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https://www.readbyqxmd.com/read/27931300/clinical-and-etiologic-evaluation-of-the-children-with-chronic-urticaria
#1
Dilek Azkur, Ersoy Civelek, Mge Toyran, Emine Dibek Msrlolu, Mustafa Erkoolu, Ayenur Kaya, Emine Vezir, Tayfur Gini, Ayegl Akan, Can Naci Kocaba
BACKGROUND: Chronic urticaria (CU) is a skin disorder defined as daily or almost daily exhibition of pruritic and transient wheals that last for 6 weeks. CU is divided into two subtypes: chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU). OBJECTIVES: To evaluate the clinical features, possible causes, associated findings, and laboratory results of different subtypes of CU in children according to a new classification. METHODS: In this study, we evaluated the clinical features, laboratory investigations, and provocation tests of children with different subtypes of CU according to a new classification...
November 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27927932/ethical-clinical-translation-of-stem-cell-interventions-for-neurologic-disease
#2
David J Cote, Annelien L Bredenoord, Timothy R Smith, Mario Ammirati, Jannick Brennum, Ivar Mendez, Ahmed S Ammar, Naci Balak, Gene Bolles, Ignatius Ngene Esene, Tiit Mathiesen, Marike L Broekman
The application of stem cell transplants in clinical practice has increased in frequency in recent years. Many of the stem cell transplants in neurologic diseases, including stroke, Parkinson disease, spinal cord injury, and demyelinating diseases, are unproven-they have not been tested in prospective, controlled clinical trials and have not become accepted therapies. Stem cell transplant procedures currently being carried out have therapeutic aims, but are frequently experimental and unregulated, and could potentially put patients at risk...
December 7, 2016: Neurology
https://www.readbyqxmd.com/read/27879229/the-incidence-of-ototoxicity-in-patients-using-iron-chelators
#3
Serhan Derin, Fatih Mehmet Azık, Yaşar Topal, Hatice Topal, Volkan Karakuş, Petek Uzay Çetinkaya, Murat Şahan, Tansel Erdem Azık, Can Naci Kocabaş
OBJECTIVE: In this study, we aimed to detect the incidences of ototoxicity in patients with hemoglobinopathies taking deferoxamine (DFO), deferiprone, and deferasirox using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) scale to obtain more objective data. MATERIALS AND METHODS: Fifty-five transfusion-dependent patients were evaluated in this study. The NCI CTCAE scale was used to assess ototoxicity levels. The average ferritin and hemoglobin levels, the type of iron chelator, and the duration of therapy of all the patients were recorded...
November 23, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27858509/review-of-seasonal-influenza-in-canada-burden-of-disease-and-the-cost-effectiveness-of-quadrivalent-inactivated-influenza-vaccines
#4
Edward W Thommes, Morgan Kruse, Michele Kohli, Rohita Sharma, Stephen G Noorduyn
In the 2015/16 influenza season, the Canadian National Advisory Committee on Immunization (NACI) recommended vaccination with quadrivalent inactivated influenza vaccine (QIV) for infants aged 6-23 months and trivalent inactivated influenza vaccines (TIVs) or QIVs in adults. The objective of this review (GSK study identifier: HO-13-14054) is to examine the epidemiology and disease burden of influenza in Canada and the economic benefits of vaccination. To inform this review, we performed a systematic literature search of relevant Canadian literature and National surveillance data...
November 18, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27857302/four-core-optical-fiber-as-a-calorimetric-gauge
#5
Sema Güvenç, Belkıs Gökbulut, Gülşen Kösoğlu, Heba Yüksel, Mehmet Naci Inci
A four-core optical fiber is demonstrated as a calorimetric gauge for investigation of one-dimensional heat transfer measurements. Transient heat pulses from a Nd:YAG laser of 600 ms duration with a repetition rate of the order of 10 s are delivered onto the cleaved distal end face of the four-core fiber, aiming at one of the single cores only, which cause an optical path length difference between four guiding cores due to the temperature-induced change in the index of refraction and physical length of the targeted fiber core of concern...
November 10, 2016: Applied Optics
https://www.readbyqxmd.com/read/27814648/mapping-preserved-real-world-cognition-in-severely-brain-injured-patients
#6
Leah Sinai, Adrian M Owen, Lorina Naci
Decoding the contents of consciousness from brain activity is one of most challenging frontiers of cognitive neuroscience. The ability to interpret mental content without recourse to behavior is most relevant for understanding patients who may be demonstrably conscious, but entirely unable to speak or move willfully in any way, precluding any systematic investigation of their conscious experience. Until recently, patient studies have used structured instructions to elicit willful modulation of brain activity according to command...
January 1, 2017: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/27774970/massive-pulmonary-embolism-and-a-cardiac-mass-thrombus-or-metastasis
#7
Murat Gül, Naci Babat, Fatih Mehmet Uçar, Mehmet Serdar Kuyumcu, Özcan Özeke
Cardiac mass can be described as an abnormal structure within or directly contiguous to the heart. Tumors and thrombi are the most common types of cardiac masses. Intracardiac thrombi have been encountered in various clinical settings and can result in severe morbidity and mortality due to embolic events. Cardiac neoplasms are extremely rare, and are usually metastatic tumors. The major primary malignancies associated with cardiac metastases include cancers of the lung, breast, stomach, and liver, and lymphoma, leukemia, and melanoma...
October 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/27601459/communication-of-treatment-rankings-obtained-from-network-meta-analysis-using-data-visualization
#8
Huseyin Naci
No abstract text is available yet for this article.
September 2016: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/27543730/the-etiology-and-clinical-features-of-anaphylaxis-in-a-developing-country-a-nationwide-survey-in-turkey
#9
Ersoy Civelek, Mustafa Erkoçoğlu, Ayşegül Akan, Celal Özcan, Ayşenur Kaya, Emine Vezir, Tayfur Giniş, Müge Toyran, Mahmut Tokaç, Can Naci Kocabaş
BACKGROUND: Despite the increasing frequency of anaphylaxis, there is inadequate information on the etiology and clinical features in various countries, regions and age groups, especially in developing countries. OBJECTIVE: Our aim is to assess the etiology and clinical findings of anaphylaxis in Turkey. Gathering reliable data about the etiology and clinical findings of anaphylaxis in the general population will decrease the related morbidity and mortality. METHOD: We obtained the names and phone numbers of individuals who had been prescribed an epinephrine auto-injector with a diagnosis of anaphylaxis from ministry of health...
August 16, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27515329/cost-implications-of-using-different-ecg%C3%A2-criteria-for-screening-young%C3%A2-athletes%C3%A2-in-the-united-kingdom
#10
Harshil Dhutia, Aneil Malhotra, Vincent Gabus, Ahmed Merghani, Gherardo Finocchiaro, Lynne Millar, Rajay Narain, Michael Papadakis, Huseyin Naci, Maite Tome, Sanjay Sharma
BACKGROUND: High false-positive rates and cost of additional investigations are an obstacle to electrocardiographic (ECG) screening of young athletes for cardiac disease. However, ECG screening costs have never been systematically assessed in a large cohort of athletes. OBJECTIVE: This study investigated the costs of ECG screening in athletes according to the 2010 European Society of Cardiology (ESC) recommendations and the Seattle and refined interpretation criteria...
August 16, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27512351/prevalence-of-skin-disorders-in-primary-and-secondary-school-age-children-in-canakkale-turkey-a-community-based-survey
#11
Aysegul Uludağ, Sevilay Oguz Kılıc, Selda Isık, Yusuf Haydar Ertekin, Murat Tekin, Sibel Cevizci, Zerrin Ogretmen, Naci Topaloglu, Erkan Melih Sahin, Birol Cıbık
INTRODUCTION: Skin lesions may be of dermatological importance, affect appearance, and cause problems communicating with peers and may be especially more significant in childhood. AIM: Information on the prevalence of pediatric dermatoses in Western Turkey. This study was aimed to define the existing data. MATERIAL AND METHODS: A cross-sectional study was conducted in Canakkale, Turkey, in September-December 2013. It involved 1,957 students from five randomly selected primary and secondary schools...
June 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/27465247/exenatide-alters-gene-expression-of-neural-cell-adhesion-molecule-ncam-intercellular-cell-adhesion-molecule-icam-and-vascular-cell-adhesion-molecule-vcam-in-the-hippocampus-of-type-2-diabetic-model-mice
#12
Esen Gumuslu, Naci Cine, Merve Ertan Gökbayrak, Oguz Mutlu, Ipek Komsuoglu Celikyurt, Guner Ulak
BACKGROUND Glucagon-like peptide-1 (GLP-1), a potent and selective agonist for the GLP-1 receptor, ameliorates the symptoms of diabetes through stimulation of insulin secretion. Exenatide is a potent and selective agonist for the GLP-1 receptor. Cell adhesion molecules are members of the immunoglobulin superfamily and are involved in synaptic rearrangements in the mature brain. MATERIAL AND METHODS The present study demonstrated the effects of exenatide treatment (0.1 µg/kg, subcutaneously, twice daily for 2 weeks) on the gene expression levels of cell adhesion molecules, neural cell adhesion molecule (NCAM), intercellular cell adhesion molecule (ICAM), and vascular cell adhesion molecule (VCAM) in the brain tissue of diabetic BALB/c male mice by real-time quantitative polymerase chain reaction (PCR)...
July 28, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27424492/multi-center-prospective-evaluation-of-discharge-criteria-for-hospitalized-patients-with-crimean-congo-hemorrhagic-fever
#13
Hakan Leblebicioglu, Mustafa Sunbul, Sener Barut, Seyit Ali Buyuktuna, Zulal Ozkurt, Derya Yapar, Gurdal Yilmaz, Rahmet Guner, Ayse But, Gonul Cicek Senturk, Naci Murat, Resat Ozaras
INTRODUCTION: The information of discharge criteria in patients with Crimean-Congo Hemorrhagic Fever (CCHF) is limited. In this study, we aimed to determine the clinical and laboratory parameters used in discharging the patients by the experienced centers. MATERIALS AND METHODS: The study was done in 9 reference centers of CCHF from May 1, 2015 to December 1, 2015 and included laboratory-confirmed patients with CCHF. The study was prospective, observational and non-interventional...
September 2016: Antiviral Research
https://www.readbyqxmd.com/read/27422169/somatosensory-attention-identifies-both-overt-and-covert-awareness-in-disorders-of-consciousness
#14
Raechelle M Gibson, Srivas Chennu, Davinia Fernández-Espejo, Lorina Naci, Adrian M Owen, Damian Cruse
OBJECTIVE: Some patients diagnosed with disorders of consciousness retain sensory and cognitive abilities beyond those apparent from their overt behavior. Characterizing these covert abilities is crucial for diagnosis, prognosis, and medical ethics. This multimodal study investigates the relationship between electroencephalographic evidence for perceptual/cognitive preservation and both overt and covert markers of awareness. METHODS: Fourteen patients with severe brain injuries were evaluated with an electroencephalographic vibrotactile attention task designed to identify a hierarchy of residual somatosensory and cognitive abilities: (1) somatosensory steady-state evoked responses, (2) bottom-up attention orienting (P3a event-related potential), and (3) top-down attention (P3b event-related potential)...
September 2016: Annals of Neurology
https://www.readbyqxmd.com/read/27411416/prolonged-pacifier-usage-in-infancy-does-not-cause-eating-behavior-problem-later
#15
Nazan Kaymaz, Şule Yıldırım, Sibel Cevizci, Nurcan Bulur, Naci Topaloğlu, Fatih Köksal Binnetoğlu, Mustafa Tekin, Mustafa Kılıç, Elif Nursel Özmert
The objective of this study conducted in children aged 3-7 years was to determine whether pacifier use during infancy is associated with eating problems in later periods. A total of 85 children (55.2 ±12.3 months) admitted to hospital with eating problems and with no organic pathology in scans, and 97 healthy children (52.24±10.97 months) without eating problems, were assigned to case and control groups, respectively. Eating problems were classified into five groups and investigated via a questionnaire. The presence of eating problems was analyzed for association with pacifier use...
September 2015: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27398551/production-of-nanofibers-containing-the-bioactive-compound-c-phycocyanin
#16
Felipe da Silva Figueira, Juliana Garcia Gettens, Jorge Alberto Vieira Costa, Michele Greque de Morais, Caroline Costa Moraes, Susana Juliano Kalil
C-phycocyanin (C-PC) is a water-soluble phycobiliprotein present in light-harvesting antenna system of cyanobacteria. The nanostructures have not been widely evaluated, precluding improvements in stability and application of the C-PC. Electrospun nanofibers have an extremely high specific surface area due to their small diameter, they can be produced from a wide variety of polymers, and they are successfully evaluated to increase the efficacy of antitumor drugs. The incorporation of C-PC into nanofibers would allow investigations of potential uses in alternative cancer treatments and tissue engineering scaffolds...
January 2016: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/27369652/paracetamol-induced-fixed-drug-eruption-in-a-patient-with-recurrent-fever-and-rash
#17
Emine Dibek Mısırlıoğlu, Alkım Öden Akman, Emine Vezir, Özge Başaran, Nilgün Çakar, Can Naci Kocabaş
No abstract text is available yet for this article.
August 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27366542/post-operative-malignant-hyperthermia-in-a-child-after-colon-interposition
#18
Sevtap Hekimoğlu Şahin, Mustafa İnan, Burhan Aksu, Naci Öner, Alkin Çolak, Ahmet Güzel
Malignant hyperthermia (MH) is a rare and potentially life threatening fatal complication of anaesthesia. We present a 2-year-old boy with late onset MH after colon interposition to replace the oesophagus under sevoflurane anaesthesia. The patient was treated with intravenous dantrolene sodium as well as cooling and controlled ventilation. Despite treatment, the patient developed cardiopulmonary arrest at 21 hours after the operation and died. It should be kept in mind that post-operative MH may develop during these types of operations with ischaemia-reperfusion injuries...
December 2015: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/27343314/immunohistochemical-and-ultrastructural-analysis-of-the-effect-of-omega-3-on-embryonic-implantation-in-an-experimental-mouse-model
#19
Kemal Sarsmaz, Asli Goker, Serap Cilaker Micili, Bekir Ugur Ergur, Naci Kemal Kuscu
OBJECTIVE: Implantation is the first step to a healthy pregnancy. Omega-3 supplementation is common to use during pregnancy, for its antioxidant and membrane stabilising effect. In this study we have aimed to study the effect of Omega-3 supplementation on implantation in a mouse model by immunohistochemical methods and electron microscopic evaluation. MATERIALS AND METHODS: Mice were randomized into three groups to receive standard food, Omega-3 400 mg/kg and Omega-3 1000 mg/kg one menstrual cycle before mating...
June 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27337559/history-bias-study-design-and-the-unfulfilled-promise-of-pay-for-performance-policies-in-health-care
#20
Huseyin Naci, Stephen B Soumerai
No abstract text is available yet for this article.
2016: Preventing Chronic Disease
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