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https://www.readbyqxmd.com/read/29777555/impact-of-nicu-oral-feeding-on-neuropsychomotor-outcomes-at-9-months-of-corrected-age-in-chinese-low-birth-weight-preterm-infants-a-retrospective-study
#1
Wenwen Ding, Lijin Zhao, Nan Sheng, Jiali Ma, Ying Zhang
AIMS AND OBJECTIVES: To examine the changes in neuropsychomotor development and investigate the effect of feeding progression in Neonatal Intensive Care Unit (NICU) on neuropsychomotor outcomes in low-birth-weight preterm infants within 9 months of corrected age. BACKGROUND: Low-birth-weight (LBW) preterm infants (<37 weeks of gestation and birth weight < 2500 g) are at a high risk for neuropsychomotor development delay. Therefore, exploring NICU practices related to neuropsychomotor development is important...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29776967/multicentre-study-of-maternal-and-neonatal-outcomes-in-individuals-with-prader-willi-syndrome
#2
Preeti Singh, Ranim Mahmoud, June-Anne Gold, Jennifer L Miller, Elizabeth Roof, Roy Tamura, Elisabeth Dykens, Merlin G Butler, Dan J Driscoll, Virginia Kimonis
INTRODUCTION: Prader-Willi syndrome (PWS) is a complex genetic disorder associated with three different genetic subtypes: deletion of the paternal copy of 15q11-q13, maternal UPD for chromosome 15 and imprinting defect. Patients are typically diagnosed because of neonatal hypotonia, dysmorphism and feeding difficulties; however, data on the prenatal features of PWS are limited. OBJECTIVE: The aim of the study was to identify and compare frequencies of prenatal and neonatal clinical features of PWS among the three genetic subtypes...
May 18, 2018: Journal of Medical Genetics
https://www.readbyqxmd.com/read/29770842/clinical-features-and-practice-patterns-of-gastroschisis-a-retrospective-analysis-using-a-japanese-national-inpatient-database
#3
Michimasa Fujiogi, Nobuaki Michihata, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Jun Fujishiro
PURPOSE: The number of infants with gastroschisis is increasing worldwide, but advances in neonatal intensive care and parenteral nutrition have reduced gastroschisis mortality. Recent clinical data on gastroschisis are often from Western nations. This study aimed to examine clinical features and practice patterns of gastroschisis in Japan. METHODS: We examined treatment options, outcomes, and discharge status among inpatients with simple gastroschisis (SG) and complex gastroschisis (CG), 2010-2016, using a national inpatient database in Japan...
May 16, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29769176/using-feeding-to-reduce-pain-during-vaccination-of-formula-fed-infants-a-randomised-controlled-trial
#4
Netty G P Bos-Veneman, Marrit Otter, Sijmen A Reijneveld
OBJECTIVES: To assess the effectiveness and potential side effects of formula feeding to reduce pain during vaccination among infants. STUDY DESIGN: In the setting of well-baby clinics we recruited a community-based sample of full-term born infants who were already formula fed by the choice of the parents (n=48, aged 4-10 weeks) and received their first DTaP-IPV-HepB-Hib and pneumococcal vaccinations and randomised them into two groups. To evaluate pain experienced during vaccination we compared infants who drank formula feeding before, during and after vaccination with infants who did not...
May 16, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29767696/clinical-outcomes-related-to-the-gastrointestinal-trophic-effects-of-erythropoietin-in-preterm-neonates-a-systematic-review-and-meta-analysis
#5
Anitha Ananthan, Haribalakrishna Balasubramanian, Shripada Rao, Sanjay Patole
Erythropoietin (EPO) plays an important role in the development and maturation of the gastrointestinal tract. Recombinant EPO (rEPO) has been used to prevent anemia of prematurity. The gastrointestinal trophic effects of EPO may reduce feeding intolerance and necrotizing enterocolitis (NEC) in preterm neonates. The aim of this systematic review of randomized controlled trials (RCTs) was to evaluate the effects of rEPO on clinical outcomes such as feeding intolerance, stage II or higher NEC, any stage NEC, sepsis, retinopathy of prematurity, and bronchopulmonary dysplasia in preterm neonates...
May 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29756373/do-feeding-practices-during-transfusion-influence-the-risk-of-developing-necrotising-enterocolitis-in-preterm-infants
#6
Cathie Hilditch, Amy Keir
Our evidence-based review set out to answer the clinical question 'In a preterm infant (patient) with anaemia of prematurity, do feeding practices (intervention) during blood transfusion reduce the risk of developing transfusion-associated necrotising enterocolitis (outcome)'? We found limited evidence that withholding feeding during red blood cell transfusion in preterm infants may reduce the risk of development of transfusion-associated necrotising enterocolitis. As clinical equipoise seemingly exists, it seems reasonable for individual units to make their own decisions regarding whether to withhold or continue enteral feeds during red blood cell transfusion until further evidence is available...
May 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29754879/congenital-pyloric-atresia-nine-new-cases-single-center-experience-of-the-long-term-follow-up-and-the-lessons-learnt-over-a-decade
#7
Monal Kansra, V Shankar Raman, Kamal Kishore, Sanat Khanna, Bipin Puri, Abhishek Sharma
BACKGROUND: Congenital pyloric atresia (CPA) is a rare anomaly with an incidence of 1 in 100,000 live births. Depending on the type of anomaly patients can either present in the neonatal period or later in life with subtle nonspecific signs and symptoms. We present our institute's experience in handling these cases over the last decade and highlight lessons learnt. MATERIALS AND METHODS: We retrospectively reviewed records of patients diagnosed with CPA and managed at our centre between Jan 2006 to June 2016...
April 14, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29754124/predictors-of-postoperative-rehabilitation-therapy-following-congenital-heart-surgery
#8
Ana Ubeda Tikkanen, Meena Nathan, Lynn A Sleeper, Marisa Flavin, Ana Lewis, Donna Nimec, John E Mayer, Pedro Del Nido
BACKGROUND: Patients with congenital heart disease are at risk of motor, cognitive, speech, and feeding difficulties after cardiac surgery. Rehabilitation therapy could improve functional outcomes in this population if applied in the acute postcardiac surgical in-hospital stay. However, information on the types of acute postcardiac surgery therapy needs in children is scarce. Our goal was to describe rehabilitation therapy following congenital heart surgery and pre/intraoperative factors associated with need for therapy...
May 12, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29746271/factor-structure-and-psychometric-properties-of-the-neonatal-eating-assessment-tool-bottle-feeding-neoeat-bottle-feeding
#9
Britt Frisk Pados, Suzanne M Thoyre, Hayley H Estrem, Jinhee Park, Cara McComish
BACKGROUND: Feeding difficulties are common in infancy. There are currently no valid and reliable parent-report measures to assess bottle-feeding in infants younger than 7 months. The Neonatal Eating Assessment Tool (NeoEAT)-Bottle-feeding has been developed and content validated. PURPOSE: To determine the factor structure and psychometric properties of the NeoEAT-Bottle-feeding. METHODS: Parents of bottle-feeding infants younger than 7 months were invited to participate...
May 9, 2018: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/29746151/determinants-of-successful-direct-breastfeeding-at-hospital-discharge-in-high-risk-premature-infants
#10
Lara Casey, Sandra Fucile, Kimberly E Dow
BACKGROUND: Despite a mother's intention to breastfeed, there are many barriers to feeding preterm infants that decrease breastfeeding rates. OBJECTIVE: The objective of this research was to determine factors associated with successful direct breastfeeding (DBF) of the preterm infant at hospital discharge. MATERIALS AND METHODS: A retrospective chart review of 69 preterm (<34 weeks' gestational age) infants in the neonatal intensive care unit, whose mothers intended to breastfeed, was conducted...
May 10, 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29742464/gastrointestinal-microbiota-and-mucosal-immune-gene-expression-in-neonatal-pigs-reared-in-a-cross-fostering-model
#11
Nidia Maradiaga, Brian Aldridge, Mohamed Zeineldin, James Lowe
Cross fostering is employed to equalize the number of piglet between litters ensuring colostrum intake for their survival and growth. However, little is known about the impact of cross fostering on the intestinal microbiota and mucosal immune gene expression of the neonatal pig. The objective of this study was to determine the influence of maternal microbial communities on the gastrointestinal (GI) microbiota and mucosal immune gene expression in young pigs reared in a cross-fostering model. Piglets were given high quality colostrum from birth dam or foster dam upon birth...
May 6, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29740193/reducing-time-to-initiation-and-advancement-of-enteral-feeding-in-an-all-referral-neonatal-intensive-care-unit
#12
Sarah U Morton, Mandy B Belfort, Prerna S Kahlon, Sara Hajizadeh Barfjani, Coral Rudie, Emily Hashim, Anne Hansen, Susanna Y Huh
OBJECTIVE: Decrease time to enteral feeding initiation and advancement. STUDY DESIGN: In our all-referral neonatal intensive care unit, we developed an evidence-based guideline addressing feeding initiation and advancement. During 6 months before and 7 months after guideline implementation, we measured time to initiate feeding, time to 100 ml/kg/day of feeding, gastric residual measurement frequency, and incidence of necrotizing enterocolitis (balancing measure)...
May 8, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29733417/1h-nuclear-magnetic-resonance-based-plasma-metabolomics-provides-another-perspective-of-response-mechanisms-of-newborn-calves-upon-the-first-colostrum-feeding
#13
Y S Guo, J Z Tao
The first meal of a neonatal calf after birth is crucial for survival and health. Blood IgG levels remarkably increase in neonatal calves after the first colostrum feeding. However, there is little comprehensive information on blood small-molecule metabolites in neonatal calves at that time. In this study, the changes in plasma metabolites of neonatal calves after the initial colostrum feeding were first examined with comprehensive 1H nuclear magnetic resonance (NMR). Sixteen plasma samples obtained from 8 calves before and after feeding were analyzed with 1H NMR...
May 4, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29733102/breastfeeding-and-risk-for-ceasing-in-mothers-of-preterm-infants-long-term-follow-up
#14
Jenny Ericson, Mats Eriksson, Pat Hoddinott, Lena Hellström-Westas, Renée Flacking
Breastfeeding is challenging for mothers of preterm infants. The aim of this paper is to describe risk factors for ceasing breastfeeding and methods of feeding until 12 months postnatal age in mothers who breastfed their preterm infants at discharge from neonatal intensive care units (NICUs). The data come from a randomised controlled trial, which evaluated the effectiveness on exclusive breastfeeding at 8 weeks of proactive telephone support compared with reactive support offered to mothers of preterm infants following discharge from NICU...
May 7, 2018: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29731340/cryptococcus-laurentii-fungemia-in-a-low-birth-weight-preterm-neonate-india
#15
Minakshi Gupta, Asit K Mishra, Santosh K Singh
In the last few years, Cryptococcus laurentii infections have increased, particularly in immunocompromised patients. Here we report the first case of C. laurentii fungemia in low birth weight preterm infant from India. A preterm neonate was admitted for feeding intolerance and respiratory distress. Blood culture ascertained the causative organism as C. laurentii. The isolated strain was found susceptible to amphotericin B and the patient recovered following the administration of amphotericin B (5mg/kg body weight) for 8days...
April 30, 2018: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/29728917/short-and-long-term-effects-of-leucine-and-branched-chain-amino-acid-supplementation-of-a-protein-and-energy-reduced-diet-on-muscle-protein-metabolism-in-neonatal-pigs
#16
Rodrigo Manjarín, Daniel A Columbus, Jessica Solis, Adriana D Hernandez-García, Agus Suryawan, Hanh V Nguyen, Molly M McGuckin, Rafael T Jimenez, Marta L Fiorotto, Teresa A Davis
The objective of this study was to determine if enteral leucine or branched-chain amino acid (BCAA) supplementation increases muscle protein synthesis in neonates who consume less than their protein and energy requirements, and whether this increase is mediated via the upregulation of the mechanistic target of rapamycin complex 1 (mTORC1) pathway or the decrease in muscle protein degradation signaling. Neonatal pigs were fed milk replacement diets containing reduced energy and protein (R), R supplemented with BCAA (RBCAA), R supplemented with leucine (RL), or complete protein and energy (CON) at 4-h intervals for 9 (n = 24) or 21 days (n = 22)...
May 4, 2018: Amino Acids
https://www.readbyqxmd.com/read/29726081/liver-transplantation-for-neonatal-onset-citrullinemia
#17
Roshni Vara, Anil Dhawan, Maesha Deheragoda, Stephanie Grünewald, Germaine Pierre, Nigel D Heaton, Hector Vilca-Melendez, Nedim Hadžić
Citrullinemia or ASS deficiency in its classical form presents in the neonatal period with poor feeding, hyperammonemia, encephalopathy, seizures, and if untreated can be fatal. Despite advances in medical therapy, neurocognitive outcomes remain suboptimal. LT has emerged as a potential management option. A retrospective single-center review identified 7 children with a median age of 1.1 years (range, 0.6-5.8) at referral. Five children presented clinically, and 2 were treated prospectively from birth due to positive family history...
May 3, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29723880/factors-known-to-influence-the-development-of-necrotizing-enterocolitis-to-modify-expression-and-activity-of-intestinal-alkaline-phosphatase-in-a-newborn-neonatal-rat-model
#18
Rebecca Maria Rentea, Matthea J Rentea, Ben Biesterveld, Jennifer L Liedel, David M Gourlay
INTRODUCTION:  Prematurity, formula feeding, and early weaning strongly influence enterocyte differentiation. Intestinal alkaline phosphatase (IAP), an endogenous protein expressed in the intestines, is one enzyme that is affected by these factors. IAP supplementation decreases the severity of necrotizing enterocolitis (NEC) injury. We, therefore, hypothesized that prematurity predisposes this population to NEC due to IAP deficiency and investigated IAP expression and function in a neonatal rat model...
May 3, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29722867/evaluating-the-quality-of-the-processes-of-care-and-clinical-outcomes-of-premature-newborns-admitted-to-neonatal-intensive-care-units-in-mexico
#19
Svetlana V Doubova, Heladia Josefa-García, Irma Alejandra Coronado-Zarco, Sandra Carrera-Muiños, Guadalupe Cordero-Gonzalez, Leonardo Cruz-Reynoso, Leovigildo Mateos-Sanchez, Ana Jesica Maya-García, Ricardo Pérez-Cuevas
Objectives: To develop quality of care (QoC) indicators, evaluate the quality of the processes of care (QPC) and clinical outcomes, and analyze the association between the QPC and severe clinical outcomes of preterm newborns admitted to neonatal intensive care units (NICUs). Design: Mixed methods approach: (1) development of QoC indicators via modified RAND/UCLA method; (2) cross-sectional study of QoC evaluation and (3) multiple logistic regression analysis to ascertain the association between the QPC and severe clinical outcomes...
April 4, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29721538/upper-airway-obstruction-in-neonates-does-sleep-exacerbate-symptoms
#20
Tyler Van Heest, Bridget Ebert, Brianne Barnett Roby, James Sidman
Objective: Describe the factors that exacerbate upper airway obstructions (UAOs) in neonates. Study Design: Retrospective chart review. Setting: Pediatric tertiary care hospital. Subjects and Methods: All neonates hospitalized between 1/1/2010 and 12/31/2014 diagnosed with either: 1) laryngomalacia, 2) Pierre Robin sequence, or 3) vocal cord paralysis were included in this study. Patient charts were reviewed to determine factors that exacerbated symptoms of airway obstruction...
April 2018: Laryngoscope Investigative Otolaryngology
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