keyword
MENU ▼
Read by QxMD icon Read
search

Lipoprotein

keyword
https://www.readbyqxmd.com/read/28738487/-circadian-blood-pressure-characteristics-in-hospitalized-unstable-angina-pectoris-patients-with-hypertension
#1
W Zhang, H Zhu, S Y Yao, Y Li, J Liu, H Xue
Objective: To define the characteristic of circadian rhythm of blood pressure in unstable angina pectoris (UAP)patients with hypertension and its effects on the cardiovascular events. Methods: It was a prospective study.Based on coronary angiographic results, 742 consecutive hospitalized UAP patients with hypertension and 89 consecutive hospitalized hypertensive patients were recruited between September 2014 and December 2015 in this study. Clinical data and the results of 24-hour ambulatory blood pressure monitoring (ABPM) were analyzed...
July 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28738484/-correlation-between-serum-inflammatory-cytokine-levels-and-fibrous-cap-thickness-of-fibrofatty-plaque-in-coronary-culprit-lesions
#2
Y Zhong, F Ye, W You, Z M Wu
Objective: To identify the correlation between serum inflammatory cytokine levels including high sensitive C reactive protein (hs-CRP) and lipoprotein associated phospholipase (Lp-PLA2) and the fibrous cap thickness of fibrofatty plaque in coronary culprit lesions. Methods: Clinical data of 117 patients with selective coronary artery angiography diagnosed coronary artery disease admitted to our hospital from January 2015 to January 2016 were retrospective analyzed. According to type of coronary disease, patients were divided into 3 subgroups: SAP group (containing 47 stable angina patients), UAP group (containing 52 unstable angina patients), and NSTEMI group(containing 18 acute non ST segment elevation myocardial infarction patients)...
July 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28738463/-a-cross-sectional-study-on-dyslipidemia-in-migrants-in-inner-mongolia-autonomous-region
#3
T Zhang, Q Zhou, Y G Qian, J Zhou, S J Wu, P Y Wang, A P Liu
Objective: To investigate the prevalence of dyslipidemia in migrants in Inner Mongolia Autonomous Region. Methods: A stratified multi-stage cluster equal size sampling was performed among the migrants aged ≥18 years who were engaged in manufacturing, wholesale retail, accommodation and catering service, social service, construction and other and 1 501 migrants from five area in Inner Mongolia Autonomous Region was investigated by means of questionnaires survey, physical measurements and laboratory detection...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28738359/predictors-of-subclinical-inflammatory-obesity-plasma-levels-of-leptin-very-low-density-lipoprotein-cholesterol-and-cd14-expression-of-cd16-monocytes
#4
Fernanda Leite, Ângela Leite, Ana Santos, Margarida Lima, Joselina Barbosa, Marco Cosentino, Laura Ribeiro
OBJECTIVE: Predictors of subclinical inflammatory obesity (SIO) can be important tools for early therapeutic interventions in obesity-related comorbidities. Waist circumference (WC) and BMI have different SIO sensitivity. We aimed to i) identify SIO predictors and ii) investigate whether CD16+ monocytes are associated with BMI- (generally) or WC-defined (centrally) obesity. METHODS: Anthropometric and metabolic/endocrine (namely catecholamines, adrenaline and noradrenaline) parameters were evaluated, and CD16+ monocytes were studied by flow cytometry in the peripheral blood from 63 blood donors, and compared and correlated to each other...
July 22, 2017: Obesity Facts
https://www.readbyqxmd.com/read/28738148/biofunctional-polymer-lipid-hybrid-high-density-lipoprotein-mimicking-nanoparticles-loading-anti-mir155-for-combined-antiatherogenic-effects-on-macrophages
#5
Jing Lu, Yi Zhao, Xiaoju Zhou, Jian Hua He, Yun Yang, Cuiping Jiang, Zitong Qi, Wenli Zhang, Jianping Liu
A biofunctional polymer-lipid hybrid high density lipoprotein-mimicking nanoparticle (HNP) loading anti-miR155 was constructed for combined antiatherogenic effects on macrophages. The HNP consisted of an anti-miR155 core condensed by acid-labile polyethylenimine (acid-labile PEI) polymers and a lipid bilayer coat that was decorated with apolipoprotein A-1, termed acid-labile PEI/HNP. The acid-labile PEI was synthesized with low molecular weight PEI and glutaraldehyde to reduce the cytotoxicity and facilitate nucleic acids escaping from acidic endolysosomes...
July 24, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28737859/association-between-dietary-glycemic-load-and-metabolic-syndrome-in-obese-children-and-adolescents
#6
Angela Cornejo-Monthedoro, Isel Negreiros-Sánchez, Carlos Del Águila, Marlit Ysla-Marquillo, Percy Mayta-Tristán
OBJETIVE: To study the association between the metabolic syndrome (MS) and the glycemic load (GL) of food intake among obese children and adolescents seen in consultation by the endocrinology team in a pediatric referral hospital in Lima, Peru. POPULATION AND METHOD: Cross-sectional study among obese children and adolescents (body mass index ≥ 95 percentile), 10-15 years old. The MS was classified according to criteria of the International Diabetes Federation...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28737258/preclinical-alterations-in-myocardial-microstructure-in-people-with-metabolic-syndrome
#7
Jennifer E Ho, Youssef Rahban, Harpaul Sandhu, Pranoti G Hiremath, Nir Ayalon, Fuzhong Qin, Alejandro J Perez, Jill Downing, Deepa M Gopal, Susan Cheng, Wilson S Colucci
OBJECTIVE: Metabolic syndrome (MetS) can lead to myocardial fibrosis, diastolic dysfunction, and eventual heart failure. This study evaluated alterations in myocardial microstructure in people with MetS by using a novel algorithm to characterize ultrasonic signal intensity variation. METHODS: Among 254 participants without existing cardiovascular disease (mean age 42 ± 11 years, 75% women), there were 162 with MetS, 47 with obesity without MetS, and 45 nonobese controls...
July 24, 2017: Obesity
https://www.readbyqxmd.com/read/28737243/investigating-the-genetic-regulation-of-the-expression-of-63-lipid-metabolism-genes-in-the-pig-skeletal-muscle
#8
R González-Prendes, R Quintanilla, M Amills
A comprehensive and systematic view of the genetic regulation of lipid metabolism genes is still lacking in pigs. Herewith, we have investigated the genetic regulation of 63 porcine genes with crucial roles in the uptake, transport, synthesis and catabolism of lipids. With this aim, we have performed an expression QTL (eQTL) scan in 104 pigs with available genotypes for the Illumina Porcine SNP60 chip and microarray measurements of gene expression in the gluteus medius muscle. Analysis of the data with gemma software revealed 13 cis- and 18 trans-eQTL modulating the expression of 19 loci...
July 24, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28736830/pcsk9-in-context-a-contemporary-review-of-an-important-biological-target-for-the-prevention-and-treatment-of-atherosclerotic-cardiovascular-disease
#9
REVIEW
Michael M Page, Gerald F Watts
Proprotein convertase subtilisin/kexin type 9 (PCSK9) and the identification of its critical role in lipoprotein metabolism has rapidly led to the development of PCSK9 inhibition with monoclonal antibodies (mAbs). PCSK9 mAbs are already in limited clinical use and are the subject of major cardiovascular outcomes trials, which if universally positive could see much wider clinical application of these agents. Patients with familial hypercholesterolaemia are the most obvious candidates for these drugs, but other patients with elevated cardiovascular risk, statin intolerance or hyperlipoproteinaemia(a) may also benefit...
July 24, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28736372/-clinical-value-of-apolipoprotein-b-versus-low-density-lipoprotein-cholesterol-in-assessing-risks-of-coronary-artery-disease
#10
Si Chen, Jin-Zhen Zhao, Jing Hu, Zhi-Gang Guo
OBJECTIVE: To compare the value of apolipoprotein B (apoB) and low-density lipoprotein cholesterol (LDL-C) in assessing the risk of coronary heart disease in patients with inconsistent apoB and LDL-C levels. METHODS: In a total of 603 patients undergoing coronary angiography, apoB and LDL-C levels were categorized into high and low levels relative to the median levels of apoB and LDL-C, based on which the patients were divided into 4 groups with low apoB/low LDL-C, low apoB/high LDL-C, high apoB/low LDL-C, or high apoB/high LDL-C...
July 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28735838/cardiovascular-effects-of-air-pollution
#11
REVIEW
Thomas Bourdrel, Marie-Abèle Bind, Yannick Béjot, Olivier Morel, Jean-François Argacha
Air pollution is composed of particulate matter (PM) and gaseous pollutants, such as nitrogen dioxide and ozone. PM is classified according to size into coarse particles (PM10), fine particles (PM2.5) and ultrafine particles. We aim to provide an original review of the scientific evidence from epidemiological and experimental studies examining the cardiovascular effects of outdoor air pollution. Pooled epidemiological studies reported that a 10μg/m(3) increase in long-term exposure to PM2.5 was associated with an 11% increase in cardiovascular mortality...
July 20, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28735818/curcuminoids-modify-lipid-profile-in-type-2-diabetes-mellitus-a-randomized-controlled-trial
#12
Yunes Panahi, Nahid Khalili, Ebrahim Sahebi, Soha Namazi, Željko Reiner, Muhammed Majeed, Amirhossein Sahbekar
BACKGROUND: Type 2 diabetes (T2D) is an established risk factor for cardiovascular disease (CVD) and is associated with disturbed metabolism of lipids and lipoproteins. Curcuminoids are natural products with anti-diabetic and lipid-modifying actions but their efficacy in improving dyslipidemia in diabetic individuals has not been sufficiently studied. OBJECTIVE: To investigate the efficacy of supplementation with curcuminoids, plus piperine as an absorption enhancer, in improving serum lipids in patients with T2D...
August 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28735759/associations-between-tooth-loss-and-prognostic-biomarkers-and-the-risk-for-cardiovascular-events-in-patients-with-stable-coronary-heart-disease
#13
Ola Vedin, Emil Hagström, Ollie Östlund, Alvaro Avezum, Andrzej Budaj, Marcus D Flather, Robert A Harrington, Wolfgang Koenig, Joseph Soffer, Agneta Siegbahn, Philippe Gabriel Steg, Ralph A H Stewart, Lars Wallentin, Harvey D White, Claes Held
BACKGROUND: Underlying mechanisms behind the hypothesized relationship between periodontal disease (PD) and coronary heart disease (CHD) have been insufficiently explored. We evaluated associations between self-reported tooth loss- a marker of PD- and prognostic biomarkers in 15,456 (97%) patients with stable CHD in the global STABILITY trial. METHODS AND RESULTS: Baseline blood samples were obtained and patients reported their number of teeth according to the following tooth loss levels: "26-32 (All)" [lowest level], "20-25", "15-19", "1-14", and "No Teeth" [highest level]...
July 17, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28735080/recombinant-truncated-e-protein-as-a-new-vaccine-candidate-against-nontypeable-h-influenzae-its-expression-and-immunogenic-evaluation
#14
Ava Behrouzi, Saeid Bouzari, Farzam Vaziri, Abolfazl Fateh, Parviz Afrough, Atefeh Davoudi Vijeh Motlagh, Seyed Davar Siadat
Protein E (PE) is a conserved entity observed in both nontypeable Haemophilus influenzae (NTHi) and encapsulated H. influenzae. This is a small surface lipoprotein, consisting of only 160 amino acids, involved in the adhesion of H. influenzae to various types of epithelial cells. A 384-bp-long fragment from NTHi PE was cloned into the prokaryotic expression vector pBAD-gIIIA. The recombinant protein was expressed with arabinose and then purified by affinity purification on an Ni-NTA agarose matrix. BALB/c mice were immunized by subcutaneous injection with purified recombinant truncated PE mixed with an alum adjuvant...
July 19, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28734987/bioavailable-and-free-25-hydroxyvitamin-d-and-vitamin-d-binding-protein-in-polycystic-ovary-syndrome-relationships-with-obesity-and-insulin-resistance
#15
Negar Naderpoor, Soulmaz Shorakae, Sally K Abell, Aya Mousa, Anju E Joham, Lisa J Moran, Nigel K Stepto, Poli Mara Spritzer, Helena J Teede, Barbora de Courten
Polycystic ovary syndrome (PCOS) is a common condition characterised by both reproductive and metabolic features (obesity, insulin resistance, diabetes risk). Some evidence suggests that women with PCOS have lower vitamin D levels compared to healthy controls. Vitamin D binding protein (DBP) is the main carrier of vitamin D in circulation and plays an important role in regulating vitamin D concentration and bioavailability for target tissues. To our knowledge, no previous studies have examined DBP, bioavailable and free 25-hydroxyvitamin D (25(OH)D) in women with PCOS...
July 19, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28734952/potential-predictive-role-of-lipid-peroxidation-markers-for-type-2-diabetes-in-the-tunisian-population
#16
Houda Bouhajja, Faten Hadj Kacem, Rania Abdelhedi, Marwa Ncir, Jordan D Dimitrov, Rim Marrakchi, Kamel Jamoussi, Ahmed Rebai, Abdelfattah El Feki, Mohamed Abid, Hammadi Ayadi, Srini V Kaveri, Mouna Mnif-Feki, Noura Bougacha-Elleuch
OBJECTIVES: We evaluated the potential clinical relevance of malondialdehyde (MDA) and autoantibodies to copper oxidized low-density lipoprotein (CuOx-LDL) in type 2 diabetes occurrence. METHODS: This cross-sectional study enrolled 69 normoglycemic subjects, 18 prediabetic patients and 108 type 2 diabetes patients. MDA concentration was assessed spectrophotometrically. Plasma IgG, IgA and IgM levels to CuOx-LDL were determined by ELISA. RESULTS: Plasma MDA levels were considerably higher in obese, prediabetic and type 2 diabetes subjects compared to controls...
July 19, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28734827/multi-omics-analyses-of-starvation-responses-reveal-a-central-role-for-lipoprotein-metabolism-in-acute-starvation-survival-in-c-%C3%A2-elegans
#17
Eva Bang Harvald, Richard R Sprenger, Kathrine Brændgaard Dall, Christer S Ejsing, Ronni Nielsen, Susanne Mandrup, Alejandro Brenes Murillo, Mark Larance, Anton Gartner, Angus I Lamond, Nils J Færgeman
Starvation causes comprehensive metabolic changes, which are still not fully understood. Here, we used quantitative proteomics and RNA sequencing to examine the temporal starvation responses in wild-type Caenorhabditis elegans and animals lacking the transcription factor HLH-30. Our findings show that starvation alters the abundance of hundreds of proteins and mRNAs in a temporal manner, many of which are involved in central metabolic pathways, including lipoprotein metabolism. We demonstrate that premature death of hlh-30 animals under starvation can be prevented by knockdown of either vit-1 or vit-5, encoding two different lipoproteins...
July 12, 2017: Cell Systems
https://www.readbyqxmd.com/read/28734591/increased-inflammatory-effect-of-electronegative-ldl-and-decreased-protection-by-hdl-in-type-2-diabetic-patients
#18
Montserrat Estruch, Inka Miñambres, Jose Luis Sanchez-Quesada, Marta Soler, Antonio Pérez, Jordi Ordoñez-Llanos, Sonia Benitez
BACKGROUND AND AIMS: Type 2 diabetic patients have an increased proportion of electronegative low-density lipoprotein (LDL(-)), an inflammatory LDL subfraction present in blood, and dysfunctional high-density lipoprotein (HDL). We aimed at examining the inflammatory effect of LDL(-) on monocytes and the counteracting effect of HDL in the context of type 2 diabetes. METHODS: This was a cross-sectional study in which the population comprised 3 groups (n = 12 in each group): type 2 diabetic patients with good glycaemic control (GC-T2DM patients), type 2 diabetic patients with poor glycaemic control (PC-T2DM), and a control group...
July 13, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28734274/genetic-analysis-of-iranian-patients-with-familial-hypercholesterolemia
#19
Mahdis Ekrami, Maryam Torabi, Soudeh Ghafouri-Fard, Javad Mowla, Bahram Mohammad Soltani, Feyzollah Hashemi-Gorji, Zahra Mohebbi, Mohammad Miryounesi
Background: Familial hypercholesterolemia (FH) is a frequent autosomal dominant disorder of lipoprotein metabolism. This disorder is generally caused by mutations in low-density lipoprotein receptor (LDLR), apolipoprotein B 100 (APOB), and proprotein convertase subtilisin/kexin type 9 (PCSK9) genes. In the present study, we aimed at identifying the common LDLR and APOB gene mutations in an Iranian population. Methods: Eighty unrelated Iranian patients with FH entered the study, based on Simon Broome diagnostic criteria...
July 23, 2017: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/28734203/exenatide-mitigated-diet-induced-vascular-aging-and-atherosclerotic-plaque-growth-in-apoe-deficient-mice-under-chronic-stress
#20
Guang Yang, Yanna Lei, Aiko Inoue, Limei Piao, Lina Hu, Haiying Jiang, Takeshi Sasaki, Hongxian Wu, Wenhu Xu, Chenglin Yu, Guangxian Zhao, Shinyu Ogasawara, Kenji Okumura, Masafumi Kuzuya, Xian-Wu Cheng
BACKGROUND AND AIMS: Exposure to psychosocial stress is a risk factor for cardiovascular disorders. Because the glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) agonist prevents cardiovascular injury, we investigated the beneficial effects and mechanism of the GLP-1 analogue exenatide on stress-related vascular senescence and atherosclerosis in apolipoprotein E-deficient (ApoE(-/-)) mice fed a high-fat (HF) diet. METHODS: ApoE(-/-) mice fed the HF diet were assigned to non-stressed and immobilized-stress groups for 12 weeks...
July 13, 2017: Atherosclerosis
keyword
keyword
7997
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"