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Philippe Mortelmans, Marie-Christine Herregods, Filip Rega, Philippe Timmermans
BACKGROUND: Development of carcinoid heart disease (CHD) is the major negative prognostic factor in patients with the carcinoid syndrome. The only effective treatment is valve replacement. However, the selection of candidates and determination of optimal timing remain unclear. Considerable variability in local screening and treatment strategies exist. METHODS: In this single-centre study, we retrospectively analysed the diagnostic process and outcome of all CHD patients who underwent valve surgery between 2000 and 2016...
June 18, 2018: Acta Cardiologica
Hui-Min Hu, Xiao-Lin Zhang, Wei-Ling Zhang, Dong-Sheng Huang, Zhong-Dong Du
Background: Cardiotoxicity is one of the most serious chronic complications of anthracyclines therapy. Assessment of the left ventricular ejection fraction (LVEF) fails to detect subtle cardiac dysfunction of left ventricular (LV). This study aimed to detect and evaluate new parameters of subclinical anthracyclines' cardiotoxicity in children with solid tumor. Methods: A detailed echocardiographic examination was performed in 36 children with hepatoblastoma or rhabdomyosarcoma after receiving anthracyclines' chemotherapy and 36 healthy controls from January 2015 to December 2016...
June 20, 2018: Chinese Medical Journal
Marco Guazzi
No abstract text is available yet for this article.
September 1, 2018: International Journal of Cardiology
Khodr Tello, Jens Axmann, Hossein A Ghofrani, Robert Naeije, Newroz Narcin, Andreas Rieth, Werner Seeger, Henning Gall, Manuel J Richter
BACKGROUND: The ratio of echocardiography-derived tricuspid annular plane systolic excursion (TAPSE) and pulmonary arterial systolic pressure (PASP) has recently been reported as an independent prognostic parameter in heart failure. The TAPSE/PASP ratio has not been evaluated in detail in patients with pulmonary arterial hypertension (PAH). METHODS: We analyzed TAPSE/PASP in 290 patients with PAH entered into the Giessen Pulmonary Hypertension Registry between November 2003 and July 2014...
September 1, 2018: International Journal of Cardiology
Henning Johann Steffen, Sebastian Kalverkamp, Rashad Zayat, Rüdiger Autschbach, Jan-Wilhelm Spillner, Andreas Hagendorff, Nima Hatam
PURPOSE: To assess whether thoracic non-cardiac surgery has an influence on right ventricular function (RVF) compared to known impaired postoperative RV function after cardiac surgery. METHODS: In all, 50 patients (mean age: 61 years), who underwent thoracic non-cardiac surgery were included and matched using propensity score to 50 patients, receiving coronary artery bypass graft surgery (CABG) (CABGmatched ). All patients had transthoracic echocardiography (TTE) including two-dimensional speckle tracking (2D-STE) and tissue Doppler imaging (TDI) pre- and 1 week postoperatively...
June 7, 2018: Annals of Thoracic and Cardiovascular Surgery
Jie Sheng Foo, Maksym Lazu, Si Ying Pang, Phong Teck Lee, Ju Le Tan
BACKGROUND: To determine differences in right heart remodeling for patients with ASD who underwent surgical compared to device closure. METHODS: Retrospective analysis of echo data of 121 adult patients with ASD from 2005 to 2015 performed prior to closure and within 6-8 weeks, 6 months, and 1 year post closure. RESULTS: 121 patients with median age of 39 were studied. Patients who underwent device closure were older (46 vs 37 years, P < 0...
June 4, 2018: Journal of Interventional Cardiology
Philipp Burghard, Fabian Plank, Christoph Beyer, Silvana Müller, Jakob Dörler, Marc-Michael Zaruba, Leo Pölzl, Gerhard Pölzl, Andrea Klauser, Stefan Rauch, Fabian Barbieri, Christian-Ekkehardt Langer, Wilfried Schgoer, Eric E Williamson, Gudrun Feuchtner
OBJECTIVES: To evaluate right ventricle (RV) function by coronary computed tomography angiography (CTA) using a novel automated three-dimensional (3D) RV volume segmentation tool in comparison with clinical reference modalities. METHODS: Twenty-six patients with severe end-stage heart failure [left ventricle (LV) ejection fraction (EF) <35%] referred to CTA were enrolled. A specific individually tailored biphasic contrast agent injection protocol was designed (80%/20% high/low flow) was designed...
June 4, 2018: European Radiology
Marco Zanobini, Claudia Loardi, Paolo Poggio, Gloria Tamborini, Fabrizio Veglia, Alessandro Di Minno, Veronika Myasoedova, Liborio Francesco Mammana, Raoul Biondi, Mauro Pepi, Francesco Alamanni, Matteo Saccocci
BACKGROUND: The reduction of RV function after cardiac surgery is a well-known phenomenon. It could persist up-to one year after the operation and often leads to an incomplete recovery at follow-up echocardiographic control. The aim of the present study is to analyze the impact of different modalities of pericardial incision (lateral versus anterior) and of myocardial protection protocols (Buckberg versus Custodiol) onto postoperative RV dynamic by relating two- and three-dimensional echocardiographic parameters in patients undergoing mitral valve repair through minimally invasive or traditional surgery approach...
June 5, 2018: Journal of Cardiothoracic Surgery
Jeremias Götschke, Pontus Mertsch, Nikolaus Kneidinger, Diego Kauffmann-Guerrero, Jürgen Behr, Rudolf Maria Huber, Frank Reichenberger, Katrin Milger
Chronic hypoxia causes pulmonary vascular remodeling resulting in persistently increased pulmonary arterial pressures (PAP) even after return to normoxia. Recently, interest in chronic intermittent hypobaric hypoxia (CIHH) was raised because it occurs in subjects working at high altitude (HA) but living in lowland. However, effects of daily CIHH on PAP are unknown. In this pilot study, we included 8 healthy subjects working at (2650 m) each workday for 8-9 h while living and sleeping at LA and 8 matched control subjects living and working at LA...
2018: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
Stephen J Huang, Marek Nalos, Louise Smith, Arvind Rajamani, Anthony S McLean
PURPOSE: Many echocardiographic indices (or methods) for assessing right ventricular (RV) function are available, but each has its strengths and limitations. In some cases, there might be discordance between the indices. We conducted a systematic review to audit the echocardiographic RV assessments in critical care research to see if a consistent pattern existed. We specifically looked into the kind and number of RV indices used, and how RV dysfunction was defined in each study. METHODS: Studies conducted in critical care settings and reported echocardiographic RV function indices from 1997 to 2017 were searched systematically from three databases...
May 22, 2018: Intensive Care Medicine
Francesco Ferrara, Luna Gargani, Saku Ruohonen, Olga Vriz, Marco Scalese, Valentina Russo, Alberto M Marra, Anna Agnese Stanziola, Antonio Cittadini, Antonello D'Andrea, Robert Naeije, Eduardo Bossone
BACKGROUND: Right atrial (RA) volume is an important parameter in the evaluation of patients with pulmonary hypertension. Aim of this study was to define reference ranges for RA volume by two-dimensional echocardiography (2DE) in healthy adults. METHODS: A total of 596 healthy subjects [mean age 45.7 ± 14.6 years, range 18-88 years; 60.1% women] underwent a transthoracic echocardiography. In addition, a meta-analysis was performed of published studies measuring RA volume in healthy subjects, using 2DE single plane area-length (A-L) and/or method of disks (MOD) at end-systole in apical four-chamber view...
May 14, 2018: Echocardiography
Simbo Chiadika, Mary Lim-Fung, Fiorella Llanos-Chea, Astrid Serauto Canache, Wei Yang, Christina Paruthi, Xu Zhang, David D McPherson, Modupe Idowu
BACKGROUND: Sickle cell disease (SCD) affects millions of people and causes chronic hemolytic anemia leading to vasculopathies such as pulmonary hypertension and abnormalities in cardiac function that increase complications and mortality. It is therefore crucial to identify cardiac abnormalities in SCD. We aimed to assess the prevalence of echocardiographic parameters in SCD to help identify cardiopulmonary risk. METHODS: Ninety-one patients (53% male), median age of 30, body surface area (BSA) of 1...
May 14, 2018: Echocardiography
Ilaria Spalla, Jessie Rosie Payne, Kieran Borgeat, Virginia Luis Fuentes, David John Connolly
INTRODUCTION: Hypertrophic cardiomyopathy (HCM) has a variable prognosis; left atrial size, presence of clinical signs and left ventricular systolic function have been shown to predict outcomes. Mitral annular plane systolic excursion (MAPSE) and tricuspid annular plane systolic excursion (TAPSE) assess longitudinal ventricular systolic function and are decreased in cats with HCM. The aim of the study was to ascertain whether MAPSE and TAPSE have prognostic value in HCM and if cats with pleural effusion have lower MAPSE and TAPSE than cats with pulmonary oedema...
May 10, 2018: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Arvind Sehgal, Stella M Gwini, Samuel Menahem, Beth J Allison, Suzanne L Miller, Graeme R Polglase
KEY POINTS: Approximately 5-10% pregnancies are affected by fetal growth restriction. Preterm infants affected by fetal growth restriction have a higher incidence of bronchopulmonary dysplasia. This study is the first to measure pulmonary artery thickness and stiffness. It highlights that impaired vasculogenesis may be a contributory factor in the higher incidence of bronchopulmonary dysplasia in preterm growth restricted infants. The study addresses the mechanistic link between fetal programming and vascular architecture and mechanics...
May 10, 2018: Journal of Physiology
David S Raymer, Jonathan D Moreno, Marc A Sintek, Michael E Nassif, Christopher T Sparrow, Luigi Adamo, Eric L Novak, Shane J LaRue, Justin M Vader
Right ventricular (RV) failure is difficult to predict and is a major determinant of poor outcomes after left ventricular assist device (LVAD) implantation. We evaluated the associations of the following variables with severe RV failure in LVAD patients: tricuspid annular plane systolic excursion (TAPSE), pulmonary artery pulsatility index (PAPi), simplified RV contraction pressure index (sRVCPI), and HeartMate Risk Score (HMRS). We performed a retrospective case-control study on 216 patients who underwent continuous-flow LVAD implantation between 2008 and 2014...
April 26, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
M Hünlich, E Lubos, B E Beuthner, M Puls, A Bleckmann, T Beißbarth, T Tichelbäcker, V Rudolph, S Baldus, U Schäfer, H Treede, R S Von Bardeleben, S Blankenberg, W Schillinger
Positive results of MitraClip in terms of improvement in clinical and left ventricular parameters have been described in detail. However, long-term effects on secondary pulmonary hypertension were not investigated in a larger patient cohort to date. 70 patients with severe mitral regurgitation, additional pulmonary hypertension, and right heart failure as a result of left heart disease were treated in the heart centers Hamburg and Göttingen. Immediately after successful MitraClip implantation, a reduction of the RVOT diameter from 3...
2018: BioMed Research International
L C Visser, D J Sintov, M S Oldach
INTRODUCTION: We sought to determine the feasibility, measurement variability, and within-day repeatability of tricuspid annular plane systolic excursion (TAPSE) measured by two-dimensional echocardiography (2D TAPSE), generate reference intervals for 2D TAPSE, assess agreement and correlation between 2D TAPSE and the conventional TAPSE measured by M-mode echocardiography (MM TAPSE), and to assess the ability of 2D TAPSE to track a drug-induced decrease in right ventricular (RV) function compared with MM TAPSE...
April 30, 2018: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Angel López-Candales, Antonio J Sotolongo-Fernandez, Francisco López Menéndez, Maria D Candales
In this retrospective study 420 echocardiograms from a single center were reviewed showing that TAPSE was acquired in 66% while TA TDI s' signals were recorded in 98% of all echocardiograms. Based on these results greater efforts are required to standardize acquisition and reporting of objective measurements of RV function.
March 2018: Indian Heart Journal
Yoshihiro Kamimura, Naoki Okumura, Shiro Adachi, Shigetake Shimokata, Fumitaka Tajima, Yoshihisa Nakano, Akihiro Hirashiki, Toyoaki Murohara, Takahisa Kondo
Right ventricular (RV) function is associated with prognosis in chronic thromboembolic pulmonary hypertension (CTEPH). This study aimed to establish an RV dysfunction score using RV echocardiographic parameters to clarify the clinical characteristics in patients with CTEPH and to compare RV dysfunction score with parameters such as World Health Organization (WHO) functional class, hemodynamics, exercise capacity, and plasma BNP level. We enrolled 35 inpatients with CTEPH (mean age, 62 ± 15 years, 15 males)...
April 27, 2018: Heart and Vessels
Michael Ch Seng, Xiayan Shen, Kangjie Wang, Daniel Tt Chong, Jiang Ming Fam, Nadira Hamid, Mohammed Rizwan Amanullah, Khung Keong Yeo, See Hooi Ewe, Terrance Sj Chua, Zee Pin Ding, Anders Sahlén
BACKGROUND: Cardiac size measurements require indexing to body size. Allometric indexing has been investigated in Caucasian populations but a range of different values for the so-called allometric power exponent ( b ) have been proposed, with uncertainty as to whether allometry offers clinical utility above body surface area (BSA)-based indexing. We derived optimal values for b in normal echocardiograms and validated them externally in cardiac patients. Methods and Results: Values for b were derived in healthy adult Chinese males (n=1,541), with optimal b for left ventricular mass (LVM) of 1...
April 25, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
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