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https://www.readbyqxmd.com/read/29150596/forming-a-three-dimensional-porous-organic-network-via-solid-state-explosion-of-organic-single-crystals
#1
Seo-Yoon Bae, Dongwook Kim, Dongbin Shin, Javeed Mahmood, In-Yup Jeon, Sun-Min Jung, Sun-Hee Shin, Seok-Jin Kim, Noejung Park, Myoung Soo Lah, Jong-Beom Baek
Solid-state reaction of organic molecules holds a considerable advantage over liquid-phase processes in the manufacturing industry. However, the research progress in exploring this benefit is largely staggering, which leaves few liquid-phase systems to work with. Here, we show a synthetic protocol for the formation of a three-dimensional porous organic network via solid-state explosion of organic single crystals. The explosive reaction is realized by the Bergman reaction (cycloaromatization) of three enediyne groups on 2,3,6,7,14,15-hexaethynyl-9,10-dihydro-9,10-[1,2]benzenoanthracene...
November 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/29150267/can-memory-exist-outside-of-brain-and-be-transferred-historical-review-issues-ways-forward
#2
Ghulam Abbas, Wajahat Mahmood, Faisal Khan
Learning and memory are among the executive functions attributed to intelligent forms of life. Unfortunately, there is a lack of clear understanding regarding the underlying mechanisms governing these functions. Most of the modern day scientists attribute these functions solely to brain. However, in the latter half of last century, a number of reports suggested existence of extra-cranial memory and potential of its transfer between animals. Some have linked this phenomenon to RNA while others believed that peptides were responsible...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29150046/oxidative-stress-and-dna-damage-in-the-cord-blood-of-preterm-infants
#3
Mahmood Norishadkam, Soudeh Andishmand, Javad Zavar Reza, Mohammad Javad Zare Sakhvidi, Vida Rezae Hachesoo
Preterm birth infants are more susceptible to oxidative stress and aftermaths unwanted outcomes such as DNA damage due to hyperoxic stress. In this study, we compared the DNA strand breaks as one of the results of DNA oxidation in white blood cells, malondialdehyde (oxidative stress marker), catalase and superoxide dismutase activity, and total antioxidant capacity (markers of antioxidant defense) in a cord blood plasma of a group of preterm (n=25) and full term births (n=25). The primary DNA damage and plasma oxidative stress markers were significantly higher in a preterm group (p<0...
December 2017: Mutation Research
https://www.readbyqxmd.com/read/29146829/is-bridging-therapy-still-required-in-stroke-due-to-carotid-artery-terminus-occlusions
#4
Romain Bourcier, Pierre-Louis Alexandre, François Eugène, Béatrice Delasalle-Guyomarch, Benoit Guillon, Basile Kerleroux, Suzana Saleme, Gaultier Marnat, Samy Boucebci, Mahmood Mirza, Jean-Christophe Ferré, Chrysanthi Papagiannaki, Hubert Desal
INTRODUCTION: Studies comparing endovascular stroke treatment using mechanical thrombectomy (MT) with or without prior IV tissue plasminogen activator (tPa) have included only 30% of internal carotid artery terminus occlusions (ICA-O), a known predictor of recanalization failure with IV tPa. OBJECTIVE: To carry out a retrospective multicenter analysis of prospectively collected data of consecutive patients to investigate the impact of intravenous thrombolysis on ICA-O by comparing patients treated with MT alone or bridging therapy (BT)...
November 16, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29146634/knowledge-attitudes-and-intention-regarding-mhealth-in-generation-y-evidence-from-a-population-based-cross-sectional-study-in-chakaria-bangladesh
#5
M Shafiqur Rahman, Syed Hanifi, Fatema Khatun, Mohammad Iqbal, Sabrina Rasheed, Tanvir Ahmed, Shahidul Hoque, Tamanna Sharmin, Nazib-Uz Zaman Khan, Shehrin Shaila Mahmood, Abbas Bhuiya
BACKGROUND AND OBJECTIVES: mHealth offers a new opportunity to ensure access to qualified healthcare providers. Therefore, to better understand its potential in Bangladesh, it is important to understand how young people use mobile phones for healthcare. Here we examine the knowledge, attitudes and intentions to use mHealth services among young population. DESIGN: Population based cross sectional household survey. SETTING AND PARTICIPANTS: A total of 4909 respondents, aged 18 years and above, under the Chakaria Health and Demographic Surveillance System (HDSS) area, were interviewed during the period November 2012 to April 2013...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29146075/persistent-organic-pollutant-emission-via-dust-deposition-throughout-pakistan-spatial-patterns-regional-cycling-and-their-implication-for-human-health-risks
#6
Muhammad Sohail, Syed Ali Musstjab Akber Shah Eqani, Joel Podgorski, Avit Kumar Bhowmik, Adeel Mahmood, Nadeem Ali, Tara Sabo-Attwood, Habib Bokhari, Heqing Shen
In the current study, Persistent Organic Pollutants (POPs) in outdoor dustfall was monitored for the first time along the Indus river system of Pakistan. Among the studied OCPs (ng/g, dry weight), DDTs (0.16-62) were the predominant contaminants identified in deposited dust followed by HCHs (0.1-10.2), HCB (0.09-7.4) and chlordanes (0.1-2.8). The indicative diagnostic ratio for DDTs and HCHs suggested recent emission of DDTs as well as historical emission of both chemicals in regions where they were used for crop protection and malarial control...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29145053/elucidating-the-urban-levels-sources-and-health-risks-of-polycyclic-aromatic-hydrocarbons-pahs-in-pakistan-implications-for-changing-energy-demand
#7
Naima Hamid, Jabir Hussain Syed, Muhammad Junaid, Adeel Mahmood, Jun Li, Gan Zhang, Riffat Naseem Malik
Due to the severe fuel crisis in terms of natural gas, a paradigm shift in fuel combustion (diesel, gasoline, and biomass) may increase the atmospheric emissions and associated health risks in Pakistan. Present study was aimed to investigate the concentration of fugitive PAHs in the environment (outdoor and indoor settings), associated probabilistic health risk assessment in the exposed population, and possible linkage between fuel consumption patterns and PAHs emissions in twin cities (Rawalpindi and Islamabad) of Pakistan...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29143782/sustainable-bio-based-phenol-formaldehyde-resoles-using-hydrolytically-depolymerized-kraft-lignin
#8
Homaira Siddiqui, Nubla Mahmood, Zhongshun Yuan, Ferdinando Crapulli, Luana Dessbesell, Amin Rizkalla, Ajay Ray, Chunbao Charles Xu
In this study bio-based bio-phenol-formaldehyde (BPF) resoles were prepared using hydrolytically depolymerized Kraft lignin (DKL) as bio-phenol to partially substitute phenol. The effects of phenol substitution ratio, weight-average molecular weight (Mw) of DKL and formaldehyde-to-phenol (F/P) ratio were also investigated to find the optimum curing temperature for BPF resoles. The results indicated that DKL with Mw ~ 1200 g/mol provides a curing temperature of less than 180 °C for any substitution level, provided that F/P ratios are controlled...
October 28, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29143242/comparing-reactive-oxygen-species-and-dna-fragmentation-in-semen-samples-of-unexplained-infertile-and-healthy-fertile-men
#9
Zahra Zandieh, Akram Vatannejad, Mahmood Doosti, Sara Zabihzadeh, Mahnaz Haddadi, Leila Bajelan, Batool Rashidi, Saeid Amanpour
BACKGROUND: Male factor infertility has increased to more than 40% during the last decade. About 30% of these couples are diagnosed with unexplained infertility. In fact, reactive oxygen species (ROS), especially superoxide anion (O2(-)·) and hydrogen peroxide (H2O2), play a crucial role in regulation of physiological and pathological processes in spermatozoa. Moreover, since the diagnosis of unexplained infertility just through semen analysis is a matter of much controversy; we aimed to evaluate the levels of ROS and sperm DNA fragmentation in the semen samples of unexplained infertile and fertile control couples...
November 15, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29142652/the-association-between-risk-factors-and-chronic-obstructive-pulmonary-disease-in-canada-a-cross-sectional-study-using-the-2014-canadian-community-health-survey
#10
Selma Osman, Chelsea Ziegler, Randie Gibson, Razi Mahmood, John Moraros
Background: The global prevalence of chronic obstructive pulmonary disease (COPD) is expected to increase and the disease is projected to be the third leading cause of death by the year 2020. The purpose of this study was to measure the prevalence and determine the risk factors for COPD in Canada. Methods: This is a cross-sectional study that uses data from a nationally generalizable survey, the Canadian Community Health Survey, 2014. There were 46,924 respondents aged 35 years or older...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29142496/precipitous-resolution-of-type-a-intramural-hematoma-with-medical-management-in-a-patient-with-metastatic-stage-4-renal-cell-carcinoma
#11
Camilo A Velasquez, Syed Usman Bin Mahmood, Mohammad A Zafar, Adam J Brownstein, Ayman Saeyeldin, Bulat A Ziganshin, John A Elefteriades
Intramural hematoma (IMH) is a variant form of aortic dissection characterized by involvement of the aortic media without the presence of an overt intimal flap. Surgical extirpation is the standard of care for type-A IMH in the Western world. However, a conservative approach with anti-impulse therapy has been advocated especially in Japan as a viable alternative. Here, we report a case of an elderly male patient with a history of metastatic stage 4 renal cell carcinoma who was treated with anti-impulse therapy for an acute type-A IMH...
December 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/29141900/imminent-health-crises-among-the-rohingya-people-of-myanmar
#12
EDITORIAL
Nicola S Pocock, Syed S Mahmood, Cathy Zimmerman, Miriam Orcutt
No abstract text is available yet for this article.
November 15, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29141707/importance-and-contribution-of-community-social-and-healthcare-risk-factors-for-hepatitis-c-infection-in-pakistan
#13
Adam Trickey, Margaret T May, Charlotte Davies, Huma Qureshi, Saeed Hamid, Hassan Mahmood, Quaid Saeed, Matthew Hickman, Nancy Glass, Francisco Averhoff, Peter Vickerman
Pakistan has a high prevalence of hepatitis C virus (HCV) infection, estimated at 4.9% (2,290/46,843) in the 2007 national HCV seroprevalence survey. We used data from this survey to assess the importance of risk factor associations with HCV prevalence in Pakistan. Exposures were grouped as community (going to the barbers, sharing smoking equipment, having an ear/nose piercing, tattoo, or acupuncture), healthcare (ever having hemodialysis, blood transfusion, or ≥ 5 injections in the last year), demographic (marital status and age), and socio-economic (illiterate or laborer)...
October 16, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29139070/mobile-health-application-and-e-health-literacy-opportunities-and-concerns-for-cancer-patients-and-caregivers
#14
Hyunmin Kim, Joy V Goldsmith, Soham Sengupta, Asos Mahmood, M Paige Powell, Jay Bhatt, Cyril F Chang, Soumitra S Bhuyan
Health literacy is critical for cancer patients as they must understand complex procedures or treatment options. Caregivers' health literacy also plays a crucial role in caring for cancer patients. Low health literacy is associated with low adherence to medications, poor health status, and increased health care costs. There is a growing interest in the use of mobile health applications (apps) to improve health literacy. Mobile health apps can empower underserved cancer patients and their caregivers by providing features or functionalities to enhance interactive patient-provider communication and to understand medical information more readily...
November 14, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29138009/human-papillomavirus-hpv-infection-in-females-with-normal-cervical-cytology-genotyping-and-phylogenetic-analysis-among-women-in-punjab-pakistan
#15
Hafsa Aziz, Huma Iqbal, Humera Mahmood, Shazia Fatima, Muhammad Faheem, Areej Abdul Sattar, Sobia Tabassum, Sanum Napper, Syeda Batool, Nuzhat Rasheed
OBJECTIVE: Cervical cancer is the fourth most common cancer in the world, seventh overall with account for an estimated 300,000 annual deaths. HPV is the second most common cause of cervical cancer worldwide. HPV screening is not a common practice in Pakistan. The present study aims to determine the prevalence of HPV and HPV types in females with normal cytology of cervix in Upper and Lower region of Punjab Pakistan and analyze the risk factors for HPV in this region. METHOD: In this study, we performed PCR analysis for 1011 female patients with normal cytology of cervix from various districts in Punjab Province, Pakistan and risk factors for acquisition of HPV were studied...
November 11, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29134513/current-concepts-and-unmet-needs-in-psoriatic-arthritis
#16
Farrouq Mahmood, Laura C Coates, Philip S Helliwell
Psoriatic arthritis is a chronic inflammatory arthritis that is part of the spondyloarthropathy group of rheumatic diseases and has associated co-morbidities. It can present with various clinical manifestations making diagnosis and treatment challenging, resulting in significant disability and reduced quality of life for patients. Whilst there have been advances in understanding the pathogenic mechanisms of the disease which have resulted in targeted therapies, there is still the need for further studies as some patients fail or are intolerant of current therapies...
November 13, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29132177/an-insight-on-silk-protein-sericin-from-processing-to-biomedical-application
#17
Farogh Ahsan, Tarique Mahmood Ansari, Shazia Usmani, Paramdeep Bagga
Silks are naturally occurring polymers that have been used clinically as sutures for hundreds of years. It's so for obtained from insects or worms, silk consists of a filament core protein, termed fibroin, and a glue-like coating made up of sericin proteins. An important component of silk has an extended history of being discarded as a waste in the course of silk processing. The cost of sericin for tissue engineering is underestimated and its capability in using as regenerative remedy has simply began to be explored...
November 13, 2017: Drug Research
https://www.readbyqxmd.com/read/29131997/organochlorine-pesticides-across-the-tributaries-of-river-ravi-pakistan-human-health-risk-assessment-through-dermal-exposure-ecological-risks-source-fingerprints-and-spatio-temporal-distribution
#18
Mujtaba Baqar, Yumna Sadef, Sajid Rashid Ahmad, Adeel Mahmood, Jun Li, Gan Zhang
This study monitored the human health risks through dermal exposure, hazardous risks to ecological integrity, contamination levels, spatio-temporal distribution, and congener specific analysis of organochlorine pesticides (OCPs) across River Ravi and its three northern tributaries (Nullah Bein, Nullah Basanter and Nullah Deg). The residual levels of OCPs isomers were screened for water (n=54) and surface sediment (n=54) samples from twenty seven sampling sites in two alternate seasons (pre-monsoon and post-monsoon)...
November 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29127228/association-between-body-mass-index-and-outcomes-after-percutaneous-coronary-intervention-in-multiethnic-south-east-asian-population-a-retrospective-analysis-of-the-malaysian-national-cardiovascular-disease-database-percutaneous-coronary-intervention-ncvd-pci
#19
Zaid Azhari, Muhammad Dzafir Ismail, Ahmad Syadi Mahmood Zuhdi, Norashikin Md Sari, Imran Zainal Abidin, Wan Azman Wan Ahmad
OBJECTIVE: To examine the relationship between body mass index (BMI) and outcomes after percutaneous coronary intervention (PCI) in a multiethnic South East Asian population. SETTING: Fifteen participating cardiology centres contributed to the Malaysian National Cardiovascular Disease Database-Percutaneous Coronary Intervention (NCVD-PCI) registry. PARTICIPANTS: 28 742 patients from the NCVD-PCI registry who had their first PCI between January 2007 and December 2014 were included...
November 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/29126176/hand-arm-vibration-in-orthopaedic-surgery-a-neglected-risk
#20
F Mahmood, K B Ferguson, J Clarke, K Hill, E B Macdonald, D J M Macdonald
Background: Hand-arm vibration syndrome is an occupational disease caused by exposure to hand-arm transmitted vibration. The Health and Safety Executive has set limits for vibration exposure, including an exposure action value (EAV), where steps should be taken to reduce exposure, and an exposure limit value (ELV), beyond which vibrating equipment must not be used for the rest of the working day. Aims: To measure hand-arm transmitted vibration among orthopaedic surgeons, who routinely use hand-operated saws...
November 6, 2017: Occupational Medicine
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