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Fluorescense angiography

Masaki Yamamoto, Hideaki Nishimori, Takashi Fukutomi, Takemi Handa, Kazuki Kihara, Miwa Tashiro, Takayuki Sato, Kazumasa Orihashi
PURPOSE: Although useful for visualizing blood flow during revascularization surgery, the permeability of near-infrared fluorescence (NIR) angiography using indocyanine green (ICG) does not allow for vessel stenosis visualization. We hypothesized that changes in ICG fluorescence intensity reflect vessel stenosis, and evaluated the influence of stenosis on blood flow by ex vivo experimentation. METHODS: The vessel stenosis model comprised a silicon tube, a graft occluder, and artificial blood...
July 2017: Surgery Today
Nathan Lassota, Jens Folke Kiilgaard, Jan Ulrik Prause, Klaus Qvortrup, Erik Scherfig, Morten la Cour
PURPOSE: To develop a reproducible surgical technique for the induction of choroidal neovascularization (CNV) in the subretinal space of porcine eyes and to analyse the resulting CNV clinically and histologically. METHODS: Two different modifications of a surgical technique previously described were compared with the original method. In ten porcine eyes retinal pigment epithelial (RPE) cells were removed using a silicone tipped cannula, in ten porcine eyes Bruch's membrane was perforated once with a retinal perforator without prior RPE removal and in ten eyes RPE removal was followed by a single perforation of Bruch's membrane...
August 2007: Graefe's Archive for Clinical and Experimental Ophthalmology
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