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https://www.readbyqxmd.com/read/28917303/the-evaluation-of-gm6-based-elisa-and-ict-as-diagnostic-methods-on-a-mongolian-farm-with-an-outbreak-of-non-tsetse-transmitted-horse-trypanosomosis
#1
Batdorj Davaasuren, Tovuu Amgalanbaatar, Simon Peter Musinguzi, Keisuke Suganuma, Davaajav Otgonsuren, Ehab Mossaad, Sandagdorj Narantsatsral, Banzragch Battur, Badgar Battsetseg, Xuenan Xuan, Noboru Inoue
Trypanosoma equiperdum, which is the etiological agent of dourine, spreads through sexual intercourse in equines. Dourine (T. equiperdum) has been reported in Mongolia, where it is considered an economically important disease of horses. T. evansi has also been reported in Mongolian domestic animals. The objective of this study was to evaluate the potential application of recombinant T. evansi GM6 (rTeGM6-4r)-based diagnostic methods on a farm with an outbreak of non-tsetse transmitted horse trypanosomosis. Ninety-seven percent homology was found between the amino acid sequences of T...
September 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28904985/cholinergic-activity-and-levodopa-induced-dyskinesia-a-multitracer-molecular-imaging-study
#2
Joachim Brumberg, Sebastian Küsters, Ehab Al-Momani, Giorgio Marotta, Kelly P Cosgrove, Christopher H van Dyck, Ken Herrmann, György A Homola, Gianni Pezzoli, Andreas K Buck, Jens Volkmann, Samuel Samnick, Ioannis U Isaias
OBJECTIVE: To investigate the association between levodopa-induced dyskinesias and striatal cholinergic activity in patients with Parkinson's disease. METHODS: This study included 13 Parkinson's disease patients with peak-of-dose levodopa-induced dyskinesias, 12 nondyskinetic patients, and 12 healthy controls. Participants underwent 5-[(123)I]iodo-3-[2(S)-2-azetidinylmethoxy]pyridine single-photon emission computed tomography, a marker of nicotinic acetylcholine receptors, [(123)I]N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane single-photon emission computed tomography, to measure dopamine reuptake transporter density and 2-[(18)F]fluoro-2-deoxyglucose positron emission tomography to assess regional cerebral metabolic activity...
September 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28900722/molecular-characterization-of-bovine-cryptosporidium-isolated-from-diarrheic-calves-in-the-sudan
#3
Shahinaz Taha, Khitma Elmalik, Berit Bangoura, Matthias Lendner, Ehab Mossaad, Arwid Daugschies
Cryptosporidiosis is a common protozoan infection causing morbidity and mortality in young cattle and may be zoonotically transmitted to humans. So far, there is no data available on the presence of Cryptosporidium spp. in the Sudan. The aim of this study was to isolate, identify, and genotype Cryptosporidium oocysts sampled from diarrheic calves housed at different farms in three different municipalities in Khartoum State (Khartoum, Khartoum North, Omdurman). A total of 149 fecal samples were evaluated microscopically for the presence of Cryptosporidium oocysts using the modified Ziehl-Neelsen staining method and 87 (58...
September 13, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28891839/the-relative-effects-of-dexmedetomidine-and-propofol-on-cerebral-blood-flow-velocity-and-regional-brain-oxygenation-a-randomised-noninferiority-trial
#4
Ehab Farag, Michael Kot, Attila Podolyak, Maged Argalious, Milind Deogaonkar, Edward J Mascha, Zekun Xu, Irene Katzan, Zeyd Ebrahim
BACKGROUND: Dexmedetomidine constricts cerebral blood vessels without a concomitant reduction in cerebral metabolic oxygen consumption. Its safety as a sedative in patients with neurological diseases thus remains uncertain. OBJECTIVE: Our primary objective was to test the hypothesis that dexmedetomidine is noninferior to propofol as regards cerebral blood flow (CBF) velocity and brain oxygenation. DESIGN: Unblinded randomised trial. SETTING: Cleveland Clinic Hospital, Cleveland, from November 2010 to July 2013...
June 19, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28890045/the-renin-angiotensin-system-and-the-brain-new-developments
#5
REVIEW
Ehab Farag, Daniel I Sessler, Zeyd Ebrahim, Andrea Kurz, Joseph Morgan, Sanchit Ahuja, Kamal Maheshwari, D John Doyle
The traditional renin-angiotensin system (RAS) is indispensable system in adjusting sodium homeostasis, body fluid volume, and controlling arterial blood pressure. The key elements are renin splitting inactive angiotensinogen to yield angiotensin (Ang-I). Ang-1 is then changed by angiotensin-1 converting enzyme (ACE) into angiotensin II (Ang-II). Using PubMed, Google Scholar, and other means, we searched the peer-reviewed literature from 1990 to 2013 for articles on newly discovered findings related to the RAS, especially focusing on how the system influences the central nervous system (CNS)...
September 7, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28888224/long-term-patient-reported-outcomes-following-radiation-therapy-for-oropharyngeal-cancer-cross-sectional-assessment-of-a-prospective-symptom-survey-in-patients-%C3%A2-65%C3%A2-years-old
#6
Salman A Eraj, Mona K Jomaa, Crosby D Rock, Abdallah S R Mohamed, Blaine D Smith, Joshua B Smith, Theodora Browne, Luke C Cooksey, Bowman Williams, Brandi Temple, Kathryn E Preston, Jeremy M Aymar, Neil D Gross, Randal S Weber, Amy C Hessel, Renata Ferrarotto, Jack Phan, Erich M Sturgis, Ehab Y Hanna, Steven J Frank, William H Morrison, Ryan P Goepfert, Stephen Y Lai, David I Rosenthal, Tito R Mendoza, Charles S Cleeland, Kate A Hutcheson, Clifton D Fuller, Adam S Garden, G Brandon Gunn
BACKGROUND: Given the potential for older patients to experience exaggerated toxicity and symptoms, this study was performed to characterize patient reported outcomes in older patients following definitive radiation therapy (RT) for oropharyngeal cancer (OPC). METHODS: Cancer-free head and neck cancer survivors (>6 months since treatment completion) were eligible for participation in a questionnaire-based study. Participants completed the MD Anderson Symptom Inventory-Head and Neck module (MDASI-HN)...
September 9, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28882807/atlantic-salmon-endothelial-cells-from-the-heart-were-more-susceptible-than-fibroblasts-from-the-bulbus-arteriosus-to-four-rna-viruses-but-protected-from-two-viruses-by-dsrna-pretreatment
#7
Phuc H Pham, Winnie W L Tong, Ehab Misk, Ginny Jones, John S Lumsden, Niels C Bols
Heart diseases caused by viruses are major causes of Atlantic salmon aquaculture loss. Two Atlantic salmon cardiovascular cell lines, an endothelial cell line (ASHe) from the heart and a fibroblast cell line (BAASf) from the bulbus arteriosus, were evaluated for their response to four fish viruses, CSV, IPNV, VHSV IVa and VHSV IVb, and the innate immune agonist, double-stranded RNA mimic poly IC. All four viruses caused cytopathic effects in ASHe and BAASf. However, ASHe was more susceptible to all four viruses than BAASf...
September 4, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28877597/acute-onset-of-bilateral-lower-extremity-weakness-and-unsteady-gait-in-a-toddler
#8
Feenalie Patel, Ashley Kiefer, Price T Edwards, Diego R Hijano, Ehab Dayyat, Bindiya Bagga
No abstract text is available yet for this article.
September 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28856450/the-incrimination-of-three-trypanosome-species-in-clinically-affected-german-shepherd-dogs-in-sudan
#9
Ehab Mossaad, Rawan A Satti, Abdeen Fadul, Keisuke Suganuma, Bashir Salim, E A Elamin, Simon Peter Musinguzi, Xuenan Xuan, Noboru Inoue
Canine trypanosomosisis (CT) is a common disease caused by tsetse- and non-tsetse-transmitted trypanosomes worldwide. The severity of the disease varies from acute, sub-acute to chronic with non-specific clinical signs. Here, we attempt in a cross-sectional study to assess the current situation of CT and the role of dogs in transmitting trypanosomes to other domesticated animals. The study was carried out during July 2016 on 50 caged German shepherd dogs in Khartoum State to investigate the prevalence of dog trypanosomosis using both serological (CATT/Trypanosoma evansi) and molecular (KIN-PCR, RoTat1...
August 30, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28846773/racioethnic-differences-in-human-posterior-scleral-and-optic-nerve-stump-deformation
#10
COMPARATIVE STUDY
Ehab A Tamimi, Jeffrey D Pyne, Dominic K Muli, Katelyn F Axman, Stephen J Howerton, Matthew R Davis, Christopher A Girkin, Jonathan P Vande Geest
Purpose: The purpose of this study was to quantify the biomechanical response of human posterior ocular tissues from donors of various racioethnic groups to better understand how differences in these properties may play a role in the racioethnic health disparities known to exist in glaucoma. Methods: Sequential digital image correlation (S-DIC) was used to measure the pressure-induced surface deformations of 23 normal human posterior poles from three racioethnic groups: African descent (AD), European descent (ED), and Hispanic ethnicity (HIS)...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28844366/syringomyelia-associated-with-cervical-spondylotic-myelopathy-causing-canal-stenosis-a-rare-association
#11
Dirk Pillich, Ehab El Refaee, Jan-Uwe Mueller, Amr Safwat, Henry W S Schroeder, Joerg Baldauf
BACKGROUND: Although cervical spondylosis is extremely common, only few cases with associated syrinx have been reported. Depending on review of two large data bases, we report this case series. In addition, we evaluated the posterior decompression as the management option in treatment of this rare condition. MATERIALS AND METHODS: Data of all cases with cervical spondylosis and canal stenosis that sought medical advice or needed decompressive laminectomy/laminoplasty between the years 2006 and 2015 were checked in manually...
August 14, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28843220/association-of-c-myc-and-p53-gene-expression-and-polymorphisms-with-hepatitis-c-hcv-chronic-infection-cirrhosis-and-hepatocellular-carcinoma-hcc-stages-in-egypt
#12
Fayed Koutb, Salah Abdel-Rahman, Ehab Hassona, Amany Haggag
The aim of this study is to investigate c-myc and p53 gene expression and polymorphisms in different stages of HCV infection,. Expression levels of c-myc and p53 were evaluated by RT-PCR and polymorphisms were determined by PCR-RFLP in 60 HCV patients classified into chronic infection, cirrhosis and HCC groups along with 30 controls. c-myc gene expression significant increased through the stages as compared to the control level (1.17, 1.82, 3.33 and 0.32, respectively), whereas p53 significantly declined (4,375, 3,842, 525 and 5,498, respectively)...
August 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28831781/a-huge-left-atrial-mass-not-a-myxoma
#13
Thomas Strecker, Petra Rümmele, Timo Seitz, Ehab Nooh
N/A.
2017: Cardiology Journal
https://www.readbyqxmd.com/read/28831220/serotyping-antibiotic-susceptibility-and-virulence-genes-screening-of-escherichia-coli-isolates-obtained-from-diarrheic-buffalo-calves-in-egyptian-farms
#14
Ashraf S Hakim, Shimaa T Omara, Sohier M Syame, Ehab A Fouad
AIM: In Egypt as in many other countries, river water buffalo (Bubalus bubalis) is considered an important source of high-quality milk and meat supply. The objective of this study was to investigate serotypes, virulence genes, and antibiotic resistance determinants profiles of Escherichia coli isolated from buffalo at some places in Egypt; noticibly, this issue was not discussed in the country yet. MATERIALS AND METHODS: A number of 58 rectal samples were collected from diarrheic buffalo calves in different regions in Egypt, and bacteriological investigated for E...
July 2017: Veterinary World
https://www.readbyqxmd.com/read/28804042/four-hand-suction-irrigation-technique-leads-to-gross-total-resection-and-long-term-progression-free-survival-in-fourth-ventricular-ependymoma
#15
Sascha Marx, Ehab El Refaee, Soenke Langner, Henry W S Schroeder
BACKGROUND: Gross total resection is often avoided in posterior fossa ependymoma surgery due to the fear of permanent neurological deficits after operation. However, the extent of resection is a major prognostic factor for progression free and overall survival. The present study evaluates the outcome of posterior fossa ependymoma gross total resection in adult patients using a four-hand suction-irrigation technique at the floor of the fourth ventricle. METHODS: All surgical procedures for posterior fossa ependymomas performed since 2001 in the Department of Neurosurgery, University Medicine Greifswald, were analysed...
August 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28783769/radiation-therapy-managing-gi-tract-complications
#16
Neshan Tabibian, Aisha Umbreen, Ehab Swehli, Anne Boyd, James H Tabibian
Here's how to recognize radiation-related adverse effects so that you can expedite care and help preserve your patient's quality of life.
August 2017: Journal of Family Practice
https://www.readbyqxmd.com/read/28766808/investigation-of-the-regenerative-potential-of-necrotic-mature-teeth-following-different-revascularisation-protocols
#17
Sarah Hossam Fahmy, Ehab El Sayed Hassanien, Mohamed Mokhtar Nagy, Kariem Mostafa El Batouty, Mohamed Mekhemar, Karim Fawzy El Sayed, El Hassan Hassanein, Jörg Wiltfang, Christof Dörfer
This study aimed to assess the revascularisation potential of necrotic mature teeth in a dog model following different protocols. Periapical infection was induced in 54 mature premolars. Teeth were distributed into seven groups: (1) Double-antibiotic-paste/Blood clot, (2) Ciprofloxacin/collagen, (3) Double-antibiotic-paste/Collagen, (4) Modified Tri-antibiotic-paste /collagen, (5) Ciprofloxacin/Gelfoam, (6) Double-antibiotic-paste/Gelfoam, and (7) Modified Triantibiotic- paste/Gelfoam. Positive and negative controls included infected and healthy teeth, respectively, (n = 12 roots/group)...
August 2017: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://www.readbyqxmd.com/read/28763137/cognitive-function-and-patient-reported-memory-problems-after-radiotherapy-for-cancers-at-the-skull-base-a-cross-sectional-survivorship-study-using-the-telephone-interview-for-cognitive-status-and-the-md-anderson-symptom-inventory-head-and-neck-module
#18
Chase C Hansen, Joshua B Smith, Abdallah S R Mohamed, Collin F Mulcahy, Jeffrey S Wefel, Katherine A Hutcheson, Kelsey Chrane, Jack Phan, Steven J Frank, Adam S Garden, Blaine D Smith, Hillary Eichelberger, Carthal Anderson, Colton McCoy, Marina Horiates, Conner Patrick, Sarah Floris, Chloe French, Beth M Beadle, William H Morrison, Shirley Y Su, Carol M Lewis, Michael E Kupferman, Jason M Johnson, Heath D Skinner, Stephen Y Lai, Ehab Y Hanna, David I Rosenthal, Clifton D Fuller, G Brandon Gunn
BACKGROUND: Using patient-reported and objective assessment tools, we sought to quantify cognitive symptoms and objective cognitive dysfunction in patients irradiated for skull base cancer. METHODS: Participants were assessed using the Telephone Interview for Cognitive Status (TICS) and the MD Anderson Symptom Inventory-Head and Neck module (MDASI-HN), with subsequent analysis. RESULTS: Of the 122 participants analyzed, the majority (63%) had no frank detectable cognitive impairment by TICS, with frank impairment in 6%...
August 1, 2017: Head & Neck
https://www.readbyqxmd.com/read/28760039/neuronavigation-and-3d-fluoroscopy-guided-lag-screw-reduction-and-osteosynthesis-for-traumatic-spondylolistheses-of-the-axis-a-path-worth-exploring
#19
Jan-Philip Zeden, Jan-Uwe Müller, Ehab Ahmed Mohamed El Refaee, Henry W S Schroeder, Dirk T Pillich
OBJECTIVE In traumatic spondylolistheses of the axis, there is a marked heterogeneity of the observed injury patterns, with a wide range of the severity-from stable fractures, which can be treated conservatively with very good success, to highly unstable fractures, which should be treated surgically. A number of classification systems have been devised to assess the instability of the injuries and to derive a corresponding therapy recommendation. In particular, the results and recommendations regarding medium-severity cases are still inconclusive...
August 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28759638/influence-of-the-microwave-technology-on-solid-dispersions-of-mefenamic-acid-and-flufenamic-acid
#20
Sultan Alshehri, Faiyaz Shakeel, Mohamed Ibrahim, Ehab Elzayat, Mohammad Altamimi, Gamal Shazly, Kazi Mohsin, Musaed Alkholief, Bader Alsulays, Abdullah Alshetaili, Abdulaziz Alshahrani, Bander Almalki, Fars Alanazi
The present studies were undertaken to develop solvent-free solid dispersions (SDs) for poorly soluble anti-inflammatory drugs mefenamic acid (MA) and flufenamic acid (FFA) in order to enhance their in vitro dissolution rate and in vivo anti-inflammatory effects. The SDs of MA and FFA were prepared using microwaves irradiation (MW) technique. Different carriers such as Pluronic F127® (PL), Eudragit EPO® (EPO), polyethylene glycol 4000 (PEG 4000) and Gelucire 50/13 (GLU) were used for the preparation of SDs...
2017: PloS One
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