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Peri-implantitis

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https://www.readbyqxmd.com/read/28076651/controlled-release-of-chlorhexidine-from-a-mesoporous-silica-containing-macroporous-titanium-dental-implant-prevents-microbial-biofilm-formation
#1
K De Cremer, A Braem, E Gerits, K De Brucker, K Vandamme, J A Martens, J Michiels, J Vleugels, B P Cammue, K Thevissen
Roughened surfaces are increasingly being used for dental implant applications as the enlarged contact area improves bone cell anchorage, thereby facilitating osseointegration. However, the additional surface area also entails a higher risk for the development of biofilm associated infections, an etiologic factor for many dental ailments, including peri-implantitis. To overcome this problem, we designed a dental implant composed of a porous titanium-silica (Ti/SiO2) composite material and containing an internal reservoir that can be loaded with antimicrobial compounds...
January 11, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28063235/a-critical-role-for-adiponectin-mediated-development-of-endometrial-luminal-epithelial-cells-during-the-peri-implantation-period-of-pregnancy
#2
Whasun Lim, Myung Jin Choi, Hyocheol Bae, Fuller W Bazer, Gwonhwa Song
Adiponectin is one of the adipokines in the collagen superfamily. It is secreted primarily by white adipocytes and influences reproductive processes including ovarian and uterine functions. Adiponectin regulates energy homeostasis, insulin sensitivity and is anti-inflammatory in various tissues. Its receptors (ADIPOR1 and ADIPOR2) are widely expressed in mammalian tissues, including porcine conceptuses and endometrial during the estrous cycle and peri-implantation period of pregnancy. However, regulatory effects of adiponectin on endometrial epithelial cells are unknown...
January 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28059080/scaling-of-titanium-implants-entrains-inflammation-induced-osteolysis
#3
Michal Eger, Nir Sterer, Tamar Liron, David Kohavi, Yankel Gabet
With millions of new dental and orthopedic implants inserted annually, periprosthetic osteolysis becomes a major concern. In dentistry, peri-implantitis management includes cleaning using ultrasonic scaling. We examined whether ultrasonic scaling releases titanium particles and induces inflammation and osteolysis. Titanium discs with machined, sandblasted/acid-etched and sandblasted surfaces were subjected to ultrasonic scaling and we physically and chemically characterized the released particles. These particles induced a severe inflammatory response in macrophages and stimulated osteoclastogenesis...
January 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28054383/comparison-between-two-antimicrobial-protocols-with-or-without-guided-bone-regeneration-in-the-treatment-of-peri-implantitis-a-histomorphometric-study-in-dogs
#4
Umberto Demoner Ramos, Flavia Adelino Suaid, Ulf M E Wikesjö, Cristiano Susin, Mario Taba, Arthur Belém Novaes
OBJECTIVES: This study used a dog model to evaluate two antimicrobial protocols with or without guided bone regeneration (GBR) in the surgical reconstruction of peri-implantitis defects. MATERIAL AND METHODS: Eight beagle dogs subject to ligature-induced peri-implantitis were used. The animals either received antimicrobial photodynamic therapy or topical tetracycline hydrochloride combined with GBR or as stand-alone surgical interventions. Block biopsies of the defect sites for histological analysis were obtained at euthanasia, 12 weeks postsurgery...
January 5, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28053913/corrigendum-microbiological-and-clinical-effects-of-enamel-matrix-derivative-and-sustained-release-micro-spherical-minocycline-application-as-an-adjunct-to-non-surgical-therapy-in-peri-implant-mucosal-inflammation
#5
Masumeh Faramarzi, Zahra Goharfar, Reza Pourabbas, Atabak Kashefimehr, Adileh Shirmohammadi
[This corrects the article on p. 181 in vol. 41, PMID: 26339576.].
December 2016: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/28050977/influence-of-age-on-factors-associated-with-peri-implant-bone-loss-after-prosthetic-rehabilitation-over-osseointegrated-implants
#6
Rejane El Pedro, João P De Carli, Maria Ss Linden, Igor Fp Lima, Luiz R Paranhos, Max D Costa, Ângelo Jg Bós
INTRODUCTION: To verify the influence of age on factors associated with peri-implant bone loss after prosthetic rehabilitation over osseointegrated implants. MATERIALS AND METHODS: This is an analytical, observational, and longitudinal study with initial 23 participants. Patients presenting with osseointegrated implants with their respective prostheses installed were included, and they could be carriers of chronic and degenerative diseases, such as diabetes, osteoporosis, hypothyroidism, cardiovascular disease (CVD), and systemic arterial hypertension...
January 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28050314/biocompatibility-study-of-lithium-disilicate-and-zirconium-oxide-ceramics-for-esthetic-dental-abutments
#7
Céline Brunot-Gohin, Jean-Luc Duval, Sandra Verbeke, Kayla Belanger, Isabelle Pezron, Gérard Kugel, Dominique Laurent-Maquin, Sophie Gangloff, Christophe Egles
PURPOSE: The increasing demand for esthetically pleasing results has contributed to the use of ceramics for dental implant abutments. The aim of this study was to compare the biological response of epithelial tissue cultivated on lithium disilicate (LS2) and zirconium oxide (ZrO2) ceramics. Understanding the relevant physicochemical and mechanical properties of these ceramics will help identify the optimal material for facilitating gingival wound closure. METHODS: Both biomaterials were prepared with 2 different surface treatments: raw and polished...
December 2016: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/28048963/effects-of-condensation-on-peri-implant-bone-density-and-remodeling
#8
L Wang, Y Wu, K C Perez, S Hyman, J B Brunski, U Tulu, C Bao, B Salmon, J A Helms
Bone condensation is thought to densify interfacial bone and thus improve implant primary stability, but scant data substantiate either claim. We developed a murine oral implant model to test these hypotheses. Osteotomies were created in healed maxillary extraction sites 1) by drilling or 2) by drilling followed by stepwise condensation with tapered osteotomes. Condensation increased interfacial bone density, as measured by a significant change in bone volume/total volume and trabecular spacing, but it simultaneously damaged the bone...
December 1, 2016: Journal of Dental Research
https://www.readbyqxmd.com/read/28048947/effect-of-implant-position-and-span-length-on-stresses-around-implants-assisting-claspless-distal-extension-partial-overdentures-an-invitro-study
#9
Moustafa Abdou Elsyad, Ahmed Kabeel, Nesreen Elmekawy
The aim of this invitro study was to evaluate the effect of implant position and edentulous span length on stresses around implants assisting claspless distal extension partial overdentures.Four bilateral mandibular distal extension acrylic models were constructed. Two implants were inserted in the distal extension ridges parallel to each other and perpendicular to the ridges. Based on the implant position, models were categorized into two groups: Group I, mesial implants position and Group II, distal implant position...
January 3, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28043375/comparative-dynamics-of-5-methylcytosine-reprogramming-and-tet-family-expression-during-preimplantation-mammalian-development-in-mouse-and-sheep
#10
F Jafarpour, S M Hosseini, S Ostadhosseini, H Abbasi, A Dalman, M H Nasr-Esfahani
Despite previous assumption that paternal active DNA demethylation is an evolutionary conserved phenomenon in mammals, emerging studies in other species, particularly sheep, do not support this issue. Recently, ten eleven translocation (TET) enzymes have been suggested as intermediates in genome-wide DNA demethylation through the iterative conversion of five methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC)/5-formylcytosine/5-carboxylcytosine (5caC) derivatives. This study investigated whether TET enzymes and 5mC derivatives are also involved in dynamic reprogramming of early sheep embryos derived by fertilization...
February 2017: Theriogenology
https://www.readbyqxmd.com/read/28042445/guided-bone-regeneration-via-a-preformed-titanium-foil-clinical-histological-and-histomorphometric-outcome-of-a-case-series
#11
M Andreasi Bassi, C Andrisani, S Lico, Z Ormanier, L Ottria, M Gargari
PURPOSE: The aim of this paper was to evaluate the histological and histomorphometric outcome of Preformed Titanium Foil (PTF) to perform Guided Bone Regeneration (GBR) in posterior mandibular atrophies. MATERIALS AND METHODS: 10 subjects (1 male; 9 females; mean age 58±11.37 years), with distal mandibular atrophies were selected to perform GBR by means of PTF, using a moldable allograft paste as graft material. The devices, made of a 0,2 mm thick pure titanium foil, were pre-shaped using stereolithographic models obtained from CT-scan of the patients' recipient site...
October 2016: Oral & Implantology
https://www.readbyqxmd.com/read/28042438/the-treatment-of-peri-implant-diseases-a-new-approach-using-hybenx-%C3%A2-as-a-decontaminant-for-implant-surface-and-oral-tissues
#12
M A Lopez, M Andreasi Bassi, L Confalone, F Silvestre, C Arcuri
PURPOSE: The aim of the present study is to demonstrate the efficacy of HyBeNX® to decontaminate the implant surface, both in the case mucositis and severe peri-implantitis and to allow future bone regeneration. MATERIALS AND METHODS: We describe three case reports of peri-implantitis successfully treated with HyBeNX®. In our study, we have used microbiological tests to demonstrate the efficacy of HyBeNX® in decreasing bacterial load. RESULTS: The microbiological results of the clinical cases described show that there was a reduction in the total bacterial count after treatment...
July 2016: Oral & Implantology
https://www.readbyqxmd.com/read/28040078/clinical-results-of-surgical-treatment-for-femoral-neck-fractures-with-the-targon-%C3%A2-fn
#13
Naohide Takigawa, Kenji Yasui, Hisako Eshiro, Hiromitsu Moriuchi, Muneki Abe, Seiya Tsujinaka, Mitsuo Kinoshita
84 cases (male 15 cases, female 69 cases) of intracapsular femoral neck fractures treated with the Targon(®) FN (TFN) were available for review. Mean patient age was 74.0 years (range 36-100 years). 55 fractures were undisplaced whereas 29 were displaced. Mean follow-up term was 16.4 months. We surveyed patient mobility before injury and after operation as well as postoperative complications. On a four-stage mobility scale we found 3/55 patients with undisplaced fractures loosing mobility by more than one grade (5...
December 2016: Injury
https://www.readbyqxmd.com/read/28039545/effects-of-enamel-matrix-derivative-on-non-surgical-management-of-peri-implant-mucositis-a-double-blind-randomized-clinical-trial
#14
Atabak Kashefimehr, Reza Pourabbas, Masumeh Faramarzi, Ali Zarandi, Abouzar Moradi, Howard C Tenenbaum, Amir Azarpazhooh
BACKGROUND: Peri-implant diseases have been recognized as being among the ever-increasing complications related to dental implants. The aim of this study was to evaluate the adjunctive use of enamel matrix derivative (EMD) to mechanical debridement (MD) in patients with these conditions in terms of clinical parameters and cytokine levels of peri-implant crevicular fluid (PICF). METHODS: In the present double-blind clinical trial, 46 patients with peri-implant mucositis (PM) were randomly divided into control and test groups...
December 30, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28035706/bioactive-glasses-as-delivery-systems-for-antimicrobial-agents
#15
REVIEW
Josefina Rivadeneira, Alejandro Gorustovich
Most biomaterial-associated infections are caused by opportunistic pathogens and bacteria that are regularly found within the microflora of the implant site. In addition, a biomaterial implant or device remains at risk of infection by hematogenous spread of bacteria disseminated from infections elsewhere in the body or from infected peri-implant tissue in revision surgery. The resulting infections are frequently accompanied by patient morbidity and discomfort and can lead to surgical replacement of the implant after lengthy, unsuccessful attempts to mitigate infections with antibiotic treatments...
December 30, 2016: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28033066/clinical-immune-and-microbiome-traits-of-gingivitis-and-peri-implant-mucositis
#16
G P Schincaglia, B Y Hong, A Rosania, J Barasz, A Thompson, T Sobue, F Panagakos, J A Burleson, A Dongari-Bagtzoglou, P I Diaz
Tissues surrounding dental implants and teeth develop clinical inflammation in response to microbial stimuli. However, the literature suggests that differences exist in the microbial insult and inflammatory responses leading to gingivitis and peri-implant mucositis. In this pilot study, the authors use for the first time a systems biology approach to comprehensively evaluate clinical parameters, selected inflammatory markers, and the microbiome of subject-matched tooth and implant sites during native inflammation and in response to experimental plaque accumulation...
January 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28032908/adjunctive-efficacy-of-probiotics-in-the-treatment-of-experimental-peri-implant-mucositis-with-mechanical-and-photodynamic-therapy-a-randomized-cross-over-clinical-trial
#17
Claudio Mongardini, Andrea Pilloni, Roberto Farina, Gianluca Di Tanna, Blerina Zeza
AIM: to evaluate the adjunctive clinical efficacy of probiotics in the treatment of peri-implant mucositis (p-iM) with professionally administered plaque removal (PAPR) and photodynamic therapy (PDT). MATERIALS AND METHODS: Following p-iM induction, patients underwent PAPR+PDT and were randomly assigned to receive the professional and home-based administration of probiotics (Lactobacillus plantarum and Lactobacillus brevis) (test treatment) or placebo preparation (control treatment) according to a cross-over design...
December 29, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28027610/effects-of-low-intensity-pulsed-ultrasound-on-implant-osseointegration-in-ovariectomized-rats
#18
Hongbo Zhou, Yongfu Hou, Zhimin Zhu, Weixiong Xiao, Qian Xu, Lei Li, Xin Li, Wenchuan Chen
OBJECTIVES: To investigate the effect of low-intensity pulsed ultrasound (US) on peri-implant bone healing and osseointegration under osteoporotic conditions. METHODS: Seventy-two 12-week-old female Sprague Dawley rats received bilateral ovariectomies. Twelve weeks later, titanium implants were bilaterally placed in the proximal tibial metaphysis. The right tibia was exposed to low-intensity pulsed US (40 mW/cm(2) , spatial and temporal average) for 20 min/d starting the 2nd day after implantation, and the left tibia served as a control without stimulation...
April 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28018568/the-prognosis-of-splinted-restoration-of-the-most-distal-implants-in-the-posterior-region
#19
Jong-Bin Lee, Man-Yong Kim, Chang-Sung Kim, Young-Taek Kim
PURPOSE: The aim of this study was to compare the efficacies of two-implant splinting (2-IS) and single-implant restoration (1-IR) in the first and second molar regions over a mean functional loading period (FLP) of 40 months, and to propose the appropriate clinical considerations for the splinting technique. MATERIALS AND METHODS: The following clinical factors were examined in the 1-IR and 2-IS groups based on the total hospital records of the patients: sex, mean age, implant location, FLP, bone grafting, clinical crown-implant ratio, crown height space, and horizontal distance...
December 2016: Journal of Advanced Prosthodontics
https://www.readbyqxmd.com/read/28013438/outcomes-of-implant-therapy-in-patients-with-a-history-of-aggressive-periodontitis-a-systematic-review-and-meta-analysis
#20
REVIEW
Charis Theodoridis, Andreas Grigoriadis, Georgios Menexes, Ioannis Vouros
OBJECTIVE: To investigate the outcomes of implant therapy in partially dentate patients treated for aggressive periodontitis (GAgP) in comparison to periodontally healthy (HP) and patients treated for chronic periodontitis (CP) utilizing radiographic and clinical parameters. MATERIAL AND METHODS: An electronic search of databases, supplemented by hand searching, was conducted to identify relevant clinical studies. Sequential screenings at the title, abstract and full-text levels were performed independently and in duplicate...
December 24, 2016: Clinical Oral Investigations
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