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Peri-implantitis

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https://www.readbyqxmd.com/read/28227792/an-innovative-therapy-for-peri-implantitis-based-on-radio-frequency-electric-current-numerical-simulation-results-and-clinical-evidence
#1
G Cosoli, L Scalise, G Tricarico, E P Tomasini, G Cerri, G Cosoli, L Scalise, G Tricarico, E P Tomasini, G Cerri, G Cosoli, E P Tomasini, G Cerri, G Tricarico, L Scalise
Peri-implantitis is a severe inflammatory pathology that affects soit and hard tissues surrounding dental implants. Nowadays, only prevention is effective to contrast peri-implantitis, but, in recent years, there is the clinical evidence of the efficiency of a therapy based on the application of radio frequency electric current, reporting that 81% of the cases (66 implants, 46 patients) were successfully treated. The aim of this paper is to present the therapy mechanism, exploring the distribution of the electric currents in normal and pathologic tissues...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224680/aberrant-expressions-of-endometrial-id3-and-ctla-4-are-associated-with-unexplained-repeated-implantation-failure-and-recurrent-miscarriage
#2
Jin-Li Ding, Liang-Hui Diao, Tai-Lang Yin, Chun-Yu Huang, Biao Yin, Cong Chen, Yi Zhang, Jie Li, Yan-Xiang Cheng, Yong Zeng, Jing Yang
Inhibitor of DNA-binding protein 3 (Id3) is required for tumor angiogenesis and regulatory T-cell generation. However, the involvement of Id3 in unexplained repeated implantation failure (RIF) and recurrent miscarriage (RM) remains poorly understood. Immunohistochemistry was used to identify Id3, CD34, CTLA-4, and FOXP3 in the endometrium taken from the women with RIF (n=16), RM (n=16) and matched controls (n=8). The images were acquired and analyzed by the Vectra(®) automated quantitative pathology imaging system...
February 21, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/28223139/the-role-of-il-1-gene-polymorphisms-il1a-il1b-and-il1rn-as-a-risk-factor-in-unsuccessful-implants-retaining-overdentures
#3
Margarida Sampaio Fernandes, Paula Vaz, Ana Cristina Braga, João Carlos Sampaio Fernandes, Maria Helena Figueiral
PURPOSE: Implant-supported overdentures are an alternative predictable rehabilitation method that has a high impact on improving the patient's quality of life. However, some biological complications may interfere with the maintenance and survival of these overdenture implants. The goal of this article was to assess the factors that affect peri-implant success, through a hypothetical prediction model for biological complications of implant overdentures. METHODS: A retrospective observational, prevalence study was conducted in 58 edentulous Caucasian patients rehabilitated with implant overdentures...
February 17, 2017: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/28218864/surgical-treatment-of-severe-peri-implantitis-using-a-round-titanium-brush-for-implant-surface-decontamination-a-case-report-with-clinical-re-entry
#4
Yinzhe An, Jae-Hong Lee, Young-Ku Heo, Jung-Seok Lee, Ui-Won Jung, Seong-Ho Choi
The most common cause of peri-implantitis is the accumulation of plaque and the formation of a biofilm on the implant surface. Terminating the development of the disease requires the biofilm to be removed from the implant surface. This paper describes two cases of severe peri-implantitis lesions treated through surgical approaches. Complete mechanical debridement with a round titanium brush was mainly performed to detoxify and modify the affected implant surface. A regenerative approach was then performed. In both cases, the surgical procedure was effective in arresting the peri-implantitis, and clinical re-entry revealed uneventful healing of the existing bone defect...
February 20, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28218496/functional-analysis-of-bioactivated-surfaces
#5
Selgai Haidari, Marko Boskov, Ulrike Schillinger, Klaus-Dietrich Wolff, Christian Plank, Andreas Kolk
Common scaffold surfaces, such as titanium, can have side effects, e.g., infections, cytotoxicity, impaired osseointegration or low regeneration rates for bone tissue. These effects lead to poor implant integration or even implant loss. Therefore, bioactive implants are promising instruments in tissue regeneration. Osteoinductive elements, such as growth factors and anti-infectives, support wound healing and bone growth and thereby enable faster osseointegration, even in elderly patients. In this study, titanium surfaces were coated with a poly-(D,L-lactide) (PDLLA) layer containing different concentrations of copolymer-protected gene vectors (COPROGs) to locally provide bone morphogenetic protein-2 (BMP-2) or activated anti-infective agents, such as chlorhexidine gluconate, triclosan and metronidazole, to prevent peri-implantitis...
February 20, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28213949/peri-implant-bone-remodeling-at-the-interface-of-three-different-implant-types-a-histomorphometric-study-in-mini-pigs
#6
Wenjuan Zhou, Sonja Kuderer, Zhonghao Liu, Christian Ulm, Xiaohui Rausch-Fan, Stefan Tangl
OBJECTIVES: The aim of this study was to perform a histomorphometric evaluation of the healing characteristics and jawbone remodeling processes in the peri-implant bone tissue of three commonly used implant surfaces, during the early weeks of osseointegration. MATERIAL AND METHODS: Dental implants with three different surfaces (anodically modified, hydroxyapatite (HA)-coated and machined) were inserted into the mandibular side-tooth region of twelve adult mini-pigs...
February 18, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28212453/bone-morphogenetic-protein-2-hybridized-with-nano-anchored-oligonucleotides-on-titanium-implants-enhances-osteogenic-differentiation-in-vivo
#7
Florian Böhrnsen, Jennifer Rublack, Nelia Aeckerle, Anne Foerster, Bernd Schwenzer, Judith Reichert, Dieter Scharnweber, Henning Schliephake
PURPOSE: Previous in vitro studies have shown that DNA oligonucleotides (ODN) can be successfully used as anchor strands for the binding and retarded release of biologically active recombinant human bone morphogenetic protein 2 (rhBMP-2). The aim of the present study was to test the hypothesis that rhBMP-2 bound to the surface of titanium implants through hybridization with nano-anchored ODN strands is biologically active and can enhance the induction of osteogenic markers in peri-implant bone in vivo...
February 17, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28212129/endoscopic-removal-of-a-dental-implant-from-maxillary-sinus
#8
Serkan Dundar, Turgut Karlidag, Erol Keles
The displacement of a dental implant into the maxillary sinus during surgery or after a period of use is a complication defined in the dental implant clinical practice. This complication arises primarily from inadequate bone height and peri-implant infection. Specifically, foreign objects in the maxillary sinus can cause sinusitis via impaired mucociliary flow and foreign body reactions, so they must be removed. Caldwell-Luc, transnasal, and intraoral endoscopic sinus surgeries have all been used to remove such foreign bodies and lesions from maxillary sinuses...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28211778/letter-to-the-editor-re-prevalence-etiology-and-treatment-of-peri-implant-mucositis-and-peri-implantitis-a-survey-of-periodontists-in-the-united-states
#9
https://www.readbyqxmd.com/read/28208793/chitosan-recombinamer-layer-by-layer-coatings-for-multifunctional-implants
#10
Jeevan Prasaad Govindharajulu, Xi Chen, Yuping Li, Jose Carlos Rodriguez-Cabello, Mrinal Battacharya, Conrado Aparicio
The main clinical problems for dental implants are (1) formation of biofilm around the implant-a condition known as peri-implantitis and (2) inadequate bone formation around the implant-lack of osseointegration. Therefore, developing an implant to overcome these problems is of significant interest to the dental community. Chitosan has been reported to have good biocompatibility and anti-bacterial activity. An osseo-inductive recombinant elastin-like biopolymer (P-HAP), that contains a peptide derived from the protein statherin, has been reported to induce biomineralization and osteoblast differentiation...
February 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28208056/oral-rehabilitation-of-a-patient-with-ectodermal-dysplasia-treated-with-fresh-frozen-bone-allografts-and-computer-guided-implant-placement-a-clinical-case-report
#11
Carlo Maiorana, Pier Paolo Poli, Carlo Poggio, Paola Barbieri, Mario Beretta
Ectodermal dysplasia (ED) is an inherited disorder characterized by abnormality of ectodermally derived structures. A recurrent oral finding is oligodontia, which in turn leads to a severely hypotrophic alveolar process with typical knife-edge morphology and adverse ridge contours. This unfavorable anatomy can seriously hamper proper implant placement. Fresh-frozen bone (FFB) allografts recently have been proposed to augment the residual bone volume for implant placement purposes; however, scientific evidence concerning the use of FFB to treat ED patients is absent...
January 20, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28203002/-role-of-different-scale-structures-of-titanium-implant-in-the-biological-behaviors-of-human-umbilical-vein-endothelial-cells
#12
N W Liang, L Shi, Y Huang, X L Deng
OBJECTIVE: To study the role of different scale structure of Ti implants on the biological behaviors of human umbilical vein endothelial cell (HUVECs) and to reveal the role of material surface topographical features on peri-implant angiogenesis. METHODS: Titanium (Ti) discs with different surface structures (Ti discs with smooth surface, Ti discs with nano scale structure, Ti discs with micro scale structure and Ti discs with micro/nano scale structure, named as SM-Ti, Nano-Ti, Micro-Ti and Micro/Nano-Ti, respectively) were prepared and their surface topographical features were confirmed via scanning electron microscopy (SEM) observation...
February 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28198975/short-term-sodium-alendronate-administration-improves-the-peri-implant-bone-quality-in-osteoporotic-animals
#13
Danila de Oliveira, Jaqueline Suemi Hassumi, Pedro Henrique da Silva Gomes-Ferreira, Tárik Ocon Braga Polo, Gabriel Ramalho Ferreira, Leonardo Perez Faverani, Roberta Okamoto
Objective: The aim of this study was to evaluate the bone repair process at the bone/implant interface of osteoporotic rats treated with sodium alendronate through the analysis of microtomography, real time polymerase chain reactions and immunohistochemistry (RUNX2 protein, bone sialoprotein (BSP), alkaline phosphatase, osteopontin and osteocalcin). Material and Methods: A total of 42 rats were used and divided in to the following experimental groups: CTL: control group (rats submitted to fictitious surgery and fed with a balanced diet), OST: osteoporosis group (rats submitted to a bilateral ovariectomy and fed with a low calcium diet) and ALE: alendronate group (rats submitted to a bilateral ovariectomy, fed with a low calcium diet and treated with sodium alendronate)...
January 2017: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28197990/a-chlorhexidine-releasing-epoxy-based-coating-on-titanium-implants-prevents-staphylococcus-aureus-experimental-biomaterial-associated-infection
#14
M Riool, A J Dirks, V Jaspers, L de Boer, T J Loontjens, C M van der Loos, S Florquin, I Apachitei, L N Rijk, H A Keul, S A Zaat
Prevention of biomaterial-associated infections (BAI) remains a challenging problem, in particular due to the increased risk of resistance development with the current antibiotic-based strategies. Metallic orthopaedic devices, such as non-cemented implants, are often inserted under high mechanical stress. These non-cemented implants cannot be protected by e.g. antibioticreleasing bone cement or other antimicrobial approaches, such as the use of bioactive glass. Therefore, in order to avoid abrasion during implantation procedures, we developed an antimicrobial coating with great mechanical stability for orthopaedic implants, to prevent Staphylococcus aureus BAI...
February 14, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28196278/carbon-fiber-vs-metal-framework-in-full-arch-immediate-loading-rehabilitations-of-the-maxilla-a-cohort-clinical-study
#15
Francesco Pera, Paolo Pesce, Francesco Solimano, Tiziano Tealdo, Paolo Pera, Maria Menini
BACKGROUND: Frameworks made of carbon fiber reinforced composites (CFRC) seem to be a viable alternative to traditional metal frameworks in implant prosthodontics. CFRC provide stiffness, rigidity and optimal biocompatibility. OBJECTIVE: The aim of the present prospective study was to compare carbon fiber frameworks versus metal frameworks used to rigidly splint implants in full-arch immediate loading rehabilitations. METHODS: 42 patients (test group) were rehabilitated with full-arch immediate loading rehabilitations of the upper jaw (total: 170 implants) following the Columbus Bridge Protocol with 4 to 6 implants with distal tilted implants...
February 14, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28196158/hybrid-implants-in-healthy-and-periodontally-compromised-patients-a-preliminary-clinical-and-radiographic-study
#16
Sergio Spinato, Fabio Bernardello, Paolo Sassatelli, Davide Zaffe
This preliminary clinical and radiographic study examined the survival of, the marginal bone loss (MBL) around, and the influence of prosthetic abutment height (AH) on MBL around hybrid implants placed in two groups of partially edentulous patients: healthy (HPs) and periodontally compromised (PCPs) patients. A total of 93 patients requiring single or multiunit implant restoration, in the mandible or maxilla, were treated while undergoing cement-retained prosthetic restoration. A total of 54 implants (35 in the maxilla and 19 in the mandible) were placed in 45 HPs, and 56 implants (31 in the maxilla and 25 in the mandible) in 48 PCPs...
March 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28196155/subperiosteal-minimally-invasive-aesthetic-ridge-augmentation-technique-smart-a-new-standard-for-bone-reconstruction-of-the-jaws
#17
Ernesto A Lee
Traditional guided bone regeneration techniques include flap mobilization and placement of a bone graft, often with the use of space-maintaining devices and cell-occlusive membranes. This approach is associated with frequent complications that negatively affect the outcome of the augmentation and the peri-implant soft tissue esthetics. Although current tunneling techniques have focused on periodontal soft tissue applications, earlier publications described their use for horizontal augmentation of mandibular posterior edentulous ridges in full-denture patients...
March 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28196152/human-histologic-evidence-of-reosseointegration-around-an-implant-affected-with-peri-implantitis-following-decontamination-with-sterile-saline-and-antiseptics-a-case-history-report
#18
Paul Fletcher, Daniel Deluiz, Eduardo Mb Tinoco, John L Ricci, Dennis P Tarnow, Justine Monnerat Tinoco
The treatment of peri-implant disease is one of the most controversial topics in implant dentistry. The multifactorial etiology and the myriad proposed techniques for managing the problem make successful decontamination of an implant surface affected by peri-implantitis one of the more unpredictable challenges dental practitioners have to face. This article presents the first known published case report demonstrating human histologic evidence of reosseointegration using a plastic curette for mechanical debridement and dilute sodium hypochlorite, hydrogen peroxide, and sterile saline for chemical detoxification...
February 14, 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28188903/microbiome-of-dental-implants-and-its-clinical-aspect
#19
REVIEW
Reghunathan S Preethanath, Nadia W AlNahas, Sahar M Bin Huraib, Hana O Al-Balbeesi, Naif Khalid Almalik, M H N Dalati, Darshan Devang Divakar
Although dental implants are most common prosthetic treatment used to replace missing tooth, it gained considerable importance over a decade owing to the availability of advanced imagery techniques that can help in achieving a greater success rate and much better osseointegration. However, the chances that the implanted tooth can be rejected due to inflammation caused by oral microflora still persist. This review gives the viewers an overall idea of the dental implants, role of advanced imaging in implantation and instances of peri-implantitis that occur after implantation process...
February 8, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28185382/autogenous-bone-block-grafting-provides-facial-implant-tissue-stability-long-term
#20
Fernando Verdugo, Agurne Uribarri, Antonio D'Addona
BACKGROUND: Mucosal recession (MR) and bone loss can compromise anterior implant esthetics. PURPOSE: To evaluate tissue stability and clinical outcomes of anterior implants augmented with autogenous block transplants long-term. MATERIALS AND METHODS: This prospective cross-sectional clinical study analyzed facial tissue recession of anterior implants augmented with autogenous bone blocks and compared them to adjacent teeth in forty patients 52 months post-augmentation...
February 10, 2017: Clinical Implant Dentistry and related Research
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