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Ultrasound contrast

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https://www.readbyqxmd.com/read/28342532/shear-scaling-based-approach-for-irreversible-energy-loss-estimation-in-stenotic-aortic-flow-an-in-vitro-study
#1
Utku Gülan, Christian Binter, Sebastian Kozerke, Markus Holzner
Today, the functional and risk assessment of stenosed arteries is mostly based on ultrasound Doppler blood flow velocity measurements or catheter pressure measurements, which rely on several assumptions. Alternatively, blood velocity including turbulent kinetic energy (TKE) may be measured using MRI. The aim of the present study is to validate a TKE-based approach that relies on the fact that turbulence production is dominated by the flow's shear to determine the total irreversible energy loss from MRI scans...
March 12, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28338071/phase-transition-nanodroplets-for-real-time-photoacoustic-ultrasound-dual-modality-imaging-and-photothermal-therapy-of-sentinel-lymph-node-in-breast-cancer
#2
Lu Yang, Juan Cheng, Yuli Chen, Shengjie Yu, Fengqiu Liu, Yang Sun, Yu Chen, Haitao Ran
Pathological status of lymph nodes (LNs) plays a critical role in staging and treatment for the patients with breast cancer. Sentinel lymph node biopsy has become the standard method in determining pathological status of axillary LNs. Therefore, the determination of sentinel lymph nodes (SLNs) and therapy of metastatic LNs are highly desirable in clinic. Herein, an unprecedented carbon nanoparticles (CNs)-incorporated liquid-gas phase-transition nanodroplets (CNPs) with strong near-infrared (NIR) absorption, good biocompatibility, excellent photoacoustic (PA) and ultrasound (US) contrast, and high photothermal-conversion efficiency are reported in this study...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28337353/gastric-duplication-a-rare-cause-of-recurrent-vomiting
#3
Brahmananda Koduri, Katie McHale, Christina Yost, Michael H Goodman, Dennis Hoelzer
Vomiting is a physical finding that can occur at any age but presents the greatest challenge when it is recurrent in a child. The etiology is varied (Sieunarine and Manmohansingh, 1989; Suzuki, 1982), and recurrent vomiting can be a symptom of life threatening medical or surgical emergencies. Early recognition is mandatory for preventing delay in management and potential complications. Gastric duplication is rare and mostly diagnosed in infancy with only a few cases documented in the medical literature presenting in childhood...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/28337285/preclinical-and-clinical-evaluation-of-the-liver-tumor-irreversible-electroporation-by-magnetic-resonance-imaging
#4
Matteo Figini, Xifu Wang, Tianchu Lyu, Zhanliang Su, Daniele Procissi, Vahid Yaghmai, Andrew C Larson, Zhuoli Zhang
Irreversible electroporation (IRE) is a relatively new technique for tumor ablation. It has shown promising results in difficult cases where surgery is not recommended and delicate anatomic structures are present near or within the tumor. Currently, liver cancer is one of the most common targets for IRE treatment. Pre-operative and post-operative imaging has a key role in IRE procedures and research studies. Although ultrasound is usually the first choice, especially for intra-operative guidance, magnetic resonance imaging (MRI) plays an important role in the visualization and characterization of tumor before and after IRE in clinical and preclinical studies...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28336398/modulation-of-mammary-tumor-vascularization-by-mast-cells-ultrasonographic-and-histopathological-approaches
#5
Ana I Faustino-Rocha, Adelina Gama, Paula A Oliveira, Katrien Vanderperren, Jimmy H Saunders, Maria J Pires, Rita Ferreira, Mário Ginja
AIMS: The inhibition of mast cells' degranulation may be an approach to prevent the formation of new vessels during the mammary carcinogenesis. MATERIALS AND METHODS: Female Sprague-Dawley rats were randomly divided into five experimental groups. Mammary tumors were induced by intraperitoneal injection of N-methyl-N-nitrosourea (MNU). Animals from group II were treated with ketotifen for 18weeks immediately after the MNU administration, while animals from group III only received the ketotifen after the development of the first mammary tumor...
March 20, 2017: Life Sciences
https://www.readbyqxmd.com/read/28335472/detecting-breast-cancer-with-a-dual-modality-device
#6
Kamila Padia, Tania S Douglas, Lydia L Cairncross, Roland V Baasch, Christopher L Vaughan
Although mammography has been the gold standard for the early detection of breast cancer, if a woman has dense breast tissue, a false negative diagnosis may occur. Breast ultrasound, whether hand-held or automated, is a useful adjunct to mammography but adds extra time and cost. The primary aim was to demonstrate that our second-generation Aceso system, which combines full-field digital mammography (FFDM) and automated breast ultrasound (ABUS) in a single platform, is able to produce improved quality images that provide clinically meaningful results...
March 18, 2017: Diagnostics
https://www.readbyqxmd.com/read/28333964/optimizing-ultrasound-molecular-imaging-of-secreted-frizzled-related-protein-2-expression-in-angiosarcoma
#7
James K Tsuruta, Nicholas P Schaub, Juan D Rojas, Jason Streeter, Nancy Klauber-DeMore, Paul Dayton
Secreted frizzled related protein 2 (SFRP2) is a tumor endothelial marker expressed in angiosarcoma. Previously, we showed ultrasound molecular imaging with SFRP2-targeted contrast increased average video pixel intensity (VI) of angiosarcoma vessels by 2.2 ± 0.6 VI versus streptavidin contrast. We hypothesized that redesigning our contrast agents would increase imaging performance. Improved molecular imaging reagents were created by combining NeutrAvidin™-functionalized microbubbles with biotinylated SFRP2 or IgY control antibodies...
2017: PloS One
https://www.readbyqxmd.com/read/28333625/real-time-nonlocal-means-based-despeckling
#8
Lars H Breivik, Sten Roar Snare, Erik N Steen, Anne H Solberg
In this paper we propose a multiscale nonlocal means based despeckling method for medical ultrasound. The multiscale approach leads to large computational savings and improves despeckling results over single scale iterative approaches. We present two variants of the method. The first, denoted multiscale nonlocal means, yields uniform robust filtering of speckle both in structured and homogeneous regions. The second, denoted unnormalized multiscale nonlocal means, is more conservative in regions of structure assuring minimal disruption of salient image details...
March 22, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28333624/a-fast-and-robust-beamspace-adaptive-beamformer-for-medical-ultrasound-imaging
#9
Ali Mohades Deylami, Babak Mohammadzadeh Asl
Minimum variance beamformer (MVB) increases the resolution and contrast of medical ultrasound imaging compared to non-adaptive beamformers. These advantages come at the expense of high computational complexity that prevents this adaptive beamformer to be applied in a real-time imaging system. A new beamspace based on discrete cosine transform (DCT) is proposed in which the medical ultrasound signals can be represented with less dimensions compared to the standard beamspace. This is because of symmetric beampattern of the beams in the proposed beamspace compared to the asymmetric ones in the standard beamspace...
March 21, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28332442/ultrasound-imaging-in-the-diagnosis-of-large-vessel-vasculitis
#10
Michael Czihal, Christian Lottspeich, Ulrich Hoffmann
Nowadays noninvasive vascular imaging has an important role in the diagnostic work-up of the large vessel vasculitides (LVV), most importantly giant cell arteritis (GCA) and Takayasu arteritis. Among the imaging modalities available, ultrasound (US) has several important advantages, including low costs, rapid and repetitive availability without exposure to radiation, and high spatial resolution for assessment of large and medium-sized arteries. Therefore, US can be regarded the first line imaging method in suspected LVV...
March 23, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28331942/contrast-enhanced-ultrasound-for-differentiating-benign-from-malignant-solid-small-renal-masses-comparison-with-contrast-enhanced-ct
#11
Shu-Ping Wei, Chao-Li Xu, Qing Zhang, Qi-Rui Zhang, Yan-E Zhao, Peng-Fei Huang, Ying-Dong Xie, Chang-Sheng Zhou, Fu-Li Tian, Bin Yang
PURPOSE: The study aimed to compare the diagnostic efficiency of contrast-enhanced ultrasound (CEUS) with that of contrast-enhanced computed tomography (CECT) in the evaluation of benign and malignant small renal masses (SRMs) (<4 cm) confirmed by pathology. METHODS: A total of 118 patients with 118 renal masses smaller than 4 cm diagnosed by both CEUS and CECT were enrolled in this study, including 25 benign lesions and 93 malignant lesions. All lesions were confirmed by histopathologic diagnosis after surgical resection...
March 22, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28330415/novel-detection-of-placental-insufficiency-by-magnetic-resonance-imaging-in-the-nonhuman-primate
#12
Jamie O Lo, Victoria H J Roberts, Matthias C Schabel, Xiaojie Wang, Terry K Morgan, Zheng Liu, Colin Studholme, Christopher D Kroenke, Antonio E Frias
The placenta is a vital organ necessary for healthy fetal development. Placental insufficiency creates an in utero environment where the fetus is at risk of insufficient oxygen or nutrient exchange. This is primarily caused by impairment of either maternal or fetal circulation or vascular thrombosis such as placental infarction. As a result of placental dysfunction, affected fetuses may be growth restricted, neurologically impaired, and at risk of increased morbidity and mortality. In a cohort of 4 pregnant Rhesus macaques, we describe antenatal detection of naturally occurring intrauterine growth restriction (IUGR) and aberrant fetal neurodevelopment in 1 animal...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28329905/-acute-abdominal-pain
#13
Peter Becker, Knut A Böttcher, Dieter Schilling
Acute abdominal pain is a potentially life-threatening condition that requires a concise and quick workup. Patient history, physical examination and laboratory studies help to establish a working diagnosis. If abdominal Ultrasound is not conclusive, contrast-enhanced Computertomography should be performed. Every patient should be treated aggressively for pain control and fluid substitution independent of the diagnostic workflow. In cases of severe disease, initiation of broad spectrum antibiotic therapy should be considered early...
March 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28329875/american-college-of-radiology-contrast-enhanced-ultrasound-liver-imaging-reporting-and-data-system-ceus-li-rads-for-the-diagnosis-of-hepatocellular-carcinoma-a-pictorial-essay
#14
Fabio Piscaglia, Stephanie R Wilson, Andrej Lyshchik, David Cosgrove, Christoph F Dietrich, Hyun-Jung Jang, Tae Kyoung Kim, Veronica Salvatore, Juergen Karl Willmann, Claude B Sirlin, Yuko Kono
No abstract text is available yet for this article.
March 22, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/28328504/blocked-elements-in-1-d-and-2-d-arrays-part-i-detection-and-basic-compensation-on-simulated-and-i-in-vivo-i-targets
#15
Marko Jakovljevic, Gianmarco Pinton, Jeremy J Dahl, Gregg Trahey
During a transcostal ultrasound scan, ribs and other highly attenuating and/or reflective tissue structures can block parts of the array. Blocked elements tend to limit the acoustic window and impede visualization of structures of interest. Here, we demonstrate a method to detect blocked elements and we measure the loss of image quality they introduce in simulation and in vivo. We utilize a fullwave simulation tool and a clinical ultrasound scanner to obtain element signals from fullysampled matrix arrays during simulated and in vivo transcostal liver scans, respectively...
March 16, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28327582/real-time-sentinel-lymph-node-biopsy-guidance-using-combined-ultrasound-photoacoustic-fluorescence-imaging-in-vivo-proof-of-principle-and-validation-with-nodal-obstruction
#16
Jeeun Kang, Jin Ho Chang, Sun Mi Kim, Hak Jong Lee, Haemin Kim, Brian C Wilson, Tai-Kyong Song
Precise sentinel lymph node (SLN) identification is crucial not only for accurate diagnosis of micro-metastases at an early stage of cancer progression but also for reducing the number of SLN biopsies (SLNB) to minimize their severe side effects. Furthermore, it is desirable that an SLNB guidance should be as safe as possible in routine clinical use. Although there are currently various SLNB guidance methods for pre-operative or intra-operative assessment, none are ideal. We propose a real-time SLNB guidance method using contrast-enhanced tri-modal images (i...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327075/magnetic-nanobubbles-with-potential-for-targeted-drug-delivery-and-trimodal-imaging-in-breast-cancer-an-in-vitro-study
#17
Weixiang Song, Yindeng Luo, Yajing Zhao, Xinjie Liu, Jiannong Zhao, Jie Luo, Qunxia Zhang, Haitao Ran, Zhigang Wang, Dajing Guo
AIM: The aim of this study was to improve tumor-targeted therapy for breast cancer by designing magnetic nanobubbles with the potential for targeted drug delivery and multimodal imaging. MATERIALS & METHODS: Herceptin-decorated and ultrasmall superparamagnetic iron oxide (USPIO)/paclitaxel (PTX)-embedded nanobubbles (PTX-USPIO-HER-NBs) were manufactured by combining a modified double-emulsion evaporation process with carbodiimide technique. PTX-USPIO-HER-NBs were examined for characterization, specific cell-targeting ability and multimodal imaging...
March 13, 2017: Nanomedicine
https://www.readbyqxmd.com/read/28322902/negative-multi-parametric-mri-of-the-prostate-predicts-absence-of-clinically-significant-prostate-cancer-on-12-core-template-prostate-biopsy
#18
Amanda J Lu, Jamil S Syed, Kevin A Nguyen, Cayce B Nawaf, James Rosoff, Michael Spektor, Angelique Levi, Peter A Humphrey, Jeffrey C Weinreb, Peter G Schulam, Preston C Sprenkle
OBJECTIVE: To determine the negative predictive value of multiparametric-MRI (mpMRI), we evaluated the frequency of prostate cancer detection by 12-core template mapping biopsy in men whose mpMRI showed no suspicious regions. METHODS: 670 patients underwent mpMRI followed by transrectal ultrasound-(TRUS) guided systematic prostate biopsy from December 2012 to June 2016. Of this cohort, 100 patients had a negative mpMRI. mpMRI imaging sequences included T2-weighted, diffusion-weighted imaging, and dynamic contrast enhancement sequences...
March 16, 2017: Urology
https://www.readbyqxmd.com/read/28321928/eus-evaluation-for-pancreatic-cysts-necessity-or-overkill
#19
REVIEW
Nonthalee Pausawasdi, Thawee Ratanachu-Ek
Incidental pancreatic cysts have been gradually more recognized in clinical practice due to an increased use of transabdominal ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI). These lesions consist of inflammatory cysts (pseudocysts) and pancreatic cystic neoplasms (PCNs) which have been classified as benign, pre-malignant and malignant. The diagnosis and management strategy of incidentally discovered pancreatic cysts can be challenging as the majority of them are PCNs and CT or MRI alone may not be sufficient to provide an accurate diagnosis...
March 21, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28320658/compressed-sensing-based-synthetic-transmit-aperture-imaging-validation-in-a-convex-array-configuration
#20
Jing Liu, Qiong He, Jianwen Luo
According to the linear acoustic theory, the channel data of a plane wave emitted by a linear array is a linear combination of the full dataset of synthetic transmit aperture (STA). Combining this relationship with compressed sensing (CS), a novel CS based ultrasound beamforming strategy, named compressed sensing based synthetic transmit aperture (CS-STA), was previously proposed to increase the frame rate of ultrasound imaging without sacrificing the image quality for a linear array. In this paper, assuming linear transfer function of pulse-echo ultrasound system, we derived and applied the theory of CS-STA for a slightly curved array and validated CS-STA in a convex array configuration...
March 14, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
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