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Impingement test

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https://www.readbyqxmd.com/read/28410198/specific-changes-in-mitochondrial-lipidome-alter-mitochondrial-proteome-and-increase-the-geroprotective-efficiency-of-lithocholic-acid-in-chronologically-aging-yeast
#1
Anna Leonov, Anthony Arlia-Ciommo, Simon D Bourque, Olivia Koupaki, Pavlo Kyryakov, Paméla Dakik, Mélissa McAuley, Younes Medkour, Karamat Mohammad, Tamara Di Maulo, Vladimir I Titorenko
We have previously found that exogenously added lithocholic acid delays yeast chronological aging. We demonstrated that lithocholic acid enters the yeast cell, is sorted to mitochondria, resides in both mitochondrial membranes, changes the relative concentrations of different membrane phospholipids, triggers changes in the concentrations of many mitochondrial proteins, and alters some key aspects of mitochondrial functionality. We hypothesized that the lithocholic acid-driven changes in mitochondrial lipidome may have a causal role in the remodeling of mitochondrial proteome, which may in turn alter the functional state of mitochondria to create a mitochondrial pattern that delays yeast chronological aging...
March 31, 2017: Oncotarget
https://www.readbyqxmd.com/read/28407167/introduction-of-two-novel-stiffness-parameters-and-interpretation-of-air-puff-induced-biomechanical-deformation-parameters-with-a-dynamic-scheimpflug-analyzer
#2
Cynthia J Roberts, Ashraf M Mahmoud, Jeffrey P Bons, Arif Hossain, Ahmed Elsheikh, Riccardo Vinciguerra, Paolo Vinciguerra, Renato Ambrósio
PURPOSE: To investigate two new stiffness parameters and their relationships with the dynamic corneal response (DCR) parameters and compare normal and keratoconic eyes. METHODS: Stiffness parameters are defined as Resultant Pressure at inward applanation (A1) divided by corneal displacement. Stiffness parameter A1 uses displacement between the undeformed cornea and A1 and stiffness parameter highest concavity (HC) uses displacement from A1 to maximum deflection during HC...
April 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28388318/rotary-and-high-pressure-nozzle-spray-plume-droplet-analysis-for-aerially-applied-mosquito-adulticides-laser-diffraction-characterization
#3
Jonathan A Hornby, Jim Robinson, Milton Sterling
The droplet spectrum of a mosquito adulticide spray plume determines its ability to drift through the target area, impinge on the mosquito, deliver a toxic dose, and the risk of environmental contamination. This paper provides data on droplet spectra produced from 6 nozzles in a high-pressure nozzle spray system and 5 rotary nozzle systems for common mosquito adulticides. Spray plume spectra were measured by laser diffraction. High-pressure nozzles were evaluated at pressures ranging from 500 psi to 6,000 psi...
March 2017: Journal of the American Mosquito Control Association
https://www.readbyqxmd.com/read/28385420/less-is-more-efficacy-of-rapid-3d-t2-space-in-ed-patients-with-acute-atypical-low-back-pain
#4
Nicholas A Koontz, Richard H Wiggins, Megan K Mills, Michael S McLaughlin, Elaine C Pigman, Yoshimi Anzai, Lubdha M Shah
RATIONALE AND OBJECTIVES: Emergency department (ED) patients with acute low back pain (LBP) may present with ambiguous clinical findings that pose diagnostic challenges to exclude cauda equina syndrome (CES). As a proof of concept, we aimed to determine the efficacy of a rapid lumbar spine (LS) magnetic resonance imaging (MRI) screening protocol consisting of a single 3D-T2 SPACE FS (3D-T2 Sampling Perfection with Application optimized Contrasts using different flip angle Evolution fat saturated) sequence relative to conventional LS MRI to exclude emergently treatable pathologies in this complex patient population...
April 3, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28375966/simultaneous-bilateral-hip-arthroscopy-in-adolescent-athletes-with-symptomatic-femoroacetabular-impingement
#5
Mark O McConkey, Vivek Chadayammuri, Tigran Garabekyan, Stephanie W Mayer, Matthew J Kraeutler, Omer Mei-Dan
BACKGROUND: Femoroacetabular impingement represents a common cause of hip pain in adolescents. The purpose of the present study was to evaluate the safety and efficacy of simultaneous bilateral hip arthroscopy for bilateral symptomatic femoroacetabular impingement in adolescent athletes. METHODS: Clinical data were collected in a prospective database on patients who underwent unilateral or simultaneous bilateral hip arthroscopy and included complications, reoperation rate, and return to play time...
April 3, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28373991/semianalytical-solution-for-the-deformation-of-an-elastic-layer-under-an-axisymmetrically-distributed-power-form-load-application-to-fluid-jet-induced-indentation-of-biological-soft-tissues
#6
Minhua Lu, Shuai Huang, Xianglong Yang, Lei Yang, Rui Mao
Fluid-jet-based indentation is used as a noncontact excitation technique by systems measuring the mechanical properties of soft tissues. However, the application of these devices has been hindered by the lack of theoretical solutions. This study developed a mathematical model for testing the indentation induced by a fluid jet and determined a semianalytical solution. The soft tissue was modeled as an elastic layer bonded to a rigid base. The pressure of the fluid jet impinging on the soft tissue was assumed to have a power-form function...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28366611/oscillatory-hydraulic-testing-as-a-strategy-for-napl-source-zone-monitoring-laboratory-experiments
#7
YaoQuan Zhou, Michael Cardiff
Non-aqueous phase liquids (NAPLs) have a complex mode of transport in heterogeneous aquifers, which can result in pools and lenses of NAPLs (the "source zone") that are difficult to detect and can cause long-term contamination via slow dissolution into groundwater (the "dissolved plume"). Characterizing the extent and evolution of NAPL contamination within the source zone is a useful strategy for designing and adapting appropriate remedial actions at many contaminated sites. As a NAPL flows into a given aquifer volume, the effective hydraulic conductivity (K) and specific storage (Ss) of the volume changes associated with the viscosity and compressibility of the impinging fluid, meaning that NAPL movement may be detectable with hydraulic testing...
March 21, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/28359286/the-double-edged-sword-of-re-expression-of-genes-by-hypomethylating-agents-from-viral-mimicry-to-exploitation-as-priming-agents-for-targeted-immune-checkpoint-modulation
#8
REVIEW
Florian Wolff, Michael Leisch, Richard Greil, Angela Risch, Lisa Pleyer
Hypomethylating agents (HMAs) have been widely used over the last decade, approved for use in myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML). The proposed central mechanism of action of HMAs, is the reversal of aberrant methylation in tumor cells, thus reactivating CpG-island promoters and leading to (re)expression of tumor suppressor genes. Recent investigations into the mode of action of azacitidine (AZA) and decitabine (DAC) have revealed new molecular mechanisms that impinge on tumor immunity via induction of an interferon response, through activation of endogenous retroviral elements (ERVs) that are normally epigenetically silenced...
March 31, 2017: Cell Communication and Signaling: CCS
https://www.readbyqxmd.com/read/28339752/testing-shoulder-pain-mapping
#9
Levent Bayam, Rajendra Arumilli, Ian Horsley, Fatma Bayam, Lee Herrington, Lennard Funk
Objective. : A previous study on shoulder pain mapping showed specific pain patterns for common shoulder disorders. This study aimed to test those patterns for accuracy, modify shoulder pain mapping as needed, and observe their reliability and validity. Methods. : This prospective study used a two-step process and was undertaken to determine its potential utility in daily practice. New shoulder pain patients marked their pain, its character and severity, on a custom-made mapping form...
February 22, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28335360/super-hydrophobic-icephobic-coatings-based-on-silica-nanoparticles-modified-by-self-assembled-monolayers
#10
Junpeng Liu, Zaid A Janjua, Martin Roe, Fang Xu, Barbara Turnbull, Kwing-So Choi, Xianghui Hou
A super-hydrophobic surface has been obtained from nanocomposite materials based on silica nanoparticles and self-assembled monolayers of 1H,1H,2H,2H-perfluorooctyltriethoxysilane (POTS) using spin coating and chemical vapor deposition methods. Scanning electron microscope images reveal the porous structure of the silica nanoparticles, which can trap small-scale air pockets. An average water contact angle of 163° and bouncing off of incoming water droplets suggest that a super-hydrophobic surface has been obtained based on the silica nanoparticles and POTS coating...
December 2, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28321187/steps-to-health-in-cognitive-aging-effects-of-physical-activity-on-spatial-attention-and-executive-control-in-the-elderly
#11
Giancarlo Condello, Roberta Forte, Simone Falbo, John B Shea, Angela Di Baldassarre, Laura Capranica, Caterina Pesce
The purpose of this study was to investigate whether physical activity (PA) habits may positively impact performance of the orienting and executive control networks in community-dwelling aging individuals and diabetics, who are at risk of cognitive dysfunction. To this aim, we tested cross-sectionally whether age, ranging from late middle-age to old adulthood, and PA level independently or interactively predict different facets of the attentional performance. Hundred and thirty female and male individuals and 22 adults with type 2 diabetes aged 55-84 years were recruited and their daily PA (steps) was objectively measured by means of armband monitors...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28302429/does-bony-regrowth-occur-after-arthroscopic-femoroplasty-in-a-group-of-young-adolescents-femoroplasty-regrowth-in-adolescents
#12
Itay Perets, Asheesh Gupta, Edwin O Chaharbakhshi, Lyall Ashberg, David E Hartigan, Mary R Close, Benjamin G Domb
PURPOSE: To evaluate femoral head-neck bone regrowth and PROs in skeletally immature patients that underwent arthroscopic femoroplasties over a minimum 2-year period. METHODS: Eleven skeletally immature hips (10 patients) with open femoral head physes underwent femoroplasty between October 2008 and November 2013. Inclusion criteria were minimum 2-year follow-up with patient-reported outcomes (PROs) and radiographs preoperatively, at 2 weeks, and at a minimum of 2 years postoperatively...
March 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28296814/pedicle-screw-safety-how-much-anterior-breach-is-safe-a-cadaveric-and-ct-based-study
#13
Vishal Sarwahi, Monica Payares, Rachel Gecelter, Stephen Wendolowski, Kathleen Maguire, Dan Wang, Beverly Thornhill, Terry Amaral
STUDY DESIGN: Clinical retrospective chart review and basic science study OBJECTIVES.: To determine the safety limits of an anterior/anterorolateral misplaced pedicle screw on CT scan in spinal deformity. SUMMARY OF BACKGROUND DATA: While the limits of medial breaches (<4 mm) are known, the safe limits for anterior/anterolateral breaches in spine deformity are not yet defined. METHODS: This study had two parts. In part I, post-operative CT scans of 165 patients operated on for spine deformity were reviewed for screw misplacement (2800 screws)...
March 14, 2017: Spine
https://www.readbyqxmd.com/read/28271369/important-clinical-descriptors-to-include-in-the-examination-and-assessment-of-patients-with-femoroacetabular-impingement-syndrome-an-international-and-multi-disciplinary-delphi-survey
#14
M P Reiman, K Thorborg, K Covington, C E Cook, P Hölmich
PURPOSE: Determine which examination findings are key clinical descriptors of femoroacetabular impingement syndrome (FAIS) through use of an international, multi-disciplinary expert panel. METHODS: A three-round Delphi survey utilizing an international, multi-disciplinary expert panel operationally defined from international publications and presentations was utilized. RESULTS: All six domains (subjective examination, patient-reported outcome measures, physical examination, special tests, physical performance measures, and diagnostic imaging) had at least one descriptor with 75% consensus agreement for diagnosis and assessment of FAIS...
March 7, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28269573/pose-measurement-of-anterior-pelvic-plane-based-on-inertial-measurement-unit-in-total-hip-replacement-surgeries
#15
Zhe Cao, Shaojie Su, Hong Chen, Hao Tang, Yixin Zhou, Zhihua Wang
In Total Hip Replacement (THR), inaccurate measurement of Anterior Pelvic Plane (APP), which is usually used as a reference plane, will lead to malposition of the acetabular prosthesis. As a result, the risk of impingement, dislocation and wear will increase and the safe range of motion will be limited. In order to acquire the accurate pose of APP, a measurement system is designed in this paper, which includes two parts: one is used to estimate the initial pose of APP and the other is used to trail dynamic motion of APP...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267909/-functional-evaluation-of-the-supraspinatus-tendon-repair-comparing-mini-open-and-open-techniques
#16
C R Mejía-Salazar, M Sierra-Pérez, M Ruiz-Suárez
OBJECTIVE: To compare two surgical techniques to address the painful shoulder syndrome with partial or total supraspinous tendon tear. METHODS: Patients with a diagnosis of complete supraspinous tendon tear who required surgical repair and subacromial decompression. One group was treated with acromioplasty and tendon plasty using an open approach (G1), and the second one underwent arthroscopy with tendon plasty using a minimally-invasive approach (G2). The surgical approach was not decided at random, but was based on the surgeons preference...
July 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28266924/an-evolution-based-strategy-for-engineering-allosteric-regulation
#17
David Pincus, Orna Resnekov, Kimberly Reynolds
Allosteric regulation provides a way to control protein activity at the time scale of milliseconds to seconds inside the cell. An ability to engineer synthetic allosteric systems would be of practical utility for the development of novel biosensors, creation of synthetic cell signaling pathways, and design of small molecule pharmaceuticals with regulatory impact. To this end, we outline a general approach - termed Rational Engineering of Allostery at Conserved Hotspots (REACH) - to introduce novel regulation into a protein of interest by exploiting latent allostery that has been hard-wired by evolution into its structure...
March 6, 2017: Physical Biology
https://www.readbyqxmd.com/read/28259463/properties-of-the-cartilage-layer-from-the-cam-type-hip-impingement-deformity
#18
Andrew D Speirs, Paul E Beaulé, Adrian Huang, Hanspeter Frei
Femoro-acetabular impingement (FAI) is associated with significant acetabular cartilage damage and degenerative arthritis. To understand the contact stress and thus biomechanical mechanisms that may contribute to degeneration, the material behaviour of the cartilage layer is required. The objective of this study is to determine the fibril-reinforced poroelastic properties and composition of cartilage from cam deformities and to compare to those of normal cartilage. Patients undergoing surgical treatment of a symptomatic cam FAI deformity were recruited from the clinical practice of one of the authors...
April 11, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28249855/physical-examination-of-the-elbow-what-is-the-evidence-a-systematic-literature-review
#19
REVIEW
Elisa L Zwerus, Matthijs P Somford, François Maissan, Jelle Heisen, Denise Eygendaal, Michel Pj van den Bekerom
OBJECTIVE: Primary to provide an overview of diagnostic accuracy for clinical tests for common elbow (sport) injuries, secondary accompanied by reproducible instructions to perform these tests. DESIGN: A systematic literature review according to the PRISMA statement. DATA SOURCES: A comprehensive literature search was performed in MEDLINE via PubMed and EMBASE. ELIGIBILITY CRITERIA: We included studies reporting diagnostic accuracy and a description on the performance for elbow tests, targeting the following conditions: distal biceps rupture, triceps rupture, posteromedial impingement, medial collateral ligament (MCL) insufficiency, posterolateral rotatory instability (PLRI), lateral epicondylitis and medial epicondylitis...
March 1, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28245972/static-and-dynamic-shoulder-imaging-to-predict-initial-effectiveness-and-recurrence-after-ultrasound-guided-subacromial-corticosteroid-injections
#20
Ke-Vin Chang, Wei-Ting Wu, Der-Sheng Han, Levent Özçakar
OBJECTIVE: To explore factors contributing to initial effectiveness and recurrence after ultrasound (US)-guided subacromial corticosteroid injections by assessing clinical measurements as well as static and dynamic shoulder US images. DESIGN: Retrospective cohort study. SETTING: Rehabilitation outpatient clinic. PARTICIPANTS: Adults with shoulder pain referred for injection therapy. INTERVENTIONS: US-guided subacromial corticosteroid injection...
February 25, 2017: Archives of Physical Medicine and Rehabilitation
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