodies. Immunohistochemical detection of ER, PR, and HER2 receptors/proteins is a critical step in breast cancer diagnosis and guided treatment...
January 31, 2017: Oncotarget
https://www.readbyqxmd.com/read/28030499/the-coalition-for-national-trauma-research-cntr-supports-the-call-for-a-national-trauma-research-action-plan
#10
Raul Coimbra, Rosemary A Kozar, Jason W Smith, Ben L Zarzaur, Carl J Hauser, Frederick A Moore, Jeffrey A Bailey, Alex Valadka, Gregory J Jurkovich, Donald H Jenkins, Kimberly A Davis, Michelle A Price, Ronald V Maier
No abstract text is available yet for this article.
December 23, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28017591/a-dual-inhibitory-mechanism-sufficient-to-maintain-cell-cycle-restricted-cenp-a-assembly
#11
Ana Stankovic, Lucie Y Guo, João F Mata, Dani L Bodor, Xing-Jun Cao, Aaron O Bailey, Jeffrey Shabanowitz, Donald F Hunt, Benjamin A Garcia, Ben E Black, Lars E T Jansen
Chromatin featuring the H3 variant CENP-A at the centromere is critical for its mitotic function and epigenetic maintenance. Assembly of centromeric chromatin is restricted to G1 phase through inhibitory action of Cdk1/2 kinases in other phases of the cell cycle. Here, we identify the two key targets sufficient to maintain cell-cycle control of CENP-A assembly. We uncovered a single phosphorylation site in the licensing factor M18BP1 and a cyclin A binding site in the CENP-A chaperone, HJURP, that mediated specific inhibitory phosphorylation...
January 19, 2017: Molecular Cell
https://www.readbyqxmd.com/read/27913647/diversity-of-antiviral-igg-effector-activities-observed-in-hiv-infected-and-vaccinated-subjects
#12
Yunda Huang, Guido Ferrari, Galit Alter, Donald N Forthal, John C Kappes, George K Lewis, J Christopher Love, Bhavesh Borate, Linda Harris, Kelli Greene, Hongmei Gao, Tran B Phan, Gary Landucci, Brittany A Goods, Karen G Dowell, Hao D Cheng, Chris Bailey-Kellogg, David C Montefiori, Margaret E Ackerman
Diverse Ab effector functions mediated by the Fc domain have been commonly associated with reduced risk of infection in a growing number of nonhuman primate and human clinical studies. This study evaluated the anti-HIV Ab effector activities in polyclonal serum samples from HIV-infected donors, VAX004 vaccine recipients, and healthy HIV-negative subjects using a variety of primary and cell line-based assays, including Ab-dependent cellular cytotoxicity (ADCC), Ab-dependent cell-mediated viral inhibition, and Ab-dependent cellular phagocytosis...
December 15, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/27911419/methods-of-soil-resampling-to-monitor-changes-in-the-chemical-concentrations-of-forest-soils
#13
Gregory B Lawrence, Ivan J Fernandez, Paul W Hazlett, Scott W Bailey, Donald S Ross, Thomas R Villars, Angelica Quintana, Rock Ouimet, Michael R McHale, Chris E Johnson, Russell D Briggs, Robert A Colter, Jason Siemion, Olivia L Bartlett, Olga Vargas, Michael R Antidormi, Mary M Koppers
Recent soils research has shown that important chemical soil characteristics can change in less than a decade, often the result of broad environmental changes. Repeated sampling to monitor these changes in forest soils is a relatively new practice that is not well documented in the literature and has only recently been broadly embraced by the scientific community. The objective of this protocol is therefore to synthesize the latest information on methods of soil resampling in a format that can be used to design and implement a soil monitoring program...
November 25, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27822316/developmental-profiles-of-infants-with-an-fmr1-premutation
#14
Anne C Wheeler, John Sideris, Randi Hagerman, Elizabeth Berry-Kravis, Flora Tassone, Donald B Bailey
BACKGROUND: Emerging evidence suggests that a subset of FMR1 premutation carriers is at an increased risk for cognitive, emotional, and medical conditions. However, because the premutation is rarely diagnosed at birth, the early developmental trajectories of children with a premutation are not known. METHODS: This exploratory study examined the cognitive, communication, and social-behavioral profiles of 26 infants with a premutation who were identified through participation in a newborn screening for fragile X syndrome pilot study...
2016: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/27768656/origins-and-importance-of-the-joint-trauma-system
#15
Donald H Jenkins, Jeffrey A Bailey
No abstract text is available yet for this article.
November 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27760082/age-at-natural-menopause-genetic-risk-score-in-relation-to-age-at-natural-menopause-and-primary-open-angle-glaucoma-in-a-us-based-sample
#16
Louis R Pasquale, Hugues Aschard, Jae H Kang, Jessica N Cooke Bailey, Sara Lindström, Daniel I Chasman, William G Christen, R Rand Allingham, Allison Ashley-Koch, Richard K Lee, Sayoko E Moroi, Murray H Brilliant, Gadi Wollstein, Joel S Schuman, John Fingert, Donald L Budenz, Tony Realini, Terry Gaasterland, Douglas Gaasterland, William K Scott, Kuldev Singh, Arthur J Sit, Robert P Igo, Yeunjoo E Song, Lisa Hark, Robert Ritch, Douglas J Rhee, Vikas Gulati, Shane Havens, Douglas Vollrath, Donald J Zack, Felipe Medeiros, Robert N Weinreb, Margaret A Pericak-Vance, Yutao Liu, Peter Kraft, Julia E Richards, Bernard A Rosner, Michael A Hauser, Jonathan L Haines, Janey L Wiggs
OBJECTIVE: Several attributes of female reproductive history, including age at natural menopause (ANM), have been related to primary open-angle glaucoma (POAG). We assembled 18 previously reported common genetic variants that predict ANM to determine their association with ANM or POAG. METHODS: Using data from the Nurses' Health Study (7,143 women), we validated the ANM weighted genetic risk score in relation to self-reported ANM. Subsequently, to assess the relation with POAG, we used data from 2,160 female POAG cases and 29,110 controls in the National Eye Institute Glaucoma Human Genetics Collaboration Heritable Overall Operational Database (NEIGHBORHOOD), which consists of 8 datasets with imputed genotypes to 5...
February 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27711066/corrigendum-adjuvant-dependent-innate-and-adaptive-immune-signatures-of-risk-of-sivmac251-acquisition
#17
Monica Vaccari, Shari N Gordon, Slim Fourati, Luca Schifanella, Namal P M Liyanage, Mark Cameron, Brandon F Keele, Xiaoying Shen, Georgia D Tomaras, Erik Billings, Mangala Rao, Amy W Chung, Karen G Dowell, Chris Bailey-Kellogg, Eric P Brown, Margaret E Ackerman, Diego A Vargas-Inchaustegui, Stephen Whitney, Melvin N Doster, Nicolo Binello, Poonam Pegu, David C Montefiori, Kathryn Foulds, David S Quinn, Mitzi Donaldson, Frank Liang, Karin Loré, Mario Roederer, Richard A Koup, Adrian McDermott, Zhong-Min Ma, Christopher J Miller, Tran B Phan, Donald N Forthal, Matthew Blackburn, Francesca Caccuri, Massimiliano Bissa, Guido Ferrari, Vaniambadi Kalyanaraman, Maria G Ferrari, DeVon Thompson, Marjorie Robert-Guroff, Silvia Ratto-Kim, Jerome H Kim, Nelson L Michael, Sanjay Phogat, Susan W Barnett, Jim Tartaglia, David Venzon, Donald M Stablein, Galit Alter, Rafick-Pierre Sekaly, Genoveffa Franchini
No abstract text is available yet for this article.
October 6, 2016: Nature Medicine
https://www.readbyqxmd.com/read/27692491/patient-and-family-communication-during-consultation-visits-the-effects-of-a-decision-aid-for-treatment-decision-making-for-localized-prostate-cancer
#18
Lixin Song, Christina Tyler, Margaret F Clayton, Eleanor Rodgiriguez-Rassi, Latorya Hill, Jinbing Bai, Raj Pruthi, Donald E Bailey
OBJECTIVE: To analyze the effects of a decision aid on improving patients' and family members' information giving and question asking during consultations for prostate cancer treatment decision-making. METHODS: This study is a secondary analysis of archived audio-recorded real-time consultation visits with participants from a randomized clinical trial. Participants were randomly assigned into three groups: TD-intervention targeted patient-only; TS-intervention targeted patients and family members; and control-a handout on staying healthy during treatment...
February 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/27661856/assessing-the-association-of-mitochondrial-genetic-variation-with-primary-open-angle-glaucoma-using-gene-set-analyses
#19
Anthony P Khawaja, Jessica N Cooke Bailey, Jae Hee Kang, R Rand Allingham, Michael A Hauser, Murray Brilliant, Donald L Budenz, William G Christen, John Fingert, Douglas Gaasterland, Terry Gaasterland, Peter Kraft, Richard K Lee, Paul R Lichter, Yutao Liu, Felipe Medeiros, Syoko E Moroi, Julia E Richards, Tony Realini, Robert Ritch, Joel S Schuman, William K Scott, Kuldev Singh, Arthur J Sit, Douglas Vollrath, Gadi Wollstein, Donald J Zack, Kang Zhang, Margaret Pericak-Vance, Robert N Weinreb, Jonathan L Haines, Louis R Pasquale, Janey L Wiggs
Purpose: Recent studies indicate that mitochondrial proteins may contribute to the pathogenesis of primary open-angle glaucoma (POAG). In this study, we examined the association between POAG and common variations in gene-encoding mitochondrial proteins. Methods: We examined genetic data from 3430 POAG cases and 3108 controls derived from the combination of the GLAUGEN and NEIGHBOR studies. We constructed biological-system coherent mitochondrial nuclear-encoded protein gene-sets by intersecting the MitoCarta database with the Kyoto Encyclopedia of Genes and Genomes (KEGG) database...
September 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27537254/a-common-variant-in-mir182-is-associated-with-primary-open-angle-glaucoma-in-the-neighborhood-consortium
#20
MULTICENTER STUDY
Yutao Liu, Jessica Cooke Bailey, Inas Helwa, W Michael Dismuke, Jingwen Cai, Michelle Drewry, Murray H Brilliant, Donald L Budenz, William G Christen, Daniel I Chasman, John H Fingert, Douglas Gaasterland, Terry Gaasterland, Mae O Gordon, Robert P Igo, Jae H Kang, Michael A Kass, Peter Kraft, Richard K Lee, Paul Lichter, Sayoko E Moroi, Anthony Realini, Julia E Richards, Robert Ritch, Joel S Schuman, William K Scott, Kuldev Singh, Arthur J Sit, Yeunjoo E Song, Douglas Vollrath, Robert Weinreb, Felipe Medeiros, Gadi Wollstein, Donald J Zack, Kang Zhang, Margaret A Pericak-Vance, Pedro Gonzalez, W Daniel Stamer, John Kuchtey, Rachel W Kuchtey, R Rand Allingham, Michael A Hauser, Louis R Pasquale, Jonathan L Haines, Janey L Wiggs
PURPOSE: Noncoding microRNAs (miRNAs) have been implicated in the pathogenesis of glaucoma. We aimed to identify common variants in miRNA coding genes (MIR) associated with primary open-angle glaucoma (POAG). METHODS: Using the NEIGHBORHOOD data set (3853 cases/33,480 controls with European ancestry), we first assessed the relation between 85 variants in 76 MIR genes and overall POAG. Subtype-specific analyses were performed in high-tension glaucoma (HTG) and normal-tension glaucoma subsets...
August 1, 2016: Investigative Ophthalmology & Visual Science
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