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APACHE II

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https://www.readbyqxmd.com/read/29765435/mortality-of-adult-intensive-care-units-in-turkey-using-the-apache-ii-and-sofa-systems-outcome-assessment-in-turkish-intensive-care-units
#1
Cetin Kaymak, Irfan Sencan, Seval Izdes, Aydin Sari, Hatice Yagmurdur, Derya Karadas, Derya Oztuna
Introduction: The aim of this study was to evaluate intensive care unit (ICU) performance using risk-adjusted ICU mortality rates nationally, assessing patients who died or had been discharged from the ICU. For this purpose, this study analyzed the Acute Physiology and Chronic Health Evaluation (APACHE) II and Sequential Organ Failure Assessment (SOFA) databases, containing detailed clinical and physiological information and mortality of mixed critically ill patients in a medical ICU at secondary and tertiary referral ICUs in Turkey...
April 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29764554/-efficacy-and-safety-of-nalbuphine-on-analgesia-of-patients-in-intensive-care-unit
#2
Shaohua Liu, Youdong Wan, Yonggang Luo, Li Wan, Wenjing Yun, Haixu Wang, Zhenhua Wang, Xiaoguang Duan, Ruifang Zhang, Yingying Zhao, Hongwei Cui, Tongwen Sun
OBJECTIVE: To analyze the efficacy and safety of nalbuphine in patients with sedative analgesia in intensive care unit (ICU). METHODS: A prospective observation was conducted. The adult patients with mild and moderate analgesia in general ICU of the First Affiliated Hospital of Zhengzhou University from January to November in 2017 were enrolled, and they were divided into nalbuphine group and sufentanil group in proper order. The nabobrown group was given 40 mg nabobrown, the sufentanil group was given 0...
May 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29764551/-predictive-values-of-different-critical-scoring-systems-for-survival-rate-after-discharge-in-critically-ill-patients-supported-by-extracorporeal-membrane-oxygenation
#3
Jinsong Zhang, Wei Li, Xufeng Chen, Yong Mei, Jinru Lyu, Deliang Hu, Gang Zhang, Yongxia Gao, Xihua Huang
OBJECTIVE: To determine the predictive values of different critical scoring systems for survival rate after discharge in critically ill patients supported by extracorporeal membrane oxygenation (ECMO). METHODS: The clinical data of 34 critically ill patients supported by ECMO admitted to Department of Emergency of the First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital) from July 2015 to September 2017 were retrospectively analyzed...
May 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29762825/the-prognostic-role-of-platelet-to-lymphocyte-ratio-and-mean-platelet-volume-in-critically-ill-patients
#4
A Yildiz, A Yigit, A R Benli
OBJECTIVE: The aim of this study was to identify the relationship between complete blood count parameters, mean platelet volume (MPV), and platelet to lymphocyte ratio (PLR) with mortality and hospitalization duration in critically ill patients. PATIENTS AND METHODS: A retrospective analysis was made of patients admitted to our tertiary adult i̇ntensive Care Unit (ICU) between January 2015 and January 2016. Hemoglobin (Hb), white blood cell (WBC), lymphocyte and platelet counts were obtained from the complete blood count performed at the time of admission...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29759075/metabolic-profiles-in-community-acquired-pneumonia-developing-assessment-tools-for-disease-severity
#5
Pu Ning, Yali Zheng, Qiongzhen Luo, Xiaohui Liu, Yu Kang, Yan Zhang, Rongbao Zhang, Yu Xu, Donghong Yang, Wen Xi, Keqiang Wang, Yusheng Chen, Shuchang An, Zhancheng Gao
BACKGROUND: This study aimed to determine whether community-acquired pneumonia (CAP) had a metabolic profile and whether this profile can be used for disease severity assessment. METHODS: A total of 175 individuals including 119 CAP patients and 56 controls were enrolled and divided into two cohorts. Serum samples from a discovery cohort (n = 102, including 38 non-severe CAP, 30 severe CAP, and 34 age and sex-matched controls) were determined by untargeted ultra-high-performance liquid chromatography with tandem mass spectrometry (LC-MS/MS)-based metabolomics...
May 14, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29742956/rapid-muscle-loss-negatively-impacts-survival-in-critically-ill-patients-with-cirrhosis
#6
Sunmi Ju, Sun Mi Choi, Young Sik Park, Chang-Hoon Lee, Sang-Min Lee, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Jinwoo Lee
PURPOSE: To assess the impact of rapid muscle loss before admission to intensive care unit (ICU) in critically ill patients with cirrhosis. MATERIALS AND METHODS: Patients with cirrhosis who had undergone 2 or more recent computed tomography scans before admission to the medical ICU were included. Muscle cross-sectional area at the level of the third lumbar vertebra was quantified using OsiriX software. The rate of muscle mass change and skeletal muscle index (SMI) were also calculated...
January 1, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29742219/assessment-of-delirium-using-the-pre-deliric-model-in-an-intensive-care-unit-in-argentina
#7
Fernando Ariel Sosa, Javier Roberti, Margarita Tovar Franco, María Mercedes Kleinert, Agustina Risso Patrón, Javier Osatnik
OBJECTIVE: To describe the incidence of and risk factors for delirium in the intensive care unit of a tertiary care teaching hospital in Argentina and to conduct the first non-European study exploring the performance of the PREdiction of DELIRium in ICu patients (PRE-DELIRIC) model. METHODS: Prospective observational study in a 20-bed intensive care unit of a tertiary care teaching hospital in Buenos Aires, Argentina. The PRE-DELIRIC model was applied to 178 consecutive patients within 24 hours of admission to the intensive care unit; delirium was assessed with the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)...
March 2018: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/29741298/early-increase-of-vegf-a-is-associated-with-resolution-of-ventilator-associated-pneumonia-clinical-and-experimental-evidence
#8
Ioannis Strouvalis, Christina Routsi, Maria Adamopoulou, Maria Raftogiannis, George Renieris, Stylianos E Orfanos, Anastasia Kotanidou, Labros Sabracos, Evangelos J Giamarellos-Bourboulis
BACKGROUND AND OBJECTIVE: The role of vascular endothelial growth factor (VEGF)-A in the resolution of ventilator-associated pneumonia (VAP) was investigated in clinical and mouse pneumonia models. METHODS: VEGF-A was measured for seven consecutive days by an immunosorbent assay in sera of 82 patients with VAP and changes from baseline were correlated with the resolution of VAP. Experimental animals were challenged intratracheally with Pseudomonas aeruginosa. Mouse bronchoalveolar lavage (BAL) samples and segments of lung tissue were obtained at 24, 48 and 124 h after bacterial challenge...
May 9, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29740716/increase-in-intra-abdominal-pressure-during-airway-suctioning-induced-cough-after-a-successful-spontaneous-breathing-trial-is-associated-with-extubation-outcome
#9
Yasuhiro Norisue, Jun Kataoka, Yosuke Homma, Takaki Naito, Junpei Tsukuda, Kentaro Okamoto, Takeshi Kawaguchi, Lonny Ashworth, Shimada Yumiko, Yuiko Hoshina, Eiji Hiraoka, Shigeki Fujitani
BACKGROUND: A patient's ability to clear secretions and protect the airway with an effective cough is an important part of the pre-extubation evaluation. An increase in intra-abdominal pressure (IAP) is important in generating the flow rate necessary for a cough. This study investigated whether an increase from baseline in IAP during a coughing episode induced by routine pre-extubation airway suctioning is associated with extubation outcome after a successful spontaneous breathing trial (SBT)...
May 8, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29731648/a-retrospective-comparative-analysis-of-risk-factors-and-outcomes-in-carbapenem-susceptible-and-carbapenem-nonsusceptible-klebsiella-pneumoniae-bloodstream-infections-tigecycline-significantly-increases-the-mortality
#10
Tingting Xiao, Wei Yu, Tianshui Niu, Chen Huang, Yonghong Xiao
Background: Carbapenem-nonsusceptible Klebsiella pneumoniae (CnSKP) is rapidly emerging as a life-threatening nosocomial infection. The efficacy of tigecycline in the treatment of bloodstream infections (BSIs) remains controversial. Methods: Data from a total of 428 patients with carbapenem-susceptible Klebsiella pneumoniae (CSKP) and CnSKP BSIs were collected at a single center between January 2013 and December 2015. A three-part analysis was conducted to identify the risk factors associated with CnSKP, explore prognosis, and evaluate treatments...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29731386/characteristics-and-outcomes-of-do-not-resuscitate-patients-admitted-to-the-emergency-department-intensive-care-unit
#11
An-Yi Wang, Hon-Ping Ma, Wei-Fong Kao, Shin-Han Tsai, Cheng-Kuei Chang
BACKGROUND: Appropriate utilization of intensive care unit (ICU) beds are essential. Patients with critical illness who have do not resuscitate (DNR) have a reduced priority of intensive care. However, the possibility of recovery/survival is ambiguous and multifactorial. OBJECTIVE: To deliberate the characteristics and outcomes of critical illness in patients with prior DNR who were admitted to the emergency department (ED)-ICU. METHOD: This was a retrospective cohort study conducted between April 2015 and November 2015 in a university-based hospital...
May 3, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29731384/a-multicenter-study-on-clinical-characteristics-of-acinetobacter-bacteremia-in-patients-with-liver-cirrhosis
#12
Chang-Pan Liu, Tsung-Ta Chiang, Yuag-Meng Liu, Shu-Chen Kuo, Ya-Sung Yang, Yi-Tzu Lee, Te-Li Chen, Shou-Chuan Shih
BACKGROUND: Clinical characteristics and risk factors for mortality of Acinetobacter bacteremia in cirrhotic patients have not been investigated. METHODS: Acinetobacter bacteremia cases from four medical centers were collected from 2009 to 2014, to compare between patients with and without liver cirrhosis. Risk factors for mortality of Acinetobacter bacteremia among cirrhotic patients were identified using multivariate logistic regression. RESULTS: Among the patients with Acinetobacter bacteremia, 72 had liver cirrhosis and 816 had not...
April 25, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29726670/-clinical-significance-and-risk-factors-for-multidrug-resistant-enterobacteriaceae-colonization
#13
A Padilla-Serrano, J J Serrano-Castañeda, R Carranza-González, M P García-Bonillo
OBJECTIVE: To identify the main risk factors of rectal colonization by multidrug resistant Enterobacteriaceae (MRE), and their clinical impact. METHODS: An observational, prospective cohort study was carried out, between April 2016 and June 2017, where every Monday of each week rectal samples were taken from all the patients admitted at that moment in the Intensive Care Unit. We performed a descriptive analysis of all the variables collected during the study and a multivariate logistic regression analysis to determine the independent association of carriers of MRE against non-carriers and several possible risk factors...
May 4, 2018: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/29726446/estimation-of-the-accuracy-of-prognostic-scores-for-the-treatment-of-children-with-severe-trauma-in-a-specialized-trauma-hospital
#14
Irina V Vasilyeva, Sergey L Shvirev, Tatyana V Zarubina, Olga V Karaseva, Alexander S Samoylov, Yuri D Udalov
The aim of the present work was to study the validity and prognostic accuracy of scores for assessing the severity of the condition in children with severe trauma, located in the Department of Anesthesiology and Resuscitation in the Clinical and Research Institute of Urgent Pediatric Surgery and Trauma. The prospective study was conducted using clinical and physiological data collected at the admission and during the first 24 hours of hospitalization from 474 patients. The validity and prognostic accuracy of prognostic scores were assessed by determining their discrimination and calibration ability...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29725778/skin-microcirculatory-reactivity-assessed-using-a-thermal-challenge-is-decreased-in-patients-with-circulatory-shock-and-associated-with-outcome
#15
Diego Orbegozo, Wasineenart Mongkolpun, Gianni Stringari, Nikolaos Markou, Jacques Creteur, Jean-Louis Vincent, Daniel De Backer
BACKGROUND: Shock states are characterized by impaired tissue perfusion and microcirculatory alterations, which are directly related to outcome. Skin perfusion can be noninvasively evaluated using skin laser Doppler (SLD), which, when coupled with a local thermal challenge, may provide a measure of microcirculatory reactivity. We hypothesized that this microvascular reactivity would be impaired in patients with circulatory shock and would be a marker of severity. METHODS: We first evaluated skin blood flow (SBF) using SLD on the forearm and on the palm in 18 healthy volunteers to select the site with maximal response...
May 3, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29723201/performance-on-the-apache-ii-saps-ii-sofa-and-the-ohca-score-of-post-cardiac-arrest-patients-treated-with-therapeutic-hypothermia
#16
Jea Yeon Choi, Jae Ho Jang, Yong Su Lim, Jee Yong Jang, Gun Lee, Hyuk Jun Yang, Jin Seong Cho, Sung Youl Hyun
OBJECTIVE: This study assessed the ability of the Acute Physiologic and Chronic Health Evaluation (APACHE) II score, Simplified Acute Physiology Score (SAPS) II, Sequential Organ Failure Assessment (SOFA) score, and out-of-hospital cardiac arrest (OHCA) score to predict the outcome of OHCA patients who underwent therapeutic hypothermia (TH). METHODS: This study included OHCA patients treated with TH between January 2010 and December 2013. The APACHE II score, SAPS II, and SOFA score were calculated at the time of admission and 24 h and 48 h after intensive care unit admission...
2018: PloS One
https://www.readbyqxmd.com/read/29722334/antibiotics-de-escalation-in-the-treatment-of-ventilator-associated-pneumonia-in-trauma-patients-a-retrospective-study-on-propensity-score-matching-method
#17
Hu Li, Chun-Hui Yang, Li-Ou Huang, Yu-Hui Cui, Dan Xu, Chun-Rong Wu, Jian-Guo Tang
Background: Antimicrobial de-escalation refers to starting the antimicrobial treatment with broad-spectrum antibiotics, followed by narrowing the drug spectrum according to culture results. The present study evaluated the effect of de-escalation on ventilator-associated pneumonia (VAP) in trauma patients. Methods: This retrospective study was conducted on trauma patients with VAP, who received de-escalation therapy (de-escalation group) or non-de-escalation therapy (non-de-escalation group)...
May 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29719845/the-efficacy-of-glasgow-coma-scale-gcs-score-and-acute-physiology-and-chronic-health-evaluation-apache-ii-for-predicting-hospital-mortality-of-icu-patients-with-acute-traumatic-brain-injury
#18
Amir Nik, Mohammad Sobhan Sheikh Andalibi, Mohammad Reza Ehsaei, Ahmadreza Zarifian, Ehsan Ghayoor Karimiani, Gholamreza Bahadoorkhan
Objective: To compare the efficacy and functional outcome of Glasgow Coma Scale (GCS) score with that of Acute Physiology and Chronic Health Evaluation Score II (APACHE II) in patients with multiple trauma admitted to the ICU. Methods: This cross-sectional study included 125 patients with traumatic brain injury associated with systemic trauma admitted to the ICU of Shahid Kamyab Hospital, Mashhad, between September 2015 and December 2016. On the day of admission, data were collected from each patient to calculate GCS and APACHE II scores...
April 2018: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/29709560/contributing-factors-to-mortality-rates-of-pulmonary-tuberculosis-in-intensive-care-units
#19
Dursun Tatar, Gunes Senol, Cenk Kirakli, Ozlem Edipoglu, Pinar Cimen
BACKGROUND: Tuberculosis (TB) remains an important health problem worldwide. TB patients sometimes require intensive care unit (ICU) treatment. The aim of this study is to establish special features and mortality rates of pulmonary TB patients in ICUs and identify the factors contributing to ICU mortality. METHODS: Medical records of adult patients (>18 years) with a diagnosis of TB who were admitted to the ICU of a referral hospital for chest diseases between 2004 and 2010 were reviewed retrospectively...
April 27, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29696116/comparison-of-glasgow-coma-scale-full-outline-of-unresponsiveness-and-acute-physiology-and-chronic-health-evaluation-in-prediction-of-mortality-rate-among-patients-with-traumatic-brain-injury-admitted-to-intensive-care-unit
#20
Seyed Hossein Hosseini, Mitra Ayyasi, Hooshang Akbari, Mohammad Ali Heidari Gorji
Background: Traumatic brain injury (TBI) is a common cause of mortality and disability worldwide. Choosing an appropriate diagnostic tool is critical in early stage for appropriate decision about primary diagnosis, medical care and prognosis. Objectives: This study aimed to compare the Glasgow coma scale (GCS), full outline of unresponsiveness (FOUR) and acute physiology and chronic health evaluation (APACHE II) with respect to prediction of the mortality rate of patients with TBI admitted to intensive care unit...
October 2017: Anesthesiology and Pain Medicine
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