keyword
https://read.qxmd.com/read/32434996/monounsaturated-fat-rapidly-induces-hepatic-gluconeogenesis-and-whole-body-insulin-resistance
#1
RANDOMIZED CONTROLLED TRIAL
Theresia Sarabhai, Sabine Kahl, Julia Szendroedi, Daniel F Markgraf, Oana-Patricia Zaharia, Cristina Barosa, Christian Herder, Frithjof Wickrath, Pavel Bobrov, Jong-Hee Hwang, John Griffith Jones, Michael Roden
BACKGROUNDWhile saturated fat intake leads to insulin resistance and nonalcoholic fatty liver, Mediterranean-like diets enriched in monounsaturated fatty acids (MUFA) may have beneficial effects. This study examined effects of MUFA on tissue-specific insulin sensitivity and energy metabolism.METHODSA randomized placebo-controlled cross-over study enrolled 16 glucose-tolerant volunteers to receive either oil (OIL, ~1.18 g/kg), rich in MUFA, or vehicle (VCL, water) on 2 occasions. Insulin sensitivity was assessed during preclamp and hyperinsulinemic-euglycemic clamp conditions...
May 21, 2020: JCI Insight
https://read.qxmd.com/read/28746591/the-therapeutic-challenge-of-giant-splenic-artery-aneurysm-a-case-repport
#2
Paulo Kauffman, Antonio Luiz de Vasconcellos Macedo, Roberto Sacilotto, Adriano Tachibana, Sergio Kuzniec, Lucas Lembrança Pinheiro, Nelson Wolosker
Giant splenic artery aneurysm is a rare condition that represents an eminent life threatening for the patient, requiring, therefore, urgent surgical correction. A 61-year-old woman, former smoker, hypertensive, hypercholesterolemic and multipara sought our service because of a large tumor in the mesogastrium, which was an abdominal ultrasound finding. Despite the size of the tumor, the patient was asymptomatic. The angiotomography and the magnetic resonance image of the abdomen were suggestive of giant splenic artery aneurysm with more than 10cm in diameter that was confirmed by an angiography...
July 2017: Einstein
https://read.qxmd.com/read/28614428/intrapancreatic-accessory-spleen
#3
Marcelo Protásio Dos Santos, Aline Pacheco de Rezende, Paulo Vicente Dos Santos, José Eduardo Gonçalves, Fernando Bray Beraldo, Adriano Pereira Sampaio
An asymptomatic 79-year-old woman, with incidental finding on abdominal ultrasound of a solid nodule in the tail of the pancreas. Magnetic resonance imaging showed a 12mm solid tumor. The suggested diagnosis was pancreatic neuroendocrine tumor. The pathological examination showed an intrapancreatic splenic tissue. This is a rare ectopic location of spleen tissue and it should be considered in the differential diagnosis of pancreatic solid tumors.
July 2017: Einstein
https://read.qxmd.com/read/28591322/myocardial-viability-on-cardiac-magnetic-resonance
#4
REVIEW
Ana Luiza Mansur Souto, Rafael Mansur Souto, Isabella Cristina Resende Teixeira, Marcelo Souto Nacif
The study of myocardial viability is of great importance in the orientation and management of patients requiring myocardial revascularization or angioplasty. The technique of delayed enhancement (DE) is accurate and has transformed the study of viability into an easy test, not only for the detection of fibrosis but also as a binary test detecting what is viable or not. On DE, fibrosis equal to or greater than 50% of the segmental area is considered as non-viable, whereas that below 50% is considered viable...
May 2017: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/28562831/three-dimensional-volumetric-assessment-of-diastolic-function-by-cardiac-magnetic-resonance-imaging-the-multi-ethnic-study-of-atherosclerosis-mesa
#5
COMPARATIVE STUDY
Marcelo S Nacif, Andre L C Almeida, Alistair A Young, Brett R Cowan, Anderson C Armstrong, Eunice Yang, Christopher T Sibley, W Gregory Hundley, Songtao Liu, Joao Ac Lima, David A Bluemke
Background: Cardiac Magnetic Resonance is in need of a simple and robust method for diastolic function assessment that can be done with routine protocol sequences. Objective: To develop and validate a three-dimensional (3D) model-based volumetric assessment of diastolic function using cardiac magnetic resonance (CMR) imaging and compare the results obtained with the model with those obtained by echocardiography. Methods: The study participants provided written informed consent and were included if having undergone both echocardiography and cine steady-state free precession (SSFP) CMR on the same day...
2017: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/28444083/interictal-abnormal-fmri-activation-of-visual-areas-during-a-motor-task-cued-by-visual-stimuli-in-migraine
#6
JOURNAL ARTICLE
Adriana Bastos Conforto, Khallil Taverna Chaim, Mario Fernando Prieto Peres, André Leite Gonçalves, Inara Laurindo Siqueira, Maria Angela Maramaldo Barreiros, Edson Amaro
OBJECTIVE: To assess changes in blood-oxygen-level-dependent activity after light deprivation compared to regular light exposure in subjects with migraine in the interictal state and in controls. METHODS: Ten subjects with migraine and ten controls participated in two sessions of functional magnetic resonance imaging. In each session, they performed a finger-tapping task with the right hand, cued by visual stimuli. They were scanned before and after 30 minutes of light deprivation or light exposure...
January 2017: Einstein
https://read.qxmd.com/read/28112681/acute-dietary-fat-intake-initiates-alterations-in-energy-metabolism-and-insulin-resistance
#7
RANDOMIZED CONTROLLED TRIAL
Elisa Álvarez Hernández, Sabine Kahl, Anett Seelig, Paul Begovatz, Martin Irmler, Yuliya Kupriyanova, Bettina Nowotny, Peter Nowotny, Christian Herder, Cristina Barosa, Filipa Carvalho, Jan Rozman, Susanne Neschen, John G Jones, Johannes Beckers, Martin Hrabě de Angelis, Michael Roden
BACKGROUND: Dietary intake of saturated fat is a likely contributor to nonalcoholic fatty liver disease (NAFLD) and insulin resistance, but the mechanisms that initiate these abnormalities in humans remain unclear. We examined the effects of a single oral saturated fat load on insulin sensitivity, hepatic glucose metabolism, and lipid metabolism in humans. Similarly, initiating mechanisms were examined after an equivalent challenge in mice. METHODS: Fourteen lean, healthy individuals randomly received either palm oil (PO) or vehicle (VCL)...
February 1, 2017: Journal of Clinical Investigation
https://read.qxmd.com/read/28076605/isolated-primary-amyloidosis-of-the-inferior-rectus-muscle-mimicking-graves-orbitopathy
#8
Mário Luiz Ribeiro Monteiro, Allan Christian Pieroni Gonçalves, Alanna Mara Pinheiro Sobreira Bezerra
The diagnosis of Graves' orbitopathy is usually straightforward. However, orbital diseases that mimick some clinical signs of Graves' orbitopathy may cause diagnostic confusion, particularly when associated to some form of thyroid dysfunction. This report describes the rare occurrence of localized inferior rectus muscle amyloidosis in a patient with autoimmune hypothyroidism, who was misdiagnosed as Graves' orbitopathy. A 48-year-old man complained of painless progressive proptosis on the left side and intermittent vertical diplopia for 6 months...
2016: Einstein
https://read.qxmd.com/read/27982271/cardiac-magnetic-resonance-verified-myocardial-fibrosis-in-chagas-disease-clinical-correlates-and-risk-stratification
#9
JOURNAL ARTICLE
Marly Uellendahl, Maria Eduarda Menezes de Siqueira, Eveline Barros Calado, Roberto Kalil-Filho, Dário Sobral, Clébia Ribeiro, Wilson Oliveira, Silvia Martins, Jagat Narula, Carlos Eduardo Rochitte
BACKGROUND: Chagas disease (CD) is an important cause of heart failure and mortality, mainly in Latin America. This study evaluated the morphological and functional characteristics of the heart as well the extent of myocardial fibrosis (MF) in patients with CD by cardiac magnetic resonance (CMR). The prognostic value of MF evaluated by myocardial-delayed enhancement (MDE) was compared with that via Rassi score. METHODS: This study assessed 39 patients divided into 2 groups: 28 asymptomatic patients as indeterminate form group (IND); and symptomatic patients as Chagas Heart Disease (CHD) group...
November 2016: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/27812640/applications-for-a-hybrid-operating-room-in-thoracic-surgery-from-multidisciplinary-procedures-to-image-guided-video-assisted-thoracoscopic-surgery
#10
Ricardo Mingarini Terra, Juliano Ribeiro Andrade, Alessandro Wasum Mariani, Rodrigo Gobbo Garcia, Jose Ernesto Succi, Andrey Soares, Paulo Marcelo Zimmer
The concept of a hybrid operating room represents the union of a high-complexity surgical apparatus with state-of-the-art radiological tools (ultrasound, CT, fluoroscopy, or magnetic resonance imaging), in order to perform highly effective, minimally invasive procedures. Although the use of a hybrid operating room is well established in specialties such as neurosurgery and cardiovascular surgery, it has rarely been explored in thoracic surgery. Our objective was to discuss the possible applications of this technology in thoracic surgery, through the reporting of three cases...
September 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/27759826/multiparametric-magnetic-resonance-imaging-findings-of-prostatic-pure-leiomyomas
#11
JOURNAL ARTICLE
Thais Caldara Mussi, Yves Bohrer Costa, Marcos Takeo Obara, Marcos Roberto Gomes de Queiroz, Rodrigo Gobbo Garcia, José Antonio Domingos Cianciarulo Longo, Gustavo Caserta Lemos, Ronaldo Hueb Baroni
Objective: To describe the imaging findings of prostatic tumors nonadenocarcinoma on multiparametric magnetic resonance imaging. Methods: A total of 200 patients underwented multiparametric magnetic resonance imaging of the prostate for screening for prostate cancer, from August 2013 to September 2014, followed by biopsy with ultrasound/magnetic resonance imaging fusion. Results: We found three pathologic proved cases of prostatic pure leiomyomas (0...
July 2016: Einstein
https://read.qxmd.com/read/27759788/understanding-the-international-consensus-for-acute-pancreatitis-classification-of-atlanta-2012
#12
JOURNAL ARTICLE
Gleim Dias de Souza, Luciana Rodrigues Queiroz Souza, Ronaldo Máfia Cuenca, Bárbara Stephane de Medeiros Jerônimo, Guilherme Medeiros de Souza, Vinícius Martins Vilela
INTRODUCTION: Contrast computed tomography and magnetic resonance imaging are widely used due to its image quality and ability to study pancreatic and peripancreatic morphology. The understanding of the various subtypes of the disease and identification of possible complications requires a familiarity with the terminology, which allows effective communication between the different members of the multidisciplinary team. AIM: Demonstrate the terminology and parameters to identify the different classifications and findings of the disease based on the international consensus for acute pancreatitis ( Atlanta Classification 2012)...
2016: Brazilian Archives of Digestive Surgery: ABCD
https://read.qxmd.com/read/27305111/cardiac-magnetic-resonance-and-computed-tomography-in-hypertrophic-cardiomyopathy-an-update
#13
REVIEW
Diogo Costa Leandro de Oliveira, Fernanda Boldrini Assunção, Alair Agusto Sarmet Moreira Damas Dos Santos, Marcelo Souto Nacif
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease and represents the main cause of sudden death in young patients. Cardiac magnetic resonance (CMR) and cardiac computed tomography (CCT) are noninvasive imaging methods with high sensitivity and specificity, useful for the establishment of diagnosis and prognosis of HCM, and for the screening of patients with subclinical phenotypes. The improvement of image analysis by CMR and CCT offers the potential to promote interventions aiming at stopping the natural course of the disease...
August 2016: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/27305110/reproducibility-of-gadolinium-enhancement-patterns-and-wall-thickness-in-hypertrophic-cardiomyopathy
#14
JOURNAL ARTICLE
Gaston A Rodriguez-Granillo, Alejandro Deviggiano, Carlos Capunay, Macarena C De Zan, Patricia Carrascosa
BACKGROUND: Reproducibility data of the extent and patterns of late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM) is limited. OBJECTIVE: To explore the reproducibility of regional wall thickness (WT), LGE extent, and LGE patterns in patients with HCM assessed with cardiac magnetic resonance (CMR). METHODS: The extent of LGE was assessed by the number of segments with LGE, and by the total LV mass with LGE (% LGE); and the pattern of LGE-CMR was defined for each segment...
July 2016: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/27275591/impact-of-neoadjuvant-therapy-in-downstaging-of-lower-rectal-adenocarcinoma-and-the-role-of-pelvic-magnetic-resonance-in-staging
#15
JOURNAL ARTICLE
Karina Dagre Magri, Fang Chia Bin, Fernanda Bellotti Formiga, Thiago da Silveira Manzione, Caroline Merci Caliari de Neves Gomes, Paulo de Azeredo Passos Candelári, Jorge Alberto Ortiz, Wilmar Artur Klug, José Mandia, Peretz Capelhuchnik
OBJECTIVE: to evaluate the effect of neoadjuvant therapy on the stage (TNM) of patients with rectal adenocarcinoma and validate the use of MRI as a method of determining locoregional stage. METHODS: we conducted a retrospective study of 157 patients with lower rectum adenocarcinoma, whom we divided into two groups: Group 1, 81 patients (52%) who had undergone surgical treatment initially, with the purpose to analyze the accuracy of locoregional staging by pelvic magnetic resonance imaging throug the comparison of radiological findings with pathological ones; Group 2, 76 patients (48%), who had been submitted to neoadjuvant therapy (chemotherapy and radiation) prior to definitive surgical treatment, so as to evaluate its effects on the stage by comparing clinical and radiological findings with pathology...
March 2016: Revista do Colégio Brasileiro de Cirurgiões
https://read.qxmd.com/read/23827417/-familiarity-and-perceptions-of-portuguese-cardiologists-concerning-cardiac-magnetic-resonance-and-cardiac-computed-tomography-the-extent-of-the-task-ahead
#16
JOURNAL ARTICLE
António Miguel Ferreira, Nuno Bettencourt, Pedro Matos, Luís Oliveira, Ana G Almeida
INTRODUCTION: Rapid advances in cardiac magnetic resonance (CMR) and cardiac computed tomography angiography (CCTA) pose challenges for practicing physicians in terms of awareness of their indications, contraindications, advantages and pitfalls. METHODS: We conducted a nationwide online survey assessing the familiarity, perceptions and patterns of use concerning these imaging modalities based on a questionnaire sent to all physician members of the Portuguese Society of Cardiology...
July 2013: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://read.qxmd.com/read/23199823/-consensus-document-on-coding-of-cardiac-magnetic-resonance-examinations-in-portugal
#17
JOURNAL ARTICLE
António Miguel Ferreira, Ana G Almeida, Luís Oliveira, Nuno Bettencourt, Hugo Marques, Pedro Matos, João Abecasis, João Abreu, Francisco Alpendurada, Ana Botelho, Paula Campos, Susana Castela, Damião Cunha, Paulo Donato, Maria João Ferreira, Luís Rocha Lopes, Teresa Pinho, Isabel Sá, Carla Saraiva, Nuno Jalles Tavares, Raquel Themudo
One of the obstacles to more frequent and appropriate use of cardiac magnetic resonance (CMR) in Portugal has been the lack of specific codes that accurately describe these examinations as they are currently performed. In this consensus document, recommendations are made for updating and standardizing CMR codes in Portugal. Guidance on which techniques and codes should be used in the most common clinical scenarios is also provided.
January 2013: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
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