keyword
https://read.qxmd.com/read/38617690/artesunate-alleviates-kidney-fibrosis-in-type-1-diabetes-with-periodontitis-rats-via-promoting-autophagy-and-suppression-of-inflammation
#1
JOURNAL ARTICLE
Chen Liang, Licheng Ma, Yi Chen, Jiaquan Li, Binge Wang, Chubin Ma, Zhong Yuan, Xiaolin Nong
To explore the effect of periodontal disease on the progression of diabetic kidney disease (DKD), to observe the effects of artesunate (ART) intervention on periodontal and kidney tissues in type 1 diabetic rats with periodontitis, and to explore the possibility of ART for the treatment of DKD. Rat models of diabetes mellitus, periodontitis, and diabetes mellitus with periodontitis were established through streptozotocin (STZ) intraperitoneal injection, maxillary first molar ligation, and P. gingivalis ligation applied sequentially...
April 9, 2024: ACS Omega
https://read.qxmd.com/read/38612211/biomechanics-of-the-human-osteochondral-unit-a-systematic-review
#2
REVIEW
Matteo Berni, Gregorio Marchiori, Massimiliano Baleani, Gianluca Giavaresi, Nicola Francesco Lopomo
The damping system ensured by the osteochondral (OC) unit is essential to deploy the forces generated within load-bearing joints during locomotion, allowing furthermore low-friction sliding motion between bone segments. The OC unit is a multi-layer structure including articular cartilage, as well as subchondral and trabecular bone. The interplay between the OC tissues is essential in maintaining the joint functionality; altered loading patterns can trigger biological processes that could lead to degenerative joint diseases like osteoarthritis...
April 8, 2024: Materials
https://read.qxmd.com/read/38588680/b-mar-bidirectional-artifact-representations-learning-framework-for-metal-artifact-reduction-in-dental-cbct
#3
JOURNAL ARTICLE
Yuyan Song, Tianyi Yao, Shengwang Peng, Manman Zhu, Ming Qiang Meng, Jianhua Ma, Dong Zeng, Jing Huang, Yongbo Wang, Zhaoying Bian
Metal artifacts in computed tomography (CT) images hinder diagnosis and treatment significantly. Specifically, dental cone-beam computed tomography (Dental CBCT) images are seriously contaminated by metal artifacts due to the widespread use of low tube voltages and the presence of various high-attenuation materials in dental structures. Existing supervised metal artifact reduction (MAR) methods mainly learn the mapping of artifact-affected images to clean images, while ignoring the modeling of the metal artifact generation process...
April 8, 2024: Physics in Medicine and Biology
https://read.qxmd.com/read/38534502/state-of-the-art-in-the-diagnosis-and-assessment-of-oral-malignant-and-potentially-malignant-disorders-present-insights-and-future-outlook-an-overview
#4
REVIEW
Dardo Menditti, Mario Santagata, David Guida, Roberta Magliulo, Giovanni Maria D'Antonio, Samuel Staglianò, Ciro Emiliano Boschetti
Oral Potentially Malignant Disorder (OPMD) is a significant concern for clinicians due to the risk of malignant transformation. Oral Squamous Cell Carcinoma (OSCC) is a common type of cancer with a low survival rate, causing over 200,000 new cases globally each year. Despite advancements in diagnosis and treatment, the five-year survival rate for OSCC patients remains under 50%. Early diagnosis can greatly improve the chances of survival. Therefore, understanding the development and transformation of OSCC and developing new diagnostic methods is crucial...
February 28, 2024: Bioengineering
https://read.qxmd.com/read/38456006/the-3-dimensional-printing-for-dental-tissue-regeneration-the-state-of-the-art-and-future-challenges
#5
REVIEW
Fengxiao Zhao, Zhijun Zhang, Weihua Guo
Tooth loss or damage poses great threaten to oral and general health. While contemporary clinical treatments have enabled tooth restoration to a certain extent, achieving functional tooth regeneration remains a challenging task due to the intricate and hierarchically organized architecture of teeth. The past few decades have seen a rapid development of three-dimensional (3D) printing technology, which has provided new breakthroughs in the field of tissue engineering and regenerative dentistry. This review outlined the bioactive materials and stem/progenitor cells used in dental regeneration, summarized recent advancements in the application of 3D printing technology for tooth and tooth-supporting tissue regeneration, including dental pulp, dentin, periodontal ligament, alveolar bone and so on...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38441700/dilatedtoothsegnet-tooth-segmentation-network-on-3d-dental-meshes-through-increasing-receptive-vision
#6
JOURNAL ARTICLE
Lucas Krenmayr, Reinhold von Schwerin, Daniel Schaudt, Pascal Riedel, Alexander Hafner
The utilization of advanced intraoral scanners to acquire 3D dental models has gained significant popularity in the fields of dentistry and orthodontics. Accurate segmentation and labeling of teeth on digitized 3D dental surface models are crucial for computer-aided treatment planning. At the same time, manual labeling of these models is a time-consuming task. Recent advances in geometric deep learning have demonstrated remarkable efficiency in surface segmentation when applied to raw 3D models. However, segmentation of the dental surface remains challenging due to the atypical and diverse appearance of the patients' teeth...
March 5, 2024: J Imaging Inform Med
https://read.qxmd.com/read/38436947/noninferiority-of-silver-diamine-fluoride-vs-sealants-for-reducing-dental-caries-prevalence-and-incidence-a-randomized-clinical-trial
#7
JOURNAL ARTICLE
Ryan Richard Ruff, Tamarinda J Barry Godín, Richard Niederman
IMPORTANCE: Dental caries is the world's most prevalent noncommunicable disease and a source of health inequity; school dental sealant programs are a common preventive measure. Silver diamine fluoride (SDF) may provide an alternative therapy to prevent and control caries if shown to be noninferior to sealant treatment. OBJECTIVE: To determine whether school-based application of SDF is noninferior to dental sealants and atraumatic restorative treatment (ART) in the prevalence of dental caries...
March 4, 2024: JAMA Pediatrics
https://read.qxmd.com/read/38419994/a-narrative-review-of-minimally-invasive-techniques-in-restorative-dentistry
#8
REVIEW
Yasir Alyahya
This narrative review aimed to provide a comprehensive overview of minimal invasive dentistry (MID) by synthesizing relevant articles obtained from various sources, including electronic databases such as PubMed, SCOPUS, EMBASE, the COCHRANE library, and Science Direct, as well as through manual searches of cross-references and textbooks. The search employed MeSH terms and keywords related to MID, such as "minimally invasive dentistry," "atraumatic restorative treatment (ART)," "MID," and "minimum intervention dentistry...
February 2024: Saudi Dental Journal
https://read.qxmd.com/read/38391901/evaluating-glass-ionomer-cement-longevity-in-the-primary-and-permanent-teeth-an-umbrella-review
#9
REVIEW
Alessandro Panetta, Pedro Lopes, Tatiane Fernandes Novaes, Rute Rio, Gustavo Vicentis Oliveira Fernandes, Anna Carolina Volpi Mello-Moura
The aim of this umbrella review was to evaluate the longevity of glass ionomer cement (GIC) as a restorative material for primary and permanent teeth. Research in the literature was conducted in three databases (MedLine/PubMed, Web of Science, and Scopus). The inclusion criteria were: (1) to be a systematic review of clinical trials that (2) evaluated the clinical longevity of GICs as a restorative material in primary and/or permanent teeth; the exclusion criteria were: (1) not being a systematic review of clinical trials; (2) not evaluating longevity/clinical performance of GICs as a restorative material; and (3) studies of dental restorative materials in teeth with enamel alterations, root caries, and non-carious cervical lesions...
February 19, 2024: Journal of Functional Biomaterials
https://read.qxmd.com/read/38345861/tempospatially-confined-catalytic-membranes-for-advanced-water-remediation
#10
REVIEW
Na Lu, Fu Liu
The application of homogeneous catalysts in water remediation is limited by factors such as their excessive chemical and energy input, weak regenerability, and potential leaching. Heterogeneous catalytic membranes (CMs) offer a new approach to facilitating efficient, selective, and continuous pollutant degradation. Thus, integrating membranes and continuous filtration with heterogeneous advanced oxidation processes can promote thermodynamic and kinetic mass transfers in spatially confined intrapores and facilitate diffusion-reaction processes...
February 12, 2024: Advanced Materials
https://read.qxmd.com/read/38343817/use-of-dental-care-services-among-adolescents-living-with-hiv-on-antiretroviral-treatment-in-kampala-uganda-a-cross-sectional-study
#11
Maria Gorretti Nakyonyi, Nancy Birungi, Catherine Lutalo Mwesigwa, Anne Nordrehaug Åstrøm
Objective The main purpose of this study to assess the prevalence and socio-behavioural determinants of ever-use of dental care services among the adolescents aged 10-18 years, living with HIV on Antiretroviral treatment (ART), attending selected HIV clinics in Kampala, Uganda. Methods A cross-sectional study was carried out between March and September 2020. The study conveniently recruited 154 adolescents between 10-18 years from 4 specific HIV clinics in Kampala. The Andersen's behavioral model guided the selection of variables in terms of ever use of dental care services as the outcome- and predisposing, enabling, need related factors and dental health related behavior as exposure variables...
January 25, 2024: Research Square
https://read.qxmd.com/read/38319614/dentistry-in-the-centuries-a-historical-overview
#12
JOURNAL ARTICLE
Andrea Ballini, Ioannis A Charitos, Mario Dioguardi, Alessandro Motta, Lorenzo Lo Muzio, Maria E Bizzoca, Vito C A Caponio, Michele DI Cosola
The began of the dentistry as medicine's concept has a long history dating back to 7000 BCE, making it one of the earliest medical specialties. In its early days, dental diseases were often attributed to supernatural causes like "evil spirits" and "tooth worms." However, today, dentistry leverages cutting-edge technologies, including artificial intelligence, for diagnosis and treatment. This journey reflects the remarkable progress made in the field. Despite these advancements, there is still room for improvement in integrating dental knowledge and skills with medical science and engineering backgrounds...
February 6, 2024: Minerva dental and oral science
https://read.qxmd.com/read/38287973/salivary-cathelicidin-ll-37-in-children-and-adolescents-living-with-hiv
#13
JOURNAL ARTICLE
Ana Lucia Seminario, Ashley E Karczewski, Whasun Chung, Yan Wang, Dalton Wamalwa, Sarah Benki-Nugent, Grace John-Stewart, Jennifer A Slyker, Arthur Kemoli
INTRODUCTION: Human cathelicidin LL-37 is a salivary antimicrobial peptide (AMP) with broad-spectrum activity against oral diseases, but few studies have assessed its role in children and adolescents living with HIV (CALHIV). We assessed salivary LL-37 levels and correlates in a long-term cohort of Kenyan CALHIV followed since antiretroviral therapy (ART) initiation. METHODS: Saliva was collected from 76 CALHIV who were recruited from two ongoing pediatric HIV studies in Nairobi, Kenya...
2024: Biomedicine Hub
https://read.qxmd.com/read/38283469/a-narrative-review-of-osteonecrosis-of-the-jaw-what-a-clinician-should-know
#14
REVIEW
Swati Sharma, Rama Shankar, B Sarat Ravi Kiran, Rohit Breh, Shitun Sarangi, Amitabh Kumar Upadhyay
Medication-related osteonecrosis of the jaw (MRONJ) is an uncommon complication of antiresorptive therapy (ART) in patients receiving higher and more frequent doses of osteoclast inhibitors. The jaws are the most common site, as they have high bone turnover. The oral structures are exposed to various types of stresses, like mastication and dental diseases, which lead to microtrauma and increased bone remodeling. The hallmark feature of MRONJ is the area of exposed, necrotic, nonhealing, asymptomatic bone for more than eight weeks...
December 2023: Curēus
https://read.qxmd.com/read/38255446/designing-composite-stimuli-responsive-hydrogels-for-wound-healing-applications-the-state-of-the-art-and-recent-discoveries
#15
REVIEW
Anna Michalicha, Anna Belcarz, Dimitrios A Giannakoudakis, Magdalena Staniszewska, Mariusz Barczak
Effective wound treatment has become one of the most important challenges for healthcare as it continues to be one of the leading causes of death worldwide. Therefore, wound care technologies significantly evolved in order to provide a holistic approach based on various designs of functional wound dressings. Among them, hydrogels have been widely used for wound treatment due to their biocompatibility and similarity to the extracellular matrix. The hydrogel formula offers the control of an optimal wound moisture level due to its ability to absorb excess fluid from the wound or release moisture as needed...
January 5, 2024: Materials
https://read.qxmd.com/read/38203968/biomedical-applications-of-titanium-alloys-a-comprehensive-review
#16
REVIEW
Elia Marin, Alex Lanzutti
Titanium alloys have emerged as the most successful metallic material to ever be applied in the field of biomedical engineering. This comprehensive review covers the history of titanium in medicine, the properties of titanium and its alloys, the production technologies used to produce biomedical implants, and the most common uses for titanium and its alloys, ranging from orthopedic implants to dental prosthetics and cardiovascular devices. At the core of this success lies the combination of machinability, mechanical strength, biocompatibility, and corrosion resistance...
December 25, 2023: Materials
https://read.qxmd.com/read/38188639/organic-antibacterial-modifications-of-high-viscosity-glass-ionomer-cement-for-atraumatic-restorative-treatment-a-review
#17
REVIEW
Damodar Hegde, Baranya Shrikrishna Suprabha, Arathi Rao
High viscosity glass ionomer cement (HVGIC) has been employed as a restorative material for Atraumatic Restorative Treatment (ART). As residual caries persist after caries removal in ART, the antibacterial activity of HVGIC gains importance. Organic and inorganic substances with antibacterial properties have been incorporated into HVGIC over the years, and their effects on the antibacterial and physical properties have been studied. The objective of this paper is to review the various alterations made to HVGIC using organic compounds, their effect on the antibacterial activity, and the physical properties of the cement...
December 2024: Japanese Dental Science Review
https://read.qxmd.com/read/38138661/additive-manufacturing-of-fe-mn-si-based-shape-memory-alloys-state-of-the-art-challenges-and-opportunities
#18
JOURNAL ARTICLE
Lucia Del-Río, Maria L Nó, Raul Gómez, Leire García-Sesma, Ernesto Urionabarrenetxea, Pablo Ortega, Ane M Mancisidor, Maria San Sebastian, Nerea Burgos, Jose M San Juan
Additive manufacturing (AM) constitutes the new paradigm in materials processing and its use on metals and alloys opens new unforeseen possibilities, but is facing several challenges regarding the design of the microstructure, which is particularly awkward in the case of functional materials, like shape memory alloys (SMA), as they require a robust microstructure to withstand the constraints appearing during their shape change. In the present work, the attention is focused on the AM of the important Fe-Mn-Si-based SMA family, which is attracting a great technological interest in many industrial sectors...
December 5, 2023: Materials
https://read.qxmd.com/read/38078023/children-s-anxiety-levels-and-their-perspectives-on-dental-experiences-in-students-clinical-evaluation
#19
JOURNAL ARTICLE
Silvia Ortiz, Minn Yoon, Monica Gibson, Ida Kornerup, Mehdi S Zeinabadi, Hollis Lai
AIM: The purpose of this study is to present a framework for the potential implementation of children's anxiety levels and perspectives of their experiences receiving treatment from dental students through interviews and drawing into the clinical assessment of dental students. MATERIALS AND METHODS: A total of 51 patients between the ages of 5 and 8 years were included in the study. Pulp therapy and/or restorative treatment was performed during the first therapeutic session for all participants...
September 2023: International Journal of Clinical Pediatric Dentistry
https://read.qxmd.com/read/37988046/occupations-associated-with-treatment-seeking-and-biopsychosocial-functioning-at-a-tertiary-orofacial-pain-clinic-a-cross-sectional-study
#20
JOURNAL ARTICLE
Linda Sangalli, Anna Alessandri-Bonetti, Flavia P Kapos, Ian A Boggero
BACKGROUND: The aim of this study was to describe whether certain occupations were over- or underrepresented and to compare biopsychosocial functioning by types of occupation and employment status among adults seeking orofacial pain (OFP) treatment. METHODS: The authors extracted self-reported employment status, occupation, and biopsychosocial functioning from initial appointment records of 444 treatment-seeking adults at a university-affiliated OFP clinic. The authors categorized occupations in major and minor occupational groups according to the 2018 Standard Occupational Classification...
November 19, 2023: Journal of the American Dental Association
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