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Peri-implant disease

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https://www.readbyqxmd.com/read/28733984/implant-treatment-in-pharmacologically-immunosuppressed-liver-transplant-patients-a-prospective-controlled-study
#1
Víctor Paredes, Rosa María López-Pintor, Jesús Torres, Juan Carlos de Vicente, Mariano Sanz, Gonzalo Hernández
OBJECTIVES: The main objective of this prospective study was to evaluate the long-term outcome of implant therapy in liver transplant patients (LTP). The secondary goal was to assess several implant- and patient-dependent variables, such as peri-implantitis (PI), peri-implant mucositis (PIM), bone loss (BL), and immediate postoperative complications. MATERIAL AND METHODS: Two groups, including 16 pharmacologically immunosuppressed LTP and 16 matched controls, received 52 and 54 implants, respectively, between 1999 and 2008...
July 21, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28718012/implant-decontamination-with-phosphoric-acid-during-surgical-peri-implantitis-treatment-a-rct
#2
Diederik F M Hentenaar, Yvonne C M De Waal, Hans Strooker, Henny J A Meijer, Arie-Jan Van Winkelhoff, Gerry M Raghoebar
BACKGROUND: Peri-implantitis is known as an infectious disease that affects the peri-implant soft and hard tissue. Today, scientific literature provides very little evidence for an effective intervention protocol for treatment of peri-implantitis. The aim of the present randomized controlled trial is to evaluate the microbiological and clinical effectiveness of phosphoric acid as a decontaminating agent of the implant surface during surgical peri-implantitis treatment. METHODS: Peri-implantitis lesions were treated with resective surgical treatment aimed at peri-implant granulation tissue removal, bone recontouring, and pocket elimination...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28715944/comparison-of-two-different-techniques-used-for-the-maintenance-ofperi-implant-soft-tissue-health-a-pilot-randomized-clinical-trial
#3
Logien Al Ghazal, Jeffery O'Sullivan, Noel Claffey, Ioannis Polyzois
OBJECTIVES: The aim of this pilot study was to compare the effectiveness of two different methods of debridement on maintaining and improving peri-implant soft tissue health over a period of 12 months. MATERIALS AND METHODS: Twenty adult patients (25 implants) were enrolled in a randomized, single-blinded, parallel group clinical trial. All implants included showed no signs of pathologic bone loss. Patients were scheduled to be reviewed every 3 months over a 12 months period...
July 17, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28710652/comparison-between-inflammation-related-markers-in-peri-implant-crevicular-fluid-and-clinical-parameters-during-osseointegration-in-edentulous-jaws
#4
Amália M Bielemann, Raissa M Marcello-Machado, Fábio Renato Manzolli Leite, Frederico Canato Martinho, Otacílio Luiz Chagas-Júnior, Altair Antoninha Del Bel Cury, Fernanda Faot
OBJECTIVES: The aim of this study is to improve the understanding of interleukin mechanisms during osseointegration to enhance the monitoring of implant failure and success. Clinical parameters, implant stability, and cytokine levels in peri-implant crevicular fluid (PICF) during early bone healing after implant placement were investigated. MATERIAL AND METHODS: Sixty narrow implants were placed in mandible anterior region of 30 edentulous patients (67.23 ± 7...
July 14, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28709835/the-antimicrobial-peptide-human-%C3%AE-defensin-1-potentiates-in-vitro-osteoclastogenesis-via-activation-of-the-p44-42-mitogen-activated-protein-kinases
#5
Anupong Makeudom, Chayarop Supanchart, Pattanin Montreekachon, Sakornrat Khongkhunthian, Thanapat Sastraruji, Julaporn Krisanaprakornkit, Suttichai Krisanaprakornkit
Previous studies have demonstrated increased expression and raised levels of human β-defensin (hBD)-1 in gingival tissue and crevicular fluid of patients with chronic periodontitis and peri-implantitis, oral bone-resorbing diseases caused by enhanced osteoclastogenesis. Therefore, we aimed to investigate the effect of hBD-1 on osteoclast formation and function and to elucidate the involved signaling pathway in vitro. Human peripheral blood mononuclear cells (PBMCs) were first incubated with various doses of hBD-1 and cell viability was assayed by MTT...
July 11, 2017: Peptides
https://www.readbyqxmd.com/read/28682643/yy1-is-required-for-posttranscriptional-stability-of-sox2-and-oct4-proteins
#6
Mary C Wallingford, Jacob Hiller, Kun Zhang, Jesse Mager
Yinyang1 (YY1) participates in protein-DNA, protein-RNA, and protein-protein interactions and regulates developmental processes and disease mechanisms. YY1 interactions regulate a range of important biological functions, including oocyte maturation, epithelial to mesenchymal transition, and vascular endothelial growth factor (VEGF) signaling. We tested the hypothesis that YY1 is required for inner cell mass (ICM) lineage commitment during preimplantation development. In this study, we document gene expression patterns and protein localization of key transcription factors in Yy1 global, tissue-specific, and dsRNA-mediated knockout/down embryos...
July 6, 2017: Cellular Reprogramming
https://www.readbyqxmd.com/read/28681042/biology-of-teeth-and-implants-the-external-environment-biology-of-structures-and-clinical-aspects
#7
F-Michael Eggert, Liran Levin
For the past several thousand years, until development of the titanium dental implant, only a few missing teeth were replaced successfully in a very small number of individuals. Nowadays, placement of dental implants has become sufficiently commonplace that there is a need to interchange information between what we know about periodontal health and disease and what we know about health and disease involving dental implants. This review discusses the similarities and differences between teeth and dental implants with regards to anatomy, biology, physiology, and pathologic processes...
July 4, 2017: Quintessence International
https://www.readbyqxmd.com/read/28598582/outcomes-of-intercalary-prosthetic-reconstruction-for-pathological-diaphyseal-femoral-fractures-secondary-to-metastatic-tumors
#8
Hong-Chao Huang, Yong-Cheng Hu, Deng-Xing Lun, Jun Miao, Feng Wang, Xiong-Gang Yang, Xin-Long Ma
OBJECTIVE: To evaluate the clinical outcomes and complications of segmental prosthetic reconstruction for pathological diaphyseal femoral fractures secondary to metastatic tumors. METHODS: Between 2011 and 2015, we retrospectively evaluated 16 patients (6 men and 10 women; 64.5 ± 11.4 years old at diagnosis) who underwent prosthetic reconstruction after segmental resection of diaphyseal femoral fractures due to metastatic lesions. Visual analog scale (VAS), functional outcomes, implant-related complications, and Mean postoperative Musculoskeletal Tumor Society (MSTS) score for each patient were collected...
May 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28598288/implant-patient-compliance-varies-by-periodontal-treatment-history
#9
Blerina Zeza, Andrea Pilloni, Dimitris N Tatakis, Angelo Mariotti, GianLuca Di Tanna, Claudio Mongardini
BACKGROUND: This retrospective study aimed to assess the compliance to supportive periodontal therapy (SPT) of implant treated patients with different periodontitis history and the possible influence of their compliance on peri-implant marginal bone level. MATERIAL AND METHODS: Dental records of 106 patients treated with at least one dental implant were reviewed. A single operator who did not provide care to the patients recorded the following during the first year of implant function (first year of follow-up), during the first 5 years of follow-up and during the entire follow-up duration: (a) number of recalls; (b) compliance, calculated from registered attendance; (c) periodontal disease history; (d) peri-implant radiographic bone level from most recent examination; and (e) clinical parameters: probing pocket depth (PPD) and bleeding on probing (BOP)...
June 9, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28556531/effects-of-uncontrolled-periodontitis-on-marginal-bone-alterations-around-implants-a-case-control-study
#10
Xin Wang, Lei Qin, Chi Lei, Yu Li, Dehua Li
BACKGROUND: The hypothesis of bacterial infection initiating marginal bone loss around dental implant in analogy with natural tooth is still in debate. PURPOSE: The aim of this retrospective study was to investigate the effects of uncontrolled periodontitis on marginal bone alterations around implants compared with the periodontal health group at a mean follow-up of at least 6 years. MATERIALS AND METHODS: Thirty consecutive uncontrolled periodontally compromised patients (PCP) and 30 periodontally healthy patients (PHP), with a total of 96 Straumann implants (PCP = 55, PHP = 41) were matched for age, gender, smoking, and implant characteristics...
May 29, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28548886/association-of-preventive-maintenance-therapy-compliance-and-peri-implant-diseases-a-cross-sectional-study
#11
Alberto Monje, Hom-Lay Wang, José Nart
AIM: This study was aimed at investigating the association between peri-implant maintenance therapy (PIMT) and the frequency of peri-implant diseases, and to further identify the factors that contribute to failure of PIMT compliance. MATERIAL AND METHODS: A cross-sectional study on healthy partial edentulous patients was conducted. These were grouped in the following categories according to the PIMT compliance: regular compliers (RC) (≥2 PIMT/year), erratic compliers (EC) (<2 PIMT/year), and non-compliers (NC) (0 PIMT/year)...
May 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28548884/patient-centered-perspectives-and-understanding-of-peri-implantitis
#12
Angel Insua, Alberto Monje, Hom-Lay Wang, Marita Inglehart
BACKGROUND: Daily-basis patients have uncertain understanding about dental implant therapy and its complications. Therefore, an assessment of the level of knowledge, awareness and attitudes on peri-implantitis, evaluation of information provided by the dentist/specialist that performed the treatment and assessment of perceptions, level of satisfaction and impact in the quality of life of the patients were carried out. MATERIAL AND METHODS: Patients with implant therapy and currently undergoing peri-implant implant maintenance therapy were recruited...
May 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28512358/delayed-epidural-transplantation-of-human-induced-pluripotent-stem-cell-derived-neural-progenitors-enhances-functional-recovery-after-stroke
#13
I-Hui Lee, Shiang-Suo Huang, Ching-Yu Chuang, Ko-Hsun Liao, Li-Hsin Chang, Chia-Chi Chuang, Yu-Shih Su, Hung-Jui Lin, Jui-Yu Hsieh, Shu-Han Su, Oscar Kuang-Sheng Lee, Hung-Chih Kuo
Induced pluripotent stem cell-derived neural progenitor cells (iPSC-NPCs) are a promising source of tailor-made cell therapy for neurological diseases. However, major obstacles to clinical use still exist. To circumvent complications related to intracerebral administration, we implanted human iPSC-NPCs epidurally over the peri-infarct cortex 7 days after permanent middle cerebral artery occlusion in adult rats. Compared to controls, cell-treated rats showed significant improvements in paretic forelimb usage and grip strength from 10 days post-transplantation (dpt) onwards, as well as reductions in lesion volumes, inflammatory infiltration and astrogliosis at 21 dpt...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28497021/understanding-rare-adverse-sequelae-of-breast-implants-anaplastic-large-cell-lymphoma-late-seromas-and-double-capsules
#14
REVIEW
Mark W Clemens, Maurizio Bruno Nava, Nicola Rocco, Roberto N Miranda
Breast implant-associated anaplastic large cell lymphoma (BI-ALCL) is a distinct type of T-cell lymphoma arising around breast implants. The United States FDA recently updated the 2011 safety communication, warning that women with breast implants may have a very low risk of developing ALCL adjacent to a breast implant. According to the World Health Organization, BI-LCL is not a breast cancer or cancer of the breast tissue; it is a lymphoma, a cancer of immune cells. BI-ALCL is highly curable in the majority of patients...
April 2017: Gland Surgery
https://www.readbyqxmd.com/read/28495214/lesson-learned-with-the-use-of-iliac-branch-devices-single-centre-10-year-experience-in-157-consecutive-procedures
#15
G Simonte, G Parlani, L Farchioni, G Isernia, E Cieri, M Lenti, P Cao, F Verzini
OBJECTIVE/BACKGROUND: Absence of an adequate iliac seal rarely represents an absolute contraindication to endovascular abdominal aortic aneurysm repair. Iliac branch devices (IBD) are increasingly used in patients with extensive aorto-iliac aneurysmal disease, but few data are available on the long-term results of these procedures. METHODS: Between 2006 and 2016, 157 consecutive IBD procedures performed at a single centre were entered into a prospective database...
May 7, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28480634/does-osteoporosis-influence-the-marginal-peri-implant-bone-level-in-female-patients-a-cross-sectional-study-in-a-matched-collective
#16
Florian Wagner, Krisztian Schuder, Markus Hof, Simone Heuberer, Rudolf Seemann, Gabriella Dvorak
BACKGROUND/PURPOSE: Osteoporosis, being a homeostatic imbalance, affects the remodeling of bone. Whether this catabolic bone disease influences peri-implant marginal bone remodeling remains unknown so far. The purpose of this study was to evaluate the influence of osteoporosis on peri-implant marginal bone loss (MBL) in postmenopausal women. MATERIALS AND METHODS: In a matched collective, radiographic peri-implant bone level (at baseline and at follow-up examinations) was compared in healthy and osteoporotic women...
May 8, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28472599/peri-prosthetic-knee-infection-management-spacers-loaded-with-two-or-three-antibiotic-agents
#17
David Joaquin Ortola, Domenico Fenga, Sandra Marcellino, Massimiliano Rosi, Francesco Centofanti, Michele Attilio Rosa
BACKGROUND: The purpose of this work was to compare pre-made antibiotic-loaded spacers with two commercially available antibiotic agents and custom-made cements with three antibiotic agents added. We evaluated: (a) the validity of our procedures, (b) the control of the rate of infection in the long term, (c) complications, and (d) quality of life and patient satisfaction. METHODS: A retrospective cohort study was performed on 112 consecutively treated patients between January 2010 and December 2013; 56 patients were treated with a pre-formed cement spacer (clindamycin + gentamicin), and 56 patients were treated with a spacer loaded with three antibiotic agents (clindamycin + gentamicin + vancomycin)...
July 2017: Surgical Infections
https://www.readbyqxmd.com/read/28458811/cochlear-impairment-and-autoimmune-ear-disorder-in-a-patient-with-breast-cancer
#18
Alessandra Fioretti, Vittoria Di Rubbo, Giorgia Peri, Elisa Vitti, Sara Cisternino, Theodoros Varakliotis, Alberto Eibenstein
The purpose of this study was to consider the possible role of autoimmune diseases and paraneoplastic syndrome in the genesis of tinnitus. The incidence of autoimmune inner ear disease (AIED) is rare, accounting for <1% of all cases of hearing impairment and dizziness. In presence of auditory and vestibular deficit in oncological patients, a paraneoplastic syndrome with cochleovestibulopathy should be considered. We described a 50-year-old Caucasian woman came to our attention with complaints of severe disabling bilateral tinnitus (Tinnitus Handicap Inventory, THI: 96), ear fullness and headache...
February 1, 2017: Audiology Research
https://www.readbyqxmd.com/read/28453869/non-surgical-treatment-of-peri-implant-mucositis-and-peri-implantitis-at-two-piece-zirconium-implants-a-clinical-follow-up-observation-after-up-to-3%C3%A2-years
#19
Gordon John, Jürgen Becker, Andrea Schmucker, Frank Schwarz
OBJECTIVES: To assess the long-term clinical outcomes following non-surgical therapy of peri-implant diseases at two-piece zirconium implants. MATERIAL AND METHODS: A total of 27 patients suffering from either (i) peri-implant mucositis (n = 24 implants), or (ii) peri-implantitis (n = 16 implants) completed a mean follow-up period of 32.8 ± 2.85 months (median: 34 months). The initial treatment procedures included (i) mechanical debridement + local antiseptic therapy using chlorhexidine digluconate (MD + CXH), or (ii) Er:YAG laser monotherapy (ERL)...
April 28, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28440740/biomarkers-and-bacteria-around-implants-and-natural-teeth-in-the-same-individuals
#20
Önder Gürlek, Pınar Gümüş, Christopher J Nile, David F Lappin, Nurcan Buduneli
AIM: This cross-sectional study assessed cytokine levels in peri-implant crevicular fluid (PICF)/ gingival crevicular fluid (GCF) and a selection of subgingival/submucosal plaque bacteria from clinically healthy or diseased sites in the same individuals. MATERIAL AND METHODS: Samples from 97 implants/teeth (58 implants: 19 healthy, 20 mucositis, 19 peri-implantitis; 39 natural teeth: 19 healthy, 12 gingivitis, 8 periodontitis) in 15 systemically healthy patients were investigated by immunoassay, real-time PCR...
April 25, 2017: Journal of Periodontology
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