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https://www.readbyqxmd.com/read/29680429/repetitive-thought-is-associated-with-both-subjectively-and-objectively-recorded-polysomnographic-indices-of-disrupted-sleep-in-insomnia-disorder
#1
Andrea Galbiati, Enrico Giora, Simone Sarasso, Marco Zucconi, Luigi Ferini-Strambi
BACKGROUND: Repetitive thought is a hallmark of several psychopathological conditions and in particular a perpetuating and maintaining factor in Insomnia Disorder. Accordingly, one of the primary complaints reported by Insomnia patients is the inability to shut-off or control thoughts. Worry and rumination are the two best-known styles of repetitive thought leading to sleep disturbances. The aim of this study was to investigate the relationship of these two cognitive processes on nocturnal sleep indices objectively recorded by polysomnography...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29680423/nocturnal-sleep-architecture-in-idiopathic-hypersomnia-a-systematic-review-and-meta-analysis
#2
David T Plante
BACKGROUND: Current sleep medicine nosology places increased importance on nocturnal polysomnographic sleep recordings in the diagnosis of central nervous system disorders of hypersomnolence, particularly idiopathic hypersomnia (IH). OBJECTIVE: Determine what differences in sleep staging and architecture exist between IH and healthy controls using meta-analysis. METHODS: Systematic review identified relevant studies that included nocturnal polysomnography data for IH and healthy control groups...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29680416/electrocardiographic-variables-in-children-with-syndromic-craniosynostosis-and-primary-snoring-to-mild-obstructive-sleep-apnea-significance-of-identifying-respiratory-arrhythmia-during-sleep
#3
Ellaha Kakar, Linda J A Corel, Robert C Tasker, Robbin de Goederen, Eppo B Wolvius, Irene M J Mathijssen, Koen F M Joosten
BACKGROUND: In the spectrum of children with symptomatic sleep disordered breathing (SDB), some individuals - such as those with upper airway resistance syndrome (UARS) - do not have abnormalities on polysomnography (PSG). In this study we have assessed whether assessment of respiratory arrhythmia (RA) and heart rate variability (HRV) analysis helps in management of children with syndromic craniosynostosis and none-to-mild obstructive sleep apnea (OSA). METHODS: Prospective cohort study in children aged 1-18 years old with syndromic craniosynostosis...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29679174/sleep-abnormalities-in-multiplesystem-atrophy
#4
REVIEW
Valérie Cochen De Cock
PURPOSE OF REVIEW: The purpose of this review was to explore the different sleep disorders associated with MSA, their mechanisms, and their treatments. RECENT FINDINGS: Stridor is a red flag for the diagnosis of MSA. Recent findings show that its presence in early stage of the disease is associated with a reduction in life expectancy. Its management should be fast and adapted. Its treatment with continuous positive airway pressure or tracheostomy is efficacious...
April 20, 2018: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/29675716/disturbances-of-sleep-and-alertness-in-parkinson-s-disease
#5
REVIEW
Aleksandar Videnovic
PURPOSE OF REVIEW: Parkinson's disease (PD) is the second most common neurodegenerative disorder. Sleep dysfunction is one of the most common non-motor manifestations of PD that has gained significant interest over the past two decades due to its impact on the daily lives of PD patients, poorly understood mechanisms, and limited treatment options. In this review, we discuss the most common sleep disorders in PD and present recent investigations that have broadened our understanding of the epidemiology, clinical manifestations, diagnosis, and treatment of disturbed sleep and alertness in PD...
April 19, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29671235/evaluation-of-neurotransmitter-alterations-in-four-distinct-brain-regions-after-rapid-eye-movement-sleep-deprivation-remsd-induced-mania-like-behaviour-in-swiss-albino-mice
#6
Saiful Alom Siddique, Thangavel Tamilselvan, Manikkannan Vishnupriya, Elumalai Balamurugan
A number of neurotransmitter systems have been implicated in contributing to the pathology of mood disorders, including those of dopamine (DA), serotonin (5-HT), norepinephrine (NE) and γ-aminobutyric acid (GABA). Rapid eye movement sleep deprivation (REMSD) alters most of the neurotransmitters, which may have adverse behavioural changes and other health consequences like mania and other psychiatric disorders. The exact role of REMSD altered neurotransmitter levels and the manner in which emerging consequences lead to mania-like behaviour is poorly understood...
April 18, 2018: Neurochemical Research
https://www.readbyqxmd.com/read/29669910/the-clinical-relevance-of-cognitive-impairment-in-rem-sleep-behavior-disorder
#7
EDITORIAL
Dario Arnaldi, Flavio Nobili
No abstract text is available yet for this article.
April 18, 2018: Neurology
https://www.readbyqxmd.com/read/29669906/cortical-and-subcortical-gray-matter-bases-of-cognitive-deficits-in-rem-sleep-behavior-disorder
#8
Shady Rahayel, Ronald B Postuma, Jacques Montplaisir, Daphné Génier Marchand, Frédérique Escudier, Malo Gaubert, Pierre-Alexandre Bourgouin, Julie Carrier, Oury Monchi, Sven Joubert, Frédéric Blanc, Jean-François Gagnon
OBJECTIVE: To investigate cortical and subcortical gray matter abnormalities underlying cognitive impairment in patients with REM sleep behavior disorder (RBD) with or without mild cognitive impairment (MCI). METHODS: Fifty-two patients with RBD, including 17 patients with MCI, were recruited and compared to 41 controls. All participants underwent extensive clinical assessments, neuropsychological examination, and 3-tesla MRI acquisition of T1 anatomical images...
April 18, 2018: Neurology
https://www.readbyqxmd.com/read/29667182/breathing-regulation-and-blood-gas-homeostasis-after-near-complete-lesions-of-the-retrotrapezoid-nucleus-in-adult-rats
#9
George M P R Souza, Roy Kanbar, Daniel S Stornetta, Stephen B G Abbott, Ruth L Stornetta, Patrice G Guyenet
The retrotrapezoid nucleus (RTN) is one of several CNS nuclei that contribute, in various capacities (e.g. CO2 detection, neuronal modulation) to the central respiratory chemoreflex (CRC). Here we test how important the RTN is to PCO2 homeostasis and breathing during sleep or wake. RTN Nmb positive neurons were killed with targeted microinjections of substance-P-saporin conjugate in adult rats. Under normoxia, rats with large RTN lesions (92 ± 4 % cell loss) had normal blood pressure (BP) and arterial pH but were hypoxic (-8 mmHg PaO2 ) and hypercapnic (+10 mmHg PaCO2 )...
April 18, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29665124/how-does-dementia-with-lewy-bodies-start-prodromal-cognitive-changes-in-rem-sleep-behavior-disorder
#10
Daphné Génier Marchand, Ronald B Postuma, Frédérique Escudier, Jessie De Roy, Amélie Pelletier, Jacques Montplaisir, Jean-François Gagnon
Objective We describe the progression of cognitive decline and identify the predictive values of cognitive tests in three groups of REM sleep behavior disorder (RBD) patients classified at their last follow-up as having Parkinson's disease (PD), dementia with Lewy bodies (DLB), or still-idiopathic. Methods Patients (n=109) underwent polysomnographic, neurological, and neuropsychological assessments. We used linear mixed-model analyses to compare the progression of cognitive test performance between the three groups over a three-year prodromal period, and performed linear regressions for a six-year prodromal period...
April 17, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29664048/effect-of-rapid-eye-movement-sleep-behavior-disorder-on-obstructive-sleep-apnea-severity-and-cognition-of-parkinson-s-disease-patients
#11
Jun-Ying Huang, Jin-Ru Zhang, Yun Shen, Hui-Jun Zhang, Yu-Lan Cao, Cheng-Jie Mao, Ya-Ping Yang, Jing Chen, Chun-Feng Liu, Jie Li
Background: Rapid eye movement (REM) sleep behavior disorder (RBD) and obstructive sleep apnea (OSA) are the most common sleep disorders in Parkinson's disease (PD). The aim of this study was to identify whether RBD could alleviate OSA severity in PD patients and its effect on cognitive impairment. Methods: From February 2014 to May 2017, we recruited 174 PD patients from the Second Affiliated Hospital of Soochow University, all of whom underwent polysomnography (PSG)...
April 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29644271/venlafaxine-induced-rem-sleep-behavioral-disorder-presenting-as-two-fractures
#12
R Ryan Williams, Gustavo Sandigo
Rapid eye movement (REM) sleep behavioral disorder is characterized by the absence of muscular atonia during REM sleep. In this disorder, patients can violently act out their dreams, placing them at risk for traumatic fractures during these episodes. REM sleep behavioral disorder (RBD) can be a sign of future neurodegenerative disease and has also been found to be a side effect of certain psychiatric medications. We present a case of venlafaxine-induced RBD in a 55 year old female who presented with a 13 year history of intermittent parasomnia and dream enactment in addition to a recent history of two fractures requiring intervention...
October 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29628334/consolidative-mechanisms-of-emotional-processing-in-rem-sleep-and-ptsd
#13
REVIEW
Anthony L A Murkar, Joseph De Koninck
Research suggests sleep plays a role in the consolidation of recently acquired memories for long-term storage. rapid eye movement (REM) sleep has been shown to play a complex role in emotional-memory processing, and may be involved in subsequent waking-day emotional reactivity and amygdala responsivity. Interaction of the hippocampus and basolateral amygdala with the medial-prefrontal cortex is associated with sleep-dependent learning and emotional memory processing. REM is also implicated in post-traumatic stress disorder (PTSD), which is characterized by sleep disturbance, heightened reactivity to fearful stimuli, and nightmares...
March 15, 2018: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29624773/sleep-disorders-in-spinocerebellar-ataxia-type-10
#14
Ester London, Carlos H F Camargo, Alessandra Zanatta, Ana C Crippa, Salmo Raskin, Renato P Munhoz, Tetsuo Ashizawa, Hélio A G Teive
As sleep disturbances have been reported in spinocerebellar ataxias (SCAs), including types SCA1, SCA2, SCA3, SCA6 and SCA13, identification and management of these disturbances can help minimise their impact on SCA patients' overall body functions and quality of life. To our knowledge, there are no studies that investigate sleep disturbances in SCA10. Therefore, the aim of this study was to assess sleep disturbances in patients with SCA10. Twenty-three SCA10 patients and 23 healthy controls were recruited...
April 6, 2018: Journal of Sleep Research
https://www.readbyqxmd.com/read/29618627/baseline-symptoms-and-basal-forebrain-volume-predict-future-psychosis-in-early-parkinson-disease
#15
Matthew J Barrett, Jamie C Blair, Scott A Sperling, Mark E Smolkin, T Jason Druzgal
OBJECTIVE: Determining baseline predictors of future psychosis in Parkinson disease (PD) may identify those at risk for more rapidly progressive disease, i.e., a more malignant PD subtype. METHODS: This cohort study evaluated 423 patients with newly diagnosed PD collected as part of the Parkinson's Progression Markers Initiative. Psychotic symptoms were assessed with the Movement Disorders Society-Unified Parkinson Disease Rating Scale item 1.2, which assesses hallucinations and psychosis over the past week...
April 4, 2018: Neurology
https://www.readbyqxmd.com/read/29597138/rapid-eye-movement-sleep-behavior-disorder-or-epileptic-seizure-during-sleep-a-video-analysis-of-motor-events
#16
Vi-Huong Nguyen-Michel, Ovidio Solano, Smaranda Leu-Semenescu, Aurélie Pierre-Justin, Ana Gales, Vincent Navarro, Michel Baulac, Claude Adam, Sophie Dupont, Isabelle Arnulf
PURPOSE: To compare the motor semiology of sleep behavior disorder (RBD) during rapid eye movement (REM) with epileptic seizures in non-REM and REM sleep. METHODS: We analyzed the types and frequency of motor events from videos of patients with RBD (n = 15, mean age 64.8 years, 179 motor episodes) and patients with epilepsy (n = 15, mean age 34.4 years, 87 sleep-related epileptic seizures including 34 during REM sleep). RESULTS: Patients with sleep-related epileptic seizures more often woke up abruptly (28% vs...
March 21, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29578489/rem-sleep-behavior-disorder-and-alzheimer-s-disease-definitely-no-relationship
#17
Andrea Galbiati, Giulia Carli, Michael Hensley, Luigi Ferini-Strambi
Rapid eye movement (REM) sleep behavior disorder (RBD) is a REM sleep parasomnia characterized by the loss of the typical muscular atonia present during healthy REM sleep. RBD can occur in the absence of other neurological conditions or in association with a neurodegenerative disorder. It is now well established that RBD is a strong predictor of neurodegeneration, in particular synucleinopathies, such as Parkinson's disease, Lewy body dementia (LBD), or multiple system atrophy. However, some longitudinal studies report that a minority of patients develop either overlapping form of dementia or Alzheimer disease's (AD)...
March 23, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29576439/lrrk2-protective-haplotype-and-full-sequencing-study-in-rem-sleep-behavior-disorder
#18
Bouchra Ouled Amar Bencheikh, Jennifer A Ruskey, Isabelle Arnulf, Yves Dauvilliers, Christelle Charley Monaca, Valérie Cochen De Cock, Jean-François Gagnon, Dan Spiegelman, Michele T M Hu, Birgit Högl, Ambra Stefani, Luigi Ferini-Strambi, Giuseppe Plazzi, Elena Antelmi, Peter Young, Anna Heidbreder, Brit Mollenhauer, Friederike Sixel-Döring, Claudia Trenkwalder, Wolfgang Oertel, Jacques Y Montplaisir, Ronald B Postuma, Guy A Rouleau, Ziv Gan-Or
BACKGROUND: Individuals with rapid eye movement (REM)-sleep behavior disorder (RBD) are likely to progress to synucleinopathies, mainly Parkinson's disease (PD), dementia with Lewy-bodies (DLB) and multiple system atrophy (MSA). The genetics of RBD only partially overlaps with PD and DLB, and the role of LRRK2 variants in risk for RBD is still not clear. METHODS: The full coding sequence, exon-intron boundaries and 5' and 3' untranslated regions of LRRK2 were sequenced using targeted next-generation sequencing...
March 21, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29569570/behavioral-and-psychological-symptoms-in-lewy-body-disease-a-review
#19
Lucie Jurek, Mathieu Herrmann, Mathilde Bonze, Sophie Brunet, Catherine Padovan, Jean-Michel Dorey
Dementia with Lewy bodies (DLB) is a common neurodegenerative disease, second in terms of prevalence after Alzheimer's disease (AD). DLB may be suspected according to three core features which are cognitive and motor fluctuations, early visual hallucinations and parkinsonism; and more recently, according to the new criteria, REM sleep behavior disorder (RBD). Behavorial and psychological symptoms associated with DLB are more frequent, more severe and appear earlier than those found in other neurodegenerative diseases...
March 1, 2018: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/29560834/comparison-of-structural-connectivity-in-parkinson-s-disease-with-depressive-symptoms-versus-non-depressed-a-diffusion-mri-connectometry-study
#20
Mina Ansari, Sahand Adib Moradi, Farzaneh Ghazi Sherbaf, Abozar Hedayatnia, Mohammad Hadi Aarabi
OBJECTIVE: Research on psychobiological markers of Parkinson's disease (PD) remains a hot topic. Non-motor symptoms such as depression and REM sleep behavior disorder (RBD) each attribute to a particular neurodegenerative cluster in PD, and might enlighten the way for early prediction/detection of PD. The neuropathology of mood disturbances remains unclear. In fact, a few studies have investigated depression using diffusion magnetic resonance imaging (diffusion MRI). METHOD: Diffusion MRI of PD patients without comorbid RBD was used to assess whether microstructural abnormalities are detectable in the brain of 40 PD patients with depression compared to 19 patients without depression...
March 21, 2018: International Psychogeriatrics
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