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https://www.readbyqxmd.com/read/27935642/long-term-health-related-quality-of-life-hrqol-in-living-liver-donors-a-south-asian-experience
#1
P Thomas Cherian, Ashish Kumar Mishra, Sm Faisal Mahmood, Mohan Sathyanarayanan, Ravichandra Raya, Venugopal Kota, Mohamed S Rela
: The aim of this study was to evaluate long-term health related quality of life(HRQOL), changes in lifestyle and complications in living liver donors at a single transplant center from southern India. METHODS: 64 consecutive living liver donors from 2008-2011 were evaluated.46 out of 64 donors completed the short form 36(SF-36) via telephonic interviews or clinic consultations. Mean follow up was 48 months (range 37-84 months). RESULTS: There was no mortality in the donors evaluated...
December 9, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27933585/effect-of-rheology-and-poloxamers-properties-on-release-of-drugs-from-silicon-dioxide-gel-filled-hard-gelatin-capsules-a-further-enhancement-of-viability-of-liquid-semisolid-matrix-technology
#2
Misbah Sultana, Mobashar Ahmad Butt, Tariq Saeed, Rizwan Mahmood, Saeed Ul Hassan, Khalid Hussain, Syed Atif Raza, Muhammad Ahsan, Nadeem Irfan Bukhari
The liquid and semisolid matrix technology, filling liquids, semi-solids and gels in hard gelatin capsule are promising, thus, there is a need of enhanced research interest in the technology. Therefore, the present study was aimed to investigate isoniazid (freely soluble) and metronidazole (slightly soluble) gels filled in hard gelatin capsules for the effect of poloxamers of different viscosities on release of the drugs. Gel of each drug (10% w/w, particle size 180-250 μm), prepared by mixing poloxamer and 8% w/w hydrophilic silicon dioxide (Aerosil® A200), was assessed for rheology, dispersion stability and release profile...
December 8, 2016: AAPS PharmSciTech
https://www.readbyqxmd.com/read/27931169/a-mouse-model-of-bilateral-cervical-contusion-compression-spinal-cord-injury
#3
Nicole Forgione, Mahmood Chamankhah, Michael Fehlings
Cervical spinal cord injury (cSCI) occurs in over half of all cases of traumatic SCI, yet we lack therapies that can generate significant functional recovery in these patients. The development of animal models of cSCI will aid in the pre-clinical assessment of therapies and in understanding basic pathophysiological mechanisms. Here we describe a clinically relevant model of cervical contusion-compression injury in the mouse. Using a modified aneurism clip we generated a bilateral, incomplete injury that mimics contusion-compression injuries most commonly seen in humans...
December 8, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27929386/higher-levels-of-aflatoxin-m1-contamination-and-poorer-composition-of-milk-supplied-by-informal-milk-marketing-chains-in-pakistan
#4
Naveed Aslam, Muhammad Yasin Tipu, Muhammad Ishaq, Ann Cowling, David McGill, Hassan Mahmood Warriach, Peter Wynn
The present study was conducted to observe the seasonal variation in aflatoxin M1 and nutritional quality of milk along informal marketing chains. Milk samples (485) were collected from three different chains over a period of one year. The average concentrations of aflatoxin M1 during the autumn and monsoon seasons (2.60 and 2.59 ppb) were found to be significantly higher (standard error of the difference, SED = 0.21: p = 0.003) than in the summer (1.93 ppb). The percentage of added water in milk was significantly lower (SED = 1...
December 5, 2016: Toxins
https://www.readbyqxmd.com/read/27929330/differential-relationships-between-social-adversity-and-depressive-symptoms-by-hiv-status-and-racial-ethnic-identity
#5
Timothy J Williamson, Zanjbeel Mahmood, Taylor P Kuhn, April D Thames
OBJECTIVE: Historically marginalized groups are likely to be exposed to social adversity, which predicts important mental health outcomes (e.g., depression). Despite the well-established relationship between adversity and poor health, few studies have examined how adversity differentially predicts mental health among people living with multiple, co-occurring marginalized identities or statuses. The current study fills this gap by examining whether relationships between social adversity and depressive symptoms differed between those living with or without a stigmatized disease (i...
December 8, 2016: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/27928961/darpins-bioengineering-and-its-theranostic-approaches-emerging-trends-in-protein-engineering
#6
Mahmood Rasool, Arif Malik, Mubashir Hussain, Kalsoom A Haq, Kiran Butt, Abdul Basit, Muhammad Imran Naseer, Muhammad Asif, Rozena Shaikh, Mohammad Zahid Mustafa, Qamre Alam, Ghulam Rasool, Waseem Ahmad, Absarul L Haque, Mohammad Amjad Kamal
The therapeutic significance of bioengineering proteins has increased dramatically as a new generation of pharmacological drug with a great potential in medical treatment. Protein engineering has improved the use of new non immunoglobulin affinity proteins. The designed ankyrin repeat proteins abbreviated as DARPins is an example. The molecules have smaller structural size, unlike immunoglobulins, but similar target affinity is of great significance. Such molecules get more binding specificity and greater thermodynamic stability...
December 8, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27928255/analyzing-gensini-score-as-a-semi-continuous-outcome
#7
Homa Kashani, Hojjat Zeraati, Kazem Mohammad, Hamidreza Goodarzynejad, Mahmood Mahmoudi, Saeed Sadeghian, Mohammadali Boroumand
Background: Investigators frequently encounter continuous outcomes with plenty of values clumped at zero called semi-continuous outcomes. The Gensini score, one of the most widely used scoring systems for expressing coronary angiographic results, is of this type. The aim of this study was to apply two statistical approaches based on the categorization and original scale of the Gensini score to simultaneously assess the association between covariates and the presence and severity of coronary artery disease (CAD)...
April 13, 2016: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/27928240/color-stability-of-nanofilled-and-microhybrid-resin-based-composites-following-exposure-to-chlorhexidine-mouthrinses-an-in-vitro-study
#8
Mahmood Khosravi, Behnaz Esmaeili, Forough Nikzad, Soraya Khafri
OBJECTIVES: This study aimed to evaluate the effects of chlorhexidine mouthrinses on color stability of nanofilled and micro-hybrid resin-based composites. MATERIALS AND METHODS: In this in-vitro study, 160 disc-shaped specimens (7x2mm) were fabricated of Filtek Z250 and Filtek Z350XT Enamel (A2 shade). The samples of each group were randomly divided into eight subgroups (n=10). The specimens were incubated in artificial saliva at 37°C for 24 hours. The baseline color values (L*, a*, b*) of each specimen were measured according to CIE LAB system using a reflection spectrophotometer...
March 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/27927168/phosphodiesterases-in-non-neoplastic-appearing-colonic-mucosa-from-patients-with-colorectal-neoplasia
#9
Badar Mahmood, Morten Matthiesen Bach Damm, Thorbjørn Søren Rønn Jensen, Marie Balslev Backe, Mattias Salling Dahllöf, Steen Seier Poulsen, Niels Bindslev, Mark Berner Hansen
BACKGROUND: Intracellular signaling through cyclic nucleotides, both cyclic AMP and cyclic GMP, is altered in colorectal cancer. Accordingly, it is hypothesized that an underlying mechanism for colorectal neoplasia involves altered function of phosphodiesterases (PDEs), which affects cyclic nucleotide degradation. Here we present an approach to evaluate the function of selected cyclic nucleotide-PDEs in colonic endoscopic biopsies from non-neoplastic appearing mucosa. METHODS: Biopsies were obtained from patients with and without colorectal neoplasia...
December 7, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27927142/of-a-different-age
#10
Mahmood F Bhutta
No abstract text is available yet for this article.
December 12, 2016: Medical Journal of Australia
https://www.readbyqxmd.com/read/27926563/truth-in-reporting-how-data-capture-methods-obfuscate-actual-surgical-site-infection-rates-within-a-health-care-network-system
#11
Liliana Bordeianou, Christy E Cauley, Donna Antonelli, Sarah Bird, David Rattner, Matthew Hutter, Sadiqa Mahmood, Deborah Schnipper, Marc Rubin, Ronald Bleday, Pardon Kenney, David Berger
BACKGROUND: Two systems measure surgical site infection rates following colorectal surgeries: the American College of Surgeons National Surgical Quality Improvement Program and the Centers for Disease Control and Prevention National Healthcare Safety Network. The Centers for Medicare & Medicaid Services pay-for-performance initiatives use National Healthcare Safety Network data for hospital comparisons. OBJECTIVE: This study aimed to compare database concordance...
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27924234/a-descriptive-study-of-occupational-health-services-in-self-employed-enterprises-nanoscale-enterprises-shiraz-iran
#12
Mehdi Jahangiri, Akbar Rostamabadi, Parvaneh Yekzamani, Bahare Mahmood Abadi, Fariborz Behbood, Seyyedeh Fatemeh Ahmadi, Zahra Momeni
BACKGROUND: This study was conducted with aim of providing an overview of the current status of occupational health services and identifying the most common harmful agents at workplaces of Iranian self-employed enterprises (Nano-Scale Enterprises). METHODS: A cross-sectional study was performed among a random sample including 1,758 employees engaging in self-employed enterprises with 5 and less employees. RESULTS: Coverage of occupational health surveillance was very poor, annual health examinations were been conducted only for 64 (3...
December 2016: Safety and Health At Work
https://www.readbyqxmd.com/read/27921084/the-prevalence-of-herpes-simplex-virus-type-1-and-2-infection-in-iran-a-meta-analysis
#13
REVIEW
Mina Malary, Ghasem Abedi, Zeinab Hamzehgardeshi, Mahdi Afshari, Mahmood Moosazadeh
BACKGROUND: Seroepidemiologic studies indicate a high prevalence of herpes simplex virus (HSV) infection. This infection leads to ophthalmic, dermatologic, oral, neurologic, vaginal and cervical problems. Different studies have been carried out to estimate the HSV seroprevalence in Iran. Combining the results of these studies would be useful for health policy-making. OBJECTIVE: This study aims to estimate the pooled prevalence of HSV infection using meta-analysis...
October 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27919723/three-dimensional-echocardiographic-assessment-of-coaptation-after-aortic-valve-repair
#14
Trevor Szymanski, Andrew Maslow, Feroze Mahmood, Arun Singh
No abstract text is available yet for this article.
September 28, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27919718/intracardiac-mass-of-unknown-origin
#15
Jayant S Jainandunsing, Jelliffe Jeganathan, Thomas W L Scheeren, Arash Khamooshian, Ehsan Natour, Feroze Mahmood
No abstract text is available yet for this article.
September 16, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27916235/the-rohingya-people-of-myanmar-health-human-rights-and-identity
#16
REVIEW
Syed S Mahmood, Emily Wroe, Arlan Fuller, Jennifer Leaning
The Rohingya people of Myanmar (known as Burma before 1989) were stripped of citizenship in 1982, because they could not meet the requirement of proving their forefathers settled in Burma before 1823, and now account for one in seven of the global population of stateless people. Of the total 1·5 million Rohingya people living in Myanmar and across southeast Asia, only 82 000 have any legal protection obtained through UN-designated refugee status. Since 2012, more than 159 000 people, most of whom are Rohingya, have fled Myanmar in poorly constructed boats for journeys lasting several weeks to neighbouring nations, causing hundreds of deaths...
December 1, 2016: Lancet
https://www.readbyqxmd.com/read/27914965/a-review-on-synthesis-properties-and-applications-of-natural-polymer-based-carrageenan-blends-and-composites
#17
REVIEW
Khalid Mahmood Zia, Shazia Tabasum, Muhammad Nasif, Neelam Sultan, Nosheen Aslam, Aqdas Noreen, Mohammad Zuber
Carrageenan is a natural polysaccharide extracted from edible red seaweeds of Rhodophycea class. It has been used as a viscosity increasing or gelling agent for prolonged and controlled drug release, food, pharmaceuticals and other industries. However, in spite of wide range of applications, carrageenan has some drawbacks and adverse effects on the biological systems, so its modifications with natural and synthetic polymers are carried out. This review article presents different sources and properties of carrageenans with special emphasis on natural polymer based carrageenan blends and composites and their applications in controlled drug delivery system, wound dressing and tissue engineering because of their biodegradability and biocompatibility, food industry as thickening/gelling materials, cosmeceuticals and making polyelectrolyte complexes...
November 30, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27908797/molecular-detection-and-characterization-of-respiratory-syncytial-virus-b-genotypes-circulating-in-pakistani-children
#18
Uzma Bashir, Nadia Nisar, Nayab Mahmood, Muhammad Masroor Alam, Hajra Sadia, Syed Sohail Zahoor Zaidi
Respiratory syncytial virus (RSV) is the major cause of acute lower respiratory tract infections in young children, but very little is known about its epidemiology and circulating genotypes in Pakistan. This study analyzed the epidemiological and molecular characteristics of RSV B genotypes in Pakistani children below 5years with acute respiratory tract infections (ARIs) during three consecutive winter seasons from 2010 to 2013. A total of 1941 samples were analyzed for RSV infection by real time PCR and 24% (472/1941) samples were found positive out of which 22...
November 28, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27907985/effectiveness-of-training-intervention-to-improve-medical-student-s-information-literacy-skills
#19
Mohammadhiwa Abdekhoda, Afsaneh Dehnad, Mahmood Yousefi
This study aimed to assess the efficiency of delivering a 4-month course of "effective literature search" among medical postgraduate students for improving information literacy skills. This was a cross-sectional study in which 90 postgraduate students were randomly selected and participated in 12 training sessions. Effective search strategies were presented and the students' attitude and competency concerning online search were measured by a pre- and post-questionnaires and skill tests. Data were analyzed by SPSS version 16 using t-test...
December 2016: Korean Journal of Medical Education
https://www.readbyqxmd.com/read/27906238/microresonator-stabilized-2%C3%A2-%C3%A2-%C3%AE-m-distributed-feedback-gasb-based-diode-laser
#20
Elijah Dale, Mahmood Bagheri, Andrey B Matsko, Clifford Frez, Wei Liang, Siamak Forouhar, Lute Maleki
We report on the stabilization of a high-power distributed feedback (DFB) semiconductor laser operating at 2.05 μm wavelength, using a crystalline whispering gallery mode microresonator. The laser's frequency noise is measured to be below 100  Hz/Hz<sup>1/2</sup> at Fourier frequencies ranging from 10 Hz to 1 MHz. The instantaneous linewidth of the laser is improved by four orders of magnitude compared with the free-running DFB laser, and is measured to be 15 Hz at 0.1 ms measurement time...
December 1, 2016: Optics Letters
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