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https://www.readbyqxmd.com/read/28212593/micrornas-and-endometriosis-distinguishing-drivers-from-passengers-in-disease-pathogenesis
#1
Warren B Nothnick
Endometriosis is a disease common in women of reproductive age, characterized by pelvic pain and infertility. Despite its prevalence, the factors and mechanisms which contribute to the development and survival of ectopic lesions remain uncertain. MicroRNAs (miRNAs) are small RNA molecules that regulate posttranscriptional gene regulation which have been proposed to contribute to the pathogenesis of many diseases including that of endometriosis. This review summarizes the results of initial studies describing differentially expressed miRNAs between endometriotic lesion tissue and eutopic endometrium...
February 17, 2017: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/28212408/prevalence-and-associated-comorbidities-of-restless-legs-syndrome-rls-data-from-a-large-population-based-door-to-door-survey-on-19176-adults-in-tehran-iran
#2
Seyed-Mohammad Fereshtehnejad, Arash Rahmani, Mahdiyeh Shafieesabet, Mahshid Soori, Ahmad Delbari, Mohammad Reza Motamed, Johan Lökk
BACKGROUND: Discrepancies have been reported in the prevalence rate of restless legs syndrome (RLS) among different ethnic groups and geographic populations. Furthermore, there are disagreements on determinant factors and associated comorbidities of RLS. We aimed to estimate prevalence of RLS and investigate its associated comorbid conditions and risk factors in a large population-based door-to-door survey. METHODS: Following a multistage random sampling from the households lived in 22 urban districts of Tehran, Iran, 19176 participants with ≥30 years of age were recruited...
2017: PloS One
https://www.readbyqxmd.com/read/28212123/repeatability-study-of-angular-and-linear-measurements-on-facial-morphology-analysis-by-means-of-stereophotogrammetry
#3
Lilian Mendes Andrade, Ana Maria Bettoni Rodrigues da Silva, Laís Valencise Magri, Marco Antônio Moreira Rodrigues da Silva
The aim of this study was to analyze the repeatability in a stereophotogrammetry digital system used for the evaluation of facial morphology. Thirty healthy Brazilian, 18 to 45 years old (26.71 ± 6.53), had 11 reference landmarks marked on their faces by the same examiner and were photographed with an interval of 1 week by the VECTRA M3. Nine angular measurements (nasolabial, mentolabial, nasofrontal, maxillofacial, nasal, maxillary, mandibular, facial convexity, full facial convexity) and 2 linear measurements (middle facial height and lower facial height) were taken...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28212078/demographic-analysis-from-biometric-data-achievements-challenges-and-new-frontiers
#4
Yunlian Sun, Man Zhang, Zhenan Sun, Tieniu Tan
Biometrics is the technique of automatically recognizing individuals based on their biological or behavioral characteristics. Various biometric traits have been introduced and widely investigated, including fingerprint, iris, face, voice, palmprint, gait and so forth. Apart from identity, biometric data may convey various other personal information, covering affect, age, gender, race, accent, handedness, height, weight, etc. Among these, analysis of demographics (age, gender, and race) has received tremendous attention owing to its wide realworld applications, with significant efforts devoted and great progress achieved...
February 14, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28211188/health-status-health-behaviours-and-anxiety-symptoms-of-older-male-caregivers-findings-from-the-concord-health-and-ageing-in-men-project
#5
Chen-Chun Shu, Robert G Cumming, Hal L Kendig, Fiona M Blyth, Louise M Waite, David G Le Couteur, David J Handelsman, Vasi Naganathan
OBJECTIVE: To explore differences between older male caregivers and non-caregivers on health status, health behaviours and well-being, including symptoms of anxiety. METHODS: Data were collected through self-completed questionnaires and face-to-face interviews with 1705 community living men aged ≥70 in the Concord Health and Ageing in Men Project. RESULTS: Eleven per cent of older men were caregivers, of whom 81.7% were looking after their wives or partners...
February 16, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28210943/faces-of-frailty-in-aging-with-hiv-infection
#6
REVIEW
Marion Thurn, Deborah R Gustafson
PURPOSE OF THE REVIEW: The number of adults who are aging successfully and have HIV infection is increasing. More effective antiretroviral therapy (ART) regimens are preventing individuals infected with HIV from reaching end stages of the HIV infection and developing AIDS (acquired immunodeficiency syndrome). However, even at lower viral loads, chronic HIV infection appears to have consequences on aging processes, including the development of frailty. RECENT FINDINGS: Frailty is a term used to describe vulnerability in aging...
February 16, 2017: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/28210911/the-pace-study-lifetime-and-past-year-prevalence-of-headache-in-parma-s-adult-general-population
#7
Arens Taga, Marco Russo, Gian Camillo Manzoni, Paola Torelli
Headache is a widespread disorder and therefore it has a strong impact on quality of life. In the present work we focused on lifetime and past-year prevalence of headache in general and by gender, in a population-based sample in Parma. A total of 904 subjects representative of Parma's adult general population were interviewed face-to-face by a physician from the Parma Headache Centre, using a validated questionnaire. The lifetime prevalence of headache was 69.1%, i.e. 75.8% in women and 60.6% in men; the crude past-year prevalence of headache was 42...
February 17, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28210649/predictive-surgical-reasons-for-failure-after-coracoid-process-transfers
#8
Gregory Gasbarro, Juan Marcelo Giugale, Gilles Walch, Albert Lin
BACKGROUND: Recurrent anterior shoulder instability after coracoid process transfers may be caused by trauma, sports injury, or technical failure of the index procedure. Surgical techniques vary with regard to graft orientation and positioning and number of screws utilized for fixation. PURPOSE: To identify surgical and patient-related factors associated with failure, defined as the need for revision surgery. We hypothesized that failures will occur more commonly with single-screw fixation and graft malposition...
December 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28210534/psychological-adjustment-among-young-puerto-rican-mothers-perceived-partner-support-and-the-moderating-role-of-latino-cultural-orientation
#9
Josefina M Grau, Patricia Castellanos, Erin N Smith, Petra A Duran, Stephanie Silberman, Lauren Wood
Adolescent mothers face multiple stressors and are at risk for experiencing high levels of depressive symptoms and parenting stress. This study examined the interplay of Latino cultural orientation and perceived support from romantic partners in protecting the adjustment of young, low-income, Puerto Rican mothers (N = 103; M age = 18.0 yrs; SD = 1.2) during the second year postpartum. In multivariate analyses, perceived partner support was uniquely and negatively associated with both maternal depressive symptoms and parenting stress...
2017: Journal of Latina/o Psychology
https://www.readbyqxmd.com/read/28210380/emerging-issues-in-adult-female-acne
#10
REVIEW
Joshua A Zeichner, Hillary E Baldwin, Fran E Cook-Bolden, Lawrence F Eichenfield, Sheila Fallon-Friedlander, David A Rodriguez
Acne vulgaris (acne) is a common affliction in adolescence and is a growing problem in adult women. Despite an increasing awareness of acne in the adult female population, there is a lack of good prospective studies assessing the severity, distribution, and differential response to treatment in this group. The long-held dogma that acne in adult women develops on the lower one-third of the face has been recently challenged, and here the authors critically review data from available literature. Moreover, while adult female acne has traditionally been defined as disease in women over age 25, it is the authors' experience that this group is subdivided into women ages 25 to 44 years, separate from perimenopausal patients, ages 45 years and up...
January 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28210228/discriminating-between-anxious-and-non-anxious-subjects-using-the-toronto-hospital-alertness-test
#11
Colin Shapiro, Lucie Truffaut, Sophie Matharan, Valérie Olivier
BACKGROUND: Alertness designates the internal feeling of wakefulness or arousal and is often described to be linked to the level of anxiety. An adequate level of anxiety favoring the alertness needed to deal with a faced specific situation efficiently; too much anxiety can result in failure to process information and respond appropriately. Thus, it would be of interest to verify if different alertness profiles can be observed depending on anxiety level. The Toronto Hospital Alertness Test (THAT) is a test designed to measure alertness...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28209925/the-stress-polarity-pathway-ampk-giv-es-protection-against-metabolic-insults
#12
Pradipta Ghosh
Loss of cell polarity impairs organ development and function; it can also serve as one of the first triggers for oncogenesis. In 2006-2007 two groups simultaneously reported the existence of a special pathway for maintaining epithelial polarity in the face of environmental stressors. In this pathway, AMPK, a key sensor of metabolic stress stabilizes tight junctions, preserves cell polarity, and thereby, maintains epithelial barrier functions. Accumulating evidence since has shown that pharmacologic activation of AMPK by Metformin protects the epithelial barrier against multiple environmental and pathological stressful states and suppresses tumorigenesis...
February 15, 2017: Aging
https://www.readbyqxmd.com/read/28208897/a-validation-of-an-examination-protocol-for-cerebral-visual-impairment-among-children-in-a-clinical-population-in-india
#13
Swetha Sara Philip, Sherab Tsherlinga, Maya Mary Thomas, Gordon N Dutton, Richard Bowman
INTRODUCTION: Cerebral Visual Impairment (CVI) is a leading cause of vision impairment in developed and developing countries due to and increased survival of preterm and low birth weight infants. There are few data concerning the validity of protocols available to diagnose CVI. AIM: This study aimed to document the face, content and construct validity of an assessment protocol namely, a 15-domain, Structured Clinical Question Inventory (SCQI), which is based on structured history taking and clinical examination, for the diagnosis of CVI in a clinical population of India...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208582/nutrients-in-energy-and-one-carbon-metabolism-learning-from-metformin-users
#14
REVIEW
Fedra Luciano-Mateo, Anna Hernández-Aguilera, Noemi Cabre, Jordi Camps, Salvador Fernández-Arroyo, Jose Lopez-Miranda, Javier A Menendez, Jorge Joven
Metabolic vulnerability is associated with age-related diseases and concomitant co-morbidities, which include obesity, diabetes, atherosclerosis and cancer. Most of the health problems we face today come from excessive intake of nutrients and drugs mimicking dietary effects and dietary restriction are the most successful manipulations targeting age-related pathways. Phenotypic heterogeneity and individual response to metabolic stressors are closely related food intake. Understanding the complexity of the relationship between dietary provision and metabolic consequences in the long term might provide clinical strategies to improve healthspan...
February 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28208179/a-quantitative-approach-to-determining-the-ideal-female-lip-aesthetic-and-its-effect-on-facial-attractiveness
#15
Natalie A Popenko, Prem B Tripathi, Zlatko Devcic, Koohyar Karimi, Kathryn Osann, Brian J F Wong
Importance: Aesthetic proportions of the lips and their effect on facial attractiveness are poorly defined. Established guidelines would aid practitioners in achieving optimal aesthetic outcomes during cosmetic augmentation. Objective: To assess the most attractive lip dimensions of white women based on attractiveness ranking of surface area, ratio of upper to lower lip, and dimensions of the lip surface area relative to the lower third of the face. Design, Setting, and Participants: In phase 1 of this study, synthetic morph frontal digital images of the faces of 20 white women ages 18 to 25 years old were used to generate 5 varied lip surface areas for each face...
February 16, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28206958/cause-of-death-in-patients-diagnosed-with-esophageal-cancer-in-sweden-a-population-based-study
#16
Shao-Hua Xie, Karl Wahlin, Jesper Lagergren
BACKGROUND: Esophageal cancer carries a poor prognosis with an overall 5-year survival of less than 20%. However, the causes of death in patients with esophageal cancer have not been well described. METHODS: This nationwide, population-based cohort study included 18 229 esophageal cancer patients who were diagnosed between 1961 and 2014 in Sweden. We assessed the distribution of main causes of death in patients with esophageal cancer and used competing-risks regression to compare the cause-specific risks of death across sexes, ages at diagnosis, and calendar periods of diagnosis...
February 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28206795/maternal-anxiety-predicts-attentional-bias-towards-threat-in-infancy
#17
Santiago Morales, Kayla M Brown, Bradley C Taber-Thomas, Vanessa LoBue, Kristin A Buss, Koraly E Pérez-Edgar
Although cognitive theories of psychopathology suggest that attention bias toward threat plays a role in the etiology and maintenance of anxiety, there is relatively little evidence regarding individual differences in the earliest development of attention bias toward threat. The current study examines attention bias toward threat during its potential first emergence by evaluating the relations between attention bias and known risk factors of anxiety (i.e., temperamental negative affect and maternal anxiety)...
February 16, 2017: Emotion
https://www.readbyqxmd.com/read/28205132/the-city-infant-faces-database-a-validated-set-of-infant-facial-expressions
#18
Rebecca Webb, Susan Ayers, Ansgar Endress
Adults need to be able to process infants' emotional expressions accurately to respond appropriately and care for infants. However, research on processing of the emotional expressions of infant faces is hampered by the lack of validated stimuli. Although many sets of photographs of adult faces are available to researchers, there are no corresponding sets of photographs of infant faces. We therefore developed and validated a database of infant faces, which is available via e-mail request. Parents were recruited via social media and asked to send photographs of their infant (0-12 months of age) showing positive, negative, and neutral facial expressions...
February 15, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28203335/is-the-bayley-scales-of-infant-and-toddler-developmental-screening-test-valid-and-reliable-for-persian-speaking-children
#19
Farin Soleimani, Nadia Azari, Roshanak Vameghi, Firoozeh Sajedi, Soheila Shahshahani, Hossein Karimi, Adis Kraskian, Amin Shahrokhi, Robab Teymouri, Masoud Gharib
BACKGROUND: Advances in perinatal and neonatal care have substantially improved the survival of at-risk infants over the past two decades. OBJECTIVES: The purpose of this study was to assess the reliability and validity of the Bayley Scales of infant and toddler developmental Screening test in Persian-speaking children. METHODS: This was a cross-sectional prospective study of 403 children aged 1 - 42-months. The Bayley scales screening instrument, which consists of five domains (cognitive, receptive, and expressive communication and fine and gross motor items), was used to measure infants' and toddlers' development...
October 2016: Iranian Journal of Pediatrics
https://www.readbyqxmd.com/read/28203069/the-pharmacological-cost-of-copd-during-greek-economic-crisis
#20
Eirini Stafyla, Theodora Kerenidi, Irini Gerogianni, Mary Geitona, Zoe Daniil, Konstantinos I Gourgoulianis
INTRODUCTION: The economic crisis in Greece has substantially affected patients with COPD. The reduction of disposable income has its consequences on patients' ability to afford their medication. The aim of the study is to evaluate the cost of treatment for patients with COPD and the influence of the financial crisis to the patients. METHODS: Data were collected from 189 patients (male: 178, mean age: 70.1±8.4) who visited the outpatient department of University Hospital of Larissa in 2014 and 2015...
2017: International Journal of Chronic Obstructive Pulmonary Disease
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