keyword
MENU ▼
Read by QxMD icon Read
search

sensory modulation

keyword
https://www.readbyqxmd.com/read/28228721/patients-with-chronic-spinal-cord-injury-exhibit-reduced-autonomic-modulation-during-an-emotion-recognition-task
#1
Gonzalo Varas-Díaz, Enzo P Brunetti, Gonzalo Rivera-Lillo, Pedro E Maldonado
Spinal cord injury (SCI) is a devastating event for individuals, who frequently develop motor and sensory impairment as well as autonomic dysfunction. Previous studies reported that autonomic activity plays a major role in social cognition and that difficulties in the ability to interpret social information are commonly observed in a variety of mental disorders, which in turn correlate with a poor autonomic nervous system (ANS) regulation. It is well established that subjects with SCI have an alteration in ANS regulation mechanisms...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28228583/food-responsiveness-regulates-episodic-behavioral-states-in-caenorhabditis-elegans
#2
Richard J McCloskey, Anthony D Fouad, Matthew A Churgin, Christopher Fang-Yen
Animals optimize survival and reproduction in part through control of behavioral states, which depend on the organism's internal and external environments. In the nematode C. elegans, a variety of behavioral states have been described, including roaming, dwelling, quiescence, and episodic swimming. These states have been considered in isolation, under varied experimental conditions, making it difficult to establish a unified picture of how they are regulated. Using long-term imaging, we examined C. elegans episodic behavioral states under varied mechanical and nutritional environments...
February 22, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28227747/split-belt-adaptation-and-gait-symmetry-in-transtibial-amputees-walking-with-a-hybrid-emg-controlled-ankle-foot-prosthesis
#3
Oliver A Kannape, Hugh M Herr, Oliver A Kannape, Hugh M Herr, Oliver A Kannape, Hugh M Herr
Our ability to automatically adapt our walking pattern to the demands of our environment is central to maintaining a steady gait. Accordingly, a large effort is being made to extend and integrate this adaptability to lower-limb prostheses. To date, the main focus of this research has been on short term adaptation, such as in response to a terrain transition or a sudden change in the environment. However, long term adaptation and underlying sensorimotor learning processes are critical to optimizing walking patterns and predictively changing our gait when faced with continued perturbations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227740/influence-of-force-feedback-on-grasp-force-modulation-in-prosthetic-applications-a-preliminary-study
#4
Sasha B Godfrey, Matteo Bianchi, Antonio Bicchi, Marco Santello, Sasha B Godfrey, Matteo Bianchi, Antonio Bicchi, Marco Santello, Marco Santello, Antonio Bicchi, Sasha B Godfrey, Matteo Bianchi
In typical movement, humans use a combination of feed-forward and feedback motor control strategies to interact with the world around them. However, when sensory input is impaired or absent, as in the case of various neuropathies or amputation, the ability to perform everyday tasks, like modulating grip force to object weight, can be affected. In this study, we show the results of a preliminary study using a pressure cuff-like force feedback device (CUFF) with the SoftHand Pro (SHP) prosthetic hand. Subjects lifted an object of various weights using their own hand, with the SHP without feedback, and the SHP with force feedback...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227180/electrical-stimulation-of-the-saphenous-nerve-in-anesthetized-rats-a-novel-therapeutic-approach-to-treating-overactive-bladder
#5
Zainab Moazzam, Paul B Yoo, Zainab Moazzam, Paul B Yoo, Paul B Yoo, Zainab Moazzam
Posterior Tibial Nerve Stimulation (PTNS) is a minimally invasive yet effective therapy for treating overactive bladder (OAB) symptoms with electrical stimulations applied at 20 Hz coupled with amplitudes approximating the foot-twitch threshold (T). However, pre-clinical studies indicate that PTNS-evoked bladder reflexes require stimulation amplitudes exceeding 2T. The objective of this work was to evaluate the presence of secondary low-threshold sensory pathways in the hind-limb region that can be a potential target of activation during clinical PTNS set-up...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225715/the-role-of-cgrp-in-peripheral-and-central-pain-mechanisms-including-migraine
#6
Smriti Iyengar, Michael H Ossipov, Kirk W Johnson
Calcitonin gene-related peptide (CGRP) is a 37-amino acid peptide found primarily in the C and Aδ sensory fibers arising from the dorsal root and trigeminal ganglia, as well as the central nervous system. CGRP was found to play important roles in cardiovascular, digestive, and sensory functions. Although the vasodilatory properties of CGRP are well documented, its somatosensory function regarding modulation of neuronal sensitization and of enhanced pain has received considerable attention recently. Growing evidence indicates that CGRP plays a key role in the development of peripheral sensitization and the associated enhanced pain...
December 29, 2016: Pain
https://www.readbyqxmd.com/read/28223719/hepatitis-c-virus-associated-pruritus-etiopathogenesis-and-therapeutic-strategies
#7
EDITORIAL
Youssef Alhmada, Denis Selimovic, Fadi Murad, Sarah-Lilly Hassan, Youssef Haikel, Mossaad Megahed, Matthias Hannig, Mohamed Hassan
In addition to its contributing role in the development of chronic liver diseases, chronic hepatitis C virus (HCV) infection is associated with extrahepatic manifestations, particularly, cutaneous-based disorders including those with pruritus as a symptom. Pruritus is frequently associated with the development of chronic liver diseases such as cholestasis and chronic viral infection, and the accumulation of bile acids in patients' sera and tissues as a consequence of liver damage is considered the main cause of pruritus...
February 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28223362/mechanistic-insights-into-the-allosteric-regulation-of-bacterial-adp-glucose-pyrophosphorylases
#8
Natalia Comino, Javier Cifuente, Alberto Marina, Ane Orrantia, Ander Eguskiza, Marcelo E Guerin
ADP-glucose pyrophosphorylase (AGPase) controls bacterial glycogen and plant starch biosynthetic pathways, the most common carbon storage polysaccharides in nature. AGPase activity is allosterically regulated by a series of metabolites in the energetic flux within the cell. Very recently, we reported the first crystal structures of the paradigmatic AGPase from Escherichia coli (EcAGPase) in complex with its preferred physiological negative and positive allosteric regulators, adenosine-5'-monophosphate (AMP) and fructose-1,6-bisphosphate (FBP), respectively...
February 21, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28222563/afferent-electrical-stimulation-during-cycling-improves-spinal-processing-of-sensorimotor-function-after-incomplete-spinal-cord-injury
#9
Stefano Piazza, Diego Serrano-Muñoz, Julio Gómez-Soriano, Diego Torricelli, Antonio Segura-Fragosa, José Luis Pons, Julian Taylor
OBJECTIVE: Appropriate afferent feedback delivery during the execution of motor tasks is important for rehabilitation after incomplete spinal cord injury (iSCI). However, during leg-cycling therapy, the plantar afferent feedback is minimal. We hypothesize that the augmentation of sensory input by combining cycling with a locomotor-like stimulation of plantar cutaneous innervations (ES-cycling), might help to restore proper spinal processing of sensorimotor function. METHODS: 13 non-injured subjects and 10 subjects with iSCI performed 10 minutes of cycling and, on another session, of ES-cycling...
February 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222543/anodal-cerebellar-tdcs-modulates-lower-extremity-pain-perception
#10
Manuel Pereira, Basil Rafiq, Einul Chowdhury, Jacqueline Babayev, HyunJi Boo, Rowan Metwaly, Sandilya Priam, Eileen Chusid, Fortunato Battaglia
BACKGROUND: Previous studies have investigated the use of transcranial direct current stimulation (tDCS) for pain management. The studies investigating therapeutic neuromodulation with tDCS for lower extremity pain are scarce and inconclusive. OBJECTIVE: The aim of the present study was to analyze the effects of cerebellar tDCS on lower extremity sensory and pain thresholds in healthy volunteers. METHODS: This was a single-blind crossover repeated-measure study...
January 31, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222526/the-impact-of-alzheimer-s-disease-on-the-resting-state-functional-connectivity-of-brain-regions-modulating-pain-a-cross-sectional-study
#11
Todd B Monroe, Paul A Beach, Stephen P Bruehl, Mary S Dietrich, Baxter P Rogers, John C Gore, Sebastian W Atalla, Ronald L Cowan
BACKGROUND: It is currently unknown why people with Alzheimer's disease (AD) receive less pain medication and report pain less frequently. OBJECTIVE: The purpose of this study was to determine the impact of AD on thermal psychophysics and resting-state functional connectivity (RSFC) among sensory, affective, descending modulatory, and default mode structures. METHODS: Controls (n = 23, 13 = female) and age-matched people with AD (n = 23, 13 = females) underwent psychophysical testing to rate perceptions of warmth, mild, and moderate pain and then completed resting-state fMRI...
February 7, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28219951/generation-of-thalamic-neurons-from-mouse-embryonic-stem-cells
#12
Atsushi Shiraishi, Keiko Muguruma, Yoshiki Sasai
Thalamus is a diencephalic structure that plays crucial roles in relaying and modulating sensory and motor information to the neocortex. The thalamus develops in the dorsal part of the neural tube at the level of the caudal forebrain. However, the molecular mechanisms that are essential for thalamic differentiation are still unknown. Here we have succeeded in the generation of thalamic neurons from mouse ES cells (mESCs) by modifying the default method that induces the most-anterior neural type in self-organizing culture...
February 20, 2017: Development
https://www.readbyqxmd.com/read/28219675/tcf7l2-plays-crucial-roles-in-forebrain-development-through-regulation-of-thalamic-and-habenular-neuron-identity-and-connectivity
#13
Myungsin Lee, Jiyeon Yoon, Hobeom Song, Bumwhee Lee, Lam Tri Duc, Jaeseung Yoon, Kwanghee Baek, Hans Clevers, Yongsu Jeong
The thalamus acts as a central integrator for processing and relaying sensory and motor information to and from the cerebral cortex, and the habenula plays pivotal roles in emotive decision making by modulating dopaminergic and serotonergic circuits. These neural compartments are derived from a common developmental progenitor domain, called prosomere 2, in the caudal forebrain. Thalamic and habenular neurons exhibit distinct molecular profile, neurochemical identity, and axonal circuitry. However, the mechanisms of how their progenitors in prosomere 2 give rise to these two populations of neurons and contribute to the forebrain circuitry remains unclear...
February 17, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28218587/child-s-sensory-profile-and-adult-playfulness-as-predictors-of-parental-self-efficacy
#14
Rosa Román-Oyola, Stacey Reynolds, Ivonnellys Soto-Feliciano, Laura Cabrera-Mercader, Jessica Vega-Santana
Parents of children with autism spectrum disorder (ASD) may have difficulty engaging their children through play, thus affecting the parent-child relationship and parental self-efficacy. This study intended to examine children's sensory profile and adults' playfulness as predictors of parental self-efficacy. A total of 136 parents of children ages 3-7 yr completed the Short Sensory Profile, the Playfulness Scale for Adults, and the Tool to Measure Parenting Self-Efficacy. For the parental couples of children with ASD, the most relevant predictor of general parental self-efficacy was the child's sensory profile...
March 2017: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/28218303/a-combination-of-mutational-and-computational-scanning-guides-the-design-of-an-artificial-ligand-binding-controlled-lipase
#15
Marco Kaschner, Oliver Schillinger, Timo Fettweiss, Christina Nutschel, Frank Krause, Alexander Fulton, Birgit Strodel, Andreas Stadler, Karl-Erich Jaeger, Ulrich Krauss
Allostery, i.e. the control of enzyme activity by a small molecule at a location distant from the enzyme's active site, represents a mechanism essential for sustaining life. The rational design of allostery is a non-trivial task but can be achieved by fusion of a sensory domain, which responds to environmental stimuli with a change in its structure. Hereby, the site of domain fusion is difficult to predict. We here explore the possibility to rationally engineer allostery into the naturally not allosterically regulated Bacillus subtilis lipase A, by fusion of the citrate-binding sensor-domain of the CitA sensory-kinase of Klebsiella pneumoniae...
February 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28217893/geniculohypothalamic-gabaergic-projections-gate-suprachiasmatic-nucleus-responses-to-retinal-input
#16
Lydia Hanna, Lauren Walmsley, Abigail Pienaar, Michael Howarth, Timothy M Brown
Sensory input to the master mammalian circadian clock, the suprachiasmatic nucleus (SCN), is vital in allowing animals to optimise physiology and behaviour alongside daily changes in the environment. Retinal inputs encoding changes in external illumination provide the principle source of such information. The SCN also receives input from other retinorecipient brain regions, primarily via the geniculohypothalamic tract (GHT), but the contribution of these indirect projections to circadian photoreception are currently poorly understood...
February 20, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28215622/on-the-neural-basis-of-sensory-weighting-alpha-beta-and-gamma-modulations-during-complex-movements
#17
Nicolas Lebar, Jérémy Danna, Simon Moré, Laurence Mouchnino, Jean Blouin
Previous studies have revealed that visual and somatosensory information is processed as a function of its relevance during movement execution. We thus performed spectral decompositions of ongoing neural activities within the somatosensory and visual areas while human participants performed a complex visuomotor task. In this task, participants followed the outline of irregular polygons with a pen-controlled cursor. At unpredictable times, the motion of the cursor deviated 120° with respect to the actual pen position creating an incongruence between visual and somatosensory inputs, thus increasing the importance of visual feedback to control the movement as suggested in previous studies...
February 16, 2017: NeuroImage
https://www.readbyqxmd.com/read/28215304/neurotrophins-and-migraine
#18
L B Martins, A L Teixeira, R B Domingues
Neurotrophins (NTs) have been implicated in generation and modulation of nociceptive pathways. Change in NTs levels is associated with painful conditions and neurological diseases such as migraine. Currently, it is generally recognized that migraine headaches result from the activation and sensitization of trigeminal sensory afferent fibers leading to neuropeptides release such as calcitonin gene-related peptide (CGRP) and substance P (SP). This triggers an inflammatory cascade causing a neurogenic inflammation...
2017: Vitamins and Hormones
https://www.readbyqxmd.com/read/28215282/how-does-experience-shape-early-development-considering-the-role-of-top-down-mechanisms
#19
L L Emberson
Perceptual development requires infants to adapt their perceptual systems to the structures and statistical information of their environment. In this way, perceptual development is not only important in its own right, but is a case study for behavioral and neural plasticity-powerful mechanisms that have the potential to support developmental change in numerous domains starting early in life. While it is widely assumed that perceptual development is a bottom-up process, where simple exposure to sensory input modifies perceptual representations starting early in the perceptual system, there are several critical phenomena in this literature that cannot be explained with an exclusively bottom-up model...
2017: Advances in Child Development and Behavior
https://www.readbyqxmd.com/read/28215259/reduced-afferent-induced-facilitation-of-primary-motor-cortex-excitability-in-restless-legs-syndrome
#20
P Bocquillon, C Charley-Monaca, E Houdayer, A Marques, A Kwiatkowski, P Derambure, H Devanne
Restless legs syndrome (RLS) is characterized by the association of an urge to move, and vesperal or nocturnal sensory symptoms; it is frequently associated with periodic limb movements. Evidence from imaging and electrophysiological studies suggests that RLS is linked to changes in sensorimotor integration. Nevertheless, the underlying mechanisms have not been characterized, and the cortical origin has yet to be confirmed. The objective of the present study was to establish whether or not sensorimotor integration in RLS patients is impaired in the evening...
February 2017: Sleep Medicine
keyword
keyword
80123
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"