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Chronic pain and depression

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https://www.readbyqxmd.com/read/28108322/effect-of-zbd-2-on-chronic-pain-depressive-like-behaviors-and-recovery-of-motor-function-following-spinal-cord-injury-in-mice
#1
Xiao-Ming Li, Jia Meng, Lin Tao Li, Ting Guo, Liu-Kun Yang, Qi-Xin Shi, Xu-Bo Li, Yong Chen, Qi Yang, Jian-Ning Zhao
In addition to debilitating sensory and motor deficits, patients with spinal cord injury (SCI) may experience chronic hyperpathic pain (SCI-pain). Recent studies have revealed that translocator protein (TSPO) is involved in repairing neural cells as well as reducing anxiety and depression. However, the role of TSPO in SCI-pain and pain-induced depression remains unknown. The present study aimed to determine the effects of a new TSPO ligand, ZBD-2, on SCI-pain and consequent pain-induced depressive-like behaviors in mice...
January 17, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28107900/quality-of-sleep-in-renal-transplant-recipients-and-patients-on-hemodialysis
#2
Paraskevi G Liaveri, Dimitris Dikeos, Ioannis Ilias, Eirini P Lygkoni, Ioannis N Boletis, Chryssanthi Skalioti, Thomas Paparrigopoulos
BACKGROUND: Sleep disorders are very common in patients with chronic kidney disease and they may not always subside after kidney transplantation. AIM AND METHODS: The aim of this cross-sectional study was to evaluate the self-reported quality of sleep, insomnia problems in particular, and examine the factors that disturb sleep of kidney transplant recipients (KTx: n=152) in comparison to age- and sex-matched patients on dialysis (HD: n=67) and participants with normal renal function (NOR: n=49), through the administration of the Athens Insomnia Scale (AIS) at least six months after transplantation...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107898/the-experience-of-pain-severity-and-pain-interference-in-vulvodynia-patients-the-role-of-cognitive-behavioural-factors-psychological-distress-and-fatigue
#3
Claudia Chisari, Joseph Chilcot
OBJECTIVE: Vulvodynia is a chronic pain condition characterised by severe pain affecting the vulva. Biopsychosocial models have revealed the importance of illness perceptions, cognitive-behavioural variables and psychological distress in explaining the experience of pain and disability across several conditions. These factors have never been collectively examined in vulvodynia. We predicted that distress, fatigue, illness perceptions, and cognitive-behavioural factors would be associated with pain severity and interference among women with vulvodynia...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107599/the-prevalence-and-impact-of-chronic-neuropathic-pain-on-daily-and-social-life-a-nationwide-study-in-a-japanese-population
#4
S Inoue, T Taguchi, T Yamashita, M Nakamura, T Ushida
BACKGROUND: This study marks the first epidemiological evaluation of the prevalence and burden of chronic neuropathic pain (NeP) in an Asian population. The objective of this nationwide cross-sectional study was to identify the characteristics of individuals with NeP, detect the NeP features that affect their quality of life (QOL), and demonstrate the negative effects of NeP on social and daily living as well as comorbidities including depression, anxiety and sleep disorders. METHODS: We mailed a cross-sectional, population-based epidemiological survey to a random nationwide sample of 10,000 Japanese adults over 20 years old...
January 20, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28106666/a-tailored-guided-internet-based-cognitive-behavioral-intervention-for-patients-with-rheumatoid-arthritis-as-an-adjunct-to-standard-rheumatological-care-results-of-a-randomized-controlled-trial
#5
M Ferwerda, S van Beugen, H van Middendorp, S Spillekom-van Koulil, A R T Donders, H Visser, E Taal, M C W Creemers, P C L M van Riel, A W M Evers
For patients with chronic pain conditions such as rheumatoid arthritis (RA), who experience elevated levels of distress, tailored guided internet-based cognitive behavioral treatment may be effective in improving psychological and physical functioning, and reducing impact the impact of RA on daily life. A multicenter randomized controlled trial was conducted for RA patients with elevated levels of distress asassessed by a disease-specific measure. The control group (n=71) received standard care and the intervention group (n= 62) additionally received an internet-based tailored cognitive-behavioral intervention...
January 12, 2017: Pain
https://www.readbyqxmd.com/read/28104985/high-risk-of-temporomandibular-disorder-in-irritable-bowel-syndrome-is-there-a-correlation-with-greater-illness-severity
#6
Serena Gallotta, Vincenzo Bruno, Santo Catapano, Nicola Mobilio, Carolina Ciacci, Paola Iovino
AIM: To investigate the prevalence and the risk of temporomandibular disorders (TMDs) in patients with irritable bowel syndrome (IBS) (including each subtype: constipation, diarrhoea, and mixed) compared to the general population. METHODS: Between January 2014 and December 2015 we enrolled consecutively adult patients diagnosed with IBS at the outpatient clinic of the University of Salerno and healthy controls (HC) without IBS. At enrollment, we analyzed all patients for the presence of TMDs according to the Research Diagnostic Criteria for TMD...
January 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28101558/do-pain-characteristics-guide-selection-for-multimodal-pain-rehabilitation
#7
Paul Enthoven, Peter Molander, Birgitta Öberg, Britt-Marie Stålnacke, Gunilla Stenberg, Björn Gerdle
OBJECTIVE: To determine whether self-reported pain measures are associated with selection for multimodal or multidisciplinary rehabilitation (MMR) and whether this selection is influenced by sex. DESIGN: Cross-sectional cohort study. SUBJECTS: A total of 1,226 women and 464 men with chronic pain conditions from 2 university hospitals. METHODS: Drawing from the Swedish Quality Registry for Pain Rehabilitation (SQRP), data on pain, psychological symptoms, function, health, and activity/participation were collected...
January 18, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28100560/prevalence-impact-and-cost-of-multimorbidity-in-a-cohort-of-people-with-chronic-pain-in-ireland-a-study-protocol
#8
Brian W Slattery, Laura O'Connor, Stephanie Haugh, Christopher P Dwyer, Siobhan O'Higgins, Line Caes, Jonathan Egan, Brian E McGuire
INTRODUCTION: Multimorbidity (MM) refers to the coexistence of two or more chronic conditions within one person, where no one condition is considered primary. As populations age and healthcare provision improves, MM is becoming increasingly common and poses a challenge to the single morbidity approach to illness management, usually adopted by healthcare systems. Indeed, recent research has shown that 66.2% of the people in primary care in Ireland are living with MM. Healthcare usage and cost is significantly associated with MM, and additional chronic conditions lead to exponential increases in service usage and financial costs, and decreases in physical and mental well-being...
January 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28100238/chronic-physical-conditions-multimorbidity-and-physical-activity-across-46-low-and-middle-income-countries
#9
Davy Vancampfort, Ai Koyanagi, Philip B Ward, Simon Rosenbaum, Felipe B Schuch, James Mugisha, Justin Richards, Joseph Firth, Brendon Stubbs
BACKGROUND: There are no nationally representative population-based studies investigating the relationship between physical activity, chronic conditions and multimorbidity (i.e., two or more chronic conditions) in low- and middle-income countries (LMICs), and studies on a multi-national level are lacking. This is an important research gap, given the rapid increase in the prevalence of chronic diseases associated with lifestyle changes in these countries. This cross-sectional study aimed to assess the association between chronic conditions, multimorbidity and low physical activity (PA) among community-dwelling adults in 46 LMICs, and explore the mediators of these relationships...
January 18, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28099559/pain-induced-depression-is-related-to-overestimation-of-sleep-quality-in-a-very-elderly-population-with-pain
#10
Ricardo Humberto Felix, Carla Bezerra Lopes Almeida, Renata Carvalho Cremaschi, Fernando Morgadinho Coelho, Fânia Cristina Santos
Objective: To study the quality of sleep in very elderly people with chronic pain. Methods: We investigated 51 very elderly people without dementia and with chronic pain according to the Geriatric Pain Measure. Katz and Lawton questionnaires were used to evaluate functionality. The Geriatric Depression Scale and Geriatric Psychosocial Assessment of Pain-induced Depression were also used. Self-perceptions of sleep and quality of sleep were checked using the Pittsburgh Sleep Quality Index...
January 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28092651/long-lasting-antinociceptive-effects-of-green-light-in-acute-and-chronic-pain-in-rats
#11
Mohab M Ibrahim, Amol Patwardhan, Kerry B Gilbraith, Aubin Moutal, Xiaofang Yang, Lindsey A Chew, Tally Largent-Milnes, T Philip Malan, Todd W Vanderah, Frank Porreca, Rajesh Khanna
Treatments for chronic pain are inadequate, and new options are needed. Nonpharmaceutical approaches are especially attractive with many potential advantages including safety. Light therapy has been suggested to be beneficial in certain medical conditions such as depression, but this approach remains to be explored for modulation of pain. We investigated the effects of light-emitting diodes (LEDs), in the visible spectrum, on acute sensory thresholds in naive rats as well as in experimental neuropathic pain...
February 2017: Pain
https://www.readbyqxmd.com/read/28092649/new-onset-depression-following-stable-slow-and-rapid-rate-of-prescription-opioid-dose-escalation
#12
Joanne Salas, Jeffrey F Scherrer, Frank David Schneider, Mark D Sullivan, Kathleen K Bucholz, Thomas Burroughs, Laurel A Copeland, Brian K Ahmedani, Patrick J Lustman
Recent studies suggest that longer durations of opioid use, independent of maximum morphine equivalent dose (MED) achieved, is associated with increased risk of new-onset depression (NOD). Conversely, other studies, not accounting for duration, found that higher MED increased probability of depressive symptoms. To determine whether rate of MED increase is associated with NOD, a retrospective cohort analysis of Veterans Health Administration data (2000-2012) was conducted. Eligible patients were new, chronic (>90 days) opioid users, aged 18 to 80, and without depression diagnoses for 2 years before start of follow-up (n = 7051)...
February 2017: Pain
https://www.readbyqxmd.com/read/28092647/dietary-intake-mediates-the-relationship-of-body-fat-to-pain
#13
Charles F Emery, KayLoni L Olson, Andrew Bodine, Victoria Lee, Diane L Habash
Prior studies have documented an association of obesity with chronic pain, but the mechanism explaining the association remains unknown. This study evaluated the degree to which dietary intake of foods with anti-inflammatory effects mediates the relationship of body fat to body pain. Ninety-eight community-residing healthy adults (60% women; mean age = 43.2 ± 15.3 years; range: 20-78 years) participated in a home-based study of home environment, food-related behaviors, health, and adiposity. During a 3-hour home visit evaluation, 3 measures of body fat were collected, including height and weight for calculation of body mass index (BMI)...
February 2017: Pain
https://www.readbyqxmd.com/read/28092293/the-association-between-symptomatic-and-diagnostic-depression-and-pain-among-the-elderly-population-in-south-korea
#14
Wanhyung Lee, Kwanyoung Hong, Sung-Shil Lim, Dong Hyun Kim, Jin-Ha Yoon
The exact nature of pain (amount or severity) associated with in depression in the elderly population has not been studied extensively yet. We investigated the association between the characteristics of pain and both symptomatic and diagnostic depression using data from the 2012 Korean Longitudinal Study of Aging (2164 men, 2066 women). Symptomatic depression was identified a score of 12 or higher on the 10-item Center for Epidemiologic Studies-Depression Scale. Odds ratios with a 95% confidence interval was calculated for depression using multiple logistic regression models after adjusting for age, sex, socioeconomic status, health behavioral factors, and chronic diseases...
January 14, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28091795/mood-spectrum-disorders-and-perception-of-pain
#15
Antonella Ciaramella
: Evaluation of pain perception in chronic pain patients with a concomitant mood-spectrum disorder. DESIGN: The observational retrospective study is based on patient data collected in psychosomatic consultations held at the Gift Institute for Integrative Medicine in Pisa, Italy, from 2002 to 2014. Evoked pain stimulus threshold and tolerance were evaluated using the cold pressor test. Clinical pain intensity and Sensorial, Affective, and Evaluative dimensions were assessed using the Italian Pain Questionnaire, and Anxiety and Depressive symptoms using the Hospital Anxiety Depression Scale...
January 14, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28087891/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#16
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
January 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28077026/a-case-control-study-of-risk-factors-of-chronic-venous-ulceration-in-patients-with-varicose-veins
#17
Gohar Abelyan, Lusine Abrahamyan, Gayane Yenokyan
Background/objectives Venous ulcers carry psychological and high financial burden for patients, causing depression, pain, and limitation of mobility. The study aimed to identify factors associated with an increased risk of venous ulceration in patients with varicose veins in Armenia. Methods A case-control study design was utilized enrolling 80 patients in each group, who underwent varicose treatment surgery in two specialized surgical centers in Armenia during 2013-2014 years. Cases were patients with varicose veins and venous leg ulcers...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28076926/yoga-treatment-for-chronic-non-specific-low-back-pain
#18
REVIEW
L Susan Wieland, Nicole Skoetz, Karen Pilkington, Ramaprabhu Vempati, Christopher R D'Adamo, Brian M Berman
BACKGROUND: Non-specific low back pain is a common, potentially disabling condition usually treated with self-care and non-prescription medication. For chronic low back pain, current guidelines state that exercise therapy may be beneficial. Yoga is a mind-body exercise sometimes used for non-specific low back pain. OBJECTIVES: To assess the effects of yoga for treating chronic non-specific low back pain, compared to no specific treatment, a minimal intervention (e...
January 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28076692/the-effects-of-ultrasound-guided-corticosteroid-injection-for-the-treatment-of-hemiplegic-shoulder-pain-on-depression-and-anxiety-in-patients-with-chronic-stroke
#19
Min Cheol Chang
PURPOSE: We attempted to investigate whether ultrasound (US)-guided intraarticular or subacromial bursa corticosteroid injections can potentially influence the severity of depression and anxiety in patients with chronic stroke with hemiplegic shoulder pain (HSP). METHODS: Thirty patients with chronic stroke with HSP received US-guided corticosteroid injections. Numeric rating scale (NRS) scores, passive shoulder range of motion (ROM), Beck Depression Inventory (BDI) scores, and Spielberger State-Trait Anxiety Inventory (STAI) scores were evaluated before the injection, and one and two months after the injection...
January 11, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28073085/effect-of-investigator-observation-on-gait-parameters-in-individuals-with-and-without-chronic-low-back-pain
#20
Joshua Vickers, Austin Reed, Robert Decker, Bryan P Conrad, Marissa Olegario-Nebel, Heather K Vincent
Despite the ubiquity of gait assessment in clinic and research, it is unclear how observation impacts gait, particularly in persons with chronic pain and psychological stress. We compared temporal spatial gait patterns in people with and without chronic low back pain (CLBP) when they were aware and unaware of being observed. This was a repeated-measures, deception study in 55 healthy persons (32.0±12.4 yr, 24.2±2.7kg/m(2)) and persons with CLBP (51.9±17.9 yr, 27.8±4.4kg/m(2)). Participants performed one condition in which they were unaware of observation (UNW), and three conditions under investigator observation: (1) aware of observation (AWA), (2) investigators watching cadence, (3) investigators watching step length...
January 3, 2017: Gait & Posture
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