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https://www.readbyqxmd.com/read/28549078/herod-a-human-ethnic-and-regional-specific-omics-database
#1
Xian Zeng, Lin Tao, Zhang Peng, Chu Qin, Shangying Chen, Weidong He, Ying Tan, Hong Xia Liu, Sheng Yong Yang, Zhe Chen, Yu Yang Jiang, Yu Zong Chen
Motivation: Genetic and gene expression variations within and between populations and across geographical regions have substantial effects on the biological phenotypes, diseases, and therapeutic response. The development of precision medicines can be facilitated by the OMICS studies of the patients of specific ethnicity and geographic region. However, there is an inadequate facility for broadly and conveniently accessing the ethnic and regional specific OMICS data. Results: Here, we introduced a new free database, HEROD, a human ethnic and regional specific OMICS database...
May 26, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28543608/evaluation-of-a-state-based-syndromic-surveillance-system-for-the-classification-and-capture-of-non-fatal-occupational-injuries-and-illnesses-in-new-jersey
#2
Marija Borjan, Margaret Lumia
BACKGROUND: This preliminary study evaluates a real-time syndromic surveillance system to track occupationally-related emergency room visits throughout New Jersey. METHODS: Emergency Department (ED) chief complaint fields were evaluated from 79 of 80 hospitals in NJ in 2014, using work-related keywords and ICD-9 E-codes, to determine its ability to capture non-fatal work-related injuries. Sensitivity analysis and descriptive statistics, were used to evaluate and summarize the occupational injuries identified...
May 23, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28532226/novel-biological-therapies-for-the-treatment-of-diabetic-foot-ulcers
#3
Jennifer Adeghate, Syed Nurulain, Kornélia Tekes, Erzsébet Fehér, Huba Kalász, Ernest Adeghate
The number of people with diabetes mellitus (DM) is estimated to exceed 640 million by the year 2040. Diabetic foot ulcer (DFU) is a debilitating illness that affects more than 2% of DM patients. DFU is caused by DM-induced neural and vascular lesions leading to a reduced sensation and microcirculation. The increase in the prevalence of DFU has prompted researchers to find new therapies for the management of DFU. Areas covered: This review presents the current status of novel biological therapies used in the treatment of DFU...
May 22, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28530617/-principles-of-urinary-tract-reconstructive-surgery
#4
Juan Gomez Rivas, Jesús Cisneros Ledo
INTRODUCTION: In the last 15 years, the role of laparoscopic surgery has progressively increased to include reconstructive procedures such as pyeloplasty and management of ureteral stricture, in addition to being a field in continuous development, this refers to the improvement of ergonomics, new instruments and new techniques. We present a review on basic features of laparoscopic reconstructive surgery in urology. ACQUISITION OF EVIDENCE: For this review, an exhaustive literature search was performed in PUBMED, MEDILNE, BioMed central and others, with the keywords: reconstructive surgery, urology, laparoscopy...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28527153/the-rise-of-phenology-with-climate-change-an-evaluation-of-ijb-publications
#5
Alison Donnelly, Rong Yu
In recent decades, phenology has become an important tool by which to measure both the impact of climate change on ecosystems and the feedback of ecosystems to the climate system. However, there has been little attempt to date to systematically quantify the increase in the number of scientific publications with a focus on phenology and climate change. In order to partially address this issue, we examined the number of articles (original papers, reviews and short communications) containing the terms 'phenology' and 'climate change' in the title, abstract or keywords, published in the International Journal of Biometeorology in the 60 years since its inception in 1957...
May 19, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28516751/growth-hormone-therapy-and-brain-tumors
#6
Akira Teramoto
As one of the projects of the Adverse Events Study Group of the Foundation for Growth Science in Japan, the literatures on the recurrence and / or regrowth or new formation of brain tumors in patients treated with growth hormone (GH) were reviewed. Since the tumor volume of the sellar lesion can be accurately evaluated only by magnetic resonance imaging (MRI), the related literatures published after 1990 were retrieved by searching under keywords, such as GH, replacement therapy, brain tumor, recurrence, tumor formation, etc...
March 2017: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28509730/american-college-of-critical-care-medicine-clinical-practice-parameters-for-hemodynamic-support-of-pediatric-and-neonatal-septic-shock
#7
Alan L Davis, Joseph A Carcillo, Rajesh K Aneja, Andreas J Deymann, John C Lin, Trung C Nguyen, Regina S Okhuysen-Cawley, Monica S Relvas, Ranna A Rozenfeld, Peter W Skippen, Bonnie J Stojadinovic, Eric A Williams, Tim S Yeh, Fran Balamuth, Joe Brierley, Allan R de Caen, Ira M Cheifetz, Karen Choong, Edward Conway, Timothy Cornell, Allan Doctor, Marc-Andre Dugas, Jonathan D Feldman, Julie C Fitzgerald, Heidi R Flori, James D Fortenberry, Ana Lia Graciano, Bruce M Greenwald, Mark W Hall, Yong Yun Han, Lynn J Hernan, Jose E Irazuzta, Elizabeth Iselin, Elise W van der Jagt, Howard E Jeffries, Saraswati Kache, Chhavi Katyal, Niranjan Tex Kissoon, Alexander A Kon, Martha C Kutko, Graeme MacLaren, Timothy Maul, Renuka Mehta, Fola Odetola, Kristine Parbuoni, Raina Paul, Mark J Peters, Suchitra Ranjit, Karin E Reuter-Rice, Eduardo J Schnitzler, Halden F Scott, Adalberto Torres, Jacki Weingarten-Abrams, Scott L Weiss, Jerry J Zimmerman, Aaron L Zuckerberg
OBJECTIVES: The American College of Critical Care Medicine provided 2002 and 2007 guidelines for hemodynamic support of newborn and pediatric septic shock. Provide the 2014 update of the 2007 American College of Critical Care Medicine "Clinical Guidelines for Hemodynamic Support of Neonates and Children with Septic Shock." DESIGN: Society of Critical Care Medicine members were identified from general solicitation at Society of Critical Care Medicine Educational and Scientific Symposia (2006-2014)...
June 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28508813/web-and-mobile-based-hiv-prevention-and-intervention-programs-pros-and-cons-a-review
#8
Sharareh Niakan, Esmaeil Mehraeen, Tayebeh Noori, Elahe Gozali
BACKGROUND: With the increasing growth of HIV positive people the use of information and communication technologies (ICT) can play an important role in controlling the spread of the AIDS. Web and Mobile are the new technologies that young people take advantage from them. OBJECTIVES: In this study a review to investigate the web and mobile based HIV prevention and intervention programs was carried out. METHODS: A scoping review was conducted including PubMed, Science direct, Web of Science and Proquest to find relevant sources that published in 2009 to 2016...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28507765/asthma-epidemiology-of-disease-control-in-latin-america-short-review
#9
REVIEW
Dirceu Solé, Carolina Sanchez Aranda, Gustavo Falbo Wandalsen
Asthma is reported as one of the most common chronic diseases in childhood, impairing the quality of life of patients and their families and incurring high costs to the healthcare system and society. Despite the development of new drugs and the availability of international treatment guidelines, asthma is still poorly controlled, especially in Latin America. Original and review articles on asthma control or epidemiology with high levels of evidence have been selected for analysis among those published in PubMed referenced journals during the last 20 years, using the following keywords: "asthma control" combined with "Latin America", " epidemiology", "prevalence", "burden", "mortality", "treatment and unmet needs", "children", "adolescents", and "infants"...
2017: Asthma research and practice
https://www.readbyqxmd.com/read/28494034/efficacy-of-local-and-systemic-statin-delivery-on-the-osseointegration-of-implants-a-systematic-review
#10
Sergio Varela Kellesarian, Mohammad D Al Amri, Abdulaziz A Al-Kheraif, Alexis Ghanem, Hans Malmstrom, Fawad Javed
PURPOSE: In indexed literature, a systematic review of the efficacy of statins in enhancing osseointegration is lacking. The aim of this systematic review was to assess the efficacy of local and systemic statin delivery on the osseointegration of implants. MATERIALS AND METHODS: To address the focused question, "Does local and systemic statin delivery affect osseointegration around implants?", indexed databases were searched from 1965 through November 2015 using various keywords...
May 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28490220/solithromycin-cem-101-a-new-fluoroketolide-antibiotic-and-its-role-in-the-treatment-of-gonorrhea
#11
Alexandra M Mancuso, Mona A Gandhi, Judianne Slish
Solithromycin is a macrolide antibiotic that has undergone review for the treatment of community-acquired bacterial pneumonia. Solithromycin is also being investigated and has shown promise for the treatment of gonorrhea. With increasing antibiotic resistance, the development of novel antibiotics to combat infections is essential. The unique ribosome-binding stability of solithromycin and mild side effect profile make this a promising new antibiotic. This article will provide an overview on the mechanism of action, clinical efficacy, and safety of this drug for the treatment of gonorrhea...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28480103/cavernous-sinus-syndrome-as-the-first-manifestation-of-metastatic-breast-disease
#12
N B Seixas, T A B Belsuzarri, N C B Belsuzarri, M Pozetti, J F M Araujo
BACKGROUND: The cavernous sinus is a venous plexus crossed by vital neurovascular structures. Metastases to the region are uncommon and often associated with a headache, facial pain, or progressive neurological deficit in III, IV, and VI cranial nerves. The treatment options are surgery, including endoscopic approach, radiotherapy, radiosurgery, and chemotherapy. CASE DESCRIPTION: We report the case of a 26-year-old female with cavernous sinus syndrome due to breast cancer metastasis, who was subjected to chemotherapy with complete neurological recovery...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28479858/study-of-acupuncture-for-low-back-pain-in-recent-20-years-a-bibliometric-analysis-via-citespace
#13
Yu-Dan Liang, Ying Li, Jian Zhao, Xiao-Yin Wang, Hui-Zheng Zhu, Xiu-Hua Chen
BACKGROUND: Acupuncture has been applied to relieve low back pain (LBP) in many countries. However, a bibliometric analysis of the global use of acupuncture for LBP is rare. OBJECTIVE: The aim of this study was to demonstrate the state of the art and trends concerning the global use of acupuncture for LBP in recent 20 years. METHODS: Literature relating to acupuncture for LBP from 1997 to 2016 was retrieved from Web of Science. CiteSpace was used to analyze country/institution, cited journals, authors/cited authors, cited references, and keywords...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28479237/adjuvant-therapy-for-high-risk-localized-kidney-cancer-emerging-evidence-and-future-clinical-trials
#14
REVIEW
Andrew T Lenis, Nicholas M Donin, David C Johnson, Izak Faiena, Amirali Salmasi, Alexandra Drakaki, Arie Belldegrun, Allan Pantuck, Karim Chamie
PURPOSE: We will review the literature on adjuvant therapies for patients with high-risk localized kidney cancer following surgical treatment. Two recently published prospective trials with conflicting results will be reconciled within the context of their respective designs. Finally, we will spotlight upcoming trials that use novel immunotherapy-based checkpoint inhibitors and have the potential to establish a new standard of care. MATERIALS AND METHODS: A PubMed search was performed for English language articles using the keywords "renal cell carcinoma," "kidney cancer," "immunotherapy," "targeted therapy," and "adjuvant therapy" published through January 2017...
May 4, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28472397/olelo-a-web-application-for-intuitive-exploration-of-biomedical-literature
#15
Milena Kraus, Julian Niedermeier, Marcel Jankrift, Sören Tietböhl, Toni Stachewicz, Hendrik Folkerts, Matthias Uflacker, Mariana Neves
Researchers usually query the large biomedical literature in PubMed via keywords, logical operators and filters, none of which is very intuitive. Question answering systems are an alternative to keyword searches. They allow questions in natural language as input and results reflect the given type of question, such as short answers and summaries. Few of those systems are available online but they experience drawbacks in terms of long response times and they support a limited amount of question and result types...
May 3, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28465869/cutaneous-metastasis-from-tonsillar-squamous-cell-carcinoma-report-and-review-of-the-literature
#16
Omar Bari, Philip R Cohen
Tonsillar squamous cell carcinoma, which represents 10% of head and neck malignancies, rarely manifests with cutaneous metastases; to date, only three prior patients with tonsillar squamous cell carcinoma have been reported to develop cutaneous metastases. We describe the clinical features of a 59-year-old man with squamous cell carcinoma of the tonsil who developed cutaneous metastases within his prior radiation port and review the literature of prior patients with cutaneous metastases from tonsillar squamous cell carcinoma...
March 28, 2017: Curēus
https://www.readbyqxmd.com/read/28465868/red-dot-basal-cell-carcinoma-report-of-cases-and-review-of-this-unique-presentation-of-basal-cell-carcinoma
#17
Philip R Cohen
Red dot basal cell carcinoma is a unique variant of basal cell carcinoma. Including the three patients described in this report, red dot basal cell carcinoma has only been described in seven individuals. This paper describes the features of two males and one female with red dot basal cell carcinoma and reviews the characteristics of other patients with this clinical subtype of basal cell carcinoma. A 70-year-old male developed a pearly-colored papule with a red dot in the center on his nasal tip. A 71-year-old male developed a red dot surrounded by a flesh-colored papule on his left nostril...
March 22, 2017: Curēus
https://www.readbyqxmd.com/read/28445550/classifying-patents-based-on-their-semantic-content
#18
Antonin Bergeaud, Yoann Potiron, Juste Raimbault
In this paper, we extend some usual techniques of classification resulting from a large-scale data-mining and network approach. This new technology, which in particular is designed to be suitable to big data, is used to construct an open consolidated database from raw data on 4 million patents taken from the US patent office from 1976 onward. To build the pattern network, not only do we look at each patent title, but we also examine their full abstract and extract the relevant keywords accordingly. We refer to this classification as semantic approach in contrast with the more common technological approach which consists in taking the topology when considering US Patent office technological classes...
2017: PloS One
https://www.readbyqxmd.com/read/28438331/-the-intestinal-microbiota-a-new-player-in-depression
#19
M Meyrel, L Varin, B Detaint, F Mouaffak
Depression is the leading cause of disability in the world according to the World Health Organization. The effectiveness of the available antidepressant therapies is limited. Data from the literature suggest that some subtypes of depression may be associated with chronic low grade inflammation. The uncovering of the role of intestinal microbiota in the development of the immune system and its bidirectional communication with the brain have led to growing interest on reciprocal interactions between inflammation, microbiota and depression...
April 21, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28435812/scientometrics-on-public-health-research-in-iran-increase-of-area-studies-despite-embargoes-a-review-article
#20
REVIEW
Brice Poreau
BACKGROUND: Due to embargoes and sanctions from 1979 until 2015, impact on scientific research in Iran may be critical. Public health is the main example of this burning point. In this paper, the aim was to map the scientific research in public health in Iran until 2014 with area studies as well as networks of countries involved. METHODS: We used bibliographic analyses using VOS viewer software for network analysis during the period 1975-2014. Two databases were used: Web of Science and PubMed...
March 2017: Iranian Journal of Public Health
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