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Akif E Parlak, Yusuf Karagozoglu, Naci Ö Alayunt, Semra Turkoglu, Mustafa Karatepe, Metin Koparir
Thiadiazole derivatives and its metal compounds have antibacterial, antifungal, antitumoral, antiproliferative and antioxidant properties. In the study, the effects caused by thiadiazole ligand and its metal complexes upon the fatty acids and lipophilic vitamins in livers of rats were examined. The fatty acids in liver were specified by GC while the lipophilic vitamins were specified by HPLC. It was observed that the amounts of oleic acids (18:1, n-9) and monounsaturated fatty acids (MUFA) notably increased in the Mn complex group while the amounts of arachidonic acid (20:4, n-6) notably increased in the ligand group, compared to control group...
February 28, 2018: Cellular and Molecular Biology
Hakan Guvenir, Emine Dibek Misirlioglu, Ersoy Civelek, Muge Toyran, Betul Buyuktiryaki, Tayfur Ginis, Murat Capanoglu, Esra Gurkas, Alev Guven, Can Naci Kocabas
BACKGROUND: Antiepileptic drugs (AEDs) can cause hypersensitivity reactions during childhood. Studies report a wide clinical spectrum of reactions with AED use, ranging from a mild rash to severe cutaneous reactions. OBJECTIVE: The present study aims to determine the prevalence and clinical features of AED hypersensitivity reactions during childhood. METHODS: Patients who were prescribed an AED for the first time in our hospital during November 2015 and November 2016 were followed and children who developed skin rash during this period were evaluated...
February 28, 2018: Journal of Allergy and Clinical Immunology in Practice
Ali Eryilmaz, Naci Kula
The overall aim of this study was to develop the Islamic Well-Being Scale and examine the relationship between mental health and Islamic well-being. In this study, four sub-studies were performed to create the one-factor Islamic Well-Being Scale, perform a confirmatory factor analysis and validate the Islamic Well-Being Scale, differentially predict ill-being and well-being outcomes using the Islamic Well-Being Scale, and compare individuals with different Islamic belief levels using the Islamic Well-Being Scale...
March 2, 2018: Journal of Religion and Health
Dorothy L Moore
The Canadian Paediatric Society continues to encourage annual influenza vaccination for ALL children and youth ≥6 months of age. Recommendations from the National Advisory Committee on Immunization (NACI) for the 2017/2018 influenza season are not substantially changed from those of last season. NACI has conducted a review of all available vaccine effectiveness data concerning live attenuated influenza vaccine (LAIV) and concludes that current evidence supports the continued use of LAIV in Canada, although use is not currently recommended in the USA because of concern about efficacy...
February 2018: Paediatrics & Child Health
Theresa W S Tam
Canada and the USA differ in their recommendations for the use of live attenuated influenza vaccine (LAIV). The Canadian National Advisory Committee on Immunization (NACI) continues to recommend LAIV as one of the influenza vaccines available for use in children 2 to 17 years of age. The US Advisory Committee on Immunization Practices (ACIP) made an interim recommendation against the use of LAIV for the 2016 to 2017 influenza season in response to low LAIV effectiveness observed in the USA during the 2013 to 2014 to 2015 to 2016 seasons...
February 2018: Paediatrics & Child Health
Maria Salete Sandini Linden, Marcos Eugênio de Bittencourt, João Paulo De Carli, Daniela Cristina Miyagaki, Pâmela Letícia Dos Santos, Luiz Renato Paranhos, Francisco Carlos Groppo, Juliana Cama Ramacciato
PURPOSE: To evaluate the influence of subcutaneous injection nicotine in osseointegration process on different implant surfaces. METHODS: Twenty-two male rabbits were distributed into two groups according to the subcutaneous injections: (1) nicotine 3 mg/day/kg and (2) 0.9 % NaCI 3 mL/day/kg, three times a day; subgroups were then designated-machined and anodized implants were placed in the right and left tibia bones, respectively. The animals were submitted euthanasia after periods of eight weeks to determine nicotine and cotinine levels, alkaline phosphatase and biomechanical analysis...
January 2018: Acta Cirúrgica Brasileira
Burak Kocak, Osman Kizilkilic, Naci Kocer, Civan Islak
No abstract text is available yet for this article.
February 2, 2018: Journal of Neurosurgery
Ali Naci Yildiz, Tahir Metin Piskin, Mehmet Erdem Alaguney, Ozlem Kar Kurt, Ahmet Ozlu, Mustafa Kemal Başaralı
OBJECTIVES: The incidence of ODs is below expectations. The approaches of family physicians is very important. In this study, we aimed to evaluate attitudes and behaviors of family physicians about ODs. METHODS: The questionnaire was first sent to family physicians via e-mail. Of 3663 responders, 3090 replies were included to study. RESULTS: 44.1% of them stated they obtained detailed occupational history. In logistic regression analysis, physicians who obtained detailed occupational history, discussed with occupational physician about their patients' health, had education about ODs and those who stated that they wanted to receive training in ODs were more likely to refer their patient...
February 1, 2018: Archives of Environmental & Occupational Health
Gabriele F Muti, Matteo Basso
BACKGROUND: IncobotulinumtoxinA is a botulinum neurotoxin type A that is free from complexing proteins and is used in various therapeutic indications and aesthetic medicine. It is approved for the treatment of glabellar frown lines in the United States. In Europe, it is also approved for the treatment of lateral periorbital lines (crow's feet) and for the combined treatment of upper facial lines, including glabellar frown lines, crow's feet, and horizontal forehead lines. METHODS: In the present study, incobotulinumtoxinA was injected at two different dilutions to treat female subjects aged 40 to 50 years who had moderate-to-severe lateral periorbital lines at maximum contraction according to a score of 2 or 3 points on the 5-point Merz Aesthetics Scales (MAS)...
September 2017: Journal of Clinical and Aesthetic Dermatology
Hasan Celik, Mustafa Hanci, Naci Karacaoglan
No abstract text is available yet for this article.
January 11, 2018: Aesthetic Surgery Journal
İlknur Kulhas Celik, Betul Buyuktiryaki, Emine Dibek Misirlioglu, Ezgi Hasbek, Can Naci Kocabas
No abstract text is available yet for this article.
January 12, 2018: Journal of Allergy and Clinical Immunology in Practice
Huseyin Naci, Aaron S Kesselheim
No abstract text is available yet for this article.
December 26, 2017: JAMA: the Journal of the American Medical Association
Şule Yıldırım, Naci Topaloğlu, Mustafa Tekin, Fatma Sılan
We report a case of 11-year-old girl with growth retardation and 46, XX, Xq27-qter deletion. The endocrinologic evaluation revealed growth hormone deficiency. In karyotype analysis  46, XX, Xq27-qter deletion was determined. The deletion of terminal region of chromosome 27 is most commonly being detected during the evaluation of infertility, premature ovarian insufficiency or in screening for fragile X carrier status. To our knowledge, this is the first reported case with 46, XX, Xq27-qter deletion and growth hormone deficiency...
October 2017: Acta Medica Iranica
Civan Islak, Sedat Giray Kandemirli, Osman Kizilkilic, Naci Kocer, Saffet Tuzgen, Mehmet Murat Hanci
BACKGROUND: Spinal vascular malformations as a group are rare, and coexistence of a spinal arteriovenous malformation (AVM) in or around the spinal dysraphism is extremely rare. We report 2 cases of combined spinal dysraphism and vascular malformations of the spinal cord. CASE DESCRIPTION: The first case was an AVM located in a filum terminale lipoma fed by the artery of the filum terminale. This case was managed by multiple endovascular embolizations followed by surgery...
February 2018: World Neurosurgery
Akif Evren Parlak, Yusuf Karagozoglu, Naci O Alayunt, Semra Turkoglu, Isil Yildirim, Mustafa Karatepe, Metin Koparir
In this study, it was aimed to examine the antioxidant and antihepatotoxic effects of hydroxyurea derivative Schiff bases on serum biochemical parameters (AST, ALT, LDH, urea, creatinine and total bilirubin) and antioxidant parameters (SOD, CAT, GPx, MDA). In this study, a total of 49 adult male Wistar rats was examined and they were divided into 7 equal groups. DMSO, which is diluted only with corn oil, was administered to control group. 25 mg / kg ligand, 25 mg / kg Schiff base - manganese, 25 mg / kg Schiff base-copper, 25 mg / kg Schiff base - zinc, 25 mg / kg Schiff base - nickel, 25 mg / kg Schiff base - cobalt complexes were administered to rats of experimental group subcutaneously for 15 days with three-day intervals throughout the test process...
November 30, 2017: Cellular and Molecular Biology
Huseyin Naci, Paulus Kirchhof, Alec Vahanian, Jan Steffel, Isabel Bardinet, Elias Mossialos, Panos Vardas
No abstract text is available yet for this article.
December 1, 2017: European Heart Journal
Naci Parlak, Yasemin Görgülü, Rugül Köse Çinar, Mehmet Bülent Sönmez, Ebru Parlak
Orexigenic and anorexigenic peptides, especially agouti-related protein (AgRP) and leptin, play important roles in the regulation of energy homeostasis in bipolar disorder. AgRP regulates energy metabolism by increasing appetite and decreasing energy expenditure. The resting energy expenditures of patients with manic bipolar disorder are higher than those of controls. Due to the effects of AgRP on energy expenditure and the increased physical activity of manic patients, we hypothesised that serum AgRP levels may be lower in manic patients than in euthymic patients and controls...
November 6, 2017: Psychiatry Research
Maria-Salete-Sandini Linden, Luiz-Renato Paranhos, João-Paulo De Carli, Micheline-Sandini Trentin, Marcos-Eugênio de Bittencourt, Pâmela-Letícia Santos, Francisco-Carlos Groppo, Juliana-Camma Ramacciato
Background: The nicotine may generate a influence on bone repair and longevity of dental implants. This fact makes studies to improve the surface of the implants are constantly conducted. This study aimed to evaluate the influence of subcutaneous nicotine injection in the osseointegration process on different implant surfaces, through histomorphometric analysis. Material and Methods: Therefore, twenty-two male rabbits were randomly distributed into two groups according to the subcutaneous injections: (1) nicotine, 3 mg/day/kg and (2) 0...
October 2017: Journal of Clinical and Experimental Dentistry
Huseyin Naci, Elias Mossialos
No abstract text is available yet for this article.
November 22, 2017: BMJ: British Medical Journal
Naci Balak, Ece Balkuv, Ali Karadag, Recep Basaran, Huseyin Biceroglu, Buruç Erkan, Necmettin Tanriover
Very recently, neuromodulation through deep brain stimulation (DBS) has appeared as a new surgical procedure in the treatment of some types of dementia and epilepsy. The mammillothalamic and the mammillotegmental tracts are involved among the new targets. To our knowledge, a review article focused specifically on these mammillary body efferents is lacking in the medical literature. Their contribution to memory is, regrettably, often overlooked. There is evidence that mammillary bodies can contribute to memory independently from hippocampal formation, but the mechanism is not yet known...
November 9, 2017: World Neurosurgery
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