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Patrick Collier, Bo Xu, Kenya Kusunose, Dermot Phelan, Andrew Grant, Paaladinesh Thavendiranathan, Brian P Griffin, Richard A Grimm, Thomas H Marwick, Zoran B Popović
Background: Assessment of right ventricular (RV) function plays an important role in patients with cardiopulmonary disease, and current guidelines recommend parameters including tricuspid annular plane systolic excursion (TAPSE) and right ventricular systolic excursion velocity (RVS') to assess RV longitudinal function. We assessed the hypothesis that the previously undescribed motion of RV longitudinal rotation (RVLR) is an independent predictor of both TAPSE and RVS'. Methods: We assessed a series of 100 consecutive patients with pulmonary hypertension (PH) undergoing echocardiography...
August 2018: Journal of Thoracic Disease
Tommaso Vezzosi, Oriol Domenech, Giulia Costa, Federica Marchesotti, Luigi Venco, Eric Zini, Maria Josefa Fernández Del Palacio, Rosalba Tognetti
BACKGROUND: Right ventricular (RV) enlargement and dysfunction are associated with prognosis in humans with pulmonary hypertension (PH). HYPOTHESIS/OBJECTIVES: To assess RV size and systolic function in dogs with PH and to determine if they are associated with disease severity and right-sided congestive heart failure (R-CHF). ANIMALS: 89 dogs with PH and 74 healthy dogs. METHODS: Prospective observational study. PH was classified according to the tricuspid regurgitation pressure gradient...
September 14, 2018: Journal of Veterinary Internal Medicine
Francois Potus, Charles Colin Thomas Hindmarch, Kimberly J Dunham-Snary, Jeff Stafford, Stephen L Archer
Right ventricular failure (RVF) remains the leading cause of death in pulmonary arterial hypertension (PAH). We investigated the transcriptomic signature of RVF in hemodynamically well-phenotyped monocrotaline (MCT)-treated, male, Sprague-Dawley rats with severe PAH and decompensated RVF (increased right ventricular (RV) end diastolic volume (EDV), decreased cardiac output (CO), tricuspid annular plane systolic excursion (TAPSE) and ventricular-arterial decoupling). RNA sequencing revealed 2547 differentially regulated transcripts in MCT-RVF RVs...
September 12, 2018: International Journal of Molecular Sciences
Selina Hein, Fabian Aus Dem Siepen, Ralf Bauer, Hugo A Katus, Arnt V Kristen
INTRODUCTION: Cardiopulmonary exercise testing (CPET) has repeatedly been reported to reliably predict adverse outcomes in different forms of heart failure. However, it has not been elucidated in detail in cardiac amyloidosis (CA). Therefore, we evaluated the predictive value of CPET parameters in patients with CA regarding disease severity and prediction of mortality. METHODS: Twenty-seven consecutive patients with CA were assessed noninvasively, including electrocardiography, echocardiography, CPET, and laboratory tests...
September 7, 2018: Amyloid: the International Journal of Experimental and Clinical Investigation
Matthias Schneider, Stefan Aschauer, Julia Mascherbauer, Hong Ran, Christina Binder, Irene Lang, Georg Goliasch, Thomas Binder
Echocardiographic evaluation of right ventricular (RV) function is a challenge due to the complex anatomy of the RV. Several transthoracic echocardiographic methods have been suggested for the quantification of RV function. However, many of the parameters are time consuming and need dedicated hardware and software. We suspected that the majority of the established markers are not used on a wide basis. In a multinational online survey, we evaluated the use of current clinical standards for the quantification of RV function in clinical practice...
September 6, 2018: International Journal of Cardiovascular Imaging
Viola William, Wael El Kilany
Background: The main focus of most of the studies in heart failure (HF) is the assessment of the left ventricular functions, while the right ventricle was much less studied. Much of this neglect is due to the complexity of anatomy and physiology of the right ventricle which are considered challenges during assessment of RV. Objective: [1] To review the alterations of right ventricular dimensions & function associated with chronic heart failure. [2] To predict the prevalence of right ventricular systolic dysfunction in patients with chronic heart failure, based on echocardiographic parameters...
September 2018: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
Ahmed Shawky Elserafy, Ahmed Nabil, Ali Ali Ramzy, Mohamed Abdelmenem
Background: Right ventricular involvement in ST segment elevation myocardial infarction (STEMI) entails an increased morbidity and mortality. However, very scarce data is present on its affection in the setting of non-ST segment elevation myocardial infarction (NSTEMI). Aim: To assess the affection of right ventricular function in patients presenting with NSTEMI undergoing an invasive procedure. Subjects and methods: One hundred and fifty patients admitted with a first NSTEMI and eligible for reperfusion therapy via invasive percutaneous coronary intervention...
September 2018: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
Shadi Lahham, John C Fox, Maxwell Thompson, Tanyaporn Nakornchai, Badriah Alruwaili, Ghadeer Doman, Shannon May Lee, Amal Shafi, Inna Shniter, Victoria Valdes, Lishi Zhang
INTRODUCTION: The imaging standard for evaluation of acute pulmonary embolism (PE) includes a computed tomography pulmonary angiogram. Ultrasonography has shown promise in obtaining the tricuspid annular plane systolic excursion (TAPSE) measurements, which may be of clinical importance in patients with acute PE. The objective of this study is to evaluate the diagnostic capability of TAPSE measurements for patients with suspicion for acute PE. METHODS: We prospectively enrolled patients who came to the emergency department with suspicion of acute PE...
September 4, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Jamie K Harrington, Lindsay R Freud, Kristal L Woldu, Anna Joong, Marc E Richmond
RV systolic function is important early after HT; however, it has not been critically assessed in children using quantitative measures. The aim of this study was to describe the most validated and commonly used quantitative echocardiographic measures of RV systolic function early after pediatric HT and to assess associations with qualitative function evaluation and clinical factors. RV systolic function was quantified on the first post-HT echocardiogram >24 hours after cardiopulmonary bypass using two-dimensional TAPSE, Tricuspid annular S', FAC, and MPI...
September 3, 2018: Pediatric Transplantation
Gabriel Altit, Shazia Bhombal, Valerie Y Chock, Theresa A Tacy
Right ventricular (RV) function as assessed by deformation has been evaluated prenatally and after palliation in hypoplastic left heart syndrome (HLHS). However, limited data exist about the immediate postnatal cardiac adaptation and RV function in HLHS. We compared echocardiographic measures of cardiac performance in HLHS versus controls in their first week of life. As a secondary objective, we evaluated if markers at the first echocardiogram were associated with mid- and long-term outcomes. Clinical and echocardiographic data of patients with HLHS between 2013 and 2016 were reviewed...
September 3, 2018: Pediatric Cardiology
Roberto Badagliacca, Stefano Ghio, Michele Correale, Roberto Poscia, Rita Camporotondo, Armando Ferraretti, Silvia Papa, Beatrice Pezzuto, Pasquale Petrone, Roberto Torre, Matteo Di Biase, Paola Novara, Stefania Guida, Carmine Dario Vizza
BACKGROUND: Mortality following an admission for acute decompensated heart failure (ADHF) is high and risk stratification in this context remains a challenge. The objective of the present study was to assess whether a simple echocardiographic assessment of pulmonary hypertension (PH) and/or of right ventricular (RV) dysfunction is associated with cardiovascular events in a 1-year follow-up after hospital discharge. METHODS AND RESULTS: The present prospective longitudinal study included 214 patients admitted to hospital with a cardiologist-adjudicated diagnosis of ADHF and a left ventricular ejection fraction (LVEF) at echocardiography < 40%...
November 15, 2018: International Journal of Cardiology
Jem D Lane, Sarah Whittaker-Axon, Richard J Schilling, Martin D Lowe
BACKGROUND: Implantable cardioverter-defibrillator (ICD) lead parameters may deteriorate due to right ventricular (RV) disease such as arrhythmogenic right ventricular cardiomyopathy (ARVC), with implications for safe delivery of therapies. We compared ICD and CRT-D (cardiac resynchronisation therapy-defibrillator) lead parameters in patients with ARVC and dilated cardiomyopathy (DCM). METHODS: RV lead sensing (R wave amplitude) and pacing (threshold and amplitude-pulse width product (APWP)), left ventricular (LV) pacing (APWP), and imaging parameter trends were assessed in 18 patients with ARVC and 18 with DCM...
August 23, 2018: Indian Pacing and Electrophysiology Journal
R Perveen, M H Hoque, K Ahmed, C M Ahmed, M A Jalil, T Parvin, D F Osmany, S Rashid, M B Rashid, S Nahar, S S Shakil
Diastolic dysfunction is a major predictor of mortality and morbidity in hypertensive patients. Not only LV, the RV is also expected to be affected in this overall procedure. To observe the Echocardiographic changes of diastolic function of the RV in systemic HTN and their relation with similar parameters of the LV was the objective. TDI was used in association with standard Doppler modality. In this cross-sectional study, 50 hypertensive subjects were studied who were devoid of any other conditions that may influence the diastolic function of the RV from 01 May 2012 to 31 October 2012 at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh...
July 2018: Mymensingh Medical Journal: MMJ
S M Cunningham, B D Aona, K Antoon, J E Rush, B A Barton
OBJECTIVES: To determine whether there are differences in measures of longitudinal right ventricular (RV) systolic function among Boxers with arrhythmogenic right ventricular cardiomyopathy (ARVC) compared with healthy control Boxer dogs. To explore relationships between markers of RV systolic function and age, body weight, gender, arrhythmia frequency, and markers of left ventricular (LV) systolic function in Boxer dogs. ANIMALS: The study included 50 client-owned Boxer dogs...
August 20, 2018: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Javad Shahabi, Reihaneh Zavar, Afshin Amirpour, Mohammad Bidmeshki, Melinaz Barati-Chermahini
BACKGROUND: Acute pulmonary thromboembolism (PTE) is a common disease with a high mortality rate, and a variable and nonspecific clinical presentation. To detect the nonspecific signs and symptoms associated with this condition, several right ventricular (RV) echocardiographic parameters have been proposed as practical marker. METHODS: This cross-sectional study was performed on 93 patients with PTE diagnosed by computed tomography (CT) angiography, and 57 patients with negative PTE based on CT angiography...
March 2018: ARYA Atherosclerosis
Wei Zhuang, Guili Lian, Bangbang Huang, Apang Du, Genfa Xiao, Jin Gong, Changsheng Xu, Huajun Wang, Liangdi Xie
Pulmonary arterial hypertension (PAH) in humans manifests as a chronic process. However, PAH induced by high-dose monocrotaline (MCT) in animals occurs as a subacute process. To establish a chronic PAH model, rats were randomly divided into three groups, control (ctrl), single injection (SI), and twice injection (TI) groups. Rats in the SI group received a single intraperitoneal injection of 40 mg/kg MCT on day 0. Rats in the TI group received twice injections of 20 mg/kg MCT on days 0 and 7. Survival percentage, characteristic changes of pulmonary arterial variables, and right ventricular features were evaluated...
August 12, 2018: Experimental Biology and Medicine
Ibrahim Sultan, Arturo Cardounel, Islam Abdelkarim, Arman Kilic, Andrew D Althouse, Michael S Sharbaugh, Aman Gupta, Jeff Xu, Miho Fukui, Marc A Simon, John T Schindler, Joon S Lee, Thomas G Gleason, João L Cavalcante
OBJECTIVES: To evaluate the prognostic value of the ratio between tricuspid annular plane systolic excursion (TAPSE)-pulmonary artery systolic pressure (PASP) as a determinant of right ventricular to pulmonary artery (RV-PA) coupling in patients undergoing transcatheter aortic valve replacement (TAVI). BACKGROUND: RV function and pulmonary hypertension (PH) are both prognostically important in patients receiving TAVI. RV-PA coupling has been shown to be prognostic important in patients with heart failure but not previously evaluated in TAVI patients...
August 9, 2018: Heart: Official Journal of the British Cardiac Society
Ágnes Nógrádi, Adél Porpáczy, Lili Porcsa, Tünde Minier, László Czirják, András Komócsi, Réka Faludi
Cardiac involvement in systemic sclerosis (SSc) implies a worse prognosis. Little is known about the right atrial (RA) mechanics in this disease, but recent data suggest that it correlates well with the functional capacity of the patients in conditions with known right heart involvement. Thus we aimed to investigate the abnormalities of the RA function as compared with healthy subjects and to assess the potential correlations between RA mechanics and the functional capacity in SSc patients using 2D speckle tracking technique...
July 4, 2018: American Journal of Cardiology
Hongmin Zhang, Xiaoting Wang, Xiukai Chen, Qing Zhang, Dawei Liu
BACKGROUND: The tricuspid annular plane systolic excursion (TAPSE) is commonly recommended for estimating the right ventricular systolic function. The central venous pressure (CVP), which is determined by venous return and right heart function, was found to be associated with right ventricular outflow fractional shortening. This study thus aimed to investigate the relationship between the TAPSE and CVP in mechanically ventilated critically ill patients. METHODS: This is a prospective observational study...
August 7, 2018: Cardiovascular Ultrasound
Jose-Luis Moya Mur, Ana García Martín, Alberto García Lledó, Carla Lázaro Rivera, Luis Miguel Rincón Díaz, Javier Miguelena Hycka, Ilaria Boretti, Camila Gimaraes, Eduardo Casas Rojo, Jose-Julio Jiménez Nacher, Covadonga Fernández-Golfín, Jorge Rodríguez-Roda Stuart, José Luis Zamorano
Cardiac surgery induces geometrical and functional changes, which are not clearly explained. OBJECTIVE: to investigate the physiopathology of the heart after cardiac surgery using advanced techniques of echocardiography. Thirty patients undergoing cardiac surgery had echocardiographic study prior and after surgery. Left and right ventricular (RV) longitudinal displacement and strain were studied with speckle-tracking. Using longitudinal displacement, we defined a static longitudinal reference-point (sLRP) to which the other segments moved during systole...
August 2, 2018: International Journal of Cardiovascular Imaging
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