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Peri-implant disease

E King, R Patel, A Patel, L Addy
Dental implants are seen as a good option for replacing missing teeth. The success and survival rates for implants are very high. Concerns are developing about the problem of peri-implantitis. The reports of its prevalence vary but it is noted that the presence of periodontal disease is a risk factor. The issue of peri-implantitis was raised in the House of Lords in 2014. Complaints relating to implants is on the rise with the General Dental Council. Placement of implants in patients with periodontal disease is not a treatment that should be done without a full periodontal assessment and stabilisation of periodontal disease first...
December 9, 2016: British Dental Journal
Moritz Kebschull, Claudia Hülsmann, Per Hoffmann, Panos N Papapanou
Omics analyses, including the systematic cataloging of messenger RNA and microRNA sequences or DNA methylation patterns in a cell population, organ or tissue sample, are powerful means of generating comprehensive genome-level data sets on complex diseases. We have systematically assessed the transcriptome, miRNome and methylome of gingival tissues from subjects with different diagnostic entities of periodontal disease, and studied the transcriptome of primary cells ex vivo, or in vitro after infection with periodontal pathogens...
2017: Methods in Molecular Biology
Ying Zhou, Hua-Wei Zhang, Feng Tian, Jin-Song Chen, Tian-Wen Han, Ya-Hang Tan, Jia Zhou, Tao Zhang, Jing Jing, Yun-Dai Chen
BACKGROUND: Epicardial adipose tissue (EAT) is significantly associated with the formation and composition of coronary atherosclerotic plaque, cardiac events and the clinical prognosis of coronary heart disease. But, whether increased EAT deposition may affect the incidence of in-stent restenosis (ISR) is currently unclear. This study used coronary computed tomography angiography (CCTA) as a mean to investigate whether increased EAT volume was associated with ISR. METHODS: A total of 364 patients who underwent 64-slice CCTA examination for the evaluation of suspected coronary artery disease, and subsequently underwent percutaneous coronary intervention (PCI) for the first time, and then accepted coronary angiography (CA) follow-up for ISR examination in one year, were retrospectively included in this study...
September 2016: Journal of Geriatric Cardiology: JGC
Indu Lata Kanwar, Abhishek Kumar Sah, Preeti K Suresh
Oral diseases like dental caries and periodontal disease are directly associated with the capability of bacteria to form biofilm. Periodontal diseases have been associated to anaerobic Gram-negative bacteria forming a subgingival plaque (Porphyromonas gingivalis, Actinobacillus, Prevotella and Fusobacterium). Biofilm is a complex bacterial community that is highly resistant to antibiotics and human immunity. Biofilm communities are the causative agents of biological developments such as dental caries, periodontitis, and peri-implantitis, and causing periodontal tissue breakdown...
November 24, 2016: Current Pharmaceutical Design
Tariq Abduljabbar
OBJECTIVE: The aim of the present 6-month follow-up study was to assess the effect of mechanical debridement (MD) with adjunct antimicrobial photodynamic therapy (aPDT) in the treatment of peri-implant diseases in type-2 diabetic smokers and non-smokers. METHODS: Patients were divided into 2 groups: (a) Group-1: type-2 diabetic smokers; and (b) Group-2: type-2 diabetic non-smokers. In both groups, hemoglobin A1c (HbA1c) levels and peri-implant bleeding on probing (BOP) and probing depth (PD) ≥4mm were measured at baseline and after 6 months of follow-up...
November 21, 2016: Photodiagnosis and Photodynamic Therapy
Paolo Vigolo, Stefano Gracis, Fabio Carboncini, Sabrina Mutinelli
PURPOSE: The design of an implant connection that allows prosthetic suprastructures to be attached to implants has long been debated in the dental literature. The goal of this retrospective study was to evaluate the 5-year clinical results for a large number of single implants restored by certified prosthodontists in an attempt to establish whether different clinical outcomes could be detected for external- or internal-connection implants. MATERIALS AND METHODS: All single implants with internal or external connections inserted in 27 private dental practices from January 1, 2003 to December 31, 2007 were evaluated...
November 2016: International Journal of Oral & Maxillofacial Implants
Simon Dingsdag, Stephen Nelson, Nicholas V Coleman
BACKGROUND: Previously, we demonstrated that bacteria reside in apparently healed alveolar bone, using culture and Sanger sequencing techniques. Bacteria in apparently healed alveolar bone may have a role in peri-implantitis and dental implant failure. OBJECTIVE: To compare bacterial communities associated with apical periodontitis, those colonising a failed implant and alveolar bone with reference biofilm samples from healthy teeth. METHODS AND RESULTS: The study consisted of 196 samples collected from 40 patients undergoing routine dental implant insertion or rehabilitation...
2016: Microbial Ecology in Health and Disease
Fernando Suárez-López Del Amo, Ricardo Faria E Almeida, Marco Cicciù, Povilas Daugela, Ausra Ramanauskaite, Nikola Saulacic, Tellervo Tervonen, Hom-Lay Wang, Shan-Huey Yu
INTRODUCTION: The task of Group 3 was to review and update the existing data concerning non-surgical, surgical non-regenerative and surgical regenerative treatment of peri-implantitis. Special interest was paid to the preventive and supporting therapy in case of peri-implantitis. MATERIAL AND METHODS: The main areas of interest were as follows: effect of smoking and history of periodontitis, prosthetic treatment mistakes, excess cement, overloading, general diseases influence on peri-implantitis development...
July 2016: Journal of Oral & Maxillofacial Research
Fernando Suárez-López Del Amo, Shan-Huey Yu, Hom-Lay Wang
OBJECTIVES: The purpose of this paper was to systematically evaluate the effectiveness of non-surgical therapy for the treatment of peri-implant diseases including both, mucositis and peri-implantitis lesions. MATERIAL AND METHODS: An electronic search in two different databases was performed including MEDLINE (PubMed) and EMBASE from 2011 to 2016. Human studies reporting non-surgical treatment of peri-implant mucositis and peri-implantitis with more than 10 implants and at least 6 months follow up published in English language were evaluated...
July 2016: Journal of Oral & Maxillofacial Research
Tolga Fikret Tözüm, Erhan Dursun, Pablo Galindo-Moreno, Gintaras Juodzbalys, Jesús López-Martínez, Francisco O'Valle, Miguel Padial-Molina, Ausra Ramanauskaite
INTRODUCTION: The task of Group 2 was to review and update the existing data concerning clinical and genetic methods of diagnostics of peri-implantitis. Special interest was paid to the peri-implant crevicular fluid (PICF) overview including analysis of enzymes and biomarkers and microbial profiles from implants. MATERIAL AND METHODS: The main areas of interest were as follows: effect of smoking and history of periodontitis, prosthetic treatment mistakes, excess cement, overloading, general diseases influence on peri-implantitis development...
July 2016: Journal of Oral & Maxillofacial Research
Miguel Padial-Molina, Jesús López-Martínez, Francisco O'Valle, Pablo Galindo-Moreno
OBJECTIVES: To describe the microbial profiles of peri-implant diseases and the main detection methods. MATERIAL AND METHODS: A literature search was performed in MEDLINE via PubMed database to identify studies on microbial composition of peri-implant surfaces in humans published in the last 5 years. Studies had to have clear implant status definition for health, peri-implant mucositis and/or peri-implantitis and specifically study microbial composition of the peri-implant sulcus...
July 2016: Journal of Oral & Maxillofacial Research
Erhan Dursun, Tolga Fikret Tözüm
OBJECTIVES: To review the current understanding of the biomarkers and enzymes associated with different forms peri-implant diseases and how their level changes influence the pathogenesis of the inflammatory diseases around dental implants. MATERIAL AND METHODS: An electronic search in two different databases was performed including MEDLINE (PubMed) and EMBASE between 1996 to 2016. Human studies analyse peri-implant crevicular fluid (PICF) biomarker and enzyme levels of implants having peri-implant mucositis and peri-implantitis published in English language, were evaluated...
July 2016: Journal of Oral & Maxillofacial Research
Ausra Ramanauskaite, Gintaras Juodzbalys
OBJECTIVES: To review and summarize the literature concerning peri-implantitis diagnostic parameters and to propose guidelines for peri-implantitis diagnosis. MATERIAL AND METHODS: An electronic literature search was conducted of the MEDLINE (Ovid) and EMBASE databases for articles published between 2011 and 2016. Sequential screening at the title/abstract and full-text levels was performed. Systematic reviews/guidelines of consensus conferences proposing classification or suggesting diagnostic parameters for peri-implantitis in the English language were included...
July 2016: Journal of Oral & Maxillofacial Research
Claudio Stacchi, Francesca Andolsek, Inesa Astramskaite, Federico Berton, Roberto Di Lenarda, Maria Helena Fernandes, Andrea Frassetto, Pedro de Sousa Gomes, Zygimantas Guobis, Ryo Jimbo, Gintaras Juodzbalys, Aiman Khoury, Ricardas Kubilius, Ritva Kuoppala, Teresa Lombardi, Julius Maminskas, Ingrida Pacauskiene, Giuseppe Perinetti, Lukas Poskevicius, Mindaugas Pranskunas, Algirdas Puisys, Aune Raustia
INTRODUCTION: The task of Group 1 was to review and update the existing data concerning aetiology, risk factors and pathogenesis of peri-implantitis. Previous history of periodontitis, poor oral hygiene, smoking and presence of general diseases have been considered among the aetiological risk factors for the onset of peri-implant pathologies, while late dental implant failures are commonly associated with peri-implantitis and/or with the application of incorrect biomechanical forces. Special interest was paid to the bone cells dynamics as part of the pathogenesis of peri-implantitis...
July 2016: Journal of Oral & Maxillofacial Research
Zygimantas Guobis, Ingrida Pacauskiene, Inesa Astramskaite
OBJECTIVES: To systematically review the influence of systemic diseases or medications used in their treatment on the dental implant therapy success. MATERIAL AND METHODS: The search strategy was implemented on the National Library of Medicine database (MEDLINE) (Ovid) and EMBASE electronic databases between January 2006 and January 2016. Human studies with available English articles analysing the relationship between dental implant therapy success and systemic diseases, such as diabetes mellitus, AIDS/HIV, rheumatoid arthritis, osteoporosis, Crohn's disease, cardiovascular diseases, scleroderma, Sjögren's syndrome, lichen planus, ectodermal dysplasia, post-transplantation status, were included in present review according to the PRISMA guidelines...
July 2016: Journal of Oral & Maxillofacial Research
Claudio Stacchi, Federico Berton, Giuseppe Perinetti, Andrea Frassetto, Teresa Lombardi, Aiman Khoury, Francesca Andolsek, Roberto Di Lenarda
OBJECTIVES: The purpose of this review was to evaluate whether history of periodontitis and smoking habits could represent a risk factor for peri-implantitis and implant loss. MATERIAL AND METHODS: This systematic review followed PRISMA guidelines and was registered at the PROSPERO database [registration numbers CRD42016034160 (effect of history of periodontitis) and CRD42016033676 (effect of smoking)]. Broad electronic (MEDLINE) and manual searches were conducted among articles published from January 1(st) 1990 up to December 31(st) 2015, resulting in 49332 records for history of periodontitis and 3199 for smoking habits...
July 2016: Journal of Oral & Maxillofacial Research
Roni Kolerman, Eitan Mijiritsky, Eitan Barnea, Areeje Dabaja, Joseph Nissan, Haim Tal
BACKGROUND: To validate the concept of immediate implant placement and nonfunctional loading for use in the esthetically sensitive anterior maxilla, clinical trials should ideally include objective esthetic criteria. PURPOSE: This study analyzed procedural results as graded by the pink esthetic score and white esthetic score (PES/WES). METHODS: Thirty-nine suitable patients (mean follow-up 44.82 ± 28 months) were evaluated. RESULTS: Thirty-eight implants fulfilled stringent criteria for successful osseointegration: absence of peri-implant radiolucency, implant mobility, suppuration, and pain...
November 2, 2016: Clinical Implant Dentistry and related Research
Yusuke Hamada, Srividya Prabhu, Vanchit John
As implant therapy becomes more commonplace in daily practice, preservation and preparation of edentulous sites are key. Many times, however, implant therapy may not be considered at the time of tooth extraction and additional measures are not taken to conserve the edentulous site. While the healing process in extraction sockets has been well investigated and bone fill can be expected, there are cases where even when clinicians perform thorough debridement of the sockets, connective tissue infiltration into the socket can occur...
2016: Case Reports in Dentistry
Orlando Cipriani, Valentino Vellone, Paolo Arangio, Fabio Della Rocca
This study aims to assess the effectiveness and reliability of a new combined approach to treat the maxillary atrophy and chronic rhinosinusitis (CRS) and other rhino-sinusal pathologies. This 1-step procedure consisting functional endoscopic sinus surgery (FESS) and maxillary sinus-lift with simultaneous implant placement for patients with a severe reabsorbed maxillary bone and sinuses' disease. In case of disventilation and maxillary sinuses flogosis, the mucociliary clearance and physiological ventilation have to be aided, in order to make a safer and predictable sinus-lift surgery...
October 27, 2016: Journal of Craniofacial Surgery
Mor Shlezinger, Yael Houri-Haddad, Shunit Coppenhagen-Glazer, Grégory Resch, Yok-Ai Que, Shaul Beyth, Elisheva Dorfman, Ronen Hazan, Nurit Beyth
Dental diseases are perhaps the most prevalent infection-related diseases in humans. Biofilm is involved in almost every infectious disease compromising oral health, notably caries, periodontal disease, gingivitis, endodontic infections and peri-implantitis. Current therapies of biofilm-derived oral infections lack sensitivity; they are not species-specific and kill pathogenic species as well as commensal species, which are protective against the formation of pathogenic biofilms. Moreover, antibiotics have a limited effect on biofilm and are almost unused in oral diseases...
September 30, 2016: Current Topics in Medicinal Chemistry
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