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developmental coordination disorders

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https://www.readbyqxmd.com/read/28098503/relationship-between-perceived-competence-and-performance-during-real-and-virtual-motor-tasks-by-children-with-developmental-coordination-disorder
#1
Batya Engel-Yeger, Rotem Sido, Aviva Mimouni-Bloch, Patrice L Weiss
PURPOSE: (i) To compare children with DCD and typically developing participants via standard motor assessments, two interactive virtual games, measures of physical, social and cognitive self-competence and feedback while playing the virtual games and (ii) To examine the contribution of age and each motor assessment to predict self-competence. METHODS: Participants were 25 boys with DCD and 25 typically developing boys, aged 5-9 years. They completed the M-ABC-2, the Pictorial Scale of Perceived Competence, the 6-Minute Walk Test, and then played the two Kinect games and completed the Short Feedback Questionnaire for Children...
January 18, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28069923/map7-regulates-axon-collateral-branch-development-in-dorsal-root-ganglia-neurons
#2
Stephen R Tymanskyj, Benjamin Yang, Aditi Falnikar, Angelo C Lepore, Le Ma
: Collateral branches from axons are key components of functional neural circuits that allow neurons to connect with multiple synaptic targets. Like axon growth and guidance, formation of collateral branches depends on the regulation of microtubules, but how such regulation is coordinated to ensure proper circuit development is not known. Based on microarray analysis, we have identified a role for microtubule-associated protein 7 (MAP7) during collateral branch development of dorsal root ganglia (DRG) sensory neurons...
January 9, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28027529/automatic-classification-of-gait-in-children-with-early-onset-ataxia-or-developmental-coordination-disorder-and-controls-using-inertial-sensors
#3
Andrea Mannini, Octavio Martinez-Manzanera, Tjitske F Lawerman, Diana Trojaniello, Ugo Della Croce, Deborah A Sival, Natasha M Maurits, Angelo Maria Sabatini
Early-Onset Ataxia (EOA) and Developmental Coordination Disorder (DCD) are two conditions that affect coordination in children. Phenotypic identification of impaired coordination plays an important role in their diagnosis. Gait is one of the tests included in rating scales that can be used to assess motor coordination. A practical problem is that the resemblance between EOA and DCD symptoms can hamper their diagnosis. In this study we employed inertial sensors and a supervised classifier to obtain an automatic classification of the condition of participants...
December 2, 2016: Gait & Posture
https://www.readbyqxmd.com/read/28018285/neural-signature-of-dcd-a-critical-review-of-mri-neuroimaging-studies
#4
REVIEW
Maëlle Biotteau, Yves Chaix, Mélody Blais, Jessica Tallet, Patrice Péran, Jean-Michel Albaret
The most common neurodevelopmental disorders (e.g., developmental dyslexia (DD), autism, attention-deficit hyperactivity disorder (ADHD)) have been the subject of numerous neuroimaging studies, leading to certain brain regions being identified as neural correlates of these conditions, referring to a neural signature of disorders. Developmental coordination disorder (DCD), however, remains one of the least understood and studied neurodevelopmental disorders. Given the acknowledged link between motor difficulties and brain features, it is surprising that so few research studies have systematically explored the brains of children with DCD...
2016: Frontiers in Neurology
https://www.readbyqxmd.com/read/28012789/reliability-and-validity-of-the-finnish-version-of-the-motor-observation-questionnaire-for-teachers
#5
P Asunta, H Viholainen, T Ahonen, M Cantell, J Westerholm, M M Schoemaker, P Rintala
OBJECTIVES: Observational screening instruments are often used as an effective, economical first step in the identification of children with Developmental Coordination Disorder (DCD). The aim was to investigate the psychometric properties of the Finnish version of the Motor Observation Questionnaire for Teachers (MOQ-T-FI). METHODS: The psychometric properties were tested using two separate samples (S1: age range 6-12, M 9y 5mo, females 101, males 92; S2: age range 6-9, M 7y 7mo, females 404, males 446)...
December 21, 2016: Human Movement Science
https://www.readbyqxmd.com/read/28009726/the-emergence-of-autism-spectrum-disorder-insights-gained-from-studies-of-brain-and-behaviour-in-high-risk-infants
#6
Kandice J Varcin, Shafali S Jeste
PURPOSE OF REVIEW: We review studies of infants at risk for autism spectrum disorder (ASD), proposing that the earliest manifestations of disrupted brain development can shed light on prebehavioural markers of risk and mechanisms underlying the heterogeneity of ASD. RECENT FINDINGS: Prospective, longitudinal studies of infants at risk for ASD have revealed that behavioural signs of ASD are generally not observed until the second year of life. The developmental signs within the first year are often subtle and rooted in processes outside the core diagnostic domains of ASD, such as motor and visual perceptual function...
December 21, 2016: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/27999532/genetic-feedback-regulation-of-frontal-cortical-neuronal-ensembles-through-activity-dependent-arc-expression-and-dopaminergic-input
#7
Surjeet Mastwal, Vania Cao, Kuan Hong Wang
Mental functions involve coordinated activities of specific neuronal ensembles that are embedded in complex brain circuits. Aberrant neuronal ensemble dynamics is thought to form the neurobiological basis of mental disorders. A major challenge in mental health research is to identify these cellular ensembles and determine what molecular mechanisms constrain their emergence and consolidation during development and learning. Here, we provide a perspective based on recent studies that use activity-dependent gene Arc/Arg3...
2016: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/27996316/developmental-coordination-disorder-plus-oculomotor-and-visuospatial-impairment-as-neurodevelopmental-heralds-of-psychosis-proneness
#8
Michele Poletti, Eva Gebhardt, Andrea Raballo
Aiming at preventing transitions to more severe psychopathology and boosted by the availability of operational criteria to identify help-seeking subjects at increased risk for psychosis, research into the early prodromal phases of psychosis is attracting a growing clinical interest. Furthermore, the focus of early detection is gradually shifting from prodromal syndromes to the premorbid period. Although mainly driven by clinical-pragatic aims, such a shift is coherent with the neurodevelopmental hypothesis of schizophrenia that might offer a unifying, developmentally informed conceptual framework for early detection...
December 20, 2016: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/27984818/the-effect-of-an-integrated-perceived-competence-and-motor-intervention-in-children-with-developmental-coordination-disorder
#9
Johannes J Noordstar, Janjaap van der Net, Lia Voerman, Paul J M Helders, Marian J Jongmans
BACKGROUND AND AIMS: Children with DCD have lower self-perceptions and are less physically active than typically developing children. The aim of this quasi-experimental study was to investigate whether an integrated perceived competence and motor intervention affects DCD children's motor performance, self-perceptions, and physical activity compared with a motor intervention only. METHODS AND PROCEDURES: The intervention group consisted of 20 children and the care-as-usual group consisted of 11 children, all aged 7-10 years...
January 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27984183/repeated-prenatal-exposure-to-valproic-acid-results-in-cerebellar-hypoplasia-and-ataxia
#10
Stacey L Main, Randy J Kulesza
Autism spectrum disorder (ASD) is a developmental brain disorder characterized by restricted and repetitive patterns of behavior, social and communication defects, and is commonly associated with difficulties with motor coordination. The etiology of ASD, while mostly idiopathic, has been linked to hereditary factors and teratogens, such as valproic acid (VPA). VPA is used clinically to treat epilepsy, mood disorders, and in the prevention of migraines. The use of VPA during pregnancy significantly increases the risk of ASD in the offspring...
October 27, 2016: Neuroscience
https://www.readbyqxmd.com/read/27981910/multilevel-analysis-of-locomotion-in-immature-preparations-suggests-innovative-strategies-to-reactivate-stepping-after-spinal-cord-injury
#11
Michele R Brumley, Pierre A Guertin, Giuliano Taccola
Locomotion is one of the most complex motor behaviors. Locomotor patterns change during early life, reflecting development of numerous peripheral and hierarchically organized central structures. Among them, the spinal cord is of particular interest since it houses the central pattern generator (CPG) for locomotion. This main command center is capable of eliciting and coordinating complex series of rhythmic neural signals sent to motoneurons and to corresponding target-muscles for basic locomotor activity. For a long-time, the CPG has been considered a black box...
December 14, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27977875/developmental-changes-in-neuromagnetic-rhythms-and-network-synchrony-in-autism
#12
Vasily A Vakorin, Sam M Doesburg, Rachel C Leung, Vanessa M Vogan, Evdokia Anagnostou, Margot J Taylor
OBJECTIVE: There is gathering consensus that altered connectivity is a hallmark of the autistic brain. This includes atypical neural oscillations and their coordination across brain regions, which are understood to mediate information processing and integration. It remains unclear if and how connectivity in various neurophysiological frequency ranges develops atypically in autism spectrum disorder. METHODS: To address this in a cross-sectional sample, we recorded resting-state magnetoencephalography (MEG) from 134 children and adolescents with and without ASD, and calculated resting spectral power and inter-regional synchrony (functional connectivity)...
December 15, 2016: Annals of Neurology
https://www.readbyqxmd.com/read/27939726/the-use-of-visually-guided-behaviour-in-children-with-developmental-coordination-disorder-dcd-when-crossing-a-virtual-road
#13
Catherine Purcell, Kate Wilmut, John P Wann
The ability to safely cross a road is a perceptual-motor skill that involves coordination between a pedestrian's perception of the approaching vehicles and their locomotive capability to execute the road crossing action. Developmental Coordination Disorder (DCD) is a chronic disorder that is characterised by significant motor difficulties that impact on daily living, including a reduced ability to perform visually guided actions. A total of 25 typically developing primary school aged children and 25 age- and gender-matched children with DCD were presented with a virtual desktop task that required them to select suitable temporal crossing gaps between vehicles a stream of traffic approaching at either 20mph, 30mph or 40mph from the near-side (one-lane) or both near+far-sides (two-lane)...
December 7, 2016: Human Movement Science
https://www.readbyqxmd.com/read/27922856/health-profiles-and-associated-service-use-among-adults-with-hiv-and-intellectual-and-developmental-disabilities
#14
Yona Lunsky, Anna Durbin, Hilary K Brown, Symron Bansal, Marina Heifetz, Tony Antoniou
OBJECTIVE (S): Due to the commonly held notion that individuals with intellectual and developmental disabilities (IDD) have low risk of HIV acquisition, we compared the prevalence of HIV infection among people with and without IDD. We also examined health status and health service use among the HIV-infected group. DESIGN: Population-based cohort study using linked administrative health and social services databases. METHODS: We compared HIV prevalence between Ontario adults with IDD (n=64,008) and a 20% random sample of Ontario adults without IDD...
December 5, 2016: AIDS
https://www.readbyqxmd.com/read/27912103/gait-symmetry-in-individuals-with-and-without-developmental-coordination-disorder
#15
K Wilmut, J Gentle, A L Barnett
BACKGROUND: Symmetry between the left and right side of the body during locomotion is key in a coordinated gait cycle and is also thought to be important in terms of efficiency. Although previous studies have identified aspects of the gait cycle which are atypical in children and adults with Developmental Coordination Disorder (DCD), studies have not considered whether this could be explained by asymmetrical gait. METHOD AND PROCEDURE: The current study included 62 participants with and 62 without DCD (aged 7-34 years)...
January 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27911282/role-of-rehabilitation-in-hurler-s-syndrome
#16
Sudhir Ramkishore Mishra, Mona Shastri, Jaishree Ramesh
Hurler syndrome is an inherited autosomal recessive disorder of lysosomal accumulation of un-degraded glucosaminoglycan secondary to deficiency of a-L-Iduronidase enzyme. It is most severe form of Mucopolysaccharidosis with incidence of 1:100 000. It has multisystemic involvement leading to multiple deformity, disability and death within 10th years of life. A 2 year old boy presented with umbilical hernia, gross developmental delay and a progressive spinal deformity. On detailed clinical, radiological and laboratory investigation he was diagnosed as Hurler's syndrome...
November 25, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27902527/white-matter-alterations-in-adults-with-probable-developmental-coordination-disorder-an-mri-diffusion-tensor-imaging-study
#17
Jacqueline Williams, Saman R Kashuk, Peter H Wilson, Graham Thorpe, Gary F Egan
Movement skill difficulties in children [or developmental coordination disorder (DCD)] often persist into adulthood (in up to 70% of cases). The suggestion of white matter microstructure alterations in children with DCD raises the question of whether similar alterations are present in adults with probable DCD (pDCD). Twelve adults with pDCD and 11 adults without pDCD underwent diffusion tensor imaging. The results showed that the pDCD group had significantly lower fractional anisotropy in the corticospinal tract and superior longitudinal fasciculus and lower mean diffusivity in the internal capsule and inferior longitudinal fasciculus...
January 18, 2017: Neuroreport
https://www.readbyqxmd.com/read/27899082/interventions-to-improve-gross-motor-performance-in-children-with-neurodevelopmental-disorders-a-meta-analysis
#18
Barbara R Lucas, Elizabeth J Elliott, Sarah Coggan, Rafael Z Pinto, Tracy Jirikowic, Sarah Westcott McCoy, Jane Latimer
BACKGROUND: Gross motor skills are fundamental to childhood development. The effectiveness of current physical therapy options for children with mild to moderate gross motor disorders is unknown. The aim of this study was to systematically review the literature to investigate the effectiveness of conservative interventions to improve gross motor performance in children with a range of neurodevelopmental disorders. METHODS: A systematic review with meta-analysis was conducted...
November 29, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27888271/investigation-of-the-association-between-motor-stereotypy-behavior-with-fundamental-movement-skills-adaptive-functioning-and-autistic-spectrum-disorder-symptomology-in-children-with-intellectual-disabilities
#19
Joanne L Powell, Lydia Pringle, Matt Greig
Motor stereotypy behaviors are patterned, coordinated, repetitive behaviors that are particularly evident in those with an autistic spectrum disorder and intellectual disabilities. The extent to which motor stereotypy behavior severity is associated with motor skills and maladaptive behavior, measures of adaptive functioning, along with fundamental movement skills and degree of autistic spectrum disorder symptomology is assessed in this preliminary report. Twelve participants, aged 7 to 16 years, with a reported motor stereotypy behavior and either mild or severe intellectual disability comprising developmental or global delay took part in the study...
November 25, 2016: Journal of Child Neurology
https://www.readbyqxmd.com/read/27876401/developmental-coordination-disorder-and-its-cause-the-road-less-travelled
#20
Michael G Wade, Makinzee Kazeck
We critically review the research literature that seeks to focus on the possible cause of children diagnosed with developmental coordination disorder (DCD). In so doing we contrast the traditional information processing (IP) approach as a model to explain the causal factors that account for the motor deficits present in children with DCD, with a dynamical systems (DS) account which argues that coordination deficits in children with DCD is less to do with problems of poor internal models (a cornerstone of IP theory) and more with a degrading of perception-action coupling...
November 19, 2016: Human Movement Science
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