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Feeding and eating disorders

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https://www.readbyqxmd.com/read/29134507/prevalence-and-characteristics-of-orthorexia-nervosa-in-a-sample-of-university-students-in-italy
#1
L Dell'Osso, Barbara Carpita, D Muti, I M Cremone, G Massimetti, E Diadema, C Gesi, C Carmassi
AIMS: Orthorexia nervosa (ON) has been recently defined as a pathological approach to feeding related to healthiness concerns and purity of food and/or feeding habits. This condition recently showed an increasing prevalence particularly among young adults. In order to investigate the prevalence of ON and its relationship with gender and nutritional style among young adults, we explored a sample of students from the University of Pisa, Italy. METHODS: Assessments included the ORTO-15 questionnaire and a socio-demographic and eating habits form...
November 13, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29097161/a-behavioral-and-pharmacological-characterization-of-palatable-diet-alternation-in-mice
#2
Catherine F Moore, Gabrielle S Schlain, Samantha Mancino, Valentina Sabino, Pietro Cottone
Obesity and eating disorders are widespread in Western societies. Both the increased availability of highly palatable foods and dieting are major risk factors contributing to the epidemic of disorders of feeding. The purpose of this study was to characterize an animal model of maladaptive feeding induced by intermittent access to a palatable diet alternation in mice. In this study, mice were either continuously provided with standard chow food (Chow/Chow), or provided with standard chow for 2days and a high-sucrose, palatable food for 1day (Chow/Palatable)...
October 31, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/29091821/are-gastrointestinal-and-sleep-problems-associated-with-behavioral-symptoms-of-autism-spectrum-disorder
#3
Xiao-Lei Yang, Shuang Liang, Ming-Yang Zou, Cai-Hong Sun, Pan-Pan Han, Xi-Tao Jiang, Wei Xia, Li-Jie Wu
Many children with autism spectrum disorder (ASD) suffer from concurrent medical symptoms, including gastrointestinal (GI) and sleeping problems. However, there is limited information on the correlation between co-morbidities and autistic behavioral symptoms. In this study, we estimated the prevalence of GI and sleep problems in Chinese ASD children, examined the impacts of GI and sleep problems on autistic behavioral symptoms, and investigated the factors associated with GI and sleep problems. The survey included 169 ASD and 172 healthy children...
October 24, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29091129/feeding-difficulties-in-preschool-children-previous-feeding-practices-and-nutritional-status
#4
Hélcio de Sousa Maranhão, Renata Cunha de Aguiar, Débora Teixeira Jales de Lira, Mônica Úrsula Figuerêdo Sales, Nathalia Ávila do Nascimento Nóbrega
OBJECTIVE: To identify the prevalence of feeding difficulties in preschoolers, its association with epidemiological factors and previous eating habits, and repercussion on nutritional status. METHODS: Cross-sectional study with a questionnaire given to the mothers of 301 children aged 2-6 years enrolled in public and private kindergartens in Natal, Northeast Brazil, conducted in 2014-2015. Feeding difficulty was assessed according to Kerzner's criteria, resulting in the profiles "highly selective intake", "active child with small appetite", "fear of feeding", and "child with psychological disorder or neglected"...
October 30, 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29068721/adjunctive-use-of-olanzapine-in-the-treatment-of-avoidant-restrictive-food-intake-disorder-in-children-and-adolescents-in-an-eating-disorders-program
#5
Timothy D Brewerton, Meredith D'Agostino
OBJECTIVE: There is little information about the pharmacological treatment of avoidant and restrictive food intake disorder (ARFID), a challenging feeding disorder associated with marked impairment and developmental arrest. This brief clinical report seeks to fill this gap. METHODS: A retrospective chart review of nine patients with ARFID treated in an eating disorder (ED) program (residential, partial hospital, and intensive outpatient levels of care) with adjunctive olanzapine was undertaken...
October 25, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29052014/predictive-validity-of-a-service-setting-based-measure-to-identify-infancy-mental-health-problems-a-population-based-cohort-study
#6
Janni Ammitzbøll, Lau Caspar Thygesen, Bjørn E Holstein, Anette Andersen, Anne Mette Skovgaard
Measures to identify infancy mental health problems are essential to guide interventions and reduce the risk of developmental psychopathology in early years. We investigated a new service-setting-based measure the Copenhagen Infant Mental Health Screening (CIMHS) within the general child health surveillance by community health nurses (CHN). The study population of 2973 infants was assessed by CIMHS at age 9-10 months. A subsample of 416 children was examined at age 1½ years, using parent interviews including the Child Behavior Checklist (CBCL 1½-5), Check List of Autism and Toddlers (CHAT), Infant-Toddler Symptom Checklist (ITSCL), and the Bayley Scales of Infant and Toddler Development (BSID) and observations of behavior, communication, and interaction...
October 20, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29049935/intranasal-oxytocin-in-the-treatment-of-anorexia-nervosa-randomized-controlled-trial-during-re-feeding
#7
Janice Russell, Sarah Maguire, Glenn E Hunt, Alice Kesby, Anastasia Suraev, Jordyn Stuart, Jessica Booth, Iain S McGregor
BACKGROUND: Nutritional rehabilitation in anorexia nervosa (AN) is impeded by fear of food, eating and change leading to treatment resistance. Oxytocin (OT) exerts prosocial effects and modulates trust, fear, anxiety and neuroplasticity. The current placebo-controlled RCT examined the effects of intranasal oxytocin (IN-OT) in AN. The aim was to ascertain whether repeated doses of IN-OT enhance treatment outcomes in AN. METHODS: AN patients self-administered 36 IU IN-OT or placebo daily for 4-6 weeks during hospital treatment...
October 14, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28994619/biological-evaluation-of-benzosuberones
#8
Haider Behbehani, Kamal M Dawood, Thoraya A Farghaly
Several natural products containing benzosuberone moiety are clinically reported as anti-tumor agents. Furthermore, several synthetic benzosuberones cited in this review exhibited wide range of theraputic activities such as bacteriostatic, anti-inflammatory, antidepressants and anti-tumor activities. Our recent review provides an overview of the different methods to synthesize the benzosuberones and their extensive biological activities. Areas covered: Thirty-two patents among 130 references are cited in this review that covered the recent inhibitory activities of the benzosuberone scaffolds and their broad area of biological applications up to the first quarter of 2017...
October 10, 2017: Expert Opinion on Therapeutic Patents
https://www.readbyqxmd.com/read/28991767/anorexia-anormal-phobia-of-normal-weight
#9
Nada Pop-Jordanova, Tatjana Zorcec, Aneta Demerdzieva
Anorexia nervosa is a disorder of feeding behavior associated with distortion of body image, mood disturbance and a wide variety of hormonal and metabolic abnormalities. It is supposed that the disease could be the consequence of a combination of cultural-social, psychological and biological factors. Our study confirmed that anorexia mentalis is a serious, life threatening disorder which in our country appears earlier than it was expected and that is strongly related to environmental factors (family, school, fashion, society)...
September 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/28955242/shortened-spadin-analogs-display-better-trek-1-inhibition-in-vivo-stability-and-antidepressant-activity
#10
Alaeddine Djillani, Mariel Pietri, Sébastien Moreno, Catherine Heurteaux, Jean Mazella, Marc Borsotto
Depression is a devastating mental disorder that affects 20% of the population worldwide. Despite their proven efficacy, antidepressants present a delayed onset of action and serious adverse effects. Seven years ago, we described spadin (PE 12-28) as a promising endogenous peptide with antidepressant activity. Spadin specifically blocks the TREK-1 channel. Previously, we showed in vivo that, spadin activity disappeared beyond 7 h after administration. In order to improve in vivo spadin stability and bioavailability, we screened spadin analogs and derivatives...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28955139/the-latent-class-structure-of-chinese-patients-with-eating-disorders-in-shanghai
#11
Yuchen Zheng, Qing Kang, Jiabin Huang, Wenhui Jiang, Qiang Liu, Han Chen, Qing Fan, Zhen Wang, Jue Chen, Zeping Xiao
BACKGROUND: Eating disorder is culture related, and the clinical symptoms are different between eastern and western patients. So the validity of feeding and eating disorders in the upcoming ICD-11 guide for Chinese patients is unclear. AIMS: To explore the latent class structure of Chinese patients with eating disorder and the cross-cultural validity of the eating disorder section of the new ICD-11 guide in China. METHODS: A total of 379 patients with eating disorders at Shanghai Mental Health Center were evaluated using the EDI questionnaire and a questionnaire developed by researchers from 2010 to 2016...
August 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28951234/activity-based-anorexia-activates-nesfatin-1-immunoreactive-neurons-in-distinct-brain-nuclei-of-female-rats
#12
Sophie Scharner, Philip Prinz, Miriam Goebel-Stengel, Reinhard Lommel, Peter Kobelt, Tobias Hofmann, Matthias Rose, Andreas Stengel
Activity-based anorexia (ABA) is an established animal model for the eating disorder anorexia nervosa (AN). The pathophysiology of AN and the involvement of food intake-regulatory peptides is still poorly understood. Nesfatin-1, an anorexigenic peptide also involved in the mediation of stress, anxiety and depression might be a likely candidate involved in the pathogenesis of AN. Therefore, activation of nesfatin-1 immunoreactive (ir) brain nuclei was investigated under conditions of ABA. Female Sprague-Dawley rats were used and divided into four groups (n=6/group): activity-based anorexia (ABA), restricted feeding (RF), activity (AC) and ad libitum fed (AL)...
December 15, 2017: Brain Research
https://www.readbyqxmd.com/read/28948079/influence-of-tfap2b-and-kctd15-genetic-variability-on-personality-dimensions-in-anorexia-and-bulimia-nervosa
#13
Carmen Gamero-Villarroel, Luz M González, Raquel Rodríguez-López, David Albuquerque, Juan A Carrillo, Angustias García-Herráiz, Isalud Flores, Guillermo Gervasini
INTRODUCTION: TFAP2B and KCTD15 are obesity-related genes that interact to regulate feeding behavior. We hypothesize that variability in these loci, isolated or in combination, could also be related to the risk of eating disorders (ED) and/or associated psychological traits. METHODS: We screened 425 participants (169 ED patients, 75 obese subjects, and 181 controls) for 10 clinically relevant and tag single-nucleotide polymorphisms (SNPs) in KCTD15 and TFAP2B by the Sequenom MassARRAY platform and direct sequencing...
September 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28946763/dissociation-in-psychiatric-disorders-a-meta-analysis-of-studies-using-the-dissociative-experiences-scale
#14
Lisa Lyssenko, Christian Schmahl, Laura Bockhacker, Ruben Vonderlin, Martin Bohus, Nikolaus Kleindienst
OBJECTIVE: Dissociation is a complex, ubiquitous construct in psychopathology. Symptoms of dissociation are present in a variety of mental disorders and have been connected to higher burden of illness and poorer treatment response, and not only in disorders with high levels of dissociation. This meta-analysis offers a systematic and evidence-based study of the prevalence and distribution of dissociation, as assessed by the Dissociative Experiences Scale, within different categories of mental disorders, and it updates an earlier meta-analysis...
September 26, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28942809/reduced-inferior-and-orbital-frontal-thickness-in-adolescent-bulimia-nervosa-persists-over-two-year-follow-up
#15
Marilyn Cyr, Daniel C Kopala-Sibley, Seonjoo Lee, Chen Chen, Mihaela Stefan, Martine Fontaine, Kate Terranova, Laura A Berner, Rachel Marsh
OBJECTIVE: Cross-sectional data suggest functional and anatomical disturbances in inferior and orbital frontal regions in bulimia nervosa (BN). Using longitudinal data, we investigated whether reduced cortical thickness (CT) in these regions arises early and persists over adolescence in BN, independent of symptom remission, and whether CT reductions are markers of BN symptoms. METHOD: A total of 33 adolescent females with BN symptoms (BN or other specified feeding or eating disorder) and 28 healthy adolescents participated in this study...
October 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28938790/factors-affecting-adipose-tissue-development-in-chickens-a-review
#16
Guoqing Wang, Woo Kyun Kim, Mark A Cline, Elizabeth R Gilbert
The intense genetic selection for rapid growth in broilers has resulted in an increase in voluntary feed intake and growth rate, accompanied by increased fat deposition in adipose tissue depots throughout the body. Adipose tissue expansion is a result of the formation of adipocytes (several processes collectively referred to as adipogenesis) and cellular accumulation of triacylglycerols inside lipid droplets. In mammals, different anatomical depots are metabolically distinct. The molecular and cellular mechanisms underlying adipose tissue development have been characterized in mammalian models, whereas information in avian species is scarce...
October 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28901678/improving-inhibitory-control-abilities-impulse-a-promising-approach-to-treat-impulsive-eating
#17
Hanna Preuss, Marlies Pinnow, Katja Schnicker, Tanja Legenbauer
Although there is preliminary evidence that inhibitory control training improves impulsive eating, less is known about the effects on eating behaviour and weight loss in clinical samples. Sixty-nine treatment-seeking adults with obesity (binge-eating disorder 33.3%; other specific feeding and eating disorders 40.6%) were randomly blockwise allocated to ImpulsE, an intervention to improve inhibitory control and emotion regulation abilities or a guideline-appropriate cognitive behavioural therapy (CBT)-based treatment as usual...
November 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28877337/parent-reported-indicators-for-detecting-feeding-and-swallowing-difficulties-and-undernutrition-in-preschool-aged-children-with-cerebral-palsy
#18
Katherine A Benfer, Kelly A Weir, Robert S Ware, Peter S W Davies, Joan Arvedson, Roslyn N Boyd, Kristie L Bell
AIM: To determine the most accurate parent-reported indicators for detecting (1) feeding/swallowing difficulties and (2) undernutrition in preschool-aged children with cerebral palsy (CP). METHOD: This was a longitudinal, population-based study, involving 179 children with CP, aged 18 to 60 months (mean 34.1mo [SD 11.9] at entry, 111 males, 68 females [Gross Motor Function Classification System level I, 84; II, 23; III, 28; IV, 18; V, 26], 423 data points). Feeding/swallowing difficulties were determined by the Dysphagia Disorders Survey and 16 signs suggestive of pharyngeal phase impairment...
November 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28872733/cafeteria-diet-induces-neuroplastic-modifications-in-the-nucleus-accumbens-mediated-by-microglia-activation
#19
Miriam Gutiérrez-Martos, Benoit Girard, Sueli Mendonça-Netto, Julie Perroy, Emmanuel Valjent, Rafael Maldonado, Miquel Martin
High-palatable and caloric foods are widely overconsumed due to hedonic mechanisms that prevail over caloric necessities leading to overeating and overweight. The nucleus accumbens (NAc) is a key brain area modulating the reinforcing effects of palatable foods and is crucially involved in the development of eating disorders. We describe that prolonged exposure to high-caloric chocolate cafeteria diet leads to overeating and overweight in mice. NAc functionality was altered in these mice, presenting structural plasticity modifications in medium spiny neurons, increased expression of neuroinflammatory factors and activated microglia, and abnormal responses after amphetamine-induced hyperlocomotion...
September 5, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28866711/icd-11-draft-diagnostic-guidelines-for-mental-disorders-a-report-for-wpa-membership
#20
REVIEW
Gaia Sampogna
The 11th edition of the International Classification of Diseases (ICD-11) is scheduled for approval by the World Health Assembly in May 2018. The chapter on mental disorders is currently under development. A draft of the clinical descriptions and diagnostic guidelines for all the disorders has been produced by the relevant Working Groups. A simplified version of the diagnostic guidelines for some disorders (i.e., schizophrenia and other primary psychotic disorders, mood disorders, anxiety disorders, disorders specifically associated with stress, and feeding and eating disorders) has been made available for use in the field studies of the classification...
June 18, 2017: Psychiatria Polska
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