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https://www.readbyqxmd.com/read/28820922/a-self-assembling-peptide-gel-as-a-vitreous-substitute-a-rabbit-study
#1
Koji Uesugi, Hirokazu Sakaguchi, Yasutaka Hayashida, Ryuhei Hayashi, Koichi Baba, Yuya Suganuma, Hidenori Yokoi, Motokazu Tsujikawa, Kohji Nishida
Purpose: To evaluate a self-assembling peptide gel as a potential vitreous substitute. Methods: PanaceaGel SPG-178, a self-assembling peptide gel, was diluted with distilled water and a balanced salt solution to achieve a final peptide concentration of 0.1%. The gel's refractive index, visible light transmission rate, and rheologic properties were investigated. The gel's biocompatibility was evaluated by examining the cellular viability (live and dead staining) and proliferation rate (alamarBlue assay)...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28818397/life-cycle-inventory-and-mass-balance-of-municipal-food-waste-management-systems-decision-support-methods-beyond-the-waste-hierarchy
#2
Joel Edwards, Maazuza Othman, Enda Crossin, Stewart Burn
When assessing the environmental and human health impact of a municipal food waste (FW) management system waste managers typically rely on the principles of the waste hierarchy; using metrics such as the mass or rate of waste that is 'prepared for recycling,' 'recovered for energy,' or 'sent to landfill.' These metrics measure the collection and sorting efficiency of a waste system but are incapable of determining the efficiency of a system to turn waste into a valuable resource. In this study a life cycle approach was employed using a system boundary that includes the entire waste service provision from collection to safe end-use or disposal...
August 14, 2017: Waste Management
https://www.readbyqxmd.com/read/28817639/impacts-of-forest-restoration-on-water-yield-a-systematic-review
#3
Solange Filoso, Maíra Ometto Bezerra, Katherine C B Weiss, Margaret A Palmer
BACKGROUND: Enhancing water provision services is a common target in forest restoration projects worldwide due to growing concerns over freshwater scarcity. However, whether or not forest cover expansion or restoration can improve water provision services is still unclear and highly disputed. PURPOSE: The goal of this review is to provide a balanced and impartial assessment of the impacts of forest restoration and forest cover expansion on water yields as informed by the scientific literature...
2017: PloS One
https://www.readbyqxmd.com/read/28816060/the-broad-spectrum-antimicrobial-potential-of-mn-co-4-s2cnme-ch2co2h-a-water-soluble-co-releasing-molecule-corm-401-intracellular-accumulation-transcriptomic-and-statistical-analyses-and-membrane-polarization
#4
Lauren Katie Wareham, Samantha McLean, Ronald Begg, Namrata Rana, Salar Ali, John J Kendall, Guido Sanguinetti, Brian E Mann, Robert K Poole
AIMS: Carbon monoxide (CO)-releasing molecules (CORMs) are candidates for animal and antimicrobial therapeutics. We aimed to probe the antimicrobial potential of a novel manganese CORM. RESULTS: [Mn(CO)4S2CNMe(CH2CO2H)], CORM-401, inhibits growth of Escherichia coli and several antibiotic-resistant clinical pathogens. CORM-401 releases CO that binds oxidases in vivo but is an ineffective respiratory inhibitor. Extensive CORM accumulation (assayed as intracellular manganese) accompanies antimicrobial activity...
August 17, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28813467/meat-consumption-reduction-in-italian-regions-health-co-benefits-and-decreases-in-ghg-emissions
#5
Sara Farchi, Manuela De Sario, Enrica Lapucci, Marina Davoli, Paola Michelozzi
INTRODUCTION: Animal agriculture has exponentially grown in recent decades in response to the rise in global demand for meat, even in countries like Italy that traditionally eat a Mediterranean, plant-based diet. Globalization related dietary changes are contributing to the epidemic of non-communicable diseases and to the global climate crisis, and are associated with huge carbon and water footprints. The objective of the study is to assess inequalities in health impacts and in attributable greenhouse gases-GHG emissions in Italy by hypothesizing different scenarios of reduction in red and processed meat consumption towards healthier consumption patterns more compliant with the recommendations of the Mediterranean food pyramid...
2017: PloS One
https://www.readbyqxmd.com/read/28808011/behavioral-responses-to-annual-temperature-variation-alter-the-dominant-energy-pathway-growth-and-condition-of-a-cold-water-predator
#6
Matthew M Guzzo, Paul J Blanchfield, Michael D Rennie
There is a pressing need to understand how ecosystems will respond to climate change. To date, no long-term empirical studies have confirmed that fish populations exhibit adaptive foraging behavior in response to temperature variation and the potential implications this has on fitness. Here, we use an unparalleled 11-y acoustic telemetry, stable isotope, and mark-recapture dataset to test if a population of lake trout (Salvelinus namaycush), a cold-water stenotherm, adjusted its use of habitat and energy sources in response to annual variations in lake temperatures during the open-water season and how these changes translated to the growth and condition of individual fish...
August 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28803645/liquid-chromatography-quadrupole-orbitrap-mass-spectrometry-method-for-selected-pharmaceuticals-in-water-samples
#7
Jalal T Althakafy, Chadin Kulsing, Michael R Grace, Philip J Marriott
This study developed an analytical approach for sub-ppb level detection and confirmation of 13 pharmaceuticals and personal care products (PPCPs) in water samples using ultra high pressure liquid chromatography hyphenated with a quadrupole Orbitrap mass spectrometer (UHPLC- Q-Orbitrap-MS). Sample preparation was performed by using solid phase extraction (SPE) employing hydrophilic-lipophilic balance cartridges, with elution of sorbed analytes using methanol. Acceptable automatic gain control (AGC) target and maximum injection time (IT) were 1×10(6) and 200ms, respectively, resulting in a mass accuracy <2ppm...
August 3, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28803205/water-footprint-assessment-for-crop-production-based-on-field-measurements-a-case-study-of-irrigated-paddy-rice-in-east-china
#8
Cao Xinchun, Wu Mengyang, Shu Rui, Zhuo La, Chen Dan, Shao Guangcheng, Guo Xiangping, Wang Weiguang, Tang Shuhai
Water footprint (WF) is a comprehensive measure of water consumption by human activities and can be used to assess the impact on both water volume and quality. This study aims to explore the feasibility of evaluating green, blue and grey WFs of crop production based on field measurements. The irrigated paddy rice grown in three different experimental sites in different typical irrigation districts in Huai'an, East China over 2011 to 2014 was taken as study case. With fixed irrigation and fertilization, on the basis of measuring field water and fertilizer balance at daily step, we calculated WF of crop production under different test treatments...
August 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28803200/ecological-state-of-a-mountain-river-before-and-after-a-large-flood-implications-for-river-status-assessment
#9
Hanna Hajdukiewicz, Bartłomiej Wyżga, Antoni Amirowicz, Paweł Oglęcki, Artur Radecki-Pawlik, Joanna Zawiejska, Paweł Mikuś
Assessment of the ecological status of rivers is key to monitoring the achievement of the environmental goal of the EU Water Framework Directive and the success of restoration projects. In summer of 2009 and 2010, repeated assessments of physical habitat conditions and of fish and benthic invertebrate communities were performed at low-flow conditions in 10 unmanaged and 10 channelized cross-sections of the Biała River, Polish Carpathians. Between the two surveys, an 80-year flood occurred, significantly affecting habitat characteristics and river communities...
August 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28801267/primum-non-nocere-the-effects-of-sodium-hypochlorite-on-dentin-as-used-in-endodontics
#10
Li-Sha Gu, Xue-Qing Huang, Brandon Griffin, Brian R Bergeron, David H Pashley, Li-Na Niu, Franklin R Tay
The medical literature is replete with the maxim 'primum non nocere', cautioning health care providers to avoid doing any harm to human subjects in their delivery of medical care. Sodium hypochlorite (NaOCl) is a well-established irrigant for root canal treatment because of its antimicrobial and organic tissue remnant dissolution capability. However, little is known about the deleterious effect of this strong oxidizing agent on the integrity of human mineralized dentin. Iatrogenically-induced loss of dentin integrity may precipitate post-treatment root fracture and has potential medico-legal complications...
August 8, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28801081/effects-of-therapeutic-touch-on-healing-of-the-skin-in-rats
#11
André Luiz Thomaz de Souza, David Patrick Carvalho Rosa, Bruno Anjos Blanco, Patrícia Passaglia, Angelita Maria Stabile
CONTEXT: Therapeutic touch is a complementary treatment directed toward the balance of the energy field surrounding living beings. OBJECTIVE: This study's aim was to investigate the effect of therapeutic touch on wound area contraction and fibroblast proliferation in rat skin. DESIGN: This study was conducted using 24 male Wistar rats with dorsal wounds of diameter 8mm. The rats were divided into the following two groups: a control group: in this, the wounds were sanitized with filtered water and neutral-pH soap and a treatment group: in this, the wounds were sanitized as in the control group but the rats also underwent to daily sessions of therapeutic touch...
July 1, 2017: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/28800549/simultaneous-determination-of-bentazone-and-its-metabolites-in-postmortem-whole-blood-using-liquid-chromatography-tandem-mass-spectrometry
#12
Byungsuk Cho, Suncheun Kim, Sangwhan In, Sanggil Choe
A liquid chromatography-tandem mass spectrometry method with solid-phase extraction (SPE) was developed and validated for the detection and quantitation of bentazone and its two hydroxylated metabolites, 6-hydroxybentazone and 8-hydroxybentazone, in postmortem blood. Sample cleanup was performed using a hydrophilic-lipophilic balanced (HLB) SPE cartridge and then separated on a C18 LC column using a gradient elution of 0.1% formic acid in distilled water and 0.1% formic acid in methanol. The identification of bentazone and its hydroxylated metabolites was performed using tandem mass spectrometry with electrospray ionization in negative ion mode with selective reaction monitoring...
July 29, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28800518/the-implications-of-drought-and-water-conservation-on-the-reuse-of-municipal-wastewater-recognizing-impacts-and-identifying-mitigation-possibilities
#13
Quynh K Tran, David Jassby, Kurt A Schwabe
As water agencies continue to investigate opportunities to increase resilience and local water supply reliability in the face of drought and rising water scarcity, water conservation strategies and the reuse of treated municipal wastewater are garnering significant attention and adoption. Yet a simple water balance thought experiment illustrates that drought, and the conservation strategies that are often enacted in response to it, both likely limit the role reuse may play in improving local water supply reliability...
July 27, 2017: Water Research
https://www.readbyqxmd.com/read/28799860/mutations-in-leptin-lep-gene-are-associated-with-carcass-and-meat-quality-traits-in-crossbreed-rabbits
#14
Lukasz Migdal, Konrad Koziol, Sylwia Palka, Wladyslaw Migdal, Tomasz Zabek, Agnieszka Otwinowska-Mindur, Anna Migdal, Michal Kmiecik, Dorota Maj, Jozef Bieniek
Leptin is a hormone synthesized and secreted primarily in adipose cells that help to regulate energy balance. This study examined the associations of single nucleotide polymorphisms in the rabbit leptin gene with growth traits, slaughter traits and physicochemical parameters of New Zealand White (NZW) and Belgian Giant Grey (BGG) crossbreed rabbits. In total, 320 crossbreed animals were genotyped for polymorphisms within exon 2-g.16081633T>C, intron 1_2-g.16081420C>T, and within UTR-g.16079636C>G for association analysis...
August 11, 2017: Animal Biotechnology
https://www.readbyqxmd.com/read/28799245/when-and-where-to-move-dynamic-occupancy-models-explain-the-range-dynamics-of-a-food-nomadic-bird-under-climate-and-land-cover-change
#15
Riddhika Kalle, Tharmalingam Ramesh, Colleen T Downs
Globally, long-term research is critical to monitor the responses of tropical species to climate and land cover change at the range scale. Citizen science surveys can reveal the long-term persistence of poorly known nomadic tropical birds occupying fragmented forest patches. We applied dynamic occupancy models to 13 years (2002-2014) of citizen science driven presence/absence data on Cape parrot (Poicephalus robustus), a food nomadic bird endemic to South Africa. We modelled its underlying range dynamics as a function of resource distribution, and change in climate and land cover through the estimation of colonization and extinction patterns...
August 11, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28799126/hydration-status-drug-interactions-and-determinants-in-a-spanish-elderly-population-a-pilot-study
#16
A M Puga, T Partearroyo, G Varela-Moreiras
Proper hydration is essential to maintain optimal health and well-being at all stages of life, especially for the elderly. Side effects of certain drugs that affect hydration status may compromise the health of the ancients, who also constitute the most vulnerable group. No studies have been carried out, to our knowledge, at the intersection of drugs and hydration status. Our study aimed to evaluate the effects of chronic use of certain drugs (diuretics, corticoids and metformin) in the hydration status of the elderly...
August 10, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28799050/environmental-building-policy-by-the-use-of-microalgae-and-decreasing-of-risks-for-canadian-oil-sand-sector-development
#17
Armen B Avagyan
Environmental building recommendations aimed towards new environmental policies and management-changing decisions which as example demonstrated in consideration of the problems of Canadian oil sands operators. For the implementation of the circular economic strategy, we use an in-depth analysis of reported environmental after-consequence on all stages of the production process. The study addressed the promotion of innovative solutions for greenhouse gas emission, waste mitigation, and risk of falling in oil prices for operators of oil sands with creating market opportunities...
August 10, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28797479/paralysis-and-heart-failure-precede-ion-balance-disruption-in-heat-stressed-european-green-crabs
#18
Lisa B Jørgensen, Johannes Overgaard, Heath A MacMillan
Acute exposure of ectotherms to critically high temperatures causes injury and death, and this mortality has been associated with a number of physiological perturbations including impaired oxygen transport, loss of ion and water homeostasis, and neuronal failure. It is difficult to discern which of these factors, if any, is the proximate cause of heat injury because, for example, loss of ion homeostasis can impair neuromuscular function (including cardiac function), and conversely impaired oxygen transport reduces ATP supply and can thus reduce ion transport capacity...
August 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28797478/heat-stress-is-associated-with-disruption-of-ion-balance-in-the-migratory-locust-locusta-migratoria
#19
James D B O'Sullivan, Heath A MacMillan, Johannes Overgaard
Thermal tolerance is important in determining the spatial and temporal distributions of insects but the mechanisms which determine upper thermal limits remain poorly understood. In terrestrial insects heat tolerance is unlikely to be limited by oxygen supply but in some arthropods, heat stress has been shown to cause haemolymph hyperkalaemia which is known to have detrimental effects on neuromuscular excitability. It is however unresolved if heat-induced hyperkalemia is the cause or the result of cellular heat injury...
August 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28796300/apelin-apj-system-a-novel-potential-therapy-target-for-kidney-disease
#20
REVIEW
Zhen Huang, Lele Wu, Linxi Chen
Apelin is an endogenous ligand of seven-transmembrane G protein-coupled receptor APJ. Apelin and APJ are distributed in various tissues, including the heart, lung, kidney, and even in tumor tissues. Studies show that apelin mRNA is highly expressed in the inner stripe of kidney outer medulla, which plays an important role in process of water and sodium balance. Additionally, more studies also indicate that apelin/APJ system exerts a broad range of activities in kidney. Therefore, we review the role of apelin/APJ system in kidney diseases such as renal fibrosis, renal ischemia/reperfusion injury, diabetic nephropathy, polycystic kidney disease and hemodialysis...
August 10, 2017: Journal of Cellular Physiology
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