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https://www.readbyqxmd.com/read/28527998/molecular-cloning-and-structural-modelling-of-gamma-phospholipase-a2-inhibitors-from-bothrops-atrox-and-micrurus-lemniscatus-snakes
#1
Carina G Picelli, Rafael J Borges, Carlos A H Fernandes, Fabio M Matioli, Carla F C Fernandes, Juliana C Sobrinho, Rudson J Holanda, Luiz S Ozaki, Anderson M Kayano, Leonardo A Calderon, Marcos R M Fontes, Rodrigo G Stábeli, Andreimar M Soares
Phospholipases A2 inhibitors (PLIs) produced by venomous and non-venomous snakes play essential role in this resistance. These endogenous inhibitors may be classified by their fold in PLIα, PLIβ and PLIγ. Phospholipases A2 (PLA2s) develop myonecrosis in snake envenomation, a consequence that is not efficiently neutralized by antivenom treatment. This work aimed to identify and characterize two PLIs from Amazonian snake species, Bothrops atrox and Micrurus lemniscatus. Liver tissues RNA of specimens from each species were isolated and amplified by RT-PCR using PCR primers based on known PLIγ gene sequences, followed by cloning and sequencing of amplified fragments...
May 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28527382/global-burden-of-road-traffic-accidents-in-older-adults-a-systematic-review-and-meta-regression-analysis
#2
Boon Hong Ang, Won Sun Chen, Shaun Wen Huey Lee
PURPOSE OF THE STUDY: This study aims to estimate the burden of road traffic accidents and death among older adults. DESIGN AND METHODS: A systematic literature review was conducted on 10 electronic databases for articles describing Road Traffic Accident(RTA) mortality in older adults until September 2016. A random-effects meta-regression analyses was conducted to estimate the pooled rates of road traffic accidents and death. RESULTS: A total 5018 studies were identified and 23 studies were included...
May 13, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28526902/retroclival-epidural-haematoma-a-diagnosis-to-suspect-report-of-three-cases-and-review-of-the-literature
#3
Gorka Zabalo, Rodrigo Ortega, Jorge Díaz, Alfonso Vázquez, Daniel de Frutos, Juan Carlos García, Idoya Zazpe
Retroclival epidural haematoma (REDH) has been reported infrequently. It is a rare entity which is probably underdiagnosed. It is most commonly seen in the paediatric population and is generally associated with high-velocity injuries. We report three cases of paediatric patients diagnosed with REDHs: two of them secondary to high-energy trauma related to a motor-vehicle accident and the other a low-energy trauma after a slip while playing football. All three patients were managed conservatively by cervical immobilisation with favourable outcome...
May 20, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28526860/risk-factor-analysis-and-idiographic-features-of-mandibular-coronoid-fractures-a-retrospective-case-control-study
#4
Hai-Hua Zhou, Kun Lv, Rong-Tao Yang, Zhi Li, Zu-Bing Li
This study aimed to identify and distinguish various factors that may influence the occurrence of mandibular coronoid fractures. From January 2000 to December 2009, a total of 1131 patients with maxillofacial fractures were enrolled in this statistical study to evaluate the association between mandibular coronoid fractures and other risk factors. Among these patients, 869 had mandibular fractures, and 25 sustained a total of 25 coronoid fractures. More than half (13 of 25 patients, 52%) of the coronoid fractures in these patients were caused by motor vehicle accidents...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28525273/directional-fluid-gating-by-janus-membranes-with-heterogeneous-wetting-properties-for-selective-oil-water-separation
#5
Prashant Gupta, Balasubramanian Kandasubramanian
The rising oil seepage accidents evolved into a global issue necessitating immediate counter measure to abridge its catastrophic repercussions on sensitive marine ecosystem urging innovative techniques for effective oil/water separation. Here, we report surface tailored wettability modified superhydrophobic/superoleophilic Janus membrane by impregnating non-ionic surfactant stabilized nano-sized polytetrafluoroethylene (PTFE) dispersion polymerized via non-fluorinated processing aid onto cotton substrate using Meyer rod coating technique, exhibiting excellent separation efficiency up to 98% with various petroleum products and retaining its intrinsic properties for at least 30 recurrences...
May 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28523083/association-of-midfacial-fractures-with-ophthalmic-injury
#6
REVIEW
Constantinus Politis, Alexandra Kluyskens, Titiaan Dormaar
The aim of this study is to evaluate the incidence of ophthalmic complications following midfacial fractures and investigate its relation to surgical or nonsurgical treatment. This article is a retrospective study, describing the spectrum and incidence of ophthalmic injury in 106 patients presenting with midfacial fractures at the Department of Oral and Maxillofacial Surgery of the University Hospitals Leuven over a period of 16 months (January 2013 to April 2014). The mean age of the patients was 45.6 years with a gender distribution of 68 men and 38 women...
June 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28523046/healthy-lifestyle-behavior-of-employees-in-small-and-medium-sized-enterprises-in-aydin-turkey
#7
Safiye Ozvurmaz, Aliye Mandiracioglu
OBJECTIVE: To determine healthy lifestyle behavior and affecting risk factors in workers at small and medium-sized enterprises from four different sectors in Aydin, Turkey. METHODS: This cross-sectional study was conducted at four different small and medium-sized enterprises in Aydin, Turkey and 264 employees participated in the study. A questionnaire was used for data collection. It consisted of questions about socio-demographic features (age, gender, marital status, education, perceived income, occupation and having children), health status, and medical history, medication use, having occupational accidents and occupational health and safety...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28522790/the-influence-of-rifaximin-on-diverticulitis-rate-and-quality-of-life-in-patients-with-diverticulosis
#8
Tomasz Banasiewicz, Wojciech Francuzik, Adam Bobkiewicz, Łukasz Krokowicz, Maciej Borejsza-Wysocki, Jacek Paszkowski, Adam Studniarek, Piotr Krokowicz, Marcin Grochowalski, Marek Szczepkowski, Zbigniew Lorenc
Diverticulosis, its associated symptoms and complications are one of the most common pathologies of the gastrointestinal tract in more economically developed countries. Presence of diverticuli and their clinical consequences can be divided into four categories: 1) diverticulosis, i.e. an asymptomatic presence of diverticuli that are usually found by accident 2) symptomatic uncomplicated diverticulosis 3) diverticulitis (acute uncomplicated diverticulitis) 4) complications of diverticulitis (conditions requiring hospital stay)...
February 28, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28522784/penetrating-trauma-of-the-face-and-facial-skeleton-a-case-series-of-six-patients
#9
Aneta Neskoromna-Jędrzejczak, Katarzyna Bogusiak, Aleksander Przygoński, Bogusław Antoszewski
Penetrating traumas of the facial skeleton are relatively rare; however, they can be dangerous and even life-threatening. The epidemiology of facial skeleton trauma is diverse and depends on the affected region, age, and the kind of foreign body that caused the injury. In Poland, the most common cause of penetrating traumas are accidents and assaults, and only rarely accidents are related to improper use of firecrackers or fireworks. The aim of this study is to present a literature review and our own experience with penetrating traumas of the face and the facial part of the cranium...
February 28, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28522305/the-girona-territori-cardioprotegit-project-performance-evaluation-of-public-defibrillators
#10
Pablo Loma-Osorio, Maria Nuñez, Jaime Aboal, Daniel Bosch, Pau Batlle, Ester Ruiz de Morales, Rafael Ramos, Josep Brugada, Hisao Onaga, Alex Morales, Josep Olivet, Ramon Brugada
INTRODUCTION AND OBJECTIVES: In recent years, public access defibrillation programs have exponentially increased the availability of automatic external defibrillators (AED) in public spaces but there are no data on their performance in our setting. We conducted a descriptive analysis of the performance of AED since the launch of a public defibrillation program in our region. METHODS: A retrospective analysis was conducted of electrocardiographic tracings and the performance of AED in a public defibrillation program from June 2011 to June 2015 in the province of Girona, Spain...
May 15, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28521903/motorcycle-related-hospitalizations-of-the-elderly
#11
Ching-Hua Hsieh, Hang-Tsung Liu, Shiun-Yuan Hsu, Hsiao-Yun Hsieh, Yi-Chun Chen
BACKGROUND: To investigate the injury pattern, mechanisms, severity, and mortality of the elderly hospitalized for treatment of trauma following motorcycle accidents. METHODS: Motorcycle-related hospitalization of 994 elderly and 5078 adult patients from the 16,548 hospitalized patients registered in the Trauma Registry System between January 1, 2009 and December 31, 2013. RESULTS: The motorcycle-related elderly trauma patients had higher injury severity, less favorable outcomes, higher proportion of patients admitted to the intensive care unit (ICU), prolonged hospital and ICU stays and higher mortality than those adult motorcycle riders...
April 2017: Biomedical Journal
https://www.readbyqxmd.com/read/28521902/differences-between-the-sexes-in-motorcycle-related-injuries-and-fatalities-at-a-taiwanese-level-i-trauma-center
#12
Ching-Hua Hsieh, Shiun-Yuan Hsu, Hsiao-Yun Hsieh, Yi-Chun Chen
BACKGROUND: Female patients present with unique physiological and behavioral characteristics compared to male patients. The aim of this study was to investigate and compare the injury patterns, injury characteristics, and mortality of male and female patients hospitalized for treatment of motorcycle accident-related trauma in a level I trauma center. METHODS: Retrospective analysis of motorcycle-related injuries from the Trauma Registry System was performed to identify and compare 4028 male and 2919 female patients hospitalized for treatment between January 1, 2009 and December 31, 2013...
April 2017: Biomedical Journal
https://www.readbyqxmd.com/read/28521593/use-of-high-frequency-percussive-ventilation-to-expand-organ-donor-pool
#13
Francis Benn, Ashwad Afzal, Berhane Worku, Felix Khusid, Bashar H Fahoum, Iosif Gulkarov
A 34-year-old woman was brought in to the emergency department after a motor vehicle accident. She had signs of traumatic head injury with Glasgow Coma Scale score of 3, and her neurological examination was consistent with brain death. She was persistently hypoxic on conventional mechanical ventilation and high-frequency percussive ventilation was initiated. The patient's oxygenation improved and was sustained long enough to provide time for organ procurement. This is the first case portraying high-frequency percussive ventilation as a bridge for donors failing on conventional mechanical ventilation...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28521252/trauma-type-as-a-conditional-risk-factor-for-posttraumatic-stress-disorder-in-a-referred-clinic-sample-of-adolescents
#14
Jani Nöthling, Candice Simmons, Sharain Suliman, Soraya Seedat
INTRODUCTION: Traumatic experiences that are varied in type and severity may lead to the development of Posttraumatic Stress Disorder (PTSD). Some trauma types present a higher conditional risk for PTSD owing to their nature and impact on growth and functioning. Few studies have investigated the conditional risk of PTSD in clinic referred adolescents in low- and middle-income countries. The aim of the study was to determine the conditional risk for PTSD based on various trauma types (car accidents, other serious accidents, fires, witnessing a natural disaster, witnessing a violent crime, being confronted with traumatic news, witnessing domestic violence, physical abuse and sexual abuse) and to stratify risk by gender...
May 5, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28518005/safety-considerations-for-medical-staff-and-patients-who-fly-over-water-in-a-helicopter-for-work-or-recreation
#15
Christopher J Brooks, Conor V MacDonald
BACKGROUND: Around 25% of people involved in a helicopter accident in water do not survive. From time to time, physicians and their medical staff are required to fly over water in a helicopter to attend one or more seriously ill patients. Many will have had little or no experience of the issues involved if the helicopter has an accident in the water. Also as Family Practitioners, Aeromedical Examiners, and Flight Surgeons, they are asked to provide advice to patients, travel agents, and airline booking agents about whether an overwater helicopter flight is advisable or not...
April 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28516461/effects-of-high-g-impact-on-physical-electrical-and-optical-characteristics-of-light-emitting-diodes
#16
Xin Wen, Brandon Okraszewski, Pragun Babber, James Cash, Stephen Cain, David Klotzkin
Previously, one of the tools available in automotive or aircraft accident analysis was the examination of the indicator bulbs. Currently, indicator bulbs have been largely replaced by light-emitting diodes (LEDs). Here a series of studies was carried out on impact effects on LEDs to determine whether their properties change after impact, and whether it is related to its working status (lit or unlit). The LEDs were measured before mechanical shock with a series of tests, including current-voltage, current-light, bandwidth, subject to impact ranging from 450 g to 2000 g, and then retested...
May 18, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28515754/traumatic-tension-pneumopericardium-and-amputation-of-the-left-main-bronchus
#17
Lech Krawczyk, Tomasz P Byrczek, Agata Łuczyk, Bogusz D Jagoda, Rafał Kazanowski, Michał J Stasiowski
A 27-year-old woman sustained a blunt chest trauma after a car accident. Computed tomography revealed tension pneumopericardium, bilateral pneumothorax, and a suspected rupture of the left main bronchus. Emergent pericardial needle aspiration was successfully performed. Bronchial amputation was confirmed by bronchofiberoscopy. Despite total detachment of the distal part of the bronchial tree, the ventilation of the left lung was maintained without air leakage by use of pleural drains. Bronchial obturation resulted from the injury, and was effectively treated by bronchoscopic sputum suction at the distal end of the bronchus...
March 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28515563/secondary-eating-disorder-a-reality-case-report-of-post-brain-injury-sequelae
#18
Aparna Das, Deeksha Elwadhi, Manushree Gupta
Traumatic brain injury (TBI) can lead to changes in eating behavior patterns. This report describes the case of a patient with alcohol dependence presenting with behavioral changes and eating disorder following frontal lobe trauma. A 42-year-old male, premorbidly well-adjusted presented with alcohol use in dependent pattern for years. He sustained a subdural hematoma in the frontal lobe following a road traffic accident 10 years back. Post-TBI, the patient, started having low frustration tolerance, aggressive outbursts, disinhibition, difficulty in persisting with tasks, apathy, amotivation, and craving for food with inability to control intake on the sight of food...
March 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28515559/arachnoid-cyst-and-psychosis-the-troublemaker-or-innocent-bystander
#19
Soumitra Das, Arjun Kartha, Sumesh Thoppil Purushothaman, Varun Rajan
Organic underpinning of a psychotic disturbance is often missed. Arachnoid cysts are considered a rare neurological tumor, few of which exhibit any symptomatology. In most cases, they are diagnosed by accident. Literature regarding the coexistence of arachnoid cysts with psychiatric disorders is sparse. Here, we present a case who presented with a typical presentation of psychosis which was not enough for suspecting for an organic etiology.
March 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28515545/traumatic-brain-injury-and-neuropsychiatric-complications
#20
REVIEW
Saeed Ahmed, Hema Venigalla, Hema Madhuri Mekala, Sara Dar, Mudasar Hassan, Shahana Ayub
Traumatic brain injury (TBI) occurs when a blow or jolt to the head or a penetrating injury results in damage to the brain. It is the most frequent cause of hospitalization in young people with a higher prevalence in men. TBI is the leading cause of disability and mortality between the ages 1 and 45. TBI can be caused either by the direct result of trauma or due to a complication of the primary injury. The most common etiological factors for TBI are falls, road traffic accidents, violent physical assaults, and injuries associated with athletic activities...
March 2017: Indian Journal of Psychological Medicine
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