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Kyoung Im Cho, Min Gu Chon
OBJECTIVE: Inhaled ilroprost can improve clinical status and symptoms in Eisenmenger syndrome (ES). Right ventricular (RV) function is important prognostic factor of pulmonary arterial hypertension. But there has been insufficient data in echocardiographic parameters related to RV function after long term iloprost therapy. So we evaluated effect of long term iloprost treatment on RV function and other parameters measured by echocardiography in this study. DESIGN AND METHOD: Eleven consecutive patients with ES associated with congenital heart disease underwent echocardiographic measurements at baseline and 48 weeks after iloprost therapy...
September 2016: Journal of Hypertension
Lorin Arie Schwartz, Zach Rozenbaum, Ehab Ghantous, Judith Kramarz, Simon Biner, Michael Ghermezi, Jason Shimiaie, Ariel Finkelstein, Shmuel Banai, Galit Aviram, Meirav Ingbir, Gad Keren, Yan Topilsky
BACKGROUND: Right ventricular (RV) dysfunction and tricuspid regurgitation (TR) may coexist with aortic stenosis. The aim of this study was to assess the association between RV dysfunction, TR, associated comorbidities, and outcomes following transcatheter aortic valve replacement (TAVR). METHODS: A retrospective analysis was conducted of baseline and 6-month clinical and echocardiographic parameters, including TR grade, RV size (grade, end-diastolic and end-systolic areas, annular diameter), and function (grade, tricuspid annular plane systolic excursion [TAPSE], fractional area change, Tei index), in 519 consecutive TAVR patients...
October 11, 2016: Journal of the American Society of Echocardiography
José L Díaz-Gómez, Andres Borja Alvarez, Jonathan J Danaraj, Michelle L Freeman, Augustine S Lee, Farouk Mookadam, Brian P Shapiro, Harish Ramakrishna
OBJECTIVES: The tricuspid annular plane systolic excursion (TAPSE) is a validated measure of right ventricular function; however, the apical echocardiographic window varies and has limitations in intensive care unit (ICU) patients receiving mechanical ventilation or those with underlying disease and air entrapment. We aimed to evaluate the subcostal echocardiographic assessment of tricuspid annular kick (SEATAK) as an alternative to TAPSE in critically ill patients. METHODS: To measure SEATAK, we obtained the subcostal inferior vena cava view and used M-mode to measure excursion of the tricuspid annulus (kick)...
October 14, 2016: Echocardiography
Basant M Elnady, Ayman Saeed Mohamed Abdelghafar, El Shazly Abdul Khalik, Mohammed Mesfer Algethami, A S Basiony, Mona Dhaif Allah Al-Otaibi, Maram Eidhah Al-Otaibi
OBJECTIVE: Systemic lupus erythematosus (SLE) can present limitations to exercise capacity and quality of life (QoL) because of various clinical conditions, such as pulmonary disease or heart disease. Tissue Doppler echocardiography (TDE) offers the promise of an objective measurement to quantify regional and global ventricular function through the assessment of myocardial velocity data. This study aimed to assess the intensity of left ventricular (LV) and right ventricular (RV) systolic and diastolic dysfunction in SLE patients by means of TDE and cardiopulmonary exercise (CPX) testing to determine their impact on QoL...
September 2016: Eur J Rheumatol
Elio Aloia, Matteo Cameli, Flavio D'Ascenzi, Carlotta Sciaccaluga, Sergio Mondillo
RV function is an important component of overall heart function with prognostic value in predicting symptomatic limitation and outcome in different cardiovascular pathologies. RV longitudinal contraction accounts for the majority of total RV function, up to 80%, as compared to transverse shortening. Calculation of RV volume and RV ejection fraction (RVEF) remains hampered by the complex RV geometry and we lack a good geometric model allowing the calculation of right ventricular ejection fraction; secondly, the large apical trabeculations of the right ventricle make the endocardial delineation more difficult to obtain than for the left ventricle...
October 5, 2016: International Journal of Cardiology
Michele D'Alto, Adriana Pavelescu, Paola Argiento, Emanuele Romeo, Anna Correra, Giovanni Maria Di Marco, Antonello D'Andrea, Berardo Sarubbi, Maria Giovanna Russo, Robert Naeije
BACKGROUND: Exercise-induced increase in pulmonary artery systolic pressure (PASP) as a possible measure of right ventricular (RV) contractile reserve has been shown to predict survival in severe pulmonary hypertension. However, RV contractile reserve can also be measured by changes in stroke volume (SV), tricuspid annular plane systolic excursion (TAPSE), or tricuspid annular systolic velocity (S'). The limits of normal values and the functional significance of these changes in healthy subjects are not well known...
October 2, 2016: Echocardiography
Marzanna Paczyńska, Piotr Sobieraj, Łukasz Burzyński, Maciej Kostrubiec, Małgorzata Wiśniewska, Piotr Bienias, Katarzyna Kurnicka, Barbara Lichodziejewska, Piotr Pruszczyk, Michał Ciurzyński
INTRODUCTION: Right ventricular dysfunction (RVD) is an indicator of poor prognosis in normotensive patients with acute pulmonary embolism (APE). The aim of this study was to compare right ventricular (RV)/left ventricular (LV) ratio measured by echocardiography and multidetector computed tomography (MDCT) with tricuspid annulus plane systolic excursion (TAPSE) as a prognostic factor of APE-related 30-day mortality. MATERIAL AND METHODS: We examined 76 patients with confirmed APE, hemodynamically stable at admission...
October 1, 2016: Archives of Medical Science: AMS
M Qasem, V Utomi, K George, J Somauroo, A Zaidi, L Forsythe, S Bhattacharrya, G Lloyd, B Rana, L Ring, S Robinson, R Senior, N Sheikh, M Sitali, J Sandoval, R Steeds, M Stout, J Willis, D Oxborough
INTRODUCTION: Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inherited pathology that can increase the risk of sudden death. Current Task Force Criteria for echocardiographic diagnosis do not include new, regional assessment tools which may be relevant in a phenotypically diverse disease. We adopted a systematic review and meta-analysis approach to highlight echocardiographic indices that differentiated ARVC patients and healthy controls. METHODS: Data was extracted and analysed from prospective trials that employed a case-control design meeting strict inclusion and exclusion as well as a-priori quality criteria...
September 29, 2016: Echo Research and Practice
Joseph A Sivak, Amresh Raina, Paul R Forfia
Total right heart function requires normal function of both the right ventricle and the right atrium. However, the degree to which right atrial (RA) function and right ventricular (RV) function each contribute to total right heart function has not been quantified. In this study, we aimed to quantify the contribution of RA function to total right heart function in a group of pulmonary arterial hypertension (PAH) patients compared to a cohort of normal controls without cardiovascular disease. The normal cohort comprised 35 subjects with normal clinical echocardiograms, while the PAH cohort included 37 patients, of whom 31 had echocardiograms before and after initiation of PAH-specific therapy...
September 2016: Pulmonary Circulation
Aroditis Konstantinos, Pikilidou Maria, Vourvouri Eleni, Hadjistavri Lina, Zebekakis Pantelis, Yovos John, Efthimiadis George, Karvounis Haralambos
Overproduction of thyroid hormones leads to structural as well as functional cardiac changes. Conventional echocardiography but also recently developed sophisticated two-dimensional echocardiography speckle (2D-STE) tracking allow elaborate evaluation of these changes. Our purpose was to investigate the effects of thyroid hormones overproduction on the heart in patients with Graves' disease and changes that occur after 6 months thyrostatic therapy. We conducted a prospective, case-control study of 6 months duration...
September 28, 2016: International Journal of Cardiovascular Imaging
Silvia Lai, Mauro Ciccariello, Mira Dimko, Alessandro Galani, Silvio Lucci, Rosario Cianci, Amalia Mariotti
: Bakground/Aims: Cardiovascular diseases represent the leading causes of morbidity and mortality in patients with cronich kidney disease (CKD). The pathogenesis includes a complex, bidirectional interaction between heart and kidney termed cardiorenal syndrome type 4. The aim of study was to evaluate the association between renal and cardiovascular ultrasonographic parameters and identify early markers of cardiovascular risk. METHODS: A total of 35 patients with CKD and 25 healthy controls, were enrolled and we have evaluated inflammatory indexes, mineral metabolism, renal function, renal and cardiovascular ultrasonographic parameters...
September 26, 2016: Kidney & Blood Pressure Research
Morteza Abdar Esfahani, Fariborz Mokarian, Mohammad Karimipanah
BACKGROUND: Anthracycline-induced cardiotoxicity can reach an irreversible phase; therefore great efforts are made to diagnose it early. As the right ventricle (RV) is smaller than the left, the right side of the heart is probably influenced by anthracycline to a greater extent and in a shorter time. The purpose of the present study was to investigate the early effects of chemotherapy on the right side of the heart. METHODS: This cross-sectional study was performed in Isfahan University hospitals from August 2014 to December 2015...
September 20, 2016: Postgraduate Medical Journal
Thomas M Gorter, Elke S Hoendermis, Dirk J van Veldhuisen, Adriaan A Voors, Carolyn S P Lam, Bastiaan Geelhoed, Tineke P Willems, Joost P van Melle
AIMS: Right ventricular (RV) dysfunction and pulmonary hypertension (PH) are increasingly recognized in heart failure with preserved ejection fraction (HFpEF). The prevalence and prognostic value of RV dysfunction in HFpEF have been widely but variably reported. We therefore conducted a systematic review and meta-analysis according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses. METHODS AND RESULTS: English literature until May 2016 was evaluated for prevalence of RV dysfunction [i...
September 20, 2016: European Journal of Heart Failure
Frank Lloyd Dini, Erberto Carluccio, Anca Simioniuc, Paolo Biagioli, Gianpaolo Reboldi, Gian Giacomo Galeotti, Claudia Raineri, Luna Gargani, Laura Scelsi, Giulia Elena Mandoli, Antonia Cannito, Andrea Rossi, Pier Luigi Temporelli, Stefano Ghio
AIMS: A compromised tricuspid annular plane systolic excursion (TAPSE) is associated with worse survival in patients with chronic heart failure with reduced ejection fraction (HFrEF). However, it is not known whether a reversible abnormal TAPSE at follow-up predicts survival. Our aim was to evaluate whether a reversible abnormal TAPSE is associated with a better survival in patients with chronic HFrEF. METHODS AND RESULTS: A complete echocardiography was performed in 706 patients with chronic HFrEF (LVEF ≤45%) at baseline and after 6 ± 3 months...
September 20, 2016: European Journal of Heart Failure
G Tedesco, L C Bussamra, L C Rolo, F S Barros, W P Martins, L Nardozza, A F Moron, E Araujo
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
Kyoung Im Cho, Min Gu Chon
OBJECTIVE: Inhaled ilroprost can improve clinical status and symptoms in Eisenmenger syndrome (ES). Right ventricular (RV) function is important prognostic factor of pulmonary arterial hypertension. But there has been insufficient data in echocardiographic parameters related to RV function after long term iloprost therapy. So we evaluated effect of long term iloprost treatment on RV function and other parameters measured by echocardiography in this study. DESIGN AND METHOD: Eleven consecutive patients with ES associated with congenital heart disease underwent echocardiographic measurements at baseline and 48 weeks after iloprost therapy...
September 2016: Journal of Hypertension
J Degenhardt, C Enzensberger, A Tenzer, A Kawecki, T Kohl, E Widriani, R Axt-Fliedner
: Purpose: To evaluate pre- and postprocedural myocardial function in fetuses with moderate to severe congenital diaphragmatic hernia (CDH) who underwent FETO to improve survival and to reduce morbidity and to compare these data with fetuses and CDH not undergoing FETO and normal controls. Materials and Methods: 8 fetuses with isolated left-sided CDH were included and underwent FETO at our center between 2012 and 2013. Prior to and after the operation, myocardial function was assessed by measuring the mitral annular plane systolic excursion (MAPSE), the tricuspid annular plane systolic excursion (TAPSE), Tei index, isovolumetric contraction time (ICT), ejection time (ET), isovolumetric relaxation time (IRT) for the left ventricle in PW Doppler ultrasound as well as ICT, ET, IRT and Tei index in pulsed wave tissue Doppler imaging (PW-TDI) for the left and right ventricle...
September 14, 2016: Ultraschall in der Medizin
Anders Christensson, Anders Grubb, John Molvin, Hannes Holm, Klas Gransbo, Gordana Tasevska-Dinevska, Erasmus Bachus, Amra Jujic, Martin Magnusson
The close relationship between heart and kidney diseases was studied with respect to the 'Shrunken pore syndrome' that is characterized by a difference in renal filtration between cystatin C and creatinine. Patients were retrieved from the HeARt and brain failure inVESTigation trail (HARVEST) which is an ongoing study undertaken in individuals hospitalized for the diagnosis of heart failure. Ninety-five of 116 patients who underwent transthoracic echocardiograms (TTE) were eligible for this study. We used four different formulas for estimated glomerular filtration rate (eGFR); CKD-EPIcreatinine, CKD-EPIcystatin C, LMrev and CAPA...
November 2016: Scandinavian Journal of Clinical and Laboratory Investigation
Steven M Kawut, Christine L Archer-Chicko, Angela DiMichele, Jason S Fritz, James R Klinger, Bonnie Ky, Harold I Palevsky, Amy J Palmisciano, Mamta Patel, Diane Pinder, Kathleen J Propert, K Akaya Smith, Frank Stanczyk, Russell Tracy, Anjali Vaidya, Mary E Whittenhall, Corey E Ventetuolo
RATIONALE: The aromatase inhibitor anastrozole blocks the conversion of androgens to estrogen and blunts pulmonary hypertension in animals, but its efficacy in treating patients with pulmonary arterial hypertension (PAH) is unknown. OBJECTIVES: We aimed to determine the safety and efficacy of anastrozole in PAH. METHODS: We performed a randomized, double-blind, placebo-controlled trial of anastrozole in patients with PAH receiving background therapy at two centers...
September 7, 2016: American Journal of Respiratory and Critical Care Medicine
Darrin J Wong, Unnati Sampat, Michael A Gibson, William R Auger, Michael M Madani, Lori B Daniels, Ajit B Raisinghani, Anthony N DeMaria, Daniel G Blanchard
BACKGROUND: Right ventricular function is impaired in chronic thromboembolic pulmonary hypertension (CTEPH). Tricuspid annular plane systolic excursion (TAPSE) and right ventricular fractional area change (RVFAC) have been shown to help assess right ventricular function in pulmonary hypertension. Our goal was to (1) assess TAPSE and RVFAC before and after PTE, and (2) assess correlation of these variables with right heart catheterization data and PVR. METHODS: We evaluated 67 consecutive patients with CTEPH for pulmonary thromboendarterectomy (PTE)...
September 7, 2016: Echocardiography
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