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Oral Bone Graft

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https://www.readbyqxmd.com/read/29658528/gait-changes-in-patients-after-reconstruction-of-facial-bones-with-fibula-and-iliac-crest-free-vascularized-flaps
#1
Małgorzata Syczewska, Romuald Krajewski, Monika Kirwil, Ewa Szczerbik, Małgorzata Kalinowska
PURPOSE: Patients with malignant tumours of the oral cavity require its surgical removal and reconstruction of the bone and soft tissues. The grafts are obtained either from leg (fibula) or pelvis (iliac crest). The removal of grafts from the locomotor apparatus can impair the gait. The aim of this study was to find out how the localization of donor site influences the gait pattern. METHODS: Results obtained for 30 patients were analyzed (16 fibula graft, 14 iliac crest graft)...
2018: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29656899/long-term-outcome-of-patients-with-or-without-osseointegrated-implants-after-resection-of-mandibular-ameloblastoma-and-reconstruction-with-vascularized-bone-graft-functional-assessment-and-quality-of-life
#2
Marco Pappalardo, Chung-Kan Tsao, Man Lung Tsang, Jie Zheng, Yang-Ming Chang, Chi-Ying Tsai
BACKGROUND: The optimal management after the resection of mandibular ameloblastoma has been very challenging to surgeons. The aim of this study is to evaluate the functional, aesthetic, and quality of life outcomes of patients who had a segmental mandibular resection and immediate reconstruction with or without osseointegrated implants. METHOD: Patients' demographics, tumor characteristics, treatment, and complications were retrieved. Patients were divided into two groups: dental rehabilitated vs...
March 28, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29651386/tissue-engineering-in-maxillary-bone-defects
#3
Azizollah Khodakaram-Tafti, Davood Mehrabani, Hanieh Shaterzadeh-Yazdi, Barbad Zamiri, Mahsa Omidi
BACKGROUND: Restoration of craniofacial bone defects has been a concern for oral and maxillofacial surgeons. In this study, the healing effect of fibrin glue scaffold was compared with autologous bone graft in mandibular defects of rabbit. METHODS: Bilateral unicortical osteotomy was performed in the diastema region of 10 male Dutch rabbits. The subjects were randomly divided into 2 equal groups. The mandibular defect on the right side was treated with fibrin glue scaffold and the defect on the left side with autologous bone graft provided from iliac crest...
January 2018: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/29644089/heterotopic-bone-formation-in-the-musculus-latissimus-dorsi-of-sheep-using-%C3%AE-tricalcium-phosphate-scaffolds-evaluation-of-different-seeding-techniques
#4
Simon Spalthoff, Rüdiger Zimmerer, Jan Dittmann, Horst Kokemüller, Marco Tiede, Laura Flohr, Philippe Korn, Nils-Claudius Gellrich, Philipp Jehn
Osseous reconstruction of large bone defects remains a challenge in oral and maxillofacial surgery. In addition to autogenous bone grafts, which despite potential donor-site mobility still represent the gold standard in reconstructive surgery, many studies have investigated less invasive alternatives such as in vitro cultivation techniques. This study compared different types of seeding techniques on pure β-tricalcium phosphate scaffolds in terms of bone formation and ceramic resorption in vivo . Cylindrical scaffolds loaded with autologous cancellous bone, venous blood, bone marrow aspirate concentrate or extracorporeal in vitro cultivated bone marrow stromal cells were cultured in sheep on a perforator vessel of the musculus latissimus dorsi over a 6-month period...
March 2018: Regenerative Biomaterials
https://www.readbyqxmd.com/read/29606562/evaluation-of-postoperative-changes-in-vascularized-iliac-bone-grafts-used-for-mandibular-reconstruction
#5
T Noguchi, S Sarukawa, Y Tsuchiya, N Okada, J Hayasaka, K Sasaguri, H Nishino, Y Jinbu, Y Mori
Vascularized iliac bone grafts are used for mandibular reconstruction, but the factors affecting graft maintenance are unknown. This study explored the postsurgical changes in vascularized iliac bone grafts in patients who had undergone mandibular reconstruction after segmental resection. The study involved 24 patients (16 men and eight women) with oral tumours or osteoradionecrosis. Thirteen patients required bare bone grafting (BBG) and 11 patients required reconstruction with soft tissue coverage (six with a skin paddle and five with direct closure)...
March 29, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29600207/treating-a-recalcitrant-non-union-of-the-radius-using-autogenous-bone-equine-bone-paste-equine-demineralized-bone-matrix-platelet-rich-plasma-and-bone-marrow-aspirate-a-case-report
#6
Ferdinando Da Rin De Lorenzo
Introduction: Non-unions at forearms are usually challenging and difficult to treat. If additionally, an infection is present, reconstructive surgery should be planned only after full debridement, antibiotic treatment, and confirmation, based on clinical observation and laboratory tests that the infection has subsided. Bone grafting may be required for reconstruction. The use of autogenous bone calls for a second surgical site with an increased risk of morbidity. Using bone substitutes may reduce the need for autogenous bone...
November 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29590226/spontaneous-correction-of-accentuated-retraction-of-maxillary-central-incisors-after-autogenous-graft-in-midline-mesialization-and-lingual-torque-of-incisor-roots
#7
Matheus Melo Pithon
In the present clinical case, the authors report the orthodontic treatment of an adult patient with Class II malocclusion with periodontal disease and extensive bone destruction in the anterior region of the median palatine suture. Before orthodontic treatment, the patient presented precarious oral health. The treatment proposed for the case was insertion of an autogenous graft and subsequent orthodontic movement of the teeth to the area of the graft. The results obtained were correction of the malocclusion with significant improvement in gingival retraction and smile esthetics...
March 28, 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29561484/the-modified-socket-shield-technique
#8
Chang-Hun Han, Kwang-Bum Park, Francesco Guido Mangano
OBJECTIVE: In the anterior regions, the resorption of the buccal bone after tooth extraction leads to a contraction of the overlying soft tissues, resulting in an esthetic problem, particularly with immediate implant placement. In the socket shield technique, the buccal root section of the tooth is maintained, to preserve the buccal bone for immediate implant placement. The aim of this prospective study was to investigate the survival, stability, and complication rates of implants placed using a "modified" socket shield technique...
March 20, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29535967/primary-sinonasal-mucosal-melanoma-simulated-as-cystic-lesions-a-case-report
#9
Sung-Ho Shin, Hyun Seok, Seong-Gon Kim, Seong-Doo Hong
Sinonasal mucosal melanoma (SNMM) in the maxillary sinus is a rare disease condition. Compared to oral mucosal melanoma, SNMM has a bulky, exophytic, and polypoid appearance, is weakly pigmented, and associated with unspecific symptoms. Due to these features, SNMM in the maxillary sinus has been misdiagnosed as nasal polyps and chronic sinusitis. In this case report, we described SNMM occurring in the right maxillary sinus simulated as a cystic or benign lesion. Cortical bone thinning and expansion were observed around the mass...
February 2018: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/29511796/pharmacokinetics-of-intravenous-mycophenolate-mofetil-in-allogeneic-hematopoietic-stem-cell-transplanted-japanese-patients
#10
Keiji Kurata, Kimikazu Yakushijin, Atsuo Okamura, Motohiro Yamamori, Hiroya Ichikawa, Rina Sakai, Yu Mizutani, Seiji Kakiuchi, Yoshiharu Miyata, Akihito Kitao, Shinichiro Kawamoto, Hiroshi Matsuoka, Tohru Murayama, Hironobu Minami
PURPOSE: Mycophenolate mofetil (MMF) is increasingly used among Japanese patients undergoing allogeneic hematopoietic stem cell transplantation (allo-SCT). Because pharmacokinetic data for MMF in the Asian population are limited, we conducted this investigation. METHODS: Intravenous MMF (1000 mg/dose) was administered to 10 patients along with cyclosporine or tacrolimus for 10 days after allo-SCT; it was administered every 8 h in peripheral blood stem cell- and bone marrow-transplanted patients, and every 12 h in cord blood-transplanted patients...
March 6, 2018: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/29462060/iliac-crest-bone-graft-for-minimally-invasive-transforaminal-lumbar-interbody-fusion-a-prospective-analysis-of-inpatient-pain-narcotics-consumption-and-costs
#11
Brittany E Haws, Benjamin Khechen, Ankur S Narain, Fady Y Hijji, Kaitlyn L Cardinal, Jordan A Guntin, Kern Singh
STUDY DESIGN: Retrospective Analysis OBJECTIVE.: The aim of this study was to determine whether an association between increased acute pain, postoperative time, and direct hospital costs exists between the use of iliac crest bone grafting (ICBG) and bone morphogenic protein (BMP)-2 following a primary, single-level minimally invasive transforaminal lumbar interbody fusion (MIS TLIF). SUMMARY OF BACKGROUND DATA: ICBG has been associated with enhanced fusion rates...
February 16, 2018: Spine
https://www.readbyqxmd.com/read/29460516/clinical-applications-of-natural-bone-morphoproteins-in-dentistry-a-narrative-review
#12
L Ottria, A Palmieri, M Andreasi Bassi, D Lauritano, V Candotto, A Tagliabue, L Tettamanti
The need to restore bone loss in maxilla and mandible has led to find natural bone substitutes, such as fresh autogenous bone grafts. Fresh autogenous bone grafts (FABGs) have a remarkable capacity to induce new bone formation, a phenomenon called ‘osteoinduction.’ FABGs are useful in craniomaxillofacial and oral applications to restore bone deficiencies. The isolation of those proteins believed to be responsible for the osteoinductive activity of FABGs, namely Natural Bone Morphogenetic Proteins (NBMPs), led to a new era in bone regeneration...
January 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29446987/dexmedetomidine-decreases-postoperative-pain-and-narcotic-use-in-children-undergoing-alveolar-bone-graft-surgery
#13
Mariela M Lopez, Derrick Zech, Judith L Linton, Steven J Blackwell
OBJECTIVE: Dexmedetomidine is a parenteral agent that combines the benefits of cooperative sedation, anxiolysis, and analgesia without the risks of respiratory depression. Off-label use has been reported in children. We have introduced dexmedetomidine for use in patients having undergone alveolar bone graft (ABG). The objective is to demonstrate the value and safety of postoperative dexmedetomidine infusion in a non-ICU setting following ABG. DESIGN: A retrospective review was performed on patients who underwent ABG by the senior author...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29438204/effects-of-hyaluronic-acid-and-hydroxyapatite-beta-tricalcium-phosphate-in-combination-on-bone-regeneration-of-a-critical-size-defect-in-an-experimental-model
#14
Nurettin Diker, Serap Gulsever, Taner Koroglu, Eda Yilmaz Akcay, Yener Oguz
Hyaluronic acid (HyA) is an outstanding new product in the field of oral and maxillofacial surgery. The aim of this study was to evaluate the effects of HyA on bone regeneration in critical-size calvarial defects. Twenty-four female Sprague-Dawley rats were used in the present study. In each rat, 4 critical-size defects received different treatments: no treatment (control); HyA; Graft; and HyA + Graft combination. New bone formation, defect closure, inflammation, vascular proliferation, immature bone formation, mature bone formation, and bone marrow existence were investigated based on histological findings...
February 12, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29420674/histomorphometric-study-of-new-bone-formation-comparing-defect-healing-with-three-bone-grafting-materials-the-effect-of-osteoporosis-on-graft-consolidation
#15
Qiao Zhang, Dai Jing, Yufeng Zhang, Richard J Miron
PURPOSE: Bone grafting materials are frequently utilized in oral surgery and periodontology to fill bone defects and augment lost or missing bone. The purpose of this study was to compare new bone formation in bone defects created in both normal and osteoporotic animals loaded with three types of bone grafts from different origins. MATERIALS AND METHODS: Forty-eight female Wistar rats were equally divided into control normal and ovariectomized animals. Bilateral 2...
February 8, 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29417782/-posterior-debridement-interbody-fusion-internal-fixation-for-treatment-of-lumbar-discitis
#16
Lin Chen, Jun Cheng, Bo Li, Fang-Biao Zhan, You Zhang, Shi-Long Feng
OBJECTIVE: To evaluate the clinical effects of posterior debridement, interbody fusion with internal fixation in the treatment of lumbar discitis. METHODS: The clinical data of 13 patients with lumbar discitis treated from January 2005 to June 2012 was retrospectively analyzed. There were 9 males and 4 females, aged from 31 to 68 years old with an average of 56 years old. There were 2 cases on L3, 4, 4 cases on L4, 5, and 7 cases on L5S1. Two cases complicated with diabetes, 4 cases with hypertension, and 1 case with obsolete pulmonary tuberculosis...
May 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29398863/comprehensive-rehabilitation-using-dental-implants-in-generalized-aggressive-periodontitis
#17
Asha Ramesh, Sheethalan Ravi, Gurumoorthy Kaarthikeyan
Generalized aggressive periodontitis (GAP) is a debilitating form of the disease and it results in deteriorating effects on the esthetic and functional aspects of the oral cavity. This case report describes the comprehensive rehabilitation of GAP patient using dental implants. The treatment planning involved thorough scaling and root planning (SRP) with oral hygiene instructions. The patient was motivated to adhere to a strict oral hygiene regimen following which periodontal flap surgery employing guided tissue regeneration and bone grafts was performed...
March 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29386818/efficacy-of-decalcified-freeze-dried-bone-allograft-in-the-regeneration-of-small-osseous-defect-a-comparative-study
#18
Yashmi Jaiswal, Sanjeev Kumar, Vijay Mishra, Puneet Bansal, Kumar Rakshak Anand, Sukumar Singh
Aim: To access the efficacy of decalcified freeze-dried bone allograft (DFDBA) in the regeneration of bone following small osseous defect in minor oral surgery. Objectives: To evaluate the ability of DFDBA to enhance the rate of wound healing and assess radiographic bone density, pain, and infection preoperatively and postoperatively. Materials and Methods: Twenty patients with cysts were assessed. Ten patients were filled with DFDBA (Group 1) and ten without bone graft (Group 2), respectively...
July 2017: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/29384973/patient-and-parent-reported-outcome-measures-in-cleft-lip-and-palate-patients-before-and-after-secondary-alveolar-bone-grafting
#19
Chun-Shin Chang, Christopher Glenn Wallace, Yen-Chang Hsiao, Ting-Chen Lu, Sue-Huei Chen, Fuan-Chiang Chan, Philip Kuo-Ting Chen, Jyh-Ping Chen, Chee-Jen Chang, M Samuel Noordhoff
European and Northern American healthcare authorities increasingly encourage the use of Patient Reported Outcome Measures (PROMs) that complement clinical and laboratory assessments to help holistically evaluate reconstructive outcomes. This is the first study to evaluate PROMs in cleft lip/palate patients who have, or have not, undergone secondary alveolar bone grafting (SABG).A PROMs study was conducted; 40 consecutive consenting cleft lip/palate children between 8 and 14 years old were included. Twenty patients did, and 20 patients did not, have SABG...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29381614/bone-conditioned-medium-obtained-from-calvaria-mandible-and-tibia-cause-an-equivalent-tgf-%C3%AE-1-response-in-vitro
#20
Babak Hatami Kia, João Rui Galvão Mendes, Heinz-Dieter Müller, Patrick Heimel, Reinhard Gruber
Bones with different embryological origin and mode of ossification are supposed to vary in their capacity for supporting graft consolidation. The aim of the current pilot study was to assess the TGF-β1 activity of bone chips obtained from distinct anatomic locations. Conditioned medium was prepared from bone chips harvested from pig calvaria, mandible, and tibia. Human oral fibroblasts were exposed to bone-conditioned medium (BCM) followed by reverse transcriptase polymerase chain reaction of the TGF-β1 target genes...
January 19, 2018: Journal of Craniofacial Surgery
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