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Graue Enrique

Juan Carlos Serna-Ojeda, Denise Loya-Garcia, Alejandro Navas, Alejandro Lichtinger, Arturo Ramirez-Miranda, Enrique O Graue-Hernandez
PURPOSE: To analyze the characteristics and long-term outcomes of patients that underwent pediatric penetrating keratoplasty (PPK) for herpes simplex virus (HSV) keratitis. DESIGN: Retrospective, interventional, consecutive case series. METHODS: Observational report of outcomes and findings. Nine patients with history of HSV keratitis that underwent PPK and were followed in a single institution. Difference between the median preoperative and final best-corrected visual acuity (BCVA) was assessed and the outcomes are reported...
October 13, 2016: American Journal of Ophthalmology
Jaffer M Kattan, Juan Carlos Serna-Ojeda, Anushree Sharma, Eung K Kim, Arturo Ramirez-Miranda, Marisa Cruz-Aguilar, Aleck E Cervantes, Ricardo F Frausto, Juan Carlos Zenteno, Enrique O Graue-Hernandez, Anthony J Aldave
PURPOSE: To describe 2 unrelated families with multiple members demonstrating a less commonly recognized vortex pattern of corneal deposits confirmed to be granular corneal dystrophy type 1 (GCD1) after identification of the p.(Arg555Trp) mutation in the transforming growth factor β-induced gene (TGFBI). METHODS: A slit-lamp examination was performed on individuals from 2 families, one of Mexican descent and a second of Italian descent. After DNA extraction from affected individuals and their unaffected relatives, TGFBI screening was performed...
October 12, 2016: Cornea
Lorena Romero-Diaz-de-Leon, Juan Carlos Serna-Ojeda, Alejandro Navas, Enrique O Graue-Hernández, Arturo Ramirez-Miranda
PURPOSE: To report the rate of flap-related complications in LASIK surgery performed by in-training ophthalmology residents and to analyze the risk factors for these complications. METHODS: We analyzed 273 flap dissections in 145 patients from March 2013 to February 2014. We included all LASIK surgeries performed by 32 ophthalmology residents using a Moria M2 microkeratome. All the flap-related complications were noted. Comparison between both groups with and without complications was performed with an independent Student's t-test and relative risks were calculated...
July 2016: Journal of Ophthalmic & Vision Research
Denise Loya-Garcia, Juan Carlos Serna-Ojeda, Lucero Pedro-Aguilar, Aida Jimenez-Corona, Andrew Olivo-Payne, Enrique O Graue-Hernandez
PURPOSE: To report aetiology, characteristics, treatment and main outcomes of non-traumatic corneal perforations in a single referral centre. METHODS: A retrospective review of clinical records of patients diagnosed with non-traumatic corneal perforation. The analysed data included demographic characteristics, medical history, initial and final corrected distance visual acuity (CDVA), perforation aetiology, size, location, initial therapy, surgical treatment, ocular integrity and complications...
August 8, 2016: British Journal of Ophthalmology
Alexandra Abdala-Figuerola, Alejandro Navas, Arturo Ramirez-Miranda, Alejandro Lichtinger, Erick Hernandez-Bogantes, Andrew Olivo-Payne, Jesus Cabral-Macias, Enrique O Graue-Hernández
PURPOSE: To report a case series of 7 eyes of 6 patients with posterior keratoconus, evaluating corneal Scheimpflug tomographic changes and anterior-segment optical coherence tomography (OCT). METHODS: In our descriptive study, 6 patients were diagnosed with posterior keratoconus: 5 unilateral (7-, 33-, and 42-year-old males and 64- and 60-year-old female) and 1 bilateral (45-year-old female). Patients were diagnosed with slit-lamp examination, which revealed corneal opacity with an underlying posterior corneal depression...
October 2016: Cornea
Erick Hernandez-Bogantes, Juan Carlos Serna-Ojeda, Alejandro Lichtinger, Enrique O Graue-Hernández
No abstract text is available yet for this article.
May 2016: Indian Journal of Ophthalmology
Juan Carlos Serna-Ojeda, Enrique Ariza-Camacho, Alberto Collado-Solórzano, Blanca C Flores-Sánchez, Abelardo A Rodríguez-Reyes, Emiliano Fulda-Graue
The adenoma of the nonpigmented ciliary epithelium is a benign rare tumor, which may present with different clinical characteristics and requires resection along with histopathologic analysis and the identification of specific immunohistochemical markers for an accurate diagnosis. Here, we report a case series of 4 patients in a Mexican mestizo population with this diagnosis, their clinical features, the ultrasound imaging characteristics and the histopathological and immunohistochemical findings.
June 2015: Ocular Oncology and Pathology
Jesus Cabral-Macias, Juan C Zenteno, Arturo Ramirez-Miranda, Alejandro Navas, Jose A Bermudez-Magner, Víctor M Boullosa-Graña, Enrique O Graue-Hernandez, Beatriz Buentello-Volante
PURPOSE: To describe the clinical findings and results of molecular analysis in a Mexican family diagnosed with gelatinous drop-like corneal dystrophy (GDLD). METHODS: Ophthalmological examination was performed in 1 unaffected and 4 affected relatives. Molecular analysis included polymerase chain reaction amplification and direct nucleotide sequencing of the entire TACSTD2 gene-coding region in genomic DNA. RESULTS: The corneal phenotype in adult patients was characterized by white-yellow nodular lesions on the corneal surface and stromal neovascularization...
July 2016: Cornea
Jayesh Vazirani, Mohammed Hasnat Ali, Namrata Sharma, Nidhi Gupta, Vikas Mittal, Marwan Atallah, Guillermo Amescua, Tuhin Chowdhury, Alexandra Abdala-Figuerola, Arturo Ramirez-Miranda, Alejandro Navas, Enrique O Graue-Hernández, James Chodosh
PURPOSE: To report outcomes of autologous simple limbal epithelial transplantation (SLET) performed for unilateral limbal stem cell deficiency (LSCD) at multiple centres worldwide. METHODS: In this retrospective, multicentre, interventional case series, records of patients who had undergone autologous SLET for unilateral LSCD, with a minimum of 6 months of follow-up, were reviewed. The primary outcome measure was clinical success, defined as a completely epithelised, avascular corneal surface...
October 2016: British Journal of Ophthalmology
Enrique O Graue Hernandez, Erick Hernandez-Bogantes
No abstract text is available yet for this article.
December 2015: Journal of Cataract and Refractive Surgery
Patricia Chirinos-Saldaña, Alejandro Navas, Arturo Ramírez-Miranda, María Carmen Jiménez-Martínez, Enrique O Graue-Hernández
OBJECTIVE: To describe the epidemiology, etiology, pathogenesis, clinical characteristics, and management of pemphigus, with an emphasis on ocular involvement. METHODS: Literature review. RESULTS: Pemphigus is an autoimmune epithelial blistering disease of the skin and mucous membranes. The typical pathological finding is acantholysis of the epidermis that leads to blister formation. Immunofluorescence techniques show autoantibody deposition on the epidermal intercellular substance...
March 2016: Eye & Contact Lens
Juan Carlos Serna-Ojeda, Arturo Ramirez-Miranda, Alejandro Navas, Aida Jimenez-Corona, Enrique O Graue-Hernandez
PURPOSE: To analyze the clinical presentation, characteristics, treatment, recurrences, and final outcomes and complications of herpes simplex virus (HSV) disease of the anterior segment in patients aged 17 years or younger. METHODS: This is an observational and retrospective study with review of the medical records of all the children diagnosed with herpes simplex infection of the anterior segment at an ophthalmologic referral center, from 2002 to 2012. The diagnosis was made on the basis of the history and examination of patients and in specific cases by viral culture and the polymerase chain reaction...
October 2015: Cornea
Arturo Ramirez-Miranda, Tito Ramirez-Luquin, Alejandro Navas, Enrique O Graue-Hernandez
PURPOSE: To report the complications associated with refractive lenticule extraction (ReLEx) in its 2 modalities: femtosecond lenticule extraction (FLEx) and small incision lenticule extraction (SMILE). METHODS: In this retrospective review of a consecutive clinical case series, all patients who had a complicated ReLex FLEx or ReLEx SMILE procedure at the Cornea and External Disease Department at the Instituto de Oftalmologia Fundacion Conde de Valenciana, Mexico City, Mexico, were included...
October 2015: Cornea
Lucero Pedro-Aguilar, Arturo Ramirez-Miranda, Victor M Bautista-de Lucio, Alejandro Navas, Mariana Ortiz-Casas, Enrique O Graue-Hernandez
OBJECTIVE: To determine the characteristics of infectious keratitis caused by Kocuria spp. METHODS: Retrospective case series. Information included demographic data, medical history, risk factors associated with infectious keratitis, clinical characteristics, microbiological results and drug sensitivity, clinical course, management, and visual outcomes. RESULTS: Eight patients were included (7 females and 1 male; mean age, 66.2 years; age range, 42-84 years)...
September 2016: Eye & Contact Lens
Rodrigo Bolaños-Jiménez, Alejandro Navas, Erika Paulina López-Lizárraga, Francesc March de Ribot, Alexandra Peña, Enrique O Graue-Hernández, Yonathan Garfias
Sight is one of the most important senses that human beings possess. The ocular system is a complex structure equipped with mechanisms that prevent or limit damage caused by physical, chemical, infectious and environmental factors. These mechanisms include a series of anatomical, cellular and humoral factors that have been a matter of study. The cornea is not only the most powerful and important lens of the optical system, but also, it has been involved in many other physiological and pathological processes apart from its refractive nature; the morphological and histological properties of the cornea have been thoroughly studied for the last fifty years; drawing attention in its molecular characteristics of immune response...
2015: Open Ophthalmology Journal
Erick Hernández-Bogantes, Guillermo Amescua, Alejandro Navas, Yonathan Garfias, Arturo Ramirez-Miranda, Alejandro Lichtinger, Enrique O Graue-Hernández
We describe a novel surgical technique for pterygium removal taking advantage of the properties of amniotic membrane and limbal epithelial stem cells. A total of 10 eyes underwent pterygium excision with amniotic membrane coverage of the bare sclera and placement of pieces of limbal epithelium in a linear fashion in the affected limbal area covered by a second amniotic membrane using fibrin glue. After up to 8 months of follow-up, there were no signs of early recurrence or sight-threatening complications...
December 2015: British Journal of Ophthalmology
Julio C Hernandez-Camarena, Enrique O Graue-Hernandez, Mariana Ortiz-Casas, Arturo Ramirez-Miranda, Alejandro Navas, Lucero Pedro-Aguilar, Nadia L Lopez-Espinosa, Carolina Gaona-Juarez, Luis A Bautista-Hernandez, Victor M Bautista-de Lucio
PURPOSE: To report the distribution and trends in microbiological and antibiotic sensitivity patterns of infectious keratitis in a 10-year period at a reference center in Mexico City. METHODS: In this retrospective observational case series, samples were obtained from corneas with a diagnosis of infectious keratitis from January 2002 to December 2011 at the Institute of Ophthalmology "Conde de Valenciana" in Mexico City. Results of cultures, stains, and specific sensitivity/resistance antibiograms for each microorganism were analyzed...
July 2015: Cornea
Alexandra Abdala Figuerola, Enrique O Graue-Hernández
No abstract text is available yet for this article.
December 2014: Journal of Cataract and Refractive Surgery
Julio C Hernández-Camarena, Patricia Chirinos-Saldaña, Alejandro Navas, Arturo Ramirez-Miranda, Angle de la Mota, Aida Jimenez-Corona, Enrique O Graue-Hernindez
PURPOSE: To assess the reliability of three different Scheimpflug systems and their agreement. METHODS: Eighty-four eyes of 42 patients were examined with three Scheimpflug devices: the Galilei G2 Dual Scheimpflug Analyzer (Ziemer Ophthalmic Systems AG, Port, Switzerland), Pentacam HR system (Oculus Optikgerate GmbH, Wetzlar, Germany), and Sirius 3D imaging system (Costruzione Strumenti Oftalmici, Florence, Italy). The central corneal thickness, maximum anterior and posterior corneal elevation, anterior radius of curvature, total higher-order aberrations, and anterior chamber depth were evaluated...
September 2014: Journal of Refractive Surgery
Aida Jimenez-Corona, Maria E Jimenez-Corona, Samuel Ponce-de-Leon, Mariela Chavez-Rodriguez, Enrique O Graue-Hernandez
PURPOSE: Visual impairment in disadvantaged populations in Mexico has been scarcely reported. We compared the prevalence of visual impairment and its associated risk factors in populations in rural compared to urban areas of the Mexican southern state of Chiapas. METHODS: In a population-based study, the prevalence of visual impairment in rural and urban areas of Comitan, Chiapas, was estimated. All eligible individuals aged ≥20 years living in rural areas were invited to participate; persons from urban areas were chosen randomly...
2015: Ophthalmic Epidemiology
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