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https://www.readbyqxmd.com/read/28330322/de-novo-transcriptome-sequencing-in-monsonia-burkeana-revealed-putative-genes-for-key-metabolic-pathways-involved-in-tea-quality-and-medicinal-value
#1
Adugna A Woldesemayat, Khayalethu Ntushelo, David M Modise
Monsonia (Monsonia burkeana Planch. ex Harv) is one of the most valuable tea and traditional medicinal plants used in Southern Africa. In spite of this, there is no sequence information regarding this plant in literature. To provide understanding of the naturally occurring tea and drug-specific products and the key pathways for the biosynthesis of these molecules, we sequenced the leaf transcriptome using Illumina MiSeq platform and generated 2,590,652 paired-end reads that were assembled de novo into 45,450 high-quality transcripts...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28329867/effectiveness-of-a-virtual-reality-forest-on-people-with-dementia-a-mixed-methods-pilot-study
#2
Wendy Moyle, Cindy Jones, Toni Dwan, Tanya Petrovich
Purpose of the Study: To measure and describe the effectiveness of a Virtual Reality Forest (VRF) on engagement, apathy, and mood states of people with dementia, and explore the experiences of staff, people with dementia and their families. Design and Methods: A mixed-methods study conducted between February and May 2016. Ten residents with dementia, 10 family members, and 9 care staff were recruited from 2 residential aged care facilities, operated by one care provider, located in Victoria, Australia...
March 15, 2017: Gerontologist
https://www.readbyqxmd.com/read/28329822/it-s-all-about-the-relationship-cognitively-intact-mother-daughter-care-dyads-in-hospice-at-home
#3
Diane N Solomon, Lissi Hansen, Judith G Baggs
Purpose of the Study: Adult daughters providing care to aging, ill mothers comprise the most prevalent caregiving dyad. Little is known, however, regarding relationship quality and its impact on care in these dyads, particularly in the context of cognitively intact patients at end of life in hospice. This interpretive descriptive work privileges voices of terminally ill mothers and care-partnering daughters in the home hospice context. Specific aims were to describe and interpret how mothers and daughters: (a) perceive relationship quality and (b) perceive how relationships have developed over time through health, chronic illness, and hospice...
March 10, 2017: Gerontologist
https://www.readbyqxmd.com/read/28329807/are-you-sleeping-dyadic-associations-of-support-stress-and-worries-regarding-adult-children-on-sleep
#4
Amber J Seidel, Jeremy B Yorgason, Courtney A Polenick, Steven H Zarit, Karen L Fingerman
Purpose of the study: Sleep is a key factor in maintaining positive health and well-being throughout life. Although the negative outcomes of sleep problems are becoming better understood, less is known about how intergenerational relationships might affect sleep. Thus, this investigation examines the dyadic associations of support for, stress over, and worrying about adult children on sleep quality for husbands and wives. Design and Methods: The sample included 186 heterosexual married couples drawn from the Family Exchanges Study...
January 24, 2017: Gerontologist
https://www.readbyqxmd.com/read/28329340/baseline-characteristics-of-participants-in-the-aspree-aspirin-in-reducing-events-in-the-elderly-study
#5
John J McNeil, Robyn L Woods, Mark R Nelson, Anne M Murray, Christopher M Reid, Brenda Kirpach, Elsdon Storey, Raj C Shah, Rory S Wolfe, Andrew M Tonkin, Anne B Newman, Jeff D Williamson, Jessica E Lockery, Karen L Margolis, Michael E Ernst, Walter P Abhayaratna, Nigel Stocks, Sharyn M Fitzgerald, Ruth E Trevaks, Suzanne G Orchard, Lawrence J Beilin, Geoffrey A Donnan, Peter Gibbs, Colin I Johnston, Richard H Grimm
Background: There are no primary prevention trials of aspirin with relevant geriatric outcomes in elderly people. ASPirin in Reducing Events in the Elderly (ASPREE) is a placebo-controlled trial of low-dose aspirin that will determine whether 5 years of daily 100-mg enteric-coated aspirin extends disability-free and dementia-free life in a healthy elderly population and whether these benefits outweigh the risks. Methods: Set in primary care, this randomized double-blind placebo-controlled trial has a composite primary endpoint of death, incident dementia or persistent physical disability...
January 20, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28327507/variation-in-older-adult-characteristics-by-residence-type-and-use-of-home-and-community-based-services
#6
Heidi H Ewen, Tiffany R Washington, Kerstin G Emerson, Andrew T Carswell, Matthew Lee Smith
Background: The majority of older adults prefer to remain in their homes, or to "age-in-place." To accomplish this goal, many older adults will rely upon home- and community-based services (HCBS) for support. However, the availability and accessibility of HCBS may differ based on whether the older adult lives in the community or in a senior housing apartment facility. Methods: This paper reports findings from the Pathways to Life Quality study of residential change and stability among seniors in upstate New York...
March 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28327492/pet-therapy-an-effective-strategy-to-care-for-the-elderly-an-experimental-study-in-a-nursing-home
#7
Alfonso Sollami, Elisa Gianferrari, Manuela Alfieri, Giovanna Artioli, Chiara Taffurelli
BACKGROUND AND AIM: There has recently been a growing interest towards patients' affective and emotional needs, especially in relational therapies, which are considered vital as to increase the understanding of those needs and patients' well-being. In particular, we paid attention to those patients who are forced to spend the last phase of their existence in residential facilities, namely elderly people in nursing homes, who often feel marginalized, useless, depressed, unstimulated or unable to communicate...
March 14, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28324266/quality-of-life-in-patients-with-recurrent-breast-cancer-after-second-breast-conserving-therapy-in-comparison-with-mastectomy-the-german-experience
#8
Svenja Jendrian, Katharina Steffens, Barbara Schmalfeldt, Elena Laakmann, Corinna Bergelt, Isabell Witzel
BACKGROUND: Although some studies suggest that breast-conserving therapy (BCT) shows better psychosocial outcomes than mastectomy in patients with primary breast cancer, little is known about the outcomes of these surgical options in recurrent breast cancer. We investigated differences in overall survival and re-recurrence rates as well as psychosocial outcomes among patients who underwent BCT or mastectomy after the diagnosis of recurrent breast cancer in a single-center setting. METHODS: 124 of 186 eligible patients who underwent surgical treatment for breast cancer recurrence completed the questionnaires on quality of life (EORTC QLQ-C30 and -BR23), fear of progression (PA-F-KF), anxiety and depression (HADS), and body image (BIS)...
March 21, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28322074/speaking-a-different-language
#9
Anne G Ciriello, Zoelle B Dizon, Tessie W October
BACKGROUND: Family conferences in the pediatric intensive care unit (ICU) often include palliative care (PC) providers. We do not know how ICU communication differs when the PC team is present. AIM: To compare language used by PC team and ICU physicians during family conferences. DESIGN: A retrospective cohort review of ICU family conferences with and without the PC team. SETTING: Forty-four bed pediatric ICU in a tertiary medical center...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/28321962/psychosocial-care-for-children-with-haemophilia-and-their-parents-in-the-netherlands
#10
REVIEW
P F Limperg, L Haverman, M Beijlevelt, M van der Pot, G Zaal, W A de Boer, K Fijnvandraat, M Peters, M A Grootenhuis
INTRODUCTION: Children growing up with haemophilia are at greater risk for psychosocial problems than their healthy peers. Providing psychosocial care to children with haemophilia and their families is indispensable, since psychosocial factors can have a significant impact on health and health-related quality of life (HRQOL). AIMS: Our aim was to give a description of psychosocial care provided by the multidisciplinary team of the Hemophilia Comprehensive Care Centre (HCCC) at the Emma Children's Hospital in Amsterdam, the Netherlands...
March 21, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28320454/mitigation-of-disease-and-treatment-related-risks-in-patients-with-psoriatic-arthritis
#11
REVIEW
Martin Bergman, Amy Lundholm
Psoriatic arthritis is a part of the family of diseases referred to as spondyloarthropathies, a diverse group of chronic inflammatory disorders with common clinical, radiographic, and genetic features. Peripheral arthritis is the most common symptom of psoriatic arthritis and patients also frequently experience involvement of the entheses, spine, skin, and nails. Due to the diverse clinical spectrum of disease severity, tissues affected, and associated comorbidities, the treatment of psoriatic arthritis can be challenging and it is necessary to mitigate risks associated with both the disease and its treatment...
March 20, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28320146/stroke-related-stigma-among-west-africans-patterns-and-predictors
#12
Fred Stephen Sarfo, Michelle Nichols, Suparna Qanungo, Abeba Teklehaimanot, Arti Singh, Nathaniel Mensah, Raelle Saulson, Mulugeta Gebregziabher, Uvere Ezinne, Mayowa Owolabi, Carolyn Jenkins, Bruce Ovbiagele
BACKGROUND: Disability-adjusted life-years lost after stroke in Low & Middle-Income Countries (LMICs) is almost seven times those lost in High-income countries. Although individuals living with chronic neurological and mental disorders are prone to stigma, there is a striking paucity of literature on stroke-related stigma particularly from LMICs. OBJECTIVE: To assess the prevalence, severity, determinants and psycho-social consequences of stigma among LMIC stroke survivors...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28319263/a-review-of-family-caregiving-intervention-trials-in-oncology
#13
REVIEW
Betty Ferrell, Elaine Wittenberg
This article contains a review of literature published from 2010 to 2016 on family caregiving in oncology. An analysis of 810 citations resulted in 50 randomized trials. These trials describe the need to prepare family caregivers for the complex role they play in cancer care. Several studies have demonstrated improved quality of life for family caregivers and improved emotional support from interventions. Several studies addressed communication and relational intimacy, which are key concerns. An additional focus of these trials was in the area of caregiving tasks and ways to diminish the burden of caregiving and preparedness for this role...
March 20, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28318431/the-pursuit-of-romantic-alternatives-online-social-media-friends-as-potential-romantic-alternatives
#14
Irum Saeed Abbasi, Nawal G Alghamdi
What causes some marriages to stand the test of time while others fail? Marital commitment is the key force underlying the stability, quality, and longevity of the romantic relationship. Commitment is strengthened in the presence of marital satisfaction, the absence of alternative attractions, and steady investments made in the relationship. Commitment is also a consequence of increasing dependence such that when partners are emotionally engaged with their virtual connections, their dependence on their significant other weakens resulting in low commitment...
March 20, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28316220/-correlation-between-social-support-and-quality-of-life-in-patients-with-breast-cancer-at-different-periods-of-treatment
#15
L Yang, W P Song, Z L Chen, Y Wang, Y Y Chen, Y H Hua, M Chen, W B Zou
Objective: To analyze the differences between the social support for breast cancer patients and healthy female, and to explore the correlation between social support and quality of life (QOL) in the patients. Methods: From January 2013 to December 2014, 101 patients with operable breast cancer treated at Xinyu City People's Hospital were recruited as the experimental group. They completed questionnaires in the preoperative, postoperative chemoradiotherapy and rehabilitation periods, respectively.101 healthy female volunteers recruited from the community were included as control group, whose age and level of education were matched with those of the experimental group...
March 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28316177/-efficacy-and-safety-of-tertiary-hospital-guided-and-community-driven-family-self-help-cardiac-rehabilitation-model
#16
R J Ding, L M Gao, L Chu, W L Xie, X R Wang, Q Tang, H L Wang, D Y Hu
Objective: To explore the efficacy and safety of tertiary hospital guided and community-driven family self-help cardiac rehabilitation model. Methods: This study was a prospective randomized controlled study, 80 patients from Beijing Electrical Power Hospital and Beijing Jingmei Group General Hospital with acute coronary syndrome were included from June to December 2015 and divided into 2 groups. Patients in rehabilitation group (n=52) received tertiary hospital(Peiking University Peoples' Hospital) guided and community-driven family self-help cardiac rehabilitation for 3 months, and patients in control group (n=28) received routine secondary treatment for 3 months...
March 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28314725/a-genome-survey-and-postharvest-transcriptome-analysis-in-lentinula-edodes
#17
Yuichi Sakamoto, Keiko Nakade, Shiho Sato, Kentaro Yoshida, Kazuhiro Miyazaki, Satoshi Natsume, Naotake Konno
Lentinula edodes is a popular cultivated edible and medicinal mushroom. Lentinula edodes is susceptible to postharvest problems such as gill browning, fruiting body softening, and lentinan degradation. We constructed a de novo assembly draft genome sequence and performed gene prediction of Lentinula edodesDe novo assembly was carried out using short reads from paired-end and mate-paired libraries and long reads by PacBio, resulting in a contig number of 1951 and an N50 of 1 Mb. Further, we predicted genes by Augustus using RNA-seq data from the whole life cycle of Lentinula edodes, resulting in 12,959 predicted genes...
March 17, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28314228/untreated-perinatal-paternal-depression-effects-on-offspring
#18
REVIEW
Salvatore Gentile, Maria Luigia Fusco
Transition to parenthood represents an important life event which increases vulnerability to psychological disorders. Aim of this article is to analyze all studies which investigated the effects of untreated perinatal paternal depression in offspring. We searched pertinent, peer-reviewed articles published in English (January 1980 to April 2016) on MEDLINE, PsycINFO, and Science.gov. Twenty-three studies met the inclusion criteria. Most of the reviewed studies suffer from methodological limitations, including the small sample, the lack of a structured psychiatric diagnosis, and inclusion bias...
March 2, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28306169/economic-burden-of-relapsed-or-refractory-multiple-myeloma-results-from-an-international-trial
#19
Don Robinson, Robert Z Orlowski, Michael Stokes, Jianming He, Samuel Huse, Abhishek Chitnis, Britte Kranenburg, Annette Lam
OBJECTIVE: The direct cost of relapsed or refractory multiple myeloma (RRMM) is documented; indirect costs are being explored. Healthcare payers seek cost offsets from therapies that improve clinical outcomes but challenge budgets; employers seek lower absenteeism and better productivity. Study goals were to: 1) Identify direct and indirect economic factors of RRMM and, 2) Explore longitudinal relationships between clinical, economic, and health-related quality of life (HRQoL) assessments...
March 17, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/28302101/preventing-diabetes-in-obese-latino-youth-with-prediabetes-a-study-protocol-for-a-randomized-controlled-trial
#20
Erica G Soltero, Yolanda P Konopken, Micah L Olson, Colleen S Keller, Felipe G Castro, Allison N Williams, Donald L Patrick, Stephanie Ayers, Houchun H Hu, Matthew Sandoval, Janiel Pimentel, William C Knowler, Kevin D Frick, Gabriel Q Shaibi
BACKGROUND: Obese Latino adolescents are disproportionately impacted by insulin resistance and type 2 diabetes. Prediabetes is an intermediate stage in the pathogenesis of type 2 diabetes and represents a critical opportunity for intervention. However, to date, no diabetes prevention studies have been conducted in obese Latino youth with prediabetes, a highly vulnerable and underserved group. Therefore, we propose a randomized-controlled trial to test the short-term (6-month) and long-term (12-month) efficacy of a culturally-grounded, lifestyle intervention, as compared to usual care, for improving glucose tolerance and reducing diabetes risk in 120 obese Latino adolescents with prediabetes...
March 16, 2017: BMC Public Health
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