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https://www.readbyqxmd.com/read/29323049/autologous-transplantation-with-fewer-fibers-repairs-large-peripheral-nerve-defects
#1
Jiu-Xu Deng, Dian-Yin Zhang, Ming Li, Jian Weng, Yu-Hui Kou, Pei-Xun Zhang, Na Han, Bo Chen, Xiao-Feng Yin, Bao-Guo Jiang
Peripheral nerve injury is a serious disease and its repair is challenging. A cable-style autologous graft is the gold standard for repairing long peripheral nerve defects; however, ensuring that the minimum number of transplanted nerve attains maximum therapeutic effect remains poorly understood. In this study, a rat model of common peroneal nerve defect was established by resecting a 10-mm long right common peroneal nerve. Rats receiving transplantation of the common peroneal nerve in situ were designated as the in situ graft group...
December 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/29318854/-effect-of-electroacupuncture-on-intracellular-calcium-ion-concentration-and-expression-of-calcium-calmodulin-dependent-protein-kinase-%C3%A2-in-lumbar-spinal-cord-in-rats-with-neuropathic-pain
#2
Xin-Tian Wu, Wei Liang, Li-Ping Yan, Ling-Ling Wang, Cheng Ma
OBJECTIVE: To observe the changes of intracellular calcium ([Ca2+]i) concentration and expression of calcium/calmodulin dependent protein kinaseⅡ (CaMKⅡ) in spinal dorsal horn neurons of spared nerve injury (SNI) rats, so as to explore its mechanisms underlying improvement of neuropathic pain. METHODS: One hundred and ten SD rats were randomly divided into 5 groups: sham control, model, EA, AP-5 and L-NAME groups. The sham group underwent only a simple separation of the sciatic nerve but without ligation and abscission...
December 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29315664/outcomes-following-surgery-for-peroneal-intraneural-ganglion-cysts
#3
Thomas J Wilson, Michelle L Mauermann, Michael G Rock, Robert J Spinner
Introduction The objective of this study was to answer the typical questions from patients regarding the likely neurologic outcome and likelihood of recurrence when discussing peroneal intraneural ganglion cysts preoperatively. Methods Retrospective analysis of all patients who underwent surgery for a peroneal intraneural ganglion cyst between January 1, 2000 and April 1, 2017 was performed. Postoperative neurologic outcomes and radiologic recurrences are reported. Results There were 65 patients. Average clinical follow-up was 14 months...
January 9, 2018: Muscle & Nerve
https://www.readbyqxmd.com/read/29315576/the-metaboreflex-does-not-contribute-to-the-increase-in-muscle-sympathetic-nerve-activity-to-contracting-muscle-during-static-exercise-in-humans
#4
Daniel Boulton, Chloe E Taylor, Simon Green, Vaughan G Macefield
Both central command and metaboreflex inputs from contracting muscles increase muscle sympathetic nerve activity (MSNA) to non-contracting muscle during sustained isometric exercise. We recently showed that MSNA to contracting muscle also increases in an intensity-dependent manner, but whether this can be sustained by the metaboreflex is unknown. MSNA was recorded from the left common peroneal nerve and spikes of MSNA extracted. Eleven subjects performed a series of four-minute dorsiflexions of the left ankle at 10% of maximum voluntary contraction under three conditions: without ischaemia, with 6 min of post-exercise ischaemia and with ischaemia during and after exercise; these were repeated in the right leg...
January 8, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29315156/bleeding-risk-of-variceal-band-ligation-in-extrahepatic-portal-vein-obstruction-is-not-increased-by-oral-anticoagulation
#5
Maeva Guillaume, Camille Christol, Aurélie Plessier, Michèle Corbic, Jean-Marie Péron, Agnès Sommet, Pierre-Emmanuel Rautou, Yann Consigny, Jean-Pierre Vinel, Charles-Dominique Valla, Christophe Bureau
BACKGROUND AND OBJECTIVES: Noncirrhotic nontumoral extrahepatic portal vein obstruction (EHPVO) is the second leading cause of portal hypertension (PHT) and is mainly related to prothrombotic disorders. Patients with EHPVO often require prolonged oral anticoagulation therapy (OAT) together with variceal band ligation (VBL) to prevent thrombosis recurrence and PHT-related bleeding, respectively. The benefit-risk balance of VBL in this context remains unknown. We aimed to assess upper gastrointestinal bleeding (UGB) risk and variceal eradication efficacy in EHPVO patients undergoing a VBL program without stopping OAT...
January 8, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29313555/correlation-of-values-for-indocyanine-green-angiography-in-the-arterographically-normal-lower-extremity
#6
Paul J Kim, Christopher E Attinger, Cameron M Akbari, Caitlin Ward
INTRODUCTION: Indocyanine green angiography (ICGA) is an assessment tool used to detect the degree of perfusion of tissue. This technology is being utilized in a variety of applications, including in the lower extremity. Principally, ICGA has been reported as a tool to determine pre-, intra-, or post-operative perfusion. The aim of this study is to determine objective values for ICGA in patients with arterographically normal lower extremities. MATERIALS AND METHODS: Prospectively, 20 patients were identified with no history of peripheral vascular disease who were scheduled to undergo distal subtraction angiography of the lower extremity...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29309980/irreversible-foot-drop-as-a-consequence-of-neglected-knee-pain-in-an-adolescent-with-a-peroneal-intraneural-ganglion-cyst
#7
Nese Keser, Pinar Akpinar, Merih Is, Ilknur Aktas
No abstract text is available yet for this article.
January 5, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29309458/peroneus-quartus-muscle
#8
Alexander Habashy, Brandon Cook, Gonzalo Sumarriva, Robert Treuting
The peroneus quartus (PQ) muscle is a rare but sometimes missed potential etiology of ankle pain and tendon subluxation. We report the case of a 16-year-old boy who presented with lateral right ankle pain and subluxation of peroneal tendons. He had a history of non-Hodgkin lymphoma and palpable distal fibular osteochondroma. Seven months after excision of the exostosis and repair of the peroneal tendon retinaculum, the pain recurred. Imaging showed a split peroneus brevis (PB) tendon. During surgery, a PQ muscle was found and excised, and the PB tendon was repaired...
November 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/29303887/correlation-between-postoperative-central-corneal-thickness-and-endothelial-damage-after-cataract-surgery-by-phacoemulsification
#9
Jean Marc Perone, Mathilde Boiche, Louis Lhuillier, Francis Ameloot, Shamour Premy, Anne-Laure Jeancolas, Christophe Goetz, Estelle Neiter
PURPOSE: To study the correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification. METHODS: Eighty-five eyes of 85 consecutive patients with mild cataract (up to C5, N4, and P5: per LOCS III classification) were included in a prospective study from September 2014 to November 2014. Eighty-five eyes were necessary to obtain a precision of 0.15 for computation of the Pearson correlation coefficient...
January 4, 2018: Cornea
https://www.readbyqxmd.com/read/29300269/reply
#10
Jean Marc Perone, Christophe Goetz, Louis Lhuillier
No abstract text is available yet for this article.
January 3, 2018: Cornea
https://www.readbyqxmd.com/read/29300266/visibility-and-depth-of-the-stromal-demarcation-line-after-corneal-collagen-cross-linking-using-anterior-segment-optical-coherence-tomography-comparison-between-isoosmolar-and-hypoosmolar-riboflavin
#11
Louis Lhuillier, Cedric Ghetemme, Mathilde Boiché, Rekia Yahia, Naila Houmad, Mohamed Zaidi, Christophe Goetz, Jean Marc Perone
PURPOSE: To evaluate and compare visibility and depth of the stromal demarcation line (DL) created after corneal collagen cross-linking (CXL) using anterior segment optical coherence tomography (AS-OCT) between 2 groups: CXL with isoosmolar and hypoosmolar riboflavin. METHODS: In this retrospective study performed at Metz-Thionville Regional Hospital, consecutive patients with progressive keratoconus underwent CXL using an accelerated protocol (10 min, 9 mW/cm ultraviolet-A)...
January 3, 2018: Cornea
https://www.readbyqxmd.com/read/29299392/rapid-neurophysiological-screening-for-sensory-ganglionopathy-a-novel-approach
#12
Panagiotis Zis, Marios Hadjivassiliou, Ptolemaios Georgios Sarrigiannis, Alexander St John Edward Barker, Dasappaiah Ganesh Rao
Background and Aim: Pure sensory neuropathies involving the dorsal root ganglia are commonly referred to as sensory ganglionopathies (SG). Causes of SG can be inherited (as seen in Friedreich's ataxia) or acquired (e.g. immune-mediated or paraneoplastic). Diagnostic criteria for confirming SG have been published and consist of a combination of clinical and neurophysiological parameters. The aim of our study was to develop a neurophysiological method for rapid screening for diagnosis of SG...
December 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29291403/electrical-stimulation-as-a-conditioning-strategy-for-promoting-and-accelerating-peripheral-nerve-regeneration
#13
J L B Senger, V M K Verge, H S J Macandili, J L Olson, K M Chan, C A Webber
The delivery of a nerve insult (a "conditioning lesion") prior to a subsequent test lesion increases the number of regenerating axons and accelerates the speed of regeneration from the test site. A major barrier to clinical translation is the lack of an ethically acceptable and clinically feasible method of conditioning that does not further damage the nerve. Conditioning electrical stimulation (CES), a non-injurious intervention, has previously been shown to improve neurite outgrowth in vitro. In this study, we examined whether CES upregulates regeneration-associated gene (RAG) expression and promotes nerve regeneration in vivo, similar to a traditional nerve crush conditioning lesion (CCL)...
December 29, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/29291298/neurofibroma-of-the-peroneal-nerve
#14
Clayton Haldeman, Amgad Hanna
Neurofibromas are benign tumors composed of different cell types from the peripheral nervous system. Neurofibromas infiltrate between nerve fascicles and do not have a discrete capsule. On MRI, they are T1 hypointense or isointense, T2 hyperintense, often with a "target sign," and contrast enhancing. The video shows gross-total resection of a peroneal nerve neurofibroma presenting as a painful mass in the popliteal fossa. Incisions across a skin crease can be either oblique or zigzag, but never perpendicular to it...
January 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29291297/surgical-repair-of-sciatic-nerve-traumatic-rupture-technical-considerations-and-approaches
#15
Hussam Abou-Al-Shaar, Nam Yoon, Mark A Mahan
Traumatic proximal sciatic nerve rupture poses surgical repair dilemmas. Disruption often causes a large nerve gap after proximal neuroma and distal scar removal. Also, autologous graft material to bridge the segmental defect may be insufficient, given the sciatic nerve diameter. The authors utilized knee flexion to allow single neurorrhaphy repair of a large sciatic nerve defect, bringing healthy proximal stump to healthy distal segment. To avoid aberrant regeneration, the authors split the sciatic nerve into common peroneal and tibial divisions...
January 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29291292/peroneal-nerve-decompression
#16
Mark Corriveau, Jacob D Lescher, Amgad S Hanna
Peroneal neuropathy is a common pathology encountered by neurosurgeons. Symptoms include pain, numbness, and foot drop. When secondary to compression of the nerve at the fibular head, peroneal (fibular) nerve release is a low-risk procedure that can provide excellent results with pain relief and return of function. In this video, the authors highlight key operative techniques to ensure adequate decompression of the nerve while protecting the 3 major branches, including the superficial peroneal nerve, deep peroneal nerve, and recurrent genicular (articular) branches...
January 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29288924/short-term-effects-of-electrical-nerve-stimulation-on-spinal-reciprocal-inhibition-depend-on-gait-phase-during-passive-stepping
#17
Hiroki Obata, Tetsuya Ogawa, Matija Milosevic, Noritaka Kawashima, Kimitaka Nakazawa
A combination of electrical nerve stimulation (ENS) and passive or active cyclic movements (i.e., pedaling and stepping) has been suggested to induce stronger short-term effects in spinal circuits as compared to either intervention alone. The purpose of the present study is to determine whether the effects of ENS during passive stepping are dependent on the timing of the stimulation during the stepping cycle. A total of 10 able-bodied participants were recruited for the study. Two interventions were assessed during passive ground stepping: (1) ENS of the common peroneal nerve (CPN) during the swing phase (ENSswing) and (2) stance phase (ENSstance)...
December 26, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29284194/chronic-calf-pain-caused-by-fibroma-induced-chronic-inflammation-around-the-tibial-and-peroneal-nerves-that-was-misdiagnosed-as-centralized-neuropathic-pain-a-case-report
#18
Park Jiyoung, Ok Seong-Ho, Han Jeong Yeol, Park Miyeong, Seo Eun Hui, Kim Yeon A
INTRODUCTION: The etiology of calf pain varies widely; therefore, it is difficult to diagnose and requires careful history taking and physical examination by primary care unit physicians. Because ultrasonography is easy to perform, cheap, and readily available with physicians during a routine consultation, it is the first choice of modality for the evaluation of calf pain. However, simple inflammation around the nerve should also be considered as a possible etiology. Here we describe a 35-year-old man with chronic pain in the right calf that was actually caused by fibroma-induced chronic inflammation around the tibial and peroneal nerves but misdiagnosed as centralized neuropathic pain...
December 28, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29276600/atraumatic-bilateral-rupture-of-the-peroneus-brevis-tendon-in-recreational-sport-a-case-report
#19
Patric Scheidegger, Lukas Weisskopf, Anja Hirschmüller
Issue: Lower extremity tendon injuries often occur in physically active individuals. Most ruptures not involving great force are diagnosed in patients presenting underlying tendon degenerations. This also applies to patients taking medications because of a disease. We have observed several cases of bilateral Achilles tendon ruptures in patients who have been taking cortisone for a long period. We treated a healthy colleague (neurologist) in our clinic who sustained ruptures of the Achilles tendon on the left side (2012) and the peroneus brevis tendon on left side (2015) and right side (2016) after minimal traumata...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29249632/perforator-flaps-from-the-lower-leg-for-intraoral-reconstruction-experience-of-131-flaps
#20
Klaus-Dietrich Wolff, Andrea Rau, Andreas Kolk
BACKGROUND: During the last decade, perforator flaps have become popular for defect cover in the head and neck because they increase the choice of reconstructive possibilities and can lead to minimal donor site morbidity. In particular, the lower leg is considered a suitable option, as it provides thin and pliable skin for intraoral lining. Having gained experience with 131 flaps raised from four different donor sites at the lower leg, the aim of this paper is to evaluate success rates and patient satisfaction, but also difficulties and pitfalls during flap transfer...
November 26, 2017: Journal of Cranio-maxillo-facial Surgery
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