keyword
MENU ▼
Read by QxMD icon Read
search

dir

keyword
https://www.readbyqxmd.com/read/28933955/the-role-of-sex-related-alcohol-expectancies-in-alcohol-involved-consensual-and-nonconsensual-sex-among-women-of-asian-pacific-islander-and-women-of-european-race-ethnicity
#1
Allyson L Dir, Arthur R Andrews, Sarah M Wilson, Tatiana M Davidson, Amanda K Gilmore
Alcohol-involved sexual experiences, including incapacitated sexual assault and alcohol-involved sex, are major public health concerns among college women. Further, racial/ethnic diversity among college students is increasing, particularly with regard to increases in college students of Asian/Pacific Islander (API) race/ethnicity. Of relevance, evidence suggests differences in sexual assault rates across ethnicities and cultures; however, no known study to date has examined differences by ethnicity and first language in expectancies and experiences specifically surrounding alcohol and sex...
September 21, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28920426/methotrexate-camptothecin-prodrug-nanoassemblies-as-a-versatile-nanoplatform-for-biomodal-imaging-guided-self-active-targeted-and-synergistic-chemotherapy
#2
Yang Li, Jinyan Lin, Jinyuan Ma, Liang Song, Huirong Lin, Bowen Tang, Dengyue Chen, Guanghao Su, Shefang Ye, Xuan Zhu, Fang-Hong Luo, Zhenqing Hou
"All-in-one" carrier-free-based nano-multi-drug self-delivery system could combine triple advantages of small molecules, nanoscale characteristics, and synergistic combination therapy together. Researches have showed that dual-acting small molecular methotrexate (MTX) could target and kill the folate receptors-overexpressing cancer cells. Inspired by this mechanism, a novel collaborative "early-phase tumor-selective targeting and late-phase synergistic anticancer" approach was developed for the self-assembly of chemotherapeutic drug-drug conjugate, which showed various advantages of more simplicity, efficiency, and flexibility over the conventional approach that was only based on single or combination cancer chemotherapy...
September 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28913879/short-t2-imaging-using-a-3d-double-adiabatic-inversion-recovery-prepared-ultrashort-echo-time-cones-3d-dir-ute-cones-sequence
#3
Ya-Jun Ma, Yanchun Zhu, Xing Lu, Michael Carl, Eric Y Chang, Jiang Du
PURPOSE: To investigate high contrast imaging of short T2 tissues with a three-dimensional double adiabatic inversion recovery prepared ultrashort echo time Cones (3D DIR-UTE-Cones) sequence. METHODS: The sequence used two sequential adiabatic inversion pulses to suppress signals from long T2 tissues, followed by multispoke UTE acquisition to detect signals from short T2 tissues. The two adiabatic inversion pulses are identical with a center frequency located at the water peak, but the spectral width is broad enough to cover both water and fat frequencies...
September 14, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28905416/sar-and-scan-time-optimized-3d-whole-brain-double-inversion-recovery-imaging-at-7t
#4
Eberhard D Pracht, Thorsten Feiweier, Philipp Ehses, Daniel Brenner, Alard Roebroeck, Bernd Weber, Tony Stöcker
PURPOSE: The aim of this project was to implement an ultra-high field (UHF) optimized double inversion recovery (DIR) sequence for gray matter (GM) imaging, enabling whole brain coverage in short acquisition times ( ≈5 min, image resolution 1 mm(3) ). METHODS: A 3D variable flip angle DIR turbo spin echo (TSE) sequence was optimized for UHF application. We implemented an improved, fast, and specific absorption rate (SAR) efficient TSE imaging module, utilizing improved reordering...
September 14, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28901265/stereocomplexation-assisted-assembly-of-poly-g-glutamic-acid-graft-polylactide-nano-micelles-and-their-efficacy-as-anticancer-drug-carrier
#5
Shulin Dai, Yucheng Feng, Shuyi Li, Yuxiao Chen, Meiqing Liu, Chao Zhang, Wei Zhang, Yihua Yin
Micelles as drug carriers are characterized by their inherent instability due to the weak physical interactions that facilitate the self-assembly of amphiphilic block copolymers. As one of the strong physical interactions, the stereocomplexation between equal molar of enantiomeric polylactides, i.e., the poly(L-lactide) (PLLA) and poly(D-lactide) (PDLA), may be harnessed to obtain micelles with enhanced stability and drug loading capacity and consequent sustained release. In this paper, stereocomplexed micelles (γ-PGA-g-PLA micelles) were fabricated from the stereocomplexation between poly(γ-glutamic acid)-graft-PLLA (γ-PGA-g-PLLA) and poly(γ-glutamic acid)-graft-PDLA (γ-PGA-g-PDLA)...
September 11, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28892400/poly-vinyl-methyl-ether-maleic-anhydride-doped-peg-pla-nanoparticles-for-oral-paclitaxel-delivery-to-improve-bioadhesive-efficiency
#6
Qian Wang, Chan Li, Tianyang Ren, Shizhu Chen, Xiaoxia Ye, Hongbo Guo, Haibing He, Yu Zhang, Tian Yin, Xing-Jie Liang, Xing Tang
Bioadhesive nanoparticles based on poly(vinyl methyl ether/maleic anhydride) (PVMMA) and poly(ethylene glycol) methyl ether-b-poly(d,l-lactic acid) (mPEG-b-PLA) were produced by the emulsification solvent evaporation method. Paclitaxel was utilized as the model drug, with an encapsulation efficiency of up to 90.2 ± 4.0%. The nanoparticles were uniform and spherical in shape and exhibited a sustained drug release compared with Taxol. m-NPs also exhibited favorable bioadhesive efficiency at the same time. Coumarin 6 or DiR-loaded nanoparticles with/without PVMMA (C6-m-NPs/DiR-m-NPs or C6-p-NPs/DiR-p-NPs) were used for cellular uptake and intestinal adhesion experiments, respectively...
September 20, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28886577/what-s-the-harm-alcohol-and-marijuana-use-and-perceived-risks-of-unprotected-sex-among-adolescents-and-young-adults
#7
Allyson L Dir, Amanda K Gilmore, Angela D Moreland, Tatiana M Davidson, April L Borkman, Alyssa A Rheingold, Carla Kmett Danielson
The link between substance use and risky sexual behavior, particularly unprotected sex, among adolescents and young adults has been well established in the literature; however, less is known regarding how different patterns and types of substance use differentially relate to unprotected sex and perceived risks of unprotected sex. The current study examined perceived risks and unprotected sex among adolescents and young adults, and examined whether marijuana use, alcohol use, and dual marijuana and alcohol use were differentially linked to unprotected sex and perceived risks of unprotected sex...
September 1, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28874012/potential-resting-and-breeding-sites-of-sand-flies-diptera-psychodidae-and-their-habitat-characteristics-in-leishmaniasis-foci-of-dir-districts-khyber-pakhtunkhwa-pakistan
#8
Khurshaid Khan, Sobia Wahid, Nazma Habib Khan, Naheed Ali
Despite their medical importance, natural breeding sites of sand flies have been poorly explored. Detecting such sites is imperative in vector control strategies. This study aimed to identify potential breeding and resting microhabitats of sand flies and household risk factors associated with cutaneous leishmaniasis transmission in Dir districts, Khyber Pakhtunkhwa, Pakistan. Survey of indoor and outdoor habitats in four tehsils (subdistricts) of upper and lower Dir districts was carried out using sticky traps, flit method, and aspirator...
September 1, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28864401/implementing-radiation-dose-volume-liver-response-in-biomechanical-deformable-image-registration
#9
Daniel F Polan, Mary Feng, Theodore S Lawrence, Randall K Ten Haken, Kristy K Brock
PURPOSE: Understanding anatomic and functional changes in the liver resulting from radiation therapy is fundamental to the improvement of normal tissue complication probability models needed to advance personalized medicine. The ability to link pretreatment and posttreatment imaging is often compromised by significant dose-dependent volumetric changes within the liver that are currently not accounted for in deformable image registration (DIR) techniques. This study investigated using delivered dose, in combination with other patient factors, to biomechanically model longitudinal changes in liver anatomy for follow-up care and re-treatment planning...
June 27, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28834771/fe-ii-cu-ii-interaction-on-goethite-stimulated-by-an-iron-reducing-bacteria-aeromonas-hydrophila-hs01-under-anaerobic-conditions
#10
Liang Tao, Zhen-Ke Zhu, Fang-Bai Li, Shan-Li Wang
Copper is a trace element essential for living creatures, but copper content in soil should be controlled, as it is toxic. The physical-chemical-biological features of Cu in soil have a significant correlation with the Fe(II)/Cu(II) interaction in soil. Of significant interest to the current study is the effect of Fe(II)/Cu(II) interaction conducted on goethite under anaerobic conditions stimulated by HS01 (a dissimilatory iron reduction (DIR) microbial). The following four treatments were designed: HS01 with α-FeOOH and Cu(II) (T1), HS01 with α-FeOOH (T2), HS01 with Cu(II) (T3), and α-FeOOH with Cu(II) (T4)...
August 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28834555/a-method-to-detect-landmark-pairs-accurately-between-intra-patient-volumetric-medical-images
#11
Deshan Yang, Miao Zhang, Xiao Chang, Yabo Fu, Shi Liu, Harold H Li, Sasa Mutic, Ye Duan
PURPOSES: An image processing procedure was developed in this study to detect large quantity of landmark pairs accurately in pairs of volumetric medical images. The detected landmark pairs can be used to evaluate of deformable image registration (DIR) methods quantitatively. METHODS: Landmark detection and pair matching were implemented in a Gaussian pyramid multi-resolution scheme. A 3D scale-invariant feature transform (SIFT) feature detection method and a 3D Harris-Laplacian corner detection method were employed to detect feature points, i...
August 23, 2017: Medical Physics
https://www.readbyqxmd.com/read/28830203/multimodal-image-registration-for-the-identification-of-dominant-intraprostatic-lesion-in-high-precision-radiotherapy-treatments
#12
Delia Ciardo, Barbara Alicja Jereczek-Fossa, Giuseppe Petralia, Giorgia Timon, Dario Zerini, Raffaella Cambria, Elena Rondi, Federica Cattani, Alessia Bazani, Rosalinda Ricotti, Maria Garioni, Davide Maestri, Giulia Marvaso, Paola Romanelli, Marco Riboldi, Guido Baroni, Roberto Orecchia
PURPOSE: The integration of computed tomography (CT) and multiparametric magnetic resonance imaging (mpMRI) is a challenging task in high-precision radiotherapy for prostate cancer. A simple methodology for multimodal deformable image registration (DIR) of prostate cancer patients is presented. METHODS: CT and mpMRI of ten patients were considered. Organs at risk and prostate were contoured on both scans. The dominant intraprostatic lesion was additionally delineated on magnetic resonance imaging...
August 22, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28828623/efficacy-of-double-inversion-recovery-magnetic-resonance-imaging-for-the-evaluation-of-the-synovium-in-the-femoro-patellar-joint-without-contrast-enhancement
#13
Ye Na Son, Wook Jin, Geon-Ho Jahng, Jang Gyu Cha, Yong Sung Park, Seong Jong Yun, So Young Park, Ji Seon Park, Kyung Nam Ryu
OBJECTIVE: To investigate the efficacy of double inversion recovery (DIR) sequence for evaluating the synovium of the femoro-patellar joint without contrast enhancement (CE). METHODS: Two radiologists independently evaluated the axial DIR and CE T1-weighted fat-saturated (CET1FS) images of 33 knees for agreement; the visualisation and distribution of the synovium were evaluated using a four-point visual scaling system at each of the five levels of the femoro-patellar joint and the location of the thickest synovium...
August 21, 2017: European Radiology
https://www.readbyqxmd.com/read/28807219/effects-of-p38-mitogen-activated-protein-kinase-on-lung-ischemia-reperfusion-injury-in-diabetic-rats
#14
Linlin Song, Di Li, Juan Wang, Chao Meng, Xiaoguang Cui
BACKGROUND: Lung ischemia-reperfusion injury (LIRI) is a pathologic process that is observed in several clinical conditions, and p38 mitogen-activated protein kinase (MAPK) is involved. Diabetes mellitus (DM) results in an increased incidence of ischemia-induced organ damage. The aims of this study were to examine the effects of DM on LIRI in a rat model of DM and to explore the possible mechanisms in relation to the p38 MAPK pathway. METHODS: Forty rats were randomly divided into the following five groups (n = 8 each): a control + sham group, a control + IR group (CIR), a DM + sham group, a DM + IR group (DIR), and a DM + IR + SB203580 group...
August 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28802976/prognostic-factors-associated-with-the-accuracy-of-deformable-image-registration-in-lung-cancer-patients-treated-with-stereotactic-body-radiotherapy
#15
Yasuharu Sugawara, Hidenobu Tachibana, Noriyuki Kadoya, Nozomi Kitamura, Amit Sawant, Keiichi Jingu
We evaluated the accuracy of an in-house program in lung stereotactic body radiation therapy (SBRT) cancer patients, and explored the prognostic factors associated with the accuracy of deformable image registrations (DIRs). The accuracy of the 3 programs which implement the free-form deformation and the B-spline algorithm was compared regarding the structures on 4-dimensional computed tomography (4DCT) image datasets between the peak-inhale and peak-exhale phases. The dice similarity coefficient (DSC) and normalized DSC (NDSC) were measured for the gross tumor volumes from 19 lung SBRT patients...
August 9, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28800299/representing-the-dosimetric-impact-of-deformable-image-registration-errors
#16
Jason Vickress, Jerry Battista, Rob Barnett, Slav Yartsev
Deformable image registration (DIR) is emerging as a tool in radiation therapy for calculating the cumulative dose distribution across multiple fractions of treatment. Unfortunately, due to the variable nature of DIR algorithms and dependence of performance on image quality, registration errors can result in dose accumulation errors. In this study, landmarked images were used to characterize the DIR error throughout an image space and determine its impact on dosimetric analysis. Ten thoracic 4DCT images with 300 landmarks per image study matching the end-inspiration and end-expiration phases were obtained from 'dir-labs'...
August 11, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28771684/high-y-chromosomal-differentiation-among-ethnic-groups-of-dir-and-swat-districts-pakistan
#17
Inam Ullah, Jill K Olofsson, Ashot Margaryan, Melissa Ilardo, Habib Ahmad, Martin Sikora, Anders J Hansen, Muhammad Shahid Nadeem, Numan Fazal, Murad Ali, Anders Buchard, Brian E Hemphill, Eske Willerslev, Morten E Allentoft
The ethnic groups that inhabit the mountainous Dir and Swat districts of northern Pakistan are marked by high levels of cultural and phenotypic diversity. To obtain knowledge of the extent of genetic diversity in this region, we investigated Y-chromosomal diversity in five population samples representing the three main ethnic groups residing within these districts, including Gujars, Pashtuns and Kohistanis. A total of 27 Y-chromosomal short tandem repeats (Y-STRs) and 331 Y-chromosomal single nucleotide polymorphisms (Y-SNPs) were investigated...
August 3, 2017: Annals of Human Genetics
https://www.readbyqxmd.com/read/28756606/a-novel-imaging-technique-for-better-detecting-new-lesions-in-multiple-sclerosis
#18
Paul Eichinger, Hanni Wiestler, Haike Zhang, Viola Biberacher, Jan S Kirschke, Claus Zimmer, Mark Mühlau, Benedikt Wiestler
We developed a tool that performs longitudinal subtraction of 3D double inversion recovery (DIR) images in follow-up magnetic resonance (MR) examinations of patients with multiple sclerosis. As DIR sequences show a high lesion-to-parenchyma contrast, we hypothesized that such a tool might lead to increased sensitivity for new lesions as well as to speeding up the routine clinical work-up of follow-up MR imaging in multiple sclerosis by directly visualizing new lesions. DIR subtraction images of serial MR examinations were calculated in 106 patients with multiple sclerosis...
July 29, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28756043/impact-of-angiosome-and-non-angiosome-targeted-peroneal-bypass-on-limb-salvage-and-healing-in-patients-with-chronic-limb-threatening-ischemia
#19
Jean-Baptiste Ricco, Mauro Gargiulo, Andrea Stella, Mohammad Abualhin, Enrico Gallitto, Mathieu Desvergnes, Romain Belmonte, Fabrice Schneider
BACKGROUND: Direct (DIR) or indirect (IND) revascularization of pedal angiosomes in patients with chronic limb-threatening ischemia (CLTI) has an unclear impact on limb salvage and healing. The aim of this study was to evaluate the outcomes of DIR and IND revascularization in patients with a peroneal bypass and tissue loss. METHODS: We conducted a retrospective study of a prospectively maintained database in two European university centers from 2004 to 2015. We extracted from this database all patients with CLTI and tissue loss who had received a bypass to the peroneal artery...
July 26, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28755425/accuracy-of-eight-deformable-image-registration-dir-methods-for-tomotherapy-megavoltage-computed-tomography-mvct-images
#20
Wannapha Nobnop, Hudsaleark Neamin, Imjai Chitapanarux, Somsak Wanwilairat, Vicharn Lorvidhaya, Taweap Sanghangthum
INTRODUCTION: The application of deformable image registration (DIR) to megavoltage computed tomography (MVCT) images benefits adaptive radiotherapy. This study aims to quantify the accuracy of DIR for MVCT images when using different deformation methods assessed in a cubic phantom and nasopharyngeal carcinoma (NPC) patients. METHODS: In the control studies, the DIR accuracy in air-tissue and tissue-tissue interface areas was observed using twelve shapes of acrylic and tissue-equivalent material inserted in the phantom...
July 29, 2017: Journal of Medical Radiation Sciences
keyword
keyword
80121
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"