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Maxillary sinus cancer

Giovanni Salzano, Mario Turri-Zanoni, Apostolos Karligkiotis, Jacopo Zocchi, Giovanni Dell'Aversana Orabona, Luigi Califano, Paolo Battaglia, Paolo Castelnuovo
BACKGROUND: The infraorbital nerve (ION) is a terminal branch of the maxillary nerve (V2) providing sensory innervation to the malar skin. It is sometimes necessary to sacrifice the ION and its branches to obtain adequate maxillary sinus exposure for radical resection of sinonasal tumors. Consequently, patients suffer temporary or permanent paresthesia, hypoestesthia, and neuralgia of the face. We describe an innovative technique used for preservation of the ION while removing the anterior, superior, and lateral walls of the maxillary sinus through a medial endoscopic transnasal maxillectomy...
September 28, 2016: International Forum of Allergy & Rhinology
Theresa M Hofstede, Rhonda F Jacob, Patricia Montgomery, Peggy Wesley
BACKGROUND: Skin cancers requiring nasal resection may be surgically reconstructed and/or prosthetically reconstructed. Singular surgical reconstruction may be ideal for smaller defects in which the nasal bone and cartilaginous portions of the nose are maintained, but surgical reconstruction falls short of providing acceptable aesthetic results for more extensive nasal defects. Prosthetic rehabilitation, or a combination of surgical and prosthetic rehabilitation, is more appropriate for larger defects, but prosthesis retention can be challenging when adhesives are required on adjacent mobile and secreting skin...
September 12, 2016: Head & Neck
G Peyraga, C Lafond, Y Pointreau, P Giraud, P Maingon
The nasal cavity and parasinusal cancer are rare (10% of tumors of the head and neck) and are mainly represented by squamous cell carcinoma of the nasal cavity or the maxillary sinus and adenocarcinoma of the ethmoid sinus (occupational disease, wood dust). The most common clinical sign is nasal obstruction, but tumors can also manifest as rhinorrhea and/or epistaxis (usually unilateral signs). A magnetic resonance imaging of the facial structure is systematic for staging before treatment. The treatment consists of a first surgery if the patient is operable with a resectable tumor...
September 2016: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
Yong Gao, Xiao Yan, Mengyun Lai, Peng Guo, Yafei Wu, Shangyong Zhu
RATIONALE AND OBJECTIVES: Accurate staging forms the basis for the successful management of maxillary sinus carcinoma. The purpose of this study was to compare the efficacy of ultrasonography and computed tomography (CT) for detection and T-staging of maxillary sinus carcinoma. MATERIAL AND METHODS: T-staging of maxillary sinus carcinoma by ultrasonography and CT was studied in 37 patients: 25 with squamous cell carcinoma and 12 with tumors of other histologic types...
June 2016: Discovery Medicine
Thiago Henrique Martins, João Paulo Bonardi, Glaykon Alex Vitti Stabile, Fabio Augusto Ito, Cecilia Luiz Pereira-Stabile, Eduardo Hochuli-Vieira
Carcinomas of salivary glands are rare and can affect major or minor salivary glands. Among them, the mucoepidermoid carcinoma is the most prevalent and its occurrence in the first 2 decades of life is highly unusual. Their common clinical aspect to different diseases is a challenge in diagnosis. The objective of this work is to elucidate the diagnosis of lesion in the hard palate of an adolescent patient, brown-skinned, male, forwarded to the oral surgery department at the State University of Londrina. Initially, he complained about a progressive swelling in the last 60 days...
October 2016: Journal of Craniofacial Surgery
Joshua Smith, Andrew C Birkeland, Jonathan B McHugh, Matthew E Spector
Bisphosphonate-induced osteonecrosis of the mandible and/or maxilla is an increasingly recognized, though still rare complication of bisphosphonate therapy. In the present case, the patient presented with a seven-month history of maxillary sinusitis and pain, and was originally diagnosed with a bony metastasis from her primary breast cancer. However, surgical excision and biopsy led to a diagnosis of bisphosphonate-induced osteonecrosis of the maxilla. As bisphosphonates are often prescribed for patients with metastatic disease, it is important to recognize that bisphosphonate-induced osteonecrosis may present similarly to bony metastases...
2016: Journal of Case Reports in Medicine
Vijay M Patil, Vanita Noronh, Amit Joshi, Ashay Karpe, Vikas Talreja, Arun Chandrasekharan, Sachin Dhumal, Kumar Prabhash
BACKGROUND: Metronomic chemotherapy consisting of methotrexate and celecoxib recently has shown promising results in multiple studies in head and neck cancers. However, these studies have not included patients with maxillary sinus primaries. Hence, the role of palliative metronomic chemotherapy in patients with maxillary sinus carcinoma that is not amenable to radical therapy is unknown. METHODS: This was a retrospective analysis of carcinoma maxillary sinus patients who received palliative metronomic chemotherapy between August 2011 and August 2014...
April 2016: South Asian Journal of Cancer
Wenqing Liang, Qianqian Li, Tian Zhang
A 59-year-old man was admitted to the Department of Ear, Nose and Throat with a complaint of six-month history of left facial numbness and toothache. There was no special previous medical history in addition to smoking. No obvious abnormality in routine electrocardiogram, chest X-ray, abdominal B ultrasound were found. (1) CT scans showed heterogeneous shadows in maxillary sinus with the lesions on the left max- illary bone and evidently destruction of alveolar bone. The histopathological examination revealed bone tissue which was partly covered by an intact adenocarcinoma cell...
January 2016: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Seung Min Lee, You Me Kim, Bong Man Kim
The paranasal sinuses are known to be a rare location for metastasis. Renal cell carcinoma (RCC) is the most frequent primary tumor to metastasize to the sinonasal region, followed by lung and breast cancer. In particular, clear cell type RCC, which represents approximately 85% of RCCs, is characterized by early metastasis, and it sometimes spreads to unusual sites (1, 2). Metastatic tumors in the paranasal sinuses are distributed in the maxillary, sphenoid, ethmoid, and frontal sinuses, in order of decreasing frequency...
January 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
Rami Abo-Shasha, Camilla Stepniak, David H Yeh, Brian Rotenberg
INTRODUCTION: We report on a case of isolated metastatic breast cancer to the medial rectus muscle. This entity is exceedingly rare. CASE: A 44-year-old female with a history of breast cancer presented with unilateral maxillary symptoms and was treated for sinusitis. Over time, she developed ocular pain, diplopia, blurred vision and eventually complete adduction deficit. RESULTS: T1-weighted magnetic resonance imaging revealed a medial rectus lesion...
January 2016: Allergy & Rhinology
Emmanuel A Oga, Lisa M Schumaker, Biodun Sulyman Alabi, Darlington Obaseki, Aniefon Umana, Ima-Abasi Bassey, Godwin Ebughe, Olabode Oluwole, Teniola Akeredolu, Sally N Adebamowo, Patrick Dakum, Kevin Cullen, Clement A Adebamowo
INTRODUCTION: The burden of HPV-related Head and Neck Cancers (HNC) has been rising in the U.S. and other developed countries but this trend has not been reported in Africa. Objective of study was to evaluate the prevalence of HPV infection in HNC cancer cases seen between 1990 and 2011 at the tertiary health care institutions in Nigeria. METHODS: We retrieved 149 head and neck cancer formalin fixed, paraffin embedded tumor specimens diagnosed between 1990 and 2011 from four teaching hospitals in Nigeria...
2016: PloS One
Tian Tang, Qing Jie Xia, Xiaoming Qiao, Mingrong Xi
INTRODUCTION: C-X-C chemokine receptor type 7 (CXCR7) has recently been characterised as a novel receptor for the C-X-C motif chemokine 12 (CXCL12)/stromal cell-derived factor 1-alpha. CXCR7 has been thought to play an important role in the pathogenesis of chronic rhinosinusitis, angiogenesis and tumour metastasis. The present study aimed to examine the expression of CXCR7 in tissue samples of laryngeal cancer and maxillary sinus carcinoma to determine its role in the development of otorhinolaryngologic neoplasms...
March 2016: Singapore Medical Journal
Kousuke Yoshifuku, Kengo Nishimoto, Tsutomu Matsuzaki, Shigeto Matsushita
Herein, we report a case of drug-induced Stevens Johnson syndrome. (SJS). A 56-year old female visited our hospital complaining of right cheek pain. Local examination revealed that the right ostium of the maxillary sinus was open and that the maxillary sinus mucosa was invaded by tumor. Biopsy revealed a histopathological diagnosis of squamous cell carcinoma. We therefore diagnosed the patient as a case of maxillary sinus carcinoma (T3N0M0) based on the CT, MRI and FDG-PET findings. During chemoradiotherapy for maxillary sinus cancer, the patient developed oral mucosal inflammation of progressively worsening severity; we initially thought that the symptom was a side effect of the treatment; however, several days later, skin lesions appeared throughout the body...
December 2015: Nihon Jibiinkoka Gakkai Kaiho
I Ates, O Yazici, H Ates, N Ozdemir, N Zengin
Lung adenocarcinoma often makes metastasis to the brain, liver, kidneys, bone, bone marrow and adrenal glands. It can also make metastasis to other parts of the body rarely for example eye, nose, parotid gland and paranasal sinus. We did not encounter with combined ocular bulbus and the maxillary sinus metastases of lung cancer in the accessible literature. In this case report, a patient who was combined ocular bulbus and the maxillary sinus metastases of lung adenocarcinoma will be discussed.
September 2015: Experimental Oncology
Hiroshi Doi, Kazuhiro Kitajima, Kazuhito Fukushima, Yusuke Kawanaka, Miya Mouri, Satoshi Yamamoto, Reiichi Ishikura, Tomonori Terada, Kazuma Noguchi, Shozo Hirota
PURPOSE: Our aim was to determine whether the maximum standardized uptake value (SUVmax) of the primary lesion demonstrated by [(18)F]-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) is associated with the prognosis of maxillary sinus cancer. MATERIALS AND METHODS: The relationships of clinicopathological factors including age, T stage, N stage, histologic type, treatment strategy, and primary tumor SUVmax with progression-free (PFS) and overall (OS) survival were evaluated using the log-rank test and Cox method in 31 patients with maxillary sinus cancer before combined superselective intra-arterial chemotherapy using high-dose cisplatin with concurrent radiotherapy, or radiotherapy alone...
May 2016: Japanese Journal of Radiology
Nadia Shirazi, Sampan S Bist, Thamarai N Selvi, Meena Harsh
OBJECTIVE: Sinonasal tumors are a highly heterogeneous group of tumors that account for less than 1% of all cancers. Precise diagnosis is essential because the natural history, treatment, and prognosis vary for different neoplasms. We reviewed 610 cases of sinonasal lesions to understand this entity better. METHODS: A total of 610 sinonasal biopsies/specimens were received over a period of 10 years (2004-14). All the samples were processed and stained with hematoxylin and eosin...
November 2015: Oman Medical Journal
Swati Agrawal, Kumar Jayant, Rajendra Kumar Agarwal, Kalyan G Dayama, Seema Arora
Metastatic breast carcinoma has been described to the various areas in the head and neck region. However, these metastases are rarely found in nasopharynx. Herein we are presenting the first case of male breast carcinoma with the longest survival secondary to distant metastases in right maxillary sinus and extending to the nasopharynx with extensive skeletal & lung metastases. Here we present a case of 65-year-old male with past medical history of right breast carcinoma, presented clinically with symptoms of recurrent sinusitis...
October 2015: Annals of Palliative Medicine
Paolo Bossi, Davide Farina, Gemma Gatta, Davide Lombardi, Piero Nicolai, Ester Orlandi
Paranasal sinus cancers are rare diseases, accounting for about 5% of all head and neck malignancies. The variety of histological types and the overlapping pathological features with other entities constitute difficulties in pathologic interpretation, often requiring a skilled interpretation or a second opinion. Treatment of locally advanced disease relies on surgery and radiation therapy for operable disease, with a possible role for systemic treatment in selected histologies within a multimodal approach; unresectable paranasal sinus cancers are generally treated with a combination of radiotherapy and chemotherapy...
February 2016: Critical Reviews in Oncology/hematology
Wei Wang, Xiaodong Zhan, Hualong Qiang, Zhongqiang Cheng
OBJECTIVE: A retrospective analysis of the clinical efficacy on the surgery of maxillary sinus diseases via the endoscopic lateral nasal wall incision, and a discussion on the clinical application of this approach. METHOD: Eighteen cases of the maxillary sinus diseases diagnosed on the basis of the preoperative nasal endoscopy, CT scan or MRI, and pathologic finding. Among 13 patients underwent routine lateral nasal wall incision approach, including 4 of maxillary sinus hemorrhagic and necrotic polyps, 4 of maxillary sinus cyst, and 3 of the maxillary sinus fungal infection...
June 2015: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Mareike Knör, Konstantin Tziridis, Abbas Agaimy, Johannes Zenk, Olaf Wendler
OBJECTIVES: The pathogenesis of sinonasal polyposis remains unclear, in spite of several investigative approaches. Antrochoanal polyps, a subgroup of sinonasal polyposis along with allergic- and chronic-inflammatory nasal polyps, mostly originate from the maxillary sinus and develop as a unilateral, pedunculated mass towards the nasopharynx. The human papillomavirus (HPV) is discussed as a possible causative and influencing factor in development and progression of sinonasal polyposis...
2015: PloS One
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