keyword
MENU ▼
Read by QxMD icon Read
search

gastrointestinal pathophysiology

keyword
https://www.readbyqxmd.com/read/29684865/the-effect-of-fecal-microbiota-transplantation-on-psychiatric-symptoms-among-patients-with-irritable-bowel-syndrome-functional-diarrhea-and-functional-constipation-an-open-label-observational-study
#1
Shunya Kurokawa, Taishiro Kishimoto, Shinta Mizuno, Tatsuhiro Masaoka, Makoto Naganuma, Kuo-Ching Liang, Momoko Kitazawa, Moeko Nakashima, Chie Shindo, Wataru Suda, Masahira Hattori, Takanori Kanai, Masaru Mimura
BACKGROUNDS: The intestinal microbiota is considered as a potential common underpinning pathophysiology of Functional Gastrointestinal Disorders (FGIDs) and psychiatric disorders such as depression and anxiety. Fecal Microbiota Transplantation (FMT) has been reported to have therapeutic effects on diseases related to dysbiosis, but few studies have evaluated its effect on psychiatric symptoms. METHODS: We followed 17 patients with either Irritable Bowel Syndrome (IBS), Functional Diarrhea (FDr) or Functional Constipation (FC) who underwent FMT for the treatment of gastrointestinal symptoms and observation of psychiatric symptoms...
April 12, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29670566/non-motor-symptoms-of-parkinson-s-disease-and-their-impact-on-quality-of-life-in-a-cohort-of-moroccan-patients
#2
Houyam Tibar, Khalil El Bayad, Ahmed Bouhouche, El Hachmia Ait Ben Haddou, Ali Benomar, Mohamed Yahyaoui, Abdelhamid Benazzouz, Wafa Regragui
Background: Non-motor symptoms (NMSs) are a real burden in Parkinson's disease (PD). They may appear in early pre-symptomatic stage as well as throughout the disease course. However, their relationship with the deterioration of the patient's quality of life (QoL) is still under debate. This study aimed to investigate the prevalence of NMSs and their impact on the QoL in a cohort of Moroccan patients. Methods: We carried out a cross-transactional study, where a total of 117 patients were submitted to a structured clinical interview and examination investigating motor and NMSs based on common and conventional scales...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29650525/flushing-disorders-associated-with-gastrointestinal-symptoms-part-1-neuroendocrine-tumors-mast-cell-disorders-and-hyperbasophila
#3
REVIEW
Vaibhav Rastogi, Devina Singh, Joseph J Mazza, Dennis Yang, Dipendra Parajuli, Steven H Yale
Flushing is the subjective sensation of warmth accompanied by visible cutaneous erythema occurring throughout the body with a predilection for the face, neck, pinnae, and upper trunk where the skin is thinnest and cutaneous vessels are superficially located and in greatest numbers. Flushing can be present in either a wet or dry form depending upon whether neural-mediated mechanisms are involved. Activation of the sympathetic nervous system results in wet flushing, accompanied by diaphoresis, due to concomitant stimulation of eccrine sweat glands...
April 12, 2018: Clinical Medicine & Research
https://www.readbyqxmd.com/read/29626394/microbiome-and-health-ramifications-of-intelligent-deception
#4
George B Stefano, Rachel Fine, Richard M Kream
Ten thousand years ago, the foundation for agricultural development and animal domestication was laid. Neolithic founder crops were carbohydrate-laden cereal grasses that facilitated transformation of hunter-gather societies into ancient civilizations with realistic capabilities for population expansion. In the last 3-4 decades, however, debilitating medical consequences of a progressively narrowed high caloric diet incorporating processed carbohydrates, animal protein, saturated fat and cholesterol, are translated into a global epidemic of obesity linked to metabolic and endocrine disorders, which, in part, emerged from the enhancement of our longevity...
April 7, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29623262/choosing-an-animal-model-for-the-study-of-functional-dyspepsia
#5
REVIEW
Yang Ye, Xue-Rui Wang, Yang Zheng, Jing-Wen Yang, Na-Na Yang, Guang-Xia Shi, Cun-Zhi Liu
Functional dyspepsia (FD) is a common functional gastrointestinal disorder with pain or discomfort in the upper abdomen as the main characteristic. The prevalence of FD worldwide varies between 5% and 11%. This condition adversely affects attendance and productivity in the workplace. Emerging evidence is beginning to unravel the pathophysiologies of FD, and new data on treatment are helping to guide evidence-based practice. In order to better understand the pathophysiologies of FD and explore better treatment options, various kinds of animal models of FD have been developed...
2018: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29605974/what-is-the-future-of-impedance-planimetry-in-gastroenterology
#6
REVIEW
Hans Gregersen, Kar Man Lo
The gastrointestinal (GI) tract is efficient in transporting ingested material to the site of delivery in healthy subjects. A fine balance exists between peristaltic forces, the mixing and delivery of the contents, and sensory signaling. This fine balance is easily disturbed by diseases. It is mandatory to understand the pathophysiology to enhance our understanding of GI disorders. The inaccessibility and complex nervous innervation, geometry and mechanical function of the GI tract make mechanosensory evaluation difficult...
April 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29602672/serum-levels-of-mirna-in-patients-with-hepatitis-b-virus-associated-acute-on-chronic-liver-failure
#7
Ya Wen, Shi-Fang Peng, Lei Fu, Xiao-Yu Fu, Da-Xian Wu, Bing-Jie Liu, De-Ming Tan, Yi Ouyang
BACKGROUND: Hepatitis B virus (HBV)-associated acute-on-chronic liver failure (HBV-ACLF) is a life-threatening condition and its exact pathophysiology and progression remain unclear. The present study aimed to assess the role of serum miRNAs in the evaluation of HBV-ACLF and to develop a model to predict the outcomes for ACLF. METHODS: Serum was collected from 41 chronic hepatitis B and 55 HBV-ACLF patients in addition to 30 chronic asymptomatic HBV carriers as controls...
March 13, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/29601123/hydrogen-sulfide-in-physiology-and-pathogenesis-of-bacteria-and-viruses
#8
REVIEW
Virender Kumar Pal, Parijat Bandyopadhyay, Amit Singh
An increasing number of studies have established hydrogen sulfide (H2 S) gas as a major cytoprotectant and redox modulator. Following its discovery, H2 S has been found to have pleiotropic effects on physiology and human health. H2 S acts as a gasotransmitter and exerts its influence on gastrointestinal, neuronal, cardiovascular, respiratory, renal, and hepatic systems. Recent discoveries have clearly indicated the importance of H2 S in regulating vasorelaxation, angiogenesis, apoptosis, ageing, and metabolism...
March 30, 2018: IUBMB Life
https://www.readbyqxmd.com/read/29600197/-herpes-simplex-virus-type-1-infects-enteric-neurons-and-triggers-gut-dysfunction-via-macrophage-recruitment
#9
Paola Brun, Marsela Qesari, Peggy C Marconi, Andromachi Kotsafti, Andrea Porzionato, Veronica Macchi, Reto A Schwendener, Marco Scarpa, Maria C Giron, Giorgio Palù, Arianna Calistri, Ignazio Castagliuolo
Herpes Simplex Virus type 1 (HSV-1), a neurotropic pathogen widespread in human population, infects the enteric nervous system (ENS) in humans and rodents and causes intestinal neuromuscular dysfunction in rats. Although infiltration of inflammatory cells in the myenteric plexus and neurodegeneration of enteric nerves are common features of patients suffering from functional intestinal disorders, the proof of a pathogenic link with HSV-1 is still unsettled mainly because the underlying mechanisms are largely unknown...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29596124/diverticular-disease-traditional-and-evolving-paradigms
#10
Lenore Lamanna, Patricia E Moran
Diverticular disease includes diverticulosis, which are sac protrusions of the intestinal mucosa, and diverticulitis, inflammation of the diverticula. Diverticular disease is listed as one of the top 10 leading physician diagnoses for gastrointestinal disorders in outpatient clinic visits in the United States. There are several classifications of diverticular disease ranging from asymptomatic diverticulosis to diverticulitis with complications. Several theories are linked to the development of diverticula which includes the physiology of the colon itself, collagen cross-linking, and recently challenged, low-fiber intake...
March 2018: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
https://www.readbyqxmd.com/read/29582208/update-on-bile-acid-malabsorption-finally-ready-for-prime-time
#11
REVIEW
Priya Vijayvargiya, Michael Camilleri
PURPOSE OF REVIEW: To provide an update on the prevalence, pathophysiology, disease associations, and treatment options for bile acid malabsorption (BAM). RECENT FINDINGS: •Molecular mechanisms-BAs prevent water reabsorption and increase water secretion by intracellular mediators, increasing aquaporin channels and intracellular permeability. •Inflammatory bowel disease-new molecular mechanisms of BAM are identified in patients without ileal disease, including changes in expression of ileal BA transporter and nuclear receptors involved in BA homeostasis...
March 26, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29582184/small-bowel-amyloidosis
#12
REVIEW
Raghav Bansal, Umer Syed, Jacob Walfish, Joshua Aron, Aaron Walfish
PURPOSE OF REVIEW: The goal of this paper is to review the literature on small bowel amyloidosis. Our review focuses on the underlying etiology, histopathology, clinical features, endoscopic and radiologic findings, and the mainstay of management. RECENT FINDINGS: The latest research shows changing epidemiological trends of different types of amyloidosis. It also reveals a better understanding of its pathophysiology and shows improvement in treatment outcomes. Amyloidosis is a group of diseases of multiple etiologies and clinical presentations...
March 26, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29577471/focal-but-not-global-cerebral-ischaemia-causes-loss-of-myenteric-neurons-and-upregulation-of-vasoactive-intestinal-peptide-in-mouse-ileum
#13
Xiaowen Cheng, Martina Svensson, Yiyi Yang, Tomas Deierborg, Eva Ekblad, Ulrikke Voss
Reduced blood flow to the brain induces cerebral ischaemia, potentially causing central injury and peripheral complications including gastrointestinal (GI) dysfunction. The pathophysiology behind GI symptoms is suspected to be neuropathy in the enteric nervous system (ENS), which is essential in regulating GI function. This study investigates if enteric neuropathy occurs after cerebral ischaemia, by analysing neuronal survival and relative numbers of vasoactive intestinal peptide (VIP) and neuronal nitric oxide synthase (nNOS) expressing neurons in mouse ileum after three types of cerebral ischaemia...
March 25, 2018: International Journal of Experimental Pathology
https://www.readbyqxmd.com/read/29570713/maternal-fetal-and-perinatal-factors-associated-with-necrotizing-enterocolitis-in-sweden-a-national-case-control-study
#14
Margareta Ahle, Peder Drott, Anders Elfvin, Roland E Andersson
OBJECTIVE: To analyze associations of maternal, fetal, gestational, and perinatal factors with necrotizing enterocolitis in a matched case-control study based on routinely collected, nationwide register data. STUDY DESIGN: All infants born in 1987 through 2009 with a diagnosis of necrotizing enterocolitis in any of the Swedish national health care registers were identified. For each case up to 6 controls, matched for birth year and gestational age, were selected...
2018: PloS One
https://www.readbyqxmd.com/read/29566601/investigation-of-microbiota-alterations-and-intestinal-inflammation-post-spinal-cord-injury-in-rat-model
#15
Gregory O'Connor, Elisabeth Jeffrey, Derik Madorma, Alexander Marcillo, Maria T Abreu, Sapna K Deo, W Dalton Dietrich, Sylvia Daunert
Although there has been a significant amount of research focused on the pathophysiology of Spinal Cord Injury (SCI), there is limited information on the consequences of SCI on remote organs. SCI can produce significant effects on a variety of organ systems, including the gastrointestinal tract. Patients with SCI often suffer from severe, debilitating bowel dysfunction in addition to their physical disabilities, which is of major concern for these individuals due to the adverse impact on their quality of life...
March 23, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29559160/a-multivariate-approach-to-the-diagnosis-of-gastrointestinal-infection-in-ewes
#16
Josiel Borges Ferreira, Renato Diógenes Macedo Paiva, Ana Carla Diógenes Suassuna Bezerra, José Ernandes Rufino de Sousa, Débora Andréa Evangelista Façanha
Diagnosing the effects of helminth infections is an efficient way to manage the problem in ruminant production systems. Selection of animals in a flock that are infected with Haemonchus has traditionally involved differential packed cell volume measurements (PCV), and in recent years, the FAMACHA© system has been used. However, few small analytical changes have been made. The objective of this study was to examine the influence of different diagnoses linked to packed cell volume (PCV) and FAMACHA© system scores in native ewes, using a multivariate approach...
March 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29556858/cyclic-vomiting-syndrome-in-children
#17
REVIEW
Anne Donnet, Sylvain Redon
PURPOSE OF REVIEW: Cyclic vomiting syndrome (CVS) is a misrecognized and probably underdiagnosed episodic syndrome associated with migraine, occurring preferentially in childhood. Attacks are stereotyped for each individual, with predictable periodicity. This review summarizes recent clinical and paraclinical observations in this syndrome, and current approaches in explorations and therapeutics. RECENT FINDINGS: Clinical phenotype during prodromal, vomiting, and recovery phases contains visceral and neuropsychological symptoms, but also cranial and systemic symptoms...
March 19, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29549458/gastrointestinal-symptoms-in-postural-tachycardia-syndrome-a-systematic-review
#18
REVIEW
Shahram E Mehr, Adrian Barbul, Cyndya A Shibao
Gastrointestinal symptoms are among the most common complaints in patients with postural tachycardia syndrome (POTS). In some cases, they dominate the clinical presentation and cause substantial disabilities, including significant weight loss and malnutrition, that require the use of invasive treatment to support caloric intake. Multiple cross-sectional studies have reported a high prevalence of gastrointestinal symptoms in POTS patients with connective tissue diseases, such as Ehlers-Danlos, hypermobile type, and in patients with evidence of autonomic neuropathy...
March 16, 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29545633/chronic-nausea-and-vomiting-evaluation-and-treatment
#19
REVIEW
Brian E Lacy, Henry P Parkman, Michael Camilleri
Nausea is an uneasy feeling in the stomach while vomiting refers to the forceful expulsion of gastric contents. Chronic nausea and vomiting represent a diverse array of disorders defined by 4 weeks or more of symptoms. Chronic nausea and vomiting result from a variety of pathophysiological processes, involving gastrointestinal and non-gastrointestinal causes. The prevalence of chronic nausea and vomiting is unclear, although the epidemiology of specific conditions, such as gastroparesis and cyclic vomiting syndrome, is better understood...
March 15, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29543651/early-signs-of-colonic-inflammation-intestinal-dysfunction-and-olfactory-impairments-in-the-rotenone-induced-mouse-model-of-parkinson-s-disease
#20
Lívia H Morais, Daniela B Hara, Maíra A Bicca, Anicleto Poli, Reinaldo N Takahashi
The factors that trigger the pathophysiology of Parkinson's disease (PD) are unknown. However, it is suggested that environmental factors, such as exposure to pesticides, play an important role, in addition to genetic predisposition and aging. Early signs of PD can appear in the gastrointestinal (GI) tract and in the olfactory system, preceding the onset of motor impairments by many years. The present study assessed the effects of oral rotenone administration (30 mg/kg) in inducing GI and olfactory dysfunctions associated with PD in mice...
April 2018: Behavioural Pharmacology
keyword
keyword
80025
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"